Dendrite and spine modifications in autism and related neurodevelopmental disorders in patients and animal models

Diagnostic and Statistical Manual of Mental Disorders

American Psychiatric Association (2013) · doi:10.1176/appi.books.9780890425596 · Cited by 116,369 · see citing works

Synaptic density in human frontal cortex —Developmental changes and effects of aging

Peter R., H. (1979) · Brain Research · doi:10.1016/0006-8993(79)90349-4 · Cited by 2,645 · see citing works

FMRP Stalls Ribosomal Translocation on mRNAs Linked to Synaptic Function and Autism

Darnell, J. C., Van Driesche, S. J., Zhang, C., Hung, K. Y. S., Mele, A., Fraser, C. E., Stone, E. F., Chen, C., Fak, J. J., Chi, S. W., et al. (2011) · Cell · doi:10.1016/j.cell.2011.06.013 · Cited by 2,072 · see citing works

Long-term in vivo imaging of experience-dependent synaptic plasticity in adult cortex

Trachtenberg, J. T., Chen, B. E., Knott, G. W., Feng, G., Sanes, J. R., Welker, E., & Svoboda, K. (2002) · Nature · doi:10.1038/nature01273 · Cited by 1,927 · see citing works

Axo-somatic and axo-dendritic synapses of the cerebral cortex: an electron microscope study.

Eg, G. (1959) · PubMed · Cited by 1,768 · see citing works

Association between Microdeletion and Microduplication at 16p11.2 and Autism

Weiss, L. A., Shen, Y., Korn, J. M., Arking, D. E., Miller, D. T., Fossdal, R., Saemundsen, E., Stefansson, H., Ferreira, M. A. R., Green, T., et al. (2008) · New England Journal of Medicine · doi:10.1056/nejmoa075974 · Cited by 1,666 · see citing works

Mutations in the gene encoding the synaptic scaffolding protein SHANK3 are associated with autism spectrum disorders

Durand, C. M., Betancur, C., Boeckers, T. M., Bockmann, J., Chaste, P., Fauchereau, F., Nygren, G., Rastam, M., Gillberg, I. C., Anckarsäter, H., et al. (2007) · Nature Genetics · doi:10.1038/ng1933 · Cited by 1,602 · see citing works

Selective stabilisation of developing synapses as a mechanism for the specification of neuronal networks

Changeux, J.-P., & Danchin, A. (1976) · Nature · doi:10.1038/264705a0 · Cited by 1,448 · see citing works

Extraordinary neoteny of synaptic spines in the human prefrontal cortex

Petanjek, Z., Judaš, M., Šimić, G., Rašin, M. R., Uylings, H. B. M., Rakic, P., & Kostović, I. (2011) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1105108108 · Cited by 1,411 · see citing works

The Story of Rett Syndrome: From Clinic to Neurobiology

Chahrour, M., & Zoghbi, H. Y. (2007) · Neuron · doi:10.1016/j.neuron.2007.10.001 · Cited by 1,265 · see citing works

Structure and function of dendritic spines

Nimchinsky, E. A., Sabatini, B. L., & Svoboda, K. (2002) · Annual Review of Physiology · doi:10.1146/annurev.physiol.64.081501.160008 · Cited by 1,208 · see citing works

Abnormal dendritic spines in fragile X knockout mice: Maturation and pruning deficits

Comery, T. A., Harris, J. B., Willems, P. J., Oostra, B. A., Irwin, S. A., Weiler, I. J., & Greenough, W. T. (1997) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.94.10.5401 · Cited by 1,046 · see citing works

Dendritic spines: cellular specializations imparting both stability and flexibility to synaptic function.

Harris, K., & Kater, S. (1994) · Annual Review of Neuroscience · doi:10.1146/annurev.ne.17.030194.002013 · Cited by 1,032 · see citing works

Pten Regulates Neuronal Arborization and Social Interaction in Mice

Kwon, C.-H., Luikart, B. W., Powell, C. M., Zhou, J., Matheny, S. A., Zhang, W., Li, Y., Baker, S. J., & Parada, L. F. (2006) · Neuron · doi:10.1016/j.neuron.2006.03.023 · Cited by 970 · see citing works

Structure-stability-function relationships of dendritic spines

Kasai, H., Matsuzaki, M., Noguchi, J., Yasumatsu, N., & Nakahara, H. (2003) · Trends in Neurosciences · doi:10.1016/s0166-2236(03)00162-0 · Cited by 847 · see citing works

Dendritic Spine Pathology: Cause or Consequence of Neurological Disorders?

Fiala, J. C., Spacek, J., & Harris, K. M. (2002) · Brain Research Reviews · doi:10.1016/s0165-0173(02)00158-3 · Cited by 811 · see citing works

The FMR–1 protein is cytoplasmic, most abundant in neurons and appears normal in carriers of a fragile X premutation

Devys, D., Lutz, Y., Rouyer, N., Bellocq, J., & Mandel, J. (1993) · Nature Genetics · doi:10.1038/ng0893-335 · Cited by 781 · see citing works

Neuron Number and Size in Prefrontal Cortex of Children With Autism

Courchesne, E., Mouton, P. R., Calhoun, M. E., Semendeferi, K., Ahrens-Barbeau, C., Hallet, M. J., Barnes, C. C., & Pierce, K. (2011) · JAMA · doi:10.1001/jama.2011.1638 · Cited by 779 · see citing works

Increased dendritic spine densities on cortical projection neurons in autism spectrum disorders

Hutsler, J. J., & Zhang, H. (2010) · Brain Research · doi:10.1016/j.brainres.2009.09.120 · Cited by 765 · see citing works

Regulation of Dendritic Spine Morphology and Synaptic Function by Shank and Homer

Sala, C., Piëch, V., Wilson, N. R., Passafaro, M., Liu, G., & Sheng, M. (2001) · Neuron · doi:10.1016/s0896-6273(01)00339-7 · Cited by 716 · see citing works

Association Between Microdeletion and Microduplication at 16p11.2 and Autism

Weiss, L. A., Shen, Y., Korn, J. M., Arking, D. E., Miller, D. T., Fossdal, R., Sæmundsen, E., Stefánsson, H., Ferreira, M. A. R., Green, T. J., et al. (2008) · Obstetrical & Gynecological Survey · doi:10.1097/01.ogx.0000316305.61461.6f · Cited by 647 · see citing works

The Fragile X Syndrome Protein Represses Activity-Dependent Translation through CYFIP1, a New 4E-BP

Napoli, I., Mercaldo, V., Boyl, P. P., Eleuteri, B., Zalfa, F., De Rubeis, S., Di Marino, D., Mohr, E., Massimi, M., Falconi, M., et al. (2008) · Cell · doi:10.1016/j.cell.2008.07.031 · Cited by 609 · see citing works

Partial reversal of Rett Syndrome-like symptoms in MeCP2 mutant mice

Tropea, D., Giacometti, E., Wilson, N. R., Beard, C., McCurry, C., Fu, D. D., Flannery, R., Jaenisch, R., & Sur, M. (2009) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0812394106 · Cited by 593 · see citing works

Regulation of Dendritic Morphogenesis by Ras–PI3K–Akt–mTOR and Ras–MAPK Signaling Pathways

Kumar, V., Zhang, M.-X., Swank, M. W., Kunz, J., & Wu, G.-Y. (2005) · The Journal of Neuroscience · doi:10.1523/jneurosci.2284-05.2005 · Cited by 588 · see citing works

Abnormal Development of Dendritic Spines in<i>FMR1</i>Knock-Out Mice

Nimchinsky, E. A., Oberlander, A. M., & Svoboda, K. (2001) · The Journal of Neuroscience · doi:10.1523/jneurosci.21-14-05139.2001 · Cited by 560 · see citing works

Fragile X mental retardation protein: Nucleocytoplasmic shuttling and association with somatodendritic ribosomes.

Feng, Y., Gutekunst, C.-A., Eberhart, D. E., Yi, H., Warren, S. T., & Hersch, S. M. (1997) · The Journal of Neuroscience · doi:10.1523/jneurosci.17-05-01539.1997 · Cited by 532 · see citing works

Analysis of neocortex in three males with the Fragile X syndrome

Hinton, V. J., Brown, W. T., Wisniewski, K., & Rudelli, R. D. (1991) · American Journal of Medical Genetics · doi:10.1002/ajmg.1320410306 · Cited by 527 · see citing works

Transient and enduring morphological correlates of synaptic activity and efficacy change in the rat hippocampal slice

Chang, F., & Greenough, W. T. (1984) · Brain Research · doi:10.1016/0006-8993(84)91008-4 · Cited by 523 · see citing works

Regulation of neuronal morphology and function by the tumor suppressors Tsc1 and Tsc2

Tavazoie, S. F., Alvarez, V. A., Ridenour, D. A., Kwiatkowski, D. J., & Sabatini, B. L. (2005) · Nature Neuroscience · doi:10.1038/nn1566 · Cited by 497 · see citing works

Neuron Number and Size in Prefrontal Cortex of Children With Autism

Stockman, J. A. (2012) · Yearbook of Pediatrics · doi:10.1016/j.yped.2011.12.022 · Cited by 491 · see citing works

Dendritic Spines: The Locus of Structural and Functional Plasticity

Sala, C., & Segal, M. (2014) · Physiological Reviews · doi:10.1152/physrev.00012.2013 · Cited by 465 · see citing works

Regional Dendritic and Spine Variation in Human Cerebral Cortex: a Quantitative Golgi Study

Jacobs, B. (2001) · Cerebral Cortex · doi:10.1093/cercor/11.6.558 · Cited by 423 · see citing works

The Angelman syndrome ubiquitin ligase localizes to the synapse and nucleus, and maternal deficiency results in abnormal dendritic spine morphology

Dindot, S. V., Antalffy, B. A., Bhattacharjee, M. B., & Beaudet, A. L. (2007) · Human Molecular Genetics · doi:10.1093/hmg/ddm288 · Cited by 418 · see citing works

Deletion of FMR1 in Purkinje Cells Enhances Parallel Fiber LTD, Enlarges Spines, and Attenuates Cerebellar Eyelid Conditioning in Fragile X Syndrome

Koekkoek, S. K. E., Yamaguchi, K., Milojkovic, B. A., Dortland, B. R., Ruigrok, T. J. H., Maex, R., Graaf, W. D., Smit, A. E., VanderWerf, F., Bakker, C. E., et al. (2005) · Neuron · doi:10.1016/j.neuron.2005.07.005 · Cited by 417 · see citing works

Hippocampus in autism: a Golgi analysis

Raymond, G. V., Bauman, M. L., & Kemper, T. L. (1995) · Acta Neuropathologica · doi:10.1007/s004010050401 · Cited by 387 · see citing works

Selective dendritic alterations in the cortex of Rett syndrome

Armstrong, D., Dunn, J. K., Antalffy, B., & Trivedi, R. (1995) · Journal of Neuropathology and Experimental Neurology · doi:10.1097/00005072-199503000-00006 · Cited by 378 · see citing works

Reversible Inhibition of PSD-95 mRNA Translation by miR-125a, FMRP Phosphorylation, and mGluR Signaling

Muddashetty, R. S., Nalavadi, V. C., Gross, C., Yao, X., Xing, L., Laur, O., Warren, S. T., & Bassell, G. J. (2011) · Molecular Cell · doi:10.1016/j.molcel.2011.05.006 · Cited by 364 · see citing works

Adult fragile X syndrome: Clinico-neuropathologic findings

Rudelli, R. D., Brown, W. T., Wisniewski, K., Jenkins, E. C., Laure-Kamionowska, M., Connell, F., & Wisniewski, H. M. (1985) · Acta Neuropathologica · doi:10.1007/bf00687814 · Cited by 362 · see citing works

The Number of Parvalbumin-Expressing Interneurons Is Decreased in the Medial Prefrontal Cortex in Autism

Hashemi, E., Ariza, J., Rogers, H., Noctor, S. C., & Martínez-Cerdeño, V. (2016) · Cerebral Cortex · doi:10.1093/cercor/bhw021 · Cited by 322 · see citing works

Delayed Stabilization of Dendritic Spines in Fragile X Mice

Cruz-Martin, A., Crespo, M., & Portera-Cailliau, C. (2010) · Journal of Neuroscience · doi:10.1523/jneurosci.0577-10.2010 · Cited by 321 · see citing works

DISC1 regulates new neuron development in the adult brain via modulation of AKT-mTOR signaling through KIAA1212

Kim, J. Y., Duan, X., Liu, C. Y., Jang, M.-H., Guo, J. U., Pow-anpongkul, N., Kang, E., Song, H., & Ming, G.-L. (2009) · Neuron · doi:10.1016/j.neuron.2009.08.008 · Cited by 319 · see citing works

Autism and Mental Retardation

Williams, R. S. (1980) · Archives of Neurology · doi:10.1001/archneur.1980.00500610029003 · Cited by 318 · see citing works

Prenatal development of neurons in the human prefrontal cortex. II. A quantitative Golgi study

Mrzljak, L., Uylings, H. B. M., Kostović, I., & van Eden, C. G. (1992) · The Journal of Comparative Neurology · doi:10.1002/cne.903160408 · Cited by 316 · see citing works

The MECP2 duplication syndrome

Ramocki, M. B., Tavyev, Y. J., & Peters, S. U. (2010) · American Journal of Medical Genetics Part A · doi:10.1002/ajmg.a.33184 · Cited by 303 · see citing works

Dendritic spines: from structure to in vivo function

Rochefort, N. L., & Konnerth, A. (2012) · The EMBO Reports · doi:10.1038/embor.2012.102 · Cited by 299 · see citing works

CYFIP1 Coordinates mRNA Translation and Cytoskeleton Remodeling to Ensure Proper Dendritic Spine Formation

De Rubeis, S., Pasciuto, E., Li, K. W., Fernández, E., Di Marino, D., Buzzi, A., Ostroff, L. E., Klann, E., Zwartkruis, F. J. T., Komiyama, N. H., et al. (2013) · Neuron · doi:10.1016/j.neuron.2013.06.039 · Cited by 296 · see citing works

Untangling Dendrites with Quantitative Models

Segev, I., & London, M. (2000) · Science · doi:10.1126/science.290.5492.744 · Cited by 287 · see citing works

Inhibition of p21-activated kinase rescues symptoms of fragile X syndrome in mice

Hayashi, M. L., Rao, B. S. S., Seo, J.-S., Choi, H.-S., Dolan, B. M., Choi, S.-Y., Chattarji, S., & Tonegawa, S. (2007) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0705003104 · Cited by 281 · see citing works

Lifespan Alterations of Basal Dendritic Trees of Pyramidal Neurons in the Human Prefrontal Cortex: A Layer-Specific Pattern

Petanjek, Z., Judas, M., Kostovic, I., & Uylings, H. B. M. (2008) · Cerebral Cortex · doi:10.1093/cercor/bhm124 · Cited by 273 · see citing works

Widespread changes in dendritic and axonal morphology in <i>Mecp2</i>‐mutant mouse models of rett syndrome: Evidence for disruption of neuronal networks

Belichenko, P. V., Wright, E. E., Belichenko, N. P., Masliah, E., Li, H. H., Mobley, W. C., & Francke, U. (2009) · Journal of Comparative Neurology · doi:10.1002/cne.22009 · Cited by 272 · see citing works

Dendritic spine and dendritic field characteristics of layer V pyramidal neurons in the visual cortex of fragile‐X knockout mice

Irwin, S. A., Idupulapati, M., Gilbert, M. E., Harris, J. B., Chakravarti, A. B., Rogers, E. J., Crisostomo, R. A., Larsen, B. P., Mehta, A., Alcantara, C. J., et al. (2002) · American Journal of Medical Genetics · doi:10.1002/ajmg.10500 · Cited by 270 · see citing works

Analysis of calcium channels in single spines using optical fluctuation analysis

Sabatini, B. L., & Svoboda, K. (2000) · Nature · doi:10.1038/35046076 · Cited by 269 · see citing works

MeCP2 Suppresses Nuclear MicroRNA Processing and Dendritic Growth by Regulating the DGCR8/Drosha Complex

Cheng, T.-L., Wang, Z., Liao, Q., Zhu, Y., Zhou, W.-H., Xu, W., & Qiu, Z. (2014) · Developmental Cell · doi:10.1016/j.devcel.2014.01.032 · Cited by 253 · see citing works

Prenatal development of neurons in the human prefrontal cortex: I. A qualitative Golgi study

Mrzljak, L., Uylings, H. B. M., Kostović, I., & van Eden, C. G. (1988) · The Journal of Comparative Neurology · doi:10.1002/cne.902710306 · Cited by 249 · see citing works

Synaptic integration in dendritic trees

Gulledge, A. T., Kampa, B. M., & Stuart, G. J. (2005) · Journal of Neurobiology · doi:10.1002/neu.20144 · Cited by 248 · see citing works

mTOR SignalingPreprint

Laplante, M., & Sabatini, D. M. (2011) · Cold Spring Harbor Perspectives in Biology · doi:10.1101/cshperspect.a011593 · Cited by 235 · see citing works

Rett syndrome

Belichenko, P. V., Oldfors, A., Hagberg, B. A., & Dahlström, A. B. (1994) · Neuroreport · doi:10.1097/00001756-199407000-00025 · Cited by 231 · see citing works

Sequence of abnormal dendritic spine development in primary somatosensory cortex of a mouse model of the fragile X mental retardation syndrome

Galvez, R., & Greenough, W. T. (2005) · American Journal of Medical Genetics Part A · doi:10.1002/ajmg.a.30709 · Cited by 231 · see citing works

Delayed Maturation of Neuronal Architecture and Synaptogenesis in Cerebral Cortex of<i>Mecp2</i>-Deficient Mice

Fukuda, T., Itoh, M., Ichikawa, T., Washiyama, K., & Goto, Y.-I. (2005) · Journal of Neuropathology &amp; Experimental Neurology · doi:10.1093/jnen/64.6.537 · Cited by 221 · see citing works

Ablation of the mTORC2 component rictor in brain or Purkinje cells affects size and neuron morphology

Thomanetz, V., Angliker, N., Cloëtta, D., Lustenberger, R. M., Schweighauser, M., Oliveri, F., 昇, 鈴., & Rüegg, M. A. (2013) · The Journal of Cell Biology · doi:10.1083/jcb.201205030 · Cited by 218 · see citing works

Comparative Study of Human and Mouse Postsynaptic Proteomes Finds High Compositional Conservation and Abundance Differences for Key Synaptic Proteins

Bayés, À., Collins, M. O., Croning, M. D. R., van de Lagemaat, L. N., Choudhary, J. S., & Grant, S. G. N. (2012) · PLoS ONE · doi:10.1371/journal.pone.0046683 · Cited by 216 · see citing works

Dendritic Spine Pathology in Neurodegenerative Diseases

Herms, J., & Dorostkar, M. M. (2016) · Annual Review of Pathology: Mechanisms of Disease · doi:10.1146/annurev-pathol-012615-044216 · Cited by 201 · see citing works

Germline PIK3CA and AKT1 mutations in cowden and cowden-like syndromes

Orloff, M. S., He, X., Peterson, C., Chen, F., Chen, J.-L., Mester, J. L., & Eng, C. (2013) · The American Journal of Human Genetics · doi:10.1016/j.ajhg.2012.10.021 · Cited by 201 · see citing works

MeCP2 Is Critical for Maintaining Mature Neuronal Networks and Global Brain Anatomy during Late Stages of Postnatal Brain Development and in the Mature Adult Brain

Nguyen, M. V. C., Du, F., Felice, C. A., Shan, X., Nigam, A., Mandel, G., Robinson, J. K., & Ballas, N. (2012) · Journal of Neuroscience · doi:10.1523/jneurosci.1316-12.2012 · Cited by 199 · see citing works

The autism and schizophrenia associated gene CYFIP1 is critical for the maintenance of dendritic complexity and the stabilization of mature spines

Pathania, M., Davenport, E. C., Muir, J., Sheehan, D. F., López-Doménech, G., & Kittler, J. T. (2014) · Translational Psychiatry · doi:10.1038/tp.2014.16 · Cited by 189 · cited 1× · see citing works

Dendritic spine abnormalities in the occipital cortex of C57BL/6Fmr1 knockout mice

McKinney, B. C., Grossman, A. W., Elisseou, N. M., & Greenough, W. T. (2005) · American Journal of Medical Genetics Part B: Neuropsychiatric Genetics · doi:10.1002/ajmg.b.30183 · Cited by 184 · see citing works

Actin dynamics and cofilin‐actin rods in alzheimer disease

Bamburg, J. R., & Bernstein, B. W. (2016) · Cytoskeleton · doi:10.1002/cm.21282 · Cited by 181 · see citing works

Dendritic spine dysgenesis in autism related disorders

Phillips, M. L., & Pozzo‐Miller, L. D. (2015) · Neuroscience Letters · doi:10.1016/j.neulet.2015.01.011 · Cited by 176 · see citing works

The Prader-Willi phenotype of fragile X syndrome

Nowicki, S. T., Tassone, F., Ono, M. Y., Ferranti, J., Croquette, M. F., Goodlin-Jones, B., & Hagerman, R. J. (2007) · Journal of Developmental &amp; Behavioral Pediatrics · doi:10.1097/01.dbp.0000267563.18952.c9 · Cited by 174 · see citing works

Fragile X–associated tremor/ataxia syndrome

Hagerman, P. J., & Hagerman, R. J. (2015) · Annals of the New York Academy of Sciences · doi:10.1111/nyas.12693 · Cited by 172 · see citing works

Autism spectrum disorder susceptibility gene TAOK2 affects basal dendrite formation in the neocortex

de Anda, F. C., Rosário, A. L., Durak, O., Tran, T. S., Gräff, J., Meletis, K., Rei, D., Soda, T., Madabhushi, R., Ginty, D. D., et al. (2012) · Nature Neuroscience · doi:10.1038/nn.3141 · Cited by 171 · see citing works

Fragile X-associated tremor/ataxia syndrome (FXTAS): pathology and mechanisms

Hagerman, P. J. (2013) · Acta Neuropathologica · doi:10.1007/s00401-013-1138-1 · Cited by 164 · see citing works

Dendritic Arborization and Spine Dynamics Are Abnormal in the Mouse Model of<i>MECP2</i>Duplication Syndrome

Jiang, M., Ash, R. T., Baker, S. A., Suter, B., Ferguson, A., Park, J., Rudy, J., Torsky, S. P., Chao, H.-T., Zoghbi, H. Y., et al. (2013) · The Journal of Neuroscience · doi:10.1523/jneurosci.1745-13.2013 · Cited by 129 · see citing works

Molecular basis of dendritic arborization [Review]

Urbańska, M., Błażejczyk, M., & Jaworski, J. (2008) · Acta Neurobiologiae Experimentalis · doi:10.55782/ane-2008-1695 · Cited by 125 · see citing works

Loss of mTOR repressors Tsc1 or Pten has divergent effects on excitatory and inhibitory synaptic transmission in single hippocampal neuron cultures

Weston, M. C., Chen, H., & Swann, J. W. (2014) · Frontiers in Molecular Neuroscience · doi:10.3389/fnmol.2014.00001 · Cited by 123 · see citing works

Síndrome de X Frágil

Saldarriaga, W., Tassone, F., González-Teshima, L. Y., Forero-Forero, J. V., Ayala‐Zapata, S., & Hagerman, R. J. (2014) · Colombia medica · doi:10.25100/cm.v45i4.1810 · Cited by 122 · see citing works

Somatosensory cortical barrel dendritic abnormalities in a mouse model of the fragile X mental retardation syndrome

Galvez, R., Gopal, A. R., & Greenough, W. T. (2003) · Brain Research · doi:10.1016/s0006-8993(03)02363-1 · Cited by 118 · see citing works

Postnatal maturation of layer V pyramidal neurons in the human prefrontal cortex. A quantitative Golgi analysis

Koenderink, M. J. T., & Uylings, H. B. M. (1995) · Brain Research · doi:10.1016/0006-8993(95)00206-6 · Cited by 116 · see citing works

Depletion of MAP2 expression and laminar cytoarchitectonic changes in dorsolateral prefrontal cortex in adult autistic individuals

Mukaetova‐Ladinska, E. B., Arnold, H., Jaros, E., Perry, R., & Perry, E. (2004) · Neuropathology and Applied Neurobiology · doi:10.1111/j.1365-2990.2004.00574.x · Cited by 115 · see citing works

Rearrangement of the dendritic morphology in limbic regions and altered exploratory behavior in a rat model of autism spectrum disorder

Bringas, M. E., Carvajal-Flores, F. N., López-Ramírez, T. A., Atzori, M., & Flores, G. (2013) · Neuroscience · doi:10.1016/j.neuroscience.2013.03.030 · Cited by 114 · see citing works

Dendritic vulnerability in neurodegenerative disease: insights from analyses of cortical pyramidal neurons in transgenic mouse models

Luebke, J. I., Weaver, C. M., Rocher, A. B., Rodriguez, A., Crimins, J. L., Dickstein, D. L., Wearne, S. L., & Hof, P. R. (2010) · Brain Structure and Function · doi:10.1007/s00429-010-0244-2 · Cited by 113 · see citing works

Reversal of Fragile X Phenotypes by Manipulation of AβPP/Aβ Levels in Fmr1KO Mice

Westmark, C. J., Westmark, P. R., O'Riordan, K. J., Ray, B. C., Hervey, C. M., Salamat, M. S., Abozeid, S. H., Stein, K. M., Stodola, L. A., Tranfaglia, M., et al. (2011) · PLoS ONE · doi:10.1371/journal.pone.0026549 · Cited by 110 · see citing works

Fragile X syndrome.

Saldarriaga, W., Tassone, F., González-Teshima, L. Y., Forero-Forero, J. V., Ayala‐Zapata, S., & Hagerman, R. J. (2014) · PubMed Central · Cited by 109 · see citing works

Contactins in the neurobiology of autism

Zuko, A., Kleijer, K. T. E., Oguro‐Ando, A., Kas, M. J., van Daalen, E., van der Zwaag, B., & Burbach, J. P. H. (2013) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2013.07.016 · Cited by 99 · see citing works

Postnatal maturation of the layer III pyramidal neurons in the human prefrontal cortex: a quantitative Golgi analysis

Koenderink, M. J. T., Uylings, H. B. M., & Mrzljak, L. (1994) · Brain Research · doi:10.1016/0006-8993(94)90387-5 · Cited by 98 · see citing works

Disruption of the non-canonical Wnt gene PRICKLE2 leads to autism-like behaviors with evidence for hippocampal synaptic dysfunction

Sowers, L. P., Loo, L., Wu, Y. C., Campbell, E., Ulrich, J. D., Wu, S., Paemka, L., Wassink, T. H., Meyer, K. J., Bing, X., et al. (2013) · Molecular Psychiatry · doi:10.1038/mp.2013.71 · Cited by 94 · see citing works

Regulation of dendritic spine stability

Smart, F. M., & Halpain, S. (2000) · Hippocampus · doi:10.1002/1098-1063(2000)10:5 · Cited by 93 · see citing works

The short-time structural plasticity of dendritic spines is altered in a model of Rett syndrome

Landi, S., Putignano, E., Boggio, E. M., Giustetto, M., Pizzorusso, T., & Ratto, G. M. (2011) · Scientific Reports · doi:10.1038/srep00045 · Cited by 91 · see citing works

Single-Molecule Imaging of PSD-95 mRNA Translation in Dendrites and Its Dysregulation in a Mouse Model of Fragile X Syndrome

Ifrim, M. F., Williams, K. R., & Bassell, G. J. (2015) · Journal of Neuroscience · doi:10.1523/jneurosci.2802-14.2015 · Cited by 89 · see citing works

Preliminary evidence of neuropathology in nonhuman primates prenatally exposed to maternal immune activation

Weir, R. K., Forghany, R., Smith, S. E. P., Patterson, P. H., McAllister, A. K., Schumann, C. M., & Bauman, M. D. (2015) · Brain Behavior and Immunity · doi:10.1016/j.bbi.2015.03.009 · Cited by 86 · see citing works

An Autism-Associated Variant of Epac2 Reveals a Role for Ras/Epac2 Signaling in Controlling Basal Dendrite Maintenance in Mice

Srivastava, D. P., Woolfrey, K. M., Jones, K. A., Anderson, C. T., Smith, K. R., Russell, T. A., Lee, H., Yasvoina, M. V., Wokosin, D. L., Özdi̇nler, P. H., et al. (2012) · PLoS Biology · doi:10.1371/journal.pbio.1001350 · Cited by 85 · see citing works

Organization and dynamics of the actin cytoskeleton during dendritic spine morphological remodeling

Chazeau, A., & Giannone, G. (2016) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-016-2214-1 · Cited by 85 · see citing works

Convergent evidence identifying MAP/microtubule affinity-regulating kinase 1 (MARK1) as a susceptibility gene for autism

Maussion, G., Carayol, J., Lepagnol-Bestel, A.-M., Torès, F., Loe-Mie, Y., Milbreta, U., Rousseau, F., Fontaine, K., Renaud, J., Moalic, J., et al. (2008) · Human Molecular Genetics · doi:10.1093/hmg/ddn154 · Cited by 84 · see citing works

Fragile X-associated tremor/ataxia syndrome

Leehey, M. A., & Hagerman, P. J. (2011) · Handbook of clinical neurology · doi:10.1016/b978-0-444-51892-7.00023-1 · Cited by 84 · see citing works

NuMA is a component of an insoluble matrix at mitotic spindle poles

Dionne, M. A., Howard, L., & Compton, D. A. (1999) · Cell Motility and the Cytoskeleton · doi:10.1002/(sici)1097-0169(1999)42:3 · Cited by 81 · see citing works

Loss of function of KIAA2022 causes mild to severe intellectual disability with an autism spectrum disorder and impairs neurite outgrowth

Maldergem, L. V., Hou, Q., Kalscheuer, V. M., Rio, M., Doco‐Fenzy, M., Medeira, A., de Brouwer, A. P. M., Cabrol, C., Haas, S. A., Cacciagli, P., et al. (2013) · Human Molecular Genetics · doi:10.1093/hmg/ddt187 · Cited by 80 · see citing works

Increased dendritic complexity and axonal length in cultured mouse cortical neurons overexpressing methyl-CpG-binding protein MeCP2

Jugloff, D. G. M., Jung, B., Purushotham, D., Logan, R., & Eubanks, J. H. (2005) · Neurobiology of Disease · doi:10.1016/j.nbd.2004.11.002 · Cited by 78 · see citing works

Mechanisms of Dendritic Elaboration of Sensory Neurons inDrosophila: Insights fromIn VivoTime Lapse

Williams, D. W., & Truman, J. W. (2004) · Journal of Neuroscience · doi:10.1523/jneurosci.4521-03.2004 · Cited by 77 · see citing works

Early continuous inhibition of group 1 mGlu signaling partially rescues dendritic spine abnormalities in the Fmr1 knockout mouse model for fragile X syndrome

Su, T., Fan, H.-X., Jiang, T., Sun, W.-W., Den, W.-Y., Gao, M.-M., Chen, S.-Q., Zhao, Q.-H., & Yi, Y.-H. (2011) · Psychopharmacology · doi:10.1007/s00213-010-2130-2 · Cited by 76 · see citing works

Dendritic Cytoskeletal Protein Expression in Mental Retardation: An Immunohistochemical Study of the Neocortex in Rett Syndrome

Kaufmann, W. E. (2000) · Cerebral Cortex · doi:10.1093/cercor/10.10.992 · Cited by 75 · see citing works

MeCP2 Mutation Results in Compartment-Specific Reductions in Dendritic Branching and Spine Density in Layer 5 Motor Cortical Neurons of YFP-H Mice

Stuss, D. P., Boyd, J. D., Levin, D. B., & Delaney, K. R. (2012) · PLoS ONE · doi:10.1371/journal.pone.0031896 · Cited by 70 · see citing works

Abnormal dendrite and spine morphology in primary visual cortex in the CGG knock‐in mouse model of the fragile X premutation

Berman, R. F., Murray, K. D., Arqué, G., Hunsaker, M. R., & Wenzel, H. J. (2012) · Epilepsia · doi:10.1111/j.1528-1167.2012.03486.x · Cited by 64 · see citing works

PTEN knockdown alters dendritic spine/protrusion morphology, not density

Haws, M. E., Jaramillo, T. C., Espinosa, F., Widman, A. J., Stuber, G. D., Sparta, D. R., Tye, K. M., Russo, S. J., Parada, L. F., Stavarache, M. A., et al. (2013) · The Journal of Comparative Neurology · doi:10.1002/cne.23488 · Cited by 54 · see citing works

Hippocampal CA1 Pyramidal Neurons of<i>Mecp2</i>Mutant Mice Show a Dendritic Spine Phenotype Only in the Presymptomatic Stage

Chapleau, C. A., Boggio, E. M., Calfa, G., Percy, A. K., Giustetto, M., & Pozzo-Miller, L. (2012) · Neural Plasticity · doi:10.1155/2012/976164 · Cited by 48 · see citing works

Contactin 4, -5 and -6 differentially regulate neuritogenesis while they display identical PTPRG binding sites

Mercati, O., Danckaert, A., André-Leroux, G., Bellinzoni, M., Gouder, L., Watanabe, K., Shimoda, Y., Grailhe, R., de Chaumont, F., Bourgeron, T., et al. (2013) · Biology Open · doi:10.1242/bio.20133343 · Cited by 45 · see citing works

mTOR kinase is needed for the development and stabilization of dendritic arbors in newly born olfactory bulb neurons

Skalecka, A., Liszewska, E., Bilinski, R., Gkogkas, C. G., Khoutorsky, A., Malik, A. R., Sonenberg, N., & Jaworski, J. (2016) · Developmental Neurobiology · doi:10.1002/dneu.22392 · Cited by 41 · see citing works

Effects of prenatal exposure to valproic acid on the development of juvenile-typical social play in rats

Raza, S., Himmler, B. T., Himmler, S. M., Harker, A., Kolb, B., Pellis, S. M., & Gibb, R. (2015) · Behavioural Pharmacology · doi:10.1097/fbp.0000000000000169 · Cited by 37 · see citing works

Early electron microscopic observations of synaptic structures in the cerebral cortex: a view of the contributions made by George Gray (1924–1999)

Guillery, R. W. (2000) · Trends in Neurosciences · doi:10.1016/s0166-2236(00)01635-0 · Cited by 28 · see citing works

Modest alterations in patterns of motor neuron dendrite morphology in the Fmr1 knockout mouse model for fragile X

Thomas, C. C., Combe, C. L., Dyar, K. A., & Inglis, F. M. (2008) · International Journal of Developmental Neuroscience · doi:10.1016/j.ijdevneu.2008.06.003 · Cited by 26 · see citing works

RELN-expressing neuron density in layer I of the superior temporal lobe is similar in human brains with autism and in age-matched controls

Camacho, J., Ejaz, E., Ariza, J., Noctor, S. C., & Martínez-Cerdeño, V. (2014) · Neuroscience Letters · doi:10.1016/j.neulet.2014.07.031 · Cited by 25 · see citing works

Cellular prion protein: A co-receptor mediating neuronal cofilin-actin rod formation induced by β-amyloid and proinflammatory cytokines

Walsh, K. P., Kuhn, T. B., & Bamburg, J. R. (2014) · Prion · doi:10.4161/pri.35504 · Cited by 21 · see citing works

Neuronal network formation in human cerebral cortex

Ramakers, G. J. A. (2004) · Progress in brain research · doi:10.1016/s0079-6123(04)47001-0 · Cited by 18 · see citing works

Preliminary findings suggest the number and volume of supragranular and infragranular pyramidal neurons are similar in the anterior superior temporal area of control subjects and subjects with autism

Kim, E., Camacho, J., Combs, Z., Ariza, J., Lechpammer, M., Noctor, S. C., & Martínez-Cerdeño, V. (2015) · Neuroscience Letters · doi:10.1016/j.neulet.2015.01.021 · Cited by 17 · see citing works

Activity-dependent alterations in the sensitivity to BDNF-TrkB signaling may promote excessive dendritic arborization and spinogenesis in fragile X syndrome in order to compensate for compromised postsynaptic activity

Kim, S. W., & Cho, K. (2014) · Medical Hypotheses · doi:10.1016/j.mehy.2014.07.007 · Cited by 12 · see citing works

Untitled work

Irwin (2001) · doi:10.1002/1096-8628(20010115)98:2

Microbiome–microglia connections via the gut–brain axis

Abdel-Haq, R., Schlachetzki, J. C. M., Glass, C. K., & Mazmanian, S. K. (2019) · Journal of Experimental Medicine · doi:10.1084/jem.20180794 · Cited by 471 · see citing works

The promises and challenges of human brain organoids as models of neuropsychiatric disease

Quadrato, G., Brown, J., & Arlotta, P. (2016) · Nature Medicine · doi:10.1038/nm.4214 · Cited by 304 · see citing works

The microbiota–microglia axis in central nervous system disorders

Mossad, O., & Erny, D. (2020) · Brain Pathology · doi:10.1111/bpa.12908 · Cited by 98 · see citing works

5-HT6R null mutatrion induces synaptic and cognitive defects

Sun, Z., Wang, B., Chen, C., Li, C., & Zhang, Y. (2021) · Aging Cell · doi:10.1111/acel.13369 · Cited by 35 · see citing works

The lysosome and proteostatic stress at the intersection of pediatric neurological disorders and adult neurodegenerative diseases

Lane-Donovan, C., Paredes, M., & Kao, A. W. (2025) · Progress in Neurobiology · doi:10.1016/j.pneurobio.2025.102854 · Cited by 3 · see citing works

ИСПОЛЬЗОВAНИЕ ПОТЕНЦИAЛA СОЦИAЛЬНЫХ ПAРТНЕРОВ В ПОДГОТОВКЕ БУДУЩИХ ПЕДAГОГОВ

Атабекова, Б. Б. (2024) · Habaršy. Pedagogika ġylymdary seriâsy · doi:10.51889/2959-5762.2023.80.4.019

Cloning and Characterization of Rat BAT3 cDNA

Ozaki, T., Hanaoka, E., Naka, M., et al. (1999) · DNA and Cell Biology · doi:10.1089/104454999315222 · Cited by 22 · see citing works

EFFECT OF THE NEMATODE PHASMARHABDITIS HERMAPHRODITA ON YOUNG STAGES OF THE PEST SLUG ARION LUSITANICUS

Grimm, B. (2002) · Journal of Molluscan Studies · doi:10.1093/mollus/68.1.25 · Cited by 41 · see citing works

HLA-B-associated transcript 3 (Bat3)/Scythe is essential for p300-mediated acetylation of p53Preprint

Sasaki, T., Gan, E. C., Wakeham, A. C., Kornbluth, S. A., Mak, T. W., & Okada, H. (2007) · Genes & Development · doi:10.1101/gad.1534107 · Cited by 127 · see citing works

Anthoxanthum Mosaic Virus

Catherall, P. L. (1970) · Plant Pathology · doi:10.1111/j.1365-3059.1970.tb00999.x · Cited by 6 · see citing works