Cited by 2,715Statistical Methods in Clinical TrialsStatistical Methods and Bayesian InferenceProbability and Statistical Research

More powerful procedures for multiple significance testing

Hochberg, Yosef, Benjamini, Yoav·1990·Statistics in Medicine

Abstract

The problem of multiple comparisons is discussed in the context of medical research. The need for more powerful procedures than classical multiple comparison procedures is indicated. To this end some new, general and simple procedures are discussed and demonstrated by two examples from the medical literature: the neuropsychologic effects of unidentified childhood exposure to lead, and the sleep patterns of sober chronic alcoholics.

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Crossref · 10.1002/sim.4780090710

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Authors
Hochberg, Y., & Benjamini, Y.
Affiliations
Tel Aviv University (IL)
Venue
Statistics in Medicine
Publisher
Wiley
Published
1990-07
Volume
9
Issue
7
Pages
811-818
ISSN
  • 0277-6715 (ISSN-L)
  • 1097-0258
OpenAlex
W2123830992
Cited by
2,715
References
11
Citations by year
2026: 68 · 2025: 84 · 2024: 145 · 2023: 144 · 2022: 155 · 2021: 166 · 2020: 178 · 2019: 169 · 2018: 150 · 2017: 163 · 2016: 136 · 2015: 141 · 2014: 138 · 2013: 115 · 2012: 102
FWCI
10.29
Type
journal article
Language
en
Open access
closed
Locations
  • Statistics in Medicine (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Physical Sciences › Mathematics › Statistics and Probability › Statistical Methods in Clinical Trials
  • Physical Sciences › Mathematics › Statistics and Probability › Statistical Methods and Bayesian Inference
  • Physical Sciences › Mathematics › Statistics and Probability › Probability and Statistical Research
Keywords
multiple comparisons, statistical power, family-wise error rate, medical research, childhood lead exposure, neuropsychological outcomes, chronic alcoholism, sleep patterns
MeSH terms
Alcoholism, Child, Environmental Exposure, Humans, Lead, Reaction Time, Research Design, Sleep, Statistics as Topic, Verbal Learning

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