Organoid models of human and mouse ductal pancreatic cancer

Boj, Sylvia F., Hwang, Chang-Il, Baker, Lindsey A., Chio, Iok In Christine, Engle, Dannielle D., Corbo, Vincenzo, Jager, Myrthe, Ponz-Sarvise, Mariano +40 more·2015·Cell
DOI 10.1016/j.cell.2014.12.021

Cited by (132)

Items 101–132 of 132

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  5. Targeting LKB1 in Cancer – Exposing and Exploiting Vulnerabilities
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  6. Sweat gland organoids contribute to cutaneous wound healing and sweat gland regeneration
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  7. BRCA mutational status shapes the stromal microenvironment of pancreatic cancer linking clusterin expression in cancer associated fibroblasts with HSF1 signaling
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  8. Dual inhibition of KRASG12D and pan-ERBB is synergistic in pancreatic ductal adenocarcinoma
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  9. The potential of organoids in urological cancer research
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  10. Interleukin 22 signaling regulates acinar cell plasticity to promote pancreatic tumor development in mice
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  11. A Classical Epithelial State Drives Acute Resistance to KRAS Inhibition in Pancreatic Cancer
    Singhal, Anupriya, Styers, Hannah C., Rub, Jonathan, Li, Zhuxuan, Torborg, Stefan R., Kim, Jung Yun, Grbovic-Huezo, Olivera, Feng, Huijin, Tarcan, Zeynep Cagla, Sahin Ozkan, Hulya et al. · 2024 · Cancer Discovery
  12. ID1 Mediates Escape from TGFβ Tumor Suppression in Pancreatic Cancer
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  13. The current landscape of 3D in vitro tumor models: what cancer hallmarks are accessible for drug discovery?
    Rodenhizer, Darren, Dean, Teresa, D'Arcangelo, Elisa, McGuigan, Alison P. · 2018 · Advanced Healthcare Materials
  14. Patient-derived xenograft models of pancreatic cancer: overview and comparison with other types of models
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  15. A microfluidic platform for functional testing of cancer drugs on intact tumor slices
    Rodriguez, A. D., Horowitz, L. F., Castro, K., Kenerson, H., Bhattacharjee, N., Gandhe, G., Raman, A., Monnat, R. J., Yeung, R., Rostomily, R. C. et al. · 2020 · Lab on a Chip
  16. Next-Generation Liver Medicine Using Organoid Models
    Akbari, Soheil, Arslan, Nur, Senturk, Serif, Erdal, Esra · 2019 · Frontiers in Cell and Developmental Biology
  17. Present Application and Perspectives of Organoid Imaging Technology
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  18. Conditionally reprogrammed normal and primary tumor prostate epithelial cells: a novel patient-derived cell model for studies of human prostate cancer
    Timofeeva, Olga A., Palechor-Ceron, Nancy, Li, Guanglei, Yuan, Hang, Krawczyk, Ewa, Zhong, Xiaogang, Liu, Geng, Upadhyay, Geeta, Dakic, Aleksandra, Yu, Songtao et al. · 2017 · Oncotarget
  19. Pre-clinical Models of Metastasis in Pancreatic Cancer
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  20. Arid1a restrains Kras-dependent changes in acinar cell identity
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  21. The Q61H mutation decouples KRAS from upstream regulation and renders cancer cells resistant to SHP2 inhibitors
    Gebregiworgis, Teklab, Kano, Yoshihito, St-Germain, Jonathan, Radulovich, Nikolina, Udaskin, Molly L., Mentes, Ahmet, Huang, Richard, Poon, Betty P. K., He, Wenguang, Valencia-Sama, Ivette et al. · 2021 · Nature Communications
  22. Subtypes in pancreatic ductal adenocarcinoma based on niche factor dependency show distinct drug treatment responses
    Shinkawa, Tomohiko, Ohuchida, Kenoki, Mochida, Yuki, Sakihama, Kukiko, Iwamoto, Chika, Abe, Toshiya, Ideno, Noboru, Mizuuchi, Yusuke, Shindo, Koji, Ikenaga, Naoki et al. · 2022 · Journal of Experimental &amp; Clinical Cancer Research
  23. Targeting eIF4A-Dependent Translation of KRAS Signaling Molecules
    Singh, Kamini, Lin, Jianan, Lecomte, Nicolas, Mohan, Prathibha, Gokce, Askan, Sanghvi, Viraj R., Jiang, Man, Grbovic-Huezo, Olivera, Burčul, Antonija, Stark, Stefan G. et al. · 2021 · Cancer Research
  24. Genome engineering of stem cell organoids for disease modeling
    Sun, Yingmin, Ding, Qiurong · 2017 · Protein &amp; Cell
  25. Pentose conversions support the tumorigenesis of pancreatic cancer distant metastases
    Bechard, Matthew E., Word, Anna E., Tran, Amanda V., Liu, Xiaojing, Locasale, Jason W., McDonald, Oliver G. · 2018 · Oncogene
  26. Precision medicine in pancreatic cancer — fact or fiction?
    Seufferlein, Thomas, Mayerle, Julia · 2016 · Nature Reviews Gastroenterology &amp; Hepatology
  27. Advances in Cerebral Organoid Systems and their Application in Disease Modeling
    Liu, Fangkun, Huang, Jing, Zhang, Liyang, Chen, Jindong, Zeng, Yu, Tang, Yongjian, Liu, Zhixiong · 2019 · Neuroscience
  28. PDAC as an immune evasive disease: can 3D model systems aid to tackle this clinical problem?
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  29. Implementing biological markers as a tool to guide clinical care of patients with pancreatic cancer
    Iovanna, Juan · 2021 · Translational Oncology
  30. Screening Splice-Switching Antisense Oligonucleotides in Pancreas-Cancer Organoids
    Wan, Ledong, Kral, Alexander J., Voss, Dillon, Schäfer, Balázs, Sudheendran, Kavitha, Danielsen, Mathias, Caruthers, Marvin H., Krainer, Adrian R. · 2024 · Nucleic Acid Therapeutics
  31. PDAC-on-chip for <i>in vitro</i> modeling of stromal and pancreatic cancer cell crosstalk
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  32. Reproducible Computational Workflows with Continuous Analysis
    Beaulieu-Jones, Brett K., Greene, Casey S. · 2016