Neuron-Astrocyte Metabolic Coupling Protects against Activity-Induced Fatty Acid Toxicity

Ioannou, Maria S., Jackson, Jesse, Sheu, Shu-Hsien, Chang, Chi-Lun, Weigel, Aubrey V., Liu, Hui, Pasolli, H. Amalia, Xu, C. Shan, Pang, Song, Matthies, Doreen, Hess, Harald F., Lippincott-Schwartz, Jennifer, Liu, Zhe·2019·Cell

DOI 10.1016/j.cell.2019.04.001

Cited by (761)

Items 101–200 of 761

NADPH and Mitochondrial Quality Control as Targets for a Circadian-Based Fasting and Exercise Therapy for the Treatment of Parkinson’s Disease
William M. Curtis, William A. Seeds, Mark P. Mattson, Patrick C. Bradshaw · 2022 · Cells
Disruption of lysosomal proteolysis in astrocytes facilitates midbrain organoid proteostasis failure in an early-onset Parkinson’s disease model
Gustavo Morrone Parfitt, Elena Coccia, Camille Goldman, Kristen R. Whitney, Ricardo Reyes, Lily Sarrafha, Ki Hong Nam, Soha Sohail, Drew R. Jones, John F. Crary et al. · 2024 · Nature Communications
Mitochondrial dysfunction compromises ciliary homeostasis in astrocytes
Ignatenko, Olesia, Malinen, Satu, Rybas, Sofiia, Vihinen, Helena, Nikkanen, Joni, Kononov, Aleksander, Jokitalo, Eija S., Ince-Dunn, Gulayse, Suomalainen, Anu · 2023 · Journal of Cell Biology
FSP1-mediated lipid droplet quality control prevents neutral lipid peroxidation and ferroptosis
Mike Lange, Michele Wölk, Vivian Wen Li, Cody E. Doubravsky, Joseph M. Hendricks, Shunji Kato, Yurika Otoki, Benjamin S. Styler, Sean L. Johnson, Cynthia A. Harris et al. · 2025 · Nature Cell Biology
Metabolic reprogramming in ischemic stroke: when glycolytic overdrive meets lipid storm
Yuchun Wang, Minyan Ge, Jinling Wang, Yiming Xu, Nianhong Wang, Shumao Xu · 2025 · Cell Death and Disease
Neuroinflammation in perioperative neurocognitive disorders: From bench to the bedside
Yang Liu, Huiqun Fu, Tianlong Wang · 2022 · CNS Neuroscience & Therapeutics
Driving factors of neuronal ferroptosis
Julie Jacquemyn, Isha Ralhan, Maria S. Ioannou · 2024 · Trends in Cell Biology
FABP7 upregulation induces a neurotoxic phenotype in astrocytes
Kelby M. Killoy, Benjamin A. Harlan, Mariana Pehar, Marcelo R. Vargas · 2020 · Glia
Emerging Role of Neuron‐Glia in Neurological Disorders: At a Glance
Md. Mominur Rahman, Md. Rezaul Islam, Md. Yamin, Md. Rezaul Islam, Md. Rezaul Islam, Atkia Farzana Khan Meem, Aklima Akter, Talha Bin Emran, Simona Daniela Cavalu, Rohit Sharma · 2022 · Oxidative Medicine and Cellular Longevity
Metabolic reprogramming of astrocytes in pathological conditions: implications for neurodegenerative diseases
Calì, Corrado, Cantando, Iva, Veloz Castillo, Maria Fernanda, Gonzalez, Laurine, Bezzi, Paola · 2024 · International Journal of Molecular Sciences
Modulation of Glial Function in Health, Aging, and Neurodegenerative Disease
Kendra L. Hanslik, Kaitlyn M. Marino, Tyler Kent Ulland · 2021 · Frontiers in Cellular Neuroscience
Tau is required for glial lipid droplet formation and resistance to neuronal oxidative stress
Lindsey D. Goodman, Isha Ralhan, Xin Li, Shenzhao Lu, Matthew J. Moulton, Ye-Jin Park, Pinghan Zhao, Oguz Kanca, Ziyaneh S. Ghaderpour Taleghani, Julie Jacquemyn et al. · 2024 · Nature Neuroscience
The Role of Lipids, Lipid Metabolism and Ectopic Lipid Accumulation in Axon Growth, Regeneration and Repair after CNS Injury and Disease
Debasish Roy, Andrea Tedeschi · 2021 · Cells
Pathophysiology of Lipid Droplets in Neuroglia
Tina Smolič, Robert Zorec, Nina Vardjan · 2021 · Antioxidants
Waste clearance shapes aging brain health
Li-Feng Jiang-Xie, Antoine Drieu, Jonathan Kipnis · 2024 · Neuron
Integrating single-cell and spatially resolved transcriptomic strategies to survey the astrocyte response to stroke in male mice
E. Scott, Nickie Safarian, Daniela Lozano Casasbuenas, Michael D. M. Dryden, Teodora Tockovska, Shawar Ali, Jiaxi Peng, Emerson Daniele, Isabel Nie Xin Lim, K.W. Annie Bang et al. · 2024 · Nature Communications
Gut cytokines modulate olfaction through metabolic reprogramming of glia
Xiaoyu Tracy Cai, Hongjie Li, Martin Borch Jensen, Élie Maksoud, Jovencio Borneo, Yuxin Liang, Stephen R. Quake, Liqun Luo, Ali Pejmun Haghighi, Heinrich Jasper · 2021 · Nature
Deciphering lipid dysregulation in ALS: from mechanisms to translational medicine
Ira Agrawal, Yong Shan Lim, Shi‐Yan Ng, Shuo‐Chien Ling · 2022 · Translational Neurodegeneration
New insights in lipid metabolism: potential therapeutic targets for the treatment of Alzheimer’s disease
Cao, Yuan, Zhao, Lin-Wei, Chen, Zi-Xin, Li, Shao-Hua · 2024 · Frontiers in Neuroscience
Hello from the other side: Membrane contact of lipid droplets with other organelles and subsequent functional implications
Rebekah Rakotonirina-Ricquebourg, Vítor Costa, Vítor Teixeira · 2021 · Progress in Lipid Research
Brain Lipids and Lipid Droplet Dysregulation in Alzheimer’s Disease and Neuropsychiatric Disorders
Zhao, Xiaojie, Zhang, Siwei, Sanders, Alan R., Duan, Jubao · 2023 · Complex Psychiatry
A New Hypothesis for Alzheimer’s Disease: The Lipid Invasion Model
Rudge, Jonathan D’Arcy · 2022 · Journal of Alzheimer's Disease Reports
Lipidomic analysis identifies long-chain acylcarnitine as a target for ischemic stroke
Xin-Xin Huang, Lei Li, Run‐Hao Jiang, Jian-Bing Yu, Yuqin Sun, Jinjun Shan, Jin Yang, Juan Ji, Shu-qi Cheng, Yinfeng Dong et al. · 2023 · Journal of Advanced Research
Lipid Quality Control and Ferroptosis: From Concept to Mechanism
Zhipeng Li, Mike Lange, Scott J. Dixon, James A. Olzmann · 2023 · Annual Review of Biochemistry
BACH1 changes microglial metabolism and affects astrogenesis during mouse brain development
Yanyan Wang, Wenwen Wang, Libo Su, Fen Ji, Mengtian Zhang, Yanzhen Xie, Tianyu Zhang, Jianwei Jiao · 2023 · Developmental Cell
Peculiar protrusions along tanycyte processes face diverse neural and nonneural cell types in the hypothalamic parenchyma
Roxane Pasquettaz, Irina Kolotuev, Antoine Rohrbach, Cathy Gouelle, Luc Pellerin, Fanny Langlet · 2020 · The Journal of Comparative Neurology
Gliotoxicity and Glioprotection: the Dual Role of Glial Cells
André Quincozes‐Santos, Camila Leite Santos, Rômulo Rodrigo de Souza Almeida, Amanda da Silva, Natalie K. Thomaz, Naithan Ludian Fernandes Costa, Fernanda Becker Weber, Izaviany Schmitz, Lara Scopel Medeiros, Lívia Medeiros et al. · 2021 · Molecular Neurobiology
Role of glia in optic nerve
Meysam Yazdankhah, Peng Shang, Sayan Ghosh, Stacey Hose, Haitao Liu, Joseph Weiss, Christopher Scott Fitting, Imran Ahmed Bhutto, J. Samuel Zigler, Jiang X. Qian et al. · 2020 · Progress in Retinal and Eye Research
Aging membranes: Unexplored functions for lipids in the lifespan of the central nervous system
Dorota Skowronska‐Krawczyk, Itay Budin · 2019 · Experimental Gerontology
The role of lipids in the central nervous system and their pathological implications in amyotrophic lateral sclerosis
Timothy J. Tracey, Siobhan E. Kirk, Frederik J. Steyn, Shyuan Thieu Ngo · 2020 · Seminars in Cell and Developmental Biology
A perspective on astrocyte regulation of neural circuit function and animal behavior
Johannes Hirrlinger, Axel Nimmerjahn · 2022 · Glia
Central nervous system cholesterol metabolism in health and disease
Wan Yun Ho, Hannelore Hartmann, Shuo‐Chien Ling · 2022 · IUBMB Life
Metabolic perspective of astrocyte dysfunction in Alzheimer's disease and type 2 diabetes brains
Zheng Shen, Zhengyang Li, Mengting Yu, Kai-Leng Tan, Si Xuan Chen · 2023 · Biomedicine & Pharmacotherapy
Single-cell mapping of lipid metabolites using an infrared probe in human-derived model systems
Yeran Bai, Carolina M. Camargo, Stella M.K. Glasauer, Raymond Gifford, Xinran Tian, Andrew P. Longhini, Kenneth S. Kosik · 2024 · Nature Communications
Cellular Contributors to Hypothalamic Inflammation in Obesity.
Chan Hee Lee, Kyoungho Suk, Rina Yu, Min‐Seon Kim · 2020 · PubMed Central
Transcriptomic analysis links diverse hypothalamic cell types to fibroblast growth factor 1-induced sustained diabetes remission
Marie Aare Bentsen, Dylan M. Rausch, Zaman Mirzadeh, Kenjiro Muta, Jarrad M. Scarlett, Jenny M. Brown, Vicente Herranz‐Pérez, Arian F. Baquero, Jonatan J. Thompson, Kimberly M. Alonge et al. · 2020 · Nature Communications
Insulin resistance and impaired lipid metabolism as a potential link between diabetes and Alzheimer's disease
Joshua A. Kulas, Thaddeus K. Weigel, Heather Anne Ferris · 2020 · Drug Development Research
Neuronal lipolysis participates in PUFA‐mediated neural function and neurodegeneration
Leilei Yang, Jingjing Liang, Sin Man Lam, Ahmet Yavuz, Meng Carla Wang, Guanghou Shui, Mei Ding, Xun Huang · 2020 · EMBO Reports
Functions of Stress-Induced Lipid Droplets in the Nervous System
Eva Islimye, Victor Girard, Alex P. Gould · 2022 · Frontiers in Cell and Developmental Biology
PICALM Alzheimer’s risk allele causes aberrant lipid droplets in microglia
Kozlova, Alena, Zhang, Siwei, Sudwarts, Ari, Zhang, Hanwen, Smirnou, Stanislau, Byeon, Seul Kee, Thapa, Christina, Sun, Xiaotong, Stephenson, Kimberley, Zhao, Xiaojie et al. · 2025 · Nature
Lipid metabolism in microglia: Emerging mechanisms and therapeutic opportunities for neurodegenerative diseases (Review)
Yunlong Sun, Kaifang Wei, Xudong Liao, Jianan Wang, Lina Gao, Bo Pang · 2025 · International Journal of Molecular Medicine
Brain-specific lipoprotein receptors interact with astrocyte derived apolipoprotein and mediate neuron-glia lipid shuttling
Jun Yin, Emma Spillman, Ethan S. Cheng, Jacob Short, Yang Chen, Jingce Lei, Mary Gibbs, Justin Rosenthal, Chengyu Sheng, Yuki X. Chen et al. · 2021 · Nature Communications
Expression pattern of perilipins in human brain during aging and in Alzheimer's disease
Maria Conte, Valentina Medici, Davide Malagoli, Antonio Chiariello, Alice Cirrincione, Annalisa Davin, Maia Chikhladze, Francesco Vasuri, Giuseppe Legname, Isidró Ferrer et al. · 2021 · Neuropathology and Applied Neurobiology
Lipophagy: a new player in CNS disorders
Mansour Haidar, Melanie Loix, Jeroen F. J. Bogie, Jerome J. A. Hendriks · 2021 · Trends in Endocrinology and Metabolism
Lipid Droplets and Neurodegeneration
Keya Mallick, Shuchismita Paul, Sayani Banerjee, Sugato Banerjee · 2024 · Neuroscience
The regulatory role of lipophagy in central nervous system diseases
Lan, Zhuo-qing, Ge, Zi-yi, Lv, Shu-kai, Zhao, Bing, Li, Cai-xia · 2023 · Cell Death Discovery
How expensive is the astrocyte?
Barros, LF · 2022 · Journal of Cerebral Blood Flow & Metabolism
Good, bad, and neglectful: Astrocyte changes in neurodegenerative disease
Zoeb Jiwaji, Giles E. Hardingham · 2022 · Free Radical Biology and Medicine
Neural stem cell metabolism revisited: a critical role for mitochondria
Valentina Scandella, Francesco Petrelli, Darcie L. Moore, Simon M. G. Braun, Marlen Knobloch · 2023 · Trends in Endocrinology and Metabolism
Implications of glial metabolic dysregulation in the pathophysiology of neurodegenerative diseases
Ruqayya Afridi, Md Habibur Rahman, Kyoungho Suk · 2022 · Neurobiology of Disease
The return of malonyl-CoA to the brain: Cognition and other stories
Rut Fadó, Rosalía Rodríguez‐Rodríguez, Núria Casals · 2020 · Progress in Lipid Research
Astrocytes in selective vulnerability to neurodegenerative disease
Till S. Zimmer, Adam L. Orr, Anna G. Orr · 2024 · Trends in Neurosciences
Mitochondrial heterogeneity and adaptations to cellular needs
Melia Granath-Panelo, Shingo Kajimura · 2024 · Nature Cell Biology
Modulation of glymphatic system by visual circuit activation alleviates memory impairment and apathy in a mouse model of Alzheimer’s disease
Wen Wu, Yubai Zhao, Xin Ran Cheng, Xiaoru Xie, Yixiu Zeng, Quan Tao, Yishuai Yang, Chuan Xiao, Zhan Zhang, Jiahui Pang et al. · 2025 · Nature Communications
Functional consequences of brain exposure to saturated fatty acids: From energy metabolism and insulin resistance to neuronal damage
Karina Sánchez‐Alegría, Clorinda Arias · 2022 · Endocrinology Diabetes & Metabolism
Triggering ferroptosis in neurodegenerative diseases
Triet Phu Minh Nguyen, Francesca M. Alves, Darius J.R. Lane, Ashley Ian Bush, Scott Ayton · 2025 · Trends in Neurosciences
Heterogeneity and Molecular Markers for CNS Glial Cells Revealed by Single-Cell Transcriptomics
Junjie Sun, Yixing Song, Zhiheng Chen, Jiaying Qiu, Shunxing Zhu, Liucheng Wu, Lingyan Xing · 2021 · Cellular and Molecular Neurobiology
The Role of Acyl-CoA β-Oxidation in Brain Metabolism and Neurodegenerative Diseases
Sylwia Szrok-Jurga, Jacek Turyn, Areta Hebanowska, Julian Świerczyński, Aleksandra Czumaj, Tomasz Śledziński, Ewa Stelmańska · 2023 · International Journal of Molecular Sciences
Ceramides increase mitochondrial permeabilization to trigger mtDNA-dependent inflammation in astrocytes during brain ischemia
Feng‐Qing Huang, Hongfei Wang, Tong Yang, Yang Dai, Peian Liu, Raphael Nammahime Alolga, Gaoxiang Ma, Baolin Liu, An Pan, Shijia Liu et al. · 2025 · Metabolism
Glycolytically impaired Drosophila glial cells fuel neural metabolism via β-oxidation
Ellen McMullen, Helen Hertenstein, Katrin Straßburger, Leon Deharde, Marko Brankatschk, Stefanie Schirmeier · 2023 · Nature Communications
Lipids shape brain function through ion channel and receptor modulations: physiological mechanisms and clinical perspectives
Salvatore Incontro, Maria Laura Musella, Malika Sammari, Coralie Di Scala, Jacques Fantini, Dominique Debanne · 2024 · Physiological Reviews
Lipid droplets in central nervous system and functional profiles of brain cells containing lipid droplets in various diseases
Longxiao Zhang, Yunfei Zhou, Zhongbo Yang, Liangchao Jiang, Xinyang Yan, Wenkai Zhu, Yijun Shen, Bolong Wang, Jiaxi Li, Jinning Song · 2025 · Journal of Neuroinflammation
The multifaceted roles of apolipoprotein E4 in Alzheimer’s disease pathology and potential therapeutic strategies
Yongfeng Chen, Haiping Jin, Jia Chen, Jing Li, Mihnea‐Alexandru Găman, Zhenyou Zou · 2025 · Cell Death Discovery
Leading the way in the nervous system: Lipid Droplets as new players in health and disease
Vítor Teixeira, Patrı́cia Maciel, Vítor Costa · 2020 · Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids
Microglial Lipid Biology in the Hypothalamic Regulation of Metabolic Homeostasis
Andrew Folick, Suneil K. Koliwad, Martín Valdearcos · 2021 · Frontiers in Endocrinology
Cholesterol dyshomeostasis in amyotrophic lateral sclerosis: cause, consequence, or epiphenomenon?
Hannelore Hartmann, Wan Yun Ho, Jer‐Cherng Chang, Shuo‐Chien Ling · 2021 · FEBS Journal
Astrocytes protect dopaminergic neurons against aminochrome neurotoxicity
Juan Segura‐Aguilar, Bengt Mannervik, José Inzunza, Mukesh Varshney, Ivan Nalvarte, Patricia Muñoz · 2022 · Neural Regeneration Research
Mechanisms of astrocyte aging in reactivity and disease
Gildea, Holly K., Liddelow, Shane A. · 2025 · Molecular Neurodegeneration
A Perspective on the Link between Mitochondria-Associated Membranes (MAMs) and Lipid Droplets Metabolism in Neurodegenerative Diseases
Tânia Fernandes, M. Rosário Domingues, Paula Isabel Moreira, Cláudia Pereira · 2023 · Biology
Mini-review: Brain energy metabolism and its role in animal models of depression, bipolar disorder, schizophrenia and autism
David Kolář, Lenka Kletečková, Hana Brožka, Karel Valeš · 2021 · Neuroscience Letters
Cholesterol Dysmetabolism in Alzheimer’s Disease: A Starring Role for Astrocytes?
Staurenghi, Erica, Giannelli, Serena, Testa, Gabriella, Sottero, Barbara, Leonarduzzi, Gabriella, Gamba, Paola · 2021 · Antioxidants
Astrocytic and neuronal apolipoprotein E isoforms differentially affect neuronal excitability
Konings, Sabine C., Torres-Garcia, Laura, Martinsson, Isak, Gouras, Gunnar K. · 2021 · Frontiers in Neuroscience
Pharmacological Upregulation of Microglial Lipid Droplet Alleviates Neuroinflammation and Acute Ischemic Brain Injury
Li, Huiya, Liu, Pinyi, Deng, Shiji, Zhu, Liwen, Cao, Xiang, Bao, Xinyu, Xia, Shengnan, Xu, Yun, Zhang, Bing · 2023 · Inflammation
Astrocytes in Parkinson’s Disease: From Role to Possible Intervention
Tianyou Wang, Yingqi Sun, Ulf Dettmer · 2023 · Cells
Mitochondria in Early Forebrain Development: From Neurulation to Mid-Corticogenesis
Ryann M. Fame, Maria K. Lehtinen · 2021 · Frontiers in Cell and Developmental Biology
Autolysosomal exocytosis of lipids protect neurons from ferroptosis
Isha Ralhan, Jinlan Chang, Matthew J. Moulton, Lindsey D. Goodman, Nathanael Y.J. Lee, Greg Plummer, Hilda Amalia Pasolli, Doreen Matthies, Hugo Jozef Bellen, Maria S. Ioannou · 2023 · The Journal of Cell Biology
Astrocyte in Neurological Disease: Pathogenesis and Therapy
Meihui Huang, Aoyang Long, Lingjia Hao, Zilin Shi, Mengqi Zhang · 2025 · MedComm
Early Life Stress and Metabolic Plasticity of Brain Cells: Impact on Neurogenesis and Angiogenesis
Alla B. Salmina, Yana V. Gorina, Yulia K. Komleva, Yu. A. Panina, Natalia A. Malinovskaya, Olga L. Lopatina · 2021 · Biomedicines
Neuroimmunometabolism: A New Pathological Nexus Underlying Neurodegenerative Disorders
Swarup Mitra, Avijit Banik, Sumit Saurabh, Malabika Maulik, Shailesh Khatri · 2022 · Journal of Neuroscience
ApoE4-Mediated Blood Brain Barrier Damage in Alzheimer's Disease: Progress and Prospects
Xuebin Zhou, Qiyuan Shi, Xinyue Zhang, Lili Gu, Jinhua Li, Yue Ju, Min Hu, Xia Zhao, Qin Li · 2022 · Brain Research Bulletin
Developmental neurotoxicity of PFOA exposure on hiPSC-derived cortical neurons
Shichen Wu, Junkai Xie, Han Zhao, Xihui Zhao, Oscar Fernando Sánchez, Jean‐Christophe Rochet, Jennifer L. Freeman, Chongli Yuan · 2024 · Environment International
FoxO3 deficiency in cortical astrocytes leads to impaired lipid metabolism and aggravated amyloid pathology
Shuqi Du, Feng Jin, Laure Maneix, Manasee Gedam, Yin Xu, André Catic, Meng Carla Wang, Hui Zheng · 2021 · Aging Cell
Nilotinib Improves Bioenergetic Profiling in Brain Astroglia in the 3xTg Mouse Model of Alzheimer’s Disease
Adlimoghaddam, Aida, Odero, Gary G, Glazner, Gordon, Turner, R. Scott, Albensi, Benedict C · 2021 · Aging and disease
The Janus-Faced Role of Lipid Droplets in Aging: Insights from the Cellular Perspective
Nikolaus Bresgen, Melanie Kovacs, Angelika Lahnsteiner, Thomas Klaus Felder, Mark Rinnerthaler · 2023 · Biomolecules
Metabolic flexibility ensures proper neuronal network function in moderate neuroinflammation
Bruno Chausse, Nikolai Malorny, Andrea Lewen, Gernot Poschet, Nikolaus Berndt, Oliver Kann · 2024 · Scientific Reports
Multi-functional role of apolipoprotein E in neurodegenerative diseases
Sadequl Islam, Arshad Ali Noorani, Yang Sun, Makoto Michikawa, Kun Zou · 2025 · Frontiers in Aging Neuroscience
Homeostatic regulation of lipid droplet content in mammalian oocytes and embryos
Megumi Ibayashi, Ryutaro Aizawa, Junichiro Mitsui, Satoshi Tsukamoto · 2021 · Reproduction
A high‐fat diet changes astrocytic metabolism to promote synaptic plasticity and behavior
Alexander Popov, Nadezda A. Brazhe, Anna Fedotova, Alisa B. Tiaglik, Maxim L. Bychkov, Kseniia I. Morozova, Alexey Brazhe, Dmitry A. Aronov, Ekaterina N. Lyukmanova, Natalia B. Lazareva et al. · 2022 · Acta Physiologica
Lysosomal Functions in Glia Associated with Neurodegeneration
Kreher, Conlan, Favret, Jacob, Maulik, Malabika, Shin, Daesung · 2021 · Biomolecules
Lipid droplets in pathogen infection and host immunity
Yanjie Tan, Yi Jin, Jun Yu Zhou, Yunfan Yang · 2023 · Acta Pharmacologica Sinica
Comprehensive Overview of Alzheimer’s Disease: Etiological Insights and Degradation Strategies
Manish Kumar Singh, Yoonhwa Shin, Songhyun Ju, Sunhee Han, Sung Soo Kim, Insug Kang · 2024 · International Journal of Molecular Sciences
The role of ApoE-mediated microglial lipid metabolism in brain aging and disease
Jui-Hung Jimmy Yen, I-Chen Ivorine Yu · 2023 · Immunometabolism
Cellular Specificity and Inter-cellular Coordination in the Brain Bioenergetic System: Implications for Aging and Neurodegeneration
Guoyuan Qi, Yashi Mi, Fei Yin · 2020 · Frontiers in Physiology
ADAM17‐triggered TNF signalling protects the ageing Drosophila retina from lipid droplet‐mediated degeneration
Muliyil, Sonia, Levet, Clémence, Düsterhöft, Stefan, Dulloo, Iqbal, Cowley, Sally A, Freeman, Matthew · 2020 · The EMBO Journal
GPX4 deficiency-dependent phospholipid peroxidation drives motor deficits of ALS
Long‐Fang Tu, Tian-Ze Zhang, Yang-Fan Zhou, Qingqing Zhou, Haibiao Gong, Lei Liang, Lin-Na Hai, Nan-Xin You, Yang Su, Yongjun Chen et al. · 2022 · Journal of Advanced Research
Lysosomal acidification impairment in astrocyte-mediated neuroinflammation
Jialiu Zeng, Jonathan Indajang, David Pitt, Chih Hung Lo · 2025 · Journal of Neuroinflammation
A Neuron‐Glia Co‐culture System for Studying Intercellular Lipid Transport
Maria S. Ioannou, Zhe J. Liu, Jennifer Lippincott‐Schwartz · 2019 · Current Protocols in Cell Biology
Endosomal-Lysosomal Processing of Neurodegeneration-Associated Proteins in Astrocytes
Wong, Ching-On · 2020 · International Journal of Molecular Sciences
Brain Metabolism in Health and Neurodegeneration: The Interplay Among Neurons and Astrocytes
Polina Shichkova, Jay S. Coggan, Henry Markram, Daniel X. Keller · 2024 · Cells
Lactate as an Astroglial Signal Augmenting Aerobic Glycolysis and Lipid Metabolism
Anemari Horvat, Robert Zorec, Nina Vardjan · 2021 · Frontiers in Physiology