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A pan-cancer single-cell transcriptional atlas of tumor infiltrating myeloid cells
Open accessAbstract
cDCs revealed their differences in transcription factors and external stimulus. Additionally, pro-angiogenic tumor-associated macrophages (TAMs) were characterized with diverse markers across different cancer types, and the composition of TIMs appeared to be associated with certain features of somatic mutations and gene expressions. Our results provide a systematic view of the highly heterogeneous TIMs and suggest future avenues for rational, targeted immunotherapies.
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“This is in agreement with previous observations showing low expression of Toll-like receptor (TLR) signaling genes and low innate immune activity of cDC3_LAMP348 and the “pro-inflammatory” properties of cDC2_FCN1 and cDC2_IL1B in blood51.”
From Transformer for one stop interpretable cell type annotation (2023) · cites this paper as [48]
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“On the cDCs populations, TOSICA reveals that the same cDC subsets from different tumor types are clustered together (Supplementary Fig. 12b), which is consistent with previous observations48.”
From Transformer for one stop interpretable cell type annotation (2023) · cites this paper as [48]
In the citing paper
“As interpretable trajectories, the diffusion map52 based on TOSICA attention embedding confirms two potential origins of the cDC3_LAMP3 from cDC1s and cDC2-CXCL9, as previously suggested48 (Fig. 4d).”
From Transformer for one stop interpretable cell type annotation (2023) · cites this paper as [48]
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“Furthermore, benefiting from its high resolution, TOSICA identifies several subtypes of monocytes that have not been discovered in the original publication48 (Fig. 4h), all having their own biological signatures and potentially different functions (Supplementary Fig. 12e).”
From Transformer for one stop interpretable cell type annotation (2023) · cites this paper as [48]
In the citing paper
“Furthermore, the map reveals another state transition path from cDC2 to pro-inflammatory cDC2 subtypes (Fig. 4d), which has not been observed in the previous analysis48.”
From Transformer for one stop interpretable cell type annotation (2023) · cites this paper as [48]
In the citing paper
“This dataset contains tumor infiltrating myeloid cells from multiple different tumor types [21].”
From A Deep Dive into Single-Cell RNA Sequencing Foundation Models (2023) · cites this paper as [21]
Citations
Cites
Hallmarks of Cancer: The Next Generation
Hanahan, D., & Weinberg, R. A. (2011) · Cell · doi:10.1016/j.cell.2011.02.013 · Cited by 66,590
Fast and accurate short read alignment with Burrows-Wheeler transform
Li, H., & Durbin, R. (2009) · Bioinformatics · doi:10.1093/bioinformatics/btp324 · Cited by 58,607
RSEM: accurate transcript quantification from RNA-Seq data with or without a reference genome
Li, B., & Dewey, C. N. (2011) · BMC Bioinformatics · doi:10.1186/1471-2105-12-323 · Cited by 22,179
ANNOVAR: functional annotation of genetic variants from high-throughput sequencing data
Wang, K., Li, M., & Hakonarson, H. H. (2010) · Nucleic Acids Research · doi:10.1093/nar/gkq603 · Cited by 14,724
The Molecular Signatures Database Hallmark Gene Set Collection
Liberzon, A., Birger, C., Thorvaldsdóttir, H., Ghandi, M., Mesirov, J. P., & Tamayo, P. (2015) · Cell Systems · doi:10.1016/j.cels.2015.12.004 · Cited by 13,807
Fast and accurate long-read alignment with Burrows-Wheeler transform.
Li, H., & Durbin, R. (2010) · Bioinformatics · doi:10.1093/bioinformatics/btp698 · Cited by 12,063
A framework for variation discovery and genotyping using next-generation DNA sequencing data
DePristo, M. A., Banks, E., Poplin, R. E., Garimella, K. V., Maguire, J., Hartl, C., Philippakis, A., del Angel, G., Rivas, M. A., Hanna, M., et al. (2011) · Nature Genetics · doi:10.1038/ng.806 · Cited by 11,457
SCANPY: large-scale single-cell gene expression data analysis
Wolf, F. A., Angerer, P., & Theis, F. J. (2018) · Genome Biology · doi:10.1186/s13059-017-1382-0 · Cited by 8,881
Scenic: single-cell regulatory network inference and clustering.
Aibar, S., González-Blas, C. B., Moerman, T., Huynh-Thu, V. A., Imrichova, H., Hulselmans, G., Rambow, F., Marine, J.-C., Geurts, P., Aerts, J., et al. (2017) · Nature Methods · doi:10.1038/nmeth.4463 · Cited by 6,520
Alternative activation of macrophages
Gordon, S. (2003) · Nature Reviews Immunology · doi:10.1038/nri978 · Cited by 6,189
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Items 301–400 of 1,003
Luo, Q., Dong, Z., Xie, W., Fu, X., Lin, L., Zeng, Q., Chen, Y., Ye, G., Chen, M., Hu, H., et al. (2023) · Cell Reports · doi:10.1016/j.celrep.2023.112437 · Cited by 46
Ammons, D. T., Harris, R. A., Hopkins, L. S., Kurihara, J. N., Weishaar, K. M., & DOW, S. W. (2023) · Frontiers in Immunology · doi:10.3389/fimmu.2023.1162700 · Cited by 46
Lu, X., Gou, Z., Chen, H., Li, L., Chen, F., Bao, C., Bu, H., & Zhang, Z. (2025) · The Journal of Pathology · doi:10.1002/path.6395 · Cited by 46
Self-citationImmunogenomic cancer evolution: A framework to understand cancer immunosuppression
Kumagai, S., Momoi, Y., & Nishikawa, H. (2025) · Science Immunology · doi:10.1126/sciimmunol.abo5570 · Cited by 46
Macrophages: Targets for next-generation cancer immunotherapy
Sun, X., Park, M. D., Mérad, M., & Brown, B. D. (2026) · Cancer Cell · doi:10.1016/j.ccell.2026.01.020 · Cited by 47
Understanding mast cell heterogeneity at single cell resolution
Cildir, G., Yip, K. H., Pant, H., Tergaonkar, V., Lopez, A. F., & Tumes, D. J. (2021) · Trends in Immunology · doi:10.1016/j.it.2021.04.004 · Cited by 46
Sun, Y., Yang, Q., Shen, J., Wei, T., Shen, W., Zhang, N., Luo, P., & Zhang, J. (2021) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2021.745859 · Cited by 48
Ke, Y., Zhu, J., Chu, Y., Cen, L., Fu, Y. S., Fan, X., Shao, J., Li, R., Yu, L., Liu, B., et al. (2022) · Advanced Functional Materials · doi:10.1002/adfm.202201306 · Cited by 45
Rescuing dendritic cell interstitial motility sustains antitumour immunity
Tang, H., Wei, Z., Zheng, B., Cai, Y., Wu, P., Wu, L., Ma, X., Chen, Y., Su, S., Xu, J., et al. (2025) · Nature · doi:10.1038/s41586-025-09202-9 · Cited by 45
Wilmouth, J., Olabe, J., García-García, D., Lucas, C., Guiton, R., Roucher‐Boulez, F., Dufour, D., Damon‐Soubeyrand, C., Sahut‐Barnola, I., Pointud, J., et al. (2022) · Science Advances · doi:10.1126/sciadv.add0422 · Cited by 47
Once upon a prime: DCs shape cancer immunity
Zagorulya, M., & Spranger, S. (2022) · Trends in cancer · doi:10.1016/j.trecan.2022.10.006 · Cited by 46
Human Lung Mast Cells: Therapeutic Implications in Asthma
Poto, R., Criscuolo, G., Marone, G., Brightling, C. E., & Varricchi, G. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms232214466 · Cited by 44
Fan, F., Gao, J., Zhao, Y., Wang, J., Meng, L., Ma, J., Li, T., Han, H., Lai, J., Gao, Z., et al. (2023) · Cancer Research · doi:10.1158/0008-5472.can-22-3140 · Cited by 47
van der Leun, A. M., Traets, J. J. H., Vos, J. L., Elbers, J. B. W., Patiwael, S., Qiao, X., Machuca-Ostos, M., Thommen, D. S., Haanen, J. B. A. G., Schumacher, T. N., et al. (2023) · Cancer Discovery · doi:10.1158/2159-8290.cd-22-0851 · Cited by 47
Zhang, W., & Huang, X. (2025) · Biomarker Research · doi:10.1186/s40364-025-00750-w · Cited by 44
A Deep Dive into Single-Cell RNA Sequencing Foundation Models
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Yang, S., Wang, M., Hua, Y., Li, J., Zheng, H., Cui, M., Huang, N., Liu, Q., & Liao, Q. (2024) · Cancer Letters · doi:10.1016/j.canlet.2024.216610 · Cited by 43
Li, W., Pan, L., Hong, W., Ginhoux, F., Zhang, X., Xiao, C., & Li, X. (2024) · Nature Communications · doi:10.1038/s41467-024-50478-8 · Cited by 46
Ren, F., Wang, L., Wang, Y., Wang, J., Wang, Y., Song, X., Zhang, G., Nie, F., & Lin, S. (2024) · Cell Death and Disease · doi:10.1038/s41419-024-06960-8 · Cited by 46
Zhao, R., Pan, Z., Qiu, J., Li, B., Qi, Y., Gao, Z., Qiu, W., Tang, W., Guo, X., Deng, L., et al. (2025) · 癌症:英文版 · doi:10.1002/cac2.70016 · Cited by 45
Macrophages in endometriosis: key roles and emerging therapeutic opportunities—a narrative review
Wang, X., Wu, N., & Xue, Q. (2025) · Reproductive Biology and Endocrinology · doi:10.1186/s12958-025-01471-3 · Cited by 44
Self-citationJakab, M., Rostalski, T., Lee, K. H., Mogler, C., & Augustin, H. G. (2022) · Cancer Research · doi:10.1158/0008-5472.can-21-3181 · Cited by 42
Keenan, B. P., McCarthy, E. E., Ilano, A., Yang, H., Zhang, L., Allaire, K. M., Fan, Z., Li, T. Y., Lee, D. S., Sun, Y., et al. (2022) · Cell Reports · doi:10.1016/j.celrep.2022.111384 · Cited by 46
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Turlej, E., Domaradzka, A., Radzka, J., Drulis‐Fajdasz, D., Kulbacka, J., & Gizak, A. (2025) · Cells · doi:10.3390/cells14060403 · Cited by 47
Inhibition of APOE potentiates immune checkpoint therapy for cancer
Hui, B., Lu, C., Li, H., Hao, X., Liu, H., Zhuo, D., Wang, Q., Li, Z., Liu, L., Wang, X., et al. (2022) · International Journal of Biological Sciences · doi:10.7150/ijbs.70117 · Cited by 41
Self-citationThe Advancement and Application of the Single-Cell Transcriptome in Biological and Medical Research
Huang, K., Xu, Y., Feng, T., Lan, H., Ling, F., Xiang, H., & Liu, Q. (2024) · Biology · doi:10.3390/biology13060451 · Cited by 44
Mei, S., Zhang, H., Hirz, T., Jeffries, N. E., Xu, Y., Baryawno, N., Wu, S., Wu, C., Patnaik, A., Saylor, P. J., et al. (2025) · Molecular Cancer Research · doi:10.1158/1541-7786.mcr-24-0791 · Cited by 42
Unraveling the Heterogeneity and Ontogeny of Dendritic Cells Using Single-Cell RNA Sequencing
Chen, B., Zhu, L., Yang, S., & Su, W. (2021) · Frontiers in Immunology · doi:10.3389/fimmu.2021.711329 · Cited by 43
Visser, L. L., Bleijs, M., Margaritis, T., van de Wetering, M., Holstege, F. C. P., & Clevers, H. C. (2023) · Cancer Research Communications · doi:10.1158/2767-9764.crc-23-0027 · Cited by 42
Chen, M., Ma, P., Zhang, Y., Wang, D., Yu, Z., Fu, Y., Zhao, X., Wang, M., Zhuang, G., & Jing, Y. (2023) · Journal for ImmunoTherapy of Cancer · doi:10.1136/jitc-2023-007305 · Cited by 43
Sun, R., Lei, C., Xu, Z., Gu, X., Huang, L., Chen, L., Tan, Y., Peng, M., Yaddanapudi, K., Siskind, L. J., et al. (2024) · Nature Communications · doi:10.1038/s41467-024-45084-7 · Cited by 40
Ammons, D. T., Hopkins, L. S., Cronise, K. E., Kurihara, J. N., Regan, D. P., & DOW, S. W. (2024) · Communications Biology · doi:10.1038/s42003-024-06182-w · Cited by 44
Yang, L., Li, A., Yu, W., Wang, H., Zhang, L., Wang, Y., Wang, Y., Zhang, R., Lei, Q., Liu, Z., et al. (2024) · Drug Resistance Updates · doi:10.1016/j.drup.2024.101175 · Cited by 40
Self-citationMaurer, K., Park, C. Y., Mani, S., Borji, M., Raths, F., Gouin, K. H., Penter, L., Jin, Y., Zhang, J. Y., Shin, C. S., et al. (2025) · Science Immunology · doi:10.1126/sciimmunol.adr0782 · Cited by 42
Interferon-γ orchestrates leptomeningeal anti-tumour response
Remšík, J., Tong, X., Kunes, R., Li, M., Estrera, R., Snyder, J., Thomson, C., Osman, A. M., Chabot, K., Sener, U. T., et al. (2025) · Nature · doi:10.1038/s41586-025-09012-z · Cited by 44
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Zhang, K., Mishra, A., & Jagannath, C. (2024) · Frontiers in Immunology · doi:10.3389/fimmu.2024.1363938 · Cited by 40
Lin, S., Dai, Y., Han, C., Han, T., Zhao, L., Wu, R., Liu, J., Zhang, B., Huang, N., Liu, Y., et al. (2024) · Genome Medicine · doi:10.1186/s13073-024-01325-4 · Cited by 39
Self-citationSingle-cell transcriptional atlas of tumor-associated macrophages in breast cancer
Zhang, Y., Zhong, F., & Liu, L. (2024) · Breast Cancer Research · doi:10.1186/s13058-024-01887-6 · Cited by 43
Wang, Y., Zhang, G., Zhang, X., Liu, G., Zhang, L., Chen, L., Sang, S., Yao, S., Fei, Y., Tian, Z., et al. (2025) · Nature Communications · doi:10.1038/s41467-025-65421-8 · Cited by 41
Self-citationXu, T., Liu, Z., Huang, L., Jing, J., & Liu, X. (2022) · Frontiers in Immunology · doi:10.3389/fimmu.2022.1057850 · Cited by 38
Liu, X., Liu, Y., Xu, J., Zhang, Y., Ruan, Y., Zhao, Y., Wu, L., Hu, J., Zhang, Z., He, M., et al. (2023) · Clinical and Translational Medicine · doi:10.1002/ctm2.1203 · Cited by 41
Self-citationCai, Z., Chen, L., Chen, S., Fang, R., Chen, X., & Lei, W. (2023) · Cell Communication and Signaling · doi:10.1186/s12964-023-01312-z · Cited by 41
Peng, H., Jiang, L., Yuan, J., Wu, X., Chen, N., Liu, D., Liang, Y., Xie, Y., Jia, K., Li, Y., et al. (2024) · Clinical and Translational Medicine · doi:10.1002/ctm2.70054 · Cited by 38
Self-citationKabiljo, J., Theophil, A., Homola, J., Renner, A. F., Stürzenbecher, N., Ammon, D., Zirnbauer, R., Stang, S., Tran, L., Laengle, J., et al. (2024) · Journal for ImmunoTherapy of Cancer · doi:10.1136/jitc-2024-009494 · Cited by 38
Xu, Z. Z., Kuhlmann-Hogan, A., Xu, S., Tseng, H., Chen, D., Tan, S., Sun, M. H., Tripple, V., Bosenberg, M., Miller‐Jensen, K., et al. (2024) · Cancer Research · doi:10.1158/0008-5472.can-23-4027 · Cited by 39
Transformer-Based Single-Cell Language Model: A Survey
Lan, W., He, G., Liu, M., Chen, Q., Cao, J., & Peng, W. (2024) · Big Data Mining and Analytics · doi:10.26599/bdma.2024.9020034 · Cited by 40
Peng, W.-S., Zhou, X., Yan, W.-B., Li, Y.-J., Du, C.-R., Wang, X.-S., Shen, C.-Y., Wang, Q.-F., Ying, H.-M., Lu, X.-G., et al. (2022) · OncoImmunology · doi:10.1080/2162402x.2022.2026583 · Cited by 38
Self-citationHu, Z., Li, W., Chen, S., Chen, D., Xu, R., Zheng, D., Yang, X., Li, S., Zhou, X., Niu, X., et al. (2023) · Science China Life Sciences · doi:10.1007/s11427-022-2285-6 · Cited by 38
Self-citationDietary fat and lipid metabolism in the tumor microenvironment
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Xie, Z., Zheng, G., Niu, L., Du, K., Li, R., Dan, H., Duan, L., Wu, H., Ren, G., Dou, X., et al. (2024) · Genes & Diseases · doi:10.1016/j.gendis.2024.101340 · Cited by 37
Tabe, S., Takeuchi, K., Aoshima, K., Okumura, A., Yamamoto, Y., Yanagisawa, K., Eto, R., Matsuo, M., Ueno, Y., Konishi, T., et al. (2024) · Biomaterials · doi:10.1016/j.biomaterials.2024.122838 · Cited by 37
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Liu, J., Wang, M., & Zhao, Y. X. (2025) · ImmunoTargets and Therapy · doi:10.2147/itt.s494550 · Cited by 38
Zhao, R., Hou, Y., Li, B., Pan, Z., Qiu, J., Wang, Q., Qi, Y., Han, Z. W., Zhao, H., Liu, H., et al. (2025) · Nature Communications · doi:10.1038/s41467-025-63081-2 · Cited by 40
Han, Y., Zhang, L., Sun, D., Cao, G., Wang, Y., Yue, J., Hu, J., Dong, Z., Li, F., Li, T., et al. (2025) · Nature Cancer · doi:10.1038/s43018-025-01039-5 · Cited by 40
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Lin, S., Sun, Y., Cao, C., Zhu, Z., Xu, Y., Liu, B., Hu, B., Peng, T., Zhi, W., Xu, M., et al. (2023) · EBioMedicine · doi:10.1016/j.ebiom.2023.104846 · Cited by 38
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Xu, C., Huang, K. K., Law, J. H., Chua, J. S., Sheng, T., Flores, N. M., Pizzi, M. P., Okabe, A., Tan, A. L. K., Zhu, F., et al. (2023) · Gut · doi:10.1136/gutjnl-2022-328332 · Cited by 34
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Wu, L., Hong, X., Yang, C. X., Yang, Y., Li, W., Lu, L., Cai, M., Cao, D., Zhuang, G., & Deng, L. (2023) · Science Immunology · doi:10.1126/sciimmunol.adf4919 · Cited by 36
Self-citationJiang, S., Lu, H. X., Pan, Y., Yang, A., Aikemu, A., Li, H., Hao, R., Huang, Q., Qi, X., Tao, Z., et al. (2024) · Cancer Letters · doi:10.1016/j.canlet.2024.216799 · Cited by 34
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Wang, M., Chen, Y., Tian, L. H., Wu, C., Chen, J., Hu, J., Huang, R., Wang, Y., Zhang, J., Ouyang, X., et al. (2025) · Cancer Discovery · doi:10.1158/2159-8290.cd-24-1033 · Cited by 35
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Pekayvaz, K., Kilani, B., Joppich, M., Eivers, L., Brambs, S., Knottenberg, V., Akgöl, S., Yue, K., Li, L., Martinez-Navarro, A., et al. (2025) · Immunity · doi:10.1016/j.immuni.2025.03.020 · Cited by 36
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Yin, W., Ping, Y., Li, F., Lv, S., Zhang, X., Li, X., Guo, Y. J., Liu, Q., Li, T., Yang, L., et al. (2022) · The Journal of Pathology · doi:10.1002/path.5984 · Cited by 33
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Zhang, Z., Ji, W., Huang, J., Zhang, Y., Zhou, Y., Zhang, J., Dong, Y., Yuan, T., Yang, Q., Ding, X., et al. (2022) · Clinical and Translational Medicine · doi:10.1002/ctm2.1072 · Cited by 33
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Ebeling, S., Kowalczyk, A., Pérez-Vázquez, D., & Mattiola, I. (2023) · Frontiers in Oncology · doi:10.3389/fonc.2023.1171794 · Cited by 34
Sui, Q., Hu, Z., Liang, J., Lu, T., Bian, Y., Jin, X., Li, M., Huang, Y., Yang, H., Wang, Q., et al. (2023) · Cancer Letters · doi:10.1016/j.canlet.2023.216497 · Cited by 33
Tang, W., Zhong, Y., Wei, Y., Deng, Z., Mao, J., Liu, J., Valencak, T. G., Liu, J., Xu, H., & Wang, H. (2022) · BMC Biology · doi:10.1186/s12915-022-01321-3 · Cited by 35
Ren, Y., Li, R., Feng, H., Xie, J., Gao, L., Chu, S., Li, Y., Meng, F., & Ning, Y. (2022) · Frontiers in Immunology · doi:10.3389/fimmu.2022.985187 · Cited by 32
Tumour-associated macrophages: versatile players in the tumour microenvironment
Ji, Z. Z., Chan, M. K., Chan, A. S. W., Leung, K. T., Jiang, X., To, K., Wu, Y., & Tang, P. M. (2023) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2023.1261749 · Cited by 33
Zhang, H., Zhang, P., Lin, X., Tan, L., Wang, Y., Jia, X., Wang, K., Li, X., & Sun, D. (2024) · Frontiers in Immunology · doi:10.3389/fimmu.2024.1366096 · Cited by 33
Multiplexed Imaging Mass Cytometry Analysis Characterizes the Vascular Niche in Pancreatic Cancer
Sussman, J., Kim, N., Kemp, S. B., Traum, D., Katsuda, T., Kahn, B., Xu, J., Kim, I., Eskandarian, C., Delman, D., et al. (2024) · Cancer Research · doi:10.1158/0008-5472.can-23-2352 · Cited by 32
Meng, X., Zheng, Y., Zhang, L., Liu, P., Liu, Z., & He, Y. (2024) · Cancer Research · doi:10.1158/0008-5472.can-23-1344 · Cited by 34
Self-citationChen, G., Wang, W., Wei, X., Chen, Y., Peng, L., Qu, R., Luo, Y., He, S., Liu, Y., Du, J., et al. (2024) · The Journal of Pathology · doi:10.1002/path.6343 · Cited by 32
Wu, N., Li, J., Li, L., Yang, L., Dong, L., Shen, C., Sha, S., Fu, Y., Dong, E., Zheng, F., et al. (2024) · Science Advances · doi:10.1126/sciadv.ado8366 · Cited by 33
Iron-loaded cancer-associated fibroblasts induce immunosuppression in prostate cancer
Zhang, K., Liu, K., Hu, B., Du, G., Chen, X., Xiao, L., Zhang, Y., Jiang, L., Jing, N., Cheng, C., et al. (2024) · Nature Communications · doi:10.1038/s41467-024-53233-1 · Cited by 32
Self-citationPoźniak, J., Roda, N., Landeloos, E., Antoranz, A., Herck, Y. V., Visscher, A. D., Demaerel, P. G., Vanwynsberghe, L., Declercq, J., Gkemisis, C., et al. (2025) · Cancer Discovery · doi:10.1158/2159-8290.cd-24-1208 · Cited by 33
Self-citationLin, Y., Ou, D., Su, Y., Hsu, C., Hsiao, C., Ko, B., Chen, S., Wang, J., Wang, J.-H., Wu, Y., et al. (2025) · Journal of Hepatology · doi:10.1016/j.jhep.2025.08.035 · Cited by 32
Peng, F., Sinjab, A. F., Dai, Y., Treekitkarnmongkol, W., Yang, S., Bolanos, L. I. G., Zhou, T., Chen, M., Serrano, A. G., Krishna, A., et al. (2025) · Cancer Cell · doi:10.1016/j.ccell.2025.10.004 · Cited by 34
The extracellular matrix in inflammation and cancer
Zhang, W., Xiang, Y., Lu, C., Wang, F., Ren, H., Wu, H., & Yan, M. (2026) · Molecular Biomedicine · doi:10.1186/s43556-026-00415-6 · Cited by 34
Shen, M., Du, Y., & Ye, Y. (2021) · Medical Review · doi:10.1515/mr-2021-0014 · Cited by 33
Metabolism in tumor-associated macrophages
Li, J., DeNicola, G. M., & Ruffell, B. (2022) · International review of cytology · doi:10.1016/bs.ircmb.2022.01.004 · Cited by 32
Silver, A., Feier, D., Ghosh, T., Rahman, M., Huang, J., Sarkisian, M. R., & Deleyrolle, L. P. (2022) · Frontiers in Oncology · doi:10.3389/fonc.2022.1022716 · Cited by 36
Liu, X., Lv, K., Wang, J., Lin, C., Liu, H., Zhang, H., Li, H., Gu, Y., Li, R., He, H., et al. (2023) · British Journal of Cancer · doi:10.1038/s41416-023-02336-5 · Cited by 32
Single-Cell RNA Sequencing for Studying Human Cancers
Aran, D. (2023) · Annual Review of Biomedical Data Science · doi:10.1146/annurev-biodatasci-020722-091857 · Cited by 31
Metadata
- Authors
- Cheng, S., Li, Z., Gao, R., Xing, B., Gao, Y., Yang, Y., Qin, S., Zhang, L., Ouyang, H., Du, P., Jiang, L., Zhang, B., Yang, Y., Wang, X., Ren, X., Bei, J.-X., Hu, X., Bu, Z., Ji, J., & Zhang, Z.
- Affiliations
- Peking University (CN)
- Peking University Cancer Hospital (CN)
- Peking University Third Hospital (CN)
- Sun Yat-sen University (CN)
- Corresponding author
- Bu, Zhaode
- Ji, Jiafu
- Zhang, Zemin
- ORCID
- Venue
- Cell
- Publisher
- Elsevier BV
- Published
- 2021-02
- Volume
- 184
- Issue
- 3
- Pages
- 792-809.e23
- ISSN
- 0092-8674 (ISSN-L)
- OpenAlex
- W3126902084
- Cited by
- 1,601
- References
- 84
- Citations by year
- 2026: 337 · 2025: 370 · 2024: 377 · 2023: 267 · 2022: 190 · 2021: 58
- FWCI
- 87.30
- Type
- journal article
- Language
- en
- Open access
- hybrid
- doi.org
- Licence
- Locations
- Cell (publishedVersion, cc-by-nc-nd)
- PubMed (publishedVersion)
- Funders
- National Natural Science Foundation of China
- Beijing Municipal Science and Technology Commission
- Topics
- Life Sciences › Immunology and Microbiology › Immunology › Immune cells in cancer
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Single-cell and spatial transcriptomics
- Health Sciences › Medicine › Oncology › Cancer Immunotherapy and Biomarkers
- Keywords
- tumor-infiltrating myeloid cells, pan-cancer, single-cell transcriptomics, myeloid dendritic cells, tumor-associated macrophages, myeloid heterogeneity, somatic mutations, cancer immunotherapy, tumor microenvironment
- MeSH terms
- Dendritic Cells, Female, Humans, Macrophages, Male, Mast Cells, Monocytes, Neoplasm Proteins, Neoplasms, Transcription, Genetic, Cell Lineage, Myeloid Cells, Cell Line, Tumor, Lysosomal Membrane Proteins, Single-Cell Analysis, Transcriptome, Lysosomal-Associated Membrane Protein 3
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