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Reconstruction of the tumor spatial microenvironment along the malignant-boundary-nonmalignant axis

Xun, Z., Ding, X., Zhang, Y., Zhang, B., Lai, S., Zou, D., Zheng, J., Chen, G., Su, B., Han, L., et al. (2023) · Nature Communications · doi:10.1038/s41467-023-36560-7 · Cited by 166 · see citing works

A lactate-SREBP2 signaling axis drives tolerogenic dendritic cell maturation and promotes cancer progression

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Discovering dominant tumor immune archetypes in a pan-cancer census

Combes, A. J., Samad, B., Tsui, J. L., Chew, N. W., Yan, P., Reeder, G. C., Kushnoor, D., Shen, A. S., Davidson, B. R., Barczak, A. J., et al. (2021) · Cell · doi:10.1016/j.cell.2021.12.004 · Cited by 163 · see citing works

scRNA-seq of gastric tumor shows complex intercellular interaction with an alternative T cell exhaustion trajectory

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Integrative single-cell analysis of human colorectal cancer reveals patient stratification with distinct immune evasion mechanisms

Chu, X., Li, X., Zhang, Y., Dang, G., Miao, Y., Xu, W., Wang, J., Zhang, Z., & Cheng, S. (2024) · Nature Cancer · doi:10.1038/s43018-024-00807-z · Cited by 163 · see citing works

CAF-induced physical constraints controlling T cell state and localization in solid tumours

Arpinati, L., Carradori, G., & Scherz‐Shouval, R. (2024) · Nature reviews. Cancer · doi:10.1038/s41568-024-00740-4 · Cited by 160 · see citing works

Single-cell landscape reveals active cell subtypes and their interaction in the tumor microenvironment of gastric cancer

Li, Y., Hu, X., Lin, R., Zhou, G., Zhao, L., Zhao, D., Zhang, Y., Li, W., Zhang, Y., Ma, P., et al. (2022) · Theranostics · doi:10.7150/thno.71833 · Cited by 154 · see citing works

Lymphatic-localized Treg-mregDC crosstalk limits antigen trafficking and restrains anti-tumor immunity

You, S., Li, S., Zeng, L., Song, J., Li, Z., Li, W., Ni, H., Xu, X., Deng, W., Li, H., et al. (2024) · Cancer Cell · doi:10.1016/j.ccell.2024.06.014 · Cited by 154 · see citing works

Clinical landscape of macrophage-reprogramming cancer immunotherapies

Rannikko, J. H., & Hollmén, M. (2024) · British Journal of Cancer · doi:10.1038/s41416-024-02715-6 · Cited by 153 · see citing works

Spatial landscapes of cancers: insights and opportunities

Chen, J., Larsson, L., Swarbrick, A., & Lundeberg, J. (2024) · Nature Reviews Clinical Oncology · doi:10.1038/s41571-024-00926-7 · Cited by 153 · see citing works

High-throughput single-сell sequencing in cancer research

Jia, Q., Chu, H., Jin, Z., Long, H., & Zhu, B. (2022) · Signal Transduction and Targeted Therapy · doi:10.1038/s41392-022-00990-4 · Cited by 152 · see citing works

An immune cell atlas reveals the dynamics of human macrophage specification during prenatal development

Wang, Z., Wu, Z., Wang, H., Feng, R., Wang, G., Li, M., Wang, S.-Y., Chen, X., Su, Y., Wang, J., et al. (2023) · Cell · doi:10.1016/j.cell.2023.08.019 · Cited by 152 · see citing works

Single-cell transcriptomic profiling reveals the tumor heterogeneity of small-cell lung cancer

Tian, Y., Li, Q., Yang, Z., Zhang, S., Xu, J., Wang, Z., Bai, H., Duan, J., Zheng, B. J., Li, W., et al. (2022) · Signal Transduction and Targeted Therapy · doi:10.1038/s41392-022-01150-4 · Cited by 151 · see citing works

Tumor-associated macrophage clusters linked to immunotherapy in a pan-cancer census

Wei, C., Ma, Y., Wang, M., Wang, S., Yu, W., Dong, S., Deng, W., Bie, L., Zhang, C., Shen, W., et al. (2024) · npj Precision Oncology · doi:10.1038/s41698-024-00660-4 · Cited by 50 · see citing works

Abstract 7280: Pan-cancer single-cell RNA sequencing analysis refines multiorigin monocyte and macrophage lineages

Nguyen, T. D., Lee, A., Park, H. J., Shah, N., Mandzhieva, B., Lee, D., Jung, I., & Park, W.-Y. (2026) · Cancer Research · doi:10.1158/1538-7445.am2026-7280

A single-cell pan-cancer analysis to show the variability of tumor-infiltrating myeloid cells in immune checkpoint blockade

Li, W., Pan, L., Hong, W., Ginhoux, F., Zhang, X., Xiao, C., & Li, X. (2024) · Nature Communications · doi:10.1038/s41467-024-50478-8 · Cited by 43 · see citing works

The Tumor Microenvironment Shapes Lineage, Transcriptional, and Functional Diversity of Infiltrating Myeloid Cells

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Macrophage diversity in human cancers: New insight provided by single-cell resolution and spatial context

Rakina, M. A., Larionova, I., & Kzhyshkowska, J. G. (2024) · Heliyon · doi:10.1016/j.heliyon.2024.e28332 · Cited by 79 · see citing works