Cited by 29Substance Abuse Treatment and OutcomesNeural and Behavioral Psychology StudiesNeurotransmitter Receptor Influence on Behavior

Neurobiology of adolescent substance use disorders

Sharma, Aditi, Morrow, Jonathan D.·2016·Child and Adolescent Psychiatric Clinics of North America

Abstract

There are many facets of the neurobiology of substance use that are distinct in adolescence as compared with adulthood. The adolescent brain is subject to intense subcortical reward processes, but is left with an immature prefrontal control system that is often unable to resist the pull of potentially exciting activities like substance use, even when fully aware of the dangers involved. Peer influences serve only to magnify these effects and foster more sensation-seeking, risky behavior. The unique aspects of neurobiology should be taken into consideration when designing prevention programs and clinical interventions for adolescent substance use disorders.

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Crossref · 10.1016/j.chc.2016.02.001

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Authors
Sharma, A., & Morrow, J. D.
Affiliations
  • University of Washington (US)
  • University of Michigan (US)
Corresponding author
Morrow, Jonathan D.
Venue
Child and Adolescent Psychiatric Clinics of North America
Publisher
Elsevier BV
Published
2016-07
Volume
25
Issue
3
Pages
367-375
ISSN
1056-4993 (ISSN-L)
OpenAlex
W2334486395
Cited by
29
References
59
Citations by year
2025: 2 · 2024: 2 · 2023: 2 · 2022: 6 · 2021: 3 · 2020: 4 · 2019: 4 · 2018: 2 · 2017: 4
FWCI
0.45
Type
journal article
Language
en
Open access
closed
Locations
  • Child and Adolescent Psychiatric Clinics of North America (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Medicine › Epidemiology › Substance Abuse Treatment and Outcomes
  • Life Sciences › Neuroscience › Cognitive Neuroscience › Neural and Behavioral Psychology Studies
  • Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neurotransmitter Receptor Influence on Behavior
Keywords
adolescent substance use disorders, neurobiology of addiction, adolescent brain development, reward processing, prefrontal cortex, impulsivity, peer influence, sensation seeking, risk-taking, prevention programs, clinical intervention
MeSH terms
Peer Influence, Adolescent, Brain, Female, Humans, Male, Nucleus Accumbens, Stress, Psychological, Substance-Related Disorders, Adolescent Development

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