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Polyunsaturated fatty acids and p38-MAPK link metabolic reprogramming to cytoprotective gene expression during dietary restriction

Chamoli, M., Goyala, A., Tabrez, S. S., Siddiqui, A. A., Singh, A., Antebi, A., Lithgow, G. J., Watts, J. L., & Mukhopadhyay, A. (2020) · Nature Communications · doi:10.1038/s41467-020-18690-4 · Cited by 47

Mitochondrial dysfunction, aging, and the mitochondrial unfolded protein response in Caenorhabditis elegans

Haynes, C. M., & Hekimi, S. (2022) · Genetics · doi:10.1093/genetics/iyac160 · Cited by 45

FGT-1 is the major glucose transporter in C. elegans and is central to aging pathways

Feng, Y., Williams, B. G., Koumanov, F., Wolstenholme, A. J., & Holman, G. D. (2013) · Biochemical Journal · doi:10.1042/bj20131101 · Cited by 46

High-glucose diets have sex-specific effects on aging in C. elegans: toxic to hermaphrodites but beneficial to males

Liggett, M. R., Hoy, M., Mastroianni, M., & Mondoux, M. A. (2015) · Aging · doi:10.18632/aging.100759 · Cited by 46

HIF-1 regulates insect lifespan extension by inhibiting c-Myc-TFAM signaling and mitochondrial biogenesis

Lin, X.-W., Tang, L., Yang, J., & Xu, W. (2016) · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research · doi:10.1016/j.bbamcr.2016.07.007 · Cited by 45

The Oxidative Cost of Reproduction: Theoretical Questions and Alternative Mechanisms

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Lifespan extension by peroxidase and dual oxidase-mediated ROS signaling through pyrroloquinoline quinone in C. elegans

Sasakura, H., Moribe, H., Nakano, M., Ikemoto, K., Takeuchi, K., & Mori, I. (2017) · Journal of Cell Science · doi:10.1242/jcs.202119 · Cited by 46

Principles and Therapeutic Relevance for Targeting Mitochondria in Aging and Neurodegenerative Diseases

Serviddio, G., Romano, A. D., Cassano, T., Bellanti, F., Altomare, E., & Vendemiale, G. (2011) · Current Pharmaceutical Design · doi:10.2174/138161211796904740 · Cited by 45

Peripheral modulation of antidepressant targets MAO-B and GABAAR by harmol induces mitohormesis and delays aging in preclinical models

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Adaptation and failure of pancreatic β cells in murine models with different degrees of metabolic syndrome

Medina‐Gómez, G., Yetukuri, L., Velagapudi, V., Campbell, M., Blount, M., Jimenez‐Liñan, M., Ros, M., Orešič, M., & Vidal‐Puig, A. (2009) · Disease Models & Mechanisms · doi:10.1242/dmm.003251 · Cited by 44

Loss of a Neural AMP-Activated Kinase Mimics the Effects of Elevated Serotonin on Fat, Movement, and Hormonal Secretions

Cunningham, K. A., Bouagnon, A. D., Barros, A. G. D. A., Lin, L., Malard, L. M., Romano‐Silva, M. A., & Ashrafi, K. (2014) · PLoS Genetics · doi:10.1371/journal.pgen.1004394 · Cited by 45

Antioxidant Characterization and Biological Effects of Grape Pomace Extracts Supplementation in Caenorhabditis elegans

Ayuda‐Durán, B., González‐Manzano, S., Gil‐Sánchez, I., Moreno-Arribas, M. V., Bartolomé, B., Sanz‐Buenhombre, M., Guadarrama, A., Santos‐Buelga, C., & Paramás, A. M. G. (2019) · Foods · doi:10.3390/foods8020075 · Cited by 44

A Long, Deprived Life or a Short, Sweet One?

Adler, E. M. (2007) · Science s STKE · doi:10.1126/stke.4072007tw358

D-Glucosamine supplementation extends life span of nematodes and of ageing mice

Weimer, S., Priebs, J., Kuhlow, D., Groth, M., Priebe, S., Mansfeld, J., Merry, T. L., Dubuis, S., Laube, B., Pfeiffer, A. F. H., et al. (2014) · Nature Communications · doi:10.1038/ncomms4563 · Cited by 245

How increased oxidative stress promotes longevity and metabolic health: The concept of mitochondrial hormesis (mitohormesis)

Ristow, M., & Zarse, K. (2010) · Experimental Gerontology · doi:10.1016/j.exger.2010.03.014 · Cited by 789

Reductive stress on life span extension in C. elegans

Ralser, M., & Benjamin, I. J. (2008) · BMC Research Notes · doi:10.1186/1756-0500-1-19 · Cited by 22

Investigating how germline removal and dietary restriction enable glucose-mediated lifespan extension in Caenorhabditis elegans

Reynoldson, L. (2026) · Warwick Research Archive Portal (University of Warwick) · doi:10.82444/warw.33915604