Cited by 136Neuroscience and Neuropharmacology ResearchTactile and Sensory InteractionsNeurogenesis and neuroplasticity mechanisms

Synaptic basis for developmental plasticity in somatosensory cortex

Foeller, Elisabeth, Feldman, Daniel E·2004·Current Opinion in Neurobiology

Abstract

Sensory experience drives plasticity of the body map in developing and adult somatosensory cortex, but the synaptic mechanisms underlying such plasticity are not well understood. Recently, several mechanisms that are likely to contribute to map plasticity have been directly observed in response to altered experience in vivo. These mechanisms include long-term potentiation and long-term depression at specific excitatory synapses, competition between lemniscal (barrel) and non-lemniscal (septal) processing streams, and regulation of the number of inhibitory synapses.

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Crossref · 10.1016/j.conb.2004.01.011

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63 of 63 references verified0 citation errors · 0 not checkable

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  • Critical periods for sensory plasticity occur in the same preadolescent period in which remodeling of connectivity occurs.

    “It is noteworthy that critical periods for sensory plasticity occur in the same preadolescent period in which remodeling of connectivity occurs.34, 48, 49”

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Authors
Foeller, E., & Feldman, D. E.
Affiliations
University of California San Diego (US)
Corresponding author
Feldman, Daniel E
Venue
Current Opinion in Neurobiology
Publisher
Elsevier BV
Published
2004-02
Volume
14
Issue
1
Pages
89-95
ISSN
0959-4388 (ISSN-L)
OpenAlex
W2049761309
Cited by
136
References
63
Citations by year
2025: 2 · 2024: 1 · 2023: 4 · 2022: 7 · 2021: 2 · 2020: 3 · 2019: 1 · 2018: 7 · 2017: 3 · 2016: 2 · 2015: 5 · 2014: 1 · 2013: 9 · 2012: 7
FWCI
1.23
Type
journal article
Language
en
Open access
closed
Locations
  • Current Opinion in Neurobiology (publishedVersion)
  • PubMed (publishedVersion)
Funders
National Institute of Neurological Disorders and Stroke (R01NS046652)
Topics
  • Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neuroscience and Neuropharmacology Research
  • Life Sciences › Neuroscience › Cognitive Neuroscience › Tactile and Sensory Interactions
  • Life Sciences › Neuroscience › Developmental Neuroscience › Neurogenesis and neuroplasticity mechanisms
Keywords
somatosensory cortex, synaptic plasticity, sensory experience, long-term potentiation, long-term depression, excitatory synapses, barrel cortex, inhibitory synapses, inhibitory interneurons, developmental plasticity
MeSH terms
Animals, Humans, Nerve Net, Neuronal Plasticity, Somatosensory Cortex, Synapses

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