The DOI matches its Crossref record; 5 of the 5 references it cites were found in a registry or an index.
Prebiotics: why definitions matter
Open accessAbstract
The prebiotic concept was introduced twenty years ago, and despite several revisions to the original definition, the scientific community has continued to debate what it means to be a prebiotic. How prebiotics are defined is important not only for the scientific community, but also for regulatory agencies, the food industry, consumers and healthcare professionals. Recent developments in community-wide sequencing and glycomics have revealed that more complex interactions occur between putative prebiotic substrates and the gut microbiota than previously considered. A consensus among scientists on the most appropriate definition of a prebiotic is necessary to enable continued use of the term.
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Cites
Ramirez-Farias, C., Slezak, K., Fuller, Z., Duncan, A., Holtrop, G., & Louis, P. (2008) · British Journal of Nutrition · doi:10.1017/s0007114508019880 · Cited by 822
Martínez, I., Kim, J., Duffy, P. R., Schlegel, V. L., & Walter, J. (2010) · PLoS ONE · doi:10.1371/journal.pone.0015046 · Cited by 645
Martens, E. C., Kelly, A. G., Tauzin, A. S., & Brumer, H. (2014) · Journal of Molecular Biology · doi:10.1016/j.jmb.2014.06.022 · Cited by 235
Self-citationManipulation of the Microbiota for Treatment of IBS and IBD—Challenges and Controversies
Shanahan, F., & Quigley, E. M. M. (2014) · Gastroenterology · doi:10.1053/j.gastro.2014.01.050 · Cited by 172 · cited 1×
“The necessity for open discussion about this topic is reflected in that the very basis for defining prebiotics has recently been challenged [45,46].”
BackgroundKong, L. C., Holmes, B. A., Cotillard, A., Habi-Rachedi, F., Brazeilles, R., Gougis, S., Gausserès, N., Cani, P. D., Fellahi, S., Bastard, J.-P., et al. (2014) · PLoS ONE · doi:10.1371/journal.pone.0109434 · Cited by 132
Self-citation
Cited by
Benefaction of probiotics for human health: A review
George Kerry, R., Patra, J. K., Gouda, S., Park, Y., Shin, H.-S., & Das, G. (2018) · Journal of Food and Drug Analysis · doi:10.1016/j.jfda.2018.01.002 · Cited by 898
Interactions of commensal and pathogenic microorganisms with the intestinal mucosal barrier
Martens, E. C., Neumann, M., & Desai, M. S. (2018) · Nature Reviews Microbiology · doi:10.1038/s41579-018-0036-x · Cited by 711
Self-citationShaping the Future of Probiotics and Prebiotics
Cunningham, M., Azcarate-Peril, M. A., Barnard, A., Benoit, V., Grimaldi, R., Guyonnet, D., Holscher, H. D., Hunter, K., Manurung, S., Obis, D., et al. (2021) · Trends in Microbiology · doi:10.1016/j.tim.2021.01.003 · Cited by 637
Prebiotic inulin-type fructans induce specific changes in the human gut microbiota
Vandeputte, D., Falony, G., Vieira-Silva, S., Wang, J., Sailer, M., Theis, S., Verbeke, K., & Raes, J. (2017) · Gut · doi:10.1136/gutjnl-2016-313271 · Cited by 554
Immunomodulatory Effects of Probiotics on Cytokine Profiles
Azad, M. A. K., Sarker, M., & Wan, D. (2018) · BioMed Research International · doi:10.1155/2018/8063647 · Cited by 521
Metadata
- Authors
- Hutkins, R. W., Krumbeck, J. A., Bindels, L. B., Cani, P. D., Fahey, G., Goh, Y. J., Hamaker, B., Martens, E. C., Mills, D. A., Rastal, R. A., Vaughan, E., & Sanders, M. E.
- Venue
- Current Opinion in Biotechnology
- Publisher
- Elsevier BV
- Published
- 2016-02
- Volume
- 37
- Pages
- 1-7
- ISSN
- 0958-1669 (ISSN-L)
- OpenAlex
- W1778260808
- Cited by
- 437
- References
- 5
- FWCI
- 4.97
- Type
- journal article
- Language
- en
- Open access
- green
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- Hutkins, R. W., Krumbeck, J. A., Bindels, L. B., Cani, P. D., Fahey, G., Goh, Y. J., Hamaker, B., Martens, E. C., Mills, D. A., Rastal, R. A., Vaughan, E., & Sanders, M. E. (2016). Prebiotics: why definitions matter. Current Opinion in Biotechnology. https://doi.org/10.1016/j.copbio.2015.09.001
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
