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Single-cell gene expression profiling and cell state dynamics: collecting data, correlating data points and connecting the dots
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“GRNs, which control these profiles, are the underlying systems that drive cell state transitions (23).”
From Behavior-related gene regulatory networks: A new level of organization in the brain (2020) · cites this paper as [23]
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Spatially resolved, highly multiplexed RNA profiling in single cells
Chen, K. H., Boettiger, A. N., Moffitt, J. R., Wang, S., & Zhuang, X. (2015) · Science · doi:10.1126/science.aaa6090 · Cited by 2,969
Single-cell chromatin accessibility reveals principles of regulatory variation
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Unbiased classification of sensory neuron types by large-scale single-cell RNA sequencing
Usoskin, D., Furlan, A., Islam, S., Abdo, H., Lönnerberg, P., Lou, D., Hjerling-Leffler, J., Haeggström, J., Kharchenko, O., Kharchenko, P. V., et al. (2015) · Nature Neuroscience · doi:10.1038/nn.3881 · Cited by 2,136
Single-cell Hi-C reveals cell-to-cell variability in chromosome structure
Nagano, T., Lubling, Y., Stevens, T. J., Schoenfelder, S., Yaffe, E., Dean, W., Laue, E. D., Tanay, A., & Fraser, P. (2013) · Nature · doi:10.1038/nature12593 · Cited by 1,589
Comparative Analysis of Single-Cell RNA Sequencing Methods
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Multiplex single-cell profiling of chromatin accessibility by combinatorial cellular indexing
Cusanovich, D. A., Daza, R., Adey, A., Pliner, H. A., Christiansen, L., Gunderson, K. L., Steemers, F. J., Trapnell, C., & Shendure, J. (2015) · Science · doi:10.1126/science.aab1601 · Cited by 1,248
Single-cell messenger RNA sequencing reveals rare intestinal cell types
Grün, D., Lyubimova, A., Kester, L., Wiebrands, K., Basak, O., Sasaki, N., Clevers, H., & van Oudenaarden, A. (2015) · Nature · doi:10.1038/nature14966 · Cited by 1,234
Quantitative single-cell RNA-seq with unique molecular identifiers
Islam, S., Zeisel, A., Joost, S., La Manno, G., Zajac, P., Kasper, M., Lönnerberg, P., & Linnarsson, S. (2014) · Nature Methods · doi:10.1038/nmeth.2772 · Cited by 1,183
Computational and analytical challenges in single-cell transcriptomics
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Cited by
Bargaje, R., Trachana, K., Shelton, M. N., McGinnis, C. S., Zhou, J. X., Chadick, C., Cook, S., Cavanaugh, C., Huang, S., & Hood, L. (2017) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1621412114 · Cited by 115
Self-citationUsing single‐cell multiple omics approaches to resolve tumor heterogeneity
Ortega, M. A., Poirion, O., Zhu, X., Huang, S., Wolfgruber, T. K., Sebra, R., & Garmire, L. X. (2017) · Clinical and Translational Medicine · doi:10.1186/s40169-017-0177-y · Cited by 81
Self-citationBehavior-related gene regulatory networks: A new level of organization in the brain
Sinha, S., Jones, B. M., Traniello, I. M., Bukhari, S. A., Halfon, M. S., Hofmann, H. A., Huang, S., Katz, P. S., Keagy, J., Lynch, V. J., et al. (2020) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1921625117 · Cited by 85
Self-citation
Metadata
- Authors
- Marr, C., Zhou, J. X., & Huang, S.
- Venue
- Current Opinion in Biotechnology
- Publisher
- Elsevier BV
- Published
- 2016-06
- Volume
- 39
- Pages
- 207-214
- ISSN
- 0958-1669
- PMC
- PMC5130334
- Cited by
- 35
- References
- 19
- Language
- en
- Licence
- www.elsevier.com/tdm/userlicense/1.0/ (tdm)
- www.elsevier.com/legal/tdmrep-license (tdm)
- Funders
- German Science Foundation DFG
- National Institutes of Health (R01GM987654)
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- Marr, C., Zhou, J. X., & Huang, S. (2016). Single-cell gene expression profiling and cell state dynamics: collecting data, correlating data points and connecting the dots. Current Opinion in Biotechnology. https://doi.org/10.1016/j.copbio.2016.04.015
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