How the gut microbiome regulates host immune responses to viral vaccines

Human gut microbiome viewed across age and geography

Yatsunenko, T., Rey, F. E., Manary, M. J., Trehan, I., Dominguez-Bello, M. G., Contreras, M., Magris, M., Hidalgo, G., Baldassano, R. N., Anokhin, A. P., et al. (2012) · Nature · doi:10.1038/nature11053 · Cited by 7,815 · see citing works

Host-gut microbiota metabolic interactions

Nicholson, J. K., Holmes, E., Kinross, J., Burcelin, R., Gibson, G., Jia, W., & Pettersson, S. (2012) · Science · doi:10.1126/science.1223813 · Cited by 4,760 · see citing works

Richness of human gut microbiome correlates with metabolic markers

Le Chatelier, E., Nielsen, T., Qin, J., Prifti, E., Hildebrand, F., Falony, G., Almeida, M., Arumugam, M., Batto, J.-M., Kennedy, S., et al. (2013) · Nature · doi:10.1038/nature12506 · Cited by 4,662 · see citing works

Recognition of Commensal Microflora by Toll-Like Receptors Is Required for Intestinal Homeostasis

Rakoff-Nahoum, S., Paglino, J., Eslami-Varzaneh, F., Edberg, S., & Medzhitov, R. (2004) · Cell · doi:10.1016/j.cell.2004.07.002 · Cited by 4,251 · see citing works

Interactions Between the Microbiota and the Immune System

Hooper, L. V., Littman, D. R., & Macpherson, A. J. (2012) · Science · doi:10.1126/science.1223490 · Cited by 4,173 · see citing works

Role of the gut microbiota in immunity and inflammatory disease

Kamada, N., Seo, S.-U., Chen, G. Y., & Núñez, G. (2013) · Nature reviews. Immunology · doi:10.1038/nri3430 · Cited by 2,256 · see citing works

Factors influencing the composition of the intestinal microbiota in early infancy

Penders, J., Thijs, C., Vink, C., Stelma, F. F., Snijders, B., Kummeling, I., van den Brandt, P. A., & Stobberingh, E. E. (2006) · PEDIATRICS · doi:10.1542/peds.2005-2824 · Cited by 2,232 · see citing works

Dysbiosis of the gut microbiota in disease

Carding, S., Verbeke, K., Vipond, D. T., Corfe, B. M., & Owen, L. J. (2015) · Microbial Ecology in Health & Disease · doi:10.3402/mehd.v26.26191 · Cited by 1,710 · see citing works

Gut-Residing Segmented Filamentous Bacteria Drive Autoimmune Arthritis via T Helper 17 Cells

Wu, H.-J., Ivanov, I. I., Darce, J., Hattori, K., Shima, T., Umesaki, Y., Littman, D. R., Benoist, C., & Mathis, D. (2010) · Immunity · doi:10.1016/j.immuni.2010.06.001 · Cited by 1,577 · see citing works

The gastrointestinal mucus system in health and disease

Johansson, M. E. V., Sjövall, H., & Hansson, G. C. (2013) · Nature Reviews Gastroenterology & Hepatology · doi:10.1038/nrgastro.2013.35 · Cited by 1,438 · see citing works

The role of gut microbiota in immune homeostasis and autoimmunity

Wu, H.-J., & Wu, E. (2012) · Gut Microbes · doi:10.4161/gmic.19320 · Cited by 1,426 · see citing works

Persistent gut microbiota immaturity in malnourished Bangladeshi children

Subramanian, S., Huq, S., Yatsunenko, T., Haque, R., Mahfuz, M., Alam, M. A., Benezra, A., DeStefano, J., Meier, M. F., Muegge, B. D., et al. (2014) · Nature · doi:10.1038/nature13421 · Cited by 1,270 · see citing works

Gut immune maturation depends on colonization with a host-specific microbiota

Chung, H., Pamp, S. J., Hill, J. A., Surana, N. K., Edelman, S. M., Troy, E. B., Reading, N. C., Villablanca, E. J., Wang, S., Mora, J. R., et al. (2012) · Cell · doi:10.1016/j.cell.2012.04.037 · Cited by 1,241 · see citing works

Recognition of peptidoglycan from the microbiota by Nod1 enhances systemic innate immunity

Clarke, T. B., Davis, K. M., Lysenko, E. S., Zhou, A. Y., Yu, Y., & Weiser, J. N. (2010) · Nature Medicine · doi:10.1038/nm.2087 · Cited by 1,154 · see citing works

Lymphoid tissue genesis induced by commensals through NOD1 regulates intestinal homeostasis

Bouskra, D., Brézillon, C., Bérard, M., Werts, C., Varona, R., Boneca, I. G., & Eberl, G. (2008) · Nature · doi:10.1038/nature07450 · Cited by 1,107 · see citing works

Generation of Gut-Homing IgA-Secreting B Cells by Intestinal Dendritic Cells

Mora, J. R., Iwata, M., Eksteen, B., Song, S., Junt, T., Senman, B. C., Otipoby, K. L., Yokota, A., Takeuchi, H., Ricciardi‐Castagnoli, P., et al. (2006) · Science · doi:10.1126/science.1132742 · Cited by 1,014 · see citing works

Commensal bacteria calibrate the activation threshold of innate antiviral immunity

Abt, M. C., Osborne, L. C., Monticelli, L. A., Doering, T. A., Alenghat, T., Sonnenberg, G. F., Paley, M. A., Antenus, M., Williams, K. L., Erikson, J., et al. (2012) · Immunity · doi:10.1016/j.immuni.2012.04.011 · Cited by 993 · see citing works

Efficacy of pentavalent rotavirus vaccine against severe rotavirus gastroenteritis in infants in developing countries in Asia: a randomised, double-blind, placebo-controlled trial

Zaman, K., Anh, D. D., Victor, J. C., Shin, S., Yunus, M., Dallas, M. J., Podder, G., Thiem, V. D., Mai, L. T. P., Luby, S. P., et al. (2010) · The Lancet · doi:10.1016/s0140-6736(10)60755-6 · Cited by 826 · see citing works

Use of axenic animals in studying the adaptation of mammals to their commensal intestinal microbiota

Smith, K., McCoy, K. D., & Macpherson, A. J. (2006) · Seminars in Immunology · doi:10.1016/j.smim.2006.10.002 · Cited by 789 · see citing works

Gut bacteria that prevent growth impairments transmitted by microbiota from malnourished children

Blanton, L. V., Charbonneau, M. R., Salih, T., Barratt, M. J., Venkatesh, S., Ilkaveya, O., Subramanian, S., Manary, M. J., Trehan, I., Jorgensen, J. M., et al. (2016) · Science · doi:10.1126/science.aad3311 · Cited by 735 · see citing works

Systemic gut microbial modulation of bile acid metabolism in host tissue compartments

Swann, J. R., Want, E. J., Geier, F. M., Spagou, K., Wilson, I. D., Sidaway, J. E., Nicholson, J. K., & Holmes, E. (2011) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1006734107 · Cited by 726 · see citing works

Efficacy of pentavalent rotavirus vaccine against severe rotavirus gastroenteritis in infants in developing countries in sub-Saharan Africa: a randomised, double-blind, placebo-controlled trial

Armah, G. E., Sow, S. O., Breiman, R. F., Dallas, M. J., Tapia, M. D., Feikin, D. R., Binka, F. N., Steele, A. D., Laserson, K. F., Ansah, N. A., et al. (2010) · The Lancet · doi:10.1016/s0140-6736(10)60889-6 · Cited by 657 · see citing works

NOD2-mediated dysbiosis predisposes mice to transmissible colitis and colorectal cancer

Couturier-Maillard, A., Sécher, T., Rehman, A., Normand, S., Arcangelis, A. D., Häsler, R., Huot, L., Grandjean, T., Bressenot, A., Delanoye, A., et al. (2013) · Journal of Clinical Investigation · doi:10.1172/jci62236 · Cited by 571 · see citing works

Sequence and Expression of a Candidate for the Human Secretor Blood Group α(1,2)Fucosyltransferase Gene (FUT2)

Kelly, R. J., Rouquier, S., Giorgi, D., Lennon, G. G., & Lowe, J. B. (1995) · Journal of Biological Chemistry · doi:10.1074/jbc.270.9.4640 · Cited by 570 · see citing works

The Role of Retinoic Acid in Tolerance and Immunity

Hall, J. A., Grainger, J. R., Spencer, S. P., & Belkaid, Y. (2011) · Immunity · doi:10.1016/j.immuni.2011.07.002 · Cited by 556 · see citing works

Malnutrition as an enteric infectious disease with long-term effects on child development

Guerrant, R. L., Oriá, R. B., Moore, S. R., Oriá, M. O. B., & Lima, A. Â. M. (2008) · Nutrition Reviews · doi:10.1111/j.1753-4887.2008.00082.x · Cited by 544 · see citing works

Norwalk virus binds to histo-blood group antigens present on gastroduodenal epithelial cells of secretor individuals

Marionneau, S., Ruvoën, N., Le Moullac–Vaidye, B., Clement, M., Cailleau–Thomas, A., Ruiz–Palacois, G., Huang, P., Jiang, X., & Le Pendu, J. (2002) · Gastroenterology · doi:10.1053/gast.2002.33661 · Cited by 526 · see citing works

ABH and Related Histo‐Blood Group Antigens; Immunochemical Differences in Carrier Isotypes and Their Distribution1

Clausen, H., & Hakomori, S. (1989) · Vox Sanguinis · doi:10.1111/j.1423-0410.1989.tb03040.x · Cited by 507 · see citing works

Innate and Adaptive Immunity Cooperate Flexibly to Maintain Host-Microbiota Mutualism

Slack, E. M. C., Hapfelmeier, S., Stecher, B., Velykoredko, Y., Stoel, M., Lawson, M. A., Geuking, M. B., Beutler, B., Tedder, T. F., Hardt, W., et al. (2009) · Science · doi:10.1126/science.1172747 · Cited by 503 · see citing works

Probiotics-host communication

Thomas, C. M., & Versalovic, J. A. (2010) · Gut Microbes · doi:10.4161/gmic.1.3.11712 · Cited by 458 · see citing works

Environmental enteropathy: critical implications of a poorly understood condition

Korpe, P. S., & Petri, W. A. (2012) · Trends in Molecular Medicine · doi:10.1016/j.molmed.2012.04.007 · Cited by 449 · see citing works

Noroviruses bind to human ABO, Lewis, and secretor histo-blood group antigens: identification of 4 distinct strain-specific patterns.

Huang, P., Farkas, T., Marionneau, S., Zhong, W., Ruvoen-Clouet, N., Morrow, A., Altaye, M., Pickering, L., Newburg, D., Pendu, J. L., et al. (2003) · Journal of Infectious Diseases · doi:10.1086/375742 · Cited by 429 · see citing works

Inhibition of the interaction between the SARS-CoV Spike protein and its cellular receptor by anti-histo-blood group antibodies

Guillon, P., Clément, M., Sebille, V., Rivain, J.-G., Chou, C.-F., Ruvoën‐Clouet, N., & LePendu, J. (2008) · Glycobiology · doi:10.1093/glycob/cwn093 · Cited by 413 · see citing works

The role of the immune system in governing host-microbe interactions in the intestine

Brown, E., Sadarangani, M., & Finlay, B. B. (2013) · Nature Immunology · doi:10.1038/ni.2611 · Cited by 403 · see citing works

Essential Role for Retinoic Acid in the Promotion of CD4+ T Cell Effector Responses via Retinoic Acid Receptor Alpha

Hall, J. A., Cannons, J. L., Grainger, J. R., dos Santos, L. M., Hand, T. W., Naik, S., Wohlfert, E. A., Chou, D. B., Oldenhove, G., Robinson, M., et al. (2011) · Immunity · doi:10.1016/j.immuni.2011.03.003 · Cited by 375 · see citing works

Improved immunogenicity of oral D x RRV reassortant rotavirus vaccine by Lactobacillus casei GG

Isolauri, E., Joensuu, J., Suomalainen, H., Luomala, M., & Vesikari, T. (1995) · Vaccine · doi:10.1016/0264-410x(95)93319-5 · Cited by 370 · see citing works

Effect of Breast and Formula Feeding on Gut Microbiota Shaping in Newborns

Guaraldi, F., & Salvatori, G. (2012) · Frontiers in Cellular and Infection Microbiology · doi:10.3389/fcimb.2012.00094 · Cited by 365 · see citing works

Colonic mucosa-associated microbiota is influenced by an interaction of Crohn disease and FUT2 ( Secretor ) genotype

Rausch, P., Rehman, A., Künzel, S., Häsler, R., Ott, S. J., Schreiber, S., Rosenstiel, P. C., Franke, A., & Baines, J. F. (2011) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1106408108 · Cited by 348 · see citing works

ABH and Lewis histo-blood group antigens, a model for the meaning of oligosaccharide diversity in the face of a changing world.

Marionneau, S., Cailleau-Thomas, A., Rocher, J., le Moullac-Vaidye, B., Ruvoën, N., Clément, M., & Pendu, J. L. (2001) · Biochimie · doi:10.1016/s0300-9084(01)01321-9 · Cited by 345 · see citing works

Intestinal IgA production and its role in host-microbe interaction

Gutzeit, C., Magri, G., & Cerutti, A. (2014) · Immunological Reviews · doi:10.1111/imr.12189 · Cited by 332 · see citing works

New Insights in Gut Microbiota Establishment in Healthy Breast Fed Neonates

Jost, T., Lacroix, C., Braegger, C., & Chassard, C. (2012) · PLoS ONE · doi:10.1371/journal.pone.0044595 · Cited by 331 · see citing works

Innate immune lectins kill bacteria expressing blood group antigen

Stowell, S. R., Arthur, C. M., Dias-Baruffi, M., Rodrigues, L. C., Gourdine, J.-P., Heimburg-Molinaro, J., Ju, T., Molinaro, R. J., Rivera-Marrero, C., Xia, B., et al. (2010) · Nature Medicine · doi:10.1038/nm.2103 · Cited by 324 · see citing works

Patterns of Early Gut Colonization Shape Future Immune Responses of the Host

Hansen, C. H. F., Nielsen, D. S., Kverka, M., Zakostelska, Z. J., Kostovcikova, K., Hudcovic, T., Tlaskalová‐Hogenová, H., & Hansen, A. K. (2012) · PLoS ONE · doi:10.1371/journal.pone.0034043 · Cited by 310 · see citing works

Soluble factors from Lactobacillus GG activate MAPKs and induce cytoprotective heat shock proteins in intestinal epithelial cells

Tao, Y., Drabik, K., Waypa, T. S., Musch, M. W., Alverdy, J. C., Schneewind, O., Chang, E. B., & Petrof, E. O. (2005) · American Journal of Physiology-Cell Physiology · doi:10.1152/ajpcell.00131.2005 · Cited by 301 · see citing works

The role of TLRs, NLRs, and RLRs in mucosal innate immunity and homeostasis

Lavelle, E. C., Murphy, C. H., O'Neill, L. A. J., & Creagh, E. M. (2009) · Mucosal Immunology · doi:10.1038/mi.2009.124 · Cited by 291 · see citing works

Association Between Pentavalent Rotavirus Vaccine and Severe Rotavirus Diarrhea Among Children in Nicaragua

Patel, M. M. (2009) · JAMA · doi:10.1001/jama.2009.756 · Cited by 255 · see citing works

A Natural History of FUT2 Polymorphism in Humans

Ferrer-Admetlla, A., Sikora, M., Laayouni, H., Esteve‐Codina, A., Roubinet, F., Blancher, A., Calafell, F., Bertranpetit, J., & Casals, F. (2009) · Molecular Biology and Evolution · doi:10.1093/molbev/msp108 · Cited by 249 · see citing works

Spike Protein VP8* of Human Rotavirus Recognizes Histo-Blood Group Antigens in a Type-Specific Manner

Huang, P., Xia, M., Tan, M., Zhong, W., Wei, C., Wang, L., Morrow, A. L., & Jiang, X. (2012) · Journal of Virology · doi:10.1128/jvi.05507-11 · Cited by 247 · see citing works

Dietary restriction protects from age-associated DNA methylation and induces epigenetic reprogramming of lipid metabolism

Hahn, O., Grönke, S., Stubbs, T. M., Ficz, G., Hendrich, O., Krueger, F., Andrews, S., Zhang, Q., Wakelam, M. J. O., Beyer, A., et al. (2017) · Genome biology · doi:10.1186/s13059-017-1187-1 · Cited by 236 · see citing works

Vitamin A Supplementation Programs and Country-Level Evidence of Vitamin A Deficiency

Wirth, J. P., Petry, N., Tanumihardjo, S. A., Rogers, L., McLean, E., Greig, A., Garrett, G. S., Klemm, R. D. W., & Rohner, F. (2017) · Nutrients · doi:10.3390/nu9030190 · Cited by 233 · see citing works

Nutritional Keys for Intestinal Barrier Modulation

De Santis, S., Cavalcanti, E., Mastronardi, M., Jirillo, E., & Chieppa, M. (2015) · Frontiers in Immunology · doi:10.3389/fimmu.2015.00612 · Cited by 232 · see citing works

The unmet need in the elderly: How immunosenescence, CMV infection, co-morbidities and frailty are a challenge for the development of more effective influenza vaccines

McElhaney, J. E., Zhou, X., Talbot, H. K., Soethout, E., Bleackley, R. C., Granville, D. J., & Pawelec, G. (2012) · Vaccine · doi:10.1016/j.vaccine.2012.01.015 · Cited by 229 · see citing works

Modulation of humoral immune response through probiotic intake

He, F., Tuomola, E., Arvilommi, H. S., & Seppo, S. (2000) · FEMS Immunology & Medical Microbiology · doi:10.1111/j.1574-695x.2000.tb01504.x · Cited by 226 · see citing works

The effects of micronutrient deficiencies on bacterial species from the human gut microbiota

Hibberd, M. C., Wu, M., Rodionov, D. A., Li, X., Cheng, J., Griffin, N. W., Barratt, M. J., Giannone, R. J., Hettich, R. L., Osterman, A. L., et al. (2017) · Science Translational Medicine · doi:10.1126/scitranslmed.aal4069 · Cited by 221 · see citing works

Proteus spp. as Putative Gastrointestinal Pathogens

Hamilton, A. L., Kamm, M. A., Ng, S. C., & Morrison, M. (2018) · Clinical Microbiology Reviews · doi:10.1128/cmr.00085-17 · Cited by 221 · see citing works

Diet and the epigenetic (re)programming of phenotypic differences in behavior

McGowan, P. O., Meaney, M. J., & Moshe Szyf, A. (2008) · Brain Research · doi:10.1016/j.brainres.2008.07.074 · Cited by 212 · see citing works

Systems vaccinology: Probing humanity’s diverse immune systems with vaccines

Pulendran, B. (2014) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1400476111 · Cited by 208 · see citing works

The Virome in Host Health and Disease

Cadwell, K. (2015) · Immunity · doi:10.1016/j.immuni.2015.05.003 · Cited by 202 · see citing works

Comparison of probiotic lactobacilli and bifidobacteria effects, immune responses and rotavirus vaccines and infection in different host species

Vlasova, A. N., Kandasamy, S., Chattha, K. S., Rajashekara, G., & Saif, L. J. (2016) · Veterinary Immunology and Immunopathology · doi:10.1016/j.vetimm.2016.01.003 · Cited by 197 · see citing works

Histo-Blood Group Antigen-Like Substances of Human Enteric Bacteria as Specific Adsorbents for Human Noroviruses

Miura, T., Sano, D., Suenaga, A., Yoshimura, T., Fuzawa, M., Nakagomi, T., Nakagomi, O., & Okabe, S. (2013) · Journal of Virology · doi:10.1128/jvi.01060-13 · Cited by 193 · see citing works

Probiotic bacteria stimulate virus-specific neutralizing antibodies following a booster polio vaccination

de Vrese, M., Rautenberg, P., Laue, C., Koopmans, M., Herremans, T., & Schrezenmeir, J. (2005) · European Journal of Nutrition · doi:10.1007/s00394-004-0541-8 · Cited by 190 · see citing works

Effects of seven potential probiotic strains on specific immune responses in healthy adults: a double-blind, randomized, controlled trial

Paineau, D., Carcano, D., Leyer, G., Darquy, S., Alyanakian, M., Simoneau, G., Bergmann, J., Brassart, D., Bornet, F. R. J., & Ouwehand, A. C. (2008) · FEMS Immunology & Medical Microbiology · doi:10.1111/j.1574-695x.2008.00413.x · Cited by 187 · see citing works

Rotavirus VP8*: Phylogeny, Host Range, and Interaction with Histo-Blood Group Antigens

Liu, Y., Huang, P., Tan, M., Liu, Y., Biesiada, J., Meller, J., Castello, A. A., Jiang, B., & Jiang, X. (2012) · Journal of Virology · doi:10.1128/jvi.00979-12 · Cited by 183 · see citing works

Lactobacillus rhamnosus blocks inflammatory signaling in vivo via reactive oxygen species generation

Lin, P. W., Myers, L., Ray, L., Song, S., Nasr, T. R., Berardinelli, A., Kundu, K., Murthy, N., Hansen, J. M., & Neish, A. S. (2009) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2009.07.033 · Cited by 183 · see citing works

Normalizing Microbiota-Induced Retinoic Acid Deficiency Stimulates Protective CD8 + T Cell-Mediated Immunity in Colorectal Cancer

Bhattacharya, N., Yuan, R. T., Prestwood, T. R., Penny, H. L., DiMaio, M. A., Reticker-Flynn, N. E., Krois, C. R., Kenkel, J. A., Pham, T. D., Carmi, Y., et al. (2016) · Immunity · doi:10.1016/j.immuni.2016.08.008 · Cited by 165 · see citing works

Retinoic acid induces homing of protective T and B cells to the gut after subcutaneous immunization in mice

Hammerschmidt, S. I., Friedrichsen, M., Boelter, J., Łyszkiewicz, M., Kremmer, E., Pabst, O., & Förster, R. (2011) · Journal of Clinical Investigation · doi:10.1172/jci44262 · Cited by 158 · see citing works

Retinoic acid controls the homeostasis of pre-cDC–derived splenic and intestinal dendritic cells

Klebanoff, C. A., Spencer, S. P., Torabi‐Parizi, P., Grainger, J. R., Roychoudhuri, R., Ji, Y., Sukumar, M., Muranski, P. J., Scott, C. D., Hall, J. A., et al. (2013) · The Journal of Experimental Medicine · doi:10.1084/jem.20122508 · Cited by 157 · see citing works

Influence of the microbiota on vaccine effectiveness

Valdez, Y., Brown, E., & Finlay, B. B. (2014) · Trends in Immunology · doi:10.1016/j.it.2014.07.003 · Cited by 144 · see citing works

Association between the ABO blood group and the human intestinal microbiota composition

Mäkivuokko, H., Lahtinen, S. J., Wacklin, P., Tuovinen, E. A., Tenkanen, H., Nikkilä, J., Björklund, M., Aranko, K., Ouwehand, A. C., & Mättö, J. (2012) · BMC Microbiology · doi:10.1186/1471-2180-12-94 · Cited by 138 · see citing works

Effect of Antibiotic-Mediated Microbiome Modulation on Rotavirus Vaccine Immunogenicity: A Human, Randomized-Control Proof-of-Concept Trial

Harris, V., Haak, B. W., Handley, S. A., Jiang, B., Velásquez, D. E., Hykes, B. L., Droit, L., Berbers, G. A. M., Kemper, E. M., van Leeuwen, E. M. M., et al. (2018) · Cell Host & Microbe · doi:10.1016/j.chom.2018.07.005 · Cited by 129 · see citing works

Zinc Competition among the Intestinal Microbiota

Gielda, L. M., & DiRita, V. J. (2012) · mBio · doi:10.1128/mbio.00171-12 · Cited by 121 · see citing works

Differential Effects of Escherichia coli Nissle and Lactobacillus rhamnosus Strain GG on Human Rotavirus Binding, Infection, and B Cell Immunity

Kandasamy, S., Vlasova, A. N., Fischer, D. D., Kumar, A., Chattha, K. S., Rauf, A., Shao, L., Langel, S. N., Rajashekara, G., & Saif, L. J. (2016) · The Journal of Immunology · doi:10.4049/jimmunol.1501705 · Cited by 113 · see citing works

The Intestinal Flora Is Required to Support Antibody Responses to Systemic Immunization in Infant and Germ Free Mice

Lamousé-Smith, E. S. N., Tzeng, A., & Starnbach, M. N. (2011) · PLoS ONE · doi:10.1371/journal.pone.0027662 · Cited by 107 · see citing works

Effect of probiotics on vaccine antibody responses in infancy – a randomized placebo‐controlled double‐blind trial

Kukkonen, A. K., Nieminen, T., Poussa, T. A., Savilahti, E., & Kuitunen, M. (2006) · Pediatric Allergy and Immunology · doi:10.1111/j.1399-3038.2006.00420.x · Cited by 106 · see citing works

Effects of feeding probiotics during weaning on infections and antibody responses to diphtheria, tetanus and Hib vaccines

West, C. E., Gothefors, L., Granström, M., Käyhty, H. M., Hammarström, M., & Hernell, O. (2008) · Pediatric Allergy and Immunology · doi:10.1111/j.1399-3038.2007.00583.x · Cited by 105 · see citing works

Interactions between intestinal pathogens, enteropathy and malnutrition in developing countries

Prendergast, A. J., & Kelly, P. M. (2016) · Current Opinion in Infectious Diseases · doi:10.1097/qco.0000000000000261 · Cited by 105 · see citing works

The “Performance of Rotavirus and Oral Polio Vaccines in Developing Countries” (PROVIDE) Study: Description of Methods of an Interventional Study Designed to Explore Complex Biologic Problems

Kirkpatrick, B. D., Colgate, E. R., Mychaleckyj, J. C., Haque, R., Dickson, D. M., Carmolli, M. P., Nayak, U., Taniuchi, M., Naylor, C., Qadri, F., et al. (2015) · American Journal of Tropical Medicine and Hygiene · doi:10.4269/ajtmh.14-0518 · Cited by 105 · see citing works

The Virome and Its Major Component, Anellovirus, a Convoluted System Molding Human Immune Defenses and Possibly Affecting the Development of Asthma and Respiratory Diseases in Childhood

Freer, G., Maggi, F., Pifferi, M., Cicco, M. D., Peroni, D. G., & Pistello, M. (2018) · Frontiers in Microbiology · doi:10.3389/fmicb.2018.00686 · Cited by 105 · see citing works

Control of antiviral immunity by pattern recognition and the microbiome

Pang, I. K., & Iwasaki, A. (2011) · Immunological Reviews · doi:10.1111/j.1600-065x.2011.01073.x · Cited by 103 · see citing works

Rotavirus vaccines: Successes and challenges

Glass, R. I., Parashar, U. D., Patel, M. M., Gentsch, J. R., & Jiang, B. (2013) · Journal of Infection · doi:10.1016/j.jinf.2013.09.010 · Cited by 101 · see citing works

Lactobacilli and Bifidobacteria Promote Immune Homeostasis by Modulating Innate Immune Responses to Human Rotavirus in Neonatal Gnotobiotic Pigs

Vlasova, A. N., Chattha, K. S., Kandasamy, S., Liu, Z., Esseili, M. A., Shao, L., Rajashekara, G., & Saif, L. J. (2013) · PLoS ONE · doi:10.1371/journal.pone.0076962 · Cited by 99 · see citing works

Temporal stability of the mouse gut microbiota in relation to innate and adaptive immunity

Dimitriu, P. A., Boyce, G. K., Samarakoon, A., Hartmann, M., Johnson, P., & Mohn, W. W. (2012) · Environmental Microbiology Reports · doi:10.1111/j.1758-2229.2012.00393.x · Cited by 95 · see citing works

Antibody Repertoire Development in Fetal and Neonatal Piglets. VIII. Colonization Is Required for Newborn Piglets to Make Serum Antibodies to T-Dependent and Type 2 T-Independent Antigens

Butler, J. E., Weber, P., Šinkora, M., Baker, D., Schoenherr, A., Mayer, B., & Francis, D. H. (2002) · The Journal of Immunology · doi:10.4049/jimmunol.169.12.6822 · Cited by 94 · see citing works

Effect of breastfeeding on immunogenicity of oral live-attenuated human rotavirus vaccine: a randomized trial in HIV-uninfected infants in Soweto, South Africa

Groome, M. J., Moon, S.-S., Velásquez, D. E., Jones, S., Koen, A. L., van Niekerk, N., Jiang, B., Parashar, U. D., & Madhi, S. A. (2014) · Bulletin of the World Health Organization · doi:10.2471/blt.13.128066 · Cited by 92 · see citing works

Normal Human Serum Contains Natural Antibodies Reactive With Autologous ABO Blood Group Antigens

Spalter, S. H., Kaveri, S. V., Bonnin, E., Mani, J. C., Cartron, J., & Kazatchkine, M. D. (1999) · Blood · doi:10.1182/blood.v93.12.4418 · Cited by 87 · see citing works

Host–microbe relationships in inflammatory bowel disease detected by bacterial and metaproteomic analysis of the mucosal–luminal interface

Presley, L. L., Ye, J., Li, X., LeBlanc, J. F., Zhang, Z., Ruegger, P. M., Allard, J., McGovern, D. P. B., Ippoliti, A., Roth, B. E., et al. (2011) · Inflammatory Bowel Diseases · doi:10.1002/ibd.21793 · Cited by 85 · see citing works

Effect of withholding breastfeeding on the immune response to a live oral rotavirus vaccine in North Indian infants

Rongsen‐Chandola, T., Strand, T. A., Goyal, N. P., Flem, E., Rathore, S. S., Arya, A., Winje, B. A., Lazarus, R. P., Shanmugasundaram, E., Babji, S., et al. (2014) · Vaccine · doi:10.1016/j.vaccine.2014.04.078 · Cited by 84 · see citing works

Divergent Immunomodulating Effects of Probiotics on T Cell Responses to Oral Attenuated Human Rotavirus Vaccine and Virulent Human Rotavirus Infection in a Neonatal Gnotobiotic Piglet Disease Model

Chattha, K. S., Vlasova, A. N., Kandasamy, S., Rajashekara, G., & Saif, L. J. (2013) · The Journal of Immunology · doi:10.4049/jimmunol.1300678 · Cited by 83 · see citing works

Exploring the role of environmental enteropathy in malnutrition, infant development and oral vaccine response

Gilmartin, A. A., & Petri, W. A. (2015) · Philosophical Transactions of the Royal Society B Biological Sciences · doi:10.1098/rstb.2014.0143 · Cited by 83 · see citing works

Adjuvant Probiotics and the Intestinal Microbiome: Enhancing Vaccines and Immunotherapy Outcomes

Vitetta, L., Saltzman, E., Thomsen, M., Nikov, T., & Hall, S. (2017) · Vaccines · doi:10.3390/vaccines5040050 · Cited by 83 · see citing works

Should the Human Microbiome Be Considered When Developing Vaccines?

Ferreira, R. B. R., Antunes, L. C. M., & Finlay, B. B. (2010) · PLoS Pathogens · doi:10.1371/journal.ppat.1001190 · Cited by 82 · see citing works

Histo-blood group antigens as receptors for rotavirus, new understanding on rotavirus epidemiology and vaccine strategy

Jiang, X., Liu, Y., & Tan, M. (2017) · Emerging Microbes &Infections · doi:10.1038/emi.2017.30 · Cited by 82 · see citing works

Effect of probiotic supplementation in the first 6 months of life on specific antibody responses to infant Hepatitis B vaccination

Soh, S. E., Ong, D. Q. R., Gerez, I., Zhang, X., Chollate, P., Shek, L. P.-C., Lee, B. W., & Aw, M. (2010) · Vaccine · doi:10.1016/j.vaccine.2010.01.020 · Cited by 78 · see citing works

Histo–Blood Group Antigen Phenotype Determines Susceptibility to Genotype-Specific Rotavirus Infections and Impacts Measures of Rotavirus Vaccine Efficacy

Lee, B., Dickson, D. M., deCamp, A. C., Colgate, E. R., Diehl, S. A., Uddin, M. I., Sharmin, S., Islam, S., Bhuiyan, T. R., Alam, M., et al. (2018) · The Journal of Infectious Diseases · doi:10.1093/infdis/jiy054 · Cited by 77 · see citing works

Taxa of the nasal microbiome are associated with influenza-specific IgA response to live attenuated influenza vaccine

Salk, H. M., Simon, W. L., Lambert, N. D., Kennedy, R. B., Grill, D. E., Kabat, B. F., & Poland, G. A. (2016) · PLoS ONE · doi:10.1371/journal.pone.0162803 · Cited by 75 · cited 1× · see citing works

Lactobacilli binding human A-antigen expressed in intestinal mucosa

Uchida, H., Kinoshita, H., Kawai, Y., Kitazawa, H., Miura, K., Shiiba, K., Horii, A., Kimura, K., Taketomo, N., Oda, M., et al. (2006) · Research in Microbiology · doi:10.1016/j.resmic.2006.03.001 · Cited by 74 · see citing works

Influence of Enteric Infections on Response to Oral Poliovirus Vaccine: A Systematic Review and Meta-analysis

Parker, E. P. K., Kampmann, B., Kang, G., & Grassly, N. C. (2014) · The Journal of Infectious Diseases · doi:10.1093/infdis/jiu182 · Cited by 74 · see citing works

Impaired mucosal antibody response to cholera toxin in vitamin A-deficient rats immunized with oral cholera vaccine

Wiedermann, U., HANSON, L. Å., Holmgren, J. R., Kahu, H., & Dahlgren, U. I. (1993) · Infection and Immunity · doi:10.1128/iai.61.9.3952-3957.1993 · Cited by 74 · see citing works

Probiotic Lactobacillus rhamnosus GG Enhanced Th1 Cellular Immunity but Did Not Affect Antibody Responses in a Human Gut Microbiota Transplanted Neonatal Gnotobiotic Pig Model

Wen, K., Tin, C. M., Wang, H., Yang, X., Li, G., Giri-Rachman, E. A., Kocher, J., Bui, T., Clark‐Deener, S., & Yuan, L. (2014) · PLoS ONE · doi:10.1371/journal.pone.0094504 · Cited by 70 · see citing works

Probiotics, antibiotics and the immune responses to vaccines

Praharaj, I., John, S. M., Bandyopadhyay, R., & Kang, G. (2015) · Philosophical Transactions of the Royal Society B Biological Sciences · doi:10.1098/rstb.2014.0144 · Cited by 69 · see citing works

Modeling human enteric dysbiosis and rotavirus immunity in gnotobiotic pigs

Twitchell, E. L., Tin, C. M., Wen, K., Zhang, H., Becker‐Dreps, S., Azcárate-Peril, M. A., Vilchez, S., Li, G., Ramesh, A. K., Weiss, M., et al. (2016) · Gut Pathogens · doi:10.1186/s13099-016-0136-y · Cited by 68 · see citing works

The Lewis A phenotype is a restriction factor for Rotateq and Rotarix vaccine-take in Nicaraguan children

Bucardo, F., Nordgren, J., Reyes, Y. I., González, F., Sharma, S., & Svensson, L. (2018) · Scientific Reports · doi:10.1038/s41598-018-19718-y · Cited by 65 · see citing works

Prenatally Acquired Vitamin A Deficiency Alters Innate Immune Responses to Human Rotavirus in a Gnotobiotic Pig Model

Vlasova, A. N., Chattha, K. S., Kandasamy, S., Siegismund, C. S., & Saif, L. J. (2013) · The Journal of Immunology · doi:10.4049/jimmunol.1203575 · Cited by 64 · see citing works

Hepatitis B vaccine in celiac disease: Yesterday, today and tomorrow

Vitaliti, G. (2013) · World Journal of Gastroenterology · doi:10.3748/wjg.v19.i6.838 · Cited by 62 · see citing works

Vaccine adjuvant properties of probiotic bacteria.

Licciardi, P. V., & Tang, M. L. K. (2011) · PubMed · Cited by 58 · see citing works

Relationships between gastrointestinal microbiota and blood group antigens

Gampa, A., Engen, P. A., Shobar, R., & Mutlu, E. (2017) · Physiological Genomics · doi:10.1152/physiolgenomics.00043.2017 · Cited by 56 · see citing works

Effects of Child and Maternal Histo-Blood Group Antigen Status on Symptomatic and Asymptomatic Enteric Infections in Early Childhood

Colston, J. M., François, R., Pisanic, N., Yori, P. P., McCormick, B., Olórtegui, M. P., Gazi, M. A., Svensen, E., Ahmed, M. M. M., Mduma, E. R., et al. (2019) · The Journal of Infectious Diseases · doi:10.1093/infdis/jiz072 · Cited by 56 · see citing works

Lactobacillus rhamnosus GG modulates innate signaling pathway and cytokine responses to rotavirus vaccine in intestinal mononuclear cells of gnotobiotic pigs transplanted with human gut microbiota

Wang, H., Gao, K., Wen, K., Allen, I. C., Li, G., Zhang, W., Kocher, J., Yang, X., Giri-Rachman, E. A., Li, G., et al. (2016) · BMC Microbiology · doi:10.1186/s12866-016-0727-2 · Cited by 54 · see citing works

Prenatal vitamin A deficiency impairs adaptive immune responses to pentavalent rotavirus vaccine (RotaTeq®) in a neonatal gnotobiotic pig model

Kandasamy, S., Chattha, K. S., Vlasova, A. N., & Saif, L. J. (2014) · Vaccine · doi:10.1016/j.vaccine.2013.12.039 · Cited by 51 · see citing works

Immune systems in developed and developing countries; implications for the design of vaccines that will work where BCG does not

Rook, G. A. W., Dheda, K. U. J., & Zumla, A. I. (2006) · Tuberculosis · doi:10.1016/j.tube.2006.01.018 · Cited by 51 · see citing works

Response to Hepatitis B Vaccination in Patients with Celiac Disease

Ahıshalı, E., Boztaş, G., Akyüz, F., İbrişim, D., Poturoğlu, Ş., Pınarbaşı, B., Özdil, S., & Mungan, Z. A. (2007) · Digestive Diseases and Sciences · doi:10.1007/s10620-007-0128-3 · Cited by 47 · see citing works

Protein Malnutrition Modifies Innate Immunity and Gene Expression by Intestinal Epithelial Cells and Human Rotavirus Infection in Neonatal Gnotobiotic Pigs

Vlasova, A. N., Paim, F. C., Kandasamy, S., Alhamo, M. A., Fischer, D. D., Langel, S. N., Deblais, L., Kumar, A., Chepngeno, J., Shao, L., et al. (2017) · mSphere · doi:10.1128/msphere.00046-17 · Cited by 44 · see citing works

Escherichia coli Nissle 1917 protects gnotobiotic pigs against human rotavirus by modulating pDC and NK‐cell responses

Vlasova, A. N., Shao, L., Kandasamy, S., Fischer, D. D., Rauf, A., Langel, S. N., Chattha, K. S., Kumar, A., Huang, H., Rajashekara, G., et al. (2016) · European Journal of Immunology · doi:10.1002/eji.201646498 · Cited by 42 · see citing works

ABO histo-blood group might modulate predisposition to Crohn's disease and affect disease behavior

Forni, D., Cleynen, I., Ferrante, M., Cassinotti, A., Cagliani, R., Ardizzone, S., Vermeire, S., Fichera, M., Lombardini, M., Maconi, G., et al. (2013) · Journal of Crohn s and Colitis · doi:10.1016/j.crohns.2013.10.014 · Cited by 40 · see citing works

Protein deficiency reduces efficacy of oral attenuated human rotavirus vaccine in a human infant fecal microbiota transplanted gnotobiotic pig model

Miyazaki, A., Kandasamy, S., Michael, H., Langel, S. N., Paim, F. C., Chepngeno, J., Alhamo, M. A., Fischer, D. D., Huang, H., Srivastava, V., et al. (2018) · Vaccine · doi:10.1016/j.vaccine.2018.09.008 · Cited by 40 · see citing works

Influence of the microbiome on response to vaccination

Jamieson, A. M. (2015) · Human Vaccines & Immunotherapeutics · doi:10.1080/21645515.2015.1022699 · Cited by 38 · see citing works

Lactobacillus rhamnosus GG Dosage Affects the Adjuvanticity and Protection Against Rotavirus Diarrhea in Gnotobiotic Pigs

Wen, K., Liu, F., Li, G., Bai, M., Kocher, J., Yang, X., Wang, H., Clark‐Deener, S., & Yuan, L. (2015) · Journal of Pediatric Gastroenterology and Nutrition · doi:10.1097/mpg.0000000000000694 · Cited by 36 · see citing works

Probiotics and colostrum/milk differentially affect neonatal humoral immune responses to oral rotavirus vaccine

Chattha, K. S., Vlasova, A. N., Kandasamy, S., Esseili, M. A., Siegismund, C. S., Rajashekara, G., & Saif, L. J. (2013) · Vaccine · doi:10.1016/j.vaccine.2013.02.020 · Cited by 36 · see citing works

Lactic Acid Bacteria (LAB) Bind to Human B- or H-Antigens Expressed on Intestinal Mucosa

Uchida, H., Kawai, Y., KINOSHITA, H., Kitazawa, H., Miura, K., Shiiba, K., Horii, A., Kimura, K., Taketomo, N., Oda, M., et al. (2006) · Bioscience Biotechnology and Biochemistry · doi:10.1271/bbb.60407 · Cited by 35 · see citing works

In vivo gut transcriptome responses toLactobacillus rhamnosusGG andLactobacillus acidophilusin neonatal gnotobiotic piglets

Kumar, A., Vlasova, A. N., Liu, Z., Chattha, K. S., Kandasamy, S., Esseili, M. A., Zhang, X., Rajashekara, G., & Saif, L. J. (2014) · Gut Microbes · doi:10.4161/gmic.27877 · Cited by 34 · see citing works

The Effect of Human Immunodeficiency Virus and Cytomegalovirus Infection on Infant Responses to Vaccines: A Review

Falconer, O., Newell, M., & Jones, C. E. (2018) · Frontiers in Immunology · doi:10.3389/fimmu.2018.00328 · Cited by 32 · see citing works

Diverse microbial exposure – Consequences for vaccine development

Björkstén, B. (2011) · Vaccine · doi:10.1016/j.vaccine.2011.10.074 · Cited by 30 · see citing works

Gestational Zinc Deficiency Impairs Humoral and Cellular Immune Responses to Hepatitis B Vaccination in Offspring Mice

Zhao, N., Wang, X., Zhang, Y., Gu, Q., Huang, F., Zheng, W., & Li, Z. (2013) · PLoS ONE · doi:10.1371/journal.pone.0073461 · Cited by 29 · see citing works

Association of Histo–Blood Group Antigens with Susceptibility to Norovirus Infection May Be Strain‐Specific Rather than Genogroup Dependent

Tan, M., & Jiang, X. (2008) · The Journal of Infectious Diseases · doi:10.1086/589810 · Cited by 28 · see citing works

ABO blood grouping in Egyptian children with rotavirus gastroenteritis

Elnady, H. G., Samie, O. M. A., Saleh, M., Sherif, L. S., Abdalmoneam, N., Kholoussi, N. M., Kholoussi, S., & Taweel, A. E. (2017) · Gastroenterology Review · doi:10.5114/pg.2017.70469 · Cited by 26 · see citing works

Tissue-specific mRNA expression profiles of porcine Toll-like receptors at different ages in germ-free and conventional pigs

Shao, L., Fischer, D. D., Kandasamy, S., Saif, L. J., & Vlasova, A. N. (2016) · Veterinary Immunology and Immunopathology · doi:10.1016/j.vetimm.2016.01.008 · Cited by 24 · see citing works

Unique Transcompartmental Bridge: Antigen-Presenting Cells Sampling across Endothelial and Mucosal Barriers

Allen, F., Tong, A. A., & Huang, A. Y.-C. (2016) · Frontiers in Immunology · doi:10.3389/fimmu.2016.00231 · Cited by 14 · see citing works

Probiotics Mechanism of Action on Immune Cells and Beneficial Effects on Human Health

Mazziotta, C., Tognon, M., Martini, F., Torreggiani, E., & Rotondo, J. C. (2023) · Cells · doi:10.3390/cells12010184 · Cited by 889 · see citing works

Individual risk management strategy and potential therapeutic options for the COVID-19 pandemic

Gasmi, A., Noor, S., Tippairote, T., Dadar, M., Menzel, A., & Bjørklund, G. (2020) · Clinical Immunology · doi:10.1016/j.clim.2020.108409 · Cited by 310 · see citing works

Viral Infections, the Microbiome, and Probiotics

Harper, A., Vijayakumar, V., Ouwehand, A. C., ter Haar, J., Obis, D., Espadaler, J., Binda, S., Desiraju, S., & Day, R. (2021) · Frontiers in Cellular and Infection Microbiology · doi:10.3389/fcimb.2020.596166 · Cited by 177 · see citing works

Prevotella in Pigs: The Positive and Negative Associations with Production and Health

Amat, S., Lantz, H. L., Munyaka, P. M., & Willing, B. P. (2020) · Microorganisms · doi:10.3390/microorganisms8101584 · Cited by 141 · see citing works

Rotaviruses: From Pathogenesis to Disease Control—A Critical Review

Omatola, C. A., & Olaniran, A. O. (2022) · Viruses · doi:10.3390/v14050875 · Cited by 111 · see citing works

Gut Microbiota Diversity and C-Reactive Protein Are Predictors of Disease Severity in COVID-19 Patients

Moreira-Rosário, A., Marques, C., Pinheiro, H., Araújo, J. R., Ribeiro, P., Rocha, R., Barreiros-Mota, I., Pestana, D., Ribeiro, R., Pereira, A. M., et al. (2021) · Frontiers in Microbiology · doi:10.3389/fmicb.2021.705020 · Cited by 100 · see citing works

Microbiome Dynamics: A Paradigm Shift in Combatting Infectious Diseases

Kamel, M. S., Aleya, S., Alsubih, M., & Aleya, L. (2024) · Journal of Personalized Medicine · doi:10.3390/jpm14020217 · Cited by 96 · see citing works

Covid-19 and blood groups: ABO antibody levels may also matter

Deleers, M., Breiman, A., Daubie, V., Maggetto, C., Barreau, I., Besse, T., Clemenceau, B., Ruvoën‐Clouet, N., Fils, J., Maillart, E., et al. (2020) · International Journal of Infectious Diseases · doi:10.1016/j.ijid.2020.12.025 · Cited by 80 · see citing works

Modulation of gut‐microbiota through probiotics and dietary interventions to improve host health

Dasriya, V. L., Samtiya, M., Ranveer, S. A., Dhillon, H. S., Devi, N., Sharma, V., Nikam, P., Puniya, M., Chaudhary, P., Chaudhary, V., et al. (2024) · Journal of the Science of Food and Agriculture · doi:10.1002/jsfa.13370 · Cited by 80 · see citing works

Advances in Oral Subunit Vaccine Design

der Weken, H. V., Cox, E., & Devriendt, B. (2020) · Vaccines · doi:10.3390/vaccines9010001 · Cited by 78 · see citing works

Vaccine- and natural infection-induced mechanisms that could modulate vaccine safety

Kostoff, R. N., Kanduc, D., Porter, A. L., Shoenfeld, Y., Călina, D. C., Briggs, M. B., Spandidos, D. A., & Tsatsakis, A. M. (2020) · Toxicology Reports · doi:10.1016/j.toxrep.2020.10.016 · Cited by 61 · see citing works

Rotavirus research: 2014–2020

Caddy, S., Papa, G., Borodavka, A., & Desselberger, U. (2021) · Virus Research · doi:10.1016/j.virusres.2021.198499 · Cited by 61 · see citing works

COVID-19: An overview and a clinical update

Krishnan, A., Hamilton, J. P., Alqahtani, S. A., & Woreta, T. A. (2020) · World Journal of Clinical Cases · doi:10.12998/wjcc.v9.i1.8 · Cited by 59 · see citing works

The early-life gut microbiome and vaccine efficacy

Jordan, A., Carding, S. R., & Hall, L. J. (2022) · The Lancet Microbe · doi:10.1016/s2666-5247(22)00185-9 · Cited by 58 · see citing works

Functional food: complementary to fight against COVID-19

Farzana, M., Shahriar, S., Jeba, F. R., Tabassum, T., Araf, Y., Ullah, M. A., Tasnim, J., Chakraborty, A., Naima, T. A., Marma, K. K. S., et al. (2022) · Beni-Suef University Journal of Basic and Applied Sciences · doi:10.1186/s43088-022-00217-z · Cited by 45 · see citing works

The microbiota-mediated dietary and nutritional interventions for COVID-19

Gasmi, A., Tippairote, T., Mujawdiya, P. K., Peana, M., Menzel, A., Dadar, M., Gasmi Benahmed, A., & Bjørklund, G. (2021) · Clinical Immunology · doi:10.1016/j.clim.2021.108725 · Cited by 42 · see citing works

The Interplay between the Host Microbiome and Pathogenic Viral Infections

González, R., & Elena, S. F. (2021) · mBio · doi:10.1128/mbio.02496-21 · Cited by 42 · see citing works

Challenges for Clinical Development of Vaccines for Prevention of Hospital-Acquired Bacterial Infections

Bekeredjian‐Ding, I. (2020) · Frontiers in Immunology · doi:10.3389/fimmu.2020.01755 · Cited by 40 · see citing works

Neonatal Immune System Ontogeny: The Role of Maternal Microbiota and Associated Factors. How Might the Non-Human Primate Model Enlighten the Path?

Nunez, N., Réot, L., & Menu, E. (2021) · Vaccines · doi:10.3390/vaccines9060584 · Cited by 37 · see citing works

Immune modulatory capacity of probiotic lactic acid bacteria and applications in vaccine development

Mojgani, N., Shahali, Y., & Dadar, M. (2020) · Beneficial Microbes · doi:10.3920/bm2019.0121 · Cited by 35 · see citing works

Characterization of markers, functional properties, and microbiome composition in human gut-derived bacterial extracellular vesicles

Li, C.-C., Hsu, W.-F., Chiang, P.-C., Kuo, M., Wo, A. M., & Tseng, Y. J. (2023) · Gut Microbes · doi:10.1080/19490976.2023.2288200 · Cited by 33 · see citing works

The Interplay between Immunosenescence and Microbiota in the Efficacy of Vaccines

Cianci, R., Franza, L., Massaro, M. G., Borriello, R., Vito, F., & Gambassi, G. (2020) · Vaccines · doi:10.3390/vaccines8040636 · Cited by 31 · see citing works

Gut microbiome, Vitamin D, ACE2 interactions are critical factors in immune-senescence and inflammaging: key for vaccine response and severity of COVID-19 infection

Shenoy, S. (2021) · Inflammation Research · doi:10.1007/s00011-021-01510-w · Cited by 31 · see citing works

Effects of the Antimicrobial Peptide Mastoparan X on the Performance, Permeability and Microbiota Populations of Broiler Chickens

Zhu, C., Bai, Y., Xia, X., Zhang, M., Wu, X., Wu, Y., Bai, Y., Liu, S., Zhang, G., Hu, J., et al. (2022) · Animals · doi:10.3390/ani12243462 · Cited by 27 · see citing works

Gut Microbiota and Postbiotic Metabolites: Biotic Intervention for Enhancing Vaccine Responses and Personalized Medicine for Disease Prevention

Mojgani, N., Ashique, S., Moradi, M., Bagheri, M., Garg, A., Kaushik, M., Hussain, M. S., Yasmin, S., & Ansari, M. Y. (2025) · Probiotics and Antimicrobial Proteins · doi:10.1007/s12602-025-10477-7 · Cited by 30 · see citing works

Dupilumab therapy improves gut microbiome dysbiosis and tryptophan metabolism in Chinese patients with atopic dermatitis

Yang, J., Li, D., Sun, S., Liu, D., Wang, Y., Liu, X., Zhou, B., Nie, W., Li, L., Wang, Y., et al. (2024) · International Immunopharmacology · doi:10.1016/j.intimp.2024.111867 · Cited by 25 · see citing works

Oral Immunization with Escherichia coli Nissle 1917 Expressing SARS-CoV-2 Spike Protein Induces Mucosal and Systemic Antibody Responses in Mice

Sarnelli, G., Re, A., Pesce, M., Lu, J., Esposito, G., Sanseverino, W., Corpetti, C., Franzin, S. B., Seguella, L., Palenca, I., et al. (2023) · Biomolecules · doi:10.3390/biom13030569 · Cited by 23 · see citing works

Serological Humoral Immunity Following Natural Infection of Children with High Burden Gastrointestinal Viruses

Zweigart, M. R., Becker‐Dreps, S., Bucardo, F., González, F., Baric, R. S., & Lindesmith, L. C. (2021) · Viruses · doi:10.3390/v13102033 · Cited by 21 · see citing works

Intestinal Microbiota and Its Effect on Vaccine-Induced Immune Amplification and Tolerance

Liu, Y., Zhou, J., Yang, Y., Chen, X., Chen, L., & Wu, Y. (2024) · Vaccines · doi:10.3390/vaccines12080868 · Cited by 19 · see citing works

Effect of antibiotic treatment on microbial composition and expression of antimicrobial peptides and cytokines in the chick cecum

TERADA, T., Nii, T., Isobe, N., & Yoshimura, Y. (2020) · Poultry Science · doi:10.1016/j.psj.2020.03.016 · Cited by 18 · see citing works

Rotavirus vaccines performance: dynamic interdependence of host, pathogen and environment

Saha, D., Ota, M. O. C., Pereira, P., Buchy, P., & Badur, S. (2021) · Expert Review of Vaccines · doi:10.1080/14760584.2021.1951247 · Cited by 18 · see citing works

Relationship between Papillomavirus vaccine, vaginal microbiome, and local cytokine response: an exploratory research

Giraldo, P. C., Sanches, J. M., Sparvoli, L. G., do Amaral, R. L. G., Migliorini, I., Gil, C. D., Taddei, C. R., Witkin, S. S., & Discacciati, M. G. (2021) · Brazilian Journal of Microbiology · doi:10.1007/s42770-021-00616-x · Cited by 16 · see citing works

Human Respiratory and Gut Microbiomes—Do They Really Contribute to Respiratory Health?

Durack, J., & Christophersen, C. T. (2020) · Frontiers in Pediatrics · doi:10.3389/fped.2020.00528 · Cited by 16 · see citing works

Impact of Transcriptome and Gut Microbiome on the Response of HIV-1 Infected Individuals to a Dendritic Cell-Based HIV Therapeutic Vaccine

Pastor-Ibáñez, R., Díez‐Fuertes, F., Sánchez‐Palomino, S., Alcamı́, J., Plana, M., Torrents, D., Leal, L., & García, F. (2021) · Vaccines · doi:10.3390/vaccines9070694 · Cited by 13 · see citing works

Gut microbiota as a regulator of vaccine efficacy: implications for personalized vaccination

Lu, Q., Feng, Y., Wang, H., Zhu, K., Teng, L., Yue, M., & Li, Y. (2025) · Gut Microbes · doi:10.1080/19490976.2025.2563709 · Cited by 12 · see citing works

Combined use of lactic-acid-producing bacteria as probiotics and rotavirus vaccine candidates expressing virus-specific proteins

Afchangi, A., Latifi, T., Jalilvand, S., Marashi, S. M., & Shoja, Z. (2021) · Archives of Virology · doi:10.1007/s00705-021-04964-9 · Cited by 11 · see citing works

Gut microbiota and synbiotic foods: Unveiling the relationship in COVID ‐19 perspective

Akram, N., Saeed, F., Afzaal, M., Shah, Y. A., Qamar, A., Faisal, Z., Ghani, S., Ateeq, H., Akhtar, M. N., Tufail, T., et al. (2023) · Food Science & Nutrition · doi:10.1002/fsn3.3162 · Cited by 9 · see citing works

Investigating the gut bacteria structure and function of hibernating bats through 16S rRNA high-throughput sequencing and culturomics

Zhou, J., Liu, Y., Gu, T., Zhou, J., Chen, F., & Li, S. (2025) · mSystems · doi:10.1128/msystems.01463-24 · Cited by 9 · see citing works

Significance of the Gut Microbiome for Viral Diarrheal and Extra-Intestinal Diseases

Desselberger, U. (2021) · Viruses · doi:10.3390/v13081601 · Cited by 9 · see citing works

Abundance of Lactobacillus in porcine gut microbiota is closely related to immune response following PRRSV immunization

Zhang, H., Ma, W., Sun, Z., Zhu, C., Werid, G. M., Ibrahim, Y. M., Zhang, W., Pan, Y., Shi, D., Chen, H., et al. (2021) · Veterinary Microbiology · doi:10.1016/j.vetmic.2021.109134 · Cited by 8 · see citing works

A review on the immunomodulatory properties of functional nutraceuticals as dietary interventions for children to combat COVID-19 related infections

Soni, S., & Paari, K. A. (2023) · Food Production Processing and Nutrition · doi:10.1186/s43014-023-00133-4 · Cited by 8 · see citing works

Harnessing the Power of Probiotics: Boosting Immunity and Safeguarding against Various Diseases and Infections

Singh, A., Mazumder, A., Das, S., Kanda, A., Tyagi, P. K., & Chaitanya, M. (2024) · Recent Advances in Anti-Infective Drug Discovery · doi:10.2174/0127724344308638240530065552 · Cited by 8 · see citing works

Effect of early life antibiotic use on serologic responses to oral rotavirus vaccine in the MAL-ED birth cohort study

Jean, D. T. S., McQuade, E. T. R., Edwards, J. K., Thompson, P., Thomas, J. C., & Becker‐Dreps, S. (2022) · Vaccine · doi:10.1016/j.vaccine.2022.03.023 · Cited by 6 · see citing works

Impact of maternal and pre-existing antibodies on immunogenicity of inactivated rotavirus vaccines

Zhou, Y., Hu, X., Chen, R., Wu, J., Lin, X., Lu, C., Yin, N., Tang, Y., Shi, P., Song, Z., et al. (2022) · Vaccine · doi:10.1016/j.vaccine.2022.05.036 · Cited by 5 · see citing works

Metabolomic Signatures Differentiate Immune Responses in Avian Influenza Vaccine Recipients

Howard, L. M., Jensen, T. L., Goll, J. B., Gelber, C. E., Bradley, M. D., Sherrod, S. D., Hoek, K. L., Yoder, S. M., Jimenez‐Truque, N., Edwards, K. M., et al. (2024) · The Journal of Infectious Diseases · doi:10.1093/infdis/jiad611 · Cited by 4 · see citing works

Fecal and vaginal microbiota of vaccinated and non-vaccinated pregnant elk challenged with Brucella abortus

Tibbs‐Cortes, B. W., Rahic-Seggerman, F. M., Schmitz‐Esser, S., Boggiatto, P. M., Olsen, S. C., & Putz, E. J. (2024) · Frontiers in Veterinary Science · doi:10.3389/fvets.2024.1334858 · Cited by 3 · see citing works

Using a Harm Reduction Model to Reduce Barriers to Vaccine Administration

Tharpe, N., & McDaniel, L. R. (2021) · Journal of Midwifery & Women s Health · doi:10.1111/jmwh.13259 · Cited by 3 · see citing works

The physiology of poverty: gut microbiome and pathways to child stunting

Hlongwa, N., Rich, K., Kelly, P. M., Ngobeni, R., Stone, W., von Fintel, M., Schenck, R., Swart, R., Makhalanyane, T. P., & Burger, R. (2026) · Philosophical Transactions of the Royal Society B Biological Sciences · doi:10.1098/rstb.2025.0034 · Cited by 2 · see citing works

Probiotics in Action: Enhancing Immunity and Combatting Diseases for Optimal Health

Singh, A., Mazumder, A., Das, S., Tyagi, P. K., & Chaitanya, M. (2024) · Journal of Natural Remedies · doi:10.18311/jnr/2024/35894 · Cited by 2 · see citing works

Fueling the Optimal Microbiome: Interventions for Severe Acute Malnutrition

Neu, J. (2019) · Cell Host & Microbe · doi:10.1016/j.chom.2019.08.015 · Cited by 2 · see citing works

Impact of Diet and Lifestyle on Vaccine Efficacy in Adults Aged 55 and Older: A Review.

Hodges, R., & Lamotte, A. V. (2022) · PubMed Central · Cited by 2 · see citing works

Composition, stabilization and delivery of virus-based vaccines: considerations to break free of the cold chain

Epoh, A. J., Doyle, J. H., Bajrovic, I., & Croyle, M. A. (2025) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2025.115715 · Cited by 1 · see citing works

Study of Cellular Immune Response and Some of the Blood Variables in Children with Celiac Disease

Ibrahim, R. K., Abdullah, Q. K., muhaidi, M., Khammas, R. K., & Hussein, N. M. (2021) · Journal of Physics Conference Series · doi:10.1088/1742-6596/1818/1/012011 · Cited by 1 · see citing works

Modern Germ-Free Study Designs and Emerging Static Housing Technology in a Growing “Human Microbiome” Research Market

Rodriguez‐Palacios, A. (2021) · Physiology in health and disease · doi:10.1007/978-3-030-67951-4_14 · Cited by 1 · see citing works

Reducing Broad-Spectrum Antibiotic Treatment of Simple Group A Streptococcal Infections to Reduce Harm to the Microbiome

Sumibcay, T. J., Lee-Jayaram, J. J., & Yamamoto, L. G. (2021) · Cureus · doi:10.7759/cureus.15629

El complejo histona acetiltransferasa B de la levadura Saccharomyces cerevisiae.

Gabaldón, P., & María, A. (2005) · TDX (Tesis Doctorals en Xarxa)

Role of immunobiotic lactic acid bacteria as vaccine adjuvants

Dadar, M., Shahali, Y., & Mojgani, N. (2021) · Elsevier eBooks · doi:10.1016/b978-0-12-823733-5.00012-x

Interactions between human microbiota and vaccines; Current perspectives

Keikha, M., Zandhaghighi, M., & Zahedani, S. S. (2023) · Vacunas · doi:10.1016/j.vacun.2022.12.006

Interactions between human microbiota and vaccines; Current perspectives

Keikha, M., Zandhaghighi, M., & Zahedani, S. S. (2023) · Vacunas (English Edition) · doi:10.1016/j.vacune.2023.07.007

Trends in Diarrhea Hospitalization among Children <5 Years Old Before and During the Covid-19 Season in Fako Division, Cameroon: A Situation Clouded by Sociopolitical Conflict

Loh, B. A. T., Ndze, V. N., Tangoh, D. A., Vuchuh, N. R., & Wepnje, G. B. (2023) · Texila international journal of public health · doi:10.21522/tijph.2013.11.04.art008

A Passion for Small Things and Staying Primed: My Career in Virology and Immunology

Saif, L. J. (2024) · Annual Review of Animal Biosciences · doi:10.1146/annurev-animal-111523-101937

Impact of Schistosoma mansoni Infection on the Gut Microbiome and Hepatitis B Vaccine Immune Response in Fishing Communities of Lake Victoria, Uganda

Wang, Y., Waters, A. K., Basalirwa, G., Ssetaala, A., Mpendo, J., Namuniina, A., Keneema, E., Kiiza, D., Kyosiimire–Lugemwa, J., Mayanja, Y., et al. (2025) · Vaccines · doi:10.3390/vaccines13040375

Exploring the Gut Microbiome and Its Role in Covid-19 Severity: A Focus on Sex Differences

Loukili, A., Jbara, S., Sehli, S., Ouafi, Z. E., Saber, S. O., Rfaki, A., Rhalem, W., Idrissi, N. A., Tissir, R., Allali, I., et al. (2025) · Lecture notes in networks and systems · doi:10.1007/978-3-031-91337-2_20

Diagnosis and treatment of fatigue in long COVID

Rudroff, T. (2025) · Elsevier eBooks · doi:10.1016/b978-0-443-24080-5.00036-9

Exploring the mechanism of Tongmai Yangxin pill in treating coronary heart disease by regulating gut microflora based on network pharmacology and molecular docking technology

Chai, Y., Li, N., Zhai, D., Chen, S., Li, Y., Tan, Y., Tang, X., Yang, Y., Pu, X., & Li, L. (2025) · Medicine · doi:10.1097/md.0000000000042780

Lactiplantibacillus plantarum CRL1506 ameliorates poly(I:C)-induced acute liver injury through cell wall-dependent modulation of inflammatory and antiviral immune responses

Pisarello, M. J. L., Baillo, A. A., Elean, M., Albarracín, L., Arellano-Arriagada, L., Suda, Y., Kitazawa, H., & Villena, J. (2026) · Food & Function · doi:10.1039/d6fo01160h

Disrupting the vicious cycle of malnutrition and enteropathy: advancing strategies to improve child physical and neurocognitive outcomes

Ijaz, M. K., Nims, R. W., Rubino, J. R., Hasan, B. S. F., Ijaz, M. K., Xu, F. Y., & Gerba, C. P. (2026) · Frontiers in Public Health · doi:10.3389/fpubh.2026.1792466

Modulation of immune responses to vaccination by the microbiota: implications and potential mechanisms

Lynn, D. J., Benson, S. C., Lynn, M. A., & Pulendran, B. (2021) · Nature reviews. Immunology · doi:10.1038/s41577-021-00554-7 · Cited by 300 · see citing works

Impact of the Host Microbiome on Vaccine Responsiveness: Lessons Learned and Future Perspective

Stefanetti, G., & Kasper, D. L. (2022) · Biochemistry · doi:10.1021/acs.biochem.2c00309 · Cited by 13 · see citing works

Nourishing the Microbiota to Promote Mucosal Immunity

Shenoy, M. K., & Koch, M. A. (2020) · Cell Host & Microbe · doi:10.1016/j.chom.2020.05.016 · Cited by 1 · see citing works

The Mammalian Intestinal Microbiome: Composition, Interaction with the Immune System, Significance for Vaccine Efficacy, and Potential for Disease Therapy

Desselberger, U. (2018) · Pathogens · doi:10.3390/pathogens7030057 · Cited by 55 · see citing works

Impact of the Gut Microbiota on Vaccine Responses

Azari, S., Siadat, S. D., Rahimi, P., Badi, S. A., Aghasadeghi, M. R., & Bahramali, G. (2021) · DOAJ (DOAJ: Directory of Open Access Journals)