Intestinal IgA production and its role in host-microbe interaction

Host-Bacterial Mutualism in the Human Intestine

Bäckhed, F., Ley, R. E., Sonnenburg, J. L., Peterson, D. A., & Gordon, J. I. (2005) · Science · doi:10.1126/science.1104816 · Cited by 5,277 · see citing works

Class Switch Recombination and Hypermutation Require Activation-Induced Cytidine Deaminase (AID), a Potential RNA Editing Enzyme

Muramatsu, M., Kinoshita, K., Fagarasan, S., Yamada, S., Shinkai, Y., & Honjo, T. (2000) · Cell · doi:10.1016/s0092-8674(00)00078-7 · Cited by 3,475 · see citing works

Follicular Helper CD4 T Cells (T _FH )

Crotty, S. (2011) · Annual Review of Immunology · doi:10.1146/annurev-immunol-031210-101400 · Cited by 2,738 · see citing works

A functionally specialized population of mucosal CD103+ DCs induces Foxp3+ regulatory T cells via a TGF-β– and retinoic acid–dependent mechanism

Coombes, J. L., Siddiqui, K. R. R., Arancibia-Cárcamo, C. V., Hall, J. A., Sun, C., Belkaid, Y., & Powrie, F. M. (2007) · The Journal of Experimental Medicine · doi:10.1084/jem.20070590 · Cited by 2,708 · see citing works

Dendritic cells express tight junction proteins and penetrate gut epithelial monolayers to sample bacteria

Rescigno, M., Urbano, M., Valzasina, B., Francolini, M., Rotta, G., Bonasio, R., Granucci, F., Kraehenbuhl, J.-P., & Ricciardi‐Castagnoli, P. (2001) · Nature Immunology · doi:10.1038/86373 · Cited by 2,554 · see citing works

Innate lymphoid cells — a proposal for uniform nomenclature

Spits, H., Artis, D., Colonna, M., Diefenbach, A., Disanto, J. D., Eberl, G., Koyasu, S., Locksley, R., McKenzie, A., Mebius, R., et al. (2013) · Nature reviews. Immunology · doi:10.1038/nri3365 · Cited by 2,380 · see citing works

The dendritic cell lineage: ontogeny and function of dendritic cells and their subsets in the steady state and the inflamed setting

Merad, M., Sathe, P., Helft, J., Miller, J., & Mortha, A. (2013) · Annual Review of Immunology · doi:10.1146/annurev-immunol-020711-074950 · Cited by 2,309 · see citing works

Role of the gut microbiota in immunity and inflammatory disease

Kamada, N., Seo, S.-U., Chen, G. Y., & Núñez, G. (2013) · Nature reviews. Immunology · doi:10.1038/nri3430 · Cited by 2,256 · see citing works

The Long-Term Stability of the Human Gut Microbiota

Faith, J. J., Guruge, J. L., Charbonneau, M., Subramanian, S., Seedorf, H., Goodman, A. L., Clemente, J. C., Knight, R., Heath, A. C., Leibel, R. L., et al. (2013) · Science · doi:10.1126/science.1237439 · Cited by 2,058 · see citing works

Small intestine lamina propria dendritic cells promote de novo generation of Foxp3 T reg cells via retinoic acid

Sun, C., Hall, J. A., Blank, R. B., Bouladoux, N. J., Oukka, M., Mora, J. R., & Belkaid, Y. (2007) · The Journal of Experimental Medicine · doi:10.1084/jem.20070602 · Cited by 1,880 · see citing works

Germinal Centers

Victora, G. D., & Nussenzweig, M. C. (2012) · Annual Review of Immunology · doi:10.1146/annurev-immunol-020711-075032 · Cited by 1,878 · see citing works

CX 3 CR1-Mediated Dendritic Cell Access to the Intestinal Lumen and Bacterial Clearance

Niess, J. H., Brand, S., Gu, X., Landsman, L., Jung, S., McCormick, B. A., Vyas, J. M., Boes, M. L., Ploegh, H. L., Fox, J. G., et al. (2005) · Science · doi:10.1126/science.1102901 · Cited by 1,609 · see citing works

The two mucus layers of colon are organized by the MUC2 mucin, whereas the outer layer is a legislator of host–microbial interactions

Johansson, M., Larsson, J. M. H., & Hansson, G. C. (2010) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1006451107 · Cited by 1,459 · see citing works

Immune adaptations that maintain homeostasis with the intestinal microbiota

Hooper, L. V., & Macpherson, A. J. (2010) · Nature reviews. Immunology · doi:10.1038/nri2710 · Cited by 1,455 · see citing works

The gastrointestinal mucus system in health and disease

Johansson, M. E. V., Sjövall, H., & Hansson, G. C. (2013) · Nature Reviews Gastroenterology & Hepatology · doi:10.1038/nrgastro.2013.35 · Cited by 1,438 · see citing works

Foxp3+ follicular regulatory T cells control the germinal center response

Linterman, M. A., Pierson, W., Lee, S. K., Kallies, A., Kawamoto, S., Rayner, T. F., Srivastava, M., Divekar, D. P., Beaton, L., Hogan, J. J., et al. (2011) · Nature Medicine · doi:10.1038/nm.2425 · Cited by 1,292 · see citing works

Mucosal vaccines: the promise and the challenge

Neutra, M. R., & Kozlowski, P. A. (2006) · Nature reviews. Immunology · doi:10.1038/nri1777 · Cited by 1,232 · see citing works

Follicular regulatory T cells expressing Foxp3 and Bcl-6 suppress germinal center reactions

Chung, Y., Tanaka, S., Chu, F., Nurieva, R. I., Martinez, G. J., Rawal, S., Wang, Y.-H., Lim, H., Reynolds, J. M., Zhou, X.-H., et al. (2011) · Nature Medicine · doi:10.1038/nm.2426 · Cited by 1,120 · see citing works

A Primitive T Cell-Independent Mechanism of Intestinal Mucosal IgA Responses to Commensal Bacteria

Macpherson, A. J., Gatto, D., Sainsbury, E., Harriman, G. R., Hengartner, H., & Zinkernagel, R. M. (2000) · Science · doi:10.1126/science.288.5474.2222 · Cited by 1,113 · see citing works

The immune geography of IgA induction and function

Macpherson, A. J., McCoy, K. D., Johansen, F.-E., & Brandtzaeg, P. (2007) · Mucosal Immunology · doi:10.1038/mi.2007.6 · Cited by 1,047 · see citing works

Generation of Gut-Homing IgA-Secreting B Cells by Intestinal Dendritic Cells

Mora, J. R., Iwata, M., Eksteen, B., Song, S., Junt, T., Senman, B. C., Otipoby, K. L., Yokota, A., Takeuchi, H., Ricciardi‐Castagnoli, P., et al. (2006) · Science · doi:10.1126/science.1132742 · Cited by 1,014 · see citing works

An essential function for the nuclear receptor RORγt in the generation of fetal lymphoid tissue inducer cells

Eberl, G., Marmon, S., Sunshine, M. J., Rennert, P. D., Choi, Y., & Littman, D. R. (2003) · Nature Immunology · doi:10.1038/ni1022 · Cited by 986 · see citing works

Goblet cells deliver luminal antigen to CD103+ dendritic cells in the small intestine

Mcdole, J. R., Wheeler, L. W., McDonald, K. G., Wang, B., Konjufca, V. H., Knoop, K. A., Newberry, R. D., & Miller, M. J. (2012) · Nature · doi:10.1038/nature10863 · Cited by 976 · see citing works

Immunoglobulin A (IgA): Molecular and Cellular Interactions Involved in IgA Biosynthesis and Immune Response

Mestecky, J. F., & McGhee, J. R. (1987) · Advances in immunology · doi:10.1016/s0065-2776(08)60240-0 · Cited by 947 · see citing works

Reversible Microbial Colonization of Germ-Free Mice Reveals the Dynamics of IgA Immune Responses

Hapfelmeier, S., Lawson, M. A. E., Slack, E., Kirundi, J. K., Stoel, M., Heikenwalder, M., Cahenzli, J., Velykoredko, Y., Balmer, M. L., Endt, K., et al. (2010) · Science · doi:10.1126/science.1188454 · Cited by 835 · see citing works

IgA Response to Symbiotic Bacteria as a Mediator of Gut Homeostasis

Peterson, D. A., McNulty, N. P., Guruge, J. L., & Gordon, J. I. (2007) · Cell Host & Microbe · doi:10.1016/j.chom.2007.09.013 · Cited by 828 · see citing works

Intestinal immune homeostasis is regulated by the crosstalk between epithelial cells and dendritic cells

Rimoldi, M., Chieppa, M., Salucci, V., Avogadri, F., Sonzogni, A., Sampietro, G. M., Nespoli, A., Viale, G., Allavena, P., & Rescigno, M. (2005) · Nature Immunology · doi:10.1038/ni1192 · Cited by 815 · see citing works

Dendritic cells in intestinal immune regulation

Coombes, J. L., & Powrie, F. M. (2008) · Nature reviews. Immunology · doi:10.1038/nri2335 · Cited by 792 · see citing works

The who, how and where of antigen presentation to B cells

Batista, F. D., & Harwood, N. E. (2008) · Nature reviews. Immunology · doi:10.1038/nri2454 · Cited by 775 · see citing works

The regulation of IgA class switching

Cerutti, A. (2008) · Nature reviews. Immunology · doi:10.1038/nri2322 · Cited by 756 · see citing works

Intestinal Bacteria Trigger T Cell-Independent Immunoglobulin A2 Class Switching by Inducing Epithelial-Cell Secretion of the Cytokine APRIL

He, B., Xu, W., Santini, P. A., Polydorides, A. D., Chiu, A., Estrella, J. S., Shan, M., Chadburn, A., Villanacci, V., Plebani, A., et al. (2007) · Immunity · doi:10.1016/j.immuni.2007.04.014 · Cited by 748 · see citing works

Regulation of humoral and cellular gut immunity by lamina propria dendritic cells expressing Toll-like receptor 5

Uematsu, S., Fujimoto, K., Jang, M. H., Yang, B., Jung, Y.-J., Nishiyama, M., Sato, S., Tsujimura, T., Yamamoto, M., Yokota, Y., et al. (2008) · Nature Immunology · doi:10.1038/ni.1622 · Cited by 746 · see citing works

Dynamic imaging of dendritic cell extension into the small bowel lumen in response to epithelial cell TLR engagement

Chieppa, M., Rescigno, M., Huang, A. Y.-C., & Germain, R. N. (2006) · The Journal of Experimental Medicine · doi:10.1084/jem.20061884 · Cited by 711 · see citing works

Multi-Faceted Functions of Secretory IgA at Mucosal Surfaces

Corthésy, B. (2013) · Frontiers in Immunology · doi:10.3389/fimmu.2013.00185 · Cited by 678 · see citing works

New concepts in the generation and functions of IgA

Pabst, O. (2012) · Nature reviews. Immunology · doi:10.1038/nri3322 · Cited by 656 · see citing works

Mucus Enhances Gut Homeostasis and Oral Tolerance by Delivering Immunoregulatory Signals

Shan, M., Gentile, M., Yeiser, J. R., Walland, A. C., Bornstein, V. U., Chen, K., He, B., Cassis, L., Bigas, A., Cols, M., et al. (2013) · Science · doi:10.1126/science.1237910 · Cited by 642 · see citing works

Uptake through glycoprotein 2 of FimH+ bacteria by M cells initiates mucosal immune response

Hase, K., Kawano, K., Nochi, T., Pontes, G., Fukuda, S., Ebisawa, M., Kadokura, K., Tobe, T., Fujimura, Y., Kawano, S., et al. (2009) · Nature · doi:10.1038/nature08529 · Cited by 625 · see citing works

Class-switch recombination: interplay of transcription, DNA deamination and DNA repair

Chaudhuri, J., & Alt, F. W. (2004) · Nature reviews. Immunology · doi:10.1038/nri1395 · Cited by 623 · see citing works

New insights into the development of lymphoid tissues

van de Pavert, S. A., & Mebius, R. E. (2010) · Nature reviews. Immunology · doi:10.1038/nri2832 · Cited by 597 · see citing works

Preferential Generation of Follicular B Helper T Cells from Foxp3 + T Cells in Gut Peyer's Patches

Tsuji, M., Komatsu, N., Kawamoto, S., Suzuki, K., Kanagawa, O., Honjo, T., Hori, S., & Fagarasan, S. (2009) · Science · doi:10.1126/science.1169152 · Cited by 592 · see citing works

Collaboration of epithelial cells with organized mucosal lymphoid tissues

Neutra, M. R., Mantis, N. J., & Kraehenbühl, J.-P. (2001) · Nature Immunology · doi:10.1038/ni1101-1004 · Cited by 580 · see citing works

TACI and BAFF-R mediate isotype switching in B cells

Castigli, E., Wilson, S. A., Scott, S., Dedeoğlu, F., Xu, S., Lam, K., Bram, R. J., Jabara, H. H., & Geha, R. S. (2005) · The Journal of Experimental Medicine · doi:10.1084/jem.20032000 · Cited by 544 · see citing works

Mucosal Dendritic Cells

Iwasaki, A. (2007) · Annual Review of Immunology · doi:10.1146/annurev.immunol.25.022106.141634 · Cited by 533 · see citing works

Plasticity of TH17 cells in Peyer's patches is responsible for the induction of T cell–dependent IgA responses

Hirota, K., Turner, J.-E., Villa, M., Duarte, J. H., Demengeot, J., Steinmetz, O. M., & Stockinger, B. (2013) · Nature Immunology · doi:10.1038/ni.2552 · Cited by 509 · see citing works

Activation of β-Catenin in Dendritic Cells Regulates Immunity Versus Tolerance in the Intestine

Manicassamy, S., Reizis, B., Ravindran, R., Nakaya, H. I., Gonzalez, R. M. S., Wang, Y., & Pulendran, B. (2010) · Science · doi:10.1126/science.1188510 · Cited by 500 · see citing works

Adaptive Immune Regulation in the Gut: T Cell–Dependent and T Cell–Independent IgA Synthesis

Fagarasan, S., Kawamoto, S., Kanagawa, O., & Suzuki, K. (2010) · Annual Review of Immunology · doi:10.1146/annurev-immunol-030409-101314 · Cited by 500 · see citing works

Oral Tolerance Can Be Established via Gap Junction Transfer of Fed Antigens from CX3CR1+ Macrophages to CD103+ Dendritic Cells

Mazzini, E., Massimiliano, L., Penna, G., & Rescigno, M. (2014) · Immunity · doi:10.1016/j.immuni.2013.12.012 · Cited by 474 · see citing works

Microbiota restricts trafficking of bacteria to mesenteric lymph nodes by CX3CR1hi cells

Diehl, G. E., Longman, R., Zhang, J.-X., Bréart, B., Galan, C., Cuesta, A., Schwab, S. R., & Littman, D. R. (2013) · Nature · doi:10.1038/nature11809 · Cited by 472 · see citing works

Dysregulation of germinal centres in autoimmune disease

Vinuesa, C. G., Sanz, I., & Cook, M. (2009) · Nature reviews. Immunology · doi:10.1038/nri2637 · Cited by 465 · see citing works

Luminal Bacteria Recruit CD103+ Dendritic Cells into the Intestinal Epithelium to Sample Bacterial Antigens for Presentation

Farache, J., Koren, I., Milo, I., Gurevich, I., Kim, K.-W., Zigmond, E., Furtado, G. C., Lira, S. A., & Shakhar, G. (2013) · Immunity · doi:10.1016/j.immuni.2013.01.009 · Cited by 456 · see citing works

The Inhibitory Receptor PD-1 Regulates IgA Selection and Bacterial Composition in the Gut

Kawamoto, S., Tran, T. H., Maruya, M., Suzuki, K., Doi, Y., Tsutsui, Y., Kato, L. M., & Fagarasan, S. (2012) · Science · doi:10.1126/science.1217718 · Cited by 451 · see citing works

Requirement for Lymphoid Tissue-Inducer Cells in Isolated Follicle Formation and T Cell-Independent Immunoglobulin A Generation in the Gut

Tsuji, M., Suzuki, K., Kitamura, H., Maruya, M., Kinoshita, K., Ivanov, I. I., Itoh, K., Littman, D. R., & Fagarasan, S. (2008) · Immunity · doi:10.1016/j.immuni.2008.05.014 · Cited by 441 · see citing works

A dominant, coordinated T regulatory cell-IgA response to the intestinal microbiota

Cong, Y., Feng, T., Fujihashi, K., Schoeb, T. R., & Elson, C. O. (2009) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0812681106 · Cited by 430 · see citing works

Secretory Component

Phalipon, A., Cardona, A., Kraehenbuhl, J.-P., Edelman, L., Sansonetti, P. J., & Corthésy, B. (2002) · Immunity · doi:10.1016/s1074-7613(02)00341-2 · Cited by 426 · see citing works

Absence of Epithelial Immunoglobulin a Transport, with Increased Mucosal Leakiness, in Polymeric Immunoglobulin Receptor/Secretory Component–Deficient Mice

Johansen, F., Pekna, M., Norderhaug, I. N., Haneberg, B., Hietala, M. A., Krajči, P., Betsholtz, C., & Brandtzæg, P. (1999) · The Journal of Experimental Medicine · doi:10.1084/jem.190.7.915 · Cited by 417 · see citing works

Direct evidence for an integrated function of J chain and secretory component in epithelial transport of immunoglobulins

Brandtzaeg, P., & Prydz, H. (1984) · Nature · doi:10.1038/311071a0 · Cited by 415 · see citing works

Regulation of IgA production by naturally occurring TNF/iNOS-producing dendritic cells

Tezuka, H., Abe, Y., Iwata, M., Takeuchi, H., Ishikawa, H., Matsushita, M., Shiohara, T., Akira, S., & Ohteki, T. (2007) · Nature · doi:10.1038/nature06033 · Cited by 413 · see citing works

Immunoglobulin Responses at the Mucosal Interface

Cerutti, A., Chen, K., & Chorny, A. (2011) · Annual Review of Immunology · doi:10.1146/annurev-immunol-031210-101317 · Cited by 391 · see citing works

Human intestinal epithelial cells promote the differentiation of tolerogenic dendritic cells

Iliev, I. D., Spadoni, I., Mileti, E., Matteoli, G., Sonzogni, A., Sampietro, G. M., Foschi, D., Caprioli, F., Viale, G., & Rescigno, M. (2009) · Gut · doi:10.1136/gut.2008.175166 · Cited by 389 · see citing works

Targeting of somatic hypermutation

Odegard, V. H., & Schatz, D. G. (2006) · Nature reviews. Immunology · doi:10.1038/nri1896 · Cited by 380 · see citing works

Intestinal epithelial cells promote colitis-protective regulatory T-cell differentiation through dendritic cell conditioning

Iliev, I. D., Mileti, E., Matteoli, G., Chieppa, M., & Rescigno, M. (2009) · Mucosal Immunology · doi:10.1038/mi.2009.13 · Cited by 354 · see citing works

The transmembrane activator TACI triggers immunoglobulin class switching by activating B cells through the adaptor MyD88

He, B., Santamaría, R., Xu, W., Cols, M., Chen, K., Puga, I., Shan, M., Xiong, H., Bussel, J. B., Chiu, A., et al. (2010) · Nature Immunology · doi:10.1038/ni.1914 · Cited by 349 · see citing works

Gastrointestinal Pathology in Patients with Common Variable Immunodeficiency and X-Linked Agammaglobulinemia

Washington, K. M., Stenzel, T. T., Buckley, R. H., & Gottfried, M. R. (1996) · The American Journal of Surgical Pathology · doi:10.1097/00000478-199610000-00010 · Cited by 333 · see citing works

Intestinal CD103+ dendritic cells: master regulators of tolerance?

Scott, C. L., Aumeunier, A., & Mowat, A. M. (2011) · Trends in Immunology · doi:10.1016/j.it.2011.06.003 · Cited by 322 · see citing works

Regulation of IgA production by naturally occurring TNF/iNOS-producing dendritic cells

手塚, 裕., 安部, 由., & 樗木, 俊. (2008) · 生体の科学 · Cited by 322 · see citing works

The role of secretory antibodies in infection immunity

Strugnell, R. A., & Wijburg, O. L. C. (2010) · Nature Reviews Microbiology · doi:10.1038/nrmicro2384 · Cited by 320 · see citing works

Polymeric immunoglobulin receptor expressed in MDCK cells transcytoses IgA

Mostov, K. E., & Deitcher, D. L. (1986) · Cell · doi:10.1016/0092-8674(86)90887-1 · Cited by 319 · see citing works

HIV-1 evades virus-specific IgG2 and IgA responses by targeting systemic and intestinal B cells via long-range intercellular conduits

Xu, W., Santini, P. A., Sullivan, J. S., He, B., Shan, M., Ball, S. C., Dyer, W. B., Ketas, T. J., Chadburn, A., Cohen-Gould, L., et al. (2009) · Nature Immunology · doi:10.1038/ni.1753 · Cited by 302 · see citing works

Immunity and correlates of protection for rotavirus vaccines

Franco, M. A., Angel, J., & Greenberg, H. B. (2006) · Vaccine · doi:10.1016/j.vaccine.2005.12.048 · Cited by 268 · see citing works

Peyer's Patch Dendritic Cells Sample Antigens by Extending Dendrites Through M Cell-Specific Transcellular Pores

Lelouard, H., Fallet, M., de Bovis, B., Méresse, S., & Gorvel, J. (2011) · Gastroenterology · doi:10.1053/j.gastro.2011.11.039 · Cited by 263 · see citing works

Nonredundant Function of Soluble LTα 3 Produced by Innate Lymphoid Cells in Intestinal Homeostasis

Kruglov, A., Grivennikov, S. I., Kuprash, D. V., Winsauer, C., Prepens, S., Seleznik, G. M., Eberl, G., Littman, D. R., Heikenwälder, M. F., Tumanov, A. V., et al. (2013) · Science · doi:10.1126/science.1243364 · Cited by 262 · see citing works

Regulation of AID expression in the immune response

Crouch, E. E., Li, Z., Takizawa, M., Fichtner‐Feigl, S., Gourzi, P., Montaño, C., Feigenbaum, L., Wilson, P. C., Janz, S., Papavasiliou, F. N., et al. (2007) · The Journal of Experimental Medicine · doi:10.1084/jem.20061952 · Cited by 258 · see citing works

The majority of intestinal IgA+ and IgG+ plasmablasts in the human gut are antigen-specific

Benckert, J., Schmolka, N., Kreschel, C., Zöller, M., Sturm, A., Wiedenmann, B. J., & Wardemann, H. (2011) · Journal of Clinical Investigation · doi:10.1172/jci44447 · Cited by 256 · see citing works

The Sensing of Environmental Stimuli by Follicular Dendritic Cells Promotes Immunoglobulin A Generation in the Gut

Suzuki, K., Maruya, M., Kawamoto, S., Sitnik, K., Kitamura, H., Agace, W. W., & Fagarasan, S. (2010) · Immunity · doi:10.1016/j.immuni.2010.07.003 · Cited by 250 · see citing works

Age, microbiota, and T cells shape diverse individual IgA repertoires in the intestine

Lindner, C., Wahl, B., Föhse, L., Suerbaum, S., Macpherson, A. J., Prinz, I., & Pabst, O. (2012) · The Journal of Experimental Medicine · doi:10.1084/jem.20111980 · Cited by 234 · see citing works

Selective Adherence of IgA to Murine Peyer’s Patch M Cells: Evidence for a Novel IgA Receptor

Mantis, N. J., Cheung, M. C., Chintalacharuvu, K. R., Rey, J., Corthésy, B., & Neutra, M. R. (2002) · The Journal of Immunology · doi:10.4049/jimmunol.169.4.1844 · Cited by 228 · see citing works

IgA production without μ or δ chain expression in developing B cells

Macpherson, A. J. S., Lamarre, A., McCoy, K., Harriman, G. R., Odermatt, B., Dougan, G., Hengartner, H., & Zinkernagel, R. M. (2001) · Nature Immunology · doi:10.1038/89775 · Cited by 223 · see citing works

Prominent Role for Plasmacytoid Dendritic Cells in Mucosal T Cell-Independent IgA Induction

Tezuka, H., Abe, Y., Asano, J., Sato, T., Liu, J., Iwata, M., & Ohteki, T. (2011) · Immunity · doi:10.1016/j.immuni.2011.02.002 · Cited by 222 · see citing works

How T Cells Earn the Follicular Rite of Passage

Vinuesa, C. G., & Cyster, J. G. (2011) · Immunity · doi:10.1016/j.immuni.2011.11.001 · Cited by 211 · see citing works

To be or not to be a pathogen: that is the mucosally relevant question

Sansonetti, P. J. (2010) · Mucosal Immunology · doi:10.1038/mi.2010.77 · Cited by 198 · see citing works

Dectin-1 Is Essential for Reverse Transcytosis of Glycosylated SIgA-Antigen Complexes by Intestinal M Cells

Rochereau, N., Drocourt, D., Pérouzel, É., Pavot, V., Redelinghuys, P., Brown, G. D., Tiraby, G., Roblin, X., Verrier, B., Genin, C., et al. (2013) · PLoS Biology · doi:10.1371/journal.pbio.1001658 · Cited by 193 · see citing works

Role of secretory IgA in infection and maintenance of homeostasis

Corthésy, B. (2012) · Autoimmunity Reviews · doi:10.1016/j.autrev.2012.10.012 · Cited by 190 · see citing works

Presence of J chain in human immunocytes containing various immunoglobulin classes

Brandtzæg, P. (1974) · Nature · doi:10.1038/252418a0 · Cited by 188 · see citing works

IgA Class Switch Occurs in the Organized Nasopharynx- and Gut-Associated Lymphoid Tissue, but Not in the Diffuse Lamina Propria of Airways and Gut

Shikina, T., Hiroi, T., Iwatani, K., Jang, M. H., Fukuyama, S., Tamura, M., Kubo, T., Ishikawa, H., & Kiyono, H. (2004) · The Journal of Immunology · doi:10.4049/jimmunol.172.10.6259 · Cited by 177 · see citing works

Antigen sampling in the small intestine

Schulz, O., & Pabst, O. (2012) · Trends in Immunology · doi:10.1016/j.it.2012.09.006 · Cited by 174 · see citing works

Role of retinoic acid in the imprinting of gut-homing IgA-secreting cells

Mora, J. R., & von Andrian, U. H. (2008) · Seminars in Immunology · doi:10.1016/j.smim.2008.08.002 · Cited by 174 · see citing works

Secretory IgA Mediates Bacterial Translocation to Dendritic Cells in Mouse Peyer’s Patches with Restriction to Mucosal Compartment

Kadaoui, K. A., & Corthésy, B. (2007) · The Journal of Immunology · doi:10.4049/jimmunol.179.11.7751 · Cited by 172 · see citing works

Gut IgA Class Switch Recombination in the Absence of CD40 Does Not Occur in the Lamina Propria and Is Independent of Germinal Centers

Bergqvist, P. J., Gärdby, E., Stensson, A., Bemark, M., & Lycke, N. Y. (2006) · The Journal of Immunology · doi:10.4049/jimmunol.177.11.7772 · Cited by 165 · see citing works

Secretory Component Delays the Conversion of Secretory IgA into Antigen-Binding Competent F(ab′)2: A Possible Implication for Mucosal Defense

Crottet, P., & Corthésy, B. (1998) · The Journal of Immunology · doi:10.4049/jimmunol.161.10.5445 · Cited by 162 · see citing works

A T Cell-Dependent Mechanism for the Induction of Human Mucosal Homing Immunoglobulin A-Secreting Plasmablasts

Dullaers, M., Li, D., Xue, Y., Ni, L., Gayet, I., Morita, R., Ueno, H., Palucka, K. A., Banchereau, J., & Oh, S. (2009) · Immunity · doi:10.1016/j.immuni.2008.11.008 · Cited by 137 · see citing works

T Cell-Independent IgA Class Switch Recombination Is Restricted to the GALT and Occurs Prior to Manifest Germinal Center Formation

Bergqvist, P. J., Stensson, A., Lycke, N. Y., & Bemark, M. (2010) · The Journal of Immunology · doi:10.4049/jimmunol.0901895 · Cited by 131 · see citing works

Viral Double-Stranded RNA Triggers Ig Class Switching by Activating Upper Respiratory Mucosa B Cells through an Innate TLR3 Pathway Involving BAFF

Xu, W., Santini, P. A., Matthews, A. J., Chiu, A., Plebani, A., He, B., Chen, K., & Cerutti, A. (2008) · The Journal of Immunology · doi:10.4049/jimmunol.181.1.276 · Cited by 117 · see citing works

Re-utilization of germinal centers in multiple Peyer's patches results in highly synchronized, oligoclonal, and affinity-matured gut IgA responses

Bergqvist, P. J., Stensson, A., Hazanov, L., Holmberg, A. H., Mattsson, J., Mehr, R., Bemark, M., & Lycke, N. Y. (2012) · Mucosal Immunology · doi:10.1038/mi.2012.56 · Cited by 103 · see citing works

IgA subclass switch recombination in human mucosal and systemic immune compartments

Lin, M., Du, L., Brandtzaeg, P., & Pan‐Hammarström, Q. (2013) · Mucosal Immunology · doi:10.1038/mi.2013.68 · Cited by 94 · see citing works

Gut-associated lymphoid tissue contains the molecular machinery to support T-cell-dependent and T-cell-independent class switch recombination

Barone, F., Patel, P., Sanderson, J. D., & Spencer, J. (2009) · Mucosal Immunology · doi:10.1038/mi.2009.106 · Cited by 93 · see citing works

A role for gut-associated lymphoid tissue in shaping the human B cell repertoire

Vossenkämper, A., Blair, P. A., Safinia, N., Fraser, L. D., Das, L., Sanders, T. J., Stagg, A. J., Sanderson, J. D., Taylor, K. M., Chang, F., et al. (2013) · The Journal of Experimental Medicine · doi:10.1084/jem.20122465 · Cited by 92 · see citing works

Secretory IgA Induces Tolerogenic Dendritic Cells through SIGNR1 Dampening Autoimmunity in Mice

Diana, J., Moura, I. C., Vaugier, C., Gestin, A., Tissandié, E., Beaudoin, L., Corthésy, B., Hocini, H., Lehuen, A., & Monteiro, R. C. (2013) · The Journal of Immunology · doi:10.4049/jimmunol.1300864 · Cited by 83 · see citing works

Retinoic acid, acting as a highly specific IgA isotype switch factor, cooperates with TGF-β1 to enhance the overall IgA response

Seo, G., Jang, Y., Kim, H.-A., Lee, M.-R., Park, M., Park, S., Lee, J.-M., Choe, J., & Kim, P.-H. (2013) · Journal of Leukocyte Biology · doi:10.1189/jlb.0313128 · Cited by 78 · see citing works

Recognition of secretory IgA by DC-SIGN: Implications for immune surveillance in the intestine

Baumann, J., Park, C. G., & Mantis, N. J. (2010) · Immunology Letters · doi:10.1016/j.imlet.2010.03.005 · Cited by 76 · see citing works

The Regulatory Effects of All-trans-Retinoic Acid on Isotype Switching: Retinoic Acid Induces IgA Switch Rearrangement in Cooperation with IL-5 and Inhibits IgG1 Switching

Tokuyama, H., & Tokuyama, Y. (1999) · Cellular Immunology · doi:10.1006/cimm.1998.1438 · Cited by 59 · see citing works

Lymphotoxin Alpha-Deficient Mice Clear Persistent Rotavirus Infection after Local Generation of Mucosal IgA

Lopatin, U. A., Blutt, S. E., Conner, M. E., & Kelsall, B. L. (2012) · Journal of Virology · doi:10.1128/jvi.01801-12 · Cited by 27 · see citing works

Lineage-dependent gene expression programs influence the immune landscape of colorectal cancer

Lee, H., Hong, Y., Etlioglu, H. E., Cho, Y. B., Pomella, V., den Bosch, B. V., Vanhecke, J., Verbandt, S., Hong, H.-K., Min, J.-W., et al. (2020) · Nature Genetics · doi:10.1038/s41588-020-0636-z · Cited by 916 · see citing works

Gut Microbial Metabolites Fuel Host Antibody Responses

Kim, M., Qie, Y., Park, J., & Kim, C. H. (2016) · Cell Host & Microbe · doi:10.1016/j.chom.2016.07.001 · Cited by 893 · see citing works

Probiotics Mechanism of Action on Immune Cells and Beneficial Effects on Human Health

Mazziotta, C., Tognon, M., Martini, F., Torreggiani, E., & Rotondo, J. C. (2023) · Cells · doi:10.3390/cells12010184 · Cited by 889 · see citing works

Single-cell atlas of lineage states, tumor microenvironment, and subtype-specific expression programs in gastric cancer

Kumar, V., Ramnarayanan, K., Sundar, R., Padmanabhan, N., Srivastava, S., Koiwa, M., Yasuda, T., Koh, V., Huang, K. K., Tay, S. T., et al. (2022) · Cancer Discovery · doi:10.1158/2159-8290.cd-21-0683 · Cited by 573 · see citing works

Functions of Gut Microbiota Metabolites, Current Status and Future Perspectives

Liu, J., Tan, Y., Cheng, H., Zhang, D., Feng, W., & Peng, C. (2022) · Aging and disease · doi:10.14336/ad.2022.0104 · Cited by 529 · see citing works

Addressing global ruminant agricultural challenges through understanding the rumen microbiome: past, present, and future

Huws, S. A., Creevey, C. J., Oyama, L. B., Mizrahi, I., Denman, S. E., Popova, M., Muñoz-Tamayo, R., Forano, E., Waters, S. M., Hess, M., et al. (2018) · Frontiers in Microbiology · doi:10.3389/fmicb.2018.02161 · Cited by 487 · see citing works

The Intestinal Barrier and Current Techniques for the Assessment of Gut Permeability

Schoultz, I., & Keita, Å. V. (2020) · Cells · doi:10.3390/cells9081909 · Cited by 479 · see citing works

Precision Nutrition and the Microbiome, Part I: Current State of the Science

Mills, S., Stanton, C., Lane, J. A., Smith, G., & Ross, R. P. (2019) · Nutrients · doi:10.3390/nu11040923 · Cited by 406 · see citing works

Rethinking mucosal antibody responses: IgM, IgG and IgD join IgA

Chen, K., Magri, G., Grasset, E. K., & Cerutti, A. (2020) · Nature reviews. Immunology · doi:10.1038/s41577-019-0261-1 · Cited by 339 · see citing works

Peyer's patches: organizing B‐cell responses at the intestinal frontier

Reboldi, A., & Cyster, J. G. (2016) · Immunological Reviews · doi:10.1111/imr.12400 · Cited by 309 · see citing works

Potential intestinal infection and faecal–oral transmission of SARS-CoV-2

Guo, M., Tao, W., Flavell, R. A., & Zhu, S. (2021) · Nature Reviews Gastroenterology & Hepatology · doi:10.1038/s41575-021-00416-6 · Cited by 305 · see citing works

Gut Microbiome, Intestinal Permeability, and Tissue Bacteria in Metabolic Disease: Perpetrators or Bystanders?

Chakaroun, R., Massier, L., & Kovacs, P. L. (2020) · Nutrients · doi:10.3390/nu12041082 · Cited by 297 · see citing works

IgA Function in Relation to the Intestinal Microbiota

Macpherson, A. J., Yılmaz, B., Limenitakis, J. P., & Ganal-Vonarburg, S. C. (2018) · Annual Review of Immunology · doi:10.1146/annurev-immunol-042617-053238 · Cited by 291 · see citing works

Mucosal immunoglobulins at respiratory surfaces mark an ancient association that predates the emergence of tetrapods

Xu, Z., Takizawa, F., Parra, D., Gómez, D., Jørgensen, L. V. G., LaPatra, S. E., & Sunyer, J. O. (2016) · Nature Communications · doi:10.1038/ncomms10728 · Cited by 287 · see citing works

Secretory IgA in Intestinal Mucosal Secretions as an Adaptive Barrier against Microbial Cells

Pietrzak, B., Tomela, K., Olejnik‐Schmidt, A., Mackiewicz, A. A., & SCHMIDT, M. T. (2020) · International Journal of Molecular Sciences · doi:10.3390/ijms21239254 · Cited by 281 · see citing works

Antigen sampling by intestinal M cells is the principal pathway initiating mucosal IgA production to commensal enteric bacteria

Ríos, D., Wood, M. B., Li, J., Chassaing, B., Gewirtz, A. T., & Williams, I. R. (2015) · Mucosal Immunology · doi:10.1038/mi.2015.121 · Cited by 266 · see citing works

Childhood Development and the Microbiome—The Intestinal Microbiota in Maintenance of Health and Development of Disease During Childhood Development

Ronan, V., Yeasin, R., & Claud, E. C. (2020) · Gastroenterology · doi:10.1053/j.gastro.2020.08.065 · Cited by 268 · see citing works

Inducing Mucosal IgA: A Challenge for Vaccine Adjuvants and Delivery Systems

Boyaka, P. N. (2017) · The Journal of Immunology · doi:10.4049/jimmunol.1601775 · Cited by 258 · see citing works

Mechanisms of mucosal healing: treating inflammatory bowel disease without immunosuppression?

Villablanca, E. J., Selin, K., & Hedin, C. R. H. (2022) · Nature Reviews Gastroenterology & Hepatology · doi:10.1038/s41575-022-00604-y · Cited by 258 · see citing works

Nutrients Mediate Intestinal Bacteria–Mucosal Immune Crosstalk

Ma, N., Guo, P., Zhang, J., He, T., Kim, S. W., Zhang, G., & Ma, X. (2018) · Frontiers in Immunology · doi:10.3389/fimmu.2018.00005 · Cited by 249 · see citing works

Pas de Deux: Control of Anti-tumor Immunity by Cancer-Associated Inflammation

Shalapour, S., & Karin, M. (2019) · Immunity · doi:10.1016/j.immuni.2019.06.021 · Cited by 229 · see citing works

The Connection Between Physical Exercise and Gut Microbiota: Implications for Competitive Sports Athletes

Wegierska, A. E., Charitos, I. A., Topi, S., Potenza, M. A., Montagnani, M., & Santacroce, L. (2022) · Sports Medicine · doi:10.1007/s40279-022-01696-x · Cited by 239 · see citing works

Akkermansia muciniphila ameliorates the age-related decline in colonic mucus thickness and attenuates immune activation in accelerated aging Ercc1−/Δ7 mice

van der Lugt, B., van Beek, A. A., Aalvink, S., Meijer, B., Sovran, B., Vermeij, W. P., Brandt, R. M. C., de Vos, W. M., Savelkoul, H. F. J., Steegenga, W. T., et al. (2019) · Immunity & Ageing · doi:10.1186/s12979-019-0145-z · Cited by 217 · see citing works

Altered microbiota associated with abnormal humoral immune responses to commensal organisms in enthesitis-related arthritis

Stoll, M. L., Kumar, R., Morrow, C. D., Lefkowitz, E. J., Cui, X., Genin, A., Cron, R. Q., & Elson, C. O. (2014) · Arthritis Research & Therapy · doi:10.1186/s13075-014-0486-0 · Cited by 208 · see citing works

Gut-associated IgA+ immune cells regulate obesity-related insulin resistance

Luck, H., Khan, S. M., Kim, J. H., Copeland, J. K., Revelo, X. S., Tsai, S. J., Chakraborty, M., Cheng, K., Chan, Y. T., Nøhr, M. K., et al. (2019) · Nature Communications · doi:10.1038/s41467-019-11370-y · Cited by 204 · see citing works

Functions and regulation of T cell-derived interleukin-10

Neumann, C., Scheffold, A., & Rutz, S. (2019) · Seminars in Immunology · doi:10.1016/j.smim.2019.101344 · Cited by 198 · see citing works

Protective Microbiota: From Localized to Long-Reaching Co-Immunity

Chiu, L., Bazin, T., Truchetet, M., Schaeverbeke, T., Delhaès, L., & Pradeu, T. (2017) · Frontiers in Immunology · doi:10.3389/fimmu.2017.01678 · Cited by 192 · see citing works

Death in the intestinal epithelium—basic biology and implications for inflammatory bowel disease

Blander, J. M. (2016) · FEBS Journal · doi:10.1111/febs.13771 · Cited by 191 · see citing works

Aberrant IgA responses to the gut microbiota during infancy precede asthma and allergy development

Dzidic, M., Abrahamsson, T., Artacho, A., Björkstén, B., Collado, M. C., Mira, Á., & Jenmalm, M. C. (2016) · Journal of Allergy and Clinical Immunology · doi:10.1016/j.jaci.2016.06.047 · Cited by 173 · see citing works

Understanding the gut microbiome of dairy calves: Opportunities to improve early-life gut health

Malmuthuge, N., & Guan, L. L. (2017) · Journal of Dairy Science · doi:10.3168/jds.2016-12239 · Cited by 167 · see citing works

Natural acquisition and spontaneous elimination of Helicobacter pylori infection: clinical implications.

Xia, H. H. X., & Talley, N. J. (1997) · PubMed · Cited by 161 · see citing works

The enigmatic function of IgD: some answers at last

Gutzeit, C., Chen, K., & Cerutti, A. (2018) · European Journal of Immunology · doi:10.1002/eji.201646547 · Cited by 159 · see citing works

The mucosal immune system and IgA nephropathy

Gesualdo, L., Leo, V. D., & Coppo, R. (2021) · Seminars in Immunopathology · doi:10.1007/s00281-021-00871-y · Cited by 160 · see citing works

Analysis of the intestinal microbiota in COVID-19 patients and its correlation with the inflammatory factor IL-18

Tao, W., Zhang, G., Wang, X., Guo, M., Zeng, W., Xu, Z., Cao, D., Pan, A., Wang, Y., Zhang, K., et al. (2020) · Medicine in Microecology · doi:10.1016/j.medmic.2020.100023 · Cited by 154 · see citing works

Mammary microbiota of dairy ruminants: fact or fiction?

Rainard, P. (2017) · Veterinary Research · doi:10.1186/s13567-017-0429-2 · Cited by 137 · see citing works

Asymptomatic Intestinal Colonization with Protist Blastocystis Is Strongly Associated with Distinct Microbiome Ecological Patterns

Nieves, M., Partida‐Rodríguez, O., Laforest‐Lapointe, I., Reynolds, L. A., Brown, E., Valdez-Salazar, A., Morán-Silva, P., Rojas-Velázquez, L., Morien, E., Parfrey, L. W., et al. (2018) · mSystems · doi:10.1128/msystems.00007-18 · Cited by 136 · see citing works

Intestinal microbiota and its interaction to intestinal health in nursery pigs

Duarte, M. E., & Kim, S. W. (2021) · Animal nutrition · doi:10.1016/j.aninu.2021.05.001 · Cited by 134 · see citing works

Fostering of advanced mutualism with gut microbiota by Immunoglobulin A

Sutherland, D. B., Suzuki, K., & Fagarasan, S. (2016) · Immunological Reviews · doi:10.1111/imr.12384 · Cited by 115 · see citing works

Role of secretory IgA in the mucosal sensing of commensal bacteria

Mathias, A., Pais, B., Favre, L., Benyacoub, J., & Corthésy, B. (2014) · Gut Microbes · doi:10.4161/19490976.2014.983763 · Cited by 115 · see citing works

Postbiotic L. plantarum RG14 improves ruminal epithelium growth, immune status and upregulates the intestinal barrier function in post-weaning lambs

Izuddin, W. I., Loh, T. C., Foo, H. L., Samsudin, A. A., & Humam, A. M. (2019) · Scientific Reports · doi:10.1038/s41598-019-46076-0 · Cited by 110 · see citing works

Gut commensals and their metabolites in health and disease

Krishnamurthy, H. K., Pereira, M., Bosco, J., George, J., Jayaraman, V., Krishna, K., Wang, T., Bei, K., & Rajasekaran, J. J. (2023) · Frontiers in Microbiology · doi:10.3389/fmicb.2023.1244293 · Cited by 110 · see citing works

Postbiotics as Metabolites and Their Biotherapeutic Potential

Hijová, E. (2024) · International Journal of Molecular Sciences · doi:10.3390/ijms25105441 · Cited by 117 · see citing works

The Peyer’s Patch Mononuclear Phagocyte System at Steady State and during Infection

Silva, C. D., Wagner, C., Bonnardel, J., Gorvel, J., & Lelouard, H. (2017) · Frontiers in Immunology · doi:10.3389/fimmu.2017.01254 · Cited by 105 · see citing works

From the intestinal flora to the microbiome

Domingo, J. J. S., & Sánchez, C. S. (2017) · Revista Española de Enfermedades Digestivas · doi:10.17235/reed.2017.4947/2017 · Cited by 105 · see citing works

A Soluble Fiber Diet Increases Bacteroides fragilis Group Abundance and Immunoglobulin A Production in the Gut

Nakajima, A., Sasaki, T., Itoh, K., Kitahara, T., Takema, Y., Hiramatsu, K., Ishikawa, D., Shibuya, T., Kobayashi, O., Osada, T., et al. (2020) · Applied and Environmental Microbiology · doi:10.1128/aem.00405-20 · Cited by 104 · see citing works

The Many Functions of Foxp3+ Regulatory T Cells in the Intestine

Cosovanu, C., & Neumann, C. (2020) · Frontiers in Immunology · doi:10.3389/fimmu.2020.600973 · Cited by 104 · see citing works

Intestinal microbiota: a new force in cancer immunotherapy

Dai, Z., Zhang, J., Wu, Q., Fang, H., Shi, C., Li, Z., Lin, C., Tang, D., & Wang, D. (2020) · Cell Communication and Signaling · doi:10.1186/s12964-020-00599-6 · Cited by 98 · see citing works

Incidence, timing, and management of infections in patients receiving teclistamab for the treatment of relapsed/refractory multiple myeloma in the MajesTEC‐1 study

Nooka, A. K., Rodriguez, C., Mateos, M., Manier, S., Chastain, K. M., Banerjee, A., Kobos, R., Qi, K., Verona, R. I., Doyle, M., et al. (2023) · Cancer · doi:10.1002/cncr.35107 · Cited by 97 · see citing works

Bugging allergy; role of pre-, pro- and synbiotics in allergy prevention

West, C. E., Dzidic, M., Prescott, S. L., & Jenmalm, M. C. (2017) · Allergology International · doi:10.1016/j.alit.2017.08.001 · Cited by 95 · see citing works

Effect of synbiotic supplementation on immune parameters and gut microbiota in healthy adults: a double-blind randomized controlled trial

Li, X., Hu, S., Yin, J., Peng, X., King, L., Li, L., Xu, Z., Zhou, L., Peng, Z., Ze, X., et al. (2023) · Gut Microbes · doi:10.1080/19490976.2023.2247025 · Cited by 94 · see citing works

MZB1 promotes the secretion of J-chain–containing dimeric IgA and is critical for the suppression of gut inflammation

Xiong, E., Li, Y., Min, Q., Cui, C., Liu, J., Hong, R., Lai, N., Wang, Y., Sun, J., Matsumoto, R., et al. (2019) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1904204116 · Cited by 90 · see citing works

The effects of dietary fibers from rice bran and wheat bran on gut microbiota: An overview

Yao, W., Gong, Y., Li, C., Hu, X., & You, L. (2022) · Food Chemistry X · doi:10.1016/j.fochx.2022.100252 · Cited by 90 · see citing works

Specific microbiota enhances intestinal IgA levels by inducing TGF‐β in T follicular helper cells of Peyer's patches in mice

Beller, A. V., Kruglov, A., Durek, P., von Goetze, V., Werner, K., Heinz, G. A., Ninnemann, J., Lehmann, K., Maier, R., Hoffmann, U., et al. (2020) · European Journal of Immunology · doi:10.1002/eji.201948474 · Cited by 88 · see citing works

The Gut-Kidney Axis: Putative Interconnections Between Gastrointestinal and Renal Disorders

Lehto, M. J., & Groop, P. (2018) · Frontiers in Endocrinology · doi:10.3389/fendo.2018.00553 · Cited by 86 · see citing works

Is intestinal inflammation linking dysbiosis to gut barrier dysfunction during liver disease?

Brandl, K., & Schnabl, B. (2015) · Expert Review of Gastroenterology & Hepatology · doi:10.1586/17474124.2015.1057122 · Cited by 82 · see citing works

The intestinal immune system and gut barrier function in obesity and ageing

Shemtov, S. J., Emani, R., Bielska, O., Covarrubias, A. J., Verdin, E. M., Andersen, J. K., & Winer, D. A. (2022) · FEBS Journal · doi:10.1111/febs.16558 · Cited by 83 · see citing works

TGFβ Superfamily Members as Regulators of B Cell Development and Function—Implications for Autoimmunity

Tamayo, E., Álvarez, P., & Merino, R. (2018) · International Journal of Molecular Sciences · doi:10.3390/ijms19123928 · Cited by 80 · see citing works

Clinical significance of soluble immunoglobulins A and G and their coated bacteria in feces of patients with inflammatory bowel disease

Lin, R., Chen, H., Shu, W., Sun, M., Fang, L., Shi, Y., Pang, Z., Wu, W. H., & Liu, Z. (2018) · Journal of Translational Medicine · doi:10.1186/s12967-018-1723-0 · Cited by 78 · see citing works

Immunoglobulin A and liver diseases

Inamine, T., & Schnabl, B. (2018) · Journal of Gastroenterology · doi:10.1007/s00535-017-1400-8 · Cited by 76 · see citing works

A subset of follicular helper-like MAIT cells can provide B cell help and support antibody production in the mucosa

Jensen, O., Trivedi, S., Meier, J. D., Fairfax, K. C., Hale, J. S., & Leung, D. T. (2022) · Science Immunology · doi:10.1126/sciimmunol.abe8931 · Cited by 76 · see citing works

Contribution of Zinc and Zinc Transporters in the Pathogenesis of Inflammatory Bowel Diseases

Ohashi, W., & Fukada, T. (2019) · Journal of Immunology Research · doi:10.1155/2019/8396878 · Cited by 70 · see citing works

Fermented infant formula (with Bifidobacterium breve C50 and Streptococcus thermophilus O65) with prebiotic oligosaccharides is safe and modulates the gut microbiota towards a microbiota closer to that of breastfed infants

Béghin, L., Tims, S., Roelofs, M., Rougé, C., Oozeer, R., Rakza, T., Chirico, G., Roeselers, G., Knol, J., Rozé, J., et al. (2020) · Clinical Nutrition · doi:10.1016/j.clnu.2020.07.024 · Cited by 69 · see citing works

The role of oligosaccharides and polysaccharides of xylan and mannan in gut health of monogastric animals

Tiwari, U. P., Fleming, S. A., Rasheed, M. S. A., Jha, R., & Dilger, R. N. (2020) · Journal of Nutritional Science · doi:10.1017/jns.2020.14 · Cited by 68 · see citing works

Micro- and Nanoplastic-Mediated Pathophysiological Changes in Rodents, Rabbits, and Chickens: A Review

Banerjee, A., & Shelver, W. L. (2021) · Journal of Food Protection · doi:10.4315/jfp-21-117 · Cited by 68 · see citing works

How the gut microbiome regulates host immune responses to viral vaccines

Vlasova, A. N., Takanashi, S., Miyazaki, A., Rajashekara, G., & Saif, L. J. (2019) · Current Opinion in Virology · doi:10.1016/j.coviro.2019.05.001 · Cited by 67 · see citing works

Weaning causes a prolonged but transient change in immune gene expression in the intestine of piglets

de Groot, N., Fariñas, F., Cabrera-Gómez, C. G., Pallarés, F. J., & Ramis, G. (2021) · Journal of Animal Science · doi:10.1093/jas/skab065 · Cited by 67 · see citing works

Towards the future exploration of mucosal mRNA vaccines against emerging viral diseases; lessons from existing next-generation mucosal vaccine strategies

Hameed, S. A., Paul, S., Dellosa, G. K. Y., Jaraquemada, D., & Bello, M. B. (2022) · npj Vaccines · doi:10.1038/s41541-022-00485-x · Cited by 64 · see citing works

Ovotransferrin enhances intestinal immune response in cyclophosphamide-induced immunosuppressed mice

Zhu, G., Luo, J., Du, H., Jiang, Y., Tu, Y., Yao, Y., & Xu, M. (2018) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2018.08.058 · Cited by 65 · see citing works

Epithelial endoplasmic reticulum stress orchestrates a protective IgA response

Grootjans, J., Krupka, N., Hosomi, S., Matute, J. D., Hanley, T., Saveljeva, S., Gensollen, T., Heijmans, J., Li, H., Limenitakis, J. P., et al. (2019) · Science · doi:10.1126/science.aat7186 · Cited by 65 · see citing works

Vaccination against Salmonella Infection: the Mucosal Way

Gayet, R., Bioley, G., Rochereau, N., Paul, S., & Corthésy, B. (2017) · Microbiology and Molecular Biology Reviews · doi:10.1128/mmbr.00007-17 · Cited by 64 · see citing works

Accurate identification and quantification of commensal microbiota bound by host immunoglobulins

Jackson, M. A., Pearson, C. F., Ilott, N. E., Huus, K. E., Hegazy, A. N., Webber, J., Finlay, B. B., Macpherson, A. J., Powrie, F. M., & Lam, L. H. (2021) · Microbiome · doi:10.1186/s40168-020-00992-w · Cited by 61 · see citing works

Microbiota and Colorectal Cancer: From Gut to Bedside

Silva, M. G., Brunner, V., & Tschurtschenthaler, M. (2021) · Frontiers in Pharmacology · doi:10.3389/fphar.2021.760280 · Cited by 58 · see citing works

Lactobacillus rhamnosus GG supernatant enhance neonatal resistance to systemic Escherichia coli K1 infection by accelerating development of intestinal defense

He, X., Zeng, Q., Puthiyakunnon, S., Zeng, Z., Yang, W., Qiu, J., Du, L., Boddu, S., Wu, T., Cai, D., et al. (2017) · Scientific Reports · doi:10.1038/srep43305 · Cited by 54 · see citing works

Probiotic bacteria cell walls stimulate the activity of the intestinal epithelial cells and macrophage functionality

Lemme‐Dumit, J. M., Polti, M. A., Perdigón, G., & Galdeano, C. M. (2017) · Beneficial Microbes · doi:10.3920/bm2016.0220 · Cited by 52 · see citing works

Cruel to Be Kind: Epithelial, Microbial, and Immune Cell Interactions in Gastrointestinal Cancers

Shalapour, S., & Karin, M. (2020) · Annual Review of Immunology · doi:10.1146/annurev-immunol-082019-081656 · Cited by 51 · see citing works

The neglected brothers come of age: B cells and cancer

Shalapour, S., & Karin, M. (2021) · Seminars in Immunology · doi:10.1016/j.smim.2021.101479 · Cited by 49 · see citing works

NIK signaling axis regulates dendritic cell function in intestinal immunity and homeostasis

Jie, Z., Yang, J.-Y., Gu, M., Wang, H., Xie, X., Li, Y., Liu, T., Zhu, L., Shi, J., Zhang, L., et al. (2018) · Nature Immunology · doi:10.1038/s41590-018-0206-z · Cited by 50 · see citing works

Evaluation of a Solid Dispersion of Curcumin With Polyvinylpyrrolidone and Boric Acid Against Salmonella Enteritidis Infection and Intestinal Permeability in Broiler Chickens: A Pilot Study

Hernández‐Patlan, D., Solís-Cruz, B., Pontin, K. P., Latorre, J. D., Baxter, M. F. A., Hernández-Velasco, X., Merino-Guzmán, R., Méndez‐Albores, A., Hargis, B. M., López‐Arellano, R., et al. (2018) · Frontiers in Microbiology · doi:10.3389/fmicb.2018.01289 · Cited by 49 · see citing works

Noncoding RNA transcription alters chromosomal topology to promote isotype-specific class switch recombination

Rothschild, G., Zhang, W., Lim, J., Giri, P. K., Laffleur, B., Chen, Y., Fang, M., Chen, Y., Nair, L., Liu, Z., et al. (2020) · Science Immunology · doi:10.1126/sciimmunol.aay5864 · Cited by 47 · see citing works

Immunoglobulin A, an Active Liaison for Host-Microbiota Homeostasis

Abokor, A. A., McDaniel, G. H., Golonka, R. M., Campbell, C., BRAHMANDAM, S., Yeoh, B. S., Joe, B., Vijay–Kumar, M., & Saha, P. (2021) · Microorganisms · doi:10.3390/microorganisms9102117 · Cited by 48 · see citing works

A systematic review of gut‐immune‐brain mechanisms in Autism Spectrum Disorder

Azhari, A., Azizan, F., & Esposito, G. (2018) · Developmental Psychobiology · doi:10.1002/dev.21803 · Cited by 47 · see citing works

Immunoglobulin A antibody composition is sculpted to bind the self gut microbiome

Yang, C., Chen-Liaw, A., Spindler, M. P., Tortorella, D., Moran, T. M., Cerutti, A., & Faith, J. J. (2022) · Science Immunology · doi:10.1126/sciimmunol.abg3208 · Cited by 47 · see citing works

Fermented Astragalus and its metabolites regulate inflammatory status and gut microbiota to repair intestinal barrier damage in dextran sulfate sodium-induced ulcerative colitis

Li, J., Ma, Y., Li, X., Wang, Y., Huo, Z., Yang, L., Li, J., Yang, H., Zhang, Z., Yang, P., et al. (2022) · Frontiers in Nutrition · doi:10.3389/fnut.2022.1035912 · Cited by 46 · see citing works

αvβ8 integrin-expression by BATF3-dependent dendritic cells facilitates early IgA responses to Rotavirus

Nakawesi, J., This, S., Hütter, J., Boucard-Jourdin, M., Barateau, V., Muleta, K. G., Gooday, L. J., Thomsen, K., López, A. G., Ulmert, I., et al. (2020) · Mucosal Immunology · doi:10.1038/s41385-020-0276-8 · Cited by 44 · see citing works

Effect of yeast Saccharomyces cerevisiae supplementation on serum antioxidant capacity, mucosal sIgA secretions and gut microbial populations in weaned piglets

Zhu, C., Li, W. A. N. G., Shao-yong, W. E. I., Chen, Z., Ma, X., ZHENG, C.-T., & Jiang, Z. (2017) · Journal of Integrative Agriculture · doi:10.1016/s2095-3119(16)61581-2 · Cited by 44 · see citing works

Identification of Serum Biomarkers for Intestinal Integrity in a Broiler Chicken Malabsorption Model

Baxter, M. F. A., Latorre, J. D., Dridi, S., Merino-Guzmán, R., Hernández-Velasco, X., Hargis, B. M., & Téllez‐Isaías, G. (2019) · Frontiers in Veterinary Science · doi:10.3389/fvets.2019.00144 · Cited by 43 · see citing works

An Insight into Probiotics Bio-Route: Translocation from the Mother’s Gut to the Mammary Gland

Selvamani, S., Dailin, D. J., Gupta, V. K., Wahid, M., Keat, H. C., Natasya, K. H., Malek, R. A., Haque, S., Sayyed, R. Z., Abomoelak, B., et al. (2021) · Applied Sciences · doi:10.3390/app11167247 · Cited by 42 · see citing works

Invited Review: Ruminal microbes, microbial products, and systemic inflammation

Garcia, M., Bradford, B. J., & Nagaraja, T. G. (2017) · The Professional Animal Scientist · doi:10.15232/pas.2017-01663 · Cited by 41 · see citing works

Early supplementation of Saccharomyces cerevisiae boulardii CNCM I-1079 in newborn dairy calves increases IgA production in the intestine at 1 week of age

Villot, C., Chen, Y., Pedgerachny, K., Chaucheyras‐Durand, F., Chevaux, E., Skidmore, A. L., Guan, L. L., & Steele, M. A. (2020) · Journal of Dairy Science · doi:10.3168/jds.2020-18274 · Cited by 41 · see citing works

Recent Advances in Gut‐ and Gut–Organ‐Axis‐on‐a‐Chip Models

Kim, R., & Sung, J. H. (2024) · Advanced Healthcare Materials · doi:10.1002/adhm.202302777 · Cited by 42 · see citing works

Emerging role of nutritional short-chain fatty acids (SCFAs) against cancer via modulation of hematopoiesis

Thiruvengadam, M., Subramanian, U., Venkidasamy, B., Thirupathi, P., Samynathan, R., Shariati, M. A., Ребезов, М. Б., Chung, I., & Rengasamy, K. R. R. (2021) · Critical Reviews in Food Science and Nutrition · doi:10.1080/10408398.2021.1954874 · Cited by 40 · see citing works

Nutrient Sensing in CD11c Cells Alters the Gut Microbiota to Regulate Food Intake and Body Mass

Chagwedera, D. N., Ang, Q. Y., Bisanz, J. E., Leong, Y. A., Ganeshan, K., Cai, J., Patterson, A. D., Turnbaugh, P. J., & Chawla, A. (2019) · Cell Metabolism · doi:10.1016/j.cmet.2019.05.002 · Cited by 38 · see citing works

Host innate and adaptive immunity shapes the gut microbiota biogeography

Gu, M., Samuelson, D. R., de la Rúa, N. M., Charles, T. P., Taylor, C. M., Luo, M., Siggins, R. W., Shellito, J. E., & Welsh, D. A. (2022) · Microbiology and Immunology · doi:10.1111/1348-0421.12963 · Cited by 36 · see citing works

Metabolic changes during B cell differentiation for the production of intestinal IgA antibody

Kunisawa, J. (2016) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-016-2414-8 · Cited by 38 · see citing works

Polymeric immunoglobulin receptor deficiency exacerbates autoimmune hepatitis by inducing intestinal dysbiosis and barrier dysfunction

Lin, H., Lin, J., Pan, T., Li, T., Jiang, H., Fang, Y., Wang, Y., Wu, F.-L., Huang, J. M., Zhang, H., et al. (2023) · Cell Death and Disease · doi:10.1038/s41419-023-05589-3 · Cited by 37 · see citing works

Berberis lycium fruit extract attenuates oxi-inflammatory stress and promotes mucosal healing by mitigating NF-κB/c-Jun/MAPKs signalling and augmenting splenic Treg proliferation in a murine model of dextran sulphate sodium-induced ulcerative colitis

Sharma, A., Tirpude, N. V., Kulurkar, P. M., Sharma, R., & Padwad, Y. S. (2019) · European Journal of Nutrition · doi:10.1007/s00394-019-02114-1 · Cited by 37 · see citing works

Interaction between IgA and gut microbiota and its role in controlling metabolic syndrome

Guo, J., Han, X., Huang, W., You, Y., & Zhan, J. (2020) · Obesity Reviews · doi:10.1111/obr.13155 · Cited by 37 · see citing works

Stress, inflammation, microbiome and depression

Medina-Rodriguez, E. M., Cruz, A. A., Abreu, J. C. D., & Beurel, E. (2023) · Pharmacology Biochemistry and Behavior · doi:10.1016/j.pbb.2023.173561 · Cited by 37 · see citing works

Antigen-Specific Mucosal Immunity Regulates Development of Intestinal Bacteria-Mediated Diseases

Fujimoto, K., Kawaguchi, Y., Shimohigoshi, M., Gotoh, Y., Nakano, Y., Usui, Y., Hayashi, T., Kimura, Y., Uematsu, M., Yamamoto, T., et al. (2019) · Gastroenterology · doi:10.1053/j.gastro.2019.08.021 · Cited by 36 · see citing works

Oral delivery of tumor microparticle vaccines activates NOD2 signaling pathway in ileac epithelium rendering potent antitumor T cell immunity

Dong, W., Zhang, H., Yin, X., Liu, Y., Chen, D., Liang, X., Jin, X., Lv, J., Ma, J., Tang, K., et al. (2017) · OncoImmunology · doi:10.1080/2162402x.2017.1282589 · Cited by 35 · see citing works

The Biology of Intestinal Immunoglobulin A Responses

Cerutti, A., & Rescigno, M. (2008) · Immunity · doi:10.1016/j.immuni.2008.05.001 · Cited by 548 · see citing works

Dynamic interactions between bacteria and immune cells leading to intestinal IgA synthesis

Tsuji, M., Suzuki, K., Kinoshita, K., & Fagarasan, S. (2008) · Seminars in Immunology · doi:10.1016/j.smim.2007.12.003 · Cited by 77 · see citing works

Reciprocal regulation of IgA and the gut microbiota: a key mutualism in the intestine

Takeuchi, T., & Ohno, H. (2021) · International Immunology · doi:10.1093/intimm/dxab049 · Cited by 33 · see citing works

Microbiota-antibody interactions that regulate gut homeostasis

Weis, A. M., & Round, J. L. (2021) · Cell Host & Microbe · doi:10.1016/j.chom.2021.02.009 · Cited by 112 · see citing works

Functional flexibility of intestinal IgA - broadening the fine line

Slack, E. M. C., Balmer, M. L., Fritz, J. H., & Hapfelmeier, S. (2012) · Open Access CRIS of the University of Bern · doi:10.7892/boris.16027