Cited by 960Mindfulness and Compassion InterventionsPsychological Well-being and Life SatisfactionReligion, Spirituality, and Psychology

The DOI matches its Crossref record; 74 of the 74 references it cites were found in a registry or an index; none of the 68 sources its claims cite is checked for support yet.

Loving-kindness and compassion meditation: Potential for psychological interventions

Open access
Hofmann, Stefan G., Grossman, Paul, Hinton, Devon E.·2011·Clinical Psychology Review

Abstract

Mindfulness-based meditation interventions have become increasingly popular in contemporary psychology. Other closely related meditation practices include loving-kindness meditation (LKM) and compassion meditation (CM), exercises oriented toward enhancing unconditional, positive emotional states of kindness and compassion. This article provides a review of the background, the techniques, and the empirical contemporary literature of LKM and CM. The literature suggests that LKM and CM are associated with an increase in positive affect and a decrease in negative affect. Preliminary findings from neuroendocrine studies indicate that CM may reduce stress-induced subjective distress and immune response. Neuroimaging studies suggest that LKM and CM may enhance activation of brain areas that are involved in emotional processing and empathy. Finally, preliminary intervention studies support application of these strategies in clinical populations. It is concluded that, when combined with empirically supported treatments, such as cognitive behavioral therapy, LKM and CM may provide potentially useful strategies for targeting a variety of different psychological problems that involve interpersonal processes, such as social anxiety, marital conflict, anger, and coping with the strains of long-term caregiving.

Overview

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TL;DR

This narrative review summarizes background, techniques, and empirical literature on loving-kindness meditation (LKM) and compassion meditation (CM), suggesting they may increase positive affect and decrease negative affect. Preliminary evidence supports their use as adjuncts to empirically supported treatments for interpersonal and stress-related problems, but the literature is small and methodologically limited.

Key findings

  • LKM and CM are associated with increases in positive affect and decreases in negative affect; preliminary neuroendocrine studies suggest CM may reduce stress-induced subjective distress and immune response, and neuroimaging studies suggest they may enhance activation of brain areas involved in emotional processing and empathy.
  • Hutcherson et al. (2008) randomized 93 participants to LKM (n = 45) or imagery (n = 48); a brief 7-minute LKM exercise produced small to moderate changes in explicit and implicit positivity toward neutral strangers and the self.
  • Fredrickson et al. (2008) assigned employees to LKM (n = 102) or waitlist control (n = 100) in six 60-minute group sessions over 7 weeks; LKM increased a range of positive emotions and personal resources and reduced depressive symptoms, but effects were small and negative emotions did not substantially change.
  • Carson et al. (2005) compared 8-week LKM (n = 18) with standard care (n = 25) for chronic low back pain and found greater reductions in pain, anger, and psychological distress; Pace et al. (2009) randomized healthy adults to 6 weeks of CM (n = 33) or health discussions (n = 28) and found increased meditation practice was associated with decreased stress-induced interleukin-6 and subjective distress, though groups did not differ in plasma cortisol or interleukin-6.

Methods

  • Narrative review of the historical background, therapeutic techniques, and contemporary empirical literature on LKM and CM, including experimental, neuroendocrine, neuroimaging, and preliminary intervention studies.
  • The review synthesizes cited studies with varied designs and samples, such as randomized experiments, waitlist or standard-care comparisons, and small clinical pilot trials.
  • Main analysis is qualitative synthesis; no formal meta-analysis or new primary data collection is reported.

Limitations

  • The paper states that the research literature is small, empirical evidence is naturally limited, findings are very preliminary and should be evaluated with great caution, and there is remarkable variation in the techniques used across studies.
  • The paper notes specific limitations in cited studies: Pace et al. (2009) administered the stress test after rather than before CM training, and both Pace studies had problematic active control conditions; Gilbert and Procter (2006) lacked a standard diagnostic assessment; Mayhew and Gilbert (2008) had a small sample, high dropout, poorly controlled design, and inadequate assessment methods.
  • The paper also observes that comparing very short-term LKM with long-term training may be inappropriate because different mechanisms may be activated, and that Fredrickson et al. (2008) found no treatment benefits for reducing negative emotions, suggesting LKM and CM may require integration with mindfulness practices.

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Integrity signals

Registry

Crossref · 10.1016/j.cpr.2011.07.003

Cites

74 of 74 references verified0 citation errors · 0 not checkable

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Claims the paper makes

51 Not checked yet · 15 Own interpretation · 4 No basis given

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Show all 36 claims

  • It may state two separate claims as one. 22
  • Probably not a substantial claim. 14
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  • The authors state this as an assumption.

    By mindfully investigating what occurs when one attempts to generate loving-kindness or compassion, insight is gained into the nature of these emotions themselves, as well as one’s personal relationships to them.

    “Rather, by mindfully investigating what occurs when one attempts to generate loving-kindness or compassion, it is presumed that insight is gained into the nature of these emotions themselves, as well as one’s personal relationships to them.”
  • The authors state this as an assumption.

    Turning toward the focus of experience in a kind, open, patient and tolerant manner causes a shift in affective states toward greater loving-kindness and compassion.

    “Also by turning toward this focus of experience in a kind, open, patient and tolerant manner, a shift in these affective states toward greater loving-kindness and compassion is thought to take place.”
  • The paper relies on this without support.

    In the Buddhist tradition, LKM and CM have traditionally been combined with other meditation practices such as multi-sensorial mindfulness.

    “In the Buddhist tradition, LKM and CM have traditionally been combined with other meditation practices—such as multi-sensorial mindfulness--and may well be efficacious techniques when added to existing empirically supported therapies, such as cognitive behavioral treatments.”
  • The paper relies on this without support.

    The insula is important in detecting emotions and in mapping physiological symptoms to emotions and making this information available to other parts of the brain.

    “The insula is important in detecting emotions and in mapping physiological symptoms to emotions (such as heart rate) and to make this information available to other parts of the brain.”
  • The paper relies on this without support.

    The amygdala is crucial for processing emotional stimuli, and the right temporal parietal juncture is implicated in empathy and perceiving mental and emotional states of others.

    “Furthermore, meditation increased activity in the amygdala, which is crucial for the processing of emotional stimuli, and in the right temporal parietal juncture, an area that is implicated in empathy and when perceiving mental and emotional states of others.”
  • The authors state this as an assumption.

    LKM and CM abilities take considerable time and practice to develop.

    “Examining the effects of these practices in a laboratory by giving brief instructions to novices goes against the very basic Buddhist assumption that these abilities take considerable time and practice to develop (see Grossman, 2010).”
  • The paper relies on this without support.

    The Buddhist tradition conceptualizes metta and karuna as the two brahma viharas that are incompatible with anger, hatred, envy, and jealousy.

    “The Buddhist tradition conceptualizes metta and karuna as being the two brahma viharas that are incompatible with anger, hatred, envy, and jealousy.”
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Citations

Cites

Research works printed but not linked: 2

  1. Grossman, P. (in press). Defining mindfulness by “how poorly I think I pay attention during everyday awareness” and other intractable problems for psychology's (re)invention of mindfulness. Psychological Assessment.
  2. Hinton, D. E., Pich, V., Nickerson, A., Hofmann, S. G., & Otto, M. W. (in press). Mindfulness and acceptance techniques as applied to refugee and ethnic minority populations: Examples from culturally adapted CBT (CA-CBT). Cognitive and Behavioral Practice.

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Metadata

Authors
Hofmann, S. G., Grossman, P., & Hinton, D. E.
Affiliations
  • Boston University (US)
  • University Hospital of Basel (CH)
  • Harvard University (US)
Corresponding author
Hofmann, Stefan G.
Venue
Clinical Psychology Review
Publisher
Elsevier BV
Published
2011-11
Volume
31
Issue
7
Pages
1126-1132
ISSN
0272-7358 (ISSN-L)
OpenAlex
W2145585447
Cited by
960
References
71
Citations by year
2026: 51 · 2025: 82 · 2024: 69 · 2023: 66 · 2022: 83 · 2021: 65 · 2020: 86 · 2019: 69 · 2018: 64 · 2017: 72 · 2016: 61 · 2015: 51 · 2014: 77 · 2013: 39 · 2012: 19
FWCI
6.70
Type
journal article
Language
en
Open access
Locations
  • Clinical Psychology Review (publishedVersion)
  • PubMed (publishedVersion)
  • PubMed Central (acceptedVersion)
Funders
National Institute of Mental Health (R01MH078308)
Topics
  • Social Sciences › Psychology › Clinical Psychology › Mindfulness and Compassion Interventions
  • Social Sciences › Psychology › Social Psychology › Psychological Well-being and Life Satisfaction
  • Social Sciences › Health › Religion, Spirituality, and Psychology
Keywords
loving-kindness meditation, compassion meditation, mindfulness-based interventions, positive affect, negative affect, stress response, immune response, neuroendocrine effects, brain activation, empathy, cognitive behavioral therapy, depression, social anxiety, marital conflict, anger, caregiving stress
MeSH terms
Adaptation, Psychological, Empathy, Humans, Love, Meditation

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