SoxD Proteins Influence Multiple Stages of Oligodendrocyte Development and Modulate SoxE Protein Function

Disruption of the glucocorticoid receptor gene in the nervous system results in reduced anxiety

Tronche, F., Kellendonk, C., Kretz, O., Gass, P., Anlag, K., Orban, P. C., Bock, R., Klein, R., & Schütz, G. (1999) · Nature Genetics · doi:10.1038/12703 · Cited by 1,841 · see citing works

The transcription factor Sox9 has essential roles in successive steps of the chondrocyte differentiation pathway and is required for expression of <i>Sox5</i> and <i>Sox6</i>

Akiyama, H., Chaboissier, M.-C., Martin, J. F., Schedl, A., & de Crombrugghe, B. (2002) · Genes &amp; Development · doi:10.1101/gad.1017802 · Cited by 1,721 · see citing works

Competing waves of oligodendrocytes in the forebrain and postnatal elimination of an embryonic lineage

Kessaris, N., Fogarty, M., Iannarelli, P., Grist, M., Wegner, M., & Richardson, W. D. (2006) · Nature Neuroscience · doi:10.1038/nn1620 · Cited by 1,195 · see citing works

SOX9 Is a Potent Activator of the Chondrocyte-Specific Enhancer of the Proα1(II) Collagen Gene

Lefebvre, V., Huang, W., Harley, V. R., Goodfellow, P. N., & Crombrugghe, B. D. (1997) · Molecular and Cellular Biology · doi:10.1128/mcb.17.4.2336 · Cited by 1,077 · see citing works

The transcription factor Sox10 is a key regulator of peripheral glial developmentPreprint

Britsch, S., Goerich, D. E., Riethmacher, D., Peirano, R. I., Rossner, M. J., Nave, K., Birchmeier, C., & Wegner, M. (2001) · Genes & Development · doi:10.1101/gad.186601 · Cited by 915 · see citing works

Vertebrate neurogenesis is counteracted by Sox1–3 activity

Bylund, M., Andersson, E., Novitch, B. G., & Muhr, J. (2003) · Nature Neuroscience · doi:10.1038/nn1131 · Cited by 825 · see citing works

A new long form of Sox5 (L‐Sox5), Sox6 and Sox9 are coexpressed in chondrogenesis and cooperatively activate the type II collagen gene

Lefebvre, V., Li, P., & de Crombrugghe, B. (1998) · The EMBO Journal · doi:10.1093/emboj/17.19.5718 · Cited by 811 · see citing works

Sox10, a Novel Transcriptional Modulator in Glial Cells

Kuhlbrodt, K., Herbarth, B., Sock, E., Hermans-Borgmeyer, I., & Wegner, M. (1998) · The Journal of Neuroscience · doi:10.1523/jneurosci.18-01-00237.1998 · Cited by 781 · see citing works

Terminal differentiation of myelin-forming oligodendrocytes depends on the transcription factor Sox10Preprint

Stolt, C. C., Rehberg, S., Ader, M., Lommes, P., Riethmacher, D., Schachner, M., Bartsch, U., & Wegner, M. (2002) · Genes & Development · doi:10.1101/gad.215802 · Cited by 685 · see citing works

The Sox9 transcription factor determines glial fate choice in the developing spinal cord

Stolt, C. C., Lommes, P., Sock, E., Chaboissier, M.-C., Schedl, A., & Wegner, M. (2003) · Genes &amp; Development · doi:10.1101/gad.259003 · Cited by 636 · see citing works

The Transcription Factors L-Sox5 and Sox6 Are Essential for Cartilage Formation

Smits, P. J., Li, P., Mandel, J., Zhang, Z., Deng, J. M., Behringer, R. R., Crombrugghe, B. D., & Lefèbvre, V. (2001) · Developmental Cell · doi:10.1016/s1534-5807(01)00003-x · Cited by 600 · see citing works

Neural crest origins of the neck and shoulder

Matsuoka, T., Ahlberg, P., Kessaris, N., Iannarelli, P., Dennehy, U., Richardson, W. D., McMahon, A. P., & Koentges, G. (2005) · Nature · doi:10.1038/nature03837 · Cited by 525 · see citing works

From stem cells to neurons and glia: a Soxist's view of neural development

Wegner, M., & Stolt, C. C. (2005) · Trends in Neurosciences · doi:10.1016/j.tins.2005.08.008 · Cited by 426 · see citing works

Lbx1 specifies somatosensory association interneurons in the dorsal spinal cord

Gross, M. K., Dottori, M., & Goulding, M. (2002) · Neuron · doi:10.1016/s0896-6273(02)00690-6 · Cited by 396 · see citing works

Oligodendrocyte wars

Richardson, W. D., Kessaris, N., & Pringle, N. (2006) · Nature reviews. Neuroscience · doi:10.1038/nrn1826 · Cited by 385 · see citing works

The homeodomain factor Lbx1 distinguishes two major programs of neuronal differentiation in the dorsal spinal cord

Müller, T., Brohmann, H., Pierani, A., Heppenstall, P. A., Lewin, G. R., Jessell, T. M., & Birchmeier, C. (2002) · Neuron · doi:10.1016/s0896-6273(02)00689-x · Cited by 368 · see citing works

L-Sox5, Sox6 and Sox9 control essential steps of the chondrocyte differentiation pathway

Lefebvre, V., Behringer, R. R., & Crombrugghe, B. D. (2001) · Osteoarthritis and Cartilage · doi:10.1053/joca.2001.0447 · Cited by 367 · see citing works

Multiple dorsoventral origins of oligodendrocyte generation in the spinal cord and hindbrain.

Vallstedt, A., Klos, J. M., & Ericson, J. (2005) · Neuron · doi:10.1016/j.neuron.2004.12.026 · Cited by 346 · see citing works

Generation of oligodendrocyte precursor cells from mouse dorsal spinal cord independent of Nkx6 regulation and Shh signaling.

Cai, J., Qi, Y., Hu, X.-M., Tan, M., Liu, Z., Zhang, J.-S., Li, Q., Sander, M., & Qiu, M.-S. (2005) · Neuron · doi:10.1016/j.neuron.2004.12.028 · Cited by 345 · see citing works

The polysialic acid modification of the neural cell adhesion molecule is involved in spatial learning and hippocampal long-term potentiation

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Transcriptional Regulation of Cortical Neuron Migration by POU Domain Factors

McEvilly, R. J., de Diaz, M. O., Schonemann, M. D., Hooshmand, F., & Rosenfeld, M. G. (2002) · Science · doi:10.1126/science.1067132 · Cited by 271 · see citing works

A subset of oligodendrocytes generated from radial glia in the dorsal spinal cord

Fogarty, M., Richardson, W., & Kessaris, N. (2005) · Development · doi:10.1242/dev.01777 · Cited by 270 · see citing works

Protein Zero Gene Expression Is Regulated by the Glial Transcription Factor Sox10

Peirano, R., Goerich, D. E., Riethmacher, D., & Wegner, M. (2000) · Molecular and Cellular Biology · doi:10.1128/mcb.20.9.3198-3209.2000 · Cited by 227 · see citing works

Olig2 and Ngn2 function in opposition to modulate gene expression in motor neuron progenitor cells.Preprint

Lee, S.-K., Lee, B., Ruiz, E. C., & Pfaff, S. (2005) · Genes & Development · doi:10.1101/gad.1257105 · Cited by 226 · see citing works

Sox21 promotes the progression of vertebrate neurogenesis

Sandberg, M., Källström, M., & Muhr, J. (2005) · Nature Neuroscience · doi:10.1038/nn1493 · Cited by 210 · see citing works

Transcription factors Sox8 and Sox10 perform non-equivalent roles during oligodendrocyte development despite functional redundancy

Stolt, C., Lommes, P., Friedrich, R., & Wegner, M. (2004) · Development · doi:10.1242/dev.01114 · Cited by 204 · see citing works

Lbx1 and Tlx3 are opposing switches in determining GABAergic versus glutamatergic transmitter phenotypes

Cheng, L., Samad, O. A., Xu, Y., Mizuguchi, R., Luo, P., Shirasawa, S., Goulding, M., & Ma, Q. (2005) · Nature Neuroscience · doi:10.1038/nn1569 · Cited by 198 · see citing works

Idiopathic Weight Reduction in Mice Deficient in the High-Mobility-Group Transcription Factor Sox8

Sock, E., Schmidt, K., Hermanns-Borgmeyer, I., Bösl, M. R., & Wegner, M. (2001) · Molecular and Cellular Biology · doi:10.1128/mcb.21.20.6951-6959.2001 · Cited by 176 · see citing works

Functional equivalence of the transcription factors Pax2 and Pax5 in mouse development

Bouchard, M., Pfeffer, P., & Busslinger, M. (2000) · Development · doi:10.1242/dev.127.17.3703 · Cited by 165 · see citing works

The high-mobility-group domain of Sox proteins interacts with DNA-binding domains of many transcription factors

Wissmuller, S. (2006) · Nucleic Acids Research · doi:10.1093/nar/gkl105 · Cited by 160 · see citing works

Loss of DNA-dependent dimerization of the transcription factor SOX9 as a cause for campomelic dysplasia

Sock, E. (2003) · Human Molecular Genetics · doi:10.1093/hmg/ddg158 · Cited by 142 · see citing works

Functional Analysis of Sox10 Mutations Found in Human Waardenburg-Hirschsprung Patients

Kuhlbrodt, K., Schmidt, C. S., Sock, E., Pingault, V., Bondurand, N., Goossens, M., & Wegner, M. (1998) · Journal of Biological Chemistry · doi:10.1074/jbc.273.36.23033 · Cited by 139 · see citing works

LSox5 regulates RhoB expression in the neural tube and promotes generation of the neural crest

Pérez‐Alcalá, S., Nieto, M. A., & Barbas, J. A. (2004) · Development · doi:10.1242/dev.01329 · Cited by 112 · see citing works

Impact of transcription factor Sox8 on oligodendrocyte specification in the mouse embryonic spinal cord

Stolt, C. C., Schmitt, S., Lommes, P., Sock, E., & Wegner, M. (2005) · Developmental Biology · doi:10.1016/j.ydbio.2005.03.010 · Cited by 105 · see citing works

Generation of mice harboring a Sox4 conditional null allele

Penzo‐Méndez, A., Dy, P., Bhattaram, P., & Lefèbvre, V. (2007) · genesis · doi:10.1002/dvg.20358 · Cited by 104 · see citing works

Reciprocal gene replacements reveal unique functions for Phox2 genes during neural differentiation

Coppola, E., Pattyn, A., Guthrie, S., Goridis, C., & Studer, M. (2005) · The EMBO Journal · doi:10.1038/sj.emboj.7600897 · Cited by 86 · see citing works

SOX6 binds CtBP2 to repress transcription from the Fgf-3 promoter

Murakami, A. (2001) · Nucleic Acids Research · doi:10.1093/nar/29.16.3347 · Cited by 79 · see citing works

Oligodendroglial-specific Transcriptional Factor SOX10 is Ubiquitously Expressed in Human Gliomas

Bannykh, S., Stolt, C., Kim, J., Perry, A., & Wegner, M. (2005) · Journal of Neuro-Oncology · doi:10.1007/s11060-005-5533-x · Cited by 73 · see citing works

Identification of a human glioma antigen, SOX6, recognized by patients' sera

Ueda, R., Iizuka, Y., Yoshida, K., et al. (2003) · Oncogene · doi:10.1038/sj.onc.1207252 · Cited by 67 · see citing works

Expression of Connexin47 in Oligodendrocytes is Regulated by the Sox10 Transcription Factor

Schlierf, B., Werner, T., Glaser, G., & Wegner, M. (2006) · Journal of Molecular Biology · doi:10.1016/j.jmb.2006.05.072 · Cited by 61 · see citing works

The O-2Aadult progenitor cell: a glial stem cell of the adult central nervous system

Noble, M., Wren, D. R., & Wolswijk, G. (1992) · Seminars in Cell Biology · doi:10.1016/1043-4682(92)90012-k · Cited by 56 · see citing works

Toward understanding the functions of the two highly related Sox5 and Sox6 genes

Lefèbvre, V. (2002) · Journal of Bone and Mineral Metabolism · doi:10.1007/s007740200017 · Cited by 48 · see citing works

Generation of mice harboring a Sox6 conditional null allele

Dumitriu, B., Dy, P., Smits, P. J., & Lefebvre, V. (2006) · genesis · doi:10.1002/dvg.20210 · Cited by 35 · see citing works

Immunohistochemical analysis of SOX6 expression in human brain tumors

Ueda, R., Yoshida, K., Kawakami, Y., et al. (2004) · Brain Tumor Pathology · doi:10.1007/bf02482186 · Cited by 24 · see citing works

Oligodendrocyte heterogeneity in the mouse juvenile and adult central nervous system

Marques, S., Zeisel, A., Codeluppi, S., van Bruggen, D., Mendanha Falcão, A., Xiao, L., Li, H., Häring, M., Hochgerner, H., Romanov, R. A., et al. (2016) · Science · doi:10.1126/science.aaf6463 · Cited by 1,246 · see citing works

Brain cell type–specific enhancer–promoter interactome maps and disease <b>-</b> risk association

Nott, A., Holtman, I. R., Coufal, N. G., Schlachetzki, J. C. M., Yu, M., Hu, R., Han, C. Z., Pena, M., Xiao, J., Wu, Y., et al. (2019) · Science · doi:10.1126/science.aay0793 · Cited by 823 · see citing works

Oligodendrocyte-Encoded HIF Function Couples Postnatal Myelination and White Matter Angiogenesis

Yuen, T. J., Silbereis, J. C., Griveau, A., Chang, S. M., Daneman, R., Fancy, S. P. J., Zahed, H., Maltepe, E., & Rowitch, D. H. (2014) · Cell · doi:10.1016/j.cell.2014.04.052 · Cited by 433 · see citing works

SOX5 postmitotically regulates migration, postmigratory differentiation, and projections of subplate and deep-layer neocortical neurons

Kwan, K. Y., Lam, M. M. S., Krsnik, Ž., Kawasawa, Y. I., Lefebvre, V., & Šestan, N. (2008) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0806791105 · Cited by 271 · see citing works

The Cell-Intrinsic Requirement of Sox6 for Cortical Interneuron Development

Batista-Brito, R., Rossignol, E., Hjerling-Leffler, J., Denaxa, M., Wegner, M., Lefebvre, V., Pachnis, V., & Fishell, G. (2009) · Neuron · doi:10.1016/j.neuron.2009.08.005 · Cited by 214 · see citing works

MicroRNA-21 down-regulates the expression of tumor suppressor PDCD4 in human glioblastoma cell T98G

Chen, Y., Liu, W., Chao, T., Zhang, Y., Yan, X., Gong, Y., Qiang, B., Yuan, J., Sun, M., & Peng, X. (2008) · Cancer Letters · doi:10.1016/j.canlet.2008.06.034 · Cited by 217 · see citing works

A unique role for DNA (hydroxy)methylation in epigenetic regulation of human inhibitory neurons

Kozlenkov, A., Li, J., Apontes, P., Hurd, Y. L., Byne, W. M., Koonin, E. V., Wegner, M., Mukamel, E. A., & Dracheva, S. (2018) · Science Advances · doi:10.1126/sciadv.aau6190 · Cited by 103 · see citing works

Evolution of regulatory signatures in primate cortical neurons at cell-type resolution

Kozlenkov, A., Vermunt, M. W., Apontes, P., Li, J., Hao, K., Sherwood, C. C., Hof, P. R., Ely, J. J., Wegner, M., Mukamel, E. A., et al. (2020) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2011884117 · Cited by 30 · see citing works

Overexpression of miR-219 promotes differentiation of human induced pluripotent stem cells into pre-oligodendrocyte

Nazari, B., Soleimani, M., Ebrahimi-Barough, S., Enderami, S. E., Kazemi, M., Negahdari, B., Sadroddiny, E., & Ai, J. (2018) · Journal of Chemical Neuroanatomy · doi:10.1016/j.jchemneu.2018.03.001 · Cited by 24 · see citing works

Extracellular and intracellular regulation of oligodendrocyte development: Roles of Sonic hedgehog and expression of E proteins

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Oligodendrocyte-lineage cell exocytosis and L-type prostaglandin D synthase promote oligodendrocyte development and myelinationPreprint

Pan, L., Trimarco, A., Zhang, A. J., et al. (2022) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2022.02.14.480339 · Cited by 4 · see citing works

Oligodendrocyte-lineage cell exocytosis and L-type prostaglandin D synthase promote oligodendrocyte development and myelination

Pan, L., Trimarco, A., Zhang, A. J., Fujimori, K., Urade, Y., Sun, L. O., Taveggia, C., & Zhang, Y. (2023) · eLife · doi:10.7554/elife.77441 · Cited by 31 · see citing works

Regulation of oligodendrocyte development

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m6A mRNA methylation is essential for oligodendrocyte maturation and CNS myelination

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