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VARP Is Recruited on to Endosomes by Direct Interaction with Retromer, Where Together They Function in Export to the Cell Surface

Hesketh, Geoffrey G., Pérez-Dorado, Inmaculada, Jackson, Lauren P., Wartosch, Lena, Schäfer, Ingmar B., Gray, Sally R., McCoy, Airlie J., Zeldin, Oliver B., Garman, Elspeth F., Harbour, Michael E., Evans, Philip R., Seaman, Matthew N.J., Luzio, J. Paul, Owen, David J.·2014·Developmental Cell
DOI 10.1016/j.devcel.2014.04.010PMC PMC4059916
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  • The Retromer sub-domain proximity proteome included the RAB7 GAP TBC1D5, the RAB21/RAB32/RAB38 GEF VARP, and the RAB10 GEFs DENND4A and DENND4C.

    “These included known Retromer accessory proteins, the RAB7 GAP TBC1D546,77–81, the RAB21/RAB32/RAB38 GEF VARP (a.k.a. ANKRD27)47,48,82, and the RAB10 GEFs DENND4A and DENND4C83,84.”

    From Mapping of endosomal proximity proteomes reveals Retromer as a hub for RAB GTPase regulation (2025) · cites this paper as [47]

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Metadata

Authors
Hesketh, G. G., Pérez-Dorado, I., Jackson, L. P., Wartosch, L., Schäfer, I. B., Gray, S. R., McCoy, A. J., Zeldin, O. B., Garman, E. F., Harbour, M. E., Evans, P. R., Seaman, M. N. J., Luzio, J. P., & Owen, D. J.
Venue
Developmental Cell
Publisher
Elsevier BV
Published
2014-06
Volume
29
Issue
5
Pages
591-606
ISSN
1534-5807
DOI
10.1016/j.devcel.2014.04.010
PMC
PMC4059916
Cited by
136
References
1
Language
en
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