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Role of the mammalian retromer in sorting of the cation-independent mannose 6-phosphate receptor

Arighi, Cecilia N., Hartnell, Lisa M., Aguilar, Ruben C., Haft, Carol R., Bonifacino, Juan S.·2004·The Journal of Cell Biology
DOI 10.1083/jcb.200312055PMC PMC2172094
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Abstract

The cation-independent mannose 6-phosphate receptor (CI-MPR) mediates sorting of lysosomal hydrolase precursors from the TGN to endosomes. After releasing the hydrolase precursors into the endosomal lumen, the unoccupied receptor returns to the TGN for further rounds of sorting. Here, we show that the mammalian retromer complex participates in this retrieval pathway. The hVps35 subunit of retromer interacts with the cytosolic domain of the CI-MPR. This interaction probably occurs in an endosomal compartment, where most of the retromer is localized. In particular, retromer is associated with tubular–vesicular profiles that emanate from early endosomes or from intermediates in the maturation from early to late endosomes. Depletion of retromer by RNA interference increases the lysosomal turnover of the CI-MPR, decreases cellular levels of lysosomal hydrolases, and causes swelling of lysosomes. These observations indicate that retromer prevents the delivery of the CI-MPR to lysosomes, probably by sequestration into endosome-derived tubules from where the receptor returns to the TGN.

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Research works printed but not linked: 74

  1. 2002, J. Cell Biol., 156, 511, 10.1083/jcb.200109030 · DOI
  2. 1997, Mol. Biol. Cell., 8, 1261, 10.1091/mbc.8.7.1261 · DOI
  3. 2002, EMBO J., 21, 2557, 10.1093/emboj/21.11.2557 · DOI · Paper page
  4. 1993, J. Biol. Chem., 268, 22338, 10.1016/S0021-9258(18)41533-5 · DOI
  5. 1997, J. Biol. Chem., 272, 7003, 10.1074/jbc.272.11.7003 · DOI
  6. 1996, J. Cell Biol., 133, 529, 10.1083/jcb.133.3.529 · DOI
  7. 2001, Mol. Biol. Cell., 12, 1885, 10.1091/mbc.12.6.1885 · DOI
  8. 1983, Biochem. J., 214, 353, 10.1042/bj2140353 · DOI
  9. 2000, J. Cell Biol., 149, 81, 10.1083/jcb.149.1.81 · DOI · Paper page
  10. 2001, Mol. Biol. Cell., 12, 475, 10.1091/mbc.12.2.475 · DOI
  11. 1998, Cell., 93, 433, 10.1016/S0092-8674(00)81171-X · DOI
  12. 1994, J. Biol. Chem., 269, 12159, 10.1016/S0021-9258(17)32695-9 · DOI
  13. 2002, Science., 297, 1700, 10.1126/science.1075327 · DOI · Paper page
  14. 1983, Eur. J. Cell Biol., 32, 38
  15. 1985, J. Cell Biol., 101, 2253, 10.1083/jcb.101.6.2253 · DOI
  16. 1988, J. Cell Biol., 107, 2491, 10.1083/jcb.107.6.2491 · DOI
  17. 2003, Nat. Rev. Mol. Cell Biol., 4, 202, 10.1038/nrm1050 · DOI
  18. 1989, EMBO J., 8, 1041, 10.1002/j.1460-2075.1989.tb03471.x · DOI
  19. 1989, J. Cell Biol., 109, 2703, 10.1083/jcb.109.6.2703 · DOI
  20. 2000, Mol. Biol. Cell., 11, 4105, 10.1091/mbc.11.12.4105 · DOI · Paper page
  21. 2003, EMBO J., 22, 548, 10.1093/emboj/cdg062 · DOI
  22. 1998, Mol. Biol. Cell., 9, 809, 10.1091/mbc.9.4.809 · DOI
  23. 2000, J. Cell Biol., 149, 67, 10.1083/jcb.149.1.67 · DOI · Paper page
  24. 2001, Mol. Biol. Cell., 12, 3573, 10.1091/mbc.12.11.3573 · DOI
  25. 1985, J. Biol. Chem., 260, 12008, 10.1016/S0021-9258(17)38977-9 · DOI
  26. 1997, J. Biol. Chem., 272, 19884, 10.1074/jbc.272.32.19884 · DOI
  27. 1983, Cell., 35, 321, 10.1016/0092-8674(83)90235-0 · DOI
  28. 1997, Mol. Biol. Cell., 8, 1529, 10.1091/mbc.8.8.1529 · DOI
  29. 1992, J. Biol. Chem., 267, 11069, 10.1016/S0021-9258(19)49876-1 · DOI
  30. 1992, J. Cell Biol., 119, 249, 10.1083/jcb.119.2.249 · DOI
  31. 1993, J. Cell Biol., 121, 997, 10.1083/jcb.121.5.997 · DOI
  32. 1998, J. Cell Biol., 141, 359, 10.1083/jcb.141.2.359 · DOI
  33. 1989, Annu. Rev. Cell Biol., 5, 483, 10.1146/annurev.cb.05.110189.002411 · DOI
  34. 2000, J. Biol. Chem., 275, 25188, 10.1074/jbc.M001138200 · DOI
  35. 1996, Science., 272, 1008, 10.1126/science.272.5264.1008 · DOI · Paper page
  36. 2001, J. Cell Sci., 114, 1743, 10.1242/jcs.114.9.1743 · DOI · Paper page
  37. 2004, Mol. Biol. Cell., 15, 721, 10.1091/mbc.e03-07-0497 · DOI
  38. 1991, J. Cell Biol., 115, 1561, 10.1083/jcb.115.6.1561 · DOI
  39. 1999, J. Cell Biol., 146, 345, 10.1083/jcb.146.2.345 · DOI
  40. 1994, Cell., 77, 579, 10.1016/0092-8674(94)90219-4 · DOI · Paper page
  41. 1996, J. Biol. Chem., 271, 2171, 10.1074/jbc.271.4.2171 · DOI
  42. 2000, EMBO J., 19, 2193, 10.1093/emboj/19.10.2193 · DOI · Paper page
  43. 2001, J. Cell Sci., 114, 4469, 10.1242/jcs.114.24.4469 · DOI · Paper page
  44. 2004, EMBO J., 23, 386, 10.1038/sj.emboj.7600041 · DOI · Paper page
  45. 2001, Mol. Cell. Biol., 21, 7981, 10.1128/MCB.21.23.7981-7994.2001 · DOI
  46. 1999, Mol. Biol. Cell., 10, 875, 10.1091/mbc.10.4.875 · DOI
  47. 2000, J. Cell Biol., 151, 297, 10.1083/jcb.151.2.297 · DOI
  48. 2000, Proc. Natl. Acad. Sci. USA., 97, 9047, 10.1073/pnas.160251397 · DOI
  49. 2004, Science., 303, 495, 10.1126/science.1092586 · DOI · Paper page
  50. 1998, J. Cell Biol., 140, 1075, 10.1083/jcb.140.5.1075 · DOI
  51. 2001, Science., 292, 1712, 10.1126/science.1060750 · DOI · Paper page
  52. 2003, Mol. Biol. Cell., 14, 1545, 10.1091/mbc.02-07-0109 · DOI
  53. 2002, Nat. Cell Biol., 4, 394, 10.1038/ncb791 · DOI · Paper page
  54. 2003, Curr Opin. Cell Biol., 15, 446, 10.1016/S0955-0674(03)00080-2 · DOI
  55. 2001, Mol. Biol. Cell., 12, 3242, 10.1091/mbc.12.10.3242 · DOI
  56. 1992, J. Biol. Chem., 267, 15665, 10.1016/S0021-9258(19)49587-2 · DOI
  57. 1995, J. Cell Biol., 130, 1297, 10.1083/jcb.130.6.1297 · DOI
  58. 1991, J. Biol. Chem., 266, 22557, 10.1016/S0021-9258(18)54608-1 · DOI
  59. 2002, Mol. Biol. Cell., 13, 1313, 10.1091/mbc.01-10-0525 · DOI · Paper page
  60. 1981, Proc. Natl. Acad. Sci. USA., 78, 4289, 10.1073/pnas.78.7.4289 · DOI
  61. 2002, Mol. Biol. Cell., 13, 2826, 10.1091/mbc.02-05-0064 · DOI · Paper page
  62. 1997, J. Cell Biol., 137, 79, 10.1083/jcb.137.1.79 · DOI · Paper page
  63. 1998, J. Cell Biol., 142, 665, 10.1083/jcb.142.3.665 · DOI · Paper page
  64. 1992, EMBO J., 11, 2811, 10.1002/j.1460-2075.1992.tb05348.x · DOI · Paper page
  65. 1994, EMBO J., 13, 1287, 10.1002/j.1460-2075.1994.tb06381.x · DOI · Paper page
  66. 2001, J. Biol. Chem., 276, 28541, 10.1074/jbc.C100218200 · DOI
  67. 1998, J. Cell Sci., 111, 877, 10.1242/jcs.111.7.877 · DOI
  68. 2003, Mol. Biol. Cell., 14, 142, 10.1091/mbc.e02-06-0338 · DOI
  69. 1998, Cell., 94, 205, 10.1016/S0092-8674(00)81420-8 · DOI
  70. 2002, Mol. Biol. Cell., 13, 1965, 10.1091/mbc.e01-11-0131 · DOI
  71. 1999, Mol. Biol. Cell., 10, 3643, 10.1091/mbc.10.11.3643 · DOI
  72. 2001, Yeast., 18, 1, 10.1002/1097-0061(200101)18:1<1::AID-YEA644>3.0.CO;2-5 · DOI
  73. 2002, Proc. Natl. Acad. Sci. USA., 99, 6767, 10.1073/pnas.092142699 · DOI
  74. 2001, Science., 292, 1716, 10.1126/science.1060896 · DOI · Paper page

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Metadata

Authors
Arighi, C. N., Hartnell, L. M., Aguilar, R. C., Haft, C. R., & Bonifacino, J. S.
Venue
The Journal of Cell Biology
Publisher
Rockefeller University Press
Published
2004-04-12
Volume
165
Issue
1
Pages
123-133
ISSN
  • 1540-8140
  • 0021-9525
DOI
10.1083/jcb.200312055
PMC
PMC2172094
Cited by
580
References
2
Language
en

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