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The Pathological Effects of Circulating Hydrophobic Bile Acids in Alzheimer’s Disease

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Mapping pesticide-induced metabolic alterations in human gut bacteria

Chen, L., Yan, H., Di, S., Guo, C., Zhang, H., Zhang, S., Gold, A., Wang, Y., Hu, M., Wu, D., et al. (2025) · Nature Communications · doi:10.1038/s41467-025-59747-6 · Cited by 39

Obeticholic Acid Inhibits Anxiety via Alleviating Gut Microbiota-Mediated Microglia Accumulation in the Brain of High-Fat High-Sugar Diet Mice

Wu, L. M., Han, Y., Zheng, Z., Zhu, S., Chen, J., Yao, Y., Yue, S., Teufel, A., Weng, H., Li, L., et al. (2021) · Nutrients · doi:10.3390/nu13030940 · Cited by 36

Overview of oxidative stress findings in hepatic encephalopathy: From cellular and ammonium-based animal models to human data

Simičić, D., Cudalbu, C., & Pierzchała, K. (2022) · Analytical Biochemistry · doi:10.1016/j.ab.2022.114795 · Cited by 38

Gut–Brain Axis and Bile Acid Signaling: Linking Microbial Metabolism to Brain Function and Metabolic Regulation

Stanimirov, B., Đanić, M., Pavlović, N., Zaklan, D., Lazarević, S., Mikov, M., & Stankov, K. (2025) · International Journal of Molecular Sciences · doi:10.3390/ijms262412167 · Cited by 39

Distinct Bile Acid Signature in Parkinson's Disease With Mild Cognitive Impairment

Nie, K., Li, Y., Zhang, J., Gao, Y., Qiu, Y., Gan, R., Zhang, Y., & Wang, L. (2022) · Frontiers in Neurology · doi:10.3389/fneur.2022.897867 · Cited by 33

Linking Nonalcoholic Fatty Liver Disease and Brain Disease: Focusing on Bile Acid Signaling

Ren, Z., Li, C.-X., Ma, C., Chen, D., Chen, J., Xu, W., Chen, C.-A., Cheng, F., & Wang, X. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms232113045 · Cited by 32

Poria cocos could ameliorate cognitive dysfunction in APP / PS1 mice by restoring imbalance of Aβ production and clearance and gut microbiota dysbiosis

Sun, Y., Liu, Z., Pi, Z., Song, F., Wu, J., & Liu, S. (2021) · Phytotherapy Research · doi:10.1002/ptr.7014 · Cited by 32

Xanthohumol ameliorates Diet-Induced Liver Dysfunction via Farnesoid X Receptor-Dependent and Independent Signaling

Paraiso, I. L., Tran, T. Q., Magaña, A. A., Kundu, P., Choi, J., Maier, C. S., Bobe, G., Raber, J., Kioussi, C., & Stevens, J. F. (2021) · Frontiers in Pharmacology · doi:10.3389/fphar.2021.643857 · Cited by 31

Liver’s influence on the brain through the action of bile acids

Yeo, X. Y., Tan, L. Y., Chae, W. R., Lee, D., Lee, Y., Wüestefeld, T., & Jung, S. (2023) · Frontiers in Neuroscience · doi:10.3389/fnins.2023.1123967 · Cited by 35

Bile acids, bioactive signalling molecules in interoceptive gut‐to‐brain communication

Joyce, S. A., & O'Malley, D. (2022) · The Journal of Physiology · doi:10.1113/jp281727 · Cited by 32

A critical review of bile acids and their receptors in hepatic encephalopathy

Williams, E., Chu, C. S., & DeMorrow, S. (2021) · Analytical Biochemistry · doi:10.1016/j.ab.2021.114436 · Cited by 34

Mechanistic insights into the liver–brain axis during chronic liver disease

Siddle, M. R., Durán, R. G., Goel, D., Renquist, B. J., Holt, M. K., & Hadjihambi, A. (2025) · Nature Reviews Gastroenterology & Hepatology · doi:10.1038/s41575-025-01142-z · Cited by 36

Type I IFNs link skin-associated dysbiotic commensal bacteria to pathogenic inflammation and angiogenesis in rosacea

Mylonas, A., Hawerkamp, H. C., Wang, Y., Chen, J., Messina, F., Demaria, O., Meller, S., Homey, B., Domizio, J. D., Mazzolai, L., et al. (2023) · JCI Insight · doi:10.1172/jci.insight.151846 · Cited by 30

Depression-associated gut microbes, metabolites and clinical trials

Wang, M., Song, Z., Lai, S., Tang, F., Dou, L., & Yang, F. (2024) · Frontiers in Microbiology · doi:10.3389/fmicb.2024.1292004 · Cited by 32

Bile acid metabolites predict multiple sclerosis progression and supplementation is safe in progressive disease

Ladakis, D. C., Harrison, K. L., Smith, M. D., Solem, K., Gadani, S. P., Jank, L., Hwang, S. A., Farhadi, F., Dewey, B. E., Fitzgerald, K. C., et al. (2024) · Med · doi:10.1016/j.medj.2024.09.011 · Cited by 30

Unconjugated bilirubin elevation impairs the function and expression of breast cancer resistance protein (BCRP) at the blood-brain barrier in bile duct-ligated rats

Xu, P., Ling, Z., Zhang, J., Li, Y., Shu, N., Zhong, Z., Chen, Y., Di, X., Wang, Z., Liu, L., et al. (2016) · Acta Pharmacologica Sinica · doi:10.1038/aps.2016.25 · Cited by 29

Increased serum bile acids after extrahepatic biliary obstruction causes leakiness to the blood brain barrier via the disruption of tight junctions

DeMorrow, S., Frampton, G. A., Galindo, C., Pae, H. Y., & Quinn, M. A. (2012) · The FASEB Journal · doi:10.1096/fasebj.26.1_supplement.1110.7 · Cited by 3

Blood-brain barrier permeability is markedly decreased in cholestasis in the rat

Wahler, J. B., Swain, M. G., Carson, R. E., Bergasa, N. V., & Jones, E. A. (1993) · Hepatology · doi:10.1002/hep.1840170625 · Cited by 18

Increased Serum Bile Acids After Extraheptic Biliary Obstruction Causes Leakiness to the Blood Brain Barrier via the Disruption of Tight Junctions

Quinn, M. A., Frampton, G. A., Pae, H. Y., Horvat, D., Huang, L., & DeMorrow, S. (2011) · Gastroenterology · doi:10.1016/s0016-5085(11)63890-0 · Cited by 1

The Effect of Bile Salts on the Permeability and Ultrastructure of the Perfused, Energy-Depleted, Rat Blood-Brain Barrier

Greenwood, J., Adu, J., DAVEY, A. J., Abbott, N. J., & Bradbury, M. W. B. (1991) · Journal of Cerebral Blood Flow & Metabolism · doi:10.1038/jcbfm.1991.116 · Cited by 71

Bile duct ligation-induced cirrhosis does not alter the blood-brain barrier permeability to sucrose in rats

Miah, M. K., Bickel, U., & Mehvar, R. (2024) · Metabolic Brain Disease · doi:10.1007/s11011-024-01486-6 · Cited by 3