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Abuse of prescription drugs and the risk of addiction

Compton, Wilson M., Volkow, Nora D.·2006·Drug and Alcohol Dependence
DOI 10.1016/j.drugalcdep.2005.10.020
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Abstract

Abuse of several categories of prescription drugs has increased markedly in the United States in the past decade and is now at alarming levels for certain agents, especially opioid analgesics and stimulants. Prescription drugs of abuse fit into the same pharmacological classes as their non-prescription counterparts. Thus, the potential factors associated with abuse or addiction versus safe therapeutic use of these agents relates to the expected variables: dose, route of administration, co-administration with other drugs, context of use, and expectations. Future scientific work on prescription drug abuse will include identification of clinical practices that minimize the risks of addiction, the development of guidelines for early detection and management of addiction, and the development of clinically effective agents that minimize the risks for abuse. With the high rates of prescription drug abuse among teenagers in the United States, a particularly urgent priority is the investigation of best practices for effective prevention and treatment for adolescents, as well as the development of strategies to reduce diversion and abuse of medications intended for medical use.

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Research works printed but not linked: 23

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Metadata

Authors
Compton, W. M., & Volkow, N. D.
Venue
Drug and Alcohol Dependence
Publisher
Elsevier BV
Published
2006-06
Volume
83
Pages
S4-S7
ISSN
0376-8716
DOI
10.1016/j.drugalcdep.2005.10.020
Cited by
363
References
0
Language
en
Licence
www.elsevier.com/tdm/userlicense/1.0/ (tdm)

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