Cited by 53Reproductive Biology and FertilityOvarian function and disordersGenetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities

Outcome of ovarian stimulation for oocyte cryopreservation in women with Turner syndrome

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Talaulikar, Vikram Sinai, Conway, Gerard S., Pimblett, Antoinette, Davies, Melanie C.·2019·Fertility and Sterility

Abstract

Objective To study the safety and efficacy of ovarian stimulation and oocyte cryopreservation as a method of fertility preservation in women with Turner syndrome (TS).Design Retrospective cohort study.Setting Reproductive medicine clinic.Patient(s) Seven women with TS who attended the clinic between 2011 and 2017.Intervention(s) Ovarian stimulation and oocyte cryopreservation.Main outcomes measure(s) Number of oocytes cryopreserved, ovarian hyperstimulation syndrome.Result(s) The oocyte retrieval rates (mean ± SD, 9 ± 3.16) in women with TS were comparable to the published data from healthy women. The oocyte yield was higher than expected based on the low antimüllerian hormone levels. There was no correlation between baseline antimüllerian hormone or antral follicle count levels and the number of oocytes retrieved.Conclusion(s) Oocyte cryopreservation after ovarian stimulation appears to be safe and successful in women with mosaic TS who wish to consider fertility preservation.

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Crossref · 10.1016/j.fertnstert.2018.11.010

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  • Published data regarding oocyte cryopreservation in individuals with TS entails six retrospective studies and eight case reports comprising a total of 80 individuals ranging in age from 7 to 30 years.

    “To date, published data regarding oocyte cryopreservation in individuals with TS entails six retrospective studies and eight case reports comprising a total of 80 individuals ranging in age from 7 to 30 years.578,591,596-607”

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  1. Hewitt JK, Jayasinghe Y, Amor DJ, Gillam LH, Warne GL, Grover S, et al. Fertility in Turner syndrome. Clin Endocrinol 2013;79:606-14.

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Authors
Talaulikar, V. S., Conway, G. S., Pimblett, A., & Davies, M. C.
Affiliations
University College Hospital (GB)
Corresponding author
Talaulikar, Vikram Sinai
Venue
Fertility and Sterility
Publisher
Elsevier BV
Published
2019-03
Volume
111
Issue
3
Pages
505-509
ISSN
0015-0282 (ISSN-L)
OpenAlex
W2907720263
Cited by
53
References
34
Citations by year
2026: 2 · 2025: 3 · 2024: 3 · 2023: 8 · 2022: 12 · 2021: 9 · 2020: 10 · 2019: 6
FWCI
5.95
Type
journal article
Language
en
Open access
Locations
  • Fertility and Sterility (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Reproductive Biology and Fertility
  • Health Sciences › Medicine › Reproductive Medicine › Ovarian function and disorders
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
Keywords
Turner syndrome, ovulation induction, oocyte cryopreservation, fertility preservation, ovarian hyperstimulation syndrome, oocyte retrieval, oocyte yield, anti-Müllerian hormone, antral follicle count, mosaic Turner syndrome
MeSH terms
Adolescent, Adult, Female, Fertility Agents, Female, Humans, Infertility, Female, Oocytes, Ovulation, Ovulation Induction, Pregnancy, Retrospective Studies, Turner Syndrome, Cryopreservation, Ovarian Hyperstimulation Syndrome, Treatment Outcome, Oocyte Retrieval, Young Adult, Fertility Preservation, Ovarian Reserve

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