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Microwave-assisted hydrothermal extraction of sulfated polysaccharides from Ulva spp. and Monostroma latissimum
Abstract
Microwave-assisted hydrothermal extraction was applied for production of sulfated polysaccharides from Ulva spp. and Monostroma latissimum. The maximum ulvan yields attained 40.4±3.2% (Ulva meridionalis) and 36.5±3.1% (Ulva ohnoi) within 4min of come-up time and 10min of extraction time at 160°C, respectively. The rhamnan sulfate yield from M. latissimum further attained 53.1±7.2% at 140°C. The sulfated polysaccharides were easily recovered from the extract by simple ethanol precipitation. In addition, molecular weights and viscosity of the extracted polysaccharides could be controlled by varying the extraction temperature. Dielectric measurement revealed that ionic conduction was the important parameter that affect the microwave susceptibility of algae-water mixture. The sulfated polysaccharides extracts are expected as potential feedstock for medical and food applications.
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“Both of the compounds exhibit biological activities, such as antitumor, anticoagulant, antiviral, and antiherpetic [83].”
From Overview on the Application of Modern Methods for the Extraction of Bioactive Compounds from Marine Macroalgae (2018) · cites this paper as [83]
Citations
Cites
Recent advances in extraction of nutraceuticals from plants
Wang, L., & Weller, C. L. (2006) · Trends in Food Science & Technology · doi:10.1016/j.tifs.2005.12.004 · Cited by 2,046
Roles of Water for Chemical Reactions in High-Temperature Water
Akiya, N., & Savage, P. E. (2002) · Chemical Reviews · doi:10.1021/cr000668w · Cited by 1,581
Dielectric parameters relevant to microwave dielectric heating
Gabriel, C., Gabriel, S., Grant, E. H., Grant, E. H., Halstead, B. S. J., & Mingos, D. M. P. (1998) · Chemical Society Reviews · doi:10.1039/a827213z · Cited by 1,406
Fucoidan: Structure and bioactivity
Li, B., Lu, F., Wei, X., & Zhao, R. (2008) · Molecules · doi:10.3390/molecules13081671 · Cited by 1,383
Structure and Functional Properties of Ulvan, a Polysaccharide from Green Seaweeds
Lahaye, M., & Robic, A. (2007) · Biomacromolecules · doi:10.1021/bm061185q · Cited by 1,024
Berteau, O. (2003) · Glycobiology · doi:10.1093/glycob/cwg058 · Cited by 769
Microwave-assisted extractions of active ingredients from plants
Chan, C.-H., Yusoff, R., Ngoh, G.-C., & Kung, F. W.-L. (2011) · Journal of Chromatography A · doi:10.1016/j.chroma.2011.07.040 · Cited by 687
Bioactivity and applications of sulphated polysaccharides from marine microalgae
Raposo, M., De Morais, R., & Bernardo de Morais, A. (2013) · Marine Drugs · doi:10.3390/md11010233 · Cited by 594
Marine Polysaccharides in Pharmaceutical Applications: An Overview
Laurienzo, P. (2010) · Marine Drugs · doi:10.3390/md8092435 · Cited by 538
World’s largest macroalgal bloom caused by expansion of seaweed aquaculture in China
Liu, D., Keesing, J. K., Xing, Q., & Shi, P. (2009) · Marine Pollution Bulletin · doi:10.1016/j.marpolbul.2009.01.013 · Cited by 532
Microwave-assisted extraction of sulfated polysaccharides (fucoidan) from brown seaweed
Rodriguez-Jasso, R. M., Mussatto, S. I., Pastrana, L., Aguilar, C. N., & Teixeira, J. A. (2011) · Carbohydrate Polymers · doi:10.1016/j.carbpol.2011.06.006 · Cited by 434
Wang, L., Wang, X., Wu, H., & Liu, R. (2014) · Marine Drugs · doi:10.3390/md12094984 · Cited by 269
Hydrothermal processing of algal biomass for the production of biofuels and chemicals
Biller, P., & Ross, A. B. (2012) · Biofuels · doi:10.4155/bfs.12.42 · Cited by 145
Dielectric relaxation of water and heavy water in the whole fluid phase
Okada, K., Yao, M., Hiejima, Y., Kohno, H., & Kajihara, Y. (1999) · The Journal of Chemical Physics · doi:10.1063/1.477897 · Cited by 128
Hiraoka, M., Shimada, S., Uenosono, M., & Masuda, M. (2004) · Phycological Research · doi:10.1111/j.1440-1835.2003.00321.x · Cited by 120
Self-citationYoshida, T., Tsubaki, S., Teramoto, Y., & Azuma, J. (2010) · Bioresource Technology · doi:10.1016/j.biortech.2010.05.011 · Cited by 118
Self-citationQuitain, A. T., Kai, T., Sasaki, M., & Goto, M. (2013) · Industrial & Engineering Chemistry Research · doi:10.1021/ie400527b · Cited by 97
Antiviral Activities against HSV-1, HCMV, and HIV-1 of Rhamnan Sulfate fromMonostroma latissimum
Lee, J., Hayashi, K., Hayashi, T., Sankawa, U., & Maeda, M. (1999) · Planta Medica · doi:10.1055/s-2006-960804 · Cited by 96
Structure of rhamnan sulfate from the green alga Monostroma nitidum and its anti-herpetic effect
Lee, J., Koizumi, S., Hayashi, K., & Hayashi, T. (2010) · Carbohydrate Polymers · doi:10.1016/j.carbpol.2010.03.014 · Cited by 96
Li, H., Mao, W., Zhang, X., Qi, X., Chen, Y., Chen, Y., Xu, J. F., Zhao, C., Hou, Y., Yang, Y., et al. (2011) · Carbohydrate Polymers · doi:10.1016/j.carbpol.2011.02.042 · Cited by 89
Microwave Heating of Tea Residue Yields Polysaccharides, Polyphenols, and Plant Biopolyester
Tsubaki, S., Iida, H., Sakamoto, M., & Azuma, J. (2008) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf802253s · Cited by 85
Self-citationMaeda, M., Uehara, T., Harada, N., Sekiguchi, M., & Hiraoka, A. (1991) · Phytochemistry · doi:10.1016/0031-9422(91)80076-d · Cited by 84
Hiraoka, M., Shimada, S., Uenosono, M., et al. (2004) · Phycological Research · doi:10.1111/j.1440-1835.2004.tb00311.x · Cited by 82
Self-citationChemical Structure of Antithrombin-active Rhamnan Sulfate fromMonostrom nitidum
HARADA, N., & Maeda, M. (1998) · Bioscience Biotechnology and Biochemistry · doi:10.1271/bbb.62.1647 · Cited by 74
Uy, S. F., Easteal, A. J., Farid, M. M., Keam, R. B., & Conner, G. T. (2005) · Carbohydrate Research · doi:10.1016/j.carres.2005.02.008 · Cited by 62
Microwave-assisted hydrothermal hydrolysis of cellobiose and effects of additions of halide salts
Tsubaki, S., Oono, K., Onda, A., Yanagisawa, K., & Azuma, J. (2012) · Bioresource Technology · doi:10.1016/j.biortech.2012.07.086 · Cited by 54
Self-citationTsubaki, S., Ozaki, Y., & Azuma, J.-I. (2010) · Journal of Food Science · doi:10.1111/j.1750-3841.2009.01466.x · Cited by 49
Self-citationHydrolysis of green-tide forming Ulva spp. by microwave irradiation with polyoxometalate clusters
Tsubaki, S., Oono, K., Hiraoka, M., Ueda, T., Onda, A., Yanagisawa, K., & Azuma, J. (2013) · Green Chemistry · doi:10.1039/c3gc42027b · Cited by 46
Self-citationApplication of Microwave Technology for Utilization of Recalcitrant Biomass
Tsubaki, S., & Azum, J.-I. (2011) · InTech eBooks · doi:10.5772/14040 · Cited by 44
Self-citationRhamnan sulfate from cell walls of monostroma latissimum
Lee, J., Yamagaki, T., Maeda, M., & Nakanishi, H. (1998) · Phytochemistry · doi:10.1016/s0031-9422(97)00927-8 · Cited by 42
Tsubaki, S., Hiraoka, M., Hadano, S., Nishimura, H., Kashimura, K., & Mitani, T. (2014) · Carbohydrate Polymers · doi:10.1016/j.carbpol.2014.03.002 · Cited by 27
Self-citationTsubaki, S., Hiraoka, M., Hadano, S., Okamura, K., Ueda, T., Nishimura, H., Kashimura, K., & Mitani, T. (2014) · Carbohydrate Polymers · doi:10.1016/j.carbpol.2014.08.092 · Cited by 19
Self-citationHiraoka, M. (2012) · Journal of the Japan Institute of Energy · Cited by 10
Self-citationStudy on Algal Culture System Using the Ulva Meridionalis
MIZUNO, Y., Kishimoto, A., Noguchi, T., Yukumoto, M., & Hiraoka, M. (2013) · Journal of the Japan Institute of Energy · doi:10.3775/jie.92.1191 · Cited by 1
Self-citation
Research works printed but not linked: 2
- Hiraoka, 2012, Intensive biomass production by green seaweed Ulva, Journal of the Japan Institute of Energy, 91, 1154
- Horimoto, 2011, Enteromorpha-like Ulva (Ulvophyceae, Chlorophyta) growing in the Todoroki river, Ishigaki Island, Japan, with special reference to Ulva meridionalis Horimoto et Shimada, sp. nov, Bulletin of the National Museum of Nature and Science Series B, 37, 155
Cited by
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Barkia, I., Saari, N., & Manning, S. R. (2019) · Marine Drugs · doi:10.3390/md17050304 · Cited by 719
Ulvan: A systematic review of extraction, composition and function
Kidgell, J. T., Magnusson, M. E., de Nys, R., & Glasson, C. R. K. (2019) · Algal Research · doi:10.1016/j.algal.2019.101422 · Cited by 714
Zhang, B., Biswal, B. K., Zhang, J., & Balasubramanian, R. (2023) · Chemical Reviews · doi:10.1021/acs.chemrev.2c00673 · Cited by 441
Recent Advances in Marine Algae Polysaccharides: Isolation, Structure, and Activities
Xu, S., Huang, X., & Cheong, K. (2017) · Marine Drugs · doi:10.3390/md15120388 · Cited by 424
Ji, X., Peng, Q., Yuan, Y., Shen, J., Xie, X., & Wang, M. (2017) · Food Chemistry · doi:10.1016/j.foodchem.2017.01.074 · Cited by 323
Metadata
- Authors
- Tsubaki, S., Oono, K., Hiraoka, M., Onda, A., & Mitani, T.
- Affiliations
- University of Kochi (JP)
- Kyoto University (JP)
- Corresponding author
- Tsubaki, Shuntaro
- Venue
- Food Chemistry
- Publisher
- Elsevier BV
- Published
- 2016-11
- Volume
- 210
- Pages
- 311-316
- ISSN
- 0308-8146 (ISSN-L)
- OpenAlex
- W2344766551
- Cited by
- 150
- References
- 33
- Citations by year
- 2026: 15 · 2025: 12 · 2024: 20 · 2023: 13 · 2022: 20 · 2021: 14 · 2020: 17 · 2019: 14 · 2018: 10 · 2017: 14 · 2016: 1
- FWCI
- 18.71
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Food Chemistry (publishedVersion)
- PubMed (publishedVersion)
- Funders
- Ministry of Education, Culture, Sports, Science and Technology of Japan
- Topics
- Life Sciences › Agricultural and Biological Sciences › Aquatic Science › Seaweed-derived Bioactive Compounds
- Life Sciences › Agricultural and Biological Sciences › Food Science › Polysaccharides Composition and Applications
- Life Sciences › Agricultural and Biological Sciences › Plant Science › Polysaccharides and Plant Cell Walls
- Keywords
- sulfated polysaccharides, ulvan, Ulva ohnoi, brown algae, extraction temperature, molecular weight control, viscosity, dielectric properties, ionic conduction, ethanol precipitation
- MeSH terms
- Chlorophyta, Deoxy Sugars, Mannans, Microwaves, Polysaccharides, Viscosity, Ulva
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