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Omega-3 Fatty Acids Prevent Inflammation and Metabolic Disorder through Inhibition of NLRP3 Inflammasome Activation
Open accessAbstract
Omega-3 fatty acids (ω-3 FAs) have potential anti-inflammatory activity in a variety of inflammatory human diseases, but the mechanisms remain poorly understood. Here we show that stimulation of macrophages with ω-3 FAs, including eicosapentaenoic acid (EPA), docosahexaenoic acid (DHA), and other family members, abolished NLRP3 inflammasome activation and inhibited subsequent caspase-1 activation and IL-1β secretion. In addition, G protein-coupled receptor 120 (GPR120) and GPR40 and their downstream scaffold protein β-arrestin-2 were shown to be involved in inflammasome inhibition induced by ω-3 FAs. Importantly, ω-3 FAs also prevented NLRP3 inflammasome-dependent inflammation and metabolic disorder in a high-fat-diet-induced type 2 diabetes model. Our results reveal a mechanism through which ω-3 FAs repress inflammation and prevent inflammation-driven diseases and suggest the potential clinical use of ω-3 FAs in gout, autoinflammatory syndromes, or other NLRP3 inflammasome-driven inflammatory diseases.
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“The anti-inflammatory effects of omega-3 fatty acids seems to be mediated by binding to the G-protein–coupled receptor 120 and inhibition of NLRP3 inflammasome activity (53,54).”
From Health Benefits of the Mediterranean Diet: Metabolic and Molecular Mechanisms (2018) · cites this paper as [54]
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Cites
A role for mitochondria in nlrp3 inflammasome activation
Zhou, R., Yazdi, A. S., Menu, P., & Tschopp, J. (2011) · Nature · doi:10.1038/nature09663 · Cited by 5,602
Self-citationGout-associated uric acid crystals activate the NALP3 inflammasome
Martinon, F., Pétrilli, V., Mayor, A., Tardivel, A., & Tschopp, J. (2006) · Nature · doi:10.1038/nature04516 · Cited by 5,326
Self-citationType 2 diabetes as an inflammatory disease
Donath, M. Y., & Shoelson, S. E. (2011) · Nature Reviews Immunology · doi:10.1038/nri2925 · Cited by 3,737
Thioredoxin-interacting protein links oxidative stress to inflammasome activation
Zhou, R., Tardivel, A., Thorens, B., Choi, I., & Tschopp, J. (2010) · Nature Immunology · doi:10.1038/ni.1831 · Cited by 2,708
Self-citationThe NLRP3 inflammasome instigates obesity-induced inflammation and insulin resistance
Vandanmagsar, B., Youm, Y.-H., Ravussin, A., Galgani, J. E., Stadler, K., Mynatt, R. L., Ravussin, E., Stephens, J. M., & Dixit, V. D. (2011) · Nature Medicine · doi:10.1038/nm.2279 · Cited by 2,655
The Inflammasomes: Guardians of the Body
Martinon, F., Mayor, A., & Tschopp, J. (2009) · Annual Review of Immunology · doi:10.1146/annurev.immunol.021908.132715 · Cited by 2,436
Self-citationOh, D. Y., Talukdar, S., Bae, E. J., Imamura, T., Morinaga, H., Fan, W., Li, P., Lu, W. J., Watkins, S. M., & Olefsky, J. M. (2010) · Cell · doi:10.1016/j.cell.2010.07.041 · Cited by 2,428
Inflammasomes in health and disease
Strowig, T., Henao-Mejia, J., Elinav, E., & Flavell, R. (2012) · Nature · doi:10.1038/nature10759 · Cited by 2,230
Endres, S., Ghorbani, R., Kelley, V. E., Georgilis, K., Lonnemann, G., van der Meer, J. W. M., Cannon, J. G., Rogers, T. S., Klempner, M. S., Weber, P. C., et al. (1989) · New England Journal of Medicine · doi:10.1056/nejm198902023200501 · Cited by 1,911
Fatty acid–induced NLRP3-ASC inflammasome activation interferes with insulin signaling
Wen, H., Gris, D., Lei, Y., Jha, S., Zhang, L., Huang, M. T.-H., Brickey, W. J., & Ting, J. P.-Y. (2011) · Nature Immunology · doi:10.1038/ni.2022 · Cited by 1,698
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Morini, M. A., & Pedroni, V. I. (2025) · Biophysica · doi:10.3390/biophysica5040044 · Cited by 7
Krajewski, P. K., Tsoukas, M. M., & Szepietowski, J. C. (2024) · Current Issues in Molecular Biology · doi:10.3390/cimb46010043 · Cited by 4
Heine, L. K., Scarlett, T., Wagner, J. G., Lewandowski, R. P., Benninghoff, A. D., Tindle, A. N., Skedel, A. E., Harkema, J. R., & Pestka, J. J. (2024) · Inhalation Toxicology · doi:10.1080/08958378.2024.2318378 · Cited by 4
Lee, J.-E., Lee, J., Koh, J., & Im, D. (2024) · International Journal of Molecular Sciences · doi:10.3390/ijms25115866 · Cited by 5
Omega-3 and omega-6 fatty acids: Inverse association with body fat percentage and obesity risk
Yang, Z. Y., Lan, Y., Yang, K., Zhang, J., Chen, L., Meng, T., Wu, M., & Lu, X. (2025) · Nutrition Research · doi:10.1016/j.nutres.2025.01.001 · Cited by 4
Wang, T., Chen, S., Zhou, D., & Hong, Z. (2025) · Metabolism · doi:10.1016/j.metabol.2025.156148 · Cited by 7
Eicosapentaenoic acid modulates fatty acid metabolism and inflammation in Psammomys obesus
Atek-Mebarki, F., Hichami, A., Abdoul‐Azize, S., Bitam, A., Koceir, E.-A., & Khan, N. A. (2014) · Biochimie · doi:10.1016/j.biochi.2014.12.004 · Cited by 4
Are marine n-3 fatty acids protective towards insulin resistance? From cell to human
Delarue, J. (2020) · Proceedings of The Nutrition Society · doi:10.1017/s0029665120000087 · Cited by 4
Aye, I. L. M. H., Lager, S., & Powell, T. L. (2015) · Springer eBooks · doi:10.1007/978-3-319-16853-1_6 · Cited by 5
Vahedi, L., Ostadrahimi, A., Edalati-Fard, F., Aslani, H., & Farshbaf‐Khalili, A. (2018) · Journal of Complementary and Integrative Medicine · doi:10.1515/jcim-2018-0010 · Cited by 5
How the Dietary Saturated/Monounsaturated Fatty Acid Ratio Modulates Brain Function in Older Adults
Kien, C. L., & Dumas, J. A. (2025) · Nutrients · doi:10.3390/nu17111897 · Cited by 3
Gao, A., Guo, T., Yang, Z., Qiu, H., & Gao, R. (2025) · Reviews in Cardiovascular Medicine · doi:10.31083/rcm36438 · Cited by 3
Progress on Omega-3 fatty acids for the comprehensive and targeted treatment of spinal cord injury
Yuan, Z., Shi, L., Tao, X.-N., Fan, X., Zheng, H., Shang, Y., Zhao, X., Yang, F., Lin, H. X., Xiao, P., et al. (2026) · Bone Research · doi:10.1038/s41413-025-00461-w · Cited by 4
Rao, P. P. (2026) · Obesity Medicine · doi:10.1016/j.obmed.2026.100694 · Cited by 3
Zhang, H., Zhu, M., Qu, Y., Zhang, X., Wu, Z., & Wang, Z. (2026) · Frontiers in Nutrition · doi:10.3389/fnut.2026.1789924 · Cited by 4
Metabolite sensing receptors in macrophage reprogramming: from inflammation to resolution
Rai, S. K., Gupta, S., & Sarangi, P. P. (2026) · Inflammation Research · doi:10.1007/s00011-026-02240-7 · Cited by 3
Mafra, D., Alvarenga, L., de Velasco, P. C., Manhães, L. D. M., Santana, L. D. D. S. E., & Borges, N. A. (2025) · Molecular and Cellular Biochemistry · doi:10.1007/s11010-025-05359-z · Cited by 4
Yogic diet on gut microbial diversity in asthma
Das, M., Pundir, M., Nayak, P., Patra, S., & Thajuddin, N. (2023) · Yoga Mimamsa · doi:10.4103/ym.ym_7_23 · Cited by 3
Rojas-Solé, C., Torres-Herrera, B., Gelerstein-Claro, S., Medina-Pérez, D., Gómez-Venegas, H., Alzolay-Sepúlveda, J., Chichiarelli, S., Saso, L., & Rodrigo, R. (2024) · Applied Sciences · doi:10.3390/app14114548 · Cited by 3
Li, A., Wang, X., Li, J., Li, X., Wang, J., Liu, Y., Wang, Z., Yang, X., Gao, J., Wu, J., et al. (2024) · Cell Reports · doi:10.1016/j.celrep.2024.114858 · Cited by 3
NLRP3 inflammasome: A novel target for T2DM treatment?
Jiang, H., & Zhou, R. (2016) · Chinese Science Bulletin (Chinese Version) · doi:10.1360/n972016-00653 · Cited by 3
Self-citationFaraj, M. (2019) · Médecine des Maladies Métaboliques · doi:10.1016/s1957-2557(19)30042-2 · Cited by 3
Nutritional factors in the prevention and treatment of gout
Tomaszuk, S., Wąsik, K., & Wojtuś, M. (2023) · Quality in Sport · doi:10.12775/qs.2023.09.02.004 · Cited by 2
Valiauga, R., Talley, S., Khemmani, M., Noronha, M. F., Gogliotti, R. G., Wolfe, A. J., & Campbell, E. M. (2024) · Journal of Neuroinflammation · doi:10.1186/s12974-024-03140-5 · Cited by 2
Song, C., Li, S., Yuan, Y., Gao, W., Qiu, X., Tan, L., Sun, Y., Tang, N., Qu, Y., Liao, Y., et al. (2025) · Veterinary Microbiology · doi:10.1016/j.vetmic.2025.110635 · Cited by 2
Cho, H., Kim, J., Park, Y., Kim, Y., & Chung, S. (2025) · Nutrients · doi:10.3390/nu17193063 · Cited by 2
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何曉碩, 郭战利, & Chen, Q. (2026) · Reviews in Endocrine and Metabolic Disorders · doi:10.1007/s11154-026-10067-0 · Cited by 3
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Zhang, Y., Zhang, X., Zhu, P., Tan, R.-H., Zhao, J., Wang, F., Zhang, J., Yan, W., Yang, X., Wan, J., et al. (2018) · Journal of Functional Foods · doi:10.1016/j.jff.2018.04.010 · Cited by 2
Chen, L., Xie, L., Zhang, J., Feng, Y., & Wu, X. (2023) · PLoS ONE · doi:10.1371/journal.pone.0290051 · Cited by 2
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Młynarska, E., Sinkowska, J., Kurciński, S., Marcinkowska, W., Leszto, K., Jakubowska, P., Rysz, J., & Franczyk, B. (2025) · Nutrients · doi:10.3390/nu17223617 · Cited by 3
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Wang, Y., Liu, J., Liu, H., Lingzhi, L., Gao, X., Tong, Y., Song, S., & Yan, C. (2022) · Journal of Agricultural and Food Chemistry · doi:10.1021/acs.jafc.2c00099 · Cited by 2
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Leleu, D., Farnier, M., Chague, F., Palleschi, D., Machado, M., Gougeon, M., de Barros, J.-P. P., Nguyen, M., Bichât, F., Maza, M., et al. (2025) · European Journal of Preventive Cardiology · doi:10.1093/eurjpc/zwaf673 · Cited by 1
Shen, S., Chang, Q., Zhao, Y., Yin, X., Cao, Z. W., Xue, H., Zeng, Q., Wang, X., & Wang, P. (2025) · The Journal of Nutritional Biochemistry · doi:10.1016/j.jnutbio.2025.110186 · Cited by 1
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Shen, M., Wang, Z., Jing, D., Yang, S., Xiao, Y., & Chen, X. (2025) · JID Innovations · doi:10.1016/j.xjidi.2025.100437 · Cited by 1
Cui, X.-H., Yu, L., Yang, M., Liu, W., Huang, Y., Zhao, J., Fang, Z.-M., Wang, X., Jiang, D.-S., & Yi, X. (2026) · Respiratory Research · doi:10.1186/s12931-026-03499-4 · Cited by 1
Li, C., Fan, J., Sun, T., Cui, W., Zou, J., Yang, W., Chen, L., Xiao, J., Wang, S., Zhang, T., et al. (2026) · Advanced Science · doi:10.1002/advs.202512133 · Cited by 1
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Gao, S., Yin, N., Wei, R., Li, X., Cheng, Q., Zhula, A., Zhou, W., Zhang, Y., Li, S., Wei, Z., et al. (2026) · Nature Communications · doi:10.1038/s41467-026-74917-w · Cited by 2
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Buckner, T. (2016) · Lincoln (University of Nebraska) · Cited by 1
Bareksei, A., Hafner, G., Pfeiffer, S., & Schlatterer, K. (2019) · International Journal of Clinical and Experimental Medical Sciences · doi:10.11648/j.ijcems.20190505.11 · Cited by 1
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Costantino, E., & Actis, A. B. (2018) · Nutrition and Cancer · doi:10.1080/01635581.2018.1521439 · Cited by 1
Farry, F., Ismiarto, Y. D., Chaidir, M. R., & Ismono, D. (2020) · Majalah kedokteran Bandung/Majalah Kedokteran Bandung · doi:10.15395/mkb.v52n2.1784 · Cited by 1
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Perera, A. P. (2019) · UTAS Research Repository · doi:10.25959/100.00034330 · Cited by 1
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Wang, Y., & Leung, P. S. (2017) · Springer eBooks · doi:10.1007/978-3-319-67199-4_101625 · Cited by 1
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Thomas, J., & Garg, M. L. (2016) · Elsevier eBooks · doi:10.1016/b978-0-12-801585-8.00023-3
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Metadata
- Authors
- Yan, Y., Jiang, W., Spinetti, T., Tardivel, A., Castillo, R., Bourquin, C., Guarda, G., Tian, Z., Tschopp, J., & Zhou, R.
- Affiliations
- University of Science and Technology of China (CN)
- University of Fribourg (CH)
- University of Lausanne (CH)
- Corresponding author
- Tian, Zhigang
- Zhou, Rongbin
- ORCID
- Venue
- Immunity
- Publisher
- Elsevier BV
- Published
- 2013-06
- Volume
- 38
- Issue
- 6
- Pages
- 1154-1163
- ISSN
- 1074-7613 (ISSN-L)
- OpenAlex
- W1998522372
- Cited by
- 784
- References
- 48
- Citations by year
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- FWCI
- 24.95
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Licence
- www.elsevier.com/tdm/userlicense/1.0/ (tdm)
- www.elsevier.com/legal/tdmrep-license (tdm)
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- doi.org/10.15223/policy-037 (stm-asf)
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- doi.org/10.15223/policy-029 (stm-asf)
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- Immunity (publishedVersion)
- PubMed (publishedVersion)
- IRIS (submittedVersion)
- SERVAL (Université de Lausanne) (submittedVersion)
- Open Access CRIS of the University of Bern
- Funders
- National Natural Science Foundation of China (81222040, 31200659, 81273318, 91029303)
- Ministry of Education of the People's Republic of China (20123402110010, 20123402120001)
- University of Science and Technology of China
- Chinese Academy of Sciences
- Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung
- Louis-Jeantet Foundation
- Fundamental Research Funds for the Central Universities
- Program for New Century Excellent Talents in University
- Seventh Framework Programme
- National Key Research and Development Program of China (2013CB944904)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Inflammasome and immune disorders
- Health Sciences › Nursing › Nutrition and Dietetics › Fatty Acid Research and Health
- Life Sciences › Immunology and Microbiology › Immunology › Immune Response and Inflammation
- Keywords
- omega-3 fatty acids, NLRP3 inflammasome, caspase-1 activation, IL-1β secretion, macrophages, GPR120, GPR40, β-arrestin2, eicosapentaenoic acid, docosahexaenoic acid, type 2 diabetes, metabolic disorders, inflammation, gout, autoinflammatory disease, high-fat diet
- MeSH terms
- NLR Family, Pyrin Domain-Containing 3 Protein, beta-Arrestins, beta-Arrestin 2, Animals, Carrier Proteins, Cells, Cultured, Diabetes Mellitus, Type 2, Docosahexaenoic Acids, Enzyme Activation, Inflammation, Macrophages, Mice, Inbred C57BL, Eicosapentaenoic Acid, Fatty Acids, Omega-3, Mice, Knockout, Arrestins, Caspase 1, Receptors, G-Protein-Coupled, Mice, Interleukin-1beta, Inflammasomes, Diet, High-Fat
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
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