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Cited by 122Cognitive Functions and MemoryTreatment of Major DepressionAnxiety, Depression, Psychometrics, Treatment, Cognitive Processes

Cognitive training in affective disorders improves memory: A preliminary study using the NEAR approach

Naismith, Sharon L., Redoblado-Hodge, M. Antoinette, Lewis, Simon J.G., Scott, Elizabeth M., Hickie, Ian B.·2010·Journal of Affective Disorders
DOI 10.1016/j.jad.2009.06.028
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Abstract

Background Neuropsychological deficits in depression include difficulties with psychomotor speed, executive functions and memory. Some of these changes persist despite antidepressant treatment. While research in other areas of psychiatry has shown cognitive training techniques to be effective, only one study has evaluated this approach in depression.Methods Sixteen patients (mean age=33.5years) with a lifetime diagnosis of major depressive disorder were administered a standardised battery of neuropsychological tests and allocated to treatment (n=8) or waitlist control (n=8) conditions. The treatment consisted of 10-weeks of twice weekly cognitive training using the Neuropsychological Educational Approach to Remediation. All participants were re-assessed after 10-weeks by interviewers blinded to group allocation.Results Participants in the treatment condition demonstrated greater improvements on tests of memory encoding and memory retention than the waitlist control group. There were no observable benefits in terms of psychomotor speed or executive functions or in self-reported levels of disability. Affective symptoms also remained stable.Limitations This study included a small sample of participants and treatment allocation was not randomised.Conclusions Cognitive training in affective disorders improves memory performance. It may be an effective non-pharmacological treatment option for improving cognitive functions, which in turn, may improve psychosocial functioning and reduce disability. This study supports theories suggesting cognitive training may promote neuroplasticity.

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  • Data from studies evaluating the impact of cognitive remediation therapy on cognitive performance in major depressive disorder indicate a positive effect on neuropsychological tasks of attention, verbal learning and memory, psychomotor speed, and executive function.

    “For example, data from studies evaluating the impact of cognitive remediation therapy on cognitive performance in MDD indicate a positive effect on neuropsychological tasks of attention, verbal learning and memory, psychomotor speed, and executive function [189, 190].”

    From Cognitive remission: a novel objective for the treatment of major depression? (2016) · cites this paper as [190]

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Authors
Naismith, S. L., Redoblado-Hodge, M. A., Lewis, S. J. G., Scott, E. M., & Hickie, I. B.
Affiliations
The University of Sydney (AU)
Corresponding author
Naismith, Sharon L.
ORCID
Venue
Journal of Affective Disorders
Publisher
Elsevier BV
Published
2010-03
Volume
121
Issue
3
Pages
258-262
ISSN
0165-0327 (ISSN-L)
DOI
10.1016/j.jad.2009.06.028
OpenAlex
W2064581735
Cited by
122
References
20
Citations by year
2026: 1 · 2025: 3 · 2024: 4 · 2023: 1 · 2022: 1 · 2021: 4 · 2020: 5 · 2019: 8 · 2018: 8 · 2017: 6 · 2016: 16 · 2015: 17 · 2014: 11 · 2013: 12 · 2012: 9
FWCI
10.58
Type
journal article
Language
en
Open access
closed
Licence
www.elsevier.com/tdm/userlicense/1.0/ (tdm)
Locations
  • Journal of Affective Disorders (publishedVersion)
  • PubMed (publishedVersion)
Funders
University of Sydney
Topics
  • Social Sciences › Psychology › Experimental and Cognitive Psychology › Cognitive Functions and Memory
  • Health Sciences › Medicine › Pharmacology › Treatment of Major Depression
  • Social Sciences › Psychology › Experimental and Cognitive Psychology › Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
Keywords
cognitive training, major depressive disorder, memory, neuropsychological deficits, memory encoding, memory retention, psychomotor speed, executive function, neuroplasticity, non-pharmacological treatment, cognitive remediation
MeSH terms
Adult, Cognition Disorders, Combined Modality Therapy, Depressive Disorder, Major, Major Depressive Disorder, Female, Follow-Up Studies, Humans, Male, Middle Aged, Neuropsychological Tests, Personality Inventory, Psychometrics, Psychomotor Performance, Psychotropic Drugs, Reaction Time, Mental Recall, Remedial Teaching, Retention, Psychology, Treatment Outcome, Executive Function

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