Perspective: Protein supplementation in frail older persons: Often necessary but not always sufficient
Open accessThe claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
The need for PS in sarcopenic or frail older individuals to overcome a blunted anabolic response to diet protein remains uncertain because of potential confounding factors such as deficit energy metabolism and mitochondrial dysfunction.
“the need for PS in sarcopenic or frail older individuals to overcome a blunted anabolic response to diet protein remains uncertain because of the potential confounding factors involved, such as deficit energy metabolism and mitochondrial dysfunction, which may influence the PS efficacy [82,83]”
From Effects of Protein Supplementation Combined with Exercise Intervention on Frailty Indices, Body Composition, and Physical Function in Frail Older Adults (2018) · cites this paper as [82]
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Cites
Frailty in Older Adults: Evidence for a Phenotype
Fried, L. P., Tangen, C. M., Walston, J., Newman, A. B., Hirsch, C., Gottdiener, J., Seeman, T., Tracy, R., Kop, W. J., Burke, G., et al. (2001) · The Journals of Gerontology Series A: Biological Sciences and Medical Sciences · doi:10.1093/gerona/56.3.m146 · Cited by 24,907 · see citing works
Frailty in relation to the accumulation of deficits
Rockwood, K., & Mitnitski, A. (2007) · The Journals of Gerontology Series A: Biological Sciences and Medical Sciences · doi:10.1093/gerona/62.7.722 · Cited by 3,076 · see citing works
Progressive resistance strength training for improving physical function in older adults
Liu, C.-J., & Latham, N. K. (2009) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd002759.pub2 · Cited by 1,258 · see citing works
Sarcopenia with limited mobility: an international consensus
Morley, J. E., Abbatecola, A. M., Argiles, J. M., Baracos, V., Bauer, J., Bhasin, S., Cederholm, T., Stewart Coats, A. J., Cummings, S. R., Evans, W. J., et al. (2011) · Journal of the American Medical Directors Association · doi:10.1016/j.jamda.2011.04.014 · Cited by 1,125 · see citing works
Protein and energy supplementation in elderly people at risk from malnutrition
Milne, A. C., Potter, J., Vivanti, A., & Avenell, A. (2009) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd003288.pub3 · Cited by 849 · see citing works
Volpi, E., Kobayashi, H., Sheffield-Moore, M., Mittendorfer, B., & Wolfe, R. R. (2003) · The American Journal of Clinical Nutrition · doi:10.1093/ajcn/78.2.250 · Cited by 846 · see citing works
Sarcopenia: characteristics, mechanisms and functional significance
Narici, M. V., & Maffulli, N. (2010) · British Medical Bulletin · doi:10.1093/bmb/ldq008 · Cited by 827 · see citing works
The Effects of High Protein Diets on Thermogenesis, Satiety and Weight Loss: A Critical Review
Halton, T. L., & Hu, F. B. (2004) · Journal of the American College of Nutrition · doi:10.1080/07315724.2004.10719381 · Cited by 822 · see citing works
Nutritional recommendations for the management of sarcopenia
Morley, J. E., Argiles, J. M., Evans, W. J., Bhasin, S., Cella, D., Deutz, N. E. P., Doehner, W., Fearon, K. C. H., Ferrucci, L., Hellerstein, M. K., et al. (2010) · Journal of the American Medical Directors Association · doi:10.1016/j.jamda.2010.04.014 · Cited by 664 · see citing works
Aging, frailty and age-related diseases
Fülöp, T., Larbi, A., Witkowski, J. M., McElhaney, J. E., Loeb, M. B., Mitnitski, A., & Pawelec, G. (2010) · Biogerontology · doi:10.1007/s10522-010-9287-2 · Cited by 651 · see citing works
Tieland, M., Dirks, M. L., van der Zwaluw, N., Verdijk, L. B., van de Rest, O., de Groot, L. C. P. G. M., & van Loon, L. J. C. (2012) · Journal of the American Medical Directors Association · doi:10.1016/j.jamda.2012.05.020 · Cited by 556 · see citing works
Low Nutrient Intake Is an Essential Component of Frailty in Older Persons
Bartali, B., Frongillo, E. A., Bandinelli, S., Lauretani, F., Semba, R. D., Fried, L. P., & Ferrucci, L. (2006) · The Journals of Gerontology Series A · doi:10.1093/gerona/61.6.589 · Cited by 495 · see citing works
Amino acid ingestion improves muscle protein synthesis in the young and elderly
Paddon-Jones, D., Sheffield-Moore, M., Zhang, X.-J., Volpi, E., Wolf, S. E., Aarsland, A., Ferrando, A. A., & Wolfe, R. R. (2004) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.00368.2003 · Cited by 467 · see citing works
Tieland, M., van de Rest, O., Dirks, M. L., van der Zwaluw, N., Mensink, M., van Loon, L. J. C., & de Groot, L. C. P. G. M. (2012) · Journal of the American Medical Directors Association · doi:10.1016/j.jamda.2012.07.005 · Cited by 446 · see citing works
Ryanodine receptor oxidation causes intracellular calcium leak and muscle weakness in aging
Andersson, D. C., Betzenhauser, M. J., Reiken, S., Meli, A. C., Umanskaya, A., Xie, W., Shiomi, T., Zalk, R., Lacampagne, A., & Marks, A. R. (2011) · Cell Metabolism · doi:10.1016/j.cmet.2011.05.014 · Cited by 424 · see citing works
Insulin resistance of muscle protein metabolism in aging
Rasmussen, B. B., Fujita, S., Wolfe, R. R., Mittendorfer, B., Roy, M., Rowe, V. L., & Volpi, E. (2006) · The FASEB Journal · doi:10.1096/fj.05-4607fje · Cited by 402 · see citing works
In Search of an Integral Conceptual Definition of Frailty: Opinions of Experts
Gobbens, R. J. J., Luijkx, K. G., Wijnen-Sponselee, M. T., & Schols, J. M. G. A. (2010) · Journal of the American Medical Directors Association · doi:10.1016/j.jamda.2009.09.015 · Cited by 392 · see citing works
Drummond, M. J., Dreyer, H. C., Pennings, B., Fry, C. S., Dhanani, S., Dillon, E. L., Sheffield‐Moore, M., Volpi, E., & Rasmussen, B. B. (2008) · Journal of Applied Physiology · doi:10.1152/japplphysiol.00021.2008 · Cited by 391 · see citing works
Anorexia, sarcopenia, and aging
Morley, J. E. (2001) · Nutrition · doi:10.1016/s0899-9007(01)00574-3 · Cited by 276 · see citing works
Solerte, S. B., Gazzaruso, C., Bonacasa, R., Rondanelli, M., Zamboni, M., Basso, C., Locatelli, E., Schifino, N., Giustina, A., & Fioravanti, M. (2008) · The American Journal of Cardiology · doi:10.1016/j.amjcard.2008.03.004 · Cited by 235 · see citing works
Aberrant mitochondrial homeostasis in the skeletal muscle of sedentary older adults
Safdar, A., Hamadeh, M. J., Kaczor, J. J., Raha, S., deBeer, J., & Tarnopolsky, M. A. (2010) · PLoS ONE · doi:10.1371/journal.pone.0010778 · Cited by 217 · see citing works
Baldwin, C., & Weekes, C. E. (2011) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd002008.pub4 · Cited by 193 · see citing works
Undernutrition in older adults
Morley, J. E. (2012) · Family Practice · doi:10.1093/fampra/cmr054 · Cited by 193 · see citing works
Kim, C.-O., & Lee, K.-R. (2013) · The Journals of Gerontology Series A: Biological Sciences and Medical Sciences · doi:10.1093/gerona/gls167 · Cited by 184 · see citing works
Magnesium and muscle performance in older persons: the InCHIANTI study
Dominguez, L. J., Barbagallo, M., Lauretani, F., Bandinelli, S., Bós, Â. J. G., Corsi, A. M., Simonsick, E. M., & Ferrucci, L. (2006) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/84.1.419 · Cited by 166 · see citing works
Self-citationFrailty, inflammation and the elderly
Hubbard, R. E., & WOODHOUSE, K. W. (2010) · Biogerontology · doi:10.1007/s10522-010-9292-5 · Cited by 156 · see citing works
Timmerman, K. L., Lee, J. L., Fujita, S., Dhanani, S., Dreyer, H. C., Fry, C. S., Drummond, M. J., Sheffield-Moore, M., Rasmussen, B. B., & Volpi, E. (2010) · Diabetes · doi:10.2337/db10-0415 · Cited by 149 · see citing works
The Early History of the Biochemistry of Muscle Contraction
Szent‐Györgyi, A. G. (2004) · The Journal of General Physiology · doi:10.1085/jgp.200409091 · Cited by 146 · see citing works
Timmerman, K. L., Dhanani, S., Glynn, E. L., Fry, C. S., Drummond, M. J., Jennings, K., Rasmussen, B. B., & Volpi, E. (2012) · American Journal of Clinical Nutrition · doi:10.3945/ajcn.111.020800 · Cited by 138 · see citing works
Magnesium and muscle performance in older persons: The InCHIANTI study
Dominguez, L. J., Barbagallo, M., Lauretani, F., Bandinelli, S., Bos, A., Corsi, A. M., Simonsick, E. M., & Ferrucci, L. (2006) · The American Journal of Clinical Nutrition · doi:10.1093/ajcn/84.2.419 · Cited by 136 · see citing works
Self-citationFrailty: Diagnosis and management
Morley, J. E. (2011) · The journal of nutrition health & aging · doi:10.1007/s12603-011-0338-4 · Cited by 91 · see citing works
A correspondence analysis revealed frailty deficits aggregate and are multidimensional
Sourial, N., Wolfson, C., Bergman, H., Zhu, B., Karunananthan, S., Quail, J., Fletcher, J., Weiss, D., Bandeen-Roche, K., & Béland, F. (2010) · Journal of Clinical Epidemiology · doi:10.1016/j.jclinepi.2009.08.007 · Cited by 85 · see citing works
Frailty amplifies the effects of aging on protein metabolism: role of protein intake
Chevalier, S., Gougeon, R., Nayar, K., & Morais, J. A. (2003) · The American Journal of Clinical Nutrition · doi:10.1093/ajcn/78.3.422 · Cited by 82 · see citing works
Age-Related Changes in Intramyocellular Lipid in Humans by in vivo 1H-MR Spectroscopy
Nakagawa, Y., Hattori, M., Harada, K., Shirase, R., Bando, M., & OKANO, G. (2007) · Gerontology · doi:10.1159/000100869 · Cited by 68 · see citing works
From ‘protein’ to the beginnings of clinical proteomics
Perrett, D. I. (2007) · PROTEOMICS - CLINICAL APPLICATIONS · doi:10.1002/prca.200700525 · Cited by 36 · see citing works
Tinetti, M. E., & Brach, J. S. (2012) · Annals of Internal Medicine · doi:10.7326/0003-4819-157-3-201208070-00014 · Cited by 16 · see citing works
Flagged first, then by citations
Research works printed but not linked: 1
- Ligia J. Dominguez, MD Mario Barbagallo, MD Geriatric Unit, Department of Internal Medicine and Medical Specialties University of Palermo Palermo, Italy http://dx.doi.org/10.1016/j.jamda.2012.09.029 Perspective: Exercise and Protein Supplementation in Frail Elders · DOI
Cited by
Sorted by citations
Coelho‐Júnior, H. J., Rodrigues, B., Uchida, M. C., & Marzetti, E. (2018) · Nutrients · doi:10.3390/nu10091334 · Cited by 176 · see citing works
Liao, C.-D., Lee, P.-H., Hsiao, D.-J., Huang, S.-W., Tsauo, J.-Y., Chen, H.-C., & Liou, T.-H. (2018) · Nutrients · doi:10.3390/nu10121916 · Cited by 94 · see citing works
The relevance of nutrition for the concept of cognitive frailty
Dominguez, L. J., & Barbagallo, M. (2016) · Current Opinion in Clinical Nutrition & Metabolic Care · doi:10.1097/mco.0000000000000337 · Cited by 68 · see citing works
Self-citationGade, J., Beck, A. M., Andersen, H. E., Christensen, B., Rønholt, F., Klausen, T. W., Vinther, A., & Astrup, A. V. (2019) · British Journal Of Nutrition · doi:10.1017/s0007114519001831 · Cited by 33 · see citing works
Cermak, N. M., de Groot, C. P. G. M., & van Loon, L. J. C. (2012) · Journal of the American Medical Directors Association · doi:10.1016/j.jamda.2012.10.003 · Cited by 18 · see citing works
The Multidomain Nature of Malnutrition in Older Persons.
Domínguez, L., & Barbagallo, M. (2017) · Journal of the American Medical Directors Association · doi:10.1016/j.jamda.2017.08.016 · Cited by 14 · see citing works
Self-citationCognitive frailty: a brief review
Petridou, E. (2020) · Journal of Research and Practice on the Musculoskeletal System · doi:10.22540/jrpms-04-113 · Cited by 7 · see citing works
Dietary Protein and Muscle in Aging People
Cesari, M., & Marzetti, E. (2018) · MDPI eBooks · doi:10.3390/books978-3-03897-458-1
- Authors
- Dominguez, L. J., & Barbagallo, M.
- Affiliations
- University of Palermo (IT)
- Venue
- Journal of the American Medical Directors Association
- Publisher
- Elsevier BV
- Published
- 2013-01
- Volume
- 14
- Issue
- 1
- Pages
- 72-73
- ISSN
- 1525-8610 (ISSN-L)
- OpenAlex
- W2137098312
- Cited by
- 9
- References
- 36
- Citations by year
- 2020: 1 · 2019: 1 · 2018: 4 · 2017: 1 · 2016: 1 · 2012: 1
- Type
- journal article
- Language
- en
- Open access
- green
- hdl.handle.net
- Licence
- Locations
- Journal of the American Medical Directors Association (publishedVersion)
- PubMed (publishedVersion)
- Nova Science Publishers (Nova Science Publishers, Inc.) (submittedVersion, other-oa)
- Topics
- Health Sciences › Medicine › Physiology › Nutrition and Health in Aging
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Cell Biology › Muscle metabolism and nutrition
- Health Sciences › Medicine › Geriatrics and Gerontology › Frailty in Older Adults
- Keywords
- protein supplementation, frail elderly, aging, protein nutrition, sarcopenia, muscle protein synthesis, elderly nutrition
- MeSH terms
- Dietary Proteins, Female, Humans, Male, Frail Elderly, Muscle, Skeletal, Dietary Supplements, Muscle Strength, Resistance Training
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
