Minority inclusion in randomized clinical trials of panic disorder

Mendoza, Dorian B.; Williams, Monnica T.; Chapman, L. Kevin; Powers, Mark

doi:10.1016/j.janxdis.2012.02.011

Cited by 70Ethics in Clinical ResearchAnxiety, Depression, Psychometrics, Treatment, Cognitive ProcessesMental Health Treatment and Access

Minority inclusion in randomized clinical trials of panic disorder

Mendoza, Dorian B., Williams, Monnica T., Chapman, L. Kevin, Powers, Mark·2012·Journal of Anxiety Disorders

DOI 10.1016/j.janxdis.2012.02.011

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Abstract

In 1993, the National Institutes of Health issued a mandate that funded research must include participation by racial and ethnic minority groups, and researchers were required to include in their proposals strategies by which they would achieve diversity in their samples. A methodological search for randomized clinical trials of panic disorder was conducted to evaluate ethnoracial differences in panic disorder symptoms, rates of minority inclusion in North American studies, and effective methods of minority recruitment. Less than half of the studies identified reported ethnic and racial data for their sample. Of the 21 studies that did report this information (n=2687), 82.7% were European American/non-Hispanic White, 4.9% were African American/Black, 3.4% were Hispanic, 1.1% were Asian American, and 1.4% were another ethnicity. The remaining 6.5% was simply classified as other/non-White. The primary recruitment techniques utilized were clinical referral and advertising, but neither of these methods were correlated with improved minority participation, nor was the number of recruitment sites. As minorities are greatly underrepresented in panic disorder studies, reported treatment outcomes may not generalize to all ethnic and cultural groups. Researchers have not followed NIH guidelines regarding inclusion of special populations. Inclusion of minorities in future studies is needed to fully understand issues related to the treatment of panic disorder in non-White populations. Su…

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Mental health clinical trial reviews consistently find Latinos underrepresented.
“However, despite the National Institutes of Health requirement of sufficient inclusion of racial minority groups in their funded clinical trials, systematic reviews of mental health clinical trials show consistently low representation of Latinos (Benuto, Bennett, & Casas, 2020; Mendoza, Williams, Chapman, & Powers, 2012; Williams, Powers, Yun, & Foa, 2010).”
From Randomized pilot trial of cognitive-behavioral therapy and acceptance-based behavioral therapy in the treatment of Spanish-speaking Latino primary care patients with generalized anxiety disorder (2021) · cites this paper as Mendoza, Williams, Chapman, & Powers, 2012

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Appendices
Ong, C. W., & Lee, E. B. (2025) · Oxford University Press eBooks · doi:10.1093/oso/9780197696378.005.0001
What Is Process-Based Therapy?
Ong, C. W., & Lee, E. B. (2025) · Oxford University Press eBooks · doi:10.1093/oso/9780197696378.003.0002
Next Steps
Ong, C. W., & Lee, E. B. (2025) · Oxford University Press eBooks · doi:10.1093/oso/9780197696378.003.0009
List of Figures
Ong, C. W., & Lee, E. B. (2025) · Oxford University Press eBooks · doi:10.1093/oso/9780197696378.002.0006
Treatment Planning
Ong, C. W., & Lee, E. B. (2025) · Oxford University Press eBooks · doi:10.1093/oso/9780197696378.003.0006
Decision Making in Treatment
Ong, C. W., & Lee, E. B. (2025) · Oxford University Press eBooks · doi:10.1093/oso/9780197696378.003.0007
Dedication
Ong, C. W., & Lee, E. B. (2025) · Oxford University Press eBooks · doi:10.1093/oso/9780197696378.002.0004
Intake Interview
Ong, C. W., & Lee, E. B. (2025) · Oxford University Press eBooks · doi:10.1093/oso/9780197696378.003.0004
Putting It Together
Ong, C. W., & Lee, E. B. (2025) · Oxford University Press eBooks · doi:10.1093/oso/9780197696378.003.0008
List of Tables
Ong, C. W., & Lee, E. B. (2025) · Oxford University Press eBooks · doi:10.1093/oso/9780197696378.002.0007
The Big Picture
Ong, C. W., & Lee, E. B. (2025) · Oxford University Press eBooks · doi:10.1093/oso/9780197696378.003.0001
A Process-Based Approach to Psychotherapy
Ong, C. W., & Lee, E. B. (2025) · doi:10.1093/oso/9780197696378.001.0001
Network Case Conceptualization
Ong, C. W., & Lee, E. B. (2025) · Oxford University Press eBooks · doi:10.1093/oso/9780197696378.003.0005
The Five Principles of PBT
Ong, C. W., & Lee, E. B. (2025) · Oxford University Press eBooks · doi:10.1093/oso/9780197696378.003.0003
Copyright Page
Ong, C. W., & Lee, E. B. (2025) · Oxford University Press eBooks · doi:10.1093/oso/9780197696378.002.0003

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Authors: Mendoza, D. B., Williams, M. T., Chapman, L. K., & Powers, M.
Affiliations: University of Pennsylvania (US)
University of Louisville (US)
Southern Methodist University (US)
Corresponding author: Williams, Monnica T.
ORCID: Williams, Monnica T.
Powers, Mark
Venue: Journal of Anxiety Disorders
Publisher: Elsevier BV
Published: 2012-06
Volume: 26
Issue: 5
Pages: 574-582
ISSN: 0887-6185 (ISSN-L)
DOI: 10.1016/j.janxdis.2012.02.011
OpenAlex: W2158293741
Cited by: 70
References: 87
Citations by year: 2025: 18 · 2024: 7 · 2023: 6 · 2022: 3 · 2021: 2 · 2020: 4 · 2019: 5 · 2018: 4 · 2017: 4 · 2016: 6 · 2015: 4 · 2014: 4 · 2013: 3
FWCI: 0.55
Type: journal article
Language: en
Open access: closed
Licence: www.elsevier.com/tdm/userlicense/1.0/ (tdm)
www.elsevier.com/legal/tdmrep-license (tdm)
Locations: Journal of Anxiety Disorders (publishedVersion)
PubMed (publishedVersion)
Topics: Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Ethics in Clinical Research
Social Sciences › Psychology › Experimental and Cognitive Psychology › Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
Social Sciences › Psychology › Social Psychology › Mental Health Treatment and Access
Keywords: panic disorder, racial and ethnic minorities, minority recruitment, underrepresentation in clinical trials, recruitment strategies, clinical referral
MeSH terms: Asian, Black or African American, Hispanic or Latino, Humans, Research Design, Randomized Controlled Trials as Topic, Panic Disorder, Patient Selection

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Minority inclusion in randomized clinical trials of panic disorder

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