Glycemic Management Across the Lifespan for People With Type 1 Diabetes: A Clinical Practice Guideline

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Clinical Targets for Continuous Glucose Monitoring Data Interpretation: Recommendations From the International Consensus on Time in Range

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State of Type 1 Diabetes Management and Outcomes from the T1D Exchange in 2016–2018

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Six-Month Randomized, Multicenter Trial of Closed-Loop Control in Type 1 Diabetes

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Intensive diabetes treatment and cardiovascular outcomes in type 1 diabetes: The DCCT/EDIC study 30-year follow-up

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Consensus Recommendations for the Use of Automated Insulin Delivery Technologies in Clinical Practice

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Teplizumab improves and stabilizes beta cell function in antibody-positive high-risk individuals

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Efficacy and safety of a fixed-ratio combination of insulin degludec and liraglutide (IDegLira) compared with its components given alone: results of a phase 3, open-label, randomised, 26-week, treat-to-target trial in insulin-naive patients with type 2 diabetes

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Racial-ethnic disparities in management and outcomes among children with type 1 diabetes

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Empagliflozin as Adjunctive to Insulin Therapy in Type 1 Diabetes: The EASE Trials

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Cardiovascular and metabolic effects of metformin in patients with type 1 diabetes (REMOVAL): a double-blind, randomised, placebo-controlled trial

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Cognitive Function in Children With Type 1 Diabetes

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Efficacy and safety of liraglutide added to insulin treatment in type 1 diabetes: the ADJUNCT ONE treat-to-target randomized trial

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Diabetes distress among adolescents with type 1 diabetes: a systematic review

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Multicenter trial of a tubeless, on-body automated insulin delivery system with customizable glycemic targets in pediatric and adult participants with type 1 diabetes

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A Decade of Disparities in Diabetes Technology Use and HbA1c in Pediatric Type 1 Diabetes: A Transatlantic Comparison

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Short acting insulin analogues versus regular human insulin in patients with diabetes mellitus

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ISPAD Clinical Practice Consensus Guidelines 2022: Glycemic targets and glucose monitoring for children, adolescents, and young people with diabetes

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Efficacy and safety of liraglutide added to capped insulin treatment in subjects with type 1 diabetes: The adjunct two randomized trial

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0.9% saline versus Plasma-Lyte as initial fluid in children with diabetic ketoacidosis (SPinK trial): a double-blind randomized controlled trial

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Efficacy and Safety of Dapagliflozin in Patients With Inadequately Controlled Type 1 Diabetes (the DEPICT-2 Study): 24-Week Results From a Randomized Controlled Trial

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Efficacy and safety of dapagliflozin in patients with inadequately controlled type 1 diabetes: the DEPICT-1 52-week study

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Efficacy and safety of insulin analogues for the management of diabetes mellitus: a meta-analysis

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Sotagliflozin in combination with optimized insulin therapy in adults with type 1 diabetes: the North American inTandem1 Study

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Safety and Glycemic Outcomes During the MiniMed™ Advanced Hybrid Closed-Loop System Pivotal Trial in Adolescents and Adults with Type 1 Diabetes

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Clinical Trial of Fluid Infusion Rates for Pediatric Diabetic Ketoacidosis

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Baricitinib and β-cell function in patients with new-onset type 1 diabetes

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Trial of Hybrid Closed-Loop Control in Young Children with Type 1 Diabetes

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HbA1c and Hypoglycemia Reductions at 24 and 52 Weeks With Sotagliflozin in Combination With Insulin in Adults With Type 1 Diabetes: The European inTandem2 Study

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Anti-interleukin-21 antibody and liraglutide for the preservation of β-cell function in adults with recent-onset type 1 diabetes: A randomised, double-blind, placebo-controlled, phase 2 trial

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Open-source automated insulin delivery in type 1 diabetes

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Racial–Ethnic Disparities in Diabetes Technology use Among Young Adults with Type 1 Diabetes

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Effect of Verapamil on Pancreatic Beta Cell Function in Newly Diagnosed Pediatric Type 1 Diabetes: A Randomized Clinical Trial

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Frequency and Timing of Severe Hypoglycemia Affects Spatial Memory in Children With Type 1 Diabetes

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Diabetes distress is linked with worsening diabetes management over time in adults with type 1 diabetes

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Optimal prandial timing of bolus insulin in diabetes management: a review

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Efficacy and safety of suspend-before-low insulin pump technology in hypoglycaemia-prone adults with type 1 diabetes (SMILE): an open-label randomised controlled trial

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Comparison of Insulin Glargine 300 Units/mL and 100 Units/mL in Adults With Type 1 Diabetes: Continuous Glucose Monitoring Profiles and Variability Using Morning or Evening Injections

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Once-weekly insulin icodec versus once-daily insulin degludec as part of a basal-bolus regimen in individuals with type 1 diabetes (ONWARDS 6): a phase 3a, randomised, open-label, treat-to-target trial

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Sodium‐glucose co‐transporter inhibitors, their role in type 1 diabetes treatment and a risk mitigation strategy for preventing diabetic ketoacidosis: The STOP DKA Protocol

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Continuous subcutaneous insulin infusion versus multiple daily injections in individuals with type 1 diabetes: A systematic review and meta-analysis

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Impact of Type 1 Diabetes in the Developing Brain in Children: A Longitudinal Study

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A Meta-Analysis of Randomized Trial Outcomes for the t:slim X2 Insulin Pump with Control-IQ Technology in Youth and Adults from Age 2 to 72

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A clinical guide to advanced diabetes devices and closed-loop systems using the CARES paradigm

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Automated Insulin Delivery Systems in Children and Adolescents With Type 1 Diabetes: A Systematic Review and Meta-analysis of Outpatient Randomized Controlled Trials

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Hybrid closed‐loop glucose control with faster insulin aspart compared with standard insulin aspart in adults with type 1 diabetes: A double‐blind, multicentre, multinational, randomized, crossover study

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Insulin Glulisine Compared to Insulin Aspart and to Insulin Lispro Administered by Continuous Subcutaneous Insulin Infusion in Patients with Type 1 Diabetes: A Randomized Controlled Trial

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Hybrid Closed-Loop Therapy in Adults With Type 1 Diabetes and Above-Target HbA1c: A Real-world Observational Study

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Short-acting insulin analogues versus regular human insulin for adults with type 1 diabetes mellitus

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The Prognostic Value of Blood Glucose in Diabetic Patients with Acute Myocardial Infarction

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Understanding the construct of fear of hypoglycemia in pediatric type 1 diabetes

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Patient-reported use of collaborative goal setting and glycemic control among patients with diabetes

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Efficacy of Semaglutide in Overweight and Obese Patients with Type 1 Diabetes

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Goal Setting: An Integral Component of Effective Diabetes Care

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Efficacy and Safety of Insulin Glulisine in Patients with Type 1 Diabetes

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Subcutaneous rapid-acting insulin analogues for diabetic ketoacidosis

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Improved Postprandial Glycemic Control with Faster-Acting Insulin Aspart in Patients with Type 1 Diabetes Using Continuous Subcutaneous Insulin Infusion

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Glucagon-like peptide 1 analogues as adjunctive therapy for patients with type 1 diabetes: An updated systematic review and meta-analysis

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Efficacy and Safety of Fast-Acting Insulin Aspart Compared With Insulin Aspart, Both in Combination With Insulin Degludec, in Children and Adolescents With Type 1 Diabetes: The onset 7 Trial

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International comparison of glycaemic control in people with type 1 diabetes: an update and extension

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Improved Glycemia with Hybrid Closed-Loop Versus Continuous Subcutaneous Insulin Infusion Therapy: Results from a Randomized Controlled Trial

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The effect of adding metformin to insulin therapy for type 1 diabetes mellitus children: A systematic review and meta-analysis

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Real-world evidence of automated insulin delivery system use

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Diabetes distress and HbA1c in racially/ethnically and socioeconomically diverse youth with type 1 diabetes

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Effective treatment of hypoglycemia in children with type 1 diabetes: a randomized controlled clinical trial

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Real world use of hybrid‐closed loop in children and young people with type 1 diabetes mellitus—a National Health Service pilot initiative in England

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Efficacy and safety of pramlintide injection adjunct to insulin therapy in patients with type 1 diabetes mellitus: a systematic review and meta-analysis

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Effect of automated insulin delivery systems on person-reported outcomes in people with diabetes: a systematic review and meta-analysis

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Glycemic control, depression, diabetes distress among adolescents with type 1 diabetes: effects of sex, race, insurance, and obesity

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Controlled trial of Hartmann's solution versus 0.9% saline for diabetic ketoacidosis

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Short acting insulin analogues versus regular human insulin in patients with diabetes mellitus

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Comparison of subcutaneous insulin aspart and intravenous regular insulin for the treatment of mild and moderate diabetic ketoacidosis in pediatric patients

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Randomized 52-week phase 2 trial of albiglutide versus placebo in adult patients with newly diagnosed type 1 diabetes

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Safety and Efficacy of Teplizumab for Treatment of Type One Diabetes Mellitus: A Systematic Review and Meta-Analysis

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Effect of smartphone apps on glycemic control in young patients with type 1 diabetes: A meta-analysis

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A randomized crossover study of the efficacy and safety of switching from insulin glargine to insulin degludec in children with type 1 diabetes

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Intranasal versus injectable glucagon for hypoglycemia in type 1 diabetes: Systematic review and meta-analysis

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Sodium–glucose cotransporter inhibitors as add‐on therapy in addition to insulin for type 1 diabetes mellitus: A meta‐analysis of randomized controlled trials

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Efficacy and immunogenicity of insulin biosimilar compared to their reference products: a systematic review and meta-analysis

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Associations between insulin pump self‐management and HbA1c in type 1 diabetes

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Comparing the clinical effects of balanced electrolyte solutions versus normal saline in managing diabetic ketoacidosis

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Performance of Fast-Acting Aspart Insulin as Compared to Aspart Insulin in Insulin Pump for Managing Type 1 Diabetes Mellitus: A Meta-Analysis

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The impact of blood glucose and HbA1c goals on glycaemic control in children and adolescents with Type 1 diabetes

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Effectiveness of Continuous Subcutaneous Insulin Infusion on Parental Quality of Life and Glycemic Control Among Children With T1D: Meta‐Analysis

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Non-Insulin Antidiabetes Treatment in Type 1 Diabetes Mellitus: A Systematic Review and Meta-Analysis

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Optimal Prandial Timing of Insulin Bolus in Youths with Type 1 Diabetes: A Systematic Review

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Effect and Safety of Adding Metformin to Insulin Therapy in Treating Adolescents With Type 1 Diabetes Mellitus: An Updated Meta-Analysis of 10 Randomized Controlled Trials

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Normal Saline Versus Low Chloride Solutions in Treatment of Diabetic Ketoacidosis: A Systematic Review of Clinical Trials

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Factors Associated with Attainment of Glycemic Targets Among Adults with Type 1 and Type 2 Diabetes in Canada: A Cross-Sectional Study Using Primary- and Specialty-Care Electronic Medical Record Data

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Faster insulin action is associated with improved glycaemic outcomes during closed‐loop insulin delivery and sensor‐augmented pump therapy in adults with type 1 diabetes

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Fluids in the treatment of diabetic ketoacidosis in children: A systematic review

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Efficacy and safety among second-generation and other basal insulins in adult patients with type 1 diabetes: a systematic review and network meta-analysis

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Brøsen, J. M. B., Agesen, R. M., Kristensen, P. L., Alibegovic, A. C., Andersen, H. U., Beck‐Nielsen, H., Gustenhoff, P., Hansen, T. K., Hedetoft, C., Jensen, T. J., et al. (2023) · Diabetes Obesity and Metabolism · doi:10.1111/dom.15003 · Cited by 6 · see citing works

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Comparison of Intranasal and Injectable Glucagon Administration Among Pediatric Population Responders

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Fear of hypoglycemia in parents of children with type 1 diabetes trained for intranasal glucagon use

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Social disadvantage and technology use among adults with type 1 diabetes in Quebec: A cross‐sectional study using data from the Canadian <scp>T1D</scp> ( <scp>BETTER</scp> ) Registry

Khodabandehloo, P., Fakembe, P., Senga, J., Shulman, R., Lipscombe, L. L., Witteman, H. O., Banerjee, A., Presseau, J., Nakhla, M., Dogba, M. J., et al. (2025) · Diabetes, Obesity and Metabolism · doi:10.1111/dom.16426 · Cited by 6 · see citing works

Safety and Effectiveness of Subcutaneous Insulin for Management of Mild to Moderate Diabetic Ketoacidosis in Nonpregnant Individuals: A Retrospective Cohort Study at a Tertiary Care Centre

Qiang, J. K., Kiss, A., Yu, W., Amaral, A. C. K.-B., Shelton, D., Notario, L., & Halperin, I. J. (2025) · Canadian Journal of Diabetes · doi:10.1016/j.jcjd.2025.10.173 · Cited by 1 · see citing works

Semaglutide Use With Automated Insulin Delivery in Adults With Type 1 Diabetes: Qualitative Analyses and Patient-reported Outcomes From a Randomized Controlled Trial

Pasqua, M., Doumat, J., Tsoukas, M. A., & Haidar, A. (2025) · Canadian Journal of Diabetes · doi:10.1016/j.jcjd.2025.10.175 · Cited by 1 · see citing works

Timing of insulin pump initiation among individuals with type 1 diabetes in Ontario, Canada

Zhu, X., Lipscombe, L. L., Shulman, R. M., Lovblom, L. E., Everett, K., & Weisman, A. (2026) · Diabetes Obesity and Metabolism · doi:10.1111/dom.70514 · Cited by 1 · see citing works

Efficacy and Management of Automated Insulin Delivery Systems Perioperatively in Type 1 Diabetes: A Scoping Review

Ruprai, B., Catania, S., Berati, V., Halperin, I. J., Malcolm, J., Liu, S., Houlden, R. L., & Spaic, T. (2026) · Canadian Journal of Diabetes · doi:10.1016/j.jcjd.2026.03.002 · Cited by 1 · see citing works

Type 1 Diabetes Mellitus

Azim, S. N. (2026) · Springer eBooks · doi:10.1007/978-3-032-12937-6_13 · Cited by 1 · see citing works

Optimizing the Use of Automated Insulin Delivery (AID) Systems in Routine Clinical Care of People with Type 1 Diabetes

Chambers, A., & Halperin, I. J. (2025) · Canadian Diabetes & Endocrinology Today · doi:10.58931/cdet.2025.3345

Effect of Data Preparation on Machine Learning Models for Diabetes Prediction

Martinović, G., Ivković, I., Verber, D., & Bačun, T. (2026) · doi:10.3390/engproc2026125013

Overall Diagnostic Performance of Multiple Versus Single Physical Examination Tests for the Prediction of Future Diabetic Neuropathy Risk

PARIKH, E., Mulla, A. A., Lovblom, L. E., BUDHRAM, D. R., Orszag, A., Falappa, M., Gad, H., Bril, V., & Perkins, B. A. (2026) · Journal of the Peripheral Nervous System · doi:10.1111/jns.70114

Physical Activity and Quality of Life in Children and Youth With Type 1 Diabetes: A Cross-sectional Analysis

Sideroff, T. C., Wall, N., Gill, S., Smith, T., & Voss, C. (2026) · Canadian Journal of Diabetes · doi:10.1016/j.jcjd.2026.03.005

Harnessing technology and AI-driven innovations in diabetes management: addressing clinical challenges and the rising global burden

Nagar, P., Rashid, M., Arora, S., Alam, S., Agrawal, M., & Basist, P. (2026) · International Journal of Diabetes in Developing Countries · doi:10.1007/s13410-026-01651-w

Barriers and Enablers to Diabetes Technologies Use Among Individuals With Type 1 Diabetes: A Scoping Review

Palermo, L., Senga, J., Fakembe, P., Zhu, X., Walsh, C., Leslie, B., Shulman, R. M., Presseau, J., Dogba, M. J., Banerjee, A., et al. (2026) · Diabetes Obesity and Metabolism · doi:10.1111/dom.70819

Behaviour change techniques and physical activity outcomes in interventions for children with type 1 diabetes: A scoping review

Gill, S., Grieve, N. J., HEERDEN, L. V., Shwed, A., Jun, J., Cohen, T. R., Panagiotopoulos, C., Tang, T. S., Jung, M. E., & Voss, C. (2026) · Diabetes Research and Clinical Practice · doi:10.1016/j.diabres.2026.113321

Beyond Insulin

Ni, H., SNAITH, J. R., & Greenfield, J. R. (2026) · Endocrinology and Metabolism Clinics of North America · doi:10.1016/j.ecl.2026.04.001

Retrospective Real-world Analysis of Insulin Pump and Continuous Glucose Monitoring Technology Utilization in a Large Canadian Type 1 Diabetes Clinic

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The diabetes distress experience from the perspective of adolescents and their parents

Sangha, R., Grieve, N. J., Braaten, K., Gill, S., Yakubu, T., Warshawski, T., Tang, T. S., Smith, T., Jung, M., Haynes, E. M. K., et al. (2026) · Frontiers in Clinical Diabetes and Healthcare · doi:10.3389/fcdhc.2026.1652578

Diabetes Mellitus

Tam, K., & Lund, H. (2026) · Springer eBooks · doi:10.1007/978-3-031-90919-1_22-1

Weight Loss and Body Image Are Not Synonymous: Divergent Effects of Glucagon-Like Peptide-1 Receptor Agonist Therapy and Behavioural Intervention in a Young Adult With Type 1 Diabetes—A Case Report

Patience, N., Ritholz, M. D., SAVORY, M., BRABANT, H., & Toschi, E. (2026) · Canadian Journal of Diabetes · doi:10.1016/j.jcjd.2026.08.002

Prandial Insulin Adjustments in the Context of Gastroparesis and Type 1 Diabetes: A Mixed-Methods Study

Talbo, M. K., Katz, A., Roy‐Fleming, A., Haag, S. C., Peters, T. M., RABASA-LHORET, R. P. R., Yale, J., Kelly, B., Moisan, J. M., & Brazeau, A. (2026) · Canadian Journal of Diabetes · doi:10.1016/j.jcjd.2026.07.006

Glucose Management in Children Living with Type 1 Diabetes: Results from the BETTER Registry

Messier, V., Henderson, M., Nakhla, M. M., Simoneau‐Roy, J., Talbo, M. K., Dervaux, D., Kinnard, N., Vanasse, A., Rekik, M., Rabasa-Lhoret, R. M., et al. (2026) · Hormone Research in Paediatrics · doi:10.1159/hrp/adaag016

The Evolution of Carbohydrate Management in Type 1 Diabetes

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Eating behaviour and glycaemic control: A cross-sectional study in adolescents with diabetes

Şimşekoğlu, N., Arslanoğlu, İ., Portakal, B., & Aktaş, S. (2026) · PLoS ONE · doi:10.1371/journal.pone.0361574

Addendum to “Glycemic Management Across the Lifespan for People With Type 1 Diabetes: A Clinical Practice Guideline” [Can J Diabetes. 2025;49:5–18]

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Glycemic Control in Children and Adolescents with Type 1 Diabetes: From Challenges to Innovation

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Diagnosis, Therapy and Control of Diabetes Mellitus in Children and Adolescents

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Current Management of Type 1 Diabetes in Children: Guideline-based Expert Opinions and Recommendations

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ISPAD Clinical Practice Consensus Guidelines 2022: Stages of type 1 diabetes in children and adolescents

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