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Phenolics and polyphenolics in foods, beverages and spices: Antioxidant activity and health effects –A review
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This review reports on the latest research results and applications of phenolic and polyphenolic compounds. Phenolic compounds, ubiquitous in plants, are an essential part of the human diet and are of considerable interest due to their antioxidant properties and potential beneficial health effects. These compounds range structurally from a simple phenolic molecule to complex high-molecular-weight polymers. There is increasing evidence that consumption of a variety of phenolic compounds present in foods may lower the risk of health disorders because of their antioxidant activity. When added to foods, antioxidants control rancidity development, retard the formation of toxic oxidation products, maintain nutritional quality, and extend the shelf-life of products. Due to safety concerns and limitation on the use of synthetic antioxidants, natural antioxidants obtained from edible materials, edible by-products and residual sources have been of increasing interest. This contribution summarizes both the synthetic and natural phenolic antioxidants, emphasizing their mode of action, health effects, degradation products and toxicology. In addition, sources of phenolic antioxidants are discussed in detail.
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“They exhibit anti-inflammatory, antibacterial, antifungal, antiviral, antiallergic, anticancer and anticoagulant properties [190,191,192,193,197].”
From Bioactive Compounds for Skin Health: A Review (2021) · cites this paper as [192]
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Sprouts and Microgreens: Trends, Opportunities, and Horizons for Novel Research
Galieni, A., Falcinelli, B., Stagnari, F., Datti, A., & Benincasa, P. (2020) · Agronomy · doi:10.3390/agronomy10091424 · Cited by 203
Food flavonols: Nutraceuticals with complex health benefits and functionalities
Barreca, D., Trombetta, D., Smeriglio, A., Mandalari, G., Romeo, O., Felice, M. R., Gattuso, G., & Nabavi, S. M. (2021) · Trends in Food Science & Technology · doi:10.1016/j.tifs.2021.03.030 · Cited by 200
Ayoub, M., de Camargo, A. C., & Shahidi, F. (2015) · Food Chemistry · doi:10.1016/j.foodchem.2015.10.107 · Cited by 188
Zhang, L. H., McClements, D. J., Wei, Z., Wang, G., Liu, X., & Liu, F. (2019) · Critical Reviews in Food Science and Nutrition · doi:10.1080/10408398.2019.1630358 · Cited by 191
“Various types of polyphenols are present in plant-based foods, which vary in their levels, physicochemical characteristics, and nutritional effects (Shahidi and Ambigaipalan 2015).”
BackgroundHow Fermentation Affects the Antioxidant Properties of Cereals and Legumes
Verni, M., Verardo, V., & Rizzello, C. G. (2019) · Foods · doi:10.3390/foods8090362 · Cited by 195
“Today, almost all processed foods contain synthetic antioxidants and, despite being reported safe in the past, several studies have addressed their danger for human health, among which liver, kidney, and lungs damages, mutagenesis, carcinogenesis, and many others [19].”
BackgroundInfluentialPolyphenols in Health and Disease: Gut Microbiota, Bioaccessibility, and Bioavailability
Bié, J., Sepodes, B. M. N., Fernandes, P. C. D. B., & Ribeiro, M. H. L. (2023) · Compounds · doi:10.3390/compounds3010005 · Cited by 208
Veiko, A. G., Olchowik‐Grabarek, E., Sękowski, S., Roszkowska, A., Lapshina, E. A., Dobrzyńska, I., Zamaraeva, M. V., & Zavodnik, I. B. (2023) · Molecules · doi:10.3390/molecules28031252 · Cited by 186
González‐Sarrías, A., Garcı́a-Villalba, R., Núñez‐Sánchez, M. Á., Tomé‐Carneiro, J., Zafrilla, P., Mulero, J., Tomás-Barberán, F. A., & Espı́n, J. C. (2015) · Journal of Functional Foods · doi:10.1016/j.jff.2015.09.019 · Cited by 184
Maschmeyer, T., Luque, R., & Selva, M. (2020) · Chemical Society Reviews · doi:10.1039/c9cs00653b · Cited by 185
Scalable biocatalytic C–H oxyfunctionalization reactions
Chakrabarty, S., Wang, Y., Perkins, J. C., & Narayan, A. R. H. (2020) · Chemical Society Reviews · doi:10.1039/d0cs00440e · Cited by 180
Biochemistry of Antioxidants: Mechanisms and Pharmaceutical Applications
Losada‐Barreiro, S., Bayındır, Z. S., Paiva‐Martins, F., & Bravo‐Díaz, C. (2022) · Biomedicines · doi:10.3390/biomedicines10123051 · Cited by 209
Mocan, A., Zengin, G., Simirgiotis, M. J., Schafberg, M., Mollica, A., Vodnar, D. C., Crișan, G., & Rohn, S. (2017) · Journal of Enzyme Inhibition and Medicinal Chemistry · doi:10.1080/14756366.2016.1243535 · Cited by 177
de Camargo, A. C., Regitano-D’Arce, M. A. B., Biasoto, A. C. T., & Shahidi, F. (2016) · Food Chemistry · doi:10.1016/j.foodchem.2016.05.047 · Cited by 176
Biochemical and Structural Analysis of Substrate Specificity of a Phenylalanine Ammonia-Lyase
Jun, S., Sattler, S. A., Cortez, G. S., Vermerris, W., Sattler, S. E., & Kang, C. (2017) · PLANT PHYSIOLOGY · doi:10.1104/pp.17.01608 · Cited by 175
Arvaniti, O. S., Samaras, Y., Gatidou, G., Τhomaidis, Ν. S., & Stasinakis, A. S. (2019) · Food Research International · doi:10.1016/j.foodres.2019.01.055 · Cited by 173
Lü, F., Kuhnle, G. K., & Cheng, Q. (2018) · Food Control · doi:10.1016/j.foodcont.2018.05.018 · Cited by 171
Yan, C., Jin, J., Wang, J., Zhang, F., Tian, Y., Liu, C., Zhang, F., Cao, L., Zhou, Y., & Han, Q. (2021) · Coordination Chemistry Reviews · doi:10.1016/j.ccr.2022.214595 · Cited by 172
Ge, S., Duo, L., Wang, J., GegenZhula, Yang, J., Li, Z., & Tu, Y. (2021) · Journal of Ethnopharmacology · doi:10.1016/j.jep.2021.113877 · Cited by 168
Moazzen, A., Öztinen, N., Ak-sakallı, E., & Koşar, M. (2022) · Heliyon · doi:10.1016/j.heliyon.2022.e10467 · Cited by 167
“ABTS þ radical cation decolorization assay and 2,2-diphenyl-1-picrylhydrazyl (DPPH ) radical scavenging assay are methods that are based on electron donation of antioxidants to reduce the radical (Shahidi and Ambigaipalan, 2015).”
MethodIsmail, B. B., Pu, Y., Guo, M., Ma, X., & Liu, D. (2018) · Food Chemistry · doi:10.1016/j.foodchem.2018.10.056 · Cited by 166
Bener, M., Şen, F. B., Önem, A. N., Bekdeşer, B., Çeli̇k, S. E., Lalikoğlu, M., Aşçı, Y. S., Çapanoğlu, E., & Apak, R. (2022) · Food Chemistry · doi:10.1016/j.foodchem.2022.132633 · Cited by 169
Fruit Juice Industry Wastes as a Source of Bioactives
Kandemir, K., Piskin, E., Xiao, J., Tomaş, M., & Çapanoğlu, E. (2022) · Journal of Agricultural and Food Chemistry · doi:10.1021/acs.jafc.2c00756 · Cited by 182
Phenolic compounds in agri-food by-products, their bioavailability and health effects
Shahidi, F., Vamadevan, V., Oh, W. Y., & Peng, H. (2019) · Journal of Food Bioactives · doi:10.31665/jfb.2019.5178 · Cited by 175
Martinez-Gomez, A., Caballero, I., & Blanco, C. A. (2020) · Biomolecules · doi:10.3390/biom10030400 · Cited by 164
“The classification of the different phenols is done according to their structure, so we have phenolics acids, flavonoids, stilbenes, coumarins, lignans, tannins, chalcones flavonols, flavononols, flavones, flavanols, flavanones, anthocyanidins and isoflavonoids [49,50].”
BackgroundNatural Antioxidant Evaluation: A Review of Detection Methods
Mendonça, J. D. S., Guimarães, R. D. C. A., Zorgetto-Pinheiro, V. A., Fernandes, C. D. P., Marcelino, G., Bogo, D., Freitas, K. D. C., Hiane, P. A., Melo, E. S. D. P., Vilela, M. L. B., et al. (2022) · Molecules · doi:10.3390/molecules27113563 · Cited by 164
Metadata
- Authors
- Shahidi, F., & Ambigaipalan, P.
- Affiliations
- Memorial University of Newfoundland (CA)
- Corresponding author
- Shahidi, Fereidoon
- Venue
- Journal of Functional Foods
- Publisher
- Elsevier BV
- Published
- 2015-10
- Volume
- 18
- Pages
- 820-897
- ISSN
- 1756-4646 (ISSN-L)
- OpenAlex
- W1174839022
- Cited by
- 3,081
- References
- 950
- Citations by year
- 2026: 376 · 2025: 283 · 2024: 293 · 2023: 315 · 2022: 355 · 2021: 413 · 2020: 314 · 2019: 283 · 2018: 209 · 2017: 144 · 2016: 86 · 2015: 8
- FWCI
- 102.36
- Type
- journal article
- Language
- en
- Open access
- hybrid
- doi.org
- Licence
- Locations
- Journal of Functional Foods (publishedVersion, cc-by-nc-nd)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
- Topics
- Health Sciences › Medicine › Biochemistry (medical) › Phytochemicals and Antioxidant Activities
- Physical Sciences › Chemistry › Organic Chemistry › Edible Oils Quality and Analysis
- Physical Sciences › Chemistry › Organic Chemistry › Free Radicals and Antioxidants
- Keywords
- phenolic compounds, polyphenols, antioxidant activity, natural antioxidants, synthetic antioxidants, dietary antioxidants, beverages, spices, health effects, oxidative degradation products, toxicology, shelf life extension, rancidity prevention, functional foods
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