EASL Clinical Practice Guidelines: Drug-induced liver injury

Andrade, Raúl J., Aithal, Guruprasad P., Björnsson, Einar S., Kaplowitz, Neil, Kullak-Ublick, Gerd A., Larrey, Dominique, Karlsen, Tom H.·2019·Journal of Hepatology
DOI 10.1016/j.jhep.2019.02.014

Cites (371)

Items 201–366 of 366

  1. Female gender as a susceptibility factor for drug-induced liver injury
    David E. Amacher · 2013 · Human & Experimental Toxicology
  2. Assessment of liver fibrosis with transient elastography and FibroTest in patients treated with methotrexate for chronic inflammatory diseases: A case–control study
    David Laharie, Julien Sénéschal, Thierry Schaeverbeke, M.‐S. Doutre, M. Longy‐Boursier, Jean‐Luc Pellegrin, Édouard Chabrun, Sandrine Villars, Frank Zerbib, Victor de Lédinghen · 2010 · Journal of Hepatology
  3. Case Characterization, Clinical Features and Risk Factors in Drug-Induced Liver Injury
    Aida Ortega‐Alonso, Camilla M. Stephens, M. Isabel Lucena, Raúl J. Andrade · 2016 · International Journal of Molecular Sciences
  4. Methyldopa hepatitis
    John S. Rodman, D Deutsch, Steven I. Gutman · 1976 · The American Journal of Medicine
  5. Persistent Liver Biochemistry Abnormalities Are More Common in Older Patients and those With Cholestatic Drug Induced Liver Injury
    Robert J. Fontana, Paul Hideyo Hayashi, Huiman Xie Barnhart, David Erwin Kleiner, K. Rajender Reddy, Naga Chalasani, William M. Lee, Andrew Stolz, Thomas A. Phillips, José Serrano et al. · 2015 · The American Journal of Gastroenterology
  6. Nodular Regenerative Hyperplasia of the Liver Graft After Liver Transplantation
    Edward John Gane, Bernard C Portmann, Romil Saxena, Philip Y.N. Wong, John Keith Ramage, Roger L. Williams · 1994 · Hepatology
  7. Acute liver failure induced by idiosyncratic reaction to drugs: Challenges in diagnosis and therapy
    Shannan R. Tujios, William M. Lee · 2017 · Liver International
  8. The management of anti-tuberculosis drug-induced hepatotoxicity.
    Kemal Tahaoğlu, G Ataç, Tülin Sevim, T Tärün, Özlem Moçin Yazıcıoğlu, Gülbanu Horzum, I Gemci, A Ongel, Nilüfer Kapaklı, Emine Aksoy · 2001 · PubMed
  9. Hepatotoxicity After Immune Checkpoint Inhibitor Therapy in Melanoma: Natural Progression and Management
    Huffman, Brandon M., Kottschade, Lisa A., Kamath, Patrick S., Markovic, Svetomir N. · 2018 · American Journal of Clinical Oncology
  10. Immune-related hepatitis with immunotherapy: Are corticosteroids always needed?
    Marie-Léa Gauci, Barouyr Baroudjian, Charlotte Zeboulon, Cécile Pagès, Nicolas Poté, Olivier Roux, Mohamed Bouattour, Célèste Lebbé · 2018 · Journal of Hepatology
  11. Noncirrhotic portal hypertension in HIV-infected patients: unique clinical and pathological findings
    Eugenia Vispo, Alberto Moreno, Ivana Rita Maida, Pablo Barreiro, Adrián Cuevas, Sonia Albertos, Vincent Soriano · 2010 · AIDS
  12. The association of nonalcoholic steatohepatitis and tamoxifen in patients with breast cancer
    Tom Saphner, Shirley Triest‐Robertson, Hailun Li, P.C. Holzman · 2009 · Cancer
  13. Distinct phenotype of hepatotoxicity associated with illicit use of anabolic androgenic steroids
    Robles‐Diaz, M., Gonzalez‐Jimenez, A., Medina‐Caliz, I., Stephens, C., García‐Cortes, M., García‐Muñoz, B., Ortega‐Alonso, A., Blanco‐Reina, E., Gonzalez‐Grande, R., Jimenez‐Perez, M. et al. · 2015 · Alimentary Pharmacology & Therapeutics
  14. Effects of Alcohol on Other Hepatotoxins
    Hyman J. Zimmerman · 1986 · Alcoholism Clinical and Experimental Research
  15. Antibiotic-associated acute vanishing bile duct syndrome: A pattern associated with severe, prolonged, intrahepatic cholestasis
    Mervyn H. Davies, Rebecca F Harrison, Elwyn Elias, Stefan G. Hübscher · 1994 · Journal of Hepatology
  16. Dilated common bile ducts mimicking choledochal cysts in ketamine abusers.
    S W Wong, K F Lee, John Lin Hieng Wong, Wilson W.C. Ng, Yue S. Cheung, Paul B.S. Lai · 2009 · PubMed
  17. Steroid and Ursodesoxycholic Acid Combination Therapy in Severe Drug-Induced Liver Injury
    Wree, Alexander, Dechêne, Alexander, Herzer, Kerstin, Hilgard, Phillip, Syn, Wing-Kin, Gerken, Guido, Canbay, Ali · 2011 · Digestion
  18. Hepatotoxicity Induced by Herbal and Dietary Supplements
    M. Isabel Lucena, Victor J. Navarro · 2014 · Seminars in Liver Disease
  19. The influence of diet upon liver function tests and serum lipids in healthy male volunteers resident in a Phase I unit
    Lynn Purkins, Edward R. Love, M. D. Eve, C. L. Wooldridge, C. Cowan, Trevor S Smart, P. J. Johnson, Garth Rapeport · 2003 · British Journal of Clinical Pharmacology
  20. Recurrent drug-induced liver injury (DILI) with different drugs in the Spanish Registry: the dilemma of the relationship to autoimmune hepatitis
    Lucena, M.I., Kaplowitz, N., Hallal, H., Castiella, A., García-Bengoechea, M., Otazua, P., Berenguer, M., Fernandez, M.C., Planas, R., Andrade, R.J. · 2011 · Journal of Hepatology
  21. Efficacy and safety of acetylcysteine in “non-acetaminophen” acute liver failure: A meta-analysis of prospective clinical trials
    Jinhua Hu, Qizhi Zhang, Xingye Ren, Ziqin Sun, Qizhen Quan · 2015 · Clinics and Research in Hepatology and Gastroenterology
  22. Monitoring and management of antituberculosis drug induced hepatotoxicity
    Subhash Agal, Rajiv Baijal, SNEHANSHU PRAMANIK, NIKHIL PATEL, Parijat Gupte, Praful M. Kamani, Deepak Narayan Amarapurkar · 2005 · Journal of Gastroenterology and Hepatology
  23. Cholestasis and biliary dilatation associated with chronic ketamine abuse: a case series.
    Robert Lo, Rajesh Krishnamoorthy, Jan Freeman, Andrew Austin · 2011 · PubMed
  24. Drug-induced autoimmune hepatitis: response to corticosteroids and lack of relapse after cessation of steroids
    Björnsson, Einar Stefan, Bergmann, Ottar, Jonasson, Jon Gunnlaugur, Grondal, Gerdur, Gudbjornsson, Björn, Olafsson, Sigurdur · 2017 · Clinical Gastroenterology and Hepatology
  25. Formation of a Novel Quinone Epoxide Metabolite of Troglitazone with Cytotoxic to HepG2 Cells
    Yui Yamamoto, Hiroshi Yamazaki, Tomoko Ikeda, Terumi Watanabe, Haruo Iwabuchi, Miki Nakajima, Tsuyoshi Yokoi · 2002 · Drug Metabolism and Disposition
  26. Gynura root induces hepatic veno-occlusive disease: A case report and review of the literature
    Ning Dai · 2007 · World Journal of Gastroenterology
  27. Pharmacogenomics of drug-induced liver injury (DILI): Molecular biology to clinical applications
    Kalaiyarasi Kaliyaperumal, Jane I. Grove, Robin M. Delahay, William J. Griffiths, Adam Duckworth, Guruprasad Padur Aithal · 2018 · Journal of Hepatology
  28. The value of serum aspartate aminotransferase and gamma‐glutamyl transpetidase as biomarkers in hepatotoxicity
    Mercedes Robles‐Díaz, Miren García‐Cortés, Inmaculada Medina‐Cáliz, Andres Gonzalez-Jimenez, Rocío González‐Grande, José María Navarro, Agustín Castiella, Eva M. Zapata, Manuel Romero‐Gómez, Sonia Blanco et al. · 2015 · Liver International
  29. Biochemical and biophysical assessment of MTX‐induced liver fibrosis in psoriasis patients: Fibrotest predicts the presence and Fibroscan® predicts the absence of significant liver fibrosis
    Maartje A. M. Berends, Josje Snoek, Elke M. G. J. de Jong, J. Han van Krieken, Robert Jacobus de Knegt, Martijn G.H. van Oijen, Peter C.M. van de Kerkhof, Joost P.H. Drenth · 2007 · Liver International
  30. Incidence of idiopathic acute liver failure and hospitalized liver injury in patients treated with troglitazone
    David J. Graham, Carol R. Drinkard, Deborah Shatin · 2003 · The American Journal of Gastroenterology
  31. HLA-DRB1*16
    Paola Nicoletti, Anneke Nina Werk, Ashley Sawle, Yufeng Shen, Thomas Jacob Urban, Sally A. Coulthard, Einar Stefan Bjornsson, Ingolf Cascorbi, Aris Floratos, Thomas Stammschulte et al. · 2016 · Pharmacogenetics and Genomics
  32. Transaminase elevation on placebo during Phase I trials: prevalence and significance
    Rosenzweig, Miget, Brohier · 1999 · British Journal of Clinical Pharmacology
  33. Effects of Age and Polytherapy, Risk Factors of Valproic Acid (VPA) Hepatotoxicity, on the Excretion of Thiol Conjugates of (E)‐2,4‐diene VPA in People with Epilepsy Taking VPA
    Sashi Gopaul, K Farrell, Frank S. Abbott · 2003 · Epilepsia
  34. Drug-induced liver injury following positive drug rechallenge
    Julie I. Papay, Dawn C. Clines, Rezvan Rafi, Nancy Yuen, Susan D. Britt, John S.A. Walsh, Christine M. Hunt · 2009 · Regulatory Toxicology and Pharmacology
  35. Hepatitis C and not Hepatitis B virus is a risk factor for anti-tuberculosis drug induced liver injury
    Wan Soo Kim, Sang Soo Lee, Chang Min Lee, Hong-Jun Kim, Chang Yoon Ha, Hyun Jin Kim, Tae Hyo Kim, Woon Tae Jung, Ok‐Jae Lee, Jeong Woo Hong et al. · 2016 · BMC Infectious Diseases
  36. The Latin American DILI Registry Experience: A Successful Ongoing Collaborative Strategic Initiative
    Fernando Bessone, Nelia Hernández, M. Isabel Lucena, Raúl J. Andrade, On behalf of the Latin DILI Network (LATINDILIN) and Spanish DILI Registry · 2016 · International Journal of Molecular Sciences
  37. The Increased Risk of Hospitalizations for Acute Liver Injury in a Population with Exposure to Multiple Drugs
    Susana Perez‐Gutthann, Luis A. Garcia Rodeíguez · 1993 · Epidemiology
  38. Idiosyncratic Drug Induced Liver Injury in African–Americans Is Associated With Greater Morbidity and Mortality Compared to Caucasians
    Chalasani, Naga, Reddy, Rajender K K, Fontana, Robert J, Barnhart, Huiman, Gu, Jiezhun, Hayashi, Paul H, Ahmad, Jawad, Stolz, Andrew, Navarro, Victor, Hoofnagle, Jay H · 2017 · American Journal of Gastroenterology
  39. Predictors of Antiretroviral-Related Hepatotoxicity in the Adult AIDS Clinical Trial Group (1989-1999)
    Julie C. Servoss, Douglas W. Kitch, Janet W. Andersen, Ronald B. Reisler, Raymond T. Chung, Gregory K. Robbins · 2006 · JAIDS Journal of Acquired Immune Deficiency Syndromes
  40. Difficult treatment decisions in autoimmune hepatitis
    Albert J. Czaja · 2010 · World Journal of Gastroenterology
  41. Safety in treatment of hepatocellular carcinoma with immune checkpoint inhibitors as compared to melanoma and non-small cell lung cancer
    Zachary J. Brown, Bernd Heinrich, Seth M. Steinberg, Su Jong Yu, Tim F. Greten · 2017 · Journal for ImmunoTherapy of Cancer
  42. Carbamazepine hepatotoxicity: Another cause of the vanishing bile duct syndrome
    Geoffrey M Forbes, Gary P. Jeffrey, KEITH B. SHILKIN, WILLIAM D REED · 1992 · Gastroenterology
  43. Propylthiouracil, and methimazole, and carbimazole-related hepatotoxicity
    Anam Akmal, Jacqueline Kung · 2014 · Expert Opinion on Drug Safety
  44. Drug rechallenge following drug-induced liver injury
    Hunt, Christine M., Papay, Julie I., Stanulovic, Vid, Regev, Arie · 2017 · Hepatology
  45. A Review of Epidemiologic Research on Drug‐Induced Acute Liver Injury Using the General Practice Research Data Base in the United Kingdom
    Luis Alberto García Rodríguez, Ana Ruigómez, Hershel Jick · 1997 · Pharmacotherapy The Journal of Human Pharmacology and Drug Therapy
  46. Significance of nodular regenerative hyperplasia occurring de novo following liver transplantation
    Harshad C. Devarbhavi, Susan C. Abraham, Patrick S. Kamath · 2007 · Liver Transplantation
  47. Hepatotoxicity associated with statin use: analysis of the cases included in the Spanish Hepatotoxicity Registry.
    Emilia V. Perdices, Inmaculada Medina‐Cáliz, Sofía Hernando, A Ortega, Francisca Martín-Ocaña, José María Navarro, Gloria Isabel Carvajal Peláez, Agustín Castiella, Hacibe Hallal, Manuel Romero‐Gómez et al. · 2014 · PubMed
  48. Pharmacogenetic testing in idiosyncratic drug‐induced liver injury: current role in clinical practice
    Guruprasad Padur Aithal · 2015 · Liver International
  49. Herbal hepatotoxicity: current status, examples, and challenges
    Carlemi Calitz, Du Plessis, Chrisna Gouws, Dewald Steyn, Jan Harm Steenekamp, Christo J. F. Muller, Josias Hendrik Hamman · 2015 · Expert Opinion on Drug Metabolism & Toxicology
  50. Plasma glutathione S-transferase and F protein are more sensitive than alanine aminotransferase as markers of paracetamol (acetaminophen)-induced liver damage.
    Geoffrey J. Beckett, Graham R. Foster, A J Hussey, David B.G. Oliveira, J. Ward Donovan, Laurie F. Prescott, Alex T. Proudfoot · 1989 · Clinical Chemistry
  51. Traditional chinese medicine (TCM) and herbal hepatotoxicity: RUCAM and the role of novel diagnostic biomarkers such as microRNAs
    Teschke, Rolf, Larrey, Dominique, Melchart, Dieter, Danan, Gaby · 2016 · Medicines
  52. Herbal medicine hepatotoxicity: A new step with development of specific biomarkers
    Dominique G. Larrey, Stéphanie Faure · 2010 · Journal of Hepatology
  53. Drug‐induced liver injury associated with stevens‐Johnson syndrome/toxic epidermal necrolysis: Patient characteristics, causes, and outcome in 36 cases
    Harshad C. Devarbhavi, Sujata Raj, Aradya Venu, Vijaykumar T. Rangegowda, Girish P. Veeranna, Rajvir Singh, Vishnuvardan Reddy, Mallikarjun Patil · 2015 · Hepatology
  54. In silicoanalysis of HLA associations with drug-induced liver injury: use of a HLA-genotyped DNA archive from healthy volunteers
    Ana Alfirevic, Faviel F. González-Galarza, Catherine C. Bell, K. Martinsson, Vivien Platt, Giovanna Bretland, Jane Evely, Maike Lichtenfels, Karin Cederbrant, Neil S. French et al. · 2012 · Genome Medicine
  55. Secondary sclerosing cholangitis in critically ill patients: current perspectives
    Gudnason, Hafsteinn O., Björnsson, Einar S · 2017 · Clinical and Experimental Gastroenterology
  56. Associations of Drug Lipophilicity and Extent of Metabolism with Drug-Induced Liver Injury
    Kristin McEuen, Jürgen T. Borlak, Weida Tong, Minjun Chen · 2017 · International Journal of Molecular Sciences
  57. 9 Drug-induced cholestasis
    Dominique G. Larrey, Serge Erlinger · 1988 · Baillière s Clinical Gastroenterology
  58. A comprehensive study of the association between drug hepatotoxicity and daily dose, liver metabolism, and lipophilicity using 975 oral medications
    Zuquan Weng, Kejian Wang, Haibo Li, Qiang Shi · 2015 · Oncotarget
  59. Ramipril-Associated Hepatotoxicity
    Elaine Yeung, Florence Suet-Hing Wong, Ian R. Wanless, Koji Shiota, Maha M. Guindi, Supriya Joshi, Geoffrey W. Gardiner · 2003 · Archives of Pathology & Laboratory Medicine
  60. Comedications alter drug-induced liver injury reporting frequency: Data mining in the WHO VigiBase™
    Ayako Suzuki, Nancy Yuen, Katarina Ilić, Richard Thomas Miller, Melinda J. Reese, Harlan Roger Brown, Jeffrey L. Ambroso, James Greg Falls, Christine M. Hunt · 2015 · Regulatory Toxicology and Pharmacology
  61. Hepatotoxicity from anabolic androgenic steroids marketed as dietary supplements: contribution from ATP 8B1/ ABCB 11 mutations?
    Y Elsherrif, Jonathan R. Potts, Mark R. Howard, Adrian Barnardo, Stuart R Cairns, Alex S. Knisely, Sumita Verma · 2013 · Liver International
  62. Methylene tetrahydrofolate reductase gene polymorphisms and their association with methotrexate toxicity
    Kalliopi Spyridopoulou, Niki L. Dimou, Stavros J. Hamodrakas, Pantelis G. Bagos · 2011 · Pharmacogenetics and Genomics
  63. The histopathological evaluation of drug‐induced liver injury
    David Erwin Kleiner · 2016 · Histopathology
  64. Post-halothane Jaundice in Relation to Previous Administration of Halothane
    William W. Mushin, M. Rosen, E. V. Jones · 1971 · BMJ
  65. Age-related differences in reporting of drug-associated liver injury: Data-mining of WHO Safety Report Database
    Christine M. Hunt, Nancy Yuen, Heide A. Stirnadel-Farrant, Ayako Suzuki · 2014 · Regulatory Toxicology and Pharmacology
  66. Clinical features and outcomes of patients with drug-induced autoimmune hepatitis: a retrospective cohort study
    Licata, Anna, Maida, Marcello, Cabibi, Daniela, Butera, Giuseppe, Macaluso, Fabio S., Alessi, Nicola, Caruso, Calogero, Craxì, Antonio, Almasio, Piero L. · 2014 · Digestive and Liver Disease
  67. Long‐term follow‐up of patients with mild to moderate drug‐induced liver injury
    Einar Stefan Bjornsson, Evangelos Kalaitzakis, V. AV KLINTEBERG, N. ALEM, Rolf Olsson · 2007 · Alimentary Pharmacology & Therapeutics
  68. Causality Assessment for Suspected DILI During Clinical Phases of Drug Development
    Arie Regev, Leonard B. Seeff, Michael Merz, Sif Ormarsdóttir, Guruprasad Padur Aithal, Jim Gallivan, Paul Brent Watkins · 2014 · Drug Safety
  69. Secondary sclerosing cholangitis in patients with drug-induced liver injury
    Hafsteinn O. Gudnason, Helgi Kristinn Björnsson, Maríanna Garðarsdóttir, Hjalti M. Thorisson, Sigurður Ólafsson, Ottar Mar Bergmann, Einar Stefan Bjornsson · 2015 · Digestive and Liver Disease
  70. Liver pathophysiology
    1995 · Journal of Hepatology
  71. Mann's Pharmacovigilance
    Elizabeth B. Andrews, Nicholas D Moore · 2014 · Wiley eBooks
  72. Characterisation of liver chemistry abnormalities associated with pazopanib monotherapy: A systematic review and meta-analysis of clinical trials in advanced cancer patients
    Thomas B. Powles, Sergio Bracarda A, Mei Chen, Elliot Norry, Natalie Compton, Mark A. Heise, Thomas E. Hutson, Philipp Harter, Christopher L. Carpenter, Lini N. Pandite et al. · 2015 · European Journal of Cancer
  73. Drug-Induced Steatohepatitis Leading to Cirrhosis: Long-Term Toxicity of Amiodarone Use
    Kaiser Raja, Swan N. Thung, Maria Isabel Fiel, Charissa Chang · 2009 · Seminars in Liver Disease
  74. Under-reporting and Poor Adherence to Monitoring Guidelines for Severe Cases of Isoniazid Hepatotoxicity
    Paul Hideyo Hayashi, Robert J. Fontana, Naga Chalasani, Andrew Stolz, Jay A. Talwalkar, Victor J. Navarro, William M. Lee, Timothy J. Davern, David E. Kleiner, Jiezhun Gu et al. · 2015 · Clinical Gastroenterology and Hepatology
  75. The distribution of antinuclear antibody titers in "normal" children and adults.
    Wendy Y. Craig, Thomas B. Ledue, A M Johnson, Robert F. Ritchie · 1999 · PubMed
  76. Case Report: Terbinafine-Induced Prolonged Cholestasis with Reduction of Interlobular Bile Ducts
    Ariane Mallat, Élie Serge Zafrani, Jean‐Michel Métreau, Daniel Dhumeaux · 1997 · Digestive Diseases and Sciences
  77. Rechallenge in drug-induced liver injury: the attractive hazard
    Andrade, Raúl J, Robles, Mercedes, Lucena, María Isabel · 2009 · Expert Opinion on Drug Safety
  78. Assessment of liver fibrosis by transient elastography in rheumatoid arthritis patients treated with methotrexate
    Sung‐Hoon Park, Jung‐Yoon Choe, Seong‐Kyu Kim · 2010 · Joint Bone Spine
  79. Avoiding idiosyncratic DILI: Two is better than one
    Neil Kaplowitz · 2013 · Hepatology
  80. Adverse Events and Treatment Completion for Latent Tuberculosis in Jail Inmates and Homeless Persons
    Mark N. Lobato, Randall R. Reves, Robert M. Jasmer, John C. Grabau, NAOMI N. BOCK, Nong Shang · 2005 · CHEST Journal
  81. Fda arthritis advisory committee meeting
    Harold E. Paulus · 1982 · Arthritis & Rheumatism
  82. Vanishing Bile Duct Syndrome: Amoxicillin‐Clavulanic Acid Associated Intra‐Hepatic Cholestasis Responsive to Ursodeoxycholic Acid
    L Smith, Juan Ignacio, Michele P. Winesett, G Kaiser, Atilano G. Lacson, Enid Gilbert‐Barness, Regino P. González‐Peralta, Michael John Wilsey · 2005 · Journal of Pediatric Gastroenterology and Nutrition
  83. In Vitro Metabolic Activation of Lumiracoxib in Rat and Human Liver Preparations
    Ying Li, J. Greg Slatter, Zhoupeng Zhang, Yan Li, George A. Doss, Matthew P. Braun, Ralph A. Stearns, Dennis C. Dean, Thomas A. Baillie, Wei Tang · 2007 · Drug Metabolism and Disposition
  84. Clinical practice guidelines of the European association for the study of the liver - advancing methodology but preserving practicability
    Cornberg, Markus, Tacke, Frank, Karlsen, Tom H. · 2019 · Journal of Hepatology
  85. Increased risk of hepatotoxicity in HIV-infected pregnant women receiving antiretroviral therapy independent of nevirapine exposure
    David W. Ouyang, David E. Shapiro, Ming Lü, Susan B. Brogly, Audrey L. French, Robert M. Leighty, Bruce Thompson, RUTH E. TUOMALA, Ronald C. Hershow · 2009 · AIDS
  86. Chronic hepatitis B infection and risk of antituberculosis drug-induced liver injury: Systematic review and meta-analysis
    Ning-Tao Wang, Yi‐Shin Huang, Meng-Hsien Lin, Bryan Huang, Chin‐Lin Perng, Han‐Chieh Lin · 2016 · Journal of the Chinese Medical Association
  87. Autoantibodies and Liver Disease: Uses and Abuses
    Zeman, Marilyn V, Hirschfield, Gideon M · 2010 · Canadian Journal of Gastroenterology and Hepatology
  88. Noninvasive monitoring for methotrexate hepatotoxicity
    A. M. MacDonald, Arthur David Burden · 2005 · British Journal of Dermatology
  89. Co-medications That Modulate Liver Injury and Repair Influence Clinical Outcome of Acetaminophen-Associated Liver Injury
    Ayako Suzuki, Nancy Yuen, John S.A. Walsh, Julie I. Papay, Christine M. Hunt, Anna Mae Diehl · 2009 · Clinical Gastroenterology and Hepatology
  90. A Performance Evaluation of Three Drug-Induced Liver Injury Biomarkers in the Rat: Alpha-Glutathione S-Transferase, Arginase 1, and 4-Hydroxyphenyl-Pyruvate Dioxygenase
    Wendy J. Bailey, Dan Holder, Hima Patel, Pam Devlin, Raymond J. Gonzalez, Valerie Hamilton, Nagaraja Muniappa, Diane M. Hamlin, Craig E. Thomas, Frank D. Sistare et al. · 2012 · Toxicological Sciences
  91. Serum microRNA signatures as "liquid biopsies" for interrogating hepatotoxic mechanisms and liver pathogenesis in human
    Julian Krauskopf, Theo M. C. M. de Kok, Shelli Schomaker, Mark M. Gosink, Deborah A. Burt, Patricia A. Chandler, Roscoe L. Warner, Kent J. Johnson, Florian Caiment, Jos C. S. Kleinjans et al. · 2017 · PLoS ONE
  92. Recent advances in biomarkers and therapeutic interventions for hepatic drug safety – false dawn or new horizon?
    Clarke, Joanna I., Dear, James W., Antoine, Daniel J. · 2016 · Expert Opinion on Drug Safety
  93. Immune checkpoint inhibitors: Navigating a new paradigm of treatment toxicities
    Kate Elizabeth Roberts, Vanessa Culleton, Zarnie Lwin, Kenneth John O'Byrne, Brett G.M. Hughes · 2017 · Asia-Pacific Journal of Clinical Oncology
  94. End‐stage methotrexate‐related liver disease is rare and associated with features of the metabolic syndrome
    Muhammad F. Dawwas, Guruprasad Padur Aithal · 2014 · Alimentary Pharmacology & Therapeutics
  95. Drug-Induced Liver Injury in Patients With Preexisting Chronic Liver Disease in Drug Development: How to Identify and Manage?
    Naga Chalasani, Arie Regev · 2016 · Gastroenterology
  96. Ursodeoxycholic acid (UDCA) for the treatment of amoxycillin-clavulanate potassium (Augmentin®)-induced intra-hepatic cholestasis
    Panagiotis Katsinelos, Themistoklis Vasiliadis, Panagiotis Xiarchos, Frida Patakiouta, Kiriakos Christodoulou, Ioannis Pilpilidis, Nikos Eugenidis · 2000 · European Journal of Gastroenterology & Hepatology
  97. Acute liver failure following atorvastatin dose escalation: Is there a threshold dose for idiosyncratic hepatotoxicity?
    Miguel F. Carrascosa, José Ramón Salcines-Caviedes, M. Isabel Lucena, Raúl J. Andrade · 2014 · Journal of Hepatology
  98. Norfloxacin-Induced Eosinophilic Necrotizing Granulomatous Hepatitis
    Einar BjornssonBjörnsson, Rolf Olsson, Helen Elaine Remotti · 2000 · The American Journal of Gastroenterology
  99. Factors That Complicate the Treatment of Tuberculosis in HIV-Infected Patients
    Mark S. Dworkin, Michael R. Adams, David L. Cohn, Arthur J. Davidson, Susan E. Buskin, Carrie Horwitch, Anne Morse, Judy Sackoff, Melanie Thompson, Linda L. Wotring et al. · 2005 · JAIDS Journal of Acquired Immune Deficiency Syndromes
  100. Extrahepatic biliary stenoses after hepatic arterial infusion (HAI) of floxuridine (FUdR) for liver metastases from colorectal cancer.
    Luca Antonio Aldrighetti, Marcella Arru, Monica Ronzoni, Maria Teresa Salvioni, Eugenio Villa, Gianfranco Ferla · 2001 · PubMed
  101. Ketamine-Induced Cholangiopathy: A Case Report
    Wai‐Kay Seto, MATTHEW MA‐TAI NG, Pierre Chan, Irene Oi‐Lin Ng, Stephen Chi-Wai Cheung, Ivan Fan‐Ngai Hung, Man‐Fung Yuen, Ching‐Lung Lai · 2011 · The American Journal of Gastroenterology
  102. 63 Years and 715 Days to the “Boxed Warning”: Unmasking of the Propylthiouracil Problem
    Scott A. Rivkees · 2010 · International Journal of Pediatric Endocrinology
  103. Flucloxacillin induced liver disease: histopathological findings at biopsy and autopsy
    Robert P. Eckstein, John F. Dowsett, Michael R. Lunzer · 1993 · Pathology
  104. Are Polymorphisms in Genes Relevant to Drug Disposition Predictors of Susceptibility to Drug-Induced Liver Injury?
    Ann K. Daly · 2016 · Pharmaceutical Research
  105. Test systems in drug discovery for hazard identification and risk assessment of human drug-induced liver injury
    Richard John Weaver, Catherine Jean Betts, Eric A.G. Blomme, Helga H.J. Gerets, Klaus Gjervig Jensen, Philip G. Hewitt, Satu Juhila, Gilles Labbe, Michael J. Liguori, Natalie Mesens et al. · 2017 · Expert Opinion on Drug Metabolism & Toxicology
  106. The Characteristics and Clinical Outcome of Drug-induced Liver Injury
    Ramazan Idılman, Mehmet Selçuk Bektaş, Kubilay Cnar, Murat Törüner, Ethem Turgay Cerit, Beyza Doğanay Erdoğan, Esra Erden, Hakan Bozkaya, Kadir Bahar, Selim Karayalçın et al. · 2010 · Journal of Clinical Gastroenterology
  107. Evidence for a potential protective effect of carnitine-pantothenic acid co-treatment on valproic acid-induced hepatotoxicity
    Dana Felker, Alexandra Lynn, Sue Wang, Dale E. Johnson · 2014 · Expert Review of Clinical Pharmacology
  108. Steroid Therapy for a Case of Severe Drug-Induced Cholestasis
    Antonietta Giannattasio, Mariangela D’Ambrosi, Monica Volpicelli, Raffaele Federico Iorio · 2006 · Annals of Pharmacotherapy
  109. Hepatic Damage by Natural Remedies
    Medina-Caliz, Inmaculada, Gonzalez-Jimenez, Andres, Garcia-Cortes, Miren, Lucena, M. Isabel, Andrade, Raul · 2018 · Seminars in Liver Disease
  110. The heterozygous Sod2 mouse: modeling the mitochondrial role in drug toxicity
    Urs Alex Boelsterli, Chin-Ju J. Hsiao · 2008 · Drug Discovery Today
  111. Antituberculosis drug-induced liver injury in chronic hepatitis and cirrhosis
    Wan Beom Park, Won Kyum Kim, Kook Lae Lee, Jae‐Joon Yim, Moonsuk Kim, Yong Jin Jung, Nam Joong Kim, Donghee Kim, Yoon Jun Kim, Jung‐Hwan Yoon et al. · 2010 · Journal of Infection
  112. Acute Liver Failure due to Enalapril
    Michael Jeserich, Christian H. Ihling, Hans-Peter Allgaier, Peter Alfred Berg, Claus Heilmann · 2000 · Herz
  113. Liver cirrhosis induced by long-term administration of a daily low dose of amiodarone: A case report
    Hiroki Oikawa · 2005 · World Journal of Gastroenterology
  114. Methimazole-induced cholestatic liver injury, mimicking sclerosing cholangitis
    Gerhard P. Schwab, Gerold J. Wetscher, W. Vogl, Elizabeth J. Redmond · 1996 · Langenbeck s Archives of Surgery
  115. Hepatotoxicity of alpha-methyldopa in pregnancy
    R. Slim, Chaker Ben Salem, Houssem Hmouda, Kamel Bouraoui · 2010 · Journal of Clinical Pharmacy and Therapeutics
  116. The Pharmacogenomic HLA Biomarker Associated to Adverse Abacavir Reactions: Comparative Analysis of Different Genotyping Methods
    Laura Stocchi, Raffaella Cascella, Stefania Zampatti, Antonella Pirazzoli, Giuseppe Novelli, Emiliano Giardina · 2012 · Current Genomics
  117. Nitrofurantoin-induced lung- and hepatotoxicity
    Anastasios Koulaouzidis, Shivaram K. Bhat, John M Moschos, Chew Tan, Ana De Ramon · 2007 · Annals of Hepatology
  118. Diagnosis, presentation and initial severity of Autoimmune Hepatitis ( AIH ) in patients attending 28 hospitals in the UK
    Victoria Gordon, Ratul Adhikary, Victoria J. Appleby, Debasish Das, James W Day, Toby Delahooke, Selena Dixon, David A. Elphick, Claire Madeline Hardie, Barbara Hoeroldt et al. · 2018 · Liver International
  119. Relationship Between Characteristics of Medications and Drug-Induced Liver Disease Phenotype and Outcome
    Raj Vuppalanchi, Raghavender Gotur, K. Rajender Reddy, Robert J. Fontana, Marwan Ghabril, Andrzej Stanislaw Kosinski, Jiezhun Gu, José Serrano, Naga Chalasani · 2013 · Clinical Gastroenterology and Hepatology
  120. A prospective study on the causes of notably raised alanine aminotransferase (ALT)
    Helgi Kristinn Björnsson, Sigurður Ólafsson, Ottar Mar Bergmann, Einar Stefan Bjornsson · 2015 · Scandinavian Journal of Gastroenterology
  121. Drug-Induced Liver Disease
    Hatton W. Sumner, Jordan L. Holtzman, Craig James McClain · 2013 · Elsevier eBooks
  122. Heavy Consumption of Alcohol is Not Associated With Worse Outcomes in Patients With Idiosyncratic Drug-induced Liver Injury Compared to Non-Drinkers
    Dakhoul, Lara, Ghabril, Marwan, Gu, Jiezhun, Navarro, Victor, Chalasani, Naga, Serrano, Jose · 2018 · Clinical Gastroenterology and Hepatology
  123. The binomial distribution
    Pierre Jolicoeur · 1999 · Springer eBooks
  124. Liver Safety Assessment in Special Populations (Hepatitis B, C, and Oncology Trials)
    Gerd Achim Kullak-Ublick, Michael Merz, Louis H. Griffel, Neil Kaplowitz, Paul Brent Watkins · 2014 · Drug Safety
  125. Bile duct complications of hepatic arterial infusion chemotherapy evaluated by helical CT
    Sith Phongkitkarun, Satoshi Kobayashi, Vithya Varavithya, Xuelin Huang, Steven A. Curley, Chuslip Charnsangavej · 2005 · Clinical Radiology
  126. Reye's syndrome-like illness in a patient receiving amiodarone.
    D B Jones, Florabel G. Mullick, Jay H. Hoofnagle, Bruce G Baranski · 1988 · PubMed
  127. Sclerosing Cholangitis from Intraarterial Floxuridine
    Asim Dikengil, Barry N. Siskind, Steven S. Morse, Anne P. Swedlund, Kathleen E. Bober-Sorcinelli, Morton I. Burrell, Alexander R. Margulis · 1986 · Journal of Clinical Gastroenterology
  128. Thioguanin-induced nodular regenerative hyperplasia of the liver-ROC analysis of different MR techniques
    Christoph Johannes Zech, Julia Seiderer, Walter Reinisch, Thomas Ochsenkühn, Wolfgang Schima, Joachim Diebold, Fritz Wrba, Maximilian Ferdinand Reiser, Stefan Oswald Schoenberg · 2007 · European Radiology
  129. Clinical characteristics and prognostic indicators of drug-induced fulminant hepatic failure.
    Shigeru Ohmori, Katsuya Shiraki, Hidekazu Inoue, Hiroshi Okano, Takenari Yamanaka, Masatoshi Deguchi, Takahisa Sakai, Koujiro Takase, Takeshi Nakano, Yukihiko Tameda · 2003 · PubMed
  130. Tetracycline-associated fatty liver in the male
    Morton J. Robinson, Arkadi M. Rywlin · 1970 · Digestive Diseases and Sciences
  131. Severe propylthiouracil-induced hepatotoxicity in pregnancy managed successfully by liver transplantation: A case report
    Evan Sequeira, Sikolia Wanyonyi, Raj Dodia · 2011 · Journal of Medical Case Reports
  132. N‐acetylcysteine and prednisolone treatment improved serum biochemistries in suspected flupirtine cases of severe idiosyncratic liver injury
    Jürgen T. Borlak, Florian van Bömmel, Thomas Berg · 2017 · Liver International
  133. Mechanisms Underlying the Hepatotoxicity of Nonsteroidal Antiinflammatory Drugs
    Urs Alex Boelsterli · 2013 · Elsevier eBooks
  134. Elevation of Liver Enzymes in Multiple Dose Trials During Placebo Treatment: Are They Predictable?
    Michael Merz, Michael Seiberling, GUNTER HOXTER, M. Hölting, H. Wortha · 1997 · The Journal of Clinical Pharmacology
  135. A case of drug‐induced ductopenia resulting in fatal biliary cirrhosis
    Motoyasu Ishii, Yutaka Miyazaki, Takeshi Yamamoto, Masahito Miura, Yoshiyuki Ueno, Tohru Takahashi, Takayoshi Toyota · 1993 · Liver International
  136. Docetaxel Induced Sclerosing Cholangitis
    Jennifer L. Horsley‐Silva, Elizabeth N. Dow, Christine O. Menias, Maxwell Lawrence Smith, Estrella M. Carballido, Keith D. Lindor, Hugo E. Vargas · 2015 · Digestive Diseases and Sciences
  137. Ursodeoxycholic acid for the treatment of fluchoxacillin-associated cholestasis
    Andrzej Piotrowicz, Michael Iain Polkey, Mark Wilkinson · 1995 · Journal of Hepatology
  138. Dangerous liaisons: Drug, host and the environment
    Guruprasad Padur Aithal · 2007 · Journal of Hepatology
  139. Overview of Mechanisms of Drug-Induced Liver Injury (DILI) and Key Challenges in DILI Research
    Nabil Noureddin, Neil Kaplowitz · 2018 · Methods in pharmacology and toxicology
  140. Rapid progression to liver cirrhosis of toxic hepatitis due to ebrotidine
    Juan Antonio Pineda, Juan Larraui, Juan Macı́as, Angel Hernández, Javier Guijarro, Manuel Sayago, Francisco Gavilán, José Aguilar, Eduardo Lissen · 1999 · Journal of Hepatology
  141. Genome-Wide Association Studies in Drug-Induced Liver Injury: Step Change in Understanding the Pathogenesis
    Jane I. Grove, Guruprasad Padur Aithal · 2015 · Seminars in Liver Disease
  142. The placebo effect in healthy volunteers: influence of experimental conditions on physiological parameters during phase I studies.
    Pierre Rosenzweig, S. Brohier, Andreas Zipfel · 1995 · British Journal of Clinical Pharmacology
  143. Laboratory data in healthy volunteers: reference values, reference changes, screening and laboratory adverse event limits in Phase I clinical trials
    Michel Sibille, N. Deigat, I. Durieu, M. Guillaumont, D. Morel, Jacques Bienvenu, Denis Massignon, D. Vital Durand · 1999 · European Journal of Clinical Pharmacology
  144. High Prevalence of Ibuprofen Drug-Induced Liver Injury in Spanish and Latin-American Registries
    Miguel Eugenio Zoubek, Andres Gonzalez-Jimenez, Inmaculada Medina‐Cáliz, Mercedes Robles‐Díaz, Nelia Hernández, Manuel Romero‐Gómez, Fernando Bessone, Hacibe Hallal, Francisco Javier Cubero, M. Isabel Lucena et al. · 2017 · Clinical Gastroenterology and Hepatology
  145. FDA arthritis advisory committee meeting
    Harold E. Paulus · 1982 · Arthritis & Rheumatism
  146. Human Leukocyte Antigen (HLA) Pharmacogenomic Tests: Potential and Pitfalls
    Ann K. Daly · 2014 · Current Drug Metabolism
  147. Drug-Induced Liver Injury: Icelandic Lessons
    Jay H. Hoofnagle, Victor J. Navarro · 2013 · Gastroenterology
  148. Direct-Acting Antivirals for Chronic Hepatitis C: Can Drug Properties Signal Potential for Liver Injury?
    Poonam Mishra, Minjun Chen · 2017 · Gastroenterology
  149. Hcv coinfection, an important risk factor for hepatotoxicity in pregnant women starting antiretroviral therapy
    Ingrid J.M. Snijdewind, Colette Smit, Mieke H. Godfried, Jeannine F. Nellen, Frank de Wolf, Kees Boer, Marchina E. van der Ende · 2011 · Journal of Infection
  150. Hepatotoxicity Related to Methotrexate
    Guruprasad Padur Aithal · 2013 · Elsevier eBooks
  151. Coding variants in PNPLA3 and TM6SF2 are risk factors for hepatic steatosis and elevated serum alanine aminotransferases caused by a glucagon receptor antagonist
    Cristina B. Guzmán, Suman Duvvuru, Patrick Anthony Akkari, Pallav Bhatnagar, Chakib Battioui, Wendra M. Foster, Xiaotian Michelle Zhang, Sudha S. Shankar, Mark A. Deeg, Naga Chalasani et al. · 2018 · Hepatology Communications
  152. Preliminary Results of a Novel Algorithmic Method Aiming to Support Initial Causality Assessment of Routine Pharmacovigilance Case Reports for Medication-Induced Liver Injury: The PV-RUCAM
    Scalfaro, Erik, Streefkerk, Henk Johan, Merz, Michael, Meier, Christoph, Lewis, David · 2017 · Drug Safety
  153. Hepatotoxicity of Antitubercular Drugs
    Sumita Verma, Neil Kaplowitz · 2013 · Elsevier eBooks
  154. Extreme hyperbilirubinemia associated with the use of anabolic steroids, health/nutritional supplements, and ethanol: response to ursodeoxycholic acid treatment.
    C Singh, P Bishop, R Willson · 1996 · PubMed
  155. Análisis de las causas, características y consecuencias de la reexposición al fármaco o compuesto responsable de un episodio de hepatotoxicidad
    Alejandra Fernández Castañer, Miren García‐Cortés, M. Isabel Lucena, Yolanda Borraz, Gloria Isabel Carvajal Peláez, J. Costa, Sandra Anzola, J F Martínez Salmerón, Sandra Patricia Grijalva Ávila, José Antonio Durán et al. · 2008 · Revista Española de Enfermedades Digestivas
  156. Can rechallenge be done safely after mild or moderate drug‐induced liver injury?
    John R. Senior · 2015 · Hepatology
  157. Adverse Events and Treatment Completion for Latent Tuberculosis in Jail Inmates and Homeless Persons
    Lynn T. Tanoue · 2006 · Yearbook of Pulmonary Disease
  158. Hepatocellular adenoma with malignant transformation in a patient with neonatal portal vein thrombosis
    Lionel Arrivé, Jessica Zucman‐Rossi, Pierre Balladur, Dominique Wendum · 2016 · Hepatology
  159. Immune-Mediated Drug-Induced Liver Injury
    Einar Stefan Bjornsson, Guruprasad Padur Aithal · 2013 · Springer eBooks
  160. Hydralazine-induced hepatitis in pregnancy.
    Moshe Hod, S.A. Friedman, A Schoenfeld, E Theodor, Jordanka I. Ovadia · 1986 · PubMed
  161. Hepatic Adverse Drug Reactions
    Guruprasad Padur Aithal, Dominique G. Larrey · 2014 · Wiley eBooks
  162. Pathogenesis of Idiosyncratic Drug Induced Liver Injury
    Lily Dara, Z.-X. Liu, Neil Kaplowitz · 2017 · Elsevier eBooks
  163. Evidence-Based Liver Chemistry Monitoring in Drug Development
    Christine M. Hunt, John K. Forster, Julie I. Papay, Heide A. Stirnadel-Farrant · 2009 · Pharmaceutical Medicine
  164. Data on placebo in healthy volunteers: impact of experimental conditions on safety, and on laboratory and physiological variables during phase I trials.
    Pierre Rosenzweig, S. Brohier, Andreas Zipfel · 1996 · PubMed
  165. Interpretation, Integration, and Implementation of In Vitro Assay Data: The Predictive Toxicity Challenge
    Deborah S. Light, Michael D. Aleo, J. Gerry Kenna · 2018 · Methods in pharmacology and toxicology
  166. Successful Use of Ursodeoxycholic Acid in Nodular Regenerative Hyperplasia of the Liver
    Giusy Ranucci, Francesco Cirillo, Claudia Della Corte, Raffaella Vecchione, Gianfranco Vallone, Raffaele Federico Iorio · 2011 · Annals of Pharmacotherapy