Near-infrared fluorescent Aza-BODIPY dyes: Rational structural design and biomedical imaging

Aggregation-Induced Emission: Together We Shine, United We Soar!

Mei, J., Leung, N. L. C., Kwok, R. T. K., Lam, J. W. Y., & Tang, B. Z. (2015) · Chemical Reviews · doi:10.1021/acs.chemrev.5b00263 · Cited by 8,270 · see citing works

BODIPY Dyes and Their Derivatives:  Syntheses and Spectroscopic Properties

Loudet, A., & Burgess, K. (2007) · Chemical Reviews · doi:10.1021/cr078381n · Cited by 5,238 · see citing works

A phase 3 trial of pirfenidone in patients with idiopathic pulmonary fibrosis.

King, T. E., Bradford, W. Z., Castro-Bernardini, S., Fagan, E. A., Glaspole, I., Glassberg, M. K., Gorina, E., Hopkins, P. M., Kardatzke, D., Lancaster, L., et al. (2014) · New England Journal of Medicine · doi:10.1056/nejmoa1402582 · Cited by 3,975 · see citing works

Aggregation‐Induced Emission: The Whole Is More Brilliant than the Parts

Mei, J., Hong, Y., Lam, J. W. Y., Qin, A., Tang, Y., & Tang, B. Z. (2014) · Advanced Materials · doi:10.1002/adma.201401356 · Cited by 3,385 · see citing works

Near-infrared fluorophores for biomedical imaging

Hong, G., Antaris, A. L., & Dai, H. (2017) · Nature Biomedical Engineering · doi:10.1038/s41551-016-0010 · Cited by 3,013 · see citing works

J‐Aggregates: From Serendipitous Discovery to Supramolecular Engineering of Functional Dye Materials

Würthner, F., Kaiser, T. E., & Saha‐Möller, C. R. (2011) · Angewandte Chemie International Edition · doi:10.1002/anie.201002307 · Cited by 2,597 · see citing works

Signals from the lysosome: a control centre for cellular clearance and energy metabolism

Settembre, C., Fraldi, A., Medina, D. L., & Ballabio, A. (2013) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm3565 · Cited by 1,689 · see citing works

Drug-induced hepatotoxicity

Lee, W. M. (2003) · New England Journal of Medicine · doi:10.1056/nejmra021844 · Cited by 1,594 · see citing works

Structural modification strategies for the rational design of red/NIR region BODIPYs

Lü, H., Mack, J. P., Yang, Y., & Shen, Z. (2014) · Chemical Society Reviews · doi:10.1039/c4cs00030g · Cited by 1,332 · see citing works

First-in-human liver-tumour surgery guided by multispectral fluorescence imaging in the visible and near-infrared-I/II windows

Hu, Z., Fang, C., Li, B., Zhang, Z., Cao, C., Cai, M., Su, S., Sun, X., Shi, X., Li, C., et al. (2019) · Nature Biomedical Engineering · doi:10.1038/s41551-019-0494-0 · Cited by 1,126 · see citing works

Fluorescent Probes for Sensing and Imaging within Specific Cellular Organelles

Zhu, H., Fan, J., Du, J., & Peng, X. (2016) · Accounts of Chemical Research · doi:10.1021/acs.accounts.6b00292 · Cited by 987 · see citing works

A Mechanically Strong, Highly Stable, Thermoplastic, and Self‐Healable Supramolecular Polymer Hydrogel

Dai, X., Zhang, Y., Gao, L., Bai, T., Wang, W., Cui, Y., & Liu, W. (2015) · Advanced Materials · doi:10.1002/adma.201500534 · Cited by 848 · see citing works

Light in diagnosis, therapy and surgery

Yun, S. H., & Kwok, S. J. J. (2017) · Nature Biomedical Engineering · doi:10.1038/s41551-016-0008 · Cited by 806 · see citing works

Obesity, Inflammation, and Cancer

Deng, T., Lyon, C. J., Bergin, S. M., Caligiuri, M. A., & Hsueh, W. A. (2016) · Annual Review of Pathology Mechanisms of Disease · doi:10.1146/annurev-pathol-012615-044359 · Cited by 801 · see citing works

Restriction of Intramolecular Motions: The General Mechanism behind Aggregation‐Induced Emission

Leung, N. L. C., Xie, N., Yuan, W. Z., Liu, Y., Wu, Q., Peng, Q., Miao, Q., Lam, J. W. Y., & Tang, B. Z. (2014) · Chemistry - A European Journal · doi:10.1002/chem.201403811 · Cited by 799 · see citing works

The lysosome: from waste bag to potential therapeutic target

Appelqvist, H., Wäster, P., Kågedal, K., & Öllinger, K. (2013) · Journal of Molecular Cell Biology · doi:10.1093/jmcb/mjt022 · Cited by 772 · see citing works

Molecular Engineering of NIR‐II Fluorophores for Improved Biomedical Detection

Lei, Z., & Zhang, F. (2020) · Angewandte Chemie International Edition · doi:10.1002/anie.202007040 · Cited by 689 · see citing works

<i>J</i> -Aggregates of Cyanine Dye for NIR-II <i>in Vivo</i> Dynamic Vascular Imaging beyond 1500 nm

Sun, C., Li, B., Zhao, M., Wang, S., Lei, Z., Lu, L., Zhang, H., Feng, L., Dou, C., Yin, D., et al. (2019) · Journal of the American Chemical Society · doi:10.1021/jacs.9b10043 · Cited by 582 · see citing works

Near-infrared luminescence high-contrast in vivo biomedical imaging

Chen, Y., Wang, S., & Zhang, F. (2023) · Nature Reviews Bioengineering · doi:10.1038/s44222-022-00002-8 · Cited by 582 · see citing works

Fluorescence imaging of pathophysiological microenvironments

Wang, S., Ren, W. X., Hou, J.-T., Won, M., An, J., Chen, X., Shu, J., & Kim, J. S. (2021) · Chemical Society Reviews · doi:10.1039/d1cs00083g · Cited by 568 · see citing works

Bioapplications of small molecule Aza-BODIPY: from rational structural design to in vivo investigations

Shi, Z., Xu, H., Hu, W., Bai, H., Peng, B., Ji, L., Fan, Q., Li, L., & Huang, W. (2020) · Chemical Society Reviews · doi:10.1039/d0cs00234h · Cited by 474 · see citing works

Paradigms of acute kidney injury in the intensive care setting

Kellum, J. A., & Prowle, J. R. (2018) · Nature Reviews Nephrology · doi:10.1038/nrneph.2017.184 · Cited by 420 · see citing works

Synthesis of BF 2 chelates of tetraarylazadipyrromethenes and evidence for their photodynamic therapeutic behaviour

KILLORAN, J. J., Allen, L. T., Gallagher, J. F., Gallagher, W. M., & O’Shea, D. F. (2002) · Chemical Communications · doi:10.1039/b204317c · Cited by 408 · see citing works

Serum alanine aminotransferase in skeletal muscle diseases†

Nathwani, R. A., Pais, S. A., Reynolds, T. B., & Kaplowitz, N. (2005) · Hepatology · doi:10.1002/hep.20548 · Cited by 400 · see citing works

Biomedical Micro‐/Nanomotors: From Overcoming Biological Barriers to In Vivo Imaging

Gao, C., Wang, Y., Ye, Z., Lin, Z., Ma, X., & He, Q. Z. (2020) · Advanced Materials · doi:10.1002/adma.202000512 · Cited by 362 · see citing works

Azadipyrromethenes: from traditional dye chemistry to leading edge applications

Ge, Y., & O’Shea, D. F. (2016) · Chemical Society Reviews · doi:10.1039/c6cs00200e · Cited by 355 · see citing works

Type I photodynamic therapy by organic–inorganic hybrid materials: From strategies to applications

Wang, Y., Liu, Y., Sun, H., & Guo, D. (2019) · Coordination Chemistry Reviews · doi:10.1016/j.ccr.2019.05.016 · Cited by 344 · see citing works

Applications of bioluminescence in biotechnology and beyond

Syed, A. J., & Anderson, J. C. (2021) · Chemical Society Reviews · doi:10.1039/d0cs01492c · Cited by 344 · see citing works

Long-term outcomes of acute kidney injury and strategies for improved care

James, M. T., Bhatt, M., Pannu, N., & Tonelli, M. A. (2020) · Nature Reviews Nephrology · doi:10.1038/s41581-019-0247-z · Cited by 315 · see citing works

Conformationally Restricted Aza‐Bodipy: A Highly Fluorescent, Stable, Near‐Infrared‐Absorbing Dye

Zhao, W., & Carreira, E. M. (2005) · Angewandte Chemie International Edition · doi:10.1002/anie.200461868 · Cited by 301 · see citing works

J-aggregates of meso-[2.2]paracyclophanyl-BODIPY dye for NIR-II imaging

Li, K., Duan, X., Jiang, Z., Ding, D., Chen, Y., Zhang, G.-Q., & Liu, Z. (2021) · Nature Communications · doi:10.1038/s41467-021-22686-z · Cited by 301 · see citing works

Conformationally Restricted Aza‐BODIPY: Highly Fluorescent, Stable Near‐Infrared Absorbing Dyes

Zhao, W., & Carreira, E. M. (2006) · Chemistry - A European Journal · doi:10.1002/chem.200600527 · Cited by 291 · see citing works

Supramolecularly Engineered J-Aggregates Based on Perylene Bisimide Dyes

Hecht, M., & Würthner, F. (2020) · Accounts of Chemical Research · doi:10.1021/acs.accounts.0c00590 · Cited by 288 · see citing works

Ablation of the Inflammatory Enzyme Myeloperoxidase Mitigates Features of Parkinson's Disease in Mice

Choi, D., Pennathur, S., Perier, C., Tieu, K., Teismann, P., Wu, D.-C., Jackson-Lewis, V. R., Vila, M., Vonsattel, J., Heinecke, J. W., et al. (2005) · Journal of Neuroscience · doi:10.1523/jneurosci.0970-05.2005 · Cited by 284 · see citing works

Rational Design of Nanocarriers for Intracellular Protein Delivery

Qin, X., Yu, C., Wei, J., Li, L., Zhang, C., Wu, Q., Liu, J., Yao, S. Q., & Huang, W. (2019) · Advanced Materials · doi:10.1002/adma.201902791 · Cited by 281 · see citing works

Activatable Photoacoustic Nanoprobes for In Vivo Ratiometric Imaging of Peroxynitrite

Zhang, J., Xu, Z. J., Upputuri, P. K., Pramanik, M., Chen, P., & Pu, K. (2016) · Advanced Materials · doi:10.1002/adma.201604764 · Cited by 272 · see citing works

A timeline of hydrogen sulfide (H2S) research: From environmental toxin to biological mediator

Szabó, C. (2017) · Biochemical Pharmacology · doi:10.1016/j.bcp.2017.09.010 · Cited by 271 · see citing works

In vivo fluorescence imaging: success in preclinical imaging paves the way for clinical applications

Refaat, A., Yap, M. L., Pietersz, G. A., Walsh, A. P. G., Zeller, J., del Rosal, B., Wang, X., & Peter, K. (2022) · Journal of Nanobiotechnology · doi:10.1186/s12951-022-01648-7 · Cited by 269 · see citing works

Molecular Fluorophores for Deep-Tissue Bioimaging

Wang, S., Li, B., & Zhang, F. (2020) · ACS Central Science · doi:10.1021/acscentsci.0c00544 · Cited by 268 · see citing works

BODIPY as a Multifunctional Theranostic Reagent in Biomedicine: Self‐Assembly, Properties, and Applications

Cheng, H., Cao, X., Zhang, S., Zhang, K., Cheng, Y., Wang, J., Zhao, J., Zhou, L., Liang, X., & Yoon, J. (2022) · Advanced Materials · doi:10.1002/adma.202207546 · Cited by 264 · see citing works

Ultrabright gap-enhanced Raman tags for high-speed bioimaging

Zhang, Y., Gu, Y., He, J. J., Thackray, B. D., & Ye, J. (2019) · Nature Communications · doi:10.1038/s41467-019-11829-y · Cited by 259 · see citing works

Chlorophyll J-Aggregates: From Bioinspired Dye Stacks to Nanotubes, Liquid Crystals, and Biosupramolecular Electronics

Sengupta, S., & Würthner, F. (2013) · Accounts of Chemical Research · doi:10.1021/ar400017u · Cited by 243 · see citing works

Recent developments in multimodality fluorescence imaging probes

Zhao, J., Chen, J., Ma, S., Liu, Q., Huang, L., Chen, X., Lou, K., & Wang, W. (2018) · Acta Pharmaceutica Sinica B · doi:10.1016/j.apsb.2018.03.010 · Cited by 243 · see citing works

Syntheses of Highly Fluorescent GFP-Chromophore Analogues

Wu, L., & Burgess, K. (2008) · Journal of the American Chemical Society · doi:10.1021/ja710388h · Cited by 230 · see citing works

Consequences of Copper Accumulation in the Livers of the Atp7b−/− (Wilson Disease Gene) Knockout Mice

Hüster, D., Finegold, M. J., Morgan, C. T., Burkhead, J. L., Nixon, R. R., Vanderwerf, S. M., Gilliam, T. C., & Lutsenko, S. (2006) · American Journal Of Pathology · doi:10.2353/ajpath.2006.050312 · Cited by 223 · see citing works

3D NIR‐II Molecular Imaging Distinguishes Targeted Organs with High‐Performance NIR‐II Bioconjugates

Zhu, S., Herraiz, S., Yue, J., Zhang, M., Wan, H., Yang, Q., Ma, Z., Wang, Y., He, J. H., Antaris, A. L., et al. (2018) · Advanced Materials · doi:10.1002/adma.201705799 · Cited by 215 · see citing works

Near‐IR Absorbing J‐Aggregate of an Amphiphilic BF ₂ ‐Azadipyrromethene Dye by Kinetic Cooperative Self‐Assembly

Chen, Z., Liu, Y., Wagner, W., Stepanenko, V., Ren, X., Ogi, S., & Würthner, F. (2017) · Angewandte Chemie International Edition · doi:10.1002/anie.201701788 · Cited by 212 · see citing works

Lysosomal Function and Dysfunction: Mechanism and Disease

Boya, P. (2011) · Antioxidants and Redox Signaling · doi:10.1089/ars.2011.4405 · Cited by 211 · see citing works

A Ratiometric Acoustogenic Probe for in Vivo Imaging of Endogenous Nitric Oxide

Reinhardt, C. J., Zhou, E. Y., Jorgensen, M. D., Partipilo, G., & Chan, J. (2018) · Journal of the American Chemical Society · doi:10.1021/jacs.7b10783 · Cited by 210 · see citing works

Near-Infrared Sensing Properties of Dimethlyamino-Substituted BF 2 −Azadipyrromethenes

McDonnell, S. O., & O’Shea, D. F. (2006) · Organic Letters · doi:10.1021/ol061171x · Cited by 201 · see citing works

Visualization of ONOO– and Viscosity in Drug-Induced Hepatotoxicity with Different Fluorescence Signals by a Sensitive Fluorescent Probe

Deng, Y., & Feng, G. (2020) · Analytical Chemistry · doi:10.1021/acs.analchem.0c03199 · Cited by 201 · see citing works

pH-Triggered and Enhanced Simultaneous Photodynamic and Photothermal Therapy Guided by Photoacoustic and Photothermal Imaging

Tang, Q., Xiao, W., Huang, C., Si, W., Shao, J., Huang, W., Chen, P., Zhang, Q., & Dong, X. (2017) · Chemistry of Materials · doi:10.1021/acs.chemmater.7b01075 · Cited by 197 · see citing works

Rational Design of Conjugated Photosensitizers with Controllable Photoconversion for Dually Cooperative Phototherapy

Ye, S., Rao, J., Qiu, S., Zhao, J., He, H., Yan, Z., Yang, T., Deng, Y., Ke, H., Yang, H., et al. (2018) · Advanced Materials · doi:10.1002/adma.201801216 · Cited by 194 · see citing works

Enforcing Extended Porphyrin J-Aggregate Stacking in Covalent Organic Frameworks

Keller, N., Calik, M., Sharapa, D. I., Soni, H. R., Zehetmaier, P. M., Rager, S., Auras, F., Jakowetz, A. C., Görling, A., Clark, T., et al. (2018) · Journal of the American Chemical Society · doi:10.1021/jacs.8b08088 · Cited by 192 · see citing works

Water-Soluble BODIPY Photocages with Tunable Cellular Localization

Kand, D., Liu, P., Navarro, M. X., Fischer, L. J., Rousso-Noori, L., Friedmann‐Morvinski, D., Winter, A. H., Miller, E. W., & Weinstain, R. (2020) · Journal of the American Chemical Society · doi:10.1021/jacs.9b13219 · Cited by 191 · see citing works

Novel aza-BODIPY based small molecular NIR-II fluorophores for <i>in vivo</i> imaging

Bai, L., Sun, P., Liu, Y., Zhang, H., Hu, W., Zhang, W., Liu, Z., Fan, Q., Li, L., & Huang, W. (2019) · Chemical Communications · doi:10.1039/c9cc03378e · Cited by 187 · see citing works

Observation of the Generation of ONOO– in Mitochondria under Various Stimuli with a Sensitive Fluorescence Probe

Li, H., Li, X., Wu, X., Shi, W. S., & Ma, H. (2017) · Analytical Chemistry · doi:10.1021/acs.analchem.7b00503 · Cited by 181 · see citing works

Clinical Value of Fluorine-18 2-Fluoro-2-Deoxy-D-Glucose Positron Emission Tomography/Computed Tomography in Bladder Cancer

Apolo, A. B., Riches, J. C., Schöder, H. M., Akın, O., Trout, A., Milowsky, M. I., & Bajorin, D. F. (2010) · Journal of Clinical Oncology · doi:10.1200/jco.2010.28.7052 · Cited by 179 · see citing works

B , O -Chelated Azadipyrromethenes as Near-IR Probes

Loudet, A., Bandichhor, R., Burgess, K., Palma, A., McDonnell, S. O., Hall, M. J., & O’Shea, D. F. (2008) · Organic Letters · doi:10.1021/ol8018506 · Cited by 177 · see citing works

Aza-BODIPY-Based Nanomedicines in Cancer Phototheranostics

Chen, D., Zhong, Z., Ma, Q., Shao, J., Huang, W., & Dong, X. (2020) · ACS Applied Materials & Interfaces · doi:10.1021/acsami.0c05021 · Cited by 172 · see citing works

Anti-Inflammatory and Cytoprotective Actions of Hydrogen Sulfide: Translation to Therapeutics

Wallace, J. L., Blackler, R. W., Chan, M. V., Da Silva, G. J., Elsheikh, W., Flannigan, K. L., Gamaniek, I., Manko, A., Wang, L., Motta, J.-P., et al. (2015) · Antioxidants &amp; Redox Signaling · doi:10.1089/ars.2014.5901 · Cited by 156 · see citing works

Randomized, double-blind comparison of indocyanine green with or without albumin premixing for near-infrared fluorescence imaging of sentinel lymph nodes in breast cancer patients

Hutteman, M., Mieog, J. S. D., van der Vorst, J. R., Liefers, G., Putter, H., Löwik, C. W. G. M., Frangioni, J. V., van de Velde, C. J. H., & Vahrmeijer, A. L. (2011) · Breast Cancer Research and Treatment · doi:10.1007/s10549-011-1419-0 · Cited by 155 · see citing works

Oncologic Procedures Amenable to Fluorescence-guided Surgery

Tipirneni, K. E., Warram, J. M., Moore, L. S., Prince, A. C., de Boer, E., Jani, A. H., Wapnir, I., Liao, J. C., Bouvet, M., Behnke, N. K., et al. (2016) · Annals of Surgery · doi:10.1097/sla.0000000000002127 · Cited by 155 · see citing works

Sustainable Nanosheet Antioxidants for Sepsis Therapy via Scavenging Intracellular Reactive Oxygen and Nitrogen Species

Yim, D., Lee, D., So, Y., Choi, C., Son, W., Jang, K., Yang, C., & Kim, J. (2020) · ACS Nano · doi:10.1021/acsnano.0c03807 · Cited by 155 · see citing works

A Versatile Theranostic Nanoemulsion for Architecture‐Dependent Multimodal Imaging and Dually Augmented Photodynamic Therapy

Zhang, Y., Bo, S., Feng, T., Qin, X., Wan, Y., Jiang, S., Li, C., Lin, J., Wang, T., Zhou, X. H., et al. (2019) · Advanced Materials · doi:10.1002/adma.201806444 · Cited by 153 · see citing works

Stable J‐Aggregation of an aza‐BODIPY‐Lipid in a Liposome for Optical Cancer Imaging

Cheng, M. H. Y., Harmatys, K. M., Charron, D. M., Chen, J., & Zheng, G. (2019) · Angewandte Chemie International Edition · doi:10.1002/anie.201907754 · Cited by 145 · see citing works

Trends in traumatic brain injury mortality in China, 2006–2013: A population-based longitudinal study

Cheng, P., Yin, P., Ning, P., Wang, L., Cheng, X., Liu, Y., Schwebel, D. C., Liu, J., Qi, J., Hu, G., et al. (2017) · PLoS Medicine · doi:10.1371/journal.pmed.1002332 · Cited by 144 · see citing works

Pyrrolopyrrole aza-BODIPY analogues: a facile synthesis and intense fluorescence

Shimizu, S., Iino, T., Araki, Y., & Kobayashi, N. (2013) · Chemical Communications · doi:10.1039/c3cc38452g · Cited by 143 · see citing works

Diagnosis and current therapy of Wilson's disease

Ferenci, P. (2004) · Alimentary Pharmacology & Therapeutics · doi:10.1046/j.1365-2036.2003.01813.x · Cited by 141 · see citing works

Implementation and benchmarking of a novel analytical framework to clinically evaluate tumor-specific fluorescent tracers

Koller, M., Qiu, S.-Q., Linssen, M. D., Jansen, L., Kelder, W., de Vries, J., Kruithof, I. G., Zhang, G., Robinson, D. J., Nagengast, W. B., et al. (2018) · Nature Communications · doi:10.1038/s41467-018-05727-y · Cited by 139 · see citing works

Fluorescence optical imaging in anticancer drug delivery

Etrych, T., Lucas, H., Janoušková, O., Chytil, P., Mueller, T., & Mäder, K. (2016) · Journal of Controlled Release · doi:10.1016/j.jconrel.2016.02.022 · Cited by 137 · see citing works

Water-soluble BODIPY and aza-BODIPY dyes: synthetic progress and applications

Fan, G., Yang, L., & Chen, Z. (2014) · Frontiers of Chemical Science and Engineering · doi:10.1007/s11705-014-1445-7 · Cited by 134 · see citing works

Effect of physicochemical modification on the biodistribution and tumor accumulation of HPMA copolymers

Lammers, T., Kühnlein, R., Kissel, M., Šubr, V., Etrych, T., Pola, R., Pechar, M., Ulbrich, K., Storm, G., Huber, P. E., et al. (2005) · Journal of Controlled Release · doi:10.1016/j.jconrel.2005.09.010 · Cited by 131 · see citing works

A facile way to obtain near-infrared room-temperature phosphorescent soft materials based on Bodipy dyes

Zhang, T., Ma, X., & Tian, H. (2019) · Chemical Science · doi:10.1039/c9sc05502a · Cited by 130 · see citing works

Regulation of tumor immune suppression and cancer cell survival by CXCL1/2 elevation in glioblastoma multiforme

Hu, J., Zhao, Q., Kong, L.-Y., Wang, J., Yan, J., Xia, X., Jia, Z., Heimberger, A. B., & Li, S. (2021) · Science Advances · doi:10.1126/sciadv.abc2511 · Cited by 126 · see citing works

Real-Time Evaluation of Hydrogen Peroxide Injuries in Pulmonary Fibrosis Mice Models with a Mitochondria-Targeted Near-Infrared Fluorescent Probe

Song, X., Bai, S., He, N., Wang, R., Xing, Y., Lv, C., & Yu, F. (2021) · ACS Sensors · doi:10.1021/acssensors.0c02519 · Cited by 124 · see citing works

Nitric‐Oxide‐Releasing aza‐BODIPY: A New Near‐Infrared J‐Aggregate with Multiple Antibacterial Modalities

Bao, X., Zheng, S., Zhang, L., Shen, A., Zhang, G., Liu, S., & Hu, J. (2022) · Angewandte Chemie International Edition · doi:10.1002/anie.202207250 · Cited by 124 · see citing works

A Supramolecular Strategy to Engineering a Non-photobleaching and Near-Infrared Absorbing Nano-J-Aggregate for Efficient Photothermal Therapy

Su, M., Han, Q., Yan, X., Liu, Y., Luo, P., Zhai, W., Zhang, Q., Li, L., & Li, C. (2021) · ACS Nano · doi:10.1021/acsnano.0c09993 · Cited by 120 · see citing works

A Bright, Renal‐Clearable NIR‐II Brush Macromolecular Probe with Long Blood Circulation Time for Kidney Disease Bioimaging

Yao, C., Chen, Y., Zhao, M., Wang, S., Wu, B., Yang, Y., Yin, D., Yu, P., Zhang, H., & Zhang, F. (2022) · Angewandte Chemie International Edition · doi:10.1002/anie.202114273 · Cited by 117 · see citing works

The Liver Biopsy Diagnosis of Wilson’s Disease:Methods in Pathology

Ludwig, J., Moyer, T. P., & Rakela, J. (1994) · American Journal of Clinical Pathology · doi:10.1093/ajcp/102.4.443 · Cited by 114 · see citing works

Identification of kidney injury–released circulating osteopontin as causal agent of respiratory failure

Khamissi, F. Z., Ning, L., Kefaloyianni, E., Dun, H., Arthanarisami, A., Keller, A., Atkinson, J. J., Li, W., Wong, B. W., Dietmann, S., et al. (2022) · Science Advances · doi:10.1126/sciadv.abm5900 · Cited by 113 · see citing works

Spatiotemporal multiplexed immunofluorescence imaging of living cells and tissues with bioorthogonal cycling of fluorescent probes

Ko, J., Wilkovitsch, M., Oh, J., Köhler, R. H., Bolli, E., Pittet, M. J., Vinegoni, C., Sykes, D. B., Mikula, H., Weissleder, R., et al. (2022) · Nature Biotechnology · doi:10.1038/s41587-022-01339-6 · Cited by 111 · see citing works

Evolution of BODIPY/aza-BODIPY dyes for organic photoredox/energy transfer catalysis

Rana, P., Singh, N., Majumdar, P., & Singh, S. P. (2022) · Coordination Chemistry Reviews · doi:10.1016/j.ccr.2022.214698 · Cited by 109 · see citing works

Energy Migration Engineering of Bright Rare‐Earth Upconversion Nanoparticles for Excitation by Light‐Emitting Diodes

Zhong, Y., Rostami, I., Wang, Z., Dai, H., & Hu, Z. (2015) · Advanced Materials · doi:10.1002/adma.201502272 · Cited by 107 · see citing works

One-step synthesis of red/green dual-emissive carbon dots for ratiometric sensitive ONOO − probing and cell imaging

Liu, J., Dong, Y., Ma, Y., Han, Y., Ma, S., Chen, H., & Chen, X. (2018) · Nanoscale · doi:10.1039/c8nr04596h · Cited by 102 · see citing works

Near-Infrared Laser-Triggered In Situ Dimorphic Transformation of BF 2 -Azadipyrromethene Nanoaggregates for Enhanced Solid Tumor Penetration

Chen, Y., Zhang, X., Cheng, D., Zhang, Y., Liu, Y., Ji, L., Guo, R., Chen, H., Ren, X., Chen, Z., et al. (2020) · ACS Nano · doi:10.1021/acsnano.0c00118 · Cited by 102 · see citing works

Activated microglia targeting dendrimer–minocycline conjugate as therapeutics for neuroinflammation.

Sharma, R., Kim, S.-Y., Sharma, A., Zhang, Z., Kambhampati, S. P., Kannan, S., & Kannan, R. M. (2017) · Bioconjugate Chemistry · doi:10.1021/acs.bioconjchem.7b00569 · Cited by 100 · see citing works

Unique Double Intramolecular and Intermolecular Exciton Coupling in Ethene‐Bridged aza‐BODIPY Dimers for High‐Efficiency Near‐Infrared Photothermal Conversion and Therapy

Guo, X., Yang, J., Li, M., Zhang, F., Bu, W., Li, H., Wu, Q., Yin, D., Jiao, L., & Hao, E. (2022) · Angewandte Chemie International Edition · doi:10.1002/anie.202211081 · Cited by 100 · see citing works

Synthesis of N,N-difluoroboryl complexes of 3,3′-diarylazadiisoindolylmethenes

Donyagina, V. F., Shimizu, S., Kobayashi, N., & Lukyanets, E. A. (2008) · Tetrahedron Letters · doi:10.1016/j.tetlet.2008.08.026 · Cited by 96 · see citing works

Halogenated Aza‐BODIPY for Imaging‐Guided Synergistic Photodynamic and Photothermal Tumor Therapy

Zhao, M., Xu, Y., Xie, M., Zou, L., Wang, Z., Liu, S., & Zhao, Q. (2018) · Advanced Healthcare Materials · doi:10.1002/adhm.201800606 · Cited by 95 · see citing works

Subcellular Chemical Imaging: New Avenues in Cell Biology

Decelle, J., Veronesi, G., Gallet, B., Stryhanyuk, H., Benettoni, P., Schmidt, M., Tucoulou, R., Passarelli, M. K., Bohic, S., Clode, P. L., et al. (2020) · Trends in Cell Biology · doi:10.1016/j.tcb.2019.12.007 · Cited by 95 · see citing works

Trending: Radioactive and Fluorescent Bimodal/Hybrid Tracers as Multiplexing Solutions for Surgical Guidance

van Leeuwen, F. W. B., Schottelius, M., Brouwer, O. R., Vidal‐Sicart, S., Achilefu, S. A., Klode, J., Wester, H., & Buckle, T. (2019) · Journal of Nuclear Medicine · doi:10.2967/jnumed.119.228684 · Cited by 94 · see citing works

Non-invasive Reporter Gene Imaging of Cell Therapies, including T Cells and Stem Cells

Ashmore‐Harris, C., Iafrate, M., Saleem, A., & Fruhwirth, G. O. (2020) · Molecular Therapy · doi:10.1016/j.ymthe.2020.03.016 · Cited by 91 · see citing works

An Activatable Polymeric Nanoprobe for Fluorescence and Photoacoustic Imaging of Tumor‐Associated Neutrophils in Cancer Immunotherapy

Zhang, Y., He, S., Xu, C., Jiang, Y., Miao, Q., & Pu, K. (2022) · Angewandte Chemie International Edition · doi:10.1002/anie.202203184 · Cited by 91 · see citing works

Accessing Near-Infrared-Absorbing BF2-Azadipyrromethenes via a Push–Pull Effect

Jiao, L., Wu, Y., Wang, S., Hu, X., Zhang, P., Yu, C., Cong, K., Meng, Q., Hao, E., & Vicente, M. G. H. (2014) · The Journal of Organic Chemistry · doi:10.1021/jo402160b · Cited by 90 · see citing works

Water-Soluble Aza-BODIPYs: Biocompatible Organic Dyes for High Contrast <i>In Vivo</i> NIR-II Imaging

Godard, A., Kalot, G., Pliquett, J., Busser, B., Le Guével, X., Wegner, K. D., Resch-Genger, U., Rousselin, Y., Coll, J.-L., Denat, F., et al. (2020) · Bioconjugate Chemistry · doi:10.1021/acs.bioconjchem.0c00175 · Cited by 90 · see citing works

Recent progress in near-infrared photoacoustic imaging

Du, J., Yang, S., Qiao, Y., Lu, H., & Dong, H. (2021) · Biosensors and Bioelectronics · doi:10.1016/j.bios.2021.113478 · Cited by 86 · see citing works

Exciton Coupling of Merocyanine Dyes from H- to J-type in the Solid State by Crystal Engineering

Liess, A., Lv, A., Arjona‐Esteban, A., Bialas, D., Krause, A., Stepanenko, V., Stolte, M., & Würthner, F. (2017) · Nano Letters · doi:10.1021/acs.nanolett.6b04995 · Cited by 85 · see citing works

Hydrogen Sulfide and Polysulfide Signaling

Kimura, H. (2017) · Antioxidants and Redox Signaling · doi:10.1089/ars.2017.7076 · Cited by 84 · see citing works

Modifying the Body Distribution of HPMA-Based Copolymers by Molecular Weight and Aggregate Formation

Allmeroth, M., Moderegger, D., Biesalski, B., Koynov, K., Rösch, F., Thews, O., & Zentel, R. (2011) · Biomacromolecules · doi:10.1021/bm2005774 · Cited by 82 · see citing works

Synthesis and Properties of BF 2 -3,3′-Dimethyldiarylazadipyrromethene Near-Infrared Fluorophores

Wu, D., & O’Shea, D. F. (2013) · Organic Letters · doi:10.1021/ol401434c · Cited by 82 · see citing works

A Two-Photon Fluorescent Probe for Imaging Endogenous ONOO– near NMDA Receptors in Neuronal Cells and Hippocampal Tissues

Lee, D., Lim, C. S., Ko, G., Kim, D., Cho, M. K., Nam, S., Kim, H. M., & Yoon, J. (2018) · Analytical Chemistry · doi:10.1021/acs.analchem.8b01960 · Cited by 80 · see citing works

All-in-one mitochondria-targeted NIR-II fluorophores for cancer therapy and imaging

Zheng, Y., Li, Q., Wu, J., Luo, Z., Zhou, W., Li, A., Chen, Y., Rouzi, T., Tian, T., Zhou, H., et al. (2020) · Chemical Science · doi:10.1039/d0sc04727a · Cited by 79 · see citing works

Rationally designed Ru( ii )-metallacycle chemo-phototheranostic that emits beyond 1000 nm

Li, C., Xu, Y., Tu, L., Choi, M., Fan, Y., Chen, X., Sessler, J. L., Kim, J. S., & Sun, Y. (2022) · Chemical Science · doi:10.1039/d2sc01518h · Cited by 79 · see citing works

Tubular cell polyploidy protects from lethal acute kidney injury but promotes consequent chronic kidney disease

Chiara, L. D., Conte, C., Semeraro, R., Díaz-Bulnes, P., Angelotti, M. L., Mazzinghi, B., Molli, A., Antonelli, G., Landini, S., Melica, M. E., et al. (2022) · Nature Communications · doi:10.1038/s41467-022-33110-5 · Cited by 79 · see citing works

Preclinical Validation of the Utility of BLZ-100 in Providing Fluorescence Contrast for Imaging Spontaneous Solid Tumors

Fidel, J. L., Kennedy, K. C., Dernell, W. S., Hansen, S. J., Wiss, V., Stroud, M. R., Molho, J. I., Knoblaugh, S. E., Meganck, J. A., Olson, J. M., et al. (2015) · Cancer Research · doi:10.1158/0008-5472.can-15-0471 · Cited by 77 · see citing works

Nitric oxide imaging in cancer enabled by steric relaxation of a photoacoustic probe platform

Reinhardt, C. J., Xu, R., & Chan, J. (2020) · Chemical Science · doi:10.1039/c9sc05600a · Cited by 77 · see citing works

A tumor-mitochondria dual targeted aza-BODIPY-based nanotheranostic agent for multimodal imaging-guided phototherapy

Chen, D., Zhang, J., Tang, Y., Huang, X., Shao, J., Si, W., Ji, J., Zhang, Q., Huang, W., & Dong, X. (2018) · Journal of Materials Chemistry B · doi:10.1039/c8tb01347k · Cited by 76 · see citing works

Supramolecular J-aggregates of aza-BODIPY by steric and π–π nteractions for NIR-II phototheranostics

Tian, Y., Yin, D., Cheng, Q., Dang, H., Teng, C., & Yan, L. (2022) · Journal of Materials Chemistry B · doi:10.1039/d1tb02820k · Cited by 76 · see citing works

NIR fluorescence imaging and treatment for cancer immunotherapy

Kang, H., Kang, M., Kashiwagi, S., & Choi, H. S. (2022) · Journal for ImmunoTherapy of Cancer · doi:10.1136/jitc-2022-004936 · Cited by 76 · see citing works

Molecular Engineering of Near-Infrared Light-Responsive BODIPY-Based Nanoparticles with Enhanced Photothermal and Photoacoustic Efficiencies for Cancer Theranostics

Gao, D., Zhang, B., Liu, Y., Hu, D., Sheng, Z., Zhang, X., & Yuan, Z. (2019) · Theranostics · doi:10.7150/thno.34418 · Cited by 72 · see citing works

Synthesis, Crystal Structure, and the Deep Near-Infrared Absorption/Emission of Bright AzaBODIPY-Based Organic Fluorophores

Sheng, W., Wu, Y., Yu, C., Bobadova‐Parvanova, P., Hao, E., & Jiao, L. (2018) · Organic Letters · doi:10.1021/acs.orglett.8b00820 · Cited by 70 · see citing works

A Promising Family of Fluorescent Water-Soluble aza-BODIPY Dyes for in Vivo Molecular Imaging

Pliquett, J., DuBois, A. S., Racoeur, C., Mabrouk, N., Amor, S., Lescure, R., Bettaı̈eb, A., Collin, B., Bernhard, C., Denat, F., et al. (2019) · Bioconjugate Chemistry · doi:10.1021/acs.bioconjchem.8b00795 · Cited by 70 · see citing works

Modified chitosan for effective renal delivery of siRNA to treat acute kidney injury

Tang, W., Panja, S., Jogdeo, C. M., Tang, S., Ding, L., Yu, A., Foster, K. W., Dsouza, D. L., Chhonker, Y. S., Jensen‐Smith, H. C., et al. (2022) · Biomaterials · doi:10.1016/j.biomaterials.2022.121562 · Cited by 70 · see citing works

Conformationally restricted and ring-fused aza-BODIPYs as promising near infrared absorbing and emitting dyes

Wang, J., Yu, C., Hao, E., & Jiao, L. (2022) · Coordination Chemistry Reviews · doi:10.1016/j.ccr.2022.214709 · Cited by 70 · see citing works

Update on multiparametric MRI of urinary bladder cancer

van der Pol, C. B., Chung, A. D., Lim, C. S., Gandhi, N., Tu, W., McInnes, M. D. F., & Schieda, N. (2018) · Journal of Magnetic Resonance Imaging · doi:10.1002/jmri.26294 · Cited by 68 · see citing works

Water-solubilised BF 2 -chelated tetraarylazadipyrromethenes

Tasior, M., Murtagh, J. E., Frimannsson, D. O., McDonnell, S. O., & O’Shea, D. F. (2009) · Organic & Biomolecular Chemistry · doi:10.1039/b919546g · Cited by 65 · see citing works

Molecular imaging of HPMA copolymers: Visualizing drug delivery in cell, mouse and man☆

Lu, Z. (2010) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2009.12.007 · Cited by 63 · see citing works

Evaluation of Glutathione S-Transferase Inhibition Effects on Idiopathic Pulmonary Fibrosis Therapy with a Near-Infrared Fluorescent Probe in Cell and Mice Models

He, N., Bai, S., Huang, Y. L., Xing, Y., Chen, L., Yu, F., & Lv, C. (2019) · Analytical Chemistry · doi:10.1021/acs.analchem.9b00713 · Cited by 58 · see citing works

PET/Fluorescence Imaging: An Overview of the Chemical Strategies to Build Dual Imaging Tools

Ariztia, J., Solmont, K., Pellegrini-Moïse, N., Specklin, S., Heck, M., Lamandé‐Langle, S., & Kühnast, B. (2022) · Bioconjugate Chemistry · doi:10.1021/acs.bioconjchem.1c00503 · Cited by 54 · see citing works

Activity-based photoacoustic probe for biopsy-free assessment of copper in murine models of Wilson’s disease and liver metastasis

Lucero, M. Y., Tang, Y., Zhang, C. J., Su, S., Forzano, J. A., Garcia, V., Huang, X., Moreno, D., & Chan, J. (2021) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2106943118 · Cited by 50 · see citing works

Recent advances of NIR dyes of pyrrolopyrrole cyanine and pyrrolopyrrole aza-BODIPY: Synthesis and application

Wang, L., Xiong, Z., Ran, X., Tang, H., & Cao, D. (2021) · Dyes and Pigments · doi:10.1016/j.dyepig.2021.110040 · Cited by 50 · see citing works

NIR-II bioimaging of small molecule fluorophores: From basic research to clinical applications

Li, C., Guan, X., Zhang, X., Zhou, D., Son, S., Xu, Y., Deng, M., Guo, Z., Sun, Y., & Kim, J. S. (2022) · Biosensors and Bioelectronics · doi:10.1016/j.bios.2022.114620 · Cited by 49 · see citing works

[a]-Phenanthrene-Fused BF2 Azadipyrromethene (AzaBODIPY) Dyes as Bright Near-Infrared Fluorophores

Sheng, W., Cui, J., Ruan, Z., Yan, L., Wu, Q., Yu, C., Wei, Y., Hao, E., & Jiao, L. (2017) · The Journal of Organic Chemistry · doi:10.1021/acs.joc.7b01803 · Cited by 47 · see citing works

BF 2 -azadipyrromethene NIR-emissive fluorophores with research and clinical potential

Daly, H. C., Durán‐Sampedro, G., Bon, C., Wu, D., Ismail, G., Cahill, R. A., & O’Shea, D. F. (2017) · European Journal of Medicinal Chemistry · doi:10.1016/j.ejmech.2017.04.051 · Cited by 46 · see citing works

Synthesis and assessment of a maleimide functionalized BF 2 azadipyrromethene near-infrared fluorochrome

Wu, D., Cheung, S., Devocelle, M. C., Zhang, L., Chen, Z., & O’Shea, D. F. (2015) · Chemical Communications · doi:10.1039/c5cc06137g · Cited by 44 · see citing works

Multimodal Imaging of Neurometabolic Pathology due to Traumatic Brain Injury

Horn, J. D. V., Bhattrai, A., & Andrei Irimia, A. (2016) · Trends in Neurosciences · doi:10.1016/j.tins.2016.10.007 · Cited by 44 · see citing works

Discovery of an Amino Acid-Modified Near-Infrared Aza-BODIPY Photosensitizer as an Immune Initiator for Potent Photodynamic Therapy in Melanoma

Yu, Z., Wang, H., Chen, Z., Dong, X., Zhao, W., Shi, Y., & Zhu, Q. (2022) · Journal of Medicinal Chemistry · doi:10.1021/acs.jmedchem.1c02154 · Cited by 42 · see citing works

Optical strong coupling in microcavities containing J-aggregates absorbing in near-infrared spectral range

Wenus, J., Ceccarelli, S., Lidzey, D. G., Tolmachev, A. I., Slominskii, J. L., & Bricks, J. L. (2006) · Organic Electronics · doi:10.1016/j.orgel.2006.06.006 · Cited by 40 · see citing works

Surfactant-stripped J-aggregates of azaBODIPY derivatives: All-in-one phototheranostics in the second near infrared window

Zhang, Y., Tao, H., Li, Q., Sheng, W., Xu, Y., Hao, E., Chen, M., Liu, Z., & Feng, L. (2020) · Journal of Controlled Release · doi:10.1016/j.jconrel.2020.07.017 · Cited by 40 · see citing works

Rigidity Bridging Flexibility to Harmonize Three Excited‐State Deactivation Pathways for NIR‐II‐Fluorescent‐Imaging‐Guided Phototherapy

Huang, W., Yang, H., Hu, Z., Fan, Y., Guan, X., Feng, W., Liu, Z., & Sun, Y. (2021) · Advanced Healthcare Materials · doi:10.1002/adhm.202101003 · Cited by 40 · see citing works

Ratiometric Detection of H 2 S in Liver Injury by Activated Two-Wavelength Photoacoustic Imaging

Wu, R., Chen, Z., Huo, H., Chen, L., Su, L., Zhang, X. K., Wu, Y., Yao, Z., Xiao, S., Du, W., et al. (2022) · Analytical Chemistry · doi:10.1021/acs.analchem.2c01571 · Cited by 39 · see citing works

Optical limiting properties of 3,5-diphenyldibenzo-azaBODIPY at 532 nm

Kubheka, G., Achadu, O. J., Mack, J. P., & Nyokong, T. (2017) · New Journal of Chemistry · doi:10.1039/c7nj01503h · Cited by 38 · see citing works

Functional aza-boron dipyrromethenes for subcellular imaging and organelle-specific photodynamic therapy

Wang, Q., Ng, D. K. P., & Lo, P. (2018) · Journal of Materials Chemistry B · doi:10.1039/c8tb00593a · Cited by 38 · see citing works

Engineering a Ratiometric Photoacoustic Probe with a Hepatocyte-Specific Targeting Ability for Liver Injury Imaging

Fan, X., Yang, W., Ren, T., Xu, S., Gong, X., Zhang, X., & Yuan, L. (2022) · Analytical Chemistry · doi:10.1021/acs.analchem.1c05026 · Cited by 38 · see citing works

Recent Advances of the Near-infrared Fluorescent aza-BODIPY Dyes

Jiang, X., Li, S., Guan, J., Fang, T., Liu, X., & Xiao, L. (2016) · Current Organic Chemistry · doi:10.2174/1385272820666160229224354 · Cited by 37 · see citing works

In Vivo Assembly and Disassembly of Probes to Improve Near‐Infrared Optical Bioimaging

Zhao, M., Li, B., Fan, Y., & Zhang, F. (2019) · Advanced Healthcare Materials · doi:10.1002/adhm.201801650 · Cited by 37 · see citing works

Near-Infrared absorbing J-Aggregates of boron dipyrromethene for high efficient photothermal therapy

Xia, J., Li, Z., Xie, Z., & Zheng, M. J. (2021) · Journal of Colloid and Interface Science · doi:10.1016/j.jcis.2021.04.086 · Cited by 37 · see citing works

Cystathionine-Gamma-Lyase Gene Deletion Protects Mice against Inflammation and Liver Sieve Injury following Polymicrobial Sepsis

Gaddam, R. R., Fraser, R., Badiei, A., Chambers, S. T., Cogger, V. C., Couteur, D. G. L., Ishii, I., & Bhatia, M. (2016) · PLoS ONE · doi:10.1371/journal.pone.0160521 · Cited by 36 · see citing works

Tuning Near-Infrared Absorbing Donor Materials: A Study of Electronic, Optical, and Charge-Transport Properties of aza-BODIPYs

Schellhammer, K. S., Li, T., Zeika, O., Körner, C., Leo, K., Ortmann, F., & Cuniberti, G. (2017) · Chemistry of Materials · doi:10.1021/acs.chemmater.7b00653 · Cited by 36 · see citing works

Raman microspectroscopy and Raman imaging reveal biomarkers specific for thoracic aortic aneurysms

Sugiyama, K., Marzi, J., Alber, J., Brauchle, E., Ando, M., Yamashiro, Y., Ramkhelawon, B., Schenke‐Layland, K., & Yanagisawa, H. (2021) · Cell Reports Medicine · doi:10.1016/j.xcrm.2021.100261 · Cited by 36 · see citing works

J- and H-aggregates of heavy-atom-free Aza-BODIPY dyes with high 1O2 generation efficiency and photodynamic therapy potential

Liu, Y., Zhang, Y., Liu, G., & Xing, G. (2022) · Dyes and Pigments · doi:10.1016/j.dyepig.2022.110813 · Cited by 34 · see citing works

Application of urine proteomics for biomarker discovery in drug-induced liver injury

van Swelm, R. P. L., Kramers, C., Masereeuw, R., & Rüssel, F. G. M. (2014) · Critical Reviews in Toxicology · doi:10.3109/10408444.2014.931341 · Cited by 33 · see citing works

64-Slice CT urography: 30 months of clinical experience

Martingano, P., Stacul, F., Cavallaro, M. F. M., Casagrande, F., Cernic, S., Belgrano, M., & Cova, M. (2010) · La radiologia medica · doi:10.1007/s11547-010-0567-3 · Cited by 31 · see citing works

Acetaminophen-Induced Hepatotoxicity in a Liver Tissue Model Consisting of Primary Hepatocytes Assembling around an Endothelial Cell Network

Toyoda, Y., Tamai, M., Kashikura, K., Kobayashi, S., Fujiyama, Y., Soga, T., & Tagawa, Y. (2011) · Drug Metabolism and Disposition · doi:10.1124/dmd.111.041137 · Cited by 31 · see citing works

A molybdenum-based nanoplatform with multienzyme mimicking capacities for oxidative stress-induced acute liver injury treatment

Zhang, Z., Zhao, J., Chen, Z., Wu, H., & Wang, S. (2022) · Inorganic Chemistry Frontiers · doi:10.1039/d2qi02318k · Cited by 31 · see citing works

Fibrogenic Disorders in Human Diseases: From Inflammation to Organ Dysfunction

Juillerat‐Jeanneret, L., Aubert, J., Mikulic, J., & Golshayan, D. (2018) · Journal of Medicinal Chemistry · doi:10.1021/acs.jmedchem.8b00294 · Cited by 30 · see citing works

Aza-BODIPY based probe for photoacoustic imaging of ONOO− in vivo

Ma, D., Hou, S., Bae, C., Pham, T. C., Lee, S., & Zhou, X. M. (2021) · Chinese Chemical Letters · doi:10.1016/j.cclet.2021.05.048 · Cited by 30 · see citing works

NIR-II Dyad-Doped Ratiometric Nanosensor with Enhanced Spectral Fidelity in Biological Media for In Vivo Biosensing

Yu, P., Yan, K., Wang, S., Yao, C., Lei, Z., Tang, Y., & Zhang, F. (2022) · Nano Letters · doi:10.1021/acs.nanolett.2c04084 · Cited by 30 · see citing works

Novel butterfly-shaped AIE-active pyrrolopyrrole aza -BODIPYs: synthesis, bioimaging and diamine/polyamine detection

Li, W., Wang, L., Zhang, C., Ran, X., Tang, H., & Cao, D. (2022) · Journal of Materials Chemistry C · doi:10.1039/d2tc00005a · Cited by 29 · see citing works

Paramagnetic Phospholipid-Based Micelles Targeting VCAM-1 Receptors for MRI Visualization of Inflammation

Pagoto, A., Stefanìa, R., Garello, F., Arena, F., Digilio, G., Aime, S., & Terreno, E. (2016) · Bioconjugate Chemistry · doi:10.1021/acs.bioconjchem.6b00308 · Cited by 26 · see citing works

Aza-BODIPY based polymeric nanoparticles for cancer cell imaging

Chansaenpak, K., Tanjindaprateep, S., Chaicharoenaudomrung, N., Weeranantanapan, O., Noisa, P., & Kamkaew, A. (2018) · RSC Advances · doi:10.1039/c8ra08145j · Cited by 26 · see citing works

Vascular Cell Adhesion Molecule-Targeted MS2 Viral Capsids for the Detection of Early-Stage Atherosclerotic Plaques

Aanei, I. L., Huynh, T. L., Seo, Y., & Francis, M. B. (2018) · Bioconjugate Chemistry · doi:10.1021/acs.bioconjchem.8b00453 · Cited by 25 · see citing works

Pyrrolopyrrole aza boron dipyrromethene based two-photon fluorescent probes for subcellular imaging

Zhou, Y., Ma, C., Gao, N., Wang, Q., Lo, P., Wong, K. S., Xu, Q., Kinoshita, T., & Ng, D. K. P. (2018) · Journal of Materials Chemistry B · doi:10.1039/c8tb01832d · Cited by 24 · see citing works

Development of an Easily Bioconjugatable Water-Soluble Single-Photon Emission-Computed Tomography/Optical Imaging Bimodal Imaging Probe Based on the aza-BODIPY Fluorophore

Privat, M., Bellaye, P., Lescure, R., Massot, A., Baffroy, O., Moreau, M., Racoeur, C., Marcion, G., Denat, F., Bettaı̈eb, A., et al. (2021) · Journal of Medicinal Chemistry · doi:10.1021/acs.jmedchem.1c00450 · Cited by 24 · see citing works

Targeted Dual-Modal PET/SPECT-NIR Imaging: From Building Blocks and Construction Strategies to Applications

Usama, S. M., Marker, S. C., Vargas, S. H., AghaAmiri, S., Ghosh, S. C., Ikoma, N., Cao, H. S. T., Schnermann, M. J., & Azhdarinia, A. (2022) · Cancers · doi:10.3390/cancers14071619 · Cited by 24 · see citing works

An aza-BODIPY-based NIR-II luminogen enables efficient phototheranostics

Yang, N., Song, S., Liu, C., Ren, J., Wang, X., Zhu, S., & Yu, C. (2022) · Biomaterials Science · doi:10.1039/d2bm00670g · Cited by 24 · see citing works

A fluorinated aza-BODIPY derivative for NIR fluorescence/PA/ 19 F MR tri-modality in vivo imaging

Liu, L., Yuan, Y., Yang, Y., McMahon, M. T., Chen, S., & Zhou, X. H. (2019) · Chemical Communications · doi:10.1039/c9cc01253b · Cited by 22 · see citing works

Application of Fluorescent Probes in Reactive Oxygen Species Disease Model

Niu, P., Zhu, J., Wei, L., & Liu, X. (2022) · Critical Reviews in Analytical Chemistry · doi:10.1080/10408347.2022.2080495 · Cited by 21 · see citing works

PEGylated BF2-Azadipyrromethene (NIR-AZA) fluorophores, for intraoperative imaging

Wu, D., Daly, H. C., Conroy, E., Li, B., Gallagher, W. M., Cahill, R. A., & O’Shea, D. F. (2018) · European Journal of Medicinal Chemistry · doi:10.1016/j.ejmech.2018.10.046 · Cited by 20 · see citing works

Rational Design of Near‐Infrared Aza‐Platinum‐Dipyrromethene‐Based Nanophototherapy Agent with Multistage Enhancement for Synergistic Antitumor Therapeutics

Xu, Y., Zhao, M., Zhou, Y., Wang, J., Li, M., Li, F., Lv, W. Y., Liu, S., & Zhao, Q. (2021) · Small Structures · doi:10.1002/sstr.202100094 · Cited by 20 · see citing works

One-Pot Access to Ethylene-Bridged BODIPY Dimers and Trimers through Single-Electron Transfer Chemistry

Gong, Q., Cheng, K. M., Wu, Q., Li, W., Yu, C., Jiao, L., & Hao, E. (2021) · The Journal of Organic Chemistry · doi:10.1021/acs.joc.1c01824 · Cited by 19 · see citing works

Aza-BODIPY encapsulated polymeric nanoparticles as an effective nanodelivery system for photodynamic cancer treatment

Treekoon, J., Chansaenpak, K., Tumcharern, G., Zain, Z. S. Z., Lee, H. B., Kue, C. S., & Kamkaew, A. (2021) · Materials Chemistry Frontiers · doi:10.1039/d0qm00891e · Cited by 18 · see citing works

1,7‐Difluorophore‐Substituted AzaBODIPYs

Koch, A., & Ravikanth, M. (2017) · European Journal of Organic Chemistry · doi:10.1002/ejoc.201701396 · Cited by 11 · see citing works

Access to Pyridinyl or Pyridinium Aza‐BODIPYs with Tunable Near‐Infrared Fluorescence through ICT from 4‐Pyridinyl Pyrroles**

Liu, C., Jin, Y., Ji, X., Zhao, W., & Dong, X. (2022) · Chemistry - A European Journal · doi:10.1002/chem.202201503 · Cited by 11 · see citing works

Activatable Optical Probes for Fluorescence and Photoacoustic Imaging of Drug‐Induced Liver Injury

Chen, L., Xu, Z. C., & Jiang, X. (2022) · Advanced NanoBiomed Research · doi:10.1002/anbr.202200097 · Cited by 10 · see citing works

A dual-channel fluorescent ratio probe with hypoxia targeting and hypoxia activation capacity for tumour imaging

Yuan, P., Xu, X., Xiao, B., Shi, X., Zhang, W., Xu, H., Piao, Y., Shen, Y., Slater, N. K. H., & Tang, J. (2022) · Polymer Chemistry · doi:10.1039/d2py00313a · Cited by 7 · see citing works

Recent Advances in Fluorescence Imaging of Pulmonary Fibrosis in Animal Models

Liu, Z., Tang, X., Zhu, Z., Ma, X., Zhou, W., & Guan, W. (2021) · Frontiers in Molecular Biosciences · doi:10.3389/fmolb.2021.773162 · Cited by 6 · see citing works

Synthesis of a Single‐Stranded DNA Aptamer Modified Near‐infrared, Water‐Soluble Fluorophore for Lung Cancer Cell Imaging

He, X., Li, H., Liu, S., Li, Y., Lin, X., Zheng, H., Zhou, Z., & Zeng, D. (2022) · ChemistrySelect · doi:10.1002/slct.202103821 · Cited by 5 · see citing works

Focus on optimizing treatment of coronary heart disease

Agewall, S. (2022) · European Heart Journal - Cardiovascular Pharmacotherapy · doi:10.1093/ehjcvp/pvac039 · Cited by 1 · see citing works

Transformative Impact of Nanocarrier‐Mediated Drug Delivery: Overcoming Biological Barriers and Expanding Therapeutic Horizons

Kim, M., Shin, M., Zhao, Y., Ghosh, M., & Son, Y. (2024) · Small Science · doi:10.1002/smsc.202400280 · Cited by 101 · see citing works

Near‐Infrared Absorbing Aza‐BODIPY Dyes for Optoelectronic Applications

Pinjari, D., Patil, Y., & Misra, R. (2024) · Chemistry - An Asian Journal · doi:10.1002/asia.202400167 · Cited by 31 · see citing works

Near-infrared BODIPY-based theranostic agents for photothermal and combinatory therapy of cancers, where do we stand in year 2025

Iqbal, M. S., Ahmad, H., Chen, Y., Huang, H., & Guo, B. (2025) · Coordination Chemistry Reviews · doi:10.1016/j.ccr.2025.216781 · Cited by 27 · see citing works

Development of BODIPY-based fluorescent probes for imaging Aβ aggregates and lipid droplet viscosity

Li, K., Wang, Y., Li, Y., Shi, W., & Yan, J. (2024) · Talanta · doi:10.1016/j.talanta.2024.126362 · Cited by 24 · see citing works

Organic small-molecule NIR-II fluorophores for tumor phototheranostics

Xiang, D., Wang, Z., Zheng, H., Tang, Y., & Li, Q. (2026) · Light: Science &amp; Applications · doi:10.1038/s41377-026-02212-w · Cited by 22 · see citing works

Self‐Assembled (Aza)BODIPY Dyes for Biomedical in Vivo Imaging

Albers, A., Masthoff, M., & Fernández, G. (2026) · Angewandte Chemie International Edition · doi:10.1002/anie.202525491 · Cited by 16 · see citing works

Broad-Band-Capturing Tetracyanobutadiene-Incorporated Phenothiazine-azaBODIPY Push–Pull Systems: Excited State Charge Separation and Relaxation Dynamics

Alsaleh, A. Z., Pinjari, D., Das, S., Misra, R., & D'Souza, F. W. (2024) · The Journal of Physical Chemistry C · doi:10.1021/acs.jpcc.4c00583 · Cited by 12 · see citing works

Comparison of the In Vitro and In Vivo Behavior of a Series of NIR-II-Emitting Aza-BODIPYs Containing Different Water-Solubilizing Groups and Their Trastuzumab Antibody Conjugates

Chazeau, E., Fabre, C., Privat, M., Godard, A., Racoeur, C., Bodio, E., Busser, B., Wegner, K. D., Sancey, L., Paul, C., et al. (2024) · Journal of Medicinal Chemistry · doi:10.1021/acs.jmedchem.3c02139 · Cited by 11 · see citing works

Organic Nanomaterials Based on Aza-Boron Dipyrromethene with Aggregation-Induced Emission for NIR-II Fluorescence Imaging-Guided Photothermal Therapy

Chen, J., Sha, Q., Rehman, M. U., Wu, M., Hu, Z., & Wu, F. (2024) · ACS Applied Nano Materials · doi:10.1021/acsanm.4c04398 · Cited by 11 · see citing works

Spectral properties and anticancer activity of novel cisplatin-BODIPY conjugates

Ksenofontova, K. V., Ksenofontov, A. A., Kerner, A. A., Molchanov, E. E., Gessel, T. V., Galembikova, A. R., Krestova, A. N., Borisovskaya, E. P., Anatolevich, K. I., & Boichuk, S. (2025) · Optical Materials · doi:10.1016/j.optmat.2025.116680 · Cited by 11 · see citing works

Theoretical science-powered electrochemical and fluorescent systems for clinical diagnosis and environmental monitoring

Malahom, N., Darai, N., Jampasa, S., Özer, T., Injongkol, Y., & Paisuwan, W. (2025) · Microchemical Journal · doi:10.1016/j.microc.2025.114101 · Cited by 8 · see citing works

Modulating the two photon absorption features of aza-BODIPY derivatives depending on the electron-donating substituents in near-IR region

Doğan, A., Yılmaz, H., Karatay, A., Yıldız, E. A., Sevinç, G., Boyacıoğlu, B., Ünver, H., Hayvalı, M., & Elmalı, A. (2025) · Synthetic Metals · doi:10.1016/j.synthmet.2025.117887 · Cited by 7 · see citing works

Thieno[3,2- b ]thiophene-based bridged BODIPY dimers: synthesis, electrochemistry, and one- and two-photon photophysical properties

Chai, Z., Gu, T., Beau, A., Bolze, F., Gros, C. P., Liang, X., Shi, D., & Xu, H. (2024) · Dalton Transactions · doi:10.1039/d4dt02655a · Cited by 6 · see citing works

Analyte-Induced Restriction of Intramolecular Rotation: Turn-On aza-BODIPY Sensor for Biothiol Detection in Aqueous Media

Sadıkoğulları, B. C., & Özdemir, A. D. (2025) · Organic Letters · doi:10.1021/acs.orglett.5c02543 · Cited by 6 · see citing works

Halogenated Bis(donor)‐aza‐BODIPY System for Inducing NIR Excitation: Effect of Thiophene and Aminophenyl Donors on Optical Properties and in vitro Tests for Breast Cancer

Rodríguez-Mayor, A. V., Rodriguez, M. A., Ramos‐Ortíz, G., Bañuelos‐Hernández, A. E., Pérez‐Hernández, N., & Santillan, R. L. (2025) · ChemistrySelect · doi:10.1002/slct.202406201 · Cited by 6 · see citing works

Near-infrared emitting aza-BODIPY fluorophores, impact of N,N-dialkylamino groups on the photophysical properties: synthesis, characterization, and computational studies

Tajani, W., Verrieux, L., Sickinger, A., Godard, A., Rouillon, J., Goze, C., Dalonneau, F., Rousselin, Y., Maury, O., Sancey, L., et al. (2025) · Dyes and Pigments · doi:10.1016/j.dyepig.2025.112773 · Cited by 6 · see citing works

A NIR-Fluorochrome for Live Cell Dual Emission and Lifetime Tracking from the First Plasma Membrane Interaction to Subcellular and Extracellular Locales

Booth, E., Garrè, M., Wu, D., Daly, H. C., & O’Shea, D. F. (2024) · Molecules · doi:10.3390/molecules29112474 · Cited by 5 · see citing works

Evaluation of near-infrared two-photon absorption response and excited state dynamics of asymmetric aza-BODIPY derivatives

Doğan, A., Yılmaz, H., Yıldız, E. A., Sevinç, G., Arı, F., Ünver, H., Boyacıoğlu, B., Hayvalı, M., Elmalı, A., & Karatay, A. (2025) · Spectrochimica Acta Part A Molecular and Biomolecular Spectroscopy · doi:10.1016/j.saa.2025.127010 · Cited by 5 · see citing works

Multifunctional boron-dipyrromethene platforms for disease diagnosis and therapy: Advances in bioimaging, and phototherapeutics

Yang, Z., Liu, Y., Xie, Z., & Zheng, M. J. (2026) · Journal of Photochemistry and Photobiology C Photochemistry Reviews · doi:10.1016/j.jphotochemrev.2026.100739 · Cited by 4 · see citing works

Machine learning-aided algorithm for predicting spectral properties and cytotoxicity of BODIPY-appended platinum complexes

Lukanov, M. M., Ksenofontova, K. V., Kerner, A. A., & Ksenofontov, A. A. (2025) · Optical Materials · doi:10.1016/j.optmat.2025.116703 · Cited by 4 · see citing works

Investigating XC-functionals towards describing experimentally relevant excited-state properties of NIR-BODIPY derivatives

Fraiponts, M., Maes, W., & Champagne, B. R. (2025) · Physical Chemistry Chemical Physics · doi:10.1039/d5cp01830g · Cited by 3 · see citing works

Advances in near-infrared fluorescence imaging for biomedicine

Wu, H., Li, X., Liu, Z., Song, F., Cai, R., Chen, H., & Zhang, G. (2026) · Coordination Chemistry Reviews · doi:10.1016/j.ccr.2026.217892 · Cited by 4 · see citing works

Photothermal-chemotherapy: the emerging supramolecular photothermal molecules and the recent advances

Wong, W., Ren, Y., & Leung, F. K. (2024) · Elsevier eBooks · doi:10.1016/b978-0-443-13937-6.00007-x · Cited by 2 · see citing works

Computational Design and Quantum-Chemical Evaluation of Five Push–Pull Molecules with Narrow Bandgaps

Al-Araji, R. R. (2025) · Chemical Interactions · doi:10.64354/ofon.ci.2.1.52 · Cited by 1 · see citing works

The evolution of Near-Infrared (NIR) light: From fundamental spectroscopy to biomedical applications

Wong, K., Li, L., Xing, B., Zhang, T., & Jiang, L. (2024) · Journal of Luminescence · doi:10.1016/j.jlumin.2024.120466 · Cited by 1 · see citing works

Design and synthesis of fluorescent BODIPY derivatives with D-A structure for cancer cell imaging

Xiao, Y., Tong, S., Yang, M., Lin, X., Xu, M., & Wu, F. (2024) · Journal of Porphyrins and Phthalocyanines · doi:10.1142/s1088424624500391

Polyconjugated Aromatic Ligands as Antibiofilm AgentsPreprint

Sadıkoğulları, B. C., Kaya, S., Korkmaz, B. İ. O., Özdemir, A. D., & Merey, G. (2025) · SSRN Electronic Journal · doi:10.2139/ssrn.5265431

Control of biofilm formation at molecular level by using polyconjugated aromatic ligands

Sadıkoğulları, B. C., Kaya, S., Korkmaz, B. I. O., Ozdemir, A. D., & Merey, G. (2025) · Journal of the Indian Chemical Society · doi:10.1016/j.jics.2025.102351

Selbstassemblierte (Aza‐)BODIPY Farbstoffe für Biomedizinische In Vivo Bildgebung

Albers, A., Masthoff, M., & Fernández, G. (2026) · Angewandte Chemie · doi:10.1002/ange.202525491

Modulation of the electronic structure and sensing performance toward nitroaromatic explosives of aza-BODIPY derivatives through substituent effect

Uysal, E. C., Sadıkoğulları, B. C., Sütay, B., Karagöz, B., & Özdemir, A. D. (2026) · Dyes and Pigments · doi:10.1016/j.dyepig.2026.113959

Bridge-atom substitution strategy to extend the wavelength of organic fluorophores for biological application

Huang, R., Li, H., Zhu, H., Hu, L., He, L., Hao, Y.-Q., Yang, F.-Y., Ren, T., & Yuan, L. (2026) · TrAC Trends in Analytical Chemistry · doi:10.1016/j.trac.2026.119081 · Cited by 1 · see citing works

Click Bioconjugation of Aza‐BODIPY Fluorophores to LfcinB Peptides for Improved Biocompatibility

Rodríguez-Mayor, A. V., Morales‐Chamorro, M., Pineda‐Castañeda, H. M., Monroy, Z. J. R., García‐Castañeda, J. E., Farfán, N., & Santillan, R. L. (2026) · European Journal of Organic Chemistry · doi:10.1002/ejoc.70857

Bioapplications of small molecule Aza-BODIPY: from rational structural design to in vivo investigations

Shi, Z., Xu, H., Hu, W., Bai, H., Peng, B., Ji, L., Fan, Q., Li, L., & Huang, W. (2020) · Chemical Society Reviews · doi:10.1039/d0cs00234h · Cited by 474 · see citing works

Near-infrared absorbing (>700 nm) aza-BODIPYs by freezing the rotation of the aryl groups

Wang, Y., Zhang, D., Xiong, K., Shang, R., & Jiang, X. (2021) · Chinese Chemical Letters · doi:10.1016/j.cclet.2021.06.083 · Cited by 36 · see citing works

Near‐Infrared Absorbing Aza‐BODIPY Dyes for Optoelectronic Applications

Pinjari, D., Patil, Y., & Misra, R. (2024) · Chemistry - An Asian Journal · doi:10.1002/asia.202400167 · Cited by 31 · see citing works

Syntheses, optical properties, and bioimaging application of near-infrared aza-BODIPY dyes with electronic push–pull system

Yao, Y., Xiao, X., Liu, S., Tian, B., & Zhang, J. (2023) · Research on Chemical Intermediates · doi:10.1007/s11164-023-05028-0 · Cited by 7 · see citing works

Self‐Assembled (Aza)BODIPY Dyes for Biomedical in Vivo Imaging

Albers, A., Masthoff, M., & Fernández, G. (2026) · Angewandte Chemie International Edition · doi:10.1002/anie.202525491 · Cited by 16 · see citing works