Novel aza-BODIPY based small molecular NIR-II fluorophores for in vivo imaging
Abstract
A new class of small molecular NIR-II fluorophores based on aza-BODIPY with promising photophysical properties (large Stokes shift, superior photostability, good fluorescence brightness), show great potential as NIR-II in vivo imaging agents.
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Aza-BODIPY core-based dyes with strong electron-donating groups in the 3,5-positions present prolonged emission in the SWIR region and high quantum yields (e.g., NJ1060).
“A new series of aza-BODIPY core-based dyes, which present prolonged emission in the SWIR region and high quantum yields, was developed by incorporating strong electron-donating groups in the 3,5-positions of aza-BODIPY (e.g., NJ1060).63”
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- Authors
- Bai, L., Sun, P., Liu, Y., Zhang, H., Hu, W., Zhang, W., Liu, Z., Fan, Q., Li, L., & Huang, W.
- Affiliations
- Nanjing Tech University (CN)
- Nanjing University of Posts and Telecommunications (CN)
- Corresponding author
- Liu, Zhipeng
- Fan, Quli
- Li, Lin
- Venue
- Chemical Communications
- Publisher
- Royal Society of Chemistry (RSC)
- Published
- 2019
- Volume
- 55
- Issue
- 73
- Pages
- 10920-10923
- ISSN
- 1359-7345 (ISSN-L)
- 1364-548X
- OpenAlex
- W2967384131
- Cited by
- 187
- References
- 33
- Citations by year
- 2026: 20 · 2025: 32 · 2024: 23 · 2023: 27 · 2022: 33 · 2021: 32 · 2020: 19 · 2019: 1
- FWCI
- 7.67
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Chemical Communications (publishedVersion)
- PubMed (publishedVersion)
- Funders
- National Natural Science Foundation of China (21501085, 21574064, 21674048, 81672508)
- Natural Science Foundation of Shaanxi Province (2019JM-016)
- Topics
- Physical Sciences › Materials Science › Materials Chemistry › Luminescence and Fluorescent Materials
- Physical Sciences › Chemistry › Spectroscopy › Molecular Sensors and Ion Detection
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Biophysics › Advanced Fluorescence Microscopy Techniques
- Keywords
- NIR-II fluorophores, aza-BODIPY, small-molecule dyes, in vivo imaging, deep tissue imaging, photostability, large Stokes shift, fluorescence quantum yield
- MeSH terms
- Density Functional Theory, Animals, Boron Compounds, Fluorescence, Fluorescent Dyes, Infrared Rays, Models, Chemical, Pyrroles, Drug Design, Poloxamer, Cell Line, Tumor, Mice, Nanoparticles, Optical Imaging
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