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Cited by 141Musculoskeletal pain and rehabilitationPediatric Pain Management TechniquesPain Mechanisms and Treatments

The DOI matches its Crossref record; 161 of the 161 references it cites were found in a registry or an index.

Pain-Related Fear, Pain Intensity and Function in Individuals With Chronic Musculoskeletal Pain: A Systematic Review and Meta-Analysis

Open access
Martinez-Calderon, Javier, Flores-Cortes, Mar, Morales-Asencio, Jose Miguel, Luque-Suarez, Alejandro·2019·The Journal of Pain
DOI 10.1016/j.jpain.2019.04.009
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Abstract

Pain-related fear is considered a strong psychological predictor for both chronic pain and disability. The aims of this study were to systematically review and critically appraise the concurrent association and the predictive value of pain-related fear affecting both pain intensity and disability in individuals with chronic musculoskeletal pain (MSK). PubMed, AMED, CINAHL, PsycINFO, PubPsych, and the grey literature were searched from inception to January 2019. Observational studies reporting cross-sectional and longitudinal associations between pain-related fear and pain intensity and/or disability were included. The GRADE criteria judged whether the overall quality and strength of the evidence was high or low in terms of risk of bias, inconsistency, indirectness, imprecision and publication bias. Seventy observational studies (97% cross-sectional) were included with a total sample of 15,623 individuals (63.56% females) with chronic MSK. Pain-related fear is composed of fear of pain, pain-related anxiety, and fear-avoidance beliefs. Greater levels of fear of pain, pain-related anxiety, and fear-avoidance beliefs were significantly associated with greater pain intensity and disability. However, the quality and strength of the evidence was very low owing to the imprecision of results, risk of bias, indirectness, and publication bias were common across the included studies. Despite these limitations, these findings highlight the potential role that pain-related fear may play in chronic MSK and disability. The field would benefit from research using higher quality studies and longitudinal designs. PERSPECTIVE: This article presents promising results about the concurrent association between pain-related fear and both pain intensity and disability in individuals with chronic MSK. Nevertheless, the overall quality and strength of the evidence was very low in terms of risk of bias, indirectness, imprecision, and publication bias. Thus, the findings should be taken with caution, and further research is needed. PROSPERO: CRD42018082018.

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Crossref · 10.1016/j.jpain.2019.04.009

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Citations

Cites

Research works printed but not linked: 3

  1. Camacho-Soto, 2012, Adults with chronic low back pain, PMRJ, 4, 493
  2. Nieminen, 2013, Standardised regression coefficient as an effect size index in summarising the reported findings between quantitative exposure and response variables in epidemiological studies, Epidemiol Biostat Public Health, 10, e88541
  3. 2015, Stata Statistical Software: Release 14

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Metadata

Authors
Martinez-Calderon, J., Flores-Cortes, M., Morales-Asencio, J. M., & Luque-Suarez, A.
ORCID
Morales-Asencio, Jose Miguel
Venue
The Journal of Pain
Publisher
Elsevier BV
Published
2019-12
Volume
20
Issue
12
Pages
1394-1415
ISSN
1526-5900 (ISSN-L)
DOI
10.1016/j.jpain.2019.04.009
OpenAlex
W2944252725
Cited by
141
References
161
Citations by year
2026: 14 · 2025: 31 · 2024: 21 · 2023: 25 · 2022: 18 · 2021: 15 · 2020: 15 · 2019: 2
FWCI
1.61
Type
journal article
Language
en
Open access
Licence
Locations
  • Journal of Pain (publishedVersion)
  • PubMed (publishedVersion)
Funders
Universidad de Málaga
Topics
  • Health Sciences › Health Professions › Physical Therapy, Sports Therapy and Rehabilitation › Musculoskeletal pain and rehabilitation
  • Health Sciences › Medicine › Pediatrics, Perinatology and Child Health › Pediatric Pain Management Techniques
  • Health Sciences › Medicine › Physiology (medical) › Pain Mechanisms and Treatments
Keywords
fear of pain, chronic musculoskeletal pain, pain intensity, disability, pain-related anxiety, fear-avoidance beliefs
MeSH terms
Fear, Humans, Male, Chronic Pain, Musculoskeletal Pain, Observational Studies as Topic

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