Cited by 71Schizophrenia research and treatmentMental Health and PsychiatryAnxiety, Depression, Psychometrics, Treatment, Cognitive Processes

The interaction of affective with psychotic processes: A test of the effects of worrying on working memory, jumping to conclusions, and anomalies of experience in patients with persecutory delusions

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Freeman, Daniel, Startup, Helen, Dunn, Graham, Černis, Emma, Wingham, Gail, Pugh, Katherine, Cordwell, Jacinta, Kingdon, David·2013·Journal of Psychiatric Research

Abstract

Worry has traditionally been considered in the study of common emotional disorders such as anxiety and depression, but recent studies indicate that worry may be a causal factor in the occurrence and persistence of persecutory delusions. The effect of worry on processes traditionally associated with psychosis has not been tested. The aim of the study was to examine the short-term effects of a bout of worry on three cognitive processes typically considered markers of psychosis: working memory, jumping to conclusions, and anomalous internal experience. Sixty-seven patients with persecutory delusions in the context of a non-affective psychotic disorder were randomised to a worry induction, a worry reduction, or a neutral control condition. They completed tests of the cognitive processes before and after the randomisation condition. The worry induction procedure led to a significant increase in worry. The induction of worry did not affect working memory or jumping to conclusions, but it did increase a range of mild anomalous experiences including feelings of unreality, perceptual alterations, and temporal disintegration. Worry did not affect the occurrence of hallucinations. The study shows that a period of worry causes a range of subtle odd perceptual disturbances that are known to increase the likelihood of delusions. It demonstrates an interaction between affective and psychotic processes in patients with delusions.

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Research works printed but not linked: 3

  1. Maher B.A. Anomalous experience and delusional thinking: the logic of explanations Oltmanns T.F. Maher B.A. Delusional beliefs 1988 Wiley New York 15 33
  2. Mayer J. Allen J. Beauregard K. Mood inductions for four specific moods Journal of Mental Imagery 19 1995 133 150
  3. Southgate L. Does worry make paranoia worse? An investigation of the effects of worry on persecutory ideation 2009 University of London DClinPsy thesis

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Authors
Freeman, D., Startup, H., Dunn, G., Černis, E., Wingham, G., Pugh, K., Cordwell, J., & Kingdon, D.
Affiliations
  • Warneford Hospital (GB)
  • University of Manchester (GB)
  • University of Southampton (GB)
Corresponding author
Freeman, Daniel
Venue
Journal of Psychiatric Research
Publisher
Elsevier BV
Published
2013-12
Volume
47
Issue
12
Pages
1837-1842
ISSN
0022-3956 (ISSN-L)
OpenAlex
W2107840269
Cited by
71
References
67
Citations by year
2026: 19 · 2025: 4 · 2024: 1 · 2023: 2 · 2022: 3 · 2021: 2 · 2020: 5 · 2019: 5 · 2018: 7 · 2017: 6 · 2016: 7 · 2015: 5 · 2014: 5
FWCI
4.02
Type
journal article
Language
en
Open access
Locations
  • Journal of Psychiatric Research (publishedVersion, cc-by)
  • Europe PMC (PubMed Central) (publishedVersion)
  • PubMed Central (publishedVersion, cc-by)
  • PubMed (publishedVersion)
  • Research Explorer (The University of Manchester) (publishedVersion, other-oa)
  • ePrints Soton (University of Southampton) (acceptedVersion)
  • University of Birmingham Research Portal (University of Birmingham) (submittedVersion)
Funders
  • UK Medical Research Council
  • UK NHS National Institute for Health Research
  • UK Medical Research Council Senior Clinical Fellowship
Topics
  • Health Sciences › Medicine › Psychiatry and Mental health › Schizophrenia research and treatment
  • Social Sciences › Arts and Humanities › Philosophy › Mental Health and Psychiatry
  • Social Sciences › Psychology › Experimental and Cognitive Psychology › Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
Keywords
worry, persecutory delusions, working memory, jumping to conclusions, anomalous experiences, emotional processing, psychosis, worry reduction, perceptual disorders, hallucinations, delusion formation
MeSH terms
Adolescent, Adult, Aged, Anxiety, Delusions, Female, Humans, Male, Memory, Short-Term, Middle Aged, Neuropsychological Tests, Psychiatric Status Rating Scales, Psychotic Disorders, Schizophrenia, Schizophrenic Psychology, Young Adult

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