Adaptations to skeletal muscle with endurance exercise training in the acutely fed versus overnight-fasted state

Stannard, Stephen R.; Buckley, Alex J.; Edge, Johann A.; Thompson, Martin W.

doi:10.1016/j.jsams.2010.03.002

Cited by 73Muscle metabolism and nutritionCardiovascular and exercise physiologySports Performance and Training

Adaptations to skeletal muscle with endurance exercise training in the acutely fed versus overnight-fasted state

Stannard, Stephen R., Buckley, Alex J., Edge, Johann A., Thompson, Martin W.·2010·Journal of Science and Medicine in Sport

DOI 10.1016/j.jsams.2010.03.002

Open this paper in CoChat — free account

Abstract

Minimising carbohydrate (CHO) status in the peri-training period may accelerate the training adaptations normally observed. The aim of this study was to compare adaptations to endurance training undertaken in the acutely CHO fed and overnight-fasted states. Eight female and six male untrained, healthy participants: aged 26.6+/-5.8 years (mean+/-SD); height 174.7+/-7.6 cm; weight 75.3+/-11.4 kg; VO(2max) 3.48+/-0.67 l/min; were randomly divided into two training groups and undertook four weeks of five days per week endurance cycle ergometer training in either the overnight-fasted (FAST) or acutely fed (FED) state. FAST training had no effect on RER or plasma glucose, lactate and FFA concentrations during subsequent submaximal exercise. Training-induced changes in Vastus lateralis citrate synthase (CS) and 3-hydroxy-CoA dehydrogenase (HAD) activities were not different between training groups (P=0.655 and 0.549, respectively), but when the effect of gender was considered, men responded better to FAST and women responded better to FED. The FAST group showed a significantly greater training-induced increase in VO(2max) and resting muscle glycogen concentration than FED (P=0.014 and P=0.047 respectively), but there was no gender interaction. In conclusion, these results suggest that (a) meal ingestion prior to daily exercise can modify some of the exercise training-induced adaptations normally seen with endurance training compared to when daily exercise is undertaken in the overnight-fasted state; and (b) the extent of these adaptations in skeletal muscle differ slightly between men and women.

Integrity signals

Registry

Crossref · 10.1016/j.jsams.2010.03.002

Cites

21 of 21 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Claims the paper makes

This paper’s full text isn’t openly available, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

High protein diets (>2.2 g·kg−1·day−1) have not resulted in any adverse effects to bone mineral density or kidney function in healthy women.
“High protein diets (>2.2 g·kg−1·day−1) have not resulted in any adverse effects to bone mineral density or kidney function in healthy women [238,239].”
From International society of sports nutrition position stand: nutritional concerns of the female athlete (2023) · cites this paper as [239]

Methods of Enzymatic Analysis
(1975) · Journal of AOAC INTERNATIONAL · doi:10.1093/jaoac/58.5.1085 · Cited by 20,078 · see citing works
Methods of Enzymatic Analysis
(1974) · Elsevier eBooks · doi:10.1016/b978-0-12-091304-6.x5001-0 · Cited by 6,786 · see citing works
Position of the American Dietetic Association, Dietitians of Canada, and the American College of Sports Medicine: Nutrition and Athletic Performance
(2009) · Journal of the American Dietetic Association · doi:10.1016/j.jada.2009.01.005 · Cited by 912 · see citing works
Influence of endurance exercise training and sex on intramyocellular lipid and mitochondrial ultrastructure, substrate use, and mitochondrial enzyme activity
Tarnopolsky, M. A., Rennie, C. D., Robertshaw, H. A., Fedak-Tarnopolsky, S. N., Devries, M. C., & Hamadeh, M. J. (2007) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.00472.2006 · Cited by 457 · see citing works
ISSN exercise & sport nutrition review: research & recommendations
Kreider, R. B., Wilborn, C. D., Taylor, L., Campbell, B., Almada, A. L., Collins, R., Cooke, M., Earnest, C. P., Greenwood, M., Kalman, D. S., et al. (2010) · Journal of the International Society of Sports Nutrition · doi:10.1186/1550-2783-7-7 · Cited by 428 · see citing works
Skeletal muscle adaptation: training twice every second day vs. training once daily
Hansen, A. K., Fischer, C. P., Plomgaard, P., Andersen, J. L., Saltin, B., & Pedersen, B. K. (2005) · Journal of Applied Physiology · doi:10.1152/japplphysiol.00163.2004 · Cited by 286 · see citing works
Carbohydrate loading and metabolism during exercise in men and women
Tarnopolsky, M. A., Atkinson, S. A., Phillips, S. M., & MacDougall, J. D. (1995) · Journal of Applied Physiology · doi:10.1152/jappl.1995.78.4.1360 · Cited by 275 · see citing works
Mitochondrial enzymes increase in muscle in response to 7-10 days of cycle exercise
Spina, R. J., Chi, M. M., Hopkins, M., Nemeth, P. M., Lowry, O. H., & Holloszy, J. O. (1996) · Journal of Applied Physiology · doi:10.1152/jappl.1996.80.6.2250 · Cited by 247 · see citing works
Higher skeletal muscle α<sub>2</sub>AMPK activation and lower energy charge and fat oxidation in men than in women during submaximal exercise
Roepstorff, C., Thiele, M., Hillig, T., Pilegaard, H., Richter, E. A., Wojtaszewski, J. F. P., & Kiens, B. (2006) · The Journal of Physiology · doi:10.1113/jphysiol.2006.108720 · Cited by 238 · see citing works
Influence of pre‐exercise muscle glycogen content on exercise‐induced transcriptional regulation of metabolic genes
Pilegaard, H., Keller, C., Steensberg, A., Wulff Helge, J., Klarlund Pedersen, B., Saltin, B., & Neufer, P. D. (2002) · The Journal of Physiology · doi:10.1113/jphysiol.2002.016832 · Cited by 234 · see citing works
Effect of gender on lipid kinetics during endurance exercise of moderate intensity in untrained subjects
Mittendorfer, B., Horowitz, J. F., & Klein, S. (2002) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.00504.2001 · Cited by 154 · see citing works
Substrate availability and transcriptional regulation of metabolic genes in human skeletal muscle during recovery from exercise
Pilegaard, H., Osada, T., Andersen, L. T., Helge, J. W., Saltin, B., & Neufer, P. D. (2005) · Metabolism · doi:10.1016/j.metabol.2005.03.008 · Cited by 154 · see citing works
Promoting training adaptations through nutritional interventions
Hawley, J. A., Tipton, K. D., & Millard-Stafford, M. L. (2006) · Journal of Sports Sciences · doi:10.1080/02640410500482727 · Cited by 149 · see citing works
Position of the American Dietetic Association, Dietitians of Canada, and the American College of Sports Medicine
(2000) · Journal of the American Dietetic Association · doi:10.1016/s0002-8223(00)00428-4 · Cited by 148 · see citing works
Effect of training in the fasted state on metabolic responses during exercise with carbohydrate intake
De Bock, K., Derave, W., Eijnde, B. O., Hesselink, M. K., Koninckx, E., Rose, A. J., Schrauwen, P., Bonen, A., Richter, E. A., & Hespel, P. (2008) · Journal of Applied Physiology · doi:10.1152/japplphysiol.01195.2007 · Cited by 144 · see citing works
Effect of dietary fat on metabolic adjustments to maximal &OV0312;O2 and endurance in runners
Muoio, D. M., Leddy, J. J., Horvath, P. J., AW, A. B., & Pendergast, D. R. (1994) · Medicine & Science in Sports & Exercise · doi:10.1249/00005768-199401000-00014 · Cited by 125 · see citing works
Sex differences in hormone-sensitive lipase expression, activity, and phosphorylation in skeletal muscle at rest and during exercise
Roepstorff, C., Donsmark, M., Thiele, M., Vistisen, B., Stewart, G., Vissing, K., Schjerling, P., Hardie, D. G., Galbo, H., & Kiens, B. (2006) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.00097.2006 · Cited by 118 · see citing works
Effect of a divided caffeine dose on endurance cycling performance, postexercise urinary caffeine concentration, and plasma paraxanthine
Conway, K. J., Orr, R., & Stannard, S. R. (2003) · Journal of Applied Physiology · doi:10.1152/japplphysiol.00911.2002 · Cited by 103 · see citing works
Self-citation
Effect of low-carbohydrate-ketogenic diet on metabolic and hormonal responses to graded exercise in men.
Langfort, J., Pilis, W., Zarzeczny, R., Nazar, K., & Kaciuba-Uściłko, H. (1996) · PubMed · Cited by 64 · see citing works
Impact of carbohydrate supplementation during endurance training on glycogen storage and performance
Nybo, L., Pedersen, K., Christensen, B., Aagaard, P., Brandt, N., & Kiens, B. (2009) · Acta Physiologica · doi:10.1111/j.1748-1716.2009.01996.x · Cited by 58 · see citing works
ISSN Exercise & Sport Nutrition Review: Research & Recommendations
Kreider, R. B., Almada, A. L., Antonio, J., Broeder, C., Earnest, C., Greenwood, M., Incledon, T., Kalman, D. S., Kleiner, S. M., Leutholtz, B., et al. (2004) · Journal of the International Society of Sports Nutrition · doi:10.1186/1550-2783-1-1-1 · Cited by 38 · see citing works

Flagged first, then by citations

Sorted by citations

Training-Induced Changes in Mitochondrial Content and Respiratory Function in Human Skeletal Muscle
Granata, C., Jamnick, N. A., & Bishop, D. J. (2018) · Sports Medicine · doi:10.1007/s40279-018-0936-y · Cited by 247 · see citing works
Interval training in the fed or fasted state improves body composition and muscle oxidative capacity in overweight women: Interval Training Improves Body Composition
Gillen, J. B., Percival, M. E., Ludzki, A., Tarnopolsky, M. A., & Gibala, M. J. (2013) · Obesity · doi:10.1002/oby.20379 · Cited by 222 · see citing works
Beneficial metabolic adaptations due to endurance exercise training in the fasted state
Van Proeyen, K., Szlufcik, K., Nielens, H., Ramaekers, M., & Hespel, P. (2011) · Journal of Applied Physiology · doi:10.1152/japplphysiol.00907.2010 · Cited by 196 · see citing works
Breakfast and exercise contingently affect postprandial metabolism and energy balance in physically active males
Gonzalez, J. T., Veasey, R. C., Rumbold, P. L. S., & Stevenson, E. J. (2013) · British Journal of Nutrition · doi:10.1017/s0007114512005582 · Cited by 108 · see citing works
Training in the fasted state improves glucose tolerance during fat-rich diet
Proeyen, K. V., Szlufcik, K., Nielens, H., Pelgrim, K., Deldicque, L., Hesselink, M. K. C., Veldhoven, P. P. V., & Hespel, P. (2010) · The Journal of Physiology · doi:10.1113/jphysiol.2010.196493 · Cited by 106 · see citing works
The relationship between skeletal muscle mitochondrial citrate synthase activity and whole body oxygen uptake adaptations in response to exercise training.
Vigelsø, A., Andersen, N. B., & Dela, F. (2014) · Europe PMC (PubMed Central) · Cited by 96 · see citing works
Exercise Training and Fasting: Current Insights
Zouhal, H., Saeidi, A., Salhi, A., Li, H., Essop, M. F., Laher, I., Rhibi, F., Amani-Shalamzari, S., & Abderrahman, A. B. (2020) · Open Access Journal of Sports Medicine · doi:10.2147/oajsm.s224919 · Cited by 97 · see citing works
International society of sports nutrition position stand: nutritional concerns of the female athlete
Sims, S. T., Kerksick, C. M., Smith-Ryan, A. E., Janse de Jonge, X. A. K., Hirsch, K. R., Arent, S. M., Hewlings, S. J., Kleiner, S. M., Bustillo, E., Tartar, J. L., et al. (2023) · Journal of the International Society of Sports Nutrition · doi:10.1080/15502783.2023.2204066 · Cited by 91 · see citing works
“exercising in a fasted state can blunt fat oxidation [240], whereas exercising in a fed state will result in a greater total daily energy expenditure and increased fat oxidation, potentially improving body composition [134,135].”
Background
Is breakfast the most important meal of the day?
Betts, J. A., Chowdhury, E. A., Gonzalez, J. T., Richardson, J. D., Tsintzas, K., & Thompson, D. (2016) · Proceedings of The Nutrition Society · doi:10.1017/s0029665116000318 · Cited by 83 · see citing works
Effects of Intermittent Fasting on Specific Exercise Performance Outcomes: A Systematic Review Including Meta-Analysis
Correia, J. M., Santos, I., Pezarat‐Correia, P., Minderico, C. S., & Mendonça, G. V. (2020) · Nutrients · doi:10.3390/nu12051390 · Cited by 70 · see citing works
What Should I Eat before Exercise? Pre-Exercise Nutrition and the Response to Endurance Exercise: Current Prospective and Future Directions
Rothschild, J. A., Kilding, A. E., & Plews, D. J. (2020) · Nutrients · doi:10.3390/nu12113473 · Cited by 67 · see citing works
Direct and indirect lactate oxidation in trained and untrained men
Emhoff, C.-A. W., Messonnier, L. A., Horning, M. A., Fattor, J. A., Carlson, T. J., & Brooks, G. A. (2013) · Journal of Applied Physiology · doi:10.1152/japplphysiol.00538.2013 · Cited by 62 · see citing works
Carbohydrate Restriction in Type 1 Diabetes: A Realistic Therapy for Improved Glycaemic Control and Athletic Performance?
Scott, S. N., Anderson, L., Morton, J. P., Wagenmakers, A. J. M., & Riddell, M. C. (2019) · Nutrients · doi:10.3390/nu11051022 · Cited by 60 · see citing works
Effect of fed- versus fasted state resistance training during Ramadan on body composition and selected metabolic parameters in bodybuilders
Trabelsi, K., Stannard, S. R., Ghlissi, Z., Maughan, R. J., Kallel, C., Jamoussi, K., Zeghal, K. M., & Hakim, A. (2013) · Journal of the International Society of Sports Nutrition · doi:10.1186/1550-2783-10-23 · Cited by 60 · see citing works
Self-citation
Exercising your fat (metabolism) into shape: a muscle-centred view
Gemmink, A., Schrauwen, P., & Hesselink, M. K. C. (2020) · Diabetologia · doi:10.1007/s00125-020-05170-z · Cited by 59 · see citing works
Supplements and Nutritional Interventions to Augment High-Intensity Interval Training Physiological and Performance Adaptations—A Narrative Review
Forbes, S. C., Candow, D. G., Smith‐Ryan, A. E., Hirsch, K. R., Roberts, M. D., VanDusseldorp, T. A., Stratton, M. T., Kaviani, M., & Little, J. P. (2020) · Nutrients · doi:10.3390/nu12020390 · Cited by 60 · see citing works
Concomitant Effects of Ramadan Fasting and Time-Of-Day on Apolipoprotein AI, B, Lp-a and Homocysteine Responses during Aerobic Exercise in Tunisian Soccer Players
Hammouda, O., Chtourou, H., Aloui, A., Chahed, H., Kallel, C., Miled, A., Chamari, K., Chaouachi, A., & Souissi, N. (2013) · PLoS ONE · doi:10.1371/journal.pone.0079873 · Cited by 55 · see citing works
Impact of Endurance Exercise Training in the Fasted State on Muscle Biochemistry and Metabolism in Healthy Subjects: Can These Effects be of Particular Clinical Benefit to Type 2 Diabetes Mellitus and Insulin-Resistant Patients?
Hansen, D., Strijcker, D. D., & Calders, P. (2016) · Sports Medicine · doi:10.1007/s40279-016-0594-x · Cited by 53 · see citing works
Effects of Fed- Versus Fasted-State Aerobic Training During Ramadan on Body Composition and Some Metabolic Parameters in Physically Active Men
Trabelsi, K., Abed, K. E., Stannard, S. R., Jammoussi, K., Zeghal, K. M., & Hakim, A. (2012) · International Journal of Sport Nutrition and Exercise Metabolism · doi:10.1123/ijsnem.22.1.11 · Cited by 49 · see citing works
Self-citation
Effects of Ramadan Fasting on Health and Athletic Performance
Chtourou, H. (2015) · OMICS International eBooks · doi:10.4172/978-1-63278-030-0-031 · Cited by 30 · see citing works
Exercise-nutrient interactions for improved postprandial glycemic control and insulin sensitivity
Gillen, J. B., Estafanos, S., & Govette, A. (2021) · Applied Physiology, Nutrition, and Metabolism · doi:10.1139/apnm-2021-0168 · Cited by 44 · see citing works
Postexercise skeletal muscle signaling responses to moderate- to high-intensity steady-state exercise in the fed or fasted state
Stocks, B., Dent, J. R., Ogden, H. B., Zemp, M., & Philp, A. (2018) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.00311.2018 · Cited by 38 · see citing works
Low-carbohydrate diets: Effects on metabolism and exercise – A comprehensive literature review
Macedo, R. C. O., Santos, H. O., Tinsley, G. M., & Reischak-Oliveira, Á. (2020) · Clinical Nutrition ESPEN · doi:10.1016/j.clnesp.2020.07.022 · Cited by 38 · see citing works
Effects of post-absorptive and postprandial exercise on 24 h fat oxidation
Shimada, K., Yamamoto, Y., Iwayama, K., Nakamura, K., Yamaguchi, S., Hibi, M., Nabekura, Y., & Tokuyama, K. (2013) · Metabolism · doi:10.1016/j.metabol.2012.12.008 · Cited by 33 · see citing works
Exercise before breakfast increases 24-h fat oxidation in female subjects
Iwayama, K., Kawabuchi, R., Nabekura, Y., Kurihara, R., Park, I., Kobayashi, M., Ogata, H., Kayaba, M., Omi, N., Satoh, M., et al. (2017) · PLoS ONE · doi:10.1371/journal.pone.0180472 · Cited by 32 · see citing works
Protein Nutrition for Endurance Athletes: A Metabolic Focus on Promoting Recovery and Training Adaptation
Witard, O. C., Hearris, M. A., & Morgan, P. T. (2025) · Sports Medicine · doi:10.1007/s40279-025-02203-8 · Cited by 34 · see citing works
Does Ramadan fasting affect the diurnal variations in metabolic responses and total antioxidant capacity during exercise in young soccer players?
Hammouda, O., Chtourou, H., Aloui, A., Mejri, M. A., Chahed, H., Miled, A., Chamari, K., Chaouachi, A., & Souissi, N. (2014) · Sport Sciences for Health · doi:10.1007/s11332-014-0179-8 · Cited by 29 · see citing works
Prevalence and Determinants of Fasted Training in Endurance Athletes: A Survey Analysis
Rothschild, J. A., Kilding, A. E., & Plews, D. J. (2020) · International Journal of Sport Nutrition and Exercise Metabolism · doi:10.1123/ijsnem.2020-0109 · Cited by 26 · see citing works
Carbohydrate mouth rinsing has no effect on power output during cycling in a glycogen-reduced state
Ali, A., Yoo, M. J. Y., Moss, C., & Breier, B. H. (2016) · Journal of the International Society of Sports Nutrition · doi:10.1186/s12970-016-0131-1 · Cited by 23 · see citing works
Overnight fasting compromises exercise intensity and volume during sprint interval training but improves high-intensity aerobic endurance
Terada, T., Eshghi, S. R. T., Liubaoerjijin, Y., Kennedy, M. D., Myette‐Côté, É., Fletcher, K., & Boulé, N. G. (2019) · The Journal of Sports Medicine and Physical Fitness · doi:10.23736/s0022-4707.18.08281-6 · Cited by 21 · see citing works
Divergent serum metabolomic, skeletal muscle signaling, transcriptomic, and performance adaptations to fasted versus whey protein-fed sprint interval training
Aird, T. P., Farquharson, A. J., Bermingham, K. M., O’Sullivan, A. M., Drew, J. E., & Carson, B. P. (2021) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.00265.2021 · Cited by 21 · see citing works
Female Athlete Representation and Dietary Control Methods Among Studies Assessing Chronic Carbohydrate Approaches to Support Training
Kuikman, M. A., McKay, A. K. A., Smith, E. S., Ackerman, K. E., Harris, R., Elliott-Sale, K. J., Stellingwerff, T., & Burke, L. M. (2023) · International Journal of Sport Nutrition and Exercise Metabolism · doi:10.1123/ijsnem.2022-0214 · Cited by 19 · see citing works
Effects of exercising before breakfast on the health of T2DM patients—A randomized controlled trial
Brinkmann, C. K., Weh‐Gray, O., Brixius, K., Bloch, W., Predel, H., & Kreutz, T. (2019) · Scandinavian Journal of Medicine and Science in Sports · doi:10.1111/sms.13543 · Cited by 19 · see citing works
ENDURANCE TRAINING IN FASTING CONDITIONS: BIOLOGICAL ADAPTATIONS AND BODY WEIGHT MANAGEMENT.
Vicente-Salar, N., Otegui, A. U., & Roche, E. (2015) · PubMed · doi:10.3305/nh.2015.32.6.9488 · Cited by 18 · see citing works
Metabolic adaptations to endurance training and nutrition strategies influencing performance
Earnest, C. P., Rothschild, J. A., Harnish, C., & Naderi, A. (2018) · Research in Sports Medicine · doi:10.1080/15438627.2018.1544134 · Cited by 17 · see citing works
The effect of carbohydrate mouth rinse on performance, biochemical and psychophysiological variables during a cycling time trial: a crossover randomized trial
Ferreira, A. M., Farias-Junior, L. F., Mota, T. A. A., Elsangedy, H. M., Marcadenti, A., Lemos, T. M. A. M., Okano, A. H., & Fayh, A. P. T. (2018) · Journal of the International Society of Sports Nutrition · doi:10.1186/s12970-018-0225-z · Cited by 15 · see citing works
Ramadan and Its Effect on Fuel Selection during Exercise and Following Exercise Training
Stannard, S. R. (2011) · Asian Journal of Sports Medicine · doi:10.5812/asjsm.34760 · Cited by 15 · see citing works
Self-citation
Menstrual Cycle Tracking in Sports Research: Challenges, Progress, and Future Directions
Dole, A., Beaven, C. M., & Sims, S. T. (2023) · Physiologia · doi:10.3390/physiologia3040044 · Cited by 14 · see citing works
Walking Football During Ramadan Fasting for Cardiometabolic and Psychological Health Benefits to the Physically Challenged and Aged Populations
Zainudin, S. B., Salle, D. D. A., & Aziz, A. R. (2022) · Frontiers in Nutrition · doi:10.3389/fnut.2021.779863 · Cited by 12 · see citing works
Acute metabolic response to fasted and postprandial exercise
de Lima, F. D., Correia, A. L. M., Teixeira, D. S., Neto, D. V. D. S., Fernandes, Í. S. G., Viana, M. B. X., Petitto, M., Sampaio, R. A. D. S., Chaves, S. N., Alves, S. T., et al. (2015) · International Journal of General Medicine · doi:10.2147/ijgm.s87429 · Cited by 12 · see citing works
Effects of Prior Fasting on Fat Oxidation during Resistance Exercise
Frawley, K., Greenwald, G., Rogers, R. R., Petrella, J. K., & Marshall, M. R. (2018) · International journal of exercise science · doi:10.70252/cqmf3722 · Cited by 11 · see citing works
Losing, Gaining and Making Weight for Athletes
O'Connor, H. T., & Slater, G. (2011) · Wiley eBooks · doi:10.1002/9781444344905.ch17 · Cited by 10 · see citing works
Exploring the Effects of Energy Constraints on Performance, Body Composition, Endocrinological/Hematological Biomarkers, and Immune System among Athletes: An Overview of the Fasting State
Nobarı, H., Saedmocheshi, S., Murawska‐Ciałowicz, E., Clemente, F. M., Suzuki, K., & Silva, A. F. (2022) · Nutrients · doi:10.3390/nu14153197 · Cited by 9 · see citing works
Dietary Manipulations Concurrent to Endurance Training
Rothschild, J. A., & Earnest, C. P. (2018) · Journal of Functional Morphology and Kinesiology · doi:10.3390/jfmk3030041 · Cited by 8 · see citing works
The effect of preprandial versus postprandial physical activity on glycaemia: Meta-analysis of human intervention studies
Slebe, R., Wenker, E., Schoonmade, L. J., Bouman, E. J., Blondin, D. P., Campbell, D. J. T., Carpentier, A. C., Joris Hoeks, J., Raina, P. S., Schrauwen, P., et al. (2024) · Diabetes Research and Clinical Practice · doi:10.1016/j.diabres.2024.111638 · Cited by 8 · see citing works
Chronic carbohydrate restriction improves endurance capacity and body composition in men and women
O'Connor, W., O'Connor, E., Barnes, M. J., Miller, M. W., Gardener, H., & Stannard, S. R. (2022) · Journal Of Science & Cycling · doi:10.28985/1322.jsc.04 · Cited by 5 · see citing works
Self-citation
Comparison of physiological and clinical markers for chronic sprint-interval training exercise performed either in the fasted or fed states among healthy adults
Tan, V., Lim, I., Tan, P. T., Tan, F. H. Y., & Aziz, A. R. (2021) · Current Research in Physiology · doi:10.1016/j.crphys.2021.09.003 · Cited by 5 · see citing works
Consensus Document of the Spanish Nutrition Society (SEÑ) on Nutritional Strategies in Sports
Mielgo‐Ayuso, J., Macho‐González, A., Úbeda, N., Sánchez-Oliver, A. J., Martínez‐Ferrán, M., Fernández‐Lázaro, D., Aparicio‐Ugarriza, R., Roche, E., & González‐Gross, M. (2025) · Nutrients · doi:10.3390/nu17243862 · Cited by 4 · see citing works
Restricting Carbohydrates in the Diet-A Possible Method of Meeting the Challenges of Increasing Diabesity in Type1 Diabetes along with Meeting Exercise Performances Requirements-A Review
Kaur, K. K. (2019) · Open Access Journal of Endocrinology · doi:10.23880/oaje-16000138 · Cited by 2 · see citing works
Acute Glucose Tolerance in Response to Lower- and Higher-Load Resistance Exercise in Postmenopausal Women: Contribution of Aerobic Capacity and Body Composition
Paquin, J., St‐Martin, P., Lord, S.-È., Gendron, P., Brochu, M., & Dionne, I. J. (2025) · The Journal of Strength and Conditioning Research · doi:10.1519/jsc.0000000000005096 · Cited by 2 · see citing works
Effets de l’entraînement à jeun sur la V˙O2max , l’oxydation des lipides et la performance aérobie chez des jeunes hommes modérément entraînés
Charlot, K., Pichon, A., & Chapelot, D. (2016) · Science & Sports · doi:10.1016/j.scispo.2016.03.002 · Cited by 2 · see citing works
Exercise responses and training during daytime fasting in the month of Ramadan and its impact on training-induced adaptations Author
Damit, N. F., Lim, V. T. W., Muhamed, A. M. C., Chaouachi, A., Chamari, K., Singh, R., Chia, M., & Aziz, A. R. (2014) · Cited by 2 · see citing works
exercise training in the fasted state Beneficial metabolic adaptations due to endurance
Hespel, P., Proeyen, K. V., Szlufcik, K., Nielens, H., & Ramaekers, M. (2011) · Cited by 2 · see citing works
Fat Metabolism During Exercise and Dietary Interventions for Enhancing Fat Metabolism and Athletic Performance
Cornish, S. M., McBreairty, L. E., Chilibeck, P. D., & Zello, G. A. (2016) · Elsevier eBooks · doi:10.1016/b978-1-63067-036-8.00018-4 · Cited by 2 · see citing works
Exploring the Intersection of Bodybuilding and Ramadan: Strategies for Maintaining Muscle Mass and Performance During Fasting
Hamlaoui, K. (2024) · Journal of Orthopaedic Science and Research · doi:10.46889/josr.2024.5110 · Cited by 1 · see citing works
Fasted Sprint Interval Training Results in Some Beneficial Skeletal Muscle Metabolic, but Similar Metabolomic and Performance Adaptations Compared With Carbohydrate-Fed Training in Recreationally Active Male
Aird, T. P., Farquharson, A. J., Bermingham, K. M., O’Sullivan, A. M., Drew, J. E., & Carson, B. P. (2022) · International Journal of Sport Nutrition and Exercise Metabolism · doi:10.1123/ijsnem.2022-0142 · Cited by 1 · see citing works
Effects of exercise on tests measuring attention and executive function in younger and older adults
Burda, A. N., Baldwin, J. B. J., Cravatta, J., Heetland, J., Jacobs, K. J. K., Merfeld, H., Rausch, J., Rinnels, M., & Zollman, R. (2021) · Clinical Archives of Communication Disorders · doi:10.21849/cacd.2021.00360 · Cited by 1 · see citing works
Efeitos do jejum intermitente na composição corporal e no rendimento físico
Correia, J. M., Pezarat‐Correia, P., & Mendonça, G. V. (2021) · Acta Portuguesa de Nutrição · doi:10.21011/apn.2021.2706
The Overweight Athlete
O'Connor, H. T. (2013) · Wiley eBooks · doi:10.1002/9781118692318.ch41 · Cited by 1 · see citing works
Regulation of Glycemia and Energy Substrate Partitioning in Exercising Humans
Emhoff, C. W. (2013) · eScholarship (California Digital Library) · Cited by 1 · see citing works
A Comparison between the effects of a Whey Protein Drink and Trim Milk on Rehydration after Exercise in the Heat.
Robinson, C. J. (2013) · Otago University Research Archive (University of Otago)
MANIPULATION OF TRAINING STIMULUS AND NUTRITIONAL SUPPORT
James, A., & Cochran, R. C. (2013)
Effects of carbohydrate restriction on exercise performance
Shiose, K. (2017) · 体力科學 · doi:10.7600/jspfsm.66.125
Nutritional regulation of mitochondrial biogenic energy-sensing pathways in skeletal muscle following endurance exercise
Stocks, B. (2019) · University of Birmingham Institutional Research Archive (University of Birmingham)
Peri-exercise nutrition: an innovative approach to dietary assessment in trained populations
Kozior, M. (2020) · Arrow@dit (Dublin Institute of Technology) · doi:10.34961/6072
Evidence-Based Nutritional Strategies to Enhance Athletic Performance
Schroeder, N. (2021) · Strength and conditioning journal · doi:10.1519/ssc.0000000000000642
New possibilities for exercise in type 2 diabetics with coronary artery disease - aerobic exercise in the fasted state (Preprint)Preprint
Ardérius, M., Gómez, N., Alves, M., Rodrigues, A. L., Arderius, C., Pinto, R., Angarten, V. G., Rodrigues, J. M., & Jordão, A. (2019) · doi:10.2196/preprints.13443
Efectos agudos del ejercicio aeróbico en estado de ayuno sobre el metabolismo y utilización de carbohidratos y grasas en adultos sedentarios con sobrepeso y obesidad: Un estudio piloto
Morán, M., & Peñailillo, L. (2022) · Revista chilena de nutrición · doi:10.4067/s0717-75182022000300333
Cardio em Jejum
Borges, D. S. (2022) · Ciencia Latina Revista Científica Multidisciplinar · doi:10.37811/cl_rcm.v6i4.2794
İDMANDAN ƏVVƏL VƏ SONRA QİDALANMANIN ORQANİZMƏ TƏSİRİ
İbrahimli, I. H., Yusifov, G. D., Rustamli, A. M., & Talibov, M. D. (2020) · Scientific News of Academy of Physical Education and Sport · doi:10.28942/snsa.v2i4y2020.729
Cardio em Jejum
Borges, D. S. (2022) · Journal · doi:10.56238/cpahjournalv5n2-014
Effects of intermittent fasting and sports performance: a narrative review
Matas, S., Pejenaute-Larráyoz, D., & Corbi, F. (2024) · Nutrición Hospitalaria · doi:10.20960/nh.05415
Affective responses during 8 weeks of fasted or fed moderate aerobic exercise—a randomized controlled trial
Hofstätter, F., Niedermeier, M., Rausch, L. K., Lawley, J. S., & Kopp, M. (2025) · Cogent Psychology · doi:10.1080/23311908.2025.2492448

Effect of training in the fasted state on metabolic responses during exercise with carbohydrate intake
De Bock, K., Derave, W., Eijnde, B. O., Hesselink, M. K., Koninckx, E., Rose, A. J., Schrauwen, P., Bonen, A., Richter, E. A., & Hespel, P. (2008) · Journal of Applied Physiology · doi:10.1152/japplphysiol.01195.2007 · Cited by 144 · see citing works
Beneficial metabolic adaptations due to endurance exercise training in the fasted state
Van Proeyen, K., Szlufcik, K., Nielens, H., Ramaekers, M., & Hespel, P. (2011) · Journal of Applied Physiology · doi:10.1152/japplphysiol.00907.2010 · Cited by 196 · see citing works
Effects of sleeping with reduced carbohydrate availability on acute training responses
Lane, S. C., Camera, D. M., Lassiter, D. G., Areta, J. L., Bird, S. R., Yeo, W. K., Jeacocke, N. A., Krook, A., Zierath, J. R., Burke, L. M., et al. (2015) · Journal of Applied Physiology · doi:10.1152/japplphysiol.00857.2014 · Cited by 102 · see citing works
Glucose ingestion during endurance training does not alter adaptation
van Hall, G., & Pedersen, B. K. (2009)
Interaction of training and diet on metabolism and endurance during exercise in man.
Helge, J. W., Richter, E. A., & Kiens, B. (1996) · The Journal of Physiology · doi:10.1113/jphysiol.1996.sp021309 · Cited by 175 · see citing works

Authors: Stannard, S. R., Buckley, A. J., Edge, J. A., & Thompson, M. W.
Affiliations: The University of Sydney (AU)
University of Auckland (NZ)
Corresponding author: Stannard, Stephen R.
ORCID: Stannard, Stephen R.
Venue: Journal of Science and Medicine in Sport
Publisher: Elsevier BV
Published: 2010-07
Volume: 13
Issue: 4
Pages: 465-469
ISSN: 1440-2440 (ISSN-L)
DOI: 10.1016/j.jsams.2010.03.002
OpenAlex: W1996854572
Cited by: 73
References: 21
Citations by year: 2025: 4 · 2024: 3 · 2023: 3 · 2022: 7 · 2021: 6 · 2020: 9 · 2019: 6 · 2018: 6 · 2017: 2 · 2016: 5 · 2015: 3 · 2014: 3 · 2013: 10 · 2012: 1
FWCI: 2.24
Type: journal article
Language: en
Open access: closed
Licence: www.elsevier.com/tdm/userlicense/1.0/ (tdm)
Locations: Journal of science and medicine in sport (publishedVersion)
PubMed (publishedVersion)
Topics: Life Sciences › Biochemistry, Genetics and Molecular Biology › Cell Biology › Muscle metabolism and nutrition
Health Sciences › Medicine › Complementary and alternative medicine › Cardiovascular and exercise physiology
Health Sciences › Medicine › Orthopedics and Sports Medicine › Sports Performance and Training
Keywords: endurance training, skeletal muscle adaptation, overnight fasting, carbohydrate status, citrate synthase, muscle glycogen, VO2max, sex differences, vastus lateralis, fat oxidation, plasma lactate, plasma glucose, plasma free fatty acids
MeSH terms: Adaptation, Physiological, Adult, Citrate (si)-Synthase, Fasting, Female, Glycogen, Humans, Male, Oxygen Consumption, Physical Endurance, Muscle, Skeletal, Young Adult

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Adaptations to skeletal muscle with endurance exercise training in the acutely fed versus overnight-fasted state

Abstract

Integrity signals

Claims the paper makes

Claims other papers make about this one

Cites

Cited by

Related

Record

About these checks