Inactivation by UDP-glucuronosyltransferase enzymes: The end of androgen signaling

Pharmacogenomics: Translating Functional Genomics into Rational Therapeutics

Evans, W. E., & Relling, M. V. (1999) · Science · doi:10.1126/science.286.5439.487 · Cited by 2,491 · see citing works

Androgen Receptor in Prostate Cancer

Heinlein, C. A., & Chang, C. (2004) · Endocrine Reviews · doi:10.1210/er.2002-0032 · Cited by 1,780 · see citing works

The UDP glycosyltransferase gene superfamily: recommended nomenclature update based on evolutionary divergence

Mackenzie, P. I., Owens, I. S., Burchell, B., Bock, K. W., Bairoch, A., Bélanger, A., Fournel‐Gigleux, S., Green, M. D., Hum, D. W., Iyanagi, T., et al. (1997) · Pharmacogenetics · doi:10.1097/00008571-199708000-00001 · Cited by 1,185 · see citing works

Nomenclature update for the mammalian UDP glycosyltransferase (UGT) gene superfamily

Mackenzie, P. I., Walter Bock, K., Burchell, B., Guillemette, C., Ikushiro, S.-I., Iyanagi, T., Miners, J. O., Owens, I. S., & Nebert, D. W. (2005) · Pharmacogenetics and Genomics · doi:10.1097/01.fpc.0000173483.13689.56 · Cited by 821 · see citing works

Glucuronidation of Drugs and Other Compounds

Dutton, G. J. (2019) · Chapman & Hall/CRC eBooks · doi:10.1201/9780429264177 · Cited by 804 · see citing works

STRUCTURAL AND FUNCTIONAL STUDIES OF UDP-GLUCURONOSYLTRANSFERASES*

Radominska-p, A., Czernik, P. J., Little, J. M., Battaglia, E., & Mackenzie, P. I. (1999) · Drug Metabolism Reviews · doi:10.1081/dmr-100101944 · Cited by 497 · see citing works

Changes in serum concentrations of conjugated and unconjugated steroids in 40- to 80-year-old men

Bèlanger, A., Candas, B., Dupont, A., Cusan, L., Diamond, P., Gomez, J.-L., & Labrie, F. (1994) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.79.4.7962278 · Cited by 437 · see citing works

UDP-Glucuronosyltransferases

King, C., Rios, G. R., Green, M. D., & Tephly, T. R. (2000) · Current Drug Metabolism · doi:10.2174/1389200003339171 · Cited by 432 · see citing works

DHEA and its transformation into androgens and estrogens in peripheral target tissues: Intracrinology

Labrie, F., Luu-The, V., Labrie, C., & Simard, J. (2001) · Frontiers in Neuroendocrinology · doi:10.1006/frne.2001.0216 · Cited by 366 · see citing works

Relative Enzymatic Activity, Protein Stability, and Tissue Distribution of Human Steroid-Metabolizing UGT2B Subfamily Members**This work was supported by the Medical Research Council of Canada, the Fonds de la Recherche en Sante du Quebec, and Endorecherche.

Turgeon, D., Carrier, J.-S., Lévesque, E., Hum, D. W., & Bélanger, A. (2001) · Endocrinology · doi:10.1210/endo.142.2.7958 · Cited by 333 · see citing works

Large Differences in Testosterone Excretion in Korean and Swedish Men Are Strongly Associated with a UDP-Glucuronosyl Transferase 2B17 Polymorphism

Jakobsson, J., Ekström, L., Inotsume, N., Garle, M., Lorentzon, M., Ohlsson, C., Roh, H., Carlström, K., & Rane, A. (2006) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2005-1643 · Cited by 282 · see citing works

Cutaneous androgen metabolism: basic research and clinical perspectives

Chen, W., Thiboutot, D., & Zouboulis, C. C. (2002) · Journal of Investigative Dermatology · doi:10.1046/j.1523-1747.2002.00613.x · Cited by 273 · see citing works

Thirteen UDPglucuronosyltransferase genes are encoded at the human UGT1 gene complex locus

Gong, Q.-H., Cho, J. W., Huang, T., Potter, C., Gholami, N., Basu, N. K., Kubota, S., Carvalho, S., Pennington, M. W., Owens, I. S., et al. (2001) · Pharmacogenetics · doi:10.1097/00008571-200106000-00011 · Cited by 271 · see citing works

Glucuronidation of amines and other xenobiotics catalyzed by expressed human UDP-glucuronosyltransferase 1A3.

Green, M. D., King, C. D., Mojarrabi, B., Mackenzie, P. I., & Tephly, T. R. (1998) · PubMed · Cited by 253 · see citing works

Inactivation of androgens by UDP-glucuronosyltransferase enzymes in humans

Bélanger, A., Pelletier, G., Labrie, F., Barbier, O., & Chouinard, S. (2003) · Trends in Endocrinology & Metabolism · doi:10.1016/j.tem.2003.10.005 · Cited by 235 · see citing works

Specificity of human UDP-Glucuronosyltransferases and xenobiotic glucuronidation

Burchell, B., Brierley, C. H., & Rance, D. J. (1995) · Life Sciences · doi:10.1016/0024-3205(95)02073-r · Cited by 224 · see citing works

Isolation and characterization of UGT2B15(Y85): a UDP glucuronosyltransferase encoded by a polymorphic gene

Lévesque, É., Beaulieu, M., Green, M. D., Tephly, T. R., Bélanger, A., & Hum, D. W. (1997) · Pharmacogenetics · doi:10.1097/00008571-199708000-00007 · Cited by 218 · see citing works

A Human Minor Histocompatibility Antigen Resulting from Differential Expression due to a Gene Deletion

Murata, M., Warren, E. H., & Riddell, S. R. (2003) · The Journal of Experimental Medicine · doi:10.1084/jem.20030044 · Cited by 200 · see citing works

3 alpha, 17 beta-androstanediol glucuronide in plasma. A marker of androgen action in idiopathic hirsutism.

Horton, R., HAWKS, D., & Løbo, R. A. (1982) · Journal of Clinical Investigation · doi:10.1172/jci110558 · Cited by 185 · see citing works

Characterization of a common deletion polymorphism of the UGT2B17 gene linked to UGT2B15

Wilson, W., de Villena, F. P., Lyn‐Cook, B. D., Chatterjee, P. K., Bell, T. A., Detwiler, D. A., Gilmore, R. C., Valladeras, I. C., Wright, C. C., Threadgill, D. W., et al. (2004) · Genomics · doi:10.1016/j.ygeno.2004.06.011 · Cited by 155 · see citing works

Role of 17β-Hydroxysteroid Dehydrogenases in Sex Steroid Formation in Peripheral Intracrine Tissues

Labrie, F., Luu-The, V., Lin, S., Simard, J., & Labrie, C. (2000) · Trends in Endocrinology and Metabolism · doi:10.1016/s1043-2760(00)00342-8 · Cited by 143 · see citing works

Peroxisome Proliferator-activated Receptor α Induces Hepatic Expression of the Human Bile Acid Glucuronidating UDP-glucuronosyltransferase 2B4 Enzyme

Barbier, O., Durán-Sandoval, D., Pineda‐Torra, I., Kosykh, V., Fruchart, J., & Staels, B. (2003) · Journal of Biological Chemistry · doi:10.1074/jbc.m305361200 · Cited by 142 · see citing works

Localization of Type 5 17 -Hydroxysteroid Dehydrogenase, 3 -Hydroxysteroid Dehydrogenase, and Androgen Receptor in the Human Prostate by in Situ Hybridization and Immunocytochemistry

Elalfy, M., Luu-The, V., Huang, X., Berger, L., Labrie, F., & Pelletier, G. (1999) · Endocrinology · doi:10.1210/endo.140.3.6585 · Cited by 140 · see citing works

Isolation and Characterization of the UGT2B28 cDNA Encoding a Novel Human Steroid Conjugating UDP-Glucuronosyltransferase

Lévesque, É., Turgeon, D. K., Carrier, J.-S., Montminy, V., Beaulieu, M., & Bélanger, A. (2001) · Biochemistry · doi:10.1021/bi002607y · Cited by 136 · see citing works

Metabolic inactivation of estrogens in breast tissue by UDP-glucuronosyltransferase enzymes: an overview

Guillemette, C., Bélanger, A., & Lépine, J. (2004) · Breast Cancer Research · doi:10.1186/bcr936 · Cited by 123 · see citing works

Cloning and characterization of a novel human olfactory UDP-glucuronosyltransferase

Jedlitschky, G., Cassidy, A., Sales, M., Pratt, N. R., & Burchell, B. (1999) · Biochemical Journal · doi:10.1042/bj3400837 · Cited by 118 · see citing works

Characterization of a cloned human dihydrotestosterone/androstanediol UDP-glucuronosyltransferase and its comparison to other steroid isoforms

Chen, F., Ritter, J. K., Wang, M. G., McBride, O. W., Lubet, R. A., & Owens, I. S. (1993) · Biochemistry · doi:10.1021/bi00091a015 · Cited by 110 · see citing works

Metabolic effects of 12-month percutaneous dehydroepiandrosterone replacement therapy in postmenopausal women

Diamond, P., Cusan, L., Gomez, J.-L., BÉLANGER, A., & Labrie, F. (1996) · Journal of Endocrinology · doi:10.1677/joe.0.150s043 · Cited by 109 · see citing works

Levels of plasma steroid glucuronides in intact and castrated men with prostatic cancer.

BÉLANGER, A., BROCHU, M., & CLICHE, J. (1986) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem-62-5-812 · Cited by 108 · see citing works

Characterization and substrate specificity of UGT2B4 (E458): a UDP-glucuronosyltransferase encoded by a polymorphic gene.

Lévesque, É., Beaulieu, M., Hum, D. W., & Bèlanger, A. (1999) · PubMed · Cited by 108 · see citing works

Deletion Polymorphism of UDP-Glucuronosyltransferase 2B17 and Risk of Prostate Cancer in African American and Caucasian Men

Park, J.-H., Chen, L., Ratnashinge, L., Sellers, T. A., Tanner, J.-P., Lee, J., Dossett, N., Lang, N. P., Kadlubar, F. F., Ambrosone, C. B., et al. (2006) · Cancer Epidemiology Biomarkers & Prevention · doi:10.1158/1055-9965.epi-06-0141 · Cited by 107 · see citing works

KINETIC CHARACTERIZATION OF THE 1A SUBFAMILY OF RECOMBINANT HUMAN UDP-GLUCURONOSYLTRANSFERASES

Luukkanen, L., Taskinen, J., Kurkela, M. J., Kostiainen, R. K., Hirvonen, J. J., & Finel, M. (2005) · Drug Metabolism and Disposition · doi:10.1124/dmd.105.004093 · Cited by 100 · see citing works

Determination of Nonconjugated and Conjugated Steroid Levels in Plasma and Prostate after Separation on C‐18 Columns

Bèlanger, A., Couture, J., Caron, S., & Roy, R. (1990) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.1990.tb34299.x · Cited by 97 · see citing works

Identification and biochemical analysis of novel olfactory-specific cytochrome P-450IIA and UDP-glucuronosyl transferase

Lazard, D., Tal, N., Rubinstein, M., Khen, M., Lancet, D., & Zupko, K. (1990) · Biochemistry · doi:10.1021/bi00484a012 · Cited by 89 · see citing works

An Allele-Specific Polymerase Chain Reaction Method for the Determination of the D85Y Polymorphism in the Human UDPGlucuronosyltransferase 2B15 Gene in a Case-Control Study of Prostate Cancer

MacLeod, S. L., Nowell, S. A., Plaxco, J., & Lang, N. P. (2000) · Annals of Surgical Oncology · doi:10.1007/s10434-000-0777-3 · Cited by 88 · see citing works

Increased UDP-glucuronosyltransferase activity and decreased prostate specific antigen production by biochanin A in prostate cancer cells.

Sun, X., Plouzek, C. A., Henry, J. P., Wang, T. T. Y., & Phang, J. M. (1998) · PubMed · Cited by 88 · see citing works

The Structure and Function of the UDP-Glucuronosyltransferase Gene Family

Burchell, B., Brierley, C. H., Monaghan, G., & Clarke, D. J. (1997) · Advances in pharmacology · doi:10.1016/s1054-3589(08)60758-9 · Cited by 87 · see citing works

Human UDP-Glucuronosyltransferase 2B7

Radominska-Pandya, A., Little, J., & Czernik, P. J. (2001) · Current Drug Metabolism · doi:10.2174/1389200013338379 · Cited by 82 · see citing works

ASP85TYR POLYMORPHISM IN THE UDP-GLUCURONOSYLTRANSFERASE (UGT) 2B15 GENE AND THE RISK OF PROSTATE CANCER

Park, J. M., Chen, L., Shade, K., Lazarus, P. J., Seigne, J. D., Patterson, S. G., Helal, M. A., & Pow‐Sang, J. M. (2004) · The Journal of Urology · doi:10.1097/01.ju.0000117748.44313.43 · Cited by 76 · see citing works

Human Types 1 and 3 3α-Hydroxysteroid Dehydrogenases: Differential Lability and Tissue Distribution1

Dufort, I., Labrie, F., & Luu-The, V. (2001) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.86.2.7216 · Cited by 73 · see citing works

Genotype–phenotype correlation between the polymorphic UGT2B17 gene deletion and NNAL glucuronidation activities in human liver microsomes

Lazarus, P. J., Zheng, Y., Runkle, E. A., Muscat, J. E., & Wiener, D. A. (2005) · Pharmacogenetics and Genomics · doi:10.1097/01.fpc.0000175596.52443.ef · Cited by 71 · see citing works

Estrogen Regulation of the Glucuronidation Enzyme UGT2B15 in Estrogen Receptor-Positive Breast Cancer Cells

Harrington, W. R., Sengupta, S., & Katzenellenbogen, B. S. (2006) · Endocrinology · doi:10.1210/en.2006-0358 · Cited by 64 · see citing works

Androstanediol Glucuronide Plasma Clearance and Production Rates in Normal and Hirsute Women*

Greep, N. C., Hoopes, M. T., & Horton, R. (1986) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem-62-1-22 · Cited by 57 · see citing works

Cellular Specific Expression of the Androgen‐Conjugating Enzymes UGT2B15 and UGT2B17 in the Human Prostate Epithelium

Chouinard, S., Pelletier, G., Bélanger, A., & Barbier, O. (2004) · Endocrine Research · doi:10.1081/erc-200044014 · Cited by 57 · see citing works

Androgen Conjugates: Physiology and Clinical Significance

Rittmaster, R. S. (1993) · Endocrine Reviews · doi:10.1210/edrv-14-1-121 · Cited by 56 · see citing works

Cellular Localization of Uridine Diphosphoglucuronosyltransferase 2B Enzymes in the Human Prostate byin SituHybridization and Immunohistochemistry1

Barbier, O., Lapointe, H., Alfy, M. E., Hum, D. W., & Bélanger, A. (2000) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.85.12.7019 · Cited by 56 · see citing works

Evidence for increased androsterone metabolism in some normoandrogenic women with acne.

Carmina, E., & Løbo, R. A. (1993) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.76.5.8496299 · Cited by 55 · see citing works

Genomic organization of a human 5β-reductase and its pseudogene and substrate selectivity of the expressed enzyme

Charbonneau, A., & The, V. L. (2001) · Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression · doi:10.1016/s0167-4781(00)00278-5 · Cited by 53 · see citing works

Isoform-Specific Regulation of Uridine Diphosphate-Glucuronosyltransferase 2B Enzymes in the Human Prostate: Differential Consequences for Androgen and Bioactive Lipid Inactivation

Chouinard, S., Pelletier, G., Bélanger, A., & Barbier, O. (2006) · Endocrinology · doi:10.1210/en.2006-0229 · Cited by 53 · see citing works

Plasma levels of C-19 steroids and 5α-reduced steroid glucuronides in hyperandrogenic and idiopathic hirsute women

Brochu, M., Bélanger, A., & Tremblay, R. R. (1987) · Fertility and Sterility · doi:10.1016/s0015-0282(16)59589-2 · Cited by 52 · see citing works

Prostate cancer and polymorphism D85Y in gene for dihydrotestosterone degrading enzyme UGT2B15: Frequency of DD homozygotes increases with Gleason Score

Hajdinjak, T., & Zagradišnik, B. (2004) · The Prostate · doi:10.1002/pros.20024 · Cited by 51 · see citing works

Rat olfactory bulb and epithelium UDP-glucuronosyltransferase 2A1 (UGT2A1) expression: in situ mRNA localization and quantitative analysis

Heydel, J., Leclerc, S., Bernard, P., Pelczar, H., Grădinaru, D., Magdalou, J., Minn, A., Artur, Y., & Goudonnet, H. (2001) · Molecular Brain Research · doi:10.1016/s0169-328x(01)00080-8 · Cited by 49 · see citing works

Association of the polymorphisms of genes involved in androgen metabolism and signaling pathways with familial prostate cancer risk in a Japanese population

Okugi, H., Nakazato, H., Matsui, H., Ohtake, N., Nakata, S., & Suzuki, K. (2006) · Cancer Detection and Prevention · doi:10.1016/j.cdp.2006.04.004 · Cited by 47 · see citing works

Levels of plasma C19 steroids and 5 alpha-reduced C19 steroid glucuronides in primates, rodents, and domestic animals

Guillemette, C., Hum, D. W., & Bèlanger, A. (1996) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.1996.271.2.e348 · Cited by 45 · see citing works

The cynomolgus monkey (Macaca fascicularis) is the best animal model for the study of steroid glucuronidation

Barbier, O., & Bélanger, A. (2003) · The Journal of Steroid Biochemistry and Molecular Biology · doi:10.1016/s0960-0760(03)00235-8 · Cited by 39 · see citing works

ANDROSTERONE GLUCURONIDE IS A MARKER OF ADRENAL HYPERANDROGENISM IN HIRSUTE WOMEN

Thompson, D. L., Horton, N., & Rittmaster, R. S. (1990) · Clinical Endocrinology · doi:10.1111/j.1365-2265.1990.tb00868.x · Cited by 37 · see citing works

Cellular Localization of Uridine Diphosphoglucuronosyltransferase 2B Enzymes in the Human Prostate by in Situ Hybridization and Immunohistochemistry

Barbier, O. (2000) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.85.12.4819 · Cited by 36 · see citing works

Human Types 1 and 3 3 -Hydroxysteroid Dehydrogenases: Differential Lability and Tissue Distribution

Dufort, I. (2001) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.86.2.841 · Cited by 35 · see citing works

Regulation of steroid glucuronosyltransferase activities and transcripts by androgen in the human prostatic cancer LNCaP cell line

Guillemette, C., Hum, D. W., & Bèlanger, A. (1996) · Endocrinology · doi:10.1210/endo.137.7.8770908 · Cited by 32 · see citing works

Involvement of Multiple UDP-glucuronosyltransferase 1A Isoforms in Glucuronidation of 5-(4′-hydroxyphenyl)-5-phenylhydantoin in Human Liver Microsomes

Nakajima, M., Sakata, N., Ohashi, N., Kume, T., & Yokoi, T. (2002) · Drug Metabolism and Disposition · doi:10.1124/dmd.30.11.1250 · Cited by 31 · see citing works

Metabolic Effects of 12-Month Percutaneous Dehydroepiandrosterone Replacement Therapy in Postmenopausal Women

Diamond, P., Cusan, L., Gomez, J.-L., Bèlanger, A., & Labrie, F. (1997) · Obstetrical & Gynecological Survey · doi:10.1097/00006254-199707000-00020 · Cited by 29 · see citing works

Origin and significance of plasma androsterone glucuronide levels: a parameter of adrenal androgen secretion and hepatic 5 alpha-reductase activity.

Giagulli, V. A., GIORGINO, R., & Vermeulen, A. (1993) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.76.4.8473406 · Cited by 26 · see citing works

Specificity of glucuronosyltransferase activity in the human cancer cell line LNCaP, evidence for the presence of at least two glucuronosyltransferase enzymes

Guillemette, C., Hum, D. W., & ́langer, A. B. (1995) · The Journal of Steroid Biochemistry and Molecular Biology · doi:10.1016/0960-0760(95)00183-2 · Cited by 23 · see citing works

Unconjugated and Glucuronide Steroid Levels in Human Breast Cyst Fluid

Bèlanger, A., Labrie, F., & Angeli, A. (1990) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.1990.tb17795.x · Cited by 22 · see citing works

Evidence for a role of glucuronosyltransferase in the regulation of androgen action in the human prostatic cancer cell line LNCaP

Guillemette, C., Hum, D. W., & Bélanger, A. (1996) · The Journal of Steroid Biochemistry and Molecular Biology · doi:10.1016/0960-0760(95)00258-8 · Cited by 21 · see citing works

Is plasma 5α-androstane 3α, 17β-diol glucuronide a biochemical marker of hirsutism in women?

Giagulli, V. A., GIORGINO, R., & Vermeulen, A. (1991) · The Journal of Steroid Biochemistry and Molecular Biology · doi:10.1016/0960-0760(91)90013-u · Cited by 19 · see citing works

Increased risk for treatment-related mortality after bone marrow transplantation in GSTM1-positive recipients

Terakura, S., Murata, M., Nishida, T., Emi, N., Akatsuka, Y., MORISHIMA, Y., Kodera, Y., & Naoe, T. (2006) · Bone Marrow Transplantation · doi:10.1038/sj.bmt.1705257 · Cited by 17 · see citing works

Biochemistry of Breast Cyst Fluida

Dogliotti, L., Orlandi, F., Caraci, P., Puligheddu, B., TORTA, M., & Angeli, A. (1990) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.1990.tb17785.x · Cited by 17 · see citing works

Conjugated and unconjugated C-21, C-19 and C-18 steroid concentrations in human follicular fluid from hyperstimulated follicles

Prévost, J., Brochu, M., Bèlanger, A., & Lambert, R. D. (1987) · Gynecological Endocrinology · doi:10.3109/09513598709082705 · Cited by 16 · see citing works

Comparison of plasma androgen glucuronide levels after percutaneous or peroral androgen treatment in men: evidence for important splanchnic contribution to plasma 17 beta-hydroxyandrogen glucuronides

Giagulli, V. A., Verdonck, L., Deslypère, J. P., Giorgino, R., & Vermeulen, A. (1993) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.76.2.429 · Cited by 13 · see citing works

Radioimmunoassay for etiocholanolone

Sato, K., & Ohsawa, N. (1977) · Steroids · doi:10.1016/0039-128x(77)90001-0 · Cited by 5 · see citing works

Sex Differences in the Expression of Hepatic Drug Metabolizing Enzymes

Waxman, D. J., & Holloway, M. G. (2009) · Molecular Pharmacology · doi:10.1124/mol.109.056705 · Cited by 815 · see citing works

The UDP-Glycosyltransferase (UGT) Superfamily: New Members, New Functions, and Novel Paradigms

Meech, R., Hu, D. G., McKinnon, R. A., Mubarokah, S. N., Haines, A. Z., Nair, P. C., Rowland, A., & Mackenzie, P. I. (2019) · Physiological Reviews · doi:10.1152/physrev.00058.2017 · Cited by 363 · see citing works

Steroidogenesis in the skin: Implications for local immune functions

Slominski, A., Zbytek, B., Nikolakis, G., Manna, P. R., Skobowiat, C., Zmijewski, M., Li, W., Janjetovic, Z., Postlethwaite, A., Zouboulis, C. C., et al. (2013) · The Journal of Steroid Biochemistry and Molecular Biology · doi:10.1016/j.jsbmb.2013.02.006 · Cited by 369 · see citing works

Dihydrotestosterone: Biochemistry, Physiology, and Clinical Implications of Elevated Blood Levels

Swerdloff, R. S., Dudley, R. E., Page, S. T., Wang, C., & Salameh, W. A. (2017) · Endocrine Reviews · doi:10.1210/er.2016-1067 · Cited by 247 · see citing works

Sex hormone metabolism in lung development and maturation

Seaborn, T., Simard, M., Provost, P. R., Piedbœuf, B., & Tremblay, Y. (2010) · Trends in Endocrinology and Metabolism · doi:10.1016/j.tem.2010.09.001 · Cited by 152 · see citing works

Functions and transcriptional regulation of adult human hepatic UDP-glucuronosyl-transferases (UGTs): Mechanisms responsible for interindividual variation of UGT levels

Bock, K. W. (2010) · Biochemical Pharmacology · doi:10.1016/j.bcp.2010.04.034 · Cited by 122 · see citing works

3D-Wound healing model: Influence of morphine and solid lipid nanoparticles

Hedtrich, S., Wolf, N. B., Heilmann, S., Weindl, G., Helfmann, J., Yahya, M. M., Stein, C., & Schäfer‐Korting, M. (2010) · Journal of Biotechnology · doi:10.1016/j.jbiotec.2010.01.001 · Cited by 117 · see citing works

Transcriptional regulation of human UDP-glucuronosyltransferase genes

Hu, D. G., Meech, R., McKinnon, R. A., & Mackenzie, P. I. (2014) · Drug Metabolism Reviews · doi:10.3109/03602532.2014.973037 · Cited by 111 · see citing works

Cigarette smoking and testosterone in men and women: A systematic review and meta-analysis of observational studies

Zhao, J., Leung, J. Y. Y., Lin, S. L., & Mary Schooling, C. (2016) · Preventive Medicine · doi:10.1016/j.ypmed.2015.12.021 · Cited by 101 · see citing works

Differences in the Glucuronidation of Resveratrol and Pterostilbene: Altered Enzyme Specificity and Potential Gender Differences

Dellinger, R. W., Garcia, A., & Meyskens, F. L. (2013) · Drug Metabolism and Pharmacokinetics · doi:10.2133/dmpk.dmpk-13-rg-012 · Cited by 82 · see citing works

Genetic polymorphisms of human UDP-glucuronosyltransferase (UGT) genes and cancer risk

Hu, D. G., Mackenzie, P. I., McKinnon, R. A., & Meech, R. (2016) · Drug Metabolism Reviews · doi:10.3109/03602532.2015.1131292 · Cited by 78 · see citing works

Skin steroidogenesis in health and disease

Nikolakis, G., Stratakis, C. A., Kanaki, T., Slominski, A., & Zouboulis, C. C. (2016) · Reviews in Endocrine and Metabolic Disorders · doi:10.1007/s11154-016-9390-z · Cited by 76 · see citing works

The Novel UDP Glycosyltransferase 3A2: Cloning, Catalytic Properties, and Tissue Distribution

Mackenzie, P. I., Rogers, A., Elliot, D. J., Chau, N., Hulin, J.-A., Miners, J. O., & Meech, R. (2010) · Molecular Pharmacology · doi:10.1124/mol.110.069336 · Cited by 76 · see citing works

Serum androgen profile and physical performance in women Olympic athletes

Eklund, E., Berglund, B., Labrie, F., Carlström, K., Ekström, L., & Hirschberg, A. L. (2017) · British Journal of Sports Medicine · doi:10.1136/bjsports-2017-097582 · Cited by 72 · see citing works

A Novel Function for UDP Glycosyltransferase 8: Galactosidation of Bile Acids

Meech, R., Mubarokah, S. N., Shivasami, A., Rogers, A., Nair, P. C., Hu, D. G., McKinnon, R. A., & Mackenzie, P. I. (2014) · Molecular Pharmacology · doi:10.1124/mol.114.093823 · Cited by 66 · see citing works

Multiple roles for UDP-glucuronosyltransferase (UGT)2B15 and UGT2B17 enzymes in androgen metabolism and prostate cancer evolution

Gauthier-Landry, L., Bélanger, A., & Barbier, O. (2015) · The Journal of Steroid Biochemistry and Molecular Biology · doi:10.1016/j.jsbmb.2014.05.009 · Cited by 62 · see citing works

The UGTome: The expanding diversity of UDP glycosyltransferases and its impact on small molecule metabolism

Hu, D. G., Hulin, J.-A., Nair, P. C., Haines, A. Z., McKinnon, R. A., Mackenzie, P. I., & Meech, R. (2019) · Pharmacology & Therapeutics · doi:10.1016/j.pharmthera.2019.107414 · Cited by 55 · see citing works

Roles of human UDP-glucuronosyltransferases in clearance and homeostasis of endogenous substrates, and functional implications

Bock, K. W. (2015) · Biochemical Pharmacology · doi:10.1016/j.bcp.2015.04.020 · Cited by 54 · see citing works

The Ontogeny of UDP-glucuronosyltransferase Enzymes, Recommendations for Future Profiling Studies and Application Through Physiologically Based Pharmacokinetic Modelling

Badée, J., Fowler, S., de Wildt, S. N., Collier, A., Schmidt, S., & Parrott, N. (2018) · Clinical Pharmacokinetics · doi:10.1007/s40262-018-0681-2 · Cited by 43 · see citing works

Androgen Physiology, Pharmacology, and Abuse

Handelsman, D. J. (2015) · Elsevier eBooks · doi:10.1016/b978-0-323-18907-1.00138-4 · Cited by 52 · see citing works

Overexpression of uridine diphospho glucuronosyltransferase 2B17 in high-risk chronic lymphocytic leukemia

Gruber, M., Bellemare, J., Hoermann, G., Gleiß, A., Porpaczy, E. A., Bilban, M., Le, T., Zehetmayer, S., Mannhalter, C., Gaiger, A., et al. (2012) · Blood · doi:10.1182/blood-2012-08-447359 · Cited by 52 · see citing works

Human Cytosolic Hydroxysteroid Dehydrogenases of the Aldo-ketoreductase Superfamily Catalyze Reduction of Conjugated Steroids

Jin, Y., Duan, L., Lee, S. H., Kloosterboer, H. J., Blair, I. A., & Penning, T. M. (2009) · Journal of Biological Chemistry · doi:10.1074/jbc.m809465200 · Cited by 50 · see citing works

Human UDP-glucuronosyltransferases: Feedback loops between substrates and ligands of their transcription factors

Bock, K. W. (2012) · Biochemical Pharmacology · doi:10.1016/j.bcp.2012.07.009 · Cited by 50 · see citing works

Liver Enzymes and Risk of Ischemic Heart Disease and Type 2 Diabetes Mellitus: A Mendelian Randomization Study

Liu, J., Yeung, S. L. A., Lin, S. L., Leung, G. M., & Schooling, C. M. (2016) · Scientific Reports · doi:10.1038/srep38813 · Cited by 51 · see citing works

Androgen Glucuronidation: An Unexpected Target for Androgen Deprivation Therapy, with Prognosis and Diagnostic Implications

Grosse, L., Pâquet, S., Caron, P., Fazli, L., Rennie, P. S., Bélanger, A., & Barbier, O. (2013) · Cancer Research · doi:10.1158/0008-5472.can-13-1462 · Cited by 49 · see citing works

Disposition of Flavonoids via Enteric Recycling: UDP-Glucuronosyltransferase (UGT) 1As Deficiency in Gunn Rats Is Compensated by Increases in UGT2Bs Activities

Wang, S. W. J., Kulkarni, K. H., Tang, L. Y., Wang, J. R., Yin, T., Daidoji, T., Yokota, H., & Hu, M. (2009) · Journal of Pharmacology and Experimental Therapeutics · doi:10.1124/jpet.108.147371 · Cited by 49 · see citing works

Genetic polymorphism in metabolism and host defense enzymes: Implications for human health risk assessment

Ginsberg, G., Guyton, K. Z., Johns, D. O., Schimek, J., Angle, K., & Sonawane, B. R. (2010) · Critical Reviews in Toxicology · doi:10.3109/10408441003742895 · Cited by 47 · see citing works

Regulation of Human UGT2B15 and UGT2B17 by miR-376c in Prostate Cancer Cell Lines

Wijayakumara, D., Hu, D. G., Meech, R., McKinnon, R. A., & Mackenzie, P. I. (2015) · Journal of Pharmacology and Experimental Therapeutics · doi:10.1124/jpet.115.226118 · Cited by 45 · see citing works

Androgen-Stimulated UDP-Glucose Dehydrogenase Expression Limits Prostate Androgen Availability without Impacting Hyaluronan Levels

Wei, Q., Galbenus, R., Raza, A. S., Cerny, R. L., & Simpson, M. A. (2009) · Cancer Research · doi:10.1158/0008-5472.can-08-3083 · Cited by 45 · see citing works

Udp‐glucose dehydrogenase as a novel field‐specific candidate biomarker of prostate cancer

Huang, D., Casale, G. P., Tian, J., Lele, S. M., Писарев, В. М., Simpson, M. A., & Hemstreet, G. P. (2009) · International Journal of Cancer · doi:10.1002/ijc.24820 · Cited by 38 · see citing works

Prostate cancer cells differ in testosterone accumulation, dihydrotestosterone conversion, and androgen receptor signaling response to steroid 5α-reductase inhibitors

Wu, Y., Godoy, A., Azzouni, F. S., Wilton, J. H., Ip, C. C. Y., & Mohler, J. L. (2013) · The Prostate · doi:10.1002/pros.22694 · Cited by 38 · see citing works

Development of a Systematic Approach to Identify Metabolites for Herbal Homologs Based on Liquid Chromatography Hybrid Ion Trap Time-of-Flight Mass Spectrometry: Gender-Related Difference in Metabolism of S chisandra Lignans in Rats

Liang, Y. L., Hao, H., Xie, L. Y., An, K., Xie, T., Zheng, X., Dai, C., Hao, K., Sheng, L., & Wang, G. (2010) · Drug Metabolism and Disposition · doi:10.1124/dmd.110.033373 · Cited by 37 · see citing works

Sexual Dimorphism in Drug Metabolism and Pharmacokinetics

Valodara, A. M., & Johar, K. (2019) · Current Drug Metabolism · doi:10.2174/1389200220666191021094906 · Cited by 35 · see citing works

Contemporary Drug–Drug Interactions in HIV Treatment

Devanathan, A. S., Anderson, D. J. C., Cottrell, M. L., Burgunder, E. M., Saunders, A. C., & Kashuba, A. D. M. (2019) · Clinical Pharmacology & Therapeutics · doi:10.1002/cpt.1393 · Cited by 33 · see citing works

Androgen glucuronides analysis by liquid chromatography tandem-mass spectrometry: could it raise new perspectives in the diagnostic field of hormone-dependent malignancies?

Kalogera, E., Pistos, C., Provatopoulou, X., Athanaselis, S., Spiliopoulou, C., & Gounaris, A. (2013) · Journal of Chromatography B · doi:10.1016/j.jchromb.2013.09.022 · Cited by 31 · see citing works

Simultaneous quantitation of nine hydroxy-androgens and their conjugates in human serum by stable isotope dilution liquid chromatography electrospray ionization tandem mass spectrometry

Zang, T., Tamae, D., Mesaros, C., Wang, Q., Huang, M., Blair, I. A., & Penning, T. M. (2017) · The Journal of Steroid Biochemistry and Molecular Biology · doi:10.1016/j.jsbmb.2016.08.001 · Cited by 29 · see citing works

Association of Uridine Diphosphate-Glucuronosyltransferase 2B Gene Variants with Serum Glucuronide Levels and Prostate Cancer Risk

Grant, D. J., Hoyo, C., Oliver, S., Gerber, L., Shuler, K., Calloway, E. E., Freedland, A. R., McPhail, M. E., Livingston, J. N., Richardson, R. M., et al. (2012) · Genetic Testing and Molecular Biomarkers · doi:10.1089/gtmb.2012.0161 · Cited by 29 · see citing works

Xenobiotic Metabolism in Mice Lacking the UDP-Glucuronosyltransferase 2 Family

Fay, M. J., Nguyen, M. T., Snouwaert, J. N., Dye, R., Grant, D. J., Bodnar, W. M., & Koller, B. H. (2015) · Drug Metabolism and Disposition · doi:10.1124/dmd.115.065482 · Cited by 27 · see citing works

Androgen Physiology, Pharmacology, and Abuse

Handelsman, D. J. (2010) · Elsevier eBooks · doi:10.1016/b978-1-4160-5583-9.00137-4 · Cited by 25 · see citing works

Regulation of endobiotics glucuronidation by ligand-activated transcription factors: physiological function and therapeutic potential

Verreault, M., Kaeding, J., Caron, P., Trottier, J., Grosse, L., Houssin, É., Pâquet, S., Perreault, M., & Barbier, O. (2009) · Drug Metabolism Reviews · doi:10.3109/03602530903219220 · Cited by 24 · see citing works

Forkhead Box Protein A1 Regulates UDP-Glucuronosyltransferase 2B15 Gene Transcription in LNCaP Prostate Cancer Cells

Hu, D. G., & Mackenzie, P. I. (2010) · Drug Metabolism and Disposition · doi:10.1124/dmd.110.035436 · Cited by 24 · see citing works

Anti-Cancer Drugs Elicit Re-Expression of UDP-Glucuronosyltransferases in Melanoma Cells

Dellinger, R. W., Matundan, H. H., Ahmed, A. S., Duong, P. H., & Meyskens, F. L. (2012) · PLoS ONE · doi:10.1371/journal.pone.0047696 · Cited by 24 · see citing works

Novel associations of UDP-glucuronosyltransferase 2B gene variants with prostate cancer risk in a multiethnic study

Vidal, A. C., Tucker, C., Schildkraut, J. M., Richardson, R. M., McPhail, M. E., Freedland, S. J., Hoyo, C., & Grant, D. J. (2013) · BMC Cancer · doi:10.1186/1471-2407-13-556 · Cited by 24 · see citing works

Regulation of human UDP-glycosyltransferase (UGT) genes by miRNAs

Hu, D. G., Mackenzie, P. I., Hulin, J.-A., McKinnon, R. A., & Meech, R. (2022) · Drug Metabolism Reviews · doi:10.1080/03602532.2022.2048846 · Cited by 23 · see citing works

Testosterone accumulation in prostate cancer cells is enhanced by facilitated diffusion

Kaipainen, A., Zhang, A., da Costa, R. M. G., Lucas, J. M., Marck, B. T., Matsumoto, A. M., Morrissey, C. M., True, L. D., Mostaghel, E. A., & Nelson, P. S. (2019) · The Prostate · doi:10.1002/pros.23874 · Cited by 22 · see citing works

Nuclear receptors and endobiotics glucuronidation: the good, the bad, and the UGT

Bigo, C., Caron, S., Dallaire-Théroux, A., & Barbier, O. (2013) · Drug Metabolism Reviews · doi:10.3109/03602532.2012.751992 · Cited by 21 · see citing works

Living alone and psychological well-being in mid-life: does partnership history matter?

Demey, D., Berrington, A. M., Evandrou, M., & Falkingham, J. (2014) · Journal of Epidemiology & Community Health · doi:10.1136/jech-2013-202932 · Cited by 17 · see citing works

Loss of exogenous androgen dependence by prostate tumor cells is associated with elevated glucuronidation potential

Zimmer, B. M., Howell, M. E., Wei, Q., Ma, L., Romsdahl, T., Loughman, E., Markham, J. E., Seravalli, J., Barycki, J. J., & Simpson, M. A. (2016) · Hormones and Cancer · doi:10.1007/s12672-016-0268-z · Cited by 17 · see citing works

UDP-glucuronosyltransferases and biochemical recurrence in prostate cancer progression

Grant, D. J., Chen, Z., Howard, L. E., Wiggins, E. K., Hoedt, A. M. D., Vidal, A. C., Carney, S. T., Squires, J. M., Magyar, C. E., Huang, J., et al. (2017) · BMC Cancer · doi:10.1186/s12885-017-3463-6 · Cited by 17 · see citing works

From differential induction of UDP-glucuronosyltransferases in rat liver to characterization of responsible ligand-activated transcription factors, and their multilevel crosstalk in humans

Bock, K. W. (2011) · Biochemical Pharmacology · doi:10.1016/j.bcp.2011.03.011 · Cited by 17 · see citing works

New insights into the androgen biotransformation in prostate cancer: A regulatory network among androgen, androgen receptors and UGTs

Qin, X., Liu, M., & Wang, X. (2016) · Pharmacological Research · doi:10.1016/j.phrs.2016.02.021 · Cited by 16 · see citing works

Regulation of UDP-Glucuronosyltransferase 2B15 by miR-331-5p in Prostate Cancer Cells Involves Canonical and Noncanonical Target Sites

Wijayakumara, D., Mackenzie, P. I., McKinnon, R. A., Hu, D. G., & Meech, R. (2018) · Journal of Pharmacology and Experimental Therapeutics · doi:10.1124/jpet.117.245936 · Cited by 16 · see citing works

Transcriptome Analysis of Thiram-Treated Zebrafish (Danio rerio) Embryos Reveals Disruption of Reproduction Signaling Pathways

Vasamsetti, B., Chon, K., Choi, J.-Y., Kim, J., & Yoon, C. (2023) · Biology · doi:10.3390/biology12020156 · Cited by 15 · see citing works

Phase Two Steroid Metabolism and Its Roles in Breast and Prostate Cancer Patients

McNamara, K. M., Nakamura, Y., Miki, Y., & Sasano, H. (2013) · Frontiers in Endocrinology · doi:10.3389/fendo.2013.00116 · Cited by 14 · see citing works

Normalized Testosterone Glucuronide as a Potential Urinary Biomarker for Highly Variable UGT2B17 in Children 7–18 Years

Zhang, H., Basit, A., Wolford, C., Chen, K., Gaedigk, A., Lin, Y. S., Leeder, J. S., & Prasad, B. (2020) · Clinical Pharmacology & Therapeutics · doi:10.1002/cpt.1764 · Cited by 13 · see citing works

Potent inhibition of tributyltin (TBT) and triphenyltin (TPT) against multiple UDP-glucuronosyltransferases (UGT): A new potential mechanism underlying endocrine disrupting actions

Lv, H., Wang, J., Wang, M., Shen, L., Xiao, L., Chen, T., Sun, T., Li, W., Zhu, L., & Zhang, X. (2021) · Food and Chemical Toxicology · doi:10.1016/j.fct.2021.112039 · Cited by 13 · see citing works

Genetic variations in UGT2B28, UGT2B17, UGT2B15 genes and the risk of prostate cancer: A case-control study

Habibi, M., Mirfakhraie, R., Khani, M., Rakhshan, A., Azargashb, E., & Pouresmaeili, F. (2017) · Gene · doi:10.1016/j.gene.2017.08.038 · Cited by 12 · see citing works

Androgenic steroid excess in women

Karila, D., Kerlan, V., & Christin‐Maître, S. (2023) · Annales d Endocrinologie · doi:10.1016/j.ando.2023.11.001 · Cited by 11 · see citing works

Morphine Metabolism in Human Skin Microsomes

Heilmann, S., Küchler, S., & Schäfer‐Korting, M. (2012) · Skin Pharmacology and Physiology · doi:10.1159/000342067 · Cited by 11 · see citing works

Genetic Polymorphism of UDP-Glucuronosyltransferase

Mehboob, H., Tahir, I. M., Iqbal, T., Akhter, N., Munir, N., & Riaz, M. (2017) · InTech eBooks · doi:10.5772/intechopen.69206 · Cited by 11 · see citing works

Exemestane and Its Active Metabolite 17-Hydroexemestane Induce UDP-Glucuronosyltransferase (UGT) 2B17 Expression in Breast Cancer Cells

Chanawong, A., Mackenzie, P. I., McKinnon, R. A., Hu, D. G., & Meech, R. (2017) · Journal of Pharmacology and Experimental Therapeutics · doi:10.1124/jpet.117.240317 · Cited by 9 · see citing works

Smoking, sex, risk factors and abdominal aortic aneurysm: is it all down to testosterone?

Schooling, C. M. (2015) · Journal of Epidemiology and Community Health · doi:10.1136/jech-2015-205595 · Cited by 9 · see citing works

The testobolome in microbial testosterone metabolism and human health

Veerus, L., Subrahmanian, A., & Blaser, M. J. (2026) · npj Biofilms and Microbiomes · doi:10.1038/s41522-025-00861-0 · Cited by 8 · see citing works

The Somatic Mutation Landscape of UDP-Glycosyltransferase (UGT) Genes in Human Cancers

Hu, D. G., Marri, S., Hulin, J.-A., McKinnon, R. A., Mackenzie, P. I., & Meech, R. (2022) · Cancers · doi:10.3390/cancers14225708 · Cited by 8 · see citing works

Naftopidil enantiomers suppress androgen accumulation and induce cell apoptosis via the UDP-glucuronosyltransferase 2B15 in benign prostate hyperplasia

Zhan, H., Zhang, S., Li, L., Chen, Z., Cai, Y., Huang, J., Wu, D., Huang, B., Wu, B., & Liu, X. (2022) · The Journal of Steroid Biochemistry and Molecular Biology · doi:10.1016/j.jsbmb.2022.106117 · Cited by 6 · see citing works

Bioanalytical LC–MS Method for the Quantification of Plasma Androgens and Androgen Glucuronides in Breast Cancer

Kalogera, E., Pistos, C. M., Provatopoulou, X., Christophi, C. A., Zografos, G., Stefanidou, M., Spiliopoulou, C., Athanaselis, S., & Gounaris, A. (2016) · Journal of Chromatographic Science · doi:10.1093/chromsci/bmv190 · Cited by 6 · see citing works

Altered glucuronidation deregulates androgen dependent response profiles and signifies castration resistance in prostate cancer

Zimmer, B. M., Howell, M. E., Ma, L., Enders, J. R., Lehman, D. A., Corey, E., Barycki, J. J., & Simpson, M. A. (2021) · Oncotarget · doi:10.18632/oncotarget.28059 · Cited by 6 · see citing works

Promiscuity and Quantitative Contribution of UGT2B17 in Drug and Steroid Metabolism Determined by Experimental and Computational Approaches

Ahire, D. S., Mariasoosai, C., Naji‐Talakar, S., Natesan, S., & Prasad, B. (2024) · Journal of Chemical Information and Modeling · doi:10.1021/acs.jcim.3c01514 · Cited by 6 · see citing works

The evolution of UDP-glycosyl/glucuronosyltransferase 1E (UGT1E) genes in bird lineages is linked to feeding habits but UGT2 genes is not

Kawai, Y. K., Ikenaka, Y., Ishizuka, M., & Kubota, A. (2018) · PLoS ONE · doi:10.1371/journal.pone.0205266 · Cited by 6 · see citing works

Autonomous action and cooperativity between the ONECUT2 transcription factor and its 3′ untranslated region

Steadman, K., You, S., Srinivas, D., Mouakkad, L., Yan, Y., Kim, M., Venugopal, S. V., Tanaka, H., & Freeman, M. R. (2023) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2023.1206259 · Cited by 5 · see citing works

Serum testosterone before and during androgen-deprivation therapy, and prognosis between cigarette smokers and nonsmokers with metastatic prostate cancer

Shiota, M., Kashiwagi, E., Murakami, T., Takeuchi, A., Imada, K., Inokuchi, J., Tatsugami, K., & Eto, M. (2018) · Andrologia · doi:10.1111/and.13119 · Cited by 5 · see citing works

The Variations of Metabolic Detoxification Enzymes Lead to Recurrent Miscarriage and Their Diagnosis Strategy

Song, C., & Shang, W. (2021) · Advances in experimental medicine and biology · doi:10.1007/978-981-33-4187-6_12 · Cited by 4 · see citing works

Phosphorylation of UDP-glucose dehydrogenase increases glycosaminoglycan biosynthesis and promotes tumor cell motility, spheroid growth, and therapeutic resistance

Utz, A. R., Ma, L., Hilovsky, D., Zimmer, B. M., Allego, E., Fluharty, J., Narasimhan, P., Enders, J., Grady, G., Milici, M., et al. (2025) · Matrix Biology · doi:10.1016/j.matbio.2025.10.004 · Cited by 2 · see citing works

Association between serum cotinine and total testosterone in adult males based on NHANES 2011–2016

Liu, M., Gou, Y., Zou, B., Li, X., & Yang, P. (2024) · Scientific Reports · doi:10.1038/s41598-024-74482-6 · Cited by 3 · see citing works

Scaffold attachment factor B1 regulates androgen degradation pathways in prostate cancer.

Yang, J., Chen, Q., You, S., Rotinen, M., Posadas, E. M., Freedland, S. J., Vizio, D. D., Kim, J., & Freeman, M. R. (2021) · Europe PMC (PubMed Central) · Cited by 3 · see citing works

Detection of Total UDP-Glucuronosyltransferase (UGT) Activity in Melanoma Cells

Dellinger, R. W., & Meyskens, F. L. (2015) · Methods in molecular biology · doi:10.1007/7651_2015_298 · Cited by 1 · see citing works

Regulation of uridine diphosphate-glucuronosyltransferase 2B15 expression during ovulation in the rat

Dam, P. T. M., Jang, Y.-J., Park, J.-I., Choi, B. C., Song, S.-J., & Chun, S. (2017) · Endocrine Journal · doi:10.1507/endocrj.ej16-0469 · Cited by 1 · see citing works

Sonic Hedgehog factor Gli1: As good as resistant

Zahreddine, H. A., Čuljković, B., & Borden, K. L. B. (2015) · Molecular & Cellular Oncology · doi:10.4161/23723548.2014.961827 · Cited by 1 · see citing works

Disruptors of Androgen Action and Synthesis

Sanderson, J. T. (2015) · Elsevier eBooks · doi:10.1016/b978-0-12-801139-3.00004-1 · Cited by 1 · see citing works

Lost in Transition - Genetic, Transcriptomic and Breeding Aspects of Metabolic Robustness in Dairy Cows

Ha, N.-T. (2016) · doi:10.53846/goediss-6022

Correction

(2015) · Journal of Epidemiology & Community Health · doi:10.1136/jech-2013-202932corr1 · Cited by 1 · see citing works

Postnatal Hypothalamic-Pituitary-Gonadal Axis Activation (i.e., Minipuberty) in Full-term and Preterm Infants

Kuiri‐Hänninen, T. (2015)

[Advances in medical therapy of hypertension].

Orbegozo, J. M. R. (1953) · PubMed

Current World Literature

(2009) · Current Opinion in Endocrinology Diabetes and Obesity · doi:10.1097/med.0b013e32832c937e

Disruptors of Androgen Action and Synthesis

Sanderson, J. T. (2015) · Elsevier eBooks · doi:10.1016/b978-0-12-821985-0.00021-9

Data from Androgen-Stimulated UDP-Glucose Dehydrogenase Expression Limits Prostate Androgen Availability without Impacting Hyaluronan Levels

Wei, Q., Galbenus, R., Raza, A. S., Cerny, R. L., & Simpson, M. A. (2023) · doi:10.1158/0008-5472.c.6499526.v1

Inclusivity in Epilepsy Care: Navigating the Complex Nature of Seizure Disorders in People Undergoing Gender-Affirming Care

Alick-Lindstrom, S., Weingarten, M. M., Falco-Walter, J. J., Gidal, B. E., Abramowitz, J. D., Lane, C. E., Lerario, M. P., Zeigler, G., & Kerr, W. T. (2025) · Epiliepsy currents/Epilepsy currents · doi:10.1177/15357597251317908

Drug metabolism in cancer patients

Huang, M. (2025) · Elsevier eBooks · doi:10.1016/b978-0-443-29289-7.00024-2

Stable isotope tracing of sex steroids reveals tissue-specific steroid pharmacokinetics and metabolism in intact micePreprint

Giton, F., Vartanian, A. D., Wyckens, N., Ferecatu, I., Chester, M., Héraud, C., Isik, A., Mathis, C., & Guigon, C. J. (2025) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.64898/2025.12.16.694587

UDP-glucuronosyltransferases in sickness and health : Studies on bilirubin and steroid glucuronidation

Sneitz, N. (2013) · Työväentutkimus Vuosikirja

Inactivation of androgens by UDP-glucuronosyltransferases in the human prostate

Barbier, O., & Bélanger, A. (2008) · Best Practice & Research Clinical Endocrinology & Metabolism · doi:10.1016/j.beem.2008.01.001 · Cited by 86 · see citing works

Inactivation of androgens by UDP-glucuronosyltransferase enzymes in humans

Bélanger, A., Pelletier, G., Labrie, F., Barbier, O., & Chouinard, S. (2003) · Trends in Endocrinology & Metabolism · doi:10.1016/j.tem.2003.10.005 · Cited by 235 · see citing works

Multiple roles for UDP-glucuronosyltransferase (UGT)2B15 and UGT2B17 enzymes in androgen metabolism and prostate cancer evolution

Gauthier-Landry, L., Bélanger, A., & Barbier, O. (2015) · The Journal of Steroid Biochemistry and Molecular Biology · doi:10.1016/j.jsbmb.2014.05.009 · Cited by 62 · see citing works

UDP-glucuronosyltransferase 2B15 (UGT2B15) and UGT2B17 enzymes are major determinants of the androgen response in prostate cancer LNCaP cells

Chouinard, S., Barbier, O., & Bélanger, A. (2007) · Journal of Biological Chemistry · doi:10.1074/jbc.m703370200 · Cited by 109 · see citing works

Cellular Specific Expression of the Androgen‐Conjugating Enzymes UGT2B15 and UGT2B17 in the Human Prostate Epithelium

Chouinard, S., Pelletier, G., Bélanger, A., & Barbier, O. (2004) · Endocrine Research · doi:10.1081/erc-200044014 · Cited by 57 · see citing works