Cited by 361Sexual Differentiation and DisordersSteroid Chemistry and BiochemistryAdrenal Hormones and Disorders

The DOI matches its Crossref record; 188 of the 203 references it cites were found in a registry or an index.

The role of 17 beta-hydroxysteroid dehydrogenases

Mindnich, R, Möller, G, Adamski, J·2004·Molecular and Cellular Endocrinology

Abstract

The biological activity of steroid hormones is regulated at the pre-receptor level by several enzymes including 17 beta-hydroxysteroid dehydrogenases (17 beta -HSD). The latter are present in many microorganisms, invertebrates and vertebrates. Dysfunctions in human 17 beta-hydroxysteroid dehydrogenases result in disorders of biology of reproduction and neuronal diseases, the enzymes are also involved in the pathogenesis of various cancers. 17 beta-hydroxysteroid dehydrogenases reveal a remarkable multifunctionality being able to modulate concentrations not only of steroids but as well of fatty and bile acids. Current knowledge on genetics, biochemistry and medical implications is presented in this review.

Overview

Integrity signals

Registry

Crossref · 10.1016/j.mce.2003.12.006

Cites

188 of 188 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Verification

Claims the paper makes

This paper’s full text isn’t openly available, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Citations

Cites

Research works printed but not linked: 5

  1. Brereton, 2001, Pan1b (17betaHSD11): enzymatic activity and distribution in the lung, Mol. Cell Endocrinol., 171/2, 111, 10.1016/S0303-7207(00)00417-2 · DOI
  2. Liu, H., Robert, A., Luu-The, V., 2001. Structure and expression of the gene of a second form of human type 7 17beta-HSD. In: The Endocrine Society 83rd Annual Meeting, Denver, CO, USA, pp. 430.
  3. Mendonca, 1999, 17Beta-hydroxysteroid dehydrogenase 3 deficiency in women, J. Clin. Endocrinol. Metab., 84, 802, 10.1210/jc.84.2.802 · DOI · Paper page
  4. Mindnich, R., Deluca, D., Adamski, J. Identification and characterization of 17beta-hydroxysteroid dehydrogenases in the zebrafish, Danio rerio, Mol. Cell Endocrinol., in press.
  5. Zhang, Y., Dufort, I., Soucy, P., Labrie, F., Luu-The, V., 1995. Cloning and expression of human type V 17β-hydroxysteroid dehydrogenase. In: Proceedings of the 77th Annual Meeting of the Endocrine Society, Washington, DC, pp. 622.

Cited by

Sorted by citations

See all 361

Metadata

Authors
Mindnich, R., Möller, G., & Adamski, J.
Affiliations
Helmholtz Munich (DE)
Corresponding author
Adamski, J
Venue
Molecular and Cellular Endocrinology
Publisher
Elsevier BV
Published
2004-04
Volume
218
Issue
1-2
Pages
7-20
ISSN
0303-7207 (ISSN-L)
OpenAlex
W2083859759
Cited by
354
References
203
Citations by year
2026: 7 · 2025: 11 · 2024: 9 · 2023: 8 · 2022: 13 · 2021: 14 · 2020: 9 · 2019: 11 · 2018: 12 · 2017: 12 · 2016: 13 · 2015: 15 · 2014: 14 · 2013: 8 · 2012: 10
FWCI
2.84
Type
journal article
Language
en
Open access
closed
Locations
  • Molecular and Cellular Endocrinology (publishedVersion)
  • PubMed (publishedVersion)
  • Site cant be reached (submittedVersion)
Funders
Deutsche Forschungsgemeinschaft
Topics
  • Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Sexual Differentiation and Disorders
  • Physical Sciences › Chemistry › Organic Chemistry › Steroid Chemistry and Biochemistry
  • Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Adrenal Hormones and Disorders
Keywords
17β-hydroxysteroid dehydrogenase, steroid hormone metabolism, steroidogenesis, reproductive disorders, neuronal diseases, carcinogenesis, fatty acid metabolism, bile acid metabolism, enzyme genetics, enzyme biochemistry
MeSH terms
Androgens, Animals, Estrogens, Humans, 17-Hydroxysteroid Dehydrogenases, Molecular Structure

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review