Mechanisms of endometrial progesterone resistance

Endometriosis

Giudice, L. C., & Kao, L. C. (2004) · The Lancet · doi:10.1016/s0140-6736(04)17403-5 · Cited by 3,166 · see citing works

Epithelial-mesenchymal transition: at the crossroads of development and tumor metastasis.

Yang, J., & Weinberg, R. (2008) · Developmental Cell · doi:10.1016/j.devcel.2008.05.009 · Cited by 3,135 · see citing works

Sequence and Characterization of a Coactivator for the Steroid Hormone Receptor Superfamily

Oñate, S., Tsai, S., Tsai, M.-J., & O'Malley, B. (1995) · Science · doi:10.1126/science.270.5240.1354 · Cited by 2,507 · see citing works

Endometriosis

Bulun, S. E. (2009) · New England Journal of Medicine · doi:10.1056/nejmra0804690 · Cited by 1,772 · see citing works

Two distinct estrogen-regulated promoters generate transcripts encoding the two functionally different human progesterone receptor forms A and B

Kastner, P., Krust, A., Turcotte, B., Stropp, U., Tora, L., Gronemeyer, H., & Chambon, P. (1990) · The EMBO Journal · doi:10.1002/j.1460-2075.1990.tb08280.x · Cited by 1,534 · see citing works

A Mesenchymal-to-Epithelial Transition Initiates and Is Required for the Nuclear Reprogramming of Mouse Fibroblasts

Li, R., Liang, J., Ni, S., Zhou, T., Qing, X., Li, H., He, W., Chen, J., Li, F., Zhuang, Q., et al. (2010) · Cell stem cell · doi:10.1016/j.stem.2010.04.014 · Cited by 1,129 · see citing works

Molecular Cues to Implantation

Dey, S. K., Lim, H. J., Das, S. K., Reese, J., Paria, B. C., Daikoku, T., & Wang, H. (2004) · Endocrine Reviews · doi:10.1210/er.2003-0020 · Cited by 1,105 · see citing works

Functional genomics reveals a BMP-driven mesenchymal-to-epithelial transition in the initiation of somatic cell reprogramming.

Samavarchi-Tehrani, P., Golipour, A., David, L., Sung, H., Beyer, T. A., Datti, A., Woltjen, K., Nagy, A., & Wrana, J. (2010) · Cell Stem Cell · doi:10.1016/j.stem.2010.04.015 · Cited by 1,035 · see citing works

Physiological Action of Progesterone in Target Tissues

Graham, J. D., & Clarke, C. L. (1997) · Endocrine Reviews · doi:10.1210/edrv.18.4.0308 · Cited by 1,007 · see citing works

Chromatin accessibility pre-determines glucocorticoid receptor binding patterns

John, S., Sabo, P. J., Thurman, R. E., Sung, M.-H., Biddie, S. C., Johnson, T. A., Hager, G. L., & Stamatoyannopoulos, J. A. (2011) · Nature Genetics · doi:10.1038/ng.759 · Cited by 954 · see citing works

Laparoscopic Surgery in Infertile Women with Minimal or Mild Endometriosis

Marcoux, S., Maheux, R., & Bérubé, S. (1997) · New England Journal of Medicine · doi:10.1056/nejm199707243370401 · Cited by 948 · see citing works

The glucocorticoid receptor: rapid exchange with regulatory sites in living cells

McNally, J. G., Müller, W. G., Walker, D., Wolford, R., & Hager, G. L. (2000) · Science · doi:10.1126/science.287.5456.1262 · Cited by 802 · see citing works

Human progesterone receptor A form is a cell- and promoter-specific repressor of human progesterone receptor B function.

Vegeto, E., Shahbaz, M. M., Wen, D. X., Goldman, M. E., O’Malley, B. W., & McDonnell, D. P. (1993) · Molecular Endocrinology · doi:10.1210/mend.7.10.8264658 · Cited by 761 · see citing works

Gene Expression Analysis of Endometrium Reveals Progesterone Resistance and Candidate Susceptibility Genes in Women with Endometriosis

Burney, R. O., Talbi, S., Hamilton, A. E., Vo, K. C., Nyegaard, M., Nezhat, C. R., Lessey, B. A., & Giudice, L. C. (2007) · Endocrinology · doi:10.1210/en.2006-1692 · Cited by 735 · see citing works

Expression Profiling of Endometrium from Women with Endometriosis Reveals Candidate Genes for Disease-Based Implantation Failure and Infertility

Kao, L. C., Germeyer, A., Tulac, S., Lobo, S., Yang, J. P., Taylor, R. N., Osteen, K., Lessey, B. A., & Giudice, L. C. (2003) · Endocrinology · doi:10.1210/en.2003-0043 · Cited by 696 · see citing works

Both corepressor proteins SMRT and N‐CoR exist in large protein complexes containing HDAC3

Li, J., Wang, J., Wang, J., Nawaz, Z., Liu, J. M., Qin, J., & Wong, J. (2000) · The EMBO Journal · doi:10.1093/emboj/19.16.4342 · Cited by 629 · see citing works

Endocrine regulation of menstruation

Jabbour, H. N., Kelly, R. W., Fraser, H. M., & Critchley, H. O. D. (2006) · Endocrine Reviews · doi:10.1210/er.2004-0021 · Cited by 588 · see citing works

Decidualization of the Human Endometrium: Mechanisms, Functions, and Clinical Perspectives

Gellersen, B., Brosens, I., & Brosens, J. J. (2007) · Seminars in Reproductive Medicine · doi:10.1055/s-2007-991042 · Cited by 587 · see citing works

Differential Gene Regulation by the Two Progesterone Receptor Isoforms in Human Breast Cancer Cells

Richer, J. K., Jacobsen, B. M., Manning, N. G., Abel, M. G., Horwitz, K. B., & Wolf, D. M. (2002) · Journal of Biological Chemistry · doi:10.1074/jbc.m110090200 · Cited by 570 · see citing works

Defective mammary gland morphogenesis in mice lacking the progesterone receptor B isoform

Mulac‐Jeričević, B., Lydon, J. P., DeMayo, F. J., & Conneely, O. M. (2003) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1732707100 · Cited by 542 · see citing works

The myometrial junctional zone spiral arteries in normal and abnormal pregnancies

Brosens, J. J., Pijnenborg, R., & Brosens, I. A. (2002) · American Journal of Obstetrics and Gynecology · doi:10.1067/mob.2002.127305 · Cited by 536 · see citing works

Progesterone Receptor Isoform A But Not B Is Expressed in Endometriosis

Attia, G. R. (2000) · Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.85.8.2897 · Cited by 488 · see citing works

Phosphorylation of human progesterone receptors at serine-294 by mitogen-activated protein kinase signals their degradation by the 26S proteasome

Lange, C. A., Shen, T., & Horwitz, K. B. (2000) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.97.3.1032 · Cited by 451 · see citing works

Cyclic AMP and progesterone receptor cross-talk in human endometrium: a decidualizing affair

Gellersen, B., & Brosens, J. J. (2003) · Journal of Endocrinology · doi:10.1677/joe.0.1780357 · Cited by 435 · see citing works

Complete amino acid sequence of the human progesterone receptor deduced from cloned cDNA

Misrahi, M., Atger, M., d’Auriol, L., Loosfelt, H., Mériel, C., Fridlansky, F., Guiochon‐Mantel, A., Galibert, F., & Milgröm, E. (1987) · Biochemical and Biophysical Research Communications · doi:10.1016/0006-291x(87)91416-1 · Cited by 418 · see citing works

Pathogenic mechanisms in endometriosis-associated infertility

Gupta, S., Goldberg, J. M., Aziz, N., Goldberg, E., Krajcir, N., & Agarwal, A. (2008) · Fertility and Sterility · doi:10.1016/j.fertnstert.2008.02.093 · Cited by 409 · see citing works

Natural Selection of Human Embryos: Impaired Decidualization of Endometrium Disables Embryo-Maternal Interactions and Causes Recurrent Pregnancy Loss

Salker, M. S., Teklenburg, G., Molokhia, M., Lavery, S. A., Trew, G. H., Aojanepong, T., Mardon, H. J., Lokugamage, A. U., Rai, R., Landles, C., et al. (2010) · PLoS ONE · doi:10.1371/journal.pone.0010287 · Cited by 403 · see citing works

Progesterone resistance in endometriosis: link to failure to metabolize estradiol.

Bulun, S. E., Cheng, Y.-H., Yin, P., Imir, G., Utsunomiya, H., Attar, E., Innes, J., & Julie Kim, J. (2006) · Molecular and Cellular Endocrinology · doi:10.1016/j.mce.2005.11.041 · Cited by 397 · see citing works

Physiological Action of Progesterone in Target Tissues

Graham, J. D. (1997) · Endocrine Reviews · doi:10.1210/er.18.4.502 · Cited by 386 · see citing works

Reproductive Functions of Progesterone Receptors

Conneely, O. M. (2002) · Recent Progress in Hormone Research · doi:10.1210/rp.57.1.339 · Cited by 379 · see citing works

Adenomyosis in endometriosis—Prevalence and impact on fertility. Evidence from magnetic resonance imaging

Kunz, G., Beil, D., Huppert, P., Noe, M., Kissler, S., & Leyendecker, G. (2005) · Human Reproduction · doi:10.1093/humrep/dei021 · Cited by 377 · see citing works

HOX gene expression is altered in the endometrium of women with endometriosis

Taylor, H. S. (1999) · Human Reproduction · doi:10.1093/humrep/14.5.1328 · Cited by 372 · see citing works

Negative Interaction between the RelA(p65) Subunit of NF-κB and the Progesterone Receptor

Kalkhoven, E., Wissink, S., van der Saag, P. T., & van der Burg, B. (1996) · Journal of Biological Chemistry · doi:10.1074/jbc.271.11.6217 · Cited by 350 · see citing works

Progesterone Regulates Transcription of the p21 Cyclindependent Kinase Inhibitor Gene through Sp1 and CBP/p300

Owen, G. I., Richer, J. K., Tung, L. W., Takimoto, G. S., & Horwitz, K. B. (1998) · Journal of Biological Chemistry · doi:10.1074/jbc.273.17.10696 · Cited by 348 · see citing works

Epigenetics of endometriosis

Guo, S.-W. (2009) · Molecular Human Reproduction · doi:10.1093/molehr/gap064 · Cited by 328 · see citing works

Promoter Hypermethylation of Progesterone Receptor Isoform B (PR-B) in Endometriosis

Wu, Y., Strawn, E., Basir, Z., Halverson, G., & Guo, S. (2006) · Epigenetics · doi:10.4161/epi.1.2.2766 · Cited by 323 · see citing works

The Expanding Cosmos of Nuclear Receptor Coactivators

Lonard, D. M., & O’Malley, B. W. (2006) · Cell · doi:10.1016/j.cell.2006.04.021 · Cited by 317 · see citing works

Progesterone Receptor Regulates Decidual Prolactin Expression in Differentiating Human Endometrial Stromal Cells1

Brosens, J. J., Hayashi, N., & WHITE, J. O. (1999) · Endocrinology · doi:10.1210/endo.140.10.7070 · Cited by 316 · see citing works

Aberrant methylation at HOXA10 may be responsible for its aberrant expression in the endometrium of patients with endometriosis

Wu, Y., Halverson, G., Basir, Z., Strawn, E., Yan, P., & Guo, S.-W. (2005) · American Journal of Obstetrics and Gynecology · doi:10.1016/j.ajog.2005.01.034 · Cited by 283 · see citing works

Adenomyosis in endometriosis – prevalence and impact on fertility. Evidence from magnetic resonance imaging

Bazot, M., Fiori, O., & Daraï, É. (2006) · Human Reproduction · doi:10.1093/humrep/dei448 · Cited by 282 · see citing works

Stromal cells from endometriotic lesions and endometrium from women with endometriosis have reduced decidualization capacity

Klemmt, P. A. B., Carver, J. G., Kennedy, S., Koninckx, P. R., & Mardon, H. J. (2006) · Fertility and Sterility · doi:10.1016/j.fertnstert.2005.08.046 · Cited by 256 · see citing works

The Assembly of Progesterone Receptor-hsp90 Complexes Using Purified Proteins

Kosano, H., Stensgard, B. A., Charlesworth, M. C., McMahon, N., & Toft, D. O. (1998) · Journal of Biological Chemistry · doi:10.1074/jbc.273.49.32973 · Cited by 239 · see citing works

Altered expression of HOXA10 in endometriosis: potential role in decidualization

Kim, J. J., Taylor, H. S., Lu, Z., Ladhani, O., Hastings, J. M., Jackson, K. S., Wu, Y., Guo, S. W., & Fazleabas, A. T. (2007) · MHR: Basic science of reproductive medicine · doi:10.1093/molehr/gam005 · Cited by 228 · see citing works

Transcriptional Cross Talk between the Forkhead Transcription Factor Forkhead Box O1A and the Progesterone Receptor Coordinates Cell Cycle Regulation and Differentiation in Human Endometrial Stromal Cells

Takano, M., Lu, Z., Gotō, T., Fusi, L., HIGHAM, J. M., Francis, J. M., Withey, A., Hardt, J. L., Cloke, B., Stavropoulou, A. V., et al. (2007) · Molecular Endocrinology · doi:10.1210/me.2007-0058 · Cited by 225 · see citing works

Non-genomic progesterone actions in female reproduction

Gellersen, B., Fernandes, M. S., & Brosens, J. J. (2008) · Human Reproduction Update · doi:10.1093/humupd/dmn044 · Cited by 221 · see citing works

Transcriptional characterizations of differences between eutopic and ectopic endometrium

Wu, Y., Kajdacsy-Balla, A., Strawn, E., Basir, Z., Halverson, G., Jailwala, P., Wang, Y., Wang, X., Ghosh, S., & Guo, S.-W. (2006) · Endocrinology · doi:10.1210/en.2005-0426 · Cited by 208 · cited 2× · see citing works

Unfolding the Action of Progesterone Receptors

Li, X., & O’Malley, B. W. (2003) · Journal of Biological Chemistry · doi:10.1074/jbc.r300024200 · Cited by 207 · see citing works

Human progesterone receptor A form is a cell- and promoter-specific repressor of human progesterone receptor B function

Vegeto, E. (1993) · Molecular Endocrinology · doi:10.1210/me.7.10.1244 · Cited by 205 · see citing works

Experimental Murine Endometriosis Induces DNA Methylation and Altered Gene Expression in Eutopic Endometrium1

Lee, B., Du, H., & Taylor, H. S. (2009) · Biology of Reproduction · doi:10.1095/biolreprod.108.070391 · Cited by 204 · see citing works

Cyclic AMP-induced Forkhead Transcription Factor, FKHR, Cooperates with CCAAT/Enhancer-binding Protein β in Differentiating Human Endometrial Stromal Cells

Christian, M., Zhang, X., Schneider‐Merck, T., Unterman, T. G., Gellersen, B., WHITE, J. O., & Brosens, J. J. (2002) · Journal of Biological Chemistry · doi:10.1074/jbc.m201018200 · Cited by 177 · see citing works

A role for menstruation in preconditioning the uterus for successful pregnancy

Brosens, J. J., Parker, M. G., McIndoe, A., Pijnenborg, R., & Brosens, I. A. (2009) · American Journal of Obstetrics and Gynecology · doi:10.1016/j.ajog.2008.11.037 · Cited by 166 · see citing works

Progesterone Resistance in PCOS Endometrium: A Microarray Analysis in Clomiphene Citrate-Treated and Artificial Menstrual Cycles

Savaris, R. F., Groll, J. M., Young, S. L., DeMayo, F. J., Jeong, J.-W., Hamilton, A. E., Giudice, L. C., & Lessey, B. A. (2011) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2010-2600 · Cited by 162 · see citing works

The enigmatic uterine junctional zone: the missing link between reproductive disorders and major obstetrical disorders?

Brosens, I. A., Derwig, I. E., Brosens, J. J., Fusi, L., Benagiano, G., & Pijnenborg, R. (2010) · Human Reproduction · doi:10.1093/humrep/dep474 · Cited by 162 · see citing works

The androgen and progesterone receptors regulate distinct gene networks and cellular functions in decidualizing endometrium

Cloke, B., Huhtinen, K., Fusi, L., Kajihara, T., Yliheikkilä, M., Ho, K.-K., Teklenburg, G., Lavery, S., Jones, M. C., Trew, G., et al. (2008) · Endocrinology · doi:10.1210/en.2008-0356 · Cited by 159 · see citing works

The Inhibitory Function in Human Progesterone Receptor N Termini Binds SUMO-1 Protein to Regulate Autoinhibition and Transrepression

Abdel-Hafiz, H. A., Takimoto, G. S., Tung, L. W., & Horwitz, K. B. (2002) · Journal of Biological Chemistry · doi:10.1074/jbc.m204573200 · Cited by 149 · see citing works

Death or survival – progesterone-dependent cell fate decisions in the human endometrial stroma

Brosens, J. J., & Gellersen, B. (2006) · Journal of Molecular Endocrinology · doi:10.1677/jme.1.02060 · Cited by 146 · see citing works

Invasiveness of human endometrial stromal cells is promoted by decidualization and by trophoblast-derived signals

Gellersen, B., Reimann, K., Samalecos, A., Aupers, S., & Bamberger, A. (2010) · Human Reproduction · doi:10.1093/humrep/dep468 · Cited by 145 · see citing works

Progestins Regulate the Expression and Activity of the Forkhead Transcription Factor FOXO1 in Differentiating Human Endometrium

Labied, S., Kajihara, T., Madureira, P. A., Fusi, L., Jones, M. C., HIGHAM, J. M., Varshochi, R., Francis, J. M., Zoumpoulidou, G., Essafi, A., et al. (2005) · Molecular Endocrinology · doi:10.1210/me.2005-0275 · Cited by 134 · see citing works

Interaction of the τ2 Transcriptional Activation Domain of Glucocorticoid Receptor with a Novel Steroid Receptor Coactivator, Hic-5, Which Localizes to Both Focal Adhesions and the Nuclear Matrix

Yang, L., Guerrero, J., Hong, H., DeFranco, D. B., & Stallcup, M. R. (2000) · Molecular Biology of the Cell · doi:10.1091/mbc.11.6.2007 · Cited by 133 · see citing works

Altered Gene Expression Profiling in Endometrium: Evidence for Progesterone Resistance

Aghajanova, L., Velarde, M. C., & Giudice, L. C. (2010) · Seminars in Reproductive Medicine · doi:10.1055/s-0029-1242994 · Cited by 122 · see citing works

FKBP52 deficiency–conferred uterine progesterone resistance is genetic background and pregnancy stage specific

Tranguch, S., Wang, H., Daikoku, T., Xie, H., Smith, D. F., & Dey, S. K. (2007) · Journal of Clinical Investigation · doi:10.1172/jci31622 · Cited by 121 · see citing works

Regulation of the SUMO pathway sensitizes differentiating human endometrial stromal cells to progesterone

Jones, M. C., Fusi, L., HIGHAM, J. M., Abdel-Hafiz, H. A., Horwitz, K. B., Lam, E. W. ‐., & Brosens, J. J. (2006) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0603002103 · Cited by 115 · see citing works

The expression of interstitial collagenase in human endometrium is controlled by progesterone and by oestradiol and is related to menstruation

Marbaix, É., Kokorine, I., Henriet, P., Donnez, J., Courtoy, P. J., & Eeckhout, Y. (1995) · Biochemical Journal · doi:10.1042/bj3051027 · Cited by 111 · see citing works

RIP140 directs histone and DNA methylation to silence Ucp1 expression in white adipocytes

Kiskinis, E., Hallberg, M., Christian, M., Olofsson, M., Dilworth, S. M., White, R., & Parker, M. G. (2007) · The EMBO Journal · doi:10.1038/sj.emboj.7601908 · Cited by 111 · see citing works

Ligand-Specific Dynamics of the Progesterone Receptor in Living Cells and during Chromatin Remodeling In Vitro

Rayasam, G. V., Elbi, C., Walker, D. A., Wolford, R. G., Fletcher, T. M., Edwards, D. P., & Hager, G. L. (2005) · Molecular and Cellular Biology · doi:10.1128/mcb.25.6.2406-2418.2005 · Cited by 111 · see citing works

Adenomyosis as a disorder of the early and late human reproductive period

Kunz, G., Herbertz, M., Beil, D., Huppert, P., & Leyendecker, G. (2007) · Reproductive BioMedicine Online · doi:10.1016/s1472-6483(10)60535-4 · Cited by 108 · see citing works

Focal cellular origin and regulation of interstitial collagenase (matrix metalloproteinase-1) are related to menstrual breakdown in the human endometrium

Kokorine, I., Marbaix, É., Henriet, P., Okada, Y., Donnez, J., Eeckhout, Y., & Courtoy, P. J. (1996) · Journal of Cell Science · doi:10.1242/jcs.109.8.2151 · Cited by 107 · see citing works

Silencing of the JNK pathway maintains progesterone receptor activity in decidualizing human endometrial stromal cells exposed to oxidative stress signals

Leitao, B., Jones, M. C., Fusi, L., HIGHAM, J. M., Lee, Y. J., Takano, M., Gotō, T., Christian, M., Lam, E. W. ‐., & Brosens, J. J. (2009) · The FASEB Journal · doi:10.1096/fj.09-149153 · Cited by 103 · see citing works

Unique Transcriptome, Pathways, and Networks in the Human Endometrial Fibroblast Response to Progesterone in Endometriosis

Aghajanova, L., Tatsumi, K., Horcajadas, J. A., Zamah, A. M., Esteban, F. J., Herndon, C. N., Conti, M., & Giudice, L. C. (2010) · Biology of Reproduction · doi:10.1095/biolreprod.110.086181 · Cited by 99 · see citing works

Modulation of AP-1 activity by the human progesterone receptor in endometrial adenocarcinoma cells.

Bamberger, A., Bamberger, C. M., Gellersen, B., & Schulte, H. M. (1996) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.93.12.6169 · Cited by 97 · see citing works

Multi-modulation of nuclear receptor coactivators through posttranslational modifications

Han, S. J., Lonard, D. M., & O’Malley, B. W. (2008) · Trends in Endocrinology and Metabolism · doi:10.1016/j.tem.2008.10.001 · Cited by 96 · see citing works

Regulated Expression of Signal Transducer and Activator of Transcription, Stat5, and its Enhancement of PRL Expression in Human Endometrial Stromal Cells in Vitro

Mak, I., Brosens, J. J., Christian, M., Hills, F. A., Chamley, L., Regan, L., & WHITE, J. O. (2002) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.87.6.8576 · Cited by 96 · see citing works

HoxA-11 and FOXO1A Cooperate to Regulate Decidual Prolactin Expression: Towards Inferring the Core Transcriptional Regulators of Decidual Genes

Lynch, V. J., Brayer, K. J., Gellersen, B., & Wagner, G. P. (2009) · PLoS ONE · doi:10.1371/journal.pone.0006845 · Cited by 94 · see citing works

The Protein Kinase A Pathway-Regulated Transcriptome of Endometrial Stromal Fibroblasts Reveals Compromised Differentiation and Persistent Proliferative Potential in Endometriosis

Aghajanova, L., Horcajadas, J. A., Weeks, J. L., Esteban, F. J., NEZHAT, C. R., Conti, M., & Giudice, L. C. (2010) · Endocrinology · doi:10.1210/en.2009-0923 · Cited by 94 · see citing works

Endometriosis and human infertility: a new investigation into the role of eutopic endometrium

Minici, F., Tiberi, F., Tropea, A., Orlando, M., Gangalè, M. F., Romani, F., Campo, S., Bompiani, A., Lanzone, A., & Apa, R. (2007) · Human Reproduction · doi:10.1093/humrep/dem399 · Cited by 89 · see citing works

Functional Association of PR and CCAAT/Enhancer-Binding Proteinβ Isoforms: Promoter-Dependent Cooperation between PR-B and Liver-Enriched Inhibitory Protein, or Liver-Enriched Activatory Protein and PR-A in Human Endometrial Stromal Cells

Christian, M., Pohnke, Y., Kempf, R., Gellersen, B., & Brosens, J. J. (2002) · Molecular Endocrinology · doi:10.1210/mend.16.1.0763 · Cited by 89 · see citing works

Genome-wide mechanisms of nuclear receptor action

Biddie, S. C., John, S., & Hager, G. L. (2010) · Trends in Endocrinology & Metabolism · doi:10.1016/j.tem.2009.08.006 · Cited by 83 · see citing works

The Progesterone Receptor Coactivator Hic-5 Is Involved in the Pathophysiology of Endometriosis

Aghajanova, L., Velarde, M. C., & Giudice, L. C. (2009) · Endocrinology · doi:10.1210/en.2009-0008 · Cited by 82 · see citing works

Steroid receptor action

Brosens, J. J., Tullet, J. M. A., Varshochi, R., & Lam, E. W. ‐. (2004) · Best Practice & Research Clinical Obstetrics & Gynaecology · doi:10.1016/j.bpobgyn.2004.01.006 · Cited by 80 · see citing works

Regulation of Aromatase P450 Expression in Endometriotic and Endometrial Stromal Cells by CCAAT/Enhancer Binding Proteins (C/EBPs): Decreased C/EBPβ in Endometriosis Is Associated with Overexpression of Aromatase

Yang, S., Fang, Z., Suzuki, T., Sasano, H., Zhou, J., Gurates, B., Tamura, M., Ferrer, K., & Bulun, S. (2002) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.87.5.8486 · Cited by 77 · see citing works

Stromal Progesterone Receptors Mediate Induction of Indian Hedgehog (IHH) in Uterine Epithelium and Its Downstream Targets in Uterine Stroma

Simon, L., Spiewak, K. A., Ekman, G. C., et al. (2009) · Endocrinology · doi:10.1210/en.2008-1691 · Cited by 77 · see citing works

Progesterone Receptor Regulates Decidual Prolactin Expression in Differentiating Human Endometrial Stromal Cells

Brosens, J. J. (1999) · Endocrinology · doi:10.1210/en.140.10.4809 · Cited by 76 · see citing works

The Progesterone Receptor Hinge Region Regulates the Kinetics of Transcriptional Responses Through Acetylation, Phosphorylation, and Nuclear Retention

Daniel, A. R., Gaviglio, A. L., Czaplicki, L. M., et al. (2010) · Molecular Endocrinology · doi:10.1210/me.2010-0170 · Cited by 74 · see citing works

Spatiotemporal Coupling of Focal Extracellular Matrix Degradation and Reconstruction in the Menstrual Human Endometrium

Chevronnay, H. P. G., Galant, C., Lemoine, P., Courtoy, P. J., Marbaix, É., & Henriet, P. (2009) · Endocrinology · doi:10.1210/en.2009-0750 · Cited by 73 · see citing works

Progesterone Resistance in a Baboon Model of Endometriosis

Fazleabas, A. T. (2010) · Seminars in Reproductive Medicine · doi:10.1055/s-0029-1242997 · Cited by 69 · see citing works

Role of Steroid Hormone Coregulators in Health and Disease

Thakur, M. K., & Paramanik, V. (2009) · Hormone Research in Paediatrics · doi:10.1159/000201107 · Cited by 68 · see citing works

Systematic expression analysis and antibody screening do not support the existence of naturally occurring progesterone receptor (PR)-C, PR-M, or other truncated PR isoforms.

Samalecos, A., & Gellersen, B. (2008) · Endocrinology · doi:10.1210/en.2008-0602 · Cited by 68 · see citing works

Deficiency of Immunophilin FKBP52 Promotes Endometriosis

Hirota, Y., Tranguch, S., Daikoku, T., Hasegawa, A., Osuga, Y., Taketani, Y., & Dey, S. K. (2008) · The American Journal of Pathology · doi:10.2353/ajpath.2008.080527 · Cited by 67 · see citing works

The SUMO E3-ligase PIAS1 couples reactive oxygen species-dependent JNK activation to oxidative cell death

Leitao, B., Jones, M. C., & Brosens, J. (2011) · The FASEB Journal · doi:10.1096/fj.11-186346 · Cited by 67 · see citing works

Proteomic analysis of endometrium from fertile and infertile patients suggests a role for apolipoprotein A-I in embryo implantation failure and endometriosis

Brosens, J. J., Hodgetts, A., Feroze-Zaidi, F., Sherwin, J. R. A., Fusi, L., Salker, M. S., HIGHAM, J. M., Rose, G. L., Kajihara, T., Young, S. L., et al. (2009) · Molecular Human Reproduction · doi:10.1093/molehr/gap108 · Cited by 66 · see citing works

Association of endometriosis and spontaneous abortion: effect of control group selection

Metzger, D. A., Olive, D. L., Stohs, G. F., & Franklin, R. R. (1986) · Fertility and Sterility · doi:10.1016/s0015-0282(16)49090-4 · Cited by 61 · see citing works

Wild-Type p53 Protein Is Up-Regulated upon Cyclic Adenosine Monophosphate-Induced Differentiation of Human Endometrial Stromal Cells

Pohnke, Y., Schneider‐Merck, T., Fahnenstich, J., Kempf, R., Christian, M., Milde‐Langosch, K., Brosens, J. J., & Gellersen, B. (2004) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2004-0012 · Cited by 57 · see citing works

Dynamic access of the glucocorticoid receptor to response elements in chromatin

George, A. A., Schiltz, R. L., & Hager, G. L. (2008) · The International Journal of Biochemistry & Cell Biology · doi:10.1016/j.biocel.2008.09.019 · Cited by 54 · see citing works

Enhanced invasion of stromal cells from adenomyosis in a three-dimensional coculture model is augmented by the presence of myocytes from affected uteri

Mehasseb, M. K., Taylor, A. H., Pringle, J. H., Bell, S. C., & Habiba, M. A. (2010) · Fertility and Sterility · doi:10.1016/j.fertnstert.2010.04.016 · Cited by 51 · see citing works

Progesterone receptors act as sensors for mitogenic protein kinases in breast cancer models

Dressing, G. E., Hagan, C. R., Knutson, T. P., Daniel, A. R., & Lange, C. A. (2009) · Endocrine Related Cancer · doi:10.1677/erc-08-0281 · Cited by 50 · see citing works

Mechanisms Underlying the Control of Progesterone Receptor Transcriptional Activity by SUMOylation

Abdel-Hafiz, H. A., Dudevoir, M. L., & Horwitz, K. B. (2009) · Journal of Biological Chemistry · doi:10.1074/jbc.m805226200 · Cited by 47 · see citing works

FOXO Transcription Factors: From Cell Fate Decisions to Regulation of Human Female Reproduction

Brosens, J. J., Wilson, M., & Lam, E. W. ‐. (2009) · Advances in experimental medicine and biology · doi:10.1007/978-1-4419-1599-3_17 · Cited by 46 · see citing works

The Endometrial Response to Chorionic Gonadotropin Is Blunted in a Baboon Model of Endometriosis

Sherwin, J. R. A., Hastings, J. M., Jackson, K. S., Mavrogianis, P. A., Sharkey, A., & Fazleabas, A. T. (2010) · Endocrinology · doi:10.1210/en.2010-0275 · Cited by 43 · see citing works

Mechanisms of decidualization

Christian, M., Mak, I., WHITE, J. O., & Brosens, J. J. (2002) · Reproductive BioMedicine Online · doi:10.1016/s1472-6483(12)60112-6 · Cited by 38 · see citing works

FOXO1 and c-jun transcription factors mRNA are modulated in endometriosis

Shazand, K., Baban, S., Privé, C., Malette, B., Croteau, P., Lagacé, M., Racine, J.-B., & Hugo, P. (2004) · Molecular Human Reproduction · doi:10.1093/molehr/gah119 · Cited by 35 · see citing works

Physical Interaction and Mutual Transrepression between CCAAT/Enhancer-binding Protein β and the p53 Tumor Suppressor

Schneider‐Merck, T., Pohnke, Y., Kempf, R., Christian, M., Brosens, J. J., & Gellersen, B. (2005) · Journal of Biological Chemistry · doi:10.1074/jbc.m503459200 · Cited by 34 · see citing works

Immunohistochemical detection of steroid receptor cofactors in ovarian endometriosis: involvement of down-regulated SRC-1 expression in the limited growth activity of the endometriotic epithelium

鈴木, 昭., Horiuchi, A., Oka, K., Miyamoto, T., Kashima, H., & Shiozawa, T. (2010) · Archiv für Pathologische Anatomie und Physiologie und für Klinische Medicin · doi:10.1007/s00428-010-0884-x · Cited by 27 · see citing works

FOXO Transcription Factors and their Role in Disorders of the Female Reproductive Tract

Christian, M., Lam, E. W. ‐., Wilson, M., & Brosens, J. J. (2011) · Current Drug Targets · doi:10.2174/138945011796150253 · Cited by 27 · see citing works

Functional Association of PR and CCAAT/Enhancer-Binding Protein Isoforms: Promoter-Dependent Cooperation between PR-B and Liver-Enriched Inhibitory Protein, or Liver-Enriched Activatory Protein and PR-A in Human Endometrial Stromal Cells

Christian, M. (2002) · Molecular Endocrinology · doi:10.1210/me.16.1.141 · Cited by 27 · see citing works

Preliminary molecular genetic analysis of the Receptor Interacting Protein 140 (RIP140) in women affected by endometriosis

Caballero, V., Ruiz, R., Sainz‐Bueno, J. A., Cruz, M., López‐Nevot, M. Á., Galán, J. J., Real, L. M., de Castro, F., Lopez-Villaverde, V., & Ruiz, A. (2005) · Journal of Experimental & Clinical Assisted Reproduction · doi:10.1186/1743-1050-2-11 · Cited by 26 · see citing works

Menstrual activity of matrix metalloproteinases is decreased in endometrium regenerating after thermal ablation

Brun, J.-L., Galant, C., Delvaux, D., et al. (2008) · Human Reproduction · doi:10.1093/humrep/den392 · Cited by 10 · see citing works

Endometriosis

Zondervan, K. T., Becker, C. M., Koga, K., Missmer, S. A., Taylor, R. N., & Viganò, P. (2018) · Nature Reviews Disease Primers · doi:10.1038/s41572-018-0008-5 · Cited by 1,257 · see citing works

Pathogenesis of endometriosis: The genetic/epigenetic theory

Koninckx, P. R., Ussia, A., Adamyan, L., Wattiez, A., Gomel, V., & Martin, D. C. (2019) · Fertility and Sterility · doi:10.1016/j.fertnstert.2018.10.013 · Cited by 427 · see citing works

Progesterone resistance in endometriosis: origins, consequences and interventions

Patel, B. G., Rudnicki, M., Yu, J., Shu, Y., & Taylor, R. N. (2017) · Acta Obstetricia Et Gynecologica Scandinavica · doi:10.1111/aogs.13156 · Cited by 336 · see citing works

Pathogenesis of deep endometriosis

Gordts, S., Koninckx, P., & Brosens, I. (2017) · Fertility and Sterility · doi:10.1016/j.fertnstert.2017.08.036 · Cited by 241 · see citing works

Human Endometrial Fibroblasts Derived from Mesenchymal Progenitors Inherit Progesterone Resistance and Acquire an Inflammatory Phenotype in the Endometrial Niche in Endometriosis1

Barragan, F., Irwin, J. C., Balayan, S., Erikson, D. W., Chen, J. C., Houshdaran, S., Piltonen, T. T., Spitzer, T. L. B., George, A., Rabban, J. T., et al. (2016) · Biology of Reproduction · doi:10.1095/biolreprod.115.136010 · Cited by 152 · see citing works

Defective myometrial spiral artery remodelling as a cause of major obstetrical syndromes in endometriosis and adenomyosis

Brosens, I., Pijnenborg, R., & Benagiano, G. (2013) · Placenta · doi:10.1016/j.placenta.2012.11.017 · Cited by 135 · see citing works

Risks of adverse pregnancy outcome in endometriosis

Brosens, I., Brosens, J. J., Fusi, L., Al-Sabbagh, M., Kuroda, K., & Benagiano, G. (2012) · Fertility and Sterility · doi:10.1016/j.fertnstert.2012.02.024 · Cited by 132 · see citing works

Cell signaling in trophoblast-uterine communication

Fritz, R., Jain, C., & Armant, D. R. (2014) · The International Journal of Developmental Biology · doi:10.1387/ijdb.140011da · Cited by 86 · see citing works

The impact of uterine immaturity on obstetrical syndromes during adolescence

Brosens, I., Muter, J., Gargett, C. E., Puttemans, P., Benagiano, G., & Brosens, J. J. (2017) · American Journal of Obstetrics and Gynecology · doi:10.1016/j.ajog.2017.05.059 · Cited by 63 · see citing works

The known, the unknown and the future of the pathophysiology of endometriosis

Ochoa Bernal, M. A., & Fazleabas, A. T. (2024) · International Journal of Molecular Sciences · doi:10.3390/ijms25115815 · Cited by 59 · see citing works

Menstrual preconditioning for the prevention of major obstetrical syndromes in polycystic ovary syndrome

Brosens, I., & Benagiano, G. (2015) · American Journal of Obstetrics and Gynecology · doi:10.1016/j.ajog.2015.07.021 · Cited by 31 · see citing works

A Systematic Two-Sample Mendelian Randomization Analysis Identifies Shared Genetic Origin of Endometriosis and Associated Phenotypes

Garitazelaia, A., Rueda-Martínez, A., Arauzo, R., de Miguel, J., Cilleros-Portet, A., Marí, S., Bilbao, J. R., Fernandez-Jimenez, N., & García-Santisteban, I. (2021) · Life · doi:10.3390/life11010024 · Cited by 22 · see citing works

A current view of the role of epigenetic changes in the aetiopathogenesis of endometriosis

Kokcu, A. (2016) · Journal of Obstetrics and Gynaecology · doi:10.3109/01443615.2015.1036403 · Cited by 13 · see citing works

Sex steroids influence organizational but not functional decidualization of feline endometrial cells in a 3D culture system†

Wilsterman, K., Bao, X., Estrada, A. D., Comizzoli, P., & Bentley, G. E. (2019) · Biology of Reproduction · doi:10.1093/biolre/ioz145 · Cited by 6 · see citing works

Expression of tissue inhibitor of metalloproteinases-3 messenger RNA and protein in porcine endometrium during implantation

Ren, Q., Guan, S., Fu, J., et al. (2010) · Molecular Biology Reports · doi:10.1007/s11033-010-0498-z · Cited by 17 · see citing works

Increase of Interstitial Collagen in the Mouse Endometrium During Decidualization

Teodoro, W. R., Witzel, S. S., Velosa, A. P. P., et al. (2003) · Connective Tissue Research · doi:10.1080/713713658 · Cited by 8 · see citing works

Increase of Interstitial Collagen in the Mouse Endometrium During Decidualization

Teodoro, W. R., Witzel, S. S., Velosa, A. P. P., et al. (2003) · Connective Tissue Research · doi:10.1080/03008200390200238 · Cited by 30 · see citing works

DEFECTIVE DECIDUALIZATION AFTER SEVERE PREECLAMPSIA IS CONNECTED TO DYSREGULATION OF PROGESTERONE RECEPTOR B AND ESTROGEN RECEPTOR 1

Garrido‐Gómez, T., Castillo-Marco, N., Muñoz-Blat, I., et al. (2021) · Fertility and Sterility · doi:10.1016/j.fertnstert.2021.07.116