Defective myometrial spiral artery remodelling as a cause of major obstetrical syndromes in endometriosis and adenomyosis
Abstract
Endometriosis and adenomyosis are characterized by the presence of ectopic endometrium, but are also associated with functional and structural changes in the eutopic endometrium and inner myometrium. Alterations in the inner myometrium occurring in women with endometriosis and adenomyosis may be at the root of a defective remodelling of the myometrial spiral arteries from the onset of decidualization and result in vascular resistance and increased risk of defective deep placentation. The association of major obstetrical syndromes and different types of defective remodelling of the myometrial spiral arteries has been well documented. The possibility of a link between both endometriosis and adenomyosis and some major obstetric syndromes remains controversial because of at least two factors: first, changes of the inner myometrium are frequently present in women with endometriosis but the diagnosis requires high-resolution imaging such as magnetic resonance which is not routinely performed and second, patients with endometriosis are frequently subjected to prolonged hormone suppressive therapy. Indeed, there is evidence that pre-treatment with a Gonadotropin Releasing-Hormone analogue can improve the uterine microenvironment and implantation rate following IVF in infertile patients with endometriosis.
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AM-associated disruption of the junctional zone and inner myometrium may lead to placental implantation disorders.
“AM-associated disruption of the junctional zone and the inner myometrium may lead to placental implantation disorders [29,30,31,32].”
From Women with Endometriosis—Who Is at Risk for Complications Associated with Pregnancy and Childbirth? A Retrospective Case–Control Study (2024) · cites this paper as [32]
Cites
Steegers, E. A., von Dadelszen, P., Duvekot, J. J., & Pijnenborg, R. (2010) · The Lancet · doi:10.1016/s0140-6736(10)60279-6 · Cited by 2,850 · see citing works
KHONG, T. Y., DE WOLF, F., ROBERTSON, W. B., & BROSENS, I. (1986) · BJOG: An International Journal of Obstetrics & Gynaecology · doi:10.1111/j.1471-0528.1986.tb07830.x · Cited by 1,591 · see citing works
The “Great Obstetrical Syndromes” are associated with disorders of deep placentation
Brosens, I., Pijnenborg, R., Vercruysse, L., & Romero, R. (2011) · American Journal of Obstetrics and Gynecology · doi:10.1016/j.ajog.2010.08.009 · Cited by 1,568 · see citing works
Ray, J. G., Vermeulen, M. J., Schull, M. J., & Redelmeier, D. A. (2005) · The Lancet · doi:10.1016/s0140-6736(05)67726-4 · Cited by 1,013 · see citing works
The Two Stage Model of Preeclampsia: Variations on the Theme
Roberts, J., & Hubel, C. A. (2008) · Placenta · doi:10.1016/j.placenta.2008.11.009 · Cited by 928 · see citing works
The role of the spiral arteries in the pathogenesis of pre-eclampsia.
Brosens, I. A., Robertson, W. B., & Dixon, H. G. (1970) · PubMed · Cited by 894 · see citing works
The physiological response of the vessels of the placental bed to normal pregnancy
Brosens, I. A., Robertson, W. B., & Dixon, H. G. (1967) · The Journal of Pathology and Bacteriology · doi:10.1002/path.1700930218 · Cited by 792 · see citing works
Pijnenborg, R., Bland, J. M., Robertson, W. B., & Brosens, I. A. (1983) · Placenta · doi:10.1016/s0143-4004(83)80043-5 · Cited by 733 · see citing works
Ion exchange resins in the treatment and prophylaxis of pre-eclampsia.
Brosens, I. A., Wb, R., & Dixon, H. (1953) · PubMed · Cited by 706 · see citing works
The myometrial junctional zone spiral arteries in normal and abnormal pregnancies
Brosens, J. J., Pijnenborg, R., & Brosens, I. A. (2002) · American Journal of Obstetrics and Gynecology · doi:10.1067/mob.2002.127305 · Cited by 536 · see citing works
Uterine artery Doppler at 11 + 0 to 13 + 6 weeks in the prediction of pre‐eclampsia
Plasencia, W., Maiz, N., Bonino, S., Kaihura, C., & Nicolaides, K. H. (2007) · Ultrasound in Obstetrics & Gynecology · doi:10.1002/uog.5157 · Cited by 425 · see citing works
The pathological response of the vessels of the placental bed to hypertensive pregnancy
Robertson, W. B., Brosens, I. A., & Dixon, H. G. (1967) · The Journal of Pathology and Bacteriology · doi:10.1002/path.1700930219 · Cited by 403 · see citing works
Kim, Y. M., Bujold, E., Chaiworapongsa, T., Gómez, R., Yoon, B. H., Thaler, H. T., Rotmensch, S., & Romero, R. J. (2003) · American Journal of Obstetrics and Gynecology · doi:10.1067/s0002-9378(03)00838-x · Cited by 387 · see citing works
Kim, Y. M., Chaiworapongsa, T., Gómez, R., Bujold, E., Yoon, B. H., Rotmensch, S., Thaler, H. T., & Romero, R. J. (2002) · American Journal of Obstetrics and Gynecology · doi:10.1067/mob.2002.127720 · Cited by 280 · see citing works
Extravillous trophoblast and decidual natural killer cells: a remodelling partnership
Wallace, A. E., Fraser, R., & Cartwright, J. E. (2012) · Human Reproduction Update · doi:10.1093/humupd/dms015 · Cited by 245 · see citing works
Endometriosis, assisted reproduction technology, and risk of adverse pregnancy outcome
Stephansson, O., Kieler, H., Granath, F., & Falconer, H. (2009) · Human Reproduction · doi:10.1093/humrep/dep186 · Cited by 234 · see citing works
Mechanisms of endometrial progesterone resistance
Al-Sabbagh, M., Lam, E. W.-F., & Brosens, J. J. (2012) · Molecular and Cellular Endocrinology · doi:10.1016/j.mce.2011.10.035 · Cited by 183 · see citing works
Adenomyosis and risk of preterm delivery
Juang, C., Chou, P., Yen, M., Twu, N., Horng, H., & Hsu, W. (2007) · BJOG: An International Journal of Obstetrics & Gynaecology · doi:10.1111/j.1471-0528.2006.01186.x · Cited by 170 · see citing works
A role for menstruation in preconditioning the uterus for successful pregnancy
Brosens, J. J., Parker, M. G., McIndoe, A., Pijnenborg, R., & Brosens, I. A. (2009) · American Journal of Obstetrics and Gynecology · doi:10.1016/j.ajog.2008.11.037 · Cited by 166 · see citing works
Mehasseb, M. K., Panchal, R., Taylor, A. H., Brown, L., Bell, S. C., & Habiba, M. (2011) · Fertility and Sterility · doi:10.1016/j.fertnstert.2011.02.051 · Cited by 165 · see citing works
Brosens, I. A., Derwig, I. E., Brosens, J. J., Fusi, L., Benagiano, G., & Pijnenborg, R. (2010) · Human Reproduction · doi:10.1093/humrep/dep474 · Cited by 162 · see citing works
Recognition of Trophoblast HLA Class I Molecules by Decidual NK Cell Receptors—A Review
King, A., Hiby, S. E., Gardner, L., Joseph, S., Bowen, J. M., Verma, S., Burrows, T. D., & Loke, Y. W. (2000) · Placenta · doi:10.1053/plac.1999.0520 · Cited by 158 · see citing works
Martínez-Conejero, J. A., Morgan, M., Montesinos, M., Fortuño, S., Meseguer, M., Simón, C., Horcajadas, J. A., & Pellicer, A. (2011) · Fertility and Sterility · doi:10.1016/j.fertnstert.2011.07.1088 · Cited by 151 · see citing works
Preterm birth, ovarian endometriomata, and assisted reproduction technologies
Fernando, S., Breheny, S., Jaques, A. M., Halliday, J. L., Baker, G., & Healy, D. (2009) · Fertility and Sterility · doi:10.1016/j.fertnstert.2008.01.096 · Cited by 150 · see citing works
On an Anatomical Basis for the Increase in Birth Weight in Second and Subsequent Born Children
Khong, T. Y., Adema, E. D., & Erwich, J. J. (2003) · Placenta · doi:10.1053/plac.2002.0922 · Cited by 126 · see citing works
Diffusely Enlarged Uterus: Evaluation with MR Imaging
Kido, A., Togashi, K., Koyama, T., Yamaoka, T., Fujiwara, T., & Fujii, S. (2003) · Radiographics · doi:10.1148/rg.236035033 · Cited by 125 · see citing works
Maubon, A., Faury, A., Kapella, M., Pouquet, M., & Piver, P. (2010) · Journal of obstetrics and gynaecology research · doi:10.1111/j.1447-0756.2010.01189.x · Cited by 121 · see citing works
Adenomyosis and junctional zone changes in patients with endometriosis
Larsen, S. B., Lundorf, E., Forman, A., & Dueholm, M. (2011) · European Journal of Obstetrics & Gynecology and Reproductive Biology · doi:10.1016/j.ejogrb.2011.03.003 · Cited by 110 · see citing works
Adenomyosis as a disorder of the early and late human reproductive period
Kunz, G., Herbertz, M., Beil, D., Huppert, P., & Leyendecker, G. (2007) · Reproductive BioMedicine Online · doi:10.1016/s1472-6483(10)60535-4 · Cited by 108 · see citing works
Mijatovic, V., Florijn, E., Halim, N., Schats, R., & Hompes, P. G. A. (2010) · European Journal of Obstetrics & Gynecology and Reproductive Biology · doi:10.1016/j.ejogrb.2010.02.047 · Cited by 106 · see citing works
Adenomyosis is a potential cause of recurrent implantation failure during IVF treatment
Tremellen, K. P., & Russell, P. (2011) · Australian and New Zealand Journal of Obstetrics and Gynaecology · doi:10.1111/j.1479-828x.2010.01276.x · Cited by 100 · see citing works
Pregnancy outcome in women with endometriomas achieving pregnancy through IVF.
Benaglia, L., Bermejo, A., Somigliana, E., Scarduelli, C., Ragni, G., Fedele, L., & García-Velasco, J. (2011) · Human Reproduction · doi:10.1093/humrep/des054 · Cited by 98 · see citing works
Endometriosis is associated with a decreased risk of pre-eclampsia
Brosens, I. A., Sutter, P. D., Hamerlynck, T. W. O., Imeraj, L., Yao, Z., Cloke, B., Brosens, J. J., & Dhont, M. A. (2007) · Human Reproduction · doi:10.1093/humrep/dem072 · Cited by 97 · see citing works
The Utero-Placental Vessels at Term — the Distribution and Extent of Physiological Changes
Brosens, I. A. (1988) · Springer eBooks · doi:10.1007/978-1-4615-8109-3_5 · Cited by 94 · see citing works
Hadfield, R. M., Lain, S. J., Raynes‐Greenow, C. H., Morris, J. M., & Roberts, C. (2009) · Human Reproduction · doi:10.1093/humrep/dep123 · Cited by 73 · see citing works
In vitro fertilization and embryo transfer outcomes in relation to myometrial thickness
Youm, H. S., Choi, Y. S., & Han, H. D. (2011) · Journal of Assisted Reproduction and Genetics · doi:10.1007/s10815-011-9640-7 · Cited by 68 · see citing works
Santoro, L., D'Onofrio, F., Campo, S., Ferraro, P. M., Tondi, P., Campo, V., Flex, A., Gasbarrini, A., & Santoliquido, A. (2012) · Human Reproduction · doi:10.1093/humrep/des062 · Cited by 66 · see citing works
Obstetric Outcome in Women with Endometriosis – A Matched Case-Control Study
Kortelahti, M., Anttila, M. A., Hippeläinen, M. I., & Heinonen, S. T. (2003) · Gynecologic and Obstetric Investigation · doi:10.1159/000074815 · Cited by 59 · see citing works
Phenotypic Characterisation of the Inner and Outer Myometrium in Normal and Adenomyotic Uteri
Mehasseb, M. K., Bell, S. C., Brown, L. J. R., Pringle, J. H., & Habiba, M. A. (2010) · Gynecologic and Obstetric Investigation · doi:10.1159/000318205 · Cited by 50 · see citing works
Is adenomyosis the neglected phenotype of an endomyometrial dysfunction syndrome?
Brosens, I. A., Kunz, G., & Benagiano, G. (2011) · Gynecological Surgery · doi:10.1007/s10397-011-0723-3 · Cited by 41 · see citing works
Dynamic contrast-enhanced MR imaging to assess physiologic variations of myometrial perfusion
Thomassin‐Naggara, I., Balvay, D., Cuénod, C. A., Daraï, É., Marsault, C., & Bazot, M. (2009) · European Radiology · doi:10.1007/s00330-009-1621-1 · Cited by 39 · see citing works
Patients with adenomyosis are more likely to have deep endometriosis
Gonzales, M., Matos, L. A., Gonçalves, M. O., Blasbalg, R., Dias, J., Podgaec, S., Baracat, E. C., & Abrão, M. S. (2012) · Gynecological Surgery · doi:10.1007/s10397-012-0746-4 · Cited by 25 · see citing works
Xavier, P. A. F., Beires, J., Barros, H., & Martinez‐de‐Oliveira, J. (2005) · Fertility and Sterility · doi:10.1016/j.fertnstert.2005.01.114 · Cited by 23 · see citing works
The uterus under hormonal control – Cycling for life
Brosens, J. J., & Gellersen, B. (2012) · Molecular and Cellular Endocrinology · doi:10.1016/j.mce.2012.02.023 · Cited by 8 · see citing works
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1 of the 46 references couldn’t be matched to a known paper.
Cited by
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Bulun, S. E., Yilmaz, B. D., Sison, C., Miyazaki, K., Bernardi, L., Liu, S., Kohlmeier, A., Yin, P., Milad, M., & Wei, J. (2019) · Endocrine Reviews · doi:10.1210/er.2018-00242 · Cited by 844 · see citing works
Why is placentation abnormal in preeclampsia?
Fisher, S. J. (2015) · American Journal of Obstetrics and Gynecology · doi:10.1016/j.ajog.2015.08.042 · Cited by 632 · see citing works
Uterine adenomyosis and in vitro fertilization outcome: a systematic review and meta-analysis
Vercellini, P., Consonni, D., Dridi, D., Bracco, B., Frattaruolo, M. P., & Somigliana, E. (2014) · Human Reproduction · doi:10.1093/humrep/deu041 · Cited by 411 · see citing works
Vannuccini, S., Clifton, V. L., Fraser, I. S., Taylor, H. S., Critchley, H., Giudice, L. C., & Petraglia, F. (2016) · Human Reproduction Update · doi:10.1093/humupd/dmv044 · Cited by 379 · see citing works
Recent advances in understanding and managing adenomyosis
Vannuccini, S., & Petraglia, F. (2019) · F1000Research · doi:10.12688/f1000research.17242.1 · Cited by 298 · see citing works
Symptoms and classification of uterine adenomyosis, including the place of hysteroscopy in diagnosis
Gordts, S., Grimbizis, G., & Campo, R. (2018) · Fertility and Sterility · doi:10.1016/j.fertnstert.2018.01.006 · Cited by 246 · see citing works
Puente, J. M., Fabris, A. M., Patel, J., Patel, A., Cerrillo, M., Requena, A., & García-Velasco, J. A. (2016) · Reproductive Biology and Endocrinology · doi:10.1186/s12958-016-0185-6 · Cited by 205 · see citing works
Adenomyosis and Abnormal Uterine Bleeding (AUB-A)—Pathogenesis, diagnosis, and management
Abbott, J. A. (2016) · Best Practice & Research Clinical Obstetrics & Gynaecology · doi:10.1016/j.bpobgyn.2016.09.006 · Cited by 209 · see citing works
Barragan, F., Irwin, J. C., Balayan, S., Erikson, D. W., Chen, J. C., Houshdaran, S., Piltonen, T. T., Spitzer, T. L. B., George, A., Rabban, J. T., et al. (2016) · Biology of Reproduction · doi:10.1095/biolreprod.115.136010 · Cited by 152 · see citing works
Pregnancy outcomes in women with endometriosis: a national record linkage study
Saraswat, L., Ayansina, D., Cooper, K. G., Bhattacharya, S., Miligkos, D., Horne, A. W., & Bhattacharya, S. (2016) · BJOG An International Journal of Obstetrics & Gynaecology · doi:10.1111/1471-0528.13920 · Cited by 164 · see citing works
Endometriosis increases the risk of obstetrical and neonatal complications
Berlac, J. F., Hartwell, D., Skovlund, C. W., Langhoff‐Roos, J., & Lidegaard, Ø. (2017) · Acta Obstetricia Et Gynecologica Scandinavica · doi:10.1111/aogs.13111 · Cited by 139 · see citing works
Vigano, P., Corti, L., & Berlanda, N. (2015) · Fertility and Sterility · doi:10.1016/j.fertnstert.2015.08.030 · Cited by 103 · see citing works
Exacoustos, C., Lauriola, I., Lazzeri, L., De Felice, G., & Zupi, E. (2016) · Fertility and Sterility · doi:10.1016/j.fertnstert.2016.06.024 · Cited by 100 · see citing works
Sharma, S., Bathwal, S., Agarwal, N. R., Chattopadhyay, R., Saha, I., & Chakravarty, B. (2018) · Reproductive BioMedicine Online · doi:10.1016/j.rbmo.2018.09.014 · Cited by 99 · see citing works
Oh, S. J., Shin, J., Kim, T. H., Lee, H. S., Yoo, J., Ahn, J. Y., Broaddus, R. R., Taketo, M. M., Lydon, J. P., Leach, R. E., et al. (2013) · The Journal of Pathology · doi:10.1002/path.4224 · Cited by 95 · see citing works
Women with endometriosis at first pregnancy have an increased risk of adverse obstetric outcome
Conti, N., Cevenini, G., Vannuccini, S., Orlandini, C., Valensise, H. C. C., Gervasi, M. T., Ghezzi, F., Tommaso, M. D., Severi, F. M., & Petraglia, F. (2014) · The Journal of Maternal-Fetal & Neonatal Medicine · doi:10.3109/14767058.2014.968843 · Cited by 90 · see citing works
Bruun, M. R., Arendt, L. H., Forman, A., & Ramlau‐Hansen, C. H. (2018) · Acta Obstetricia Et Gynecologica Scandinavica · doi:10.1111/aogs.13364 · Cited by 80 · see citing works
Complications and outcomes of pregnant women with adenomyosis in Japan
Tamura, H., Kishi, H., Kitade, M., Asai‐Sato, M., Tanaka, A., Murakami, T., Minegishi, T., & Sugino, N. (2017) · Reproductive Medicine and Biology · doi:10.1002/rmb2.12050 · Cited by 69 · see citing works
Relationship between adenomyosis and endometriosis; Different phenotypes of a single disease?
Maruyama, S., Imanaka, S., Nagayasu, M., Kimura, M., & Kobayashi, H. (2020) · European Journal of Obstetrics & Gynecology and Reproductive Biology · doi:10.1016/j.ejogrb.2020.08.019 · Cited by 67 · see citing works
Influence of adenomyosis on pregnancy and perinatal outcomes in women with endometriosis
Scala, C., Maggiore, U. L. R., Racca, A., Barra, F., Vellone, V. G., Venturini, P. L., & Ferrero, S. (2017) · Ultrasound in Obstetrics and Gynecology · doi:10.1002/uog.18989 · Cited by 64 · see citing works
Harada, T., Taniguchi, F., Amano, H., Kurozawa, Y., Ideno, Y., Hayashi, K., Harada, T., & Japan Environment and Children’s Study Group (2019) · PLoS ONE · doi:10.1371/journal.pone.0220256 · Cited by 61 · see citing works
A Relationship Between Endometriosis and Obstetric Complications
Kobayashi, H., Kawahara, N., Ogawa, K., & Yoshimoto, C. (2020) · Reproductive Sciences · doi:10.1007/s43032-019-00118-0 · Cited by 57 · see citing works
Le rôle du stress oxydant dans les pathologies placentaires de la grossesse
Jauniaux, E. R. M., & Burton, G. J. (2016) · Journal de gynécologie, obstétrique et biologie de la reproduction. Supplément/Journal de gynécologie obstétrique et biologie de la reproduction · doi:10.1016/j.jgyn.2016.02.012 · Cited by 54 · see citing works
Obstetrical complications of endometriosis, particularly deep endometriosis
Leone Roberti Maggiore, U., Inversetti, A., Schimberni, M., Viganò, P., Giorgione, V., & Candiani, M. (2017) · Fertility and Sterility · doi:10.1016/j.fertnstert.2017.10.035 · Cited by 60 · see citing works
Obstetric Outcomes in Chinese Women with Endometriosis
Lin, H., Leng, J., Liu, J.-T., & Lang, J. (2015) · Chinese Medical Journal · doi:10.4103/0366-6999.151077 · Cited by 53 · see citing works
Vannuccini, S., Lazzeri, L., Orlandini, C., Tosti, C., Clifton, V. L., & Petraglia, F. (2016) · Fertility and Sterility · doi:10.1016/j.fertnstert.2015.12.127 · Cited by 53 · see citing works
Placental malperfusion in response to intrauterine inflammation and its connection to fetal sequelae
Eloundou, S. N., Lee, J. Y., Wu, D., Lei, J., Feller, M. C., Özen, M., Zhu, Y., Hwang, M., Jia, B., Xie, H., et al. (2019) · PLoS ONE · doi:10.1371/journal.pone.0214951 · Cited by 46 · see citing works
Endometriosis and Pregnancy: A Single Institution Experience
Porpora, M. G., Tomao, F., Ticino, A., Piacenti, I., Scaramuzzino, S., Simonetti, S., Imperiale, L., Sangiuliano, C., Masciullo, L., Manganaro, L., et al. (2020) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph17020401 · Cited by 47 · see citing works
Pérez-López, F. R., Villagrasa-Boli, P., Muñoz-Olarte, M., Morera-Grau, Á., Cruz-Andrés, P., Hernandez, A. V., & Health Outcomes and Systematic Analyses (HOUSSAY) Project (2018) · Reproductive Sciences · doi:10.1177/1933719117749760 · Cited by 42 · see citing works
Clinical outcomes of infertility treatment for women with adenomyosis in Japan
Tamura, H., Kishi, H., Kitade, M., Asai‐Sato, M., Tanaka, A., Murakami, T., Minegishi, T., & Sugino, N. (2017) · Reproductive Medicine and Biology · doi:10.1002/rmb2.12036 · Cited by 41 · see citing works
Epelboin, S., Labrosse, J., Fauque, P., Lévy, R., Boyer, M. G., Devaux, A., Bergère, M., de Vienne, C. M., Jonveaux, P., de Mouzon, J., et al. (2020) · Reproductive BioMedicine Online · doi:10.1016/j.rbmo.2020.11.017 · Cited by 37 · see citing works
Adenomyosis and infertility: the role of the junctional zone
Barbanti, C., Centini, G., Lazzeri, L., Habib, N., Labanca, L., Zupi, E., Afors, K., & Starace, A. C. (2021) · Gynecological Endocrinology · doi:10.1080/09513590.2021.1878131 · Cited by 38 · see citing works
Glavind, M. T., Møllgaard, M. V., Iversen, M. L., Arendt, L. H., & Forman, A. (2018) · Best Practice & Research Clinical Obstetrics & Gynaecology · doi:10.1016/j.bpobgyn.2018.01.018 · Cited by 35 · see citing works
Juárez‐Barber, E., Segura-Benítez, M., Carbajo‐García, M. C., Bas-Rivas, A., Faus, A., Vidal, C., Gilés, J., Labarta, E., Pellicer, A., Cervelló, I., et al. (2022) · Reproductive BioMedicine Online · doi:10.1016/j.rbmo.2022.12.008 · Cited by 34 · see citing works
Current facts constituting an understanding of the nature of adenomyosis
Aleksandrovych, V., Basta, P., & Gil, K. (2018) · Advances in Clinical and Experimental Medicine · doi:10.17219/acem/79176 · Cited by 31 · see citing works
Obstetrical complications and outcome in patients with endometriosis
Borisova, A. V., Konnon, S. R., Tosto, V., Gerli, S., & Radzinsky, V. E. (2020) · The Journal of Maternal-Fetal & Neonatal Medicine · doi:10.1080/14767058.2020.1793326 · Cited by 32 · see citing works
Pan, M.-L., Chen, L.-R., Tsao, H.-M., & Chen, K.-H. (2017) · PLoS ONE · doi:10.1371/journal.pone.0181261 · Cited by 30 · see citing works
Salmeri, N., Farina, A., Candiani, M., Dolci, C., Bonavina, G., Poziello, C., Viganò, P., & Cavoretto, P. I. (2022) · Diagnostics · doi:10.3390/diagnostics12051024 · Cited by 30 · see citing works
Palomba, S., Santagni, S., Gibbins, K. J., Sala, G. B. L., & Silver, R. M. (2016) · Reproductive BioMedicine Online · doi:10.1016/j.rbmo.2016.08.007 · Cited by 30 · see citing works
Shinohara, S., Okuda, Y., Hirata, S., & Suzuki, K. (2020) · The Tohoku Journal of Experimental Medicine · doi:10.1620/tjem.251.231 · Cited by 27 · see citing works
Adenomyosis and in vitro fertilization impacts - A literature review
Squillace, A. L. A., Simonian, D. S., Allegro, M. C., Júnior, E. B., Bianchi, P. H. M., & Bibancos, M. (2021) · JBRA · doi:10.5935/1518-0557.20200104 · Cited by 28 · see citing works
Endometriosis and Adverse Pregnancy Outcomes: A Nationwide Population-Based Study
Lim, H. J., Sun, J., Min, B., Song, M., Kim, T. H., Kim, B. J., Hwang, K. R., Lee, T. S., Jeon, H. W., & Kim, S. M. (2023) · Journal of Clinical Medicine · doi:10.3390/jcm12165392 · Cited by 26 · see citing works
Lazzarin, N., Exacoustós, C., Vaquero, E., Felice, G. D., Manfellotto, D., & Zupi, E. (2014) · European Journal of Obstetrics & Gynecology and Reproductive Biology · doi:10.1016/j.ejogrb.2013.12.014 · Cited by 26 · see citing works
The role of the junctional zone in the management of adenomyosis with infertility
Wang, S., & Duan, H. (2023) · Frontiers in Endocrinology · doi:10.3389/fendo.2023.1246819 · Cited by 24 · see citing works
Proangiogenic features in chronic pelvic pain caused by adenomyosis
Orazov, M. R., Носенко, О. М., Radzinsky, V. E., Khamoshina, M. B., Lebedeva, М. G., & Аманович, С. М. (2016) · Gynecological Endocrinology · doi:10.1080/09513590.2016.1232902 · Cited by 24 · see citing works
The importance of the junctional zone of the endometrium in human reproduction
Tanos, V., Lingwood, L., & Balami, S. (2020) · Human Fertility · doi:10.1080/14647273.2020.1720316 · Cited by 24 · see citing works
The association between adenomyosis and recurrent miscarriage
Atabekoğlu, C. S., Şükür, Y. E., Kalafat, E., Özmen, B., Berker, B., Aytaç, R., & Sönmezer, M. (2020) · European Journal of Obstetrics & Gynecology and Reproductive Biology · doi:10.1016/j.ejogrb.2020.05.006 · Cited by 21 · see citing works
Gebremedhin, A. T., Mitter, V. R., Duko, B., Tessema, G. A., & Pereira, G. F. (2023) · Archives of Gynecology and Obstetrics · doi:10.1007/s00404-023-07002-y · Cited by 19 · see citing works
The role of adenomyosis in the pathogenesis of preeclampsia
Hasdemir, P., Farasat, M., Aydin, C., Ozyurt, B., Guvenal, T., & Pekindil, G. (2016) · Geburtshilfe und Frauenheilkunde · doi:10.1055/s-0042-107080 · Cited by 18 · see citing works
Zhou, L., Wang, Y., & Kuang, Y. (2020) · Drug Design Development and Therapy · doi:10.2147/dddt.s263138 · Cited by 18 · see citing works
The Impact of Adenomyosis on Pregnancy and Pregnancy Outcomes: A Review
Wendel, M. P., & Magann, E. F. (2022) · Obstetrical & Gynecological Survey · doi:10.1097/ogx.0000000000001042 · Cited by 18 · see citing works
Kim, Y., Kim, S. H., Kim, J., Sung, J., Choi, S., Oh, S., & Roh, C. (2019) · Taiwanese Journal of Obstetrics and Gynecology · doi:10.1016/j.tjog.2019.07.004 · Cited by 18 · see citing works
Maternal–Fetal Outcomes in Women with Endometriosis and Shared Pathogenic Mechanisms
Frîncu, F., Carp-Velișcu, A., Petca, A., Badiu, D., Brătilă, E., Cîrstoiu, M., & Mehedințu, C. (2021) · Medicina · doi:10.3390/medicina57111258 · Cited by 17 · see citing works
Obstetric Outcome After Surgical Treatment of Endometriosis: A Review of the Literature
Mooney, S. S., Ross, V., Stern, C. J., Rogers, P. A. W., & Healey, M. (2021) · Frontiers in Reproductive Health · doi:10.3389/frph.2021.750750 · Cited by 18 · see citing works
Effects of adenomyosis on obstetric outcomes
Cozzolino, M., Basile, F., & Pontrelli, G. (2019) · Minerva Obstetrics and Gynecology · doi:10.23736/s0026-4784.18.04318-6 · Cited by 17 · see citing works
Adenomyosis: Disease, uterine aging process leading to symptoms, or both?
Πρωτόπαπας, Α., Grimbizis, G., Athanasiou, S., & Loutradis, D. (2020) · PubMed Central · Cited by 17 · see citing works
Endometriosis-Related ceRNA Network to Identify Predictive Biomarkers of Endometrial Receptivity
Wang, X., & Yu, Q. (2019) · Epigenomics · doi:10.2217/epi-2018-0190 · Cited by 16 · see citing works
Endométriose et fausse couche spontanée. Méta-analyse et revue systématique de la littérature
Minebois, H., Souza, A. D., Malartic, C., Agopiantz, M., Guillet‐May, F., Morel, O., & Callec, R. (2017) · Gynécologie Obstétrique Fertilité & Sénologie · doi:10.1016/j.gofs.2017.06.003 · Cited by 16 · see citing works
Adenomyosis and obstetric complications: A retrospective case–control study
de Rozario, T., Jochum, F., Schwaab, T., Garbin, O., Roy, C., & Host, A. (2023) · European Journal of Obstetrics & Gynecology and Reproductive Biology · doi:10.1016/j.ejogrb.2023.11.011 · Cited by 14 · see citing works
Adenomyosis-associated infertility: an update of the immunological perspective
Cao, Y., Yang, D., Cai, S., Yang, L., Yu, S., Geng, Q., Mo, M., Li, W., Wei, Y., Li, Y., et al. (2024) · Reproductive BioMedicine Online · doi:10.1016/j.rbmo.2024.104703 · Cited by 16 · see citing works
Martone, S., Centini, G., Exacoustós, C., Zupi, E., Afors, K., Zullo, F., Maneschi, F., Habib, N., & Lazzeri, L. (2020) · Medical Hypotheses · doi:10.1016/j.mehy.2020.109833 · Cited by 14 · see citing works
Carassou-Maillan, A., Pouly, J.-L., Mulliez, A., Dejou-Bouillet, L., Grémeau, A.-S., Brugnon, F., Janny, L., & Canis, M. J. (2014) · Gynécologie Obstétrique & Fertilité · doi:10.1016/j.gyobfe.2014.01.012 · Cited by 14 · see citing works
Sharifipour, F., Mohaghegh, Z., Javanbakht, Z., Siahkal, S. F., & Azizi, F. (2024) · Reproductive Health · doi:10.1186/s12978-024-01833-x · Cited by 12 · see citing works
Lee, J. Y., Shin, N. E., Na, Q., Dong, J., Chudnovets, A., Su, L., Novak, C. M., McLane, M. W., Lei, J., & Burd, I. D. (2019) · Journal of Reproductive Immunology · doi:10.1016/j.jri.2019.06.004 · Cited by 12 · see citing works
Ono, Y., Ota, H., Takimoto, K., Tsuzuki, Y., Nakajima, A., Yoshino, O., Unno, N., Fujino, T., Fukushi, Y., & Wada, S. (2021) · Journal of Gynecology Obstetrics and Human Reproduction · doi:10.1016/j.jogoh.2021.102114 · Cited by 12 · see citing works
Tanos, V., Balami, S., & Lingwood, L. (2019) · Current Opinion in Obstetrics & Gynecology · doi:10.1097/gco.0000000000000572 · Cited by 12 · see citing works
Deep Infiltrating Endometriosis and Adenomyosis: Implications on Pregnancy and Outcome
Gruber, T. M., Ortlieb, L., Henrich, W., & Mechsner, S. (2021) · Journal of Clinical Medicine · doi:10.3390/jcm11010157 · Cited by 11 · see citing works
Tavarna, T., Phillips, P. L., Wu, X., & Reyes, L. (2020) · Scientific Reports · doi:10.1038/s41598-020-71762-9 · Cited by 11 · see citing works
Millischer, A., Marcellin, L., Santulli, P., Maignien, C., Bourdon, M., Borghese, B., Goffinet, F., & Chapron, C. (2019) · PLoS ONE · doi:10.1371/journal.pone.0223330 · Cited by 11 · see citing works
Naruse, K., Tsunemi, T., Kawahara, N., & Kobayashi, H. (2019) · Placenta · doi:10.1016/j.placenta.2019.02.009 · Cited by 10 · see citing works
Gruber, T. M., Ortlieb, L., Henrich, W., & Mechsner, S. (2024) · Journal of Clinical Medicine · doi:10.3390/jcm13020414 · Cited by 9 · see citing works
“AM-associated disruption of the junctional zone and the inner myometrium may lead to placental implantation disorders [29–32].”
BackgroundZhou, L., Yin, M., Ma, M., Wang, Y., & Kuang, Y. (2019) · Frontiers in Endocrinology · doi:10.3389/fendo.2019.00763 · Cited by 9 · see citing works
Effectiveness of Laparoscopic Adenomyomectomy on Perinatal Outcomes
Ono, Y., Ota, H., Fukushi, Y., Tagaya, H., Okuda, Y., Yoshino, O., Yamada, H., Hirata, S., & Wada, S. (2023) · Gynecology and Minimally Invasive Therapy · doi:10.4103/gmit.gmit_45_22 · Cited by 9 · see citing works
Wang, Y., & Chen, L. (2022) · Journal of Gynecology Obstetrics and Human Reproduction · doi:10.1016/j.jogoh.2022.102349 · Cited by 8 · see citing works
Park, B. Y., Yao, R., Rossi, J., & Lee, A. W. (2023) · Fertility and Sterility · doi:10.1016/j.fertnstert.2023.03.033 · Cited by 8 · see citing works
Interobserver Agreement in the Study of 2D and 3D Sonographic Criteria for Adenomyosis
Puente, J. M., Alcázar, J. L., Martínez-Ten, P., Bermejo, C., Troncoso, M. T., & García-Velasco, J. A. (2017) · Journal of Endometriosis and Pelvic Pain Disorders · doi:10.5301/jeppd.5000295 · Cited by 7 · see citing works
Li, Y., Ge, L., Yang, X., Cui, L., & Chen, Z. (2023) · Frontiers in Medicine · doi:10.3389/fmed.2023.1248274 · Cited by 6 · see citing works
Wang, Y., Hu, Z., Jiang, P., Kong, W., Gong, C., Chen, Y., Xu, L., Yang, Y., & Hu, Z. (2023) · Archives of Gynecology and Obstetrics · doi:10.1007/s00404-023-07136-z · Cited by 5 · see citing works
Kim, M. S., Jang, J. H., Park, S., Ahn, E. H., & Jung, S. H. (2021) · Journal of Obstetrics and Gynaecology · doi:10.1080/01443615.2020.1867969 · Cited by 5 · see citing works
Marcellin, L., Santulli, P., & Chapron, C. (2021) · Elsevier eBooks · doi:10.1016/b978-0-12-820661-4.00013-3 · Cited by 5 · see citing works
Adenomyosis and Obstetrical Outcome: a Narrative Mini-Review of the Latest Evidence
Berlanda, N., Donati, A., Fedele, F., Lepri, M., & Vercellini, P. (2022) · Current Obstetrics and Gynecology Reports · doi:10.1007/s13669-021-00316-1 · Cited by 5 · see citing works
Xu, P., He, X., Zhang, Y., Wang, Y., Zou, G., Wang, J., & Zhang, X. (2024) · Clinical and Experimental Obstetrics & Gynecology · doi:10.31083/j.ceog5101014 · Cited by 4 · see citing works
Transcriptomics and proteomics reveal associations between myometrium and intrauterine adhesions
Xu, X., Guo, K., Zhao, P. Y., Zhang, X., Zhao, P., Sun, X., Zhang, M., Tian, Y., Fen, L., Zheng, J., et al. (2025) · BMC Women s Health · doi:10.1186/s12905-025-03661-y · Cited by 4 · see citing works
Pregnancy outcomes in women with different endometriosis lesion types: A review of current evidence
Munshi, H., Barada, N., Anand, S., & Gajbhiye, R. (2025) · Journal of obstetrics and gynaecology research · doi:10.1111/jog.16321 · Cited by 4 · see citing works
MRI for Diagnosing Intrauterine Adhesions
Kang, K., Wang, A., & Wu, H. (2023) · Journal of Obstetrics and Gynaecology Canada · doi:10.1016/j.jogc.2023.06.004 · Cited by 4 · see citing works
Adénomyose et implantation : mise au point
Yazbeck, C. M., Falcone, S., Ballout, A., Gauché-Cazalis, C., Epelboin, S., Patrat, C., & Luton, D. (2015) · Gynécologie Obstétrique & Fertilité · doi:10.1016/j.gyobfe.2015.09.001 · Cited by 4 · see citing works
Tian, Z., Lai, J., Zhai, Q.-J., Li, Y., Wang, Y., Chang, X., Zhu, H.-L., & Cui, H. (2022) · Gynecology and Obstetrics Clinical Medicine · doi:10.1016/j.gocm.2022.07.001 · Cited by 4 · see citing works
Histopathological Alterations in Fetal Membranes of Women With Endometriosis
Marcellin, L., Méhats, C., & Gogusev, J. (2017) · Reproductive Sciences · doi:10.1177/1933719117728804 · Cited by 4 · see citing works
Sharma, S., RoyChoudhury, S., Karan, M., Shaw, K., Paladhi, P., Palchaudhuri, P., Datta, D., Chattopadhyay, R., & Majhi, A. K. (2025) · Gynecologic and Obstetric Investigation · doi:10.1159/000546437 · Cited by 3 · see citing works
Etrusco, A., Agrifoglio, V., D’Amato, A., Nigris, A. D., Maggiore, U. L. R., Donna, M. C. D., Riemma, G., & Cozzolino, M. (2025) · American Journal of Obstetrics and Gynecology · doi:10.1016/j.ajog.2025.11.008 · Cited by 5 · see citing works
Shen, M.-J., Pan, D., Du, L., & Jiang, G.-J. (2022) · EXPLORE · doi:10.1016/j.explore.2022.03.009 · Cited by 3 · see citing works
Küpker, W., Aizpurúa, J., Felberbaum, R. E., & Diedrich, K. (2024) · Die Gynäkologie · doi:10.1007/s00129-024-05203-3 · Cited by 3 · see citing works
Ota, Y., Ota, K., Takahashi, T., Horikawa, N., Kuroda, R., Okamoto, H., Tanaka, Y., 楠本, 知., Oda, T., Matsuyama, T., et al. (2024) · Frontiers in Medicine · doi:10.3389/fmed.2024.1457611 · Cited by 3 · see citing works
Ying, X., & Yu, H. (2025) · International Journal of Gynecology & Obstetrics · doi:10.1002/ijgo.70272 · Cited by 3 · see citing works
Annicchino, G., Malvezzi, H., Piccinato, C. D. A., & Podgaec, S. (2020) · Revista Brasileira Ginecologia e Obstetrícia · doi:10.1055/s-0040-1708885 · Cited by 3 · see citing works
Gebremedhin, A. T., Mitter, V. R., Duko, B., Tessema, G. A., & Pereira, G. F. (2023) · Research Square · doi:10.21203/rs.3.rs-2462392/v1 · Cited by 3 · see citing works
Clinical features and perinatal outcomes in women with adenomyosis
Lü, L., Zhang, K., Gao, X., Wang, M., & Guo, H. (2025) · European Journal of Obstetrics & Gynecology and Reproductive Biology · doi:10.1016/j.ejogrb.2025.114631 · Cited by 2 · see citing works
Adenomyosis and IVF Outcomes - where we are and where we need to be
Maheshwari, A., & Bhattacharya, S. (2017) · Journal of Endometriosis and Pelvic Pain Disorders · doi:10.5301/jeppd.5000291 · Cited by 2 · see citing works
Lisovskaya, T. V., Malgina, G. B., Perepletina, T. A., Chistyakov, M. A., Dankova, I. V., & Melkozerova, O. A. (2016) · Gynecological Endocrinology · doi:10.1080/09513590.2016.1232246 · Cited by 2 · see citing works
Pregnancy outcomes in patients with uterine junctional zone thickening
Константиновна, О. Е., Zhandarova, O. A., & Kogan, I. Y. (2020) · Journal of obstetrics and women s diseases · doi:10.17816/jowd69569-75 · Cited by 2 · see citing works
- Authors
- Brosens, I., Pijnenborg, R., & Benagiano, G.
- Affiliations
- Leuven Institute for Fertility and Embryology (BE)
- Universitair Ziekenhuis Leuven (BE)
- Sapienza University of Rome (IT)
- Corresponding author
- Brosens, I.
- Venue
- Placenta
- Publisher
- Elsevier BV
- Published
- 2013-02
- Volume
- 34
- Issue
- 2
- Pages
- 100-105
- ISSN
- 0143-4004 (ISSN-L)
- OpenAlex
- W2039845234
- Cited by
- 135
- References
- 46
- Citations by year
- 2026: 9 · 2025: 9 · 2024: 11 · 2023: 13 · 2022: 10 · 2021: 10 · 2020: 15 · 2019: 14 · 2018: 8 · 2017: 10 · 2016: 12 · 2015: 7 · 2014: 6 · 2013: 1
- FWCI
- 0.61
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Placenta (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Reproductive Medicine › Endometriosis Research and Treatment
- Health Sciences › Medicine › Obstetrics and Gynecology › Pregnancy and preeclampsia studies
- Life Sciences › Immunology and Microbiology › Immunology › Reproductive System and Pregnancy
- Keywords
- endometriosis, adenomyosis, spiral artery remodeling, decidualization, vascular resistance, GnRH analogues, uterine microenvironment, implantation rate, in vitro fertilization
- MeSH terms
- Abortion, Spontaneous, Endometriosis, Female, Humans, Infant, Newborn, Myometrium, Pituitary Gland, Pre-Eclampsia, Pregnancy, Pregnancy Complications, Pregnancy Outcome, Risk Factors, Syndrome, Vascular Resistance, Reproductive Techniques, Assisted, Premature Birth, Uterine Artery, Adenomyosis
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