Resveratrol attenuates high-fat diet–induced insulin resistance by influencing skeletal muscle lipid transport and subsarcolemmal mitochondrial β-oxidation

Increased oxidative stress in obesity and its impact on metabolic syndrome

Furukawa, S., Fujita, T., Shimabukuro, M., Iwaki, M., Yamada, Y., Nakajima, Y., Nakayama, O., Makishima, M., Matsuda, M., & Shimomura, I. (2004) · Journal of Clinical Investigation · doi:10.1172/jci21625 · Cited by 5,508 · see citing works

Resveratrol improves health and survival of mice on a high-calorie diet

Baur, J. A., Pearson, K. J., Price, N. L., Jamieson, H. A., Lerin, C., Kalra, A., Prabhu, V. V., Allard, J. S., Lopez-Lluch, G., Lewis, K., et al. (2006) · Nature · doi:10.1038/nature05354 · Cited by 4,290 · see citing works

Resveratrol Improves Mitochondrial Function and Protects against Metabolic Disease by Activating SIRT1 and PGC-1α

Lagouge, M., Argmann, C., Gerhart-Hines, Z., Meziane, H., Lerin, C., Daussin, F., Messadeq, N., Milne, J., Lambert, P., Elliott, P., et al. (2006) · Cell · doi:10.1016/j.cell.2006.11.013 · Cited by 4,057 · see citing works

Impaired Mitochondrial Activity in the Insulin-Resistant Offspring of Patients with Type 2 Diabetes

Petersen, K. F., Dufour, S., Befroy, D., Garcia, R., & Shulman, G. I. (2004) · New England Journal of Medicine · doi:10.1056/nejmoa031314 · Cited by 2,193 · see citing works

Small molecule activators of SIRT1 as therapeutics for the treatment of type 2 diabetes

Milne, J. C., Lambert, P. D., Schenk, S., Carney, D. P., Smith, J. J., Gagne, D. J., Jin, L., Boss, O., Perni, R. B., Vu, C. B., et al. (2007) · Nature · doi:10.1038/nature06261 · Cited by 1,707 · see citing works

AMPK: An Emerging Drug Target for Diabetes and the Metabolic Syndrome

Zhang, B. B., Zhou, G., & Li, C. (2009) · Cell Metabolism · doi:10.1016/j.cmet.2009.03.012 · Cited by 1,028 · see citing works

Molecular mechanisms of insulin resistance in humans and their potential links with mitochondrial dysfunction

Morino, K., Petersen, K. F., & Shulman, G. I. (2006) · Diabetes · doi:10.2337/db06-s002 · Cited by 853 · see citing works

SIRT1 Improves Insulin Sensitivity under Insulin-Resistant Conditions by Repressing PTP1B

Sun, C., Zhang, F., Ge, X., Yan, T., Chen, X., Shi, X., & Zhai, Q. (2007) · Cell Metabolism · doi:10.1016/j.cmet.2007.08.014 · Cited by 766 · see citing works

Membrane Fatty Acid Transporters as Regulators of Lipid Metabolism: Implications for Metabolic Disease

Glatz, J. F. C., Luiken, J. J. F. P., & Bonen, A. (2010) · Physiological Reviews · doi:10.1152/physrev.00003.2009 · Cited by 757 · see citing works

Specific SIRT1 Activation Mimics Low Energy Levels and Protects against Diet-Induced Metabolic Disorders by Enhancing Fat Oxidation

Feige, J. N., Lagouge, M., Canto, C., Strehle, A., Houten, S. M., Milne, J. C., Lambert, P. D., Mataki, C., Elliott, P. J., & Auwerx, J. (2008) · Cell Metabolism · doi:10.1016/j.cmet.2008.08.017 · Cited by 719 · see citing works

SirT1 Gain of Function Increases Energy Efficiency and Prevents Diabetes in Mice

Banks, A. S., Kon, N., Knight, C. M., Matsumoto, M., Juárez, R. G., Rossetti, L., Gu, W. J., & Accili, D. (2008) · Cell Metabolism · doi:10.1016/j.cmet.2008.08.014 · Cited by 636 · see citing works

Insulin signaling coordinately regulates cardiac size, metabolism, and contractile protein isoform expression

Belke, D. D., Bétuing, S., Tuttle, M. J., Graveleau, C., Young, M. E., Pham, M., Zhang, D., Cooksey, R. C., McClain, D. A., Litwin, S. E., et al. (2002) · Journal of Clinical Investigation · doi:10.1172/jci13946 · Cited by 377 · see citing works

Overexpression of carnitine palmitoyltransferase-1 in skeletal muscle is sufficient to enhance fatty acid oxidation and improve high-fat diet–induced insulin resistance

Bruce, C. R., Hoy, A. J., Turner, N., Watt, M. J., Allen, T. L., Carpenter, K., Cooney, G. J., Febbraio, M. A., & Kraegen, E. W. (2009) · Diabetes · doi:10.2337/db08-1078 · Cited by 363 · see citing works

Insulin signaling coordinately regulates cardiac size, metabolism, and contractile protein isoform expression

Belke, D. D., Betuing, S., Tuttle, M. J., Graveleau, C., Young, M. E., Pham, M., Zhang, D., Cooksey, R. C., McClain, D. A., Litwin, S. E., et al. (2002) · Journal of Clinical Investigation · doi:10.1172/jci0213946 · Cited by 330 · see citing works

Resveratrol-Associated Renal Toxicity

Crowell, J. A. (2004) · Toxicological Sciences · doi:10.1093/toxsci/kfh263 · Cited by 321 · see citing works

Paradoxical effects of increased expression of PGC-1α on muscle mitochondrial function and insulin-stimulated muscle glucose metabolism

Choi, C. S., Befroy, D. E., Codella, R., Kim, S., Reznick, R. M., Hwang, Y.-J., Liu, Z.-X., Lee, H.-Y., Distefano, A., Samuel, V. T., et al. (2008) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0810339105 · Cited by 279 · see citing works

Defective fatty acid uptake modulates insulin responsiveness and metabolic responses to diet in CD36-null mice

Hajri, T., Han, X. X., Bonen, A., & Abumrad, N. A. (2002) · Journal of Clinical Investigation · doi:10.1172/jci14596 · Cited by 277 · see citing works

Intramyocellular lipid content in type 2 diabetes patients compared with overweight sedentary men and highly trained endurance athletes

van Loon, L. J. C., Koopman, R., Manders, R., van der Weegen, W., van Kranenburg, G. P., & Keizer, H. A. (2004) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.00464.2003 · Cited by 239 · see citing works

Defective fatty acid uptake modulates insulin responsiveness and metabolic responses to diet in CD36-null mice

Hajri, T., Han, X. X., Bonen, A., & Abumrad, N. A. (2002) · Journal of Clinical Investigation · doi:10.1172/jci0214596 · Cited by 228 · see citing works

Modest PGC-1α Overexpression in Muscle in Vivo Is Sufficient to Increase Insulin Sensitivity and Palmitate Oxidation in Subsarcolemmal, Not Intermyofibrillar, Mitochondria

Benton, C. R., Nickerson, J. G., Lally, J., Han, X.-X., Holloway, G. P., Glatz, J. F. C., Luiken, J. J. F. P., Graham, T. E., Heikkila, J. J., & Bonen, A. (2008) · Journal of Biological Chemistry · doi:10.1074/jbc.m704332200 · Cited by 214 · see citing works

Skeletal muscle mitochondria in insulin resistance: differences in intermyofibrillar versus subsarcolemmal subpopulations and relationship to metabolic flexibility

Chomentowski, P., Coen, P. M., Radiková, Z., Goodpaster, B. H., & Toledo, F. G. S. (2011) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2010-0822 · Cited by 163 · see citing works

Increased subsarcolemmal lipids in type 2 diabetes: effect of training on localization of lipids, mitochondria, and glycogen in sedentary human skeletal muscle

Nielsen, J., Mogensen, M., Vind, B. F., Sahlin, K., Højlund, K., Schrøder, H. D., & Ørtenblad, N. (2009) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.00692.2009 · Cited by 158 · see citing works

Assessing mitochondria biogenesis

Medeiros, D. M. (2008) · Methods · doi:10.1016/j.ymeth.2008.09.026 · Cited by 135 · see citing works

Muscle-Specific Adaptations, Impaired Oxidative Capacity and Maintenance of Contractile Function Characterize Diet-Induced Obese Mouse Skeletal Muscle

Shortreed, K. E., Krause, M. P., Huang, J. H., Dhanani, D., Moradi, J., Ceddia, R. B., & Hawke, T. J. (2009) · PLoS ONE · doi:10.1371/journal.pone.0007293 · Cited by 131 · see citing works

SIRT1 mRNA expression may be associated with energy expenditure and insulin sensitivity

Rutanen, J., Yaluri, N., Modi, S., Pihlajamäki, J., Vänttinen, M., Itkonen, P., Kainulainen, S., Yamamoto, H., Lagouge, M., Sinclair, D. A., et al. (2010) · Diabetes · doi:10.2337/db09-1191 · Cited by 104 · see citing works

Structural and functional characterization of the mouse fatty acid translocase promoter: activation during adipose differentiation

Teboul, L., Febbraio, M., Gaillard, D., Amri, E., Silverstein, R. L., & Grimaldi, P. A. (2001) · Biochemical Journal · doi:10.1042/0264-6021:3600305 · Cited by 76 · see citing works

Altered Skeletal Muscle Subsarcolemmal Mitochondrial Compartment During Catch-Up Fat After Caloric Restriction

Crescenzo, R., Lionetti, L., Mollica, M. P., Ferraro, M., D’Andrea, E., Mainieri, D., Dulloo, A. G., Liverini, G., & Iossa, S. (2006) · Diabetes · doi:10.2337/db06-0312 · Cited by 72 · see citing works

Skeletal muscle subsarcolemmal mitochondrial dysfunction in high-fat fed rats exhibiting impaired glucose homeostasis

Lionetti, L., Mollica, M. P., Crescenzo, R., D’Andrea, E., Ferraro, M., Bianco, F., Liverini, G., & Iossa, S. (2007) · International Journal of Obesity · doi:10.1038/sj.ijo.0803636 · Cited by 70 · see citing works

Fatty acid transport and FAT/CD36 are increased in red but not in white skeletal muscle of ZDF rats

Chabowski, A., Chatham, J. C., Tandon, N. N., Calles-Escandón, J., Glatz, J. F. C., Luiken, J. J. F. P., & Bonen, A. (2006) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.00096.2006 · Cited by 69 · see citing works

Alterations in Skeletal Muscle Fatty Acid Handling Predisposes Middle-Aged Mice to Diet-Induced Insulin Resistance

Koonen, D. P. Y., Sung, M. M. Y., Kao, C. K., Dolinsky, V. W., Koves, T. R., Ilkayeva, O., Jacobs, R. L., Vance, D. E., Light, P. E., Muoio, D. M., et al. (2010) · Diabetes · doi:10.2337/db09-1142 · Cited by 65 · see citing works

Cardiac and skeletal muscle fatty acid transport and transporters and triacylglycerol and fatty acid oxidation in lean and Zucker diabetic fatty rats

Bonen, A., Holloway, G. P., Tandon, N. N., Han, X.-X., McFarlan, J. T., Glatz, J. F. C., & Luiken, J. J. F. P. (2009) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.90820.2008 · Cited by 60 · see citing works

In Vino Veritas: A Tale of Two Sirt1s?

Koo, S., & Montminy, M. (2006) · Cell · doi:10.1016/j.cell.2006.11.034 · Cited by 60 · see citing works

Changes in FAT/CD36, UCP2, UCP3 and GLUT4 gene expression during lipid infusion in rat skeletal and heart muscle

Vettor, R., Fabris, R., Serra, R., Lombardi, A., Tonello, C., Granzotto, M., Marzolo, M., Carruba, M. O., Ricquier, D., Federspil, G., et al. (2002) · International Journal of Obesity · doi:10.1038/sj.ijo.0802005 · Cited by 57 · see citing works

Grapes versus gluttony

Kaeberlein, M. R., & Rabinovitch, P. S. (2006) · Nature · doi:10.1038/nature05308 · Cited by 42 · see citing works

Lipid overaccumulation and drastic insulin resistance in adult catch-up growth rats induced by nutrition promotion after undernutrition

Chen, L., Hu, X., Zheng, J., Kong, W., Zhang, H., Yang, W.-H., Zhu, S.-P., Zeng, T., Zhang, J., Deng, X., et al. (2010) · Metabolism · doi:10.1016/j.metabol.2010.05.014 · Cited by 22 · see citing works

Increases in energy intake, insulin resistance and stress in rats before Wenchuan earthquake far from the epicenter

Chen, L., Hu, X., Zheng, J., Zhang, H., Kong, W., Yang, W.-H., Zeng, T., Zhang, J., & Yue, L. (2010) · Experimental Biology and Medicine · doi:10.1258/ebm.2010.010042 · Cited by 11 · see citing works

Natural products for the treatment of type 2 diabetes mellitus: Pharmacology and mechanisms

Xu, L., Li, Y., Dai, Y., & Peng, J. (2018) · Pharmacological Research · doi:10.1016/j.phrs.2018.01.015 · Cited by 452 · see citing works

Resveratrol and diabetes: from animal to human studies.

Szkudelski, T., & Szkudelska, K. (2015) · Biochimica et Biophysica Acta · doi:10.1016/j.bbadis.2014.10.013 · Cited by 322 · see citing works

Dietary polyphenols as antidiabetic agents: Advances and opportunities

Sun, C., Zhao, C., Çapanoğlu, E., Paoli, P., Simal‐Gándara, J., Ramkumar, K. M., Wang, S., Buleu, F. N., Pah, A.-M., Turi, V., et al. (2020) · Food Frontiers · doi:10.1002/fft2.15 · Cited by 303 · see citing works

Resveratrol: from enhanced biosynthesis and bioavailability to multitargeting chronic diseases

Pannu, N., & Bhatnagar, A. (2018) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2018.11.075 · Cited by 289 · see citing works

Butyrate alleviates high fat diet-induced obesity through activation of adiponectin-mediated pathway and stimulation of mitochondrial function in the skeletal muscle of mice

Hong, J., Jia, Y., Pan, S., Jia, L., Li, H., Han, Z., Cai, D., & Zhao, R. (2016) · Oncotarget · doi:10.18632/oncotarget.11267 · Cited by 236 · see citing works

Food Polyphenols and Type II Diabetes Mellitus: Pharmacology and Mechanisms

Naz, R., Saqib, F., Awadallah, S. M., Wahid, M., Latif, M. F., Iqbal, I., & Mubarak, M. S. (2023) · Molecules · doi:10.3390/molecules28103996 · Cited by 175 · see citing works

Resveratrol Upregulates Nrf2 Expression To Attenuate Methylglyoxal-Induced Insulin Resistance in Hep G2 Cells

Cheng, A.-S., Cheng, Y., Chiou, C.-H., & Chang, T.-L. (2012) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf302831d · Cited by 155 · see citing works

Resveratrol ameliorates hepatic metaflammation and inhibits NLRP3 inflammasome activation

Yang, S. J., & Lim, Y. (2014) · Metabolism · doi:10.1016/j.metabol.2014.02.003 · Cited by 141 · see citing works

Resveratrol and obesity: can resveratrol relieve metabolic disturbances?

de Ligt, M., Timmers, S., & Schrauwen, P. (2015) · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · doi:10.1016/j.bbadis.2014.11.012 · Cited by 135 · see citing works

Thermogenesis is involved in the body-fat lowering effects of resveratrol in rats

Alberdi, G., Rodríguez, V. M., Miranda, J., Macarulla, M. T., Churruca, I., & Portillo, M. P. (2013) · Food Chemistry · doi:10.1016/j.foodchem.2013.03.085 · Cited by 125 · see citing works

Resveratrol in Treating Diabetes and Its Cardiovascular Complications: A Review of Its Mechanisms of Action

Su, M., Zhao, W., Xu, S., & Weng, J. (2022) · Antioxidants · doi:10.3390/antiox11061085 · Cited by 120 · see citing works

Resveratrol restores the circadian rhythmic disorder of lipid metabolism induced by high-fat diet in mice

Sun, L., Wang, Y., Song, Y., Cheng, X., Xia, S., Rahman, M. R. T., Shi, Y., & Le, G. (2015) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2015.01.072 · Cited by 111 · see citing works

Resveratrol ameliorates metabolic disorders and insulin resistance in high-fat diet-fed mice

Gong, L., Guo, S., & Zou, Z. (2019) · Life Sciences · doi:10.1016/j.lfs.2019.117212 · Cited by 96 · see citing works

Efficacy and risk profile of anti-diabetic therapies: Conventional vs traditional drugs—A mechanistic revisit to understand their mode of action

Gupta, P., Bala, M., Gupta, S. K., Dua, A., Dabur, R., Injeti, E. R., & Mittal, A. (2016) · Pharmacological Research · doi:10.1016/j.phrs.2016.09.029 · Cited by 90 · see citing works

Anti-obesity effect of resveratrol-amplified grape skin extracts on 3T3-L1 adipocytes differentiation

Zhang, X.-H., Huang, B., Choi, S.-K., & Seo, J. (2012) · Nutrition Research and Practice · doi:10.4162/nrp.2012.6.4.286 · Cited by 73 · see citing works

Clinical relevance of epigenetics in the onset and management of type 2 diabetes mellitus

Sommese, L., Zullo, A., Mancini, F. P., Fabbricini, R., Soricelli, A., & Claudio Napoli, A. (2017) · Epigenetics · doi:10.1080/15592294.2016.1278097 · Cited by 73 · see citing works

Resveratrol vs. calorie restriction: Data from rodents to humans

Lam, Y. Y., Peterson, C. M., & Ravussin, É. (2013) · Experimental Gerontology · doi:10.1016/j.exger.2013.04.005 · Cited by 72 · see citing works

Acetylation and deacetylation—novel factors in muscle wasting

Alamdari, N., Aversa, Z., Castillero, E., & Hasselgren, P.-O. J. (2012) · Metabolism · doi:10.1016/j.metabol.2012.03.019 · Cited by 71 · see citing works

Resveratrol Improves Glycemic Control in Type 2 Diabetic Obese Mice by Regulating Glucose Transporter Expression in Skeletal Muscle and Liver

Yonamine, C. Y., Pinheiro-Machado, E., Michalani, M. L. E., Alves-Wagner, A. B., Esteves, J. V. D. C., Freitas, H. S., & Machado, U. F. (2017) · Molecules · doi:10.3390/molecules22071180 · Cited by 71 · see citing works

SIRT1 attenuates high glucose-induced insulin resistance via reducing mitochondrial dysfunction in skeletal muscle cells

Zhang, H., Ma, X., Wu, L., Zhao, Y., Zhang, P.-Y., Zhang, Y., Shao, M., Liu, F., Li, F., & Qin, G.-J. (2015) · Experimental Biology and Medicine · doi:10.1177/1535370214557218 · Cited by 60 · see citing works

The Effect of Resveratrol Supplementation on Cardio‐Metabolic Risk Factors in Patients with Type 2 Diabetes: A Randomized, Double‐Blind Controlled Trial

Abdollahi, S., Salehi‐Abargouei, A., Toupchian, O., Sheikhha, M. H., Fallahzadeh, H., Rahmanian, M., Tabatabaie, M., & Mozaffari–Khosravi, H. (2019) · Phytotherapy Research · doi:10.1002/ptr.6487 · Cited by 57 · see citing works

Hypoglycaemic and hypolipidaemic activities of sesamin from sesame meal and its ability to ameliorate insulin resistance in KK ‐Ay mice

Hong, L., Wang, Y., Liangliang, C., Han, J., Wang, Q., & Xiaoxiang, Z. (2012) · Journal of the Science of Food and Agriculture · doi:10.1002/jsfa.5974 · Cited by 53 · see citing works

Resveratrol reduces the inflammatory response in adipose tissue and improves adipose insulin signaling in high-fat diet-fed mice

Ding, S., Jiang, J., Wang, Z., Zhang, G., Yin, J., Wang, X., Wang, S., & Yu, Z. (2018) · PeerJ · doi:10.7717/peerj.5173 · Cited by 53 · see citing works

Dietary Polyphenols as Anti-Aging Agents: Targeting the Hallmarks of Aging

Liu, Y., Fang, M., Tu, X., Mo, X., Zhang, L., Yang, B., Wang, F., Kim, Y., Huang, C., Chen, L., et al. (2024) · Nutrients · doi:10.3390/nu16193305 · Cited by 58 · see citing works

Resveratrol attenuates triglyceride accumulation associated with upregulation of Sirt1 and lipoprotein lipase in 3T3-L1 adipocytes

Imamura, H., Nagayama, D., Ishihara, N., Tanaka, S., Watanabe, R., Watanabe, Y., Sato, Y., Yamaguchi, T., Ban, N., Kawana, H., et al. (2017) · Molecular Genetics and Metabolism Reports · doi:10.1016/j.ymgmr.2017.05.003 · Cited by 48 · see citing works

Targeting sirtuins for the treatment of diabetes

Huynh, F. K., Hershberger, K. A., & Hirschey, M. D. (2013) · Diabetes Management · doi:10.2217/dmt.13.6 · Cited by 47 · see citing works

Both linoleic and α-linolenic acid prevent insulin resistance but have divergent impacts on skeletal muscle mitochondrial bioenergetics in obese Zucker rats

Matravadia, S., Herbst, E. A. F., Jain, S. S., Mutch, D. M., & Holloway, G. P. (2014) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.00032.2014 · Cited by 46 · see citing works

Resveratrol Is Not as Effective as Physical Exercise for Improving Reproductive and Metabolic Functions in Rats with Dihydrotestosterone-Induced Polycystic Ovary Syndrome

Benrick, A., Maliqueo, M. A., Sun, M., Villanueva, J. A., Feng, Y., Ohlsson, C., Dulęba, A. J., & Stener‐Victorin, E. (2013) · Evidence-based Complementary and Alternative Medicine · doi:10.1155/2013/964070 · Cited by 45 · see citing works

Pterostilbene improves glycaemic control in rats fed an obesogenic diet: involvement of skeletal muscle and liver

Gómez‐Zorita, S., Fernández‐Quintela, A., Aguirre, L., Macarulla, M. T., Rimando, A. M., & Portillo, M. P. (2015) · Food & Function · doi:10.1039/c5fo00151j · Cited by 44 · see citing works

Resveratrol enhances HBV replication through activating Sirt1-PGC-1α-PPARα pathway

Shi, Y., Li, Y., Huang, C., Ying, L., Xue, J., Wu, H., Chen, Z., & Yang, Z. (2016) · Scientific Reports · doi:10.1038/srep24744 · Cited by 43 · see citing works

Resveratrol Protects Against Renal Damage via Attenuation of Inflammation and Oxidative Stress in High-Fat-Diet-Induced Obese Mice

Cheng, K., Song, Z., Chen, Y., Li, S., Zhang, Y., Zhang, H., Zhang, L., Wang, C., & Wang, T. Z. (2018) · Inflammation · doi:10.1007/s10753-018-0948-7 · Cited by 43 · see citing works

Resveratrol improves high-fat diet induced insulin resistance by rebalancing subsarcolemmal mitochondrial oxidation and antioxidantion

Haohao, Z., Guijun, Q., Juan, Z., Wen, K., & Lulu, C. (2015) · Journal of Physiology and Biochemistry · doi:10.1007/s13105-015-0392-1 · Cited by 42 · see citing works

SIRT1 activation inhibits hyperglycemia-induced apoptosis by reducing oxidative stress and mitochondrial dysfunction in human endothelial cells

Wang, S., Wang, J., Zhao, A., & Li, J. (2017) · Molecular Medicine Reports · doi:10.3892/mmr.2017.7027 · Cited by 41 · see citing works

Resveratrol primes the effects of physical activity in old mice

Rodríguez-Bies, E., Tung, B. T., Navas, P., & López-Lluch, G. (2016) · British Journal Of Nutrition · doi:10.1017/s0007114516002920 · Cited by 40 · see citing works

Resveratrol improves muscle regeneration in obese mice through enhancing mitochondrial biogenesis

Niu, W., Wang, H., Wang, B., Mao, X., & Du, M. (2021) · The Journal of Nutritional Biochemistry · doi:10.1016/j.jnutbio.2021.108804 · Cited by 39 · see citing works

Resveratrol Preserves Mitochondrial Function, Stimulates Mitochondrial Biogenesis, and Attenuates Oxidative Stress in Regulatory T Cells of Mice Fed a High‐Fat Diet

Wang, B., Sun, J., Ma, Y., Wu, G., Tian, Y., Shi, Y., & Le, G. (2014) · Journal of Food Science · doi:10.1111/1750-3841.12555 · Cited by 39 · see citing works

Role of mitochondrial dysfunction and dysregulation of Ca2+ homeostasis in insulin insensitivity of mammalian cells

Wang, C., Tsai, T., & Wei, Y. (2015) · Annals of the New York Academy of Sciences · doi:10.1111/nyas.12838 · Cited by 38 · see citing works

Complementary Therapy in Polycystic Ovary Syndrome

Aquino, C. I., & Nori, S. L. (2014) · Europe PMC (PubMed Central) · doi:10.14273/unisa-247 · Cited by 37 · see citing works

Submaximal ADP‐stimulated respiration is impaired in ZDF rats and recovered by resveratrol

Smith, B. K., Perry, C. G. R., Herbst, E. A. F., Ritchie, I. R. W., Beaudoin, M., Smith, J. C., Neufer, P. D., Wright, D. C., & Holloway, G. P. (2013) · The Journal of Physiology · doi:10.1113/jphysiol.2013.259226 · Cited by 37 · see citing works

The role of resveratrol in diabetes and obesity associated with insulin resistance

Hoca, M., Becer, E., & Vatansever, H. S. (2021) · Archives of Physiology and Biochemistry · doi:10.1080/13813455.2021.1893338 · Cited by 36 · see citing works

Resveratrol attenuates intermittent hypoxia-induced insulin resistance in rats: Involvement of Sirtuin 1 and the phosphatidylinositol-4,5-bisphosphate 3-kinase/AKT pathway

Wang, Q., Sun, X., Li, X., DONG, X., LI, P., & Zhao, L. (2014) · Molecular Medicine Reports · doi:10.3892/mmr.2014.2762 · Cited by 31 · see citing works

Pioglitazone ameliorates the lowered exercise capacity and impaired mitochondrial function of the skeletal muscle in type 2 diabetic mice

Takada, S., Hirabayashi, K., Kinugawa, S., Yokota, T., Matsushima, S., Suga, T., Kadoguchi, T., Fukushima, A., Homma, T., Mizushima, W., et al. (2014) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2014.06.008 · Cited by 30 · see citing works

Oxidative Stress, Inflammation and Connexin Hemichannels in Muscular Dystrophies

González‐Jamett, A. M., Vásquez, W., Cifuentes-Riveros, G., Martínez-Pando, R., Sáez, J. C., & Cárdenas, A. M. (2022) · Biomedicines · doi:10.3390/biomedicines10020507 · Cited by 29 · see citing works

Sirtuin biology and relevance to diabetes treatment

Dong, X. C. (2012) · Diabetes Management · doi:10.2217/dmt.12.16 · Cited by 29 · see citing works

Mitochondrial Adaptation in Skeletal Muscle: Impact of Obesity, Caloric Restriction, and Dietary Compounds

Jun, L., Tao, Y.-X., Geetha, T., & Babu, J. R. (2024) · Current Nutrition Reports · doi:10.1007/s13668-024-00555-7 · Cited by 27 · see citing works

SIRT1 overexpression in skeletal muscle in vivo induces increased insulin sensitivity and enhanced complex I but not complex II–V functions in individual subsarcolemmal and intermyofibrillar mitochondria

Zhang, H., Qin, G.-J., Li, X., Zhang, Y., Du, P., Zhang, P.-Y., Zhao, Y., & Wu, J. (2015) · Journal of Physiology and Biochemistry · doi:10.1007/s13105-015-0396-x · Cited by 25 · see citing works

The Potential Role of Polyphenols in Modulating Mitochondrial Bioenergetics within the Skeletal Muscle: A Systematic Review of Preclinical Models

Mthembu, S. X. H., Dludla, P. V., Ziqubu, K., Nyambuya, T. M., Kappo, A. P., Madoroba, E., Nyawo, T. A., Nkambule, B. B., Silvestri, S., Muller, C. J. F., et al. (2021) · Molecules · doi:10.3390/molecules26092791 · Cited by 23 · see citing works

Resveratrol attenuates metabolic, sperm, and testicular changes in adult Wistar rats fed a diet rich in lipids and simple carbohydrates

Gregório, B. M., de Oliveira, F., Costa, W., & Sampaio, F. B. (2018) · Asian Journal of Andrology · doi:10.4103/aja.aja_67_18 · Cited by 22 · see citing works

Similar changes in muscle lipid metabolism are induced by chronic high‐fructose feeding and high‐fat feeding in C57 BL /J6 mice

Song, G., Ren, L., Chen, S., Wang, C., Liu, N., Wei, L., Li, F., Sun, W., Peng, L., & Tang, Y. P. (2012) · Clinical and Experimental Pharmacology and Physiology · doi:10.1111/1440-1681.12017 · Cited by 20 · see citing works

Raspberry supplementation reduces lipid accumulation and improves insulin sensitivity in skeletal muscle of mice fed a high-fat diet

Zou, T., Kang, Y., Wang, B., de Avila, J. M., You, J., Zhu, M. J., & Du, ‬. (2019) · Journal of Functional Foods · doi:10.1016/j.jff.2019.103572 · Cited by 20 · see citing works

Antidiabetic bioactive natural products from medicinal plants

Tresina, P. S., Selvam, M. S., Döss, A., & Mohan, V. R. (2022) · Studies in natural products chemistry · doi:10.1016/b978-0-323-91250-1.00004-5 · Cited by 19 · see citing works

Mitochondrial impairment but not peripheral inflammation predicts greater Gulf War illness severity

Golomb, B. A., Baez, R. S., Schilling, J. M., Dhanani, M., Fannon, M. J., Berg, B. K., Miller, B. J., Taub, P. R., & Patel, H. H. (2023) · Scientific Reports · doi:10.1038/s41598-023-35896-w · Cited by 19 · see citing works

Resveratrol as a potential protective compound against skeletal muscle insulin resistance

Bahramzadeh, A., Bolandnazar, K., & Meshkani, R. (2023) · Heliyon · doi:10.1016/j.heliyon.2023.e21305 · Cited by 17 · see citing works

Effects of Early Resveratrol Intervention on Skeletal Muscle Mitochondrial Function and Redox Status in Neonatal Piglets with or without Intrauterine Growth Retardation

Cheng, K., Wang, T., Li, S., Song, Z., Zhang, H., Zhang, L., & Wang, T. Z. (2020) · Oxidative Medicine and Cellular Longevity · doi:10.1155/2020/4858975 · Cited by 17 · see citing works

Non-Genetic-Induced Zebrafish Model for Type 2 Diabetes with Emphasis on Tools in Model Validation

Sanni, O., Fasemore, T., & Nkomozepi, P. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms25010240 · Cited by 13 · see citing works

Adenosine Triphosphate Production of Muscle Mitochondria after Acute Exercise in Lean and Obese Humans

Kras, K. A., Hoffman, N., Roust, L. R., Benjamin, T. R., Filippis, E. A. D., & Katsanos, C. S. (2018) · Medicine & Science in Sports & Exercise · doi:10.1249/mss.0000000000001812 · Cited by 13 · see citing works

Resveratrol Blunts Mitochondrial Loss in Slow and Mixed Skeletal Muscle Phenotypes of Non-Human Primates following a Long-Term High Fat/Sugar Diet

Hyatt, J. K., de Cabo, R., & Mattison, J. A. (2022) · Journal of Dietary Supplements · doi:10.1080/19390211.2022.2039340 · Cited by 13 · see citing works

Synergistic Beneficial Effects of Resveratrol and Diet on High-Fat Diet-Induced Obesity

Alrob, O. A., Al-Horani, R., Altaany, Z., & Nusair, M. B. (2022) · Medicina · doi:10.3390/medicina58091301 · Cited by 12 · see citing works

Application of dietary supplements in the prevention of type 2 diabetes-related cardiovascular complications

Jin, Y., & Arroo, R. (2020) · Phytochemistry Reviews · doi:10.1007/s11101-020-09710-8 · Cited by 11 · see citing works

Garcinoic Acid

Kluge, S., Schubert, M., Schmölz, L., Birringer, M., Wallert, M., & Stefan Lorkowski, A. (2016) · Studies in natural products chemistry · doi:10.1016/b978-0-444-63932-5.00009-7 · Cited by 10 · see citing works

Role of trans-resveratrol in ameliorating biochemical and molecular alterations in obese rats induced by a high fructose/fat diet

Khamis, M. M., Moselhy, S. S., & Rihan, S. (2025) · Scientific Reports · doi:10.1038/s41598-025-91027-7 · Cited by 9 · see citing works

The myokine CCL5 recruits subcutaneous preadipocytes and promotes intramuscular fat deposition in obese mice

Yu, W., Yao, Y., Ye, N., Zhao, Y., Ye, Z., Wei, W., Zhang, L., & Chen, J. (2024) · American Journal of Physiology-Cell Physiology · doi:10.1152/ajpcell.00591.2023 · Cited by 9 · see citing works

Resveratrol‐induced remodelling of myocellular lipid stores: A study in metabolically compromised humans

van Polanen, N., Zacharewicz, E., de Ligt, M., Timmers, S., Moonen‐Kornips, E., Schaart, G., Joris Hoeks, J., Schrauwen, P., & Hesselink, M. K. C. (2021) · Physiological Reports · doi:10.14814/phy2.14692 · Cited by 8 · see citing works

Resveratrol and exercise to treat functional limitations in late life: Design of a randomized controlled trial

Layne, A. S., Krehbiel, L. M., Mankowski, R. T., Anton, S. D., Leeuwenburgh, C., Pahor, M., Sandesara, B. D., Wu, S. S., & Buford, T. W. (2017) · Contemporary Clinical Trials Communications · doi:10.1016/j.conctc.2017.03.002 · Cited by 8 · see citing works

Alternating current electromagnetic field exposure lessens intramyocellular lipid accumulation due to high-fat feeding via enhanced lipid metabolism in mice

Nakanishi, R., Tanaka, M., Nisa, B. U., Shimizu, S., Hirabayashi, T., Tanaka, M., Maeshige, N., Roy, R. R., & Fujino, H. (2023) · PLoS ONE · doi:10.1371/journal.pone.0289086 · Cited by 5 · see citing works

Effects of long-term consumption of sucralose associated with high-fat diet in male mice

Santos, P. S., Ruy, C. C., Caria, C. R. P., & Gambero, A. (2021) · Food & Function · doi:10.1039/d1fo02135d · Cited by 5 · see citing works

The role of expression imbalance between adipose synthesis and storage mediated by PPAR-γ/FSP27 in the formation of insulin resistance in catch up growth

Wang, S.-X., Wei, J.-G., Chen, L., Hu, X., & Kong, W. (2016) · Lipids in Health and Disease · doi:10.1186/s12944-016-0319-z · Cited by 5 · see citing works

Effects of antidiabetic agents on lipid metabolism of skeletal muscle: A narrative review

Xu, M., Lv, D., Wei, H., Li, Z., Jin, S., Liu, Q., Zhang, Y., & Liu, Y. (2025) · Diabetes Obesity and Metabolism · doi:10.1111/dom.16189 · Cited by 4 · see citing works

Specific Compounds Derived from Traditional Chinese Medicine Ameliorate Lipid-Induced Contractile Dysfunction in Cardiomyocytes

Wang, F., Neumann, D., Kapsokalyvas, D., Hoes, M. F., Schianchi, F., Glatz, J. F. C., Nabben, M., & Luiken, J. J. F. P. (2024) · International Journal of Molecular Sciences · doi:10.3390/ijms25158131 · Cited by 3 · see citing works

Licorice flavonoid oil supplementation promotes a reduction of visceral fat in exercised rats

Tanaka, M., Kanazashi, M., Kondo, H., Ishihara, A., & Fujino, H. (2021) · The Journal of Sports Medicine and Physical Fitness · doi:10.23736/s0022-4707.20.11260-x · Cited by 3 · see citing works

Resveratrol: is selectivity opening the key to therapeutic effects?

Lee, S., Mantzoros, C. S., & Kim, Y. (2011) · Metabolism · doi:10.1016/j.metabol.2011.09.015 · Cited by 3 · see citing works

Mitochondrial Dysfunction in Insulin Insensitivity and Type 2 Diabetes and New Insights for Their Prevention and Management

Wang, C., Chi, K.-T., & Wei, Y. (2012) · InTech eBooks · doi:10.5772/52320 · Cited by 2 · see citing works

Modulation of the mitochondrial function with polyphenols and other natural bioactive compounds to treat obesity

Gibert‐Ramos, A., Baselga‐Escudero, L., & Crescenti, A. (2020) · Elsevier eBooks · doi:10.1016/b978-0-12-819621-2.00026-7 · Cited by 2 · see citing works

Fetal Origins of Adult Disease

Friedman, J., & Baker, P. R. (2016) · Elsevier eBooks · doi:10.1016/b978-0-323-35214-7.00015-9 · Cited by 1 · see citing works

Regulation of SIRT1, SIRT3, PGC-1α, and LRP130 in Response to Energetic Stress in Human Skeletal Muscle

Edgett, B. A. (2017) · QSpace (Queen's University Library)

Caracterização da S-nitrosação da SIRT1 no músculo esquelético em modelo experimental de envelhecimento

Lenhare, L. (2014) · doi:10.47749/t/unicamp.2014.937755

Potentiel thérapeutique et mécanismes d'action du resvératrol dans les déficits héréditaires de la chaîne respiratoire

Costa, A. L. (2014) · doi:10.70675/9c80429az9d1dz4db8za682z9d3adddc055a

Mécanisme de l'insulino-résistance lors de la modulation in vivo et in vitro par l'acide nicotinique et les polyphénols

Blond, E. (2012) · theses.fr (ABES) · doi:10.70675/189ac795z9e7az4eb1z9b88z991750b0b668

Single and Combined Supplementation of Resveratrol and Fumaric Acid on Energy Metabolism of Litopenaeus vannamei

Souza, J. P., Ramírez, J. R. B., Gomes, R. M. M., Araújo, A. C. D. S., Wasielesky, W., Tesser, M. B., Caldas, S. S., & Monserrat, J. M. (2026) · Animals · doi:10.3390/ani16152338

Resveratrol as a Bioactive Compound for Edible Fish Muscle Quality: Emerging Evidence, Putative Mechanisms, and Future Perspectives

Yu, X.-Z., Yu, Y., Lin, J., Jin, J.-C., & Liu, Z. (2026) · Foods · doi:10.3390/foods15162804

Resveratrol improves high-fat diet induced insulin resistance by rebalancing subsarcolemmal mitochondrial oxidation and antioxidantion

Haohao, Z., Guijun, Q., Juan, Z., Wen, K., & Lulu, C. (2015) · Journal of Physiology and Biochemistry · doi:10.1007/s13105-015-0392-1 · Cited by 42 · see citing works

Resveratrol ameliorates high-fat diet-induced insulin resistance and fatty acid oxidation via ATM-AMPK axis in skeletal muscle.

Yj, Z., Zhao, H., Dong, L., Yf, Z., Hy, X., Hj, M., & Gy, S. (2019) · PubMed · doi:10.26355/eurrev_201910_19315 · Cited by 29 · see citing works

Resveratrol ameliorates high‑fat diet‑induced insulin resistance via the DDIT4/mTOR pathway in skeletal muscle

Pan, X., Xue, G., Zhao, M., Xiang, Z.-P., Liu, D., Duan, Z., & Wang, C. (2025) · Biomedical Reports · doi:10.3892/br.2025.1977 · Cited by 3 · see citing works

Resveratrol supplementation restores high-fat diet-induced insulin secretion dysfunction by increasing mitochondrial function in islet

Kong, W., Chen, L., Zheng, J., Zhang, H., Hu, X., Zeng, T., & Hu, D. (2014) · Experimental Biology and Medicine · doi:10.1177/1535370214548998 · Cited by 22 · see citing works

Resveratrol Alleviates Lipid‐Induced Insulin Resistance in Lean, But Not Severely Obese, Myotubes

Turner, K., Park, S., Beasley, T., Zheng, D., & Houmard, J. A. (2015) · The FASEB Journal · doi:10.1096/fasebj.29.1_supplement.997.9