Cited by 1,068Obesity, Physical Activity, DietObesity and Health PracticesDiabetes, Cardiovascular Risks, and Lipoproteins

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A 2022 update on the epidemiology of obesity and a call to action: as its twin COVID-19 pandemic appears to be receding, the obesity and dysmetabolism pandemic continues to rage on

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Boutari, Chrysoula, Mantzoros, Christos S.·2022·Metabolism

DOI 10.1016/j.metabol.2022.155217PMC PMC9107388

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Abstract

The WHO just released in May 2022 a report on the state of the obesity pandemic in Europe, stating that 60% of citizens in the area of Europe are either overweight or obese, and highlighting the implications of the obesity pandemic, especially as it interacts with the COVID pandemic to create a twin pandemic, to increase morbidity and mortality. Obesity is a complex disease which has reached pandemic dimensions. The worldwide prevalence of obesity has nearly tripled since 1975, mainly due to the adoption of a progressively more sedentary lifestyle and the consumption of less healthy diets. We first report herein updated prevalence rates of overweight and obesity by sex, age, and region first in Europe, per the WHO report, and then worldwide between 1980 and 2019, as we analyze and present herein the data provided by the Global Burden of Disease Study. The prevalence of obesity is higher in women than in men of any age and the prevalence of both overweight and obesity increases with age and has reached their highest point between the ages of 50 to 65 years showing a slight downward trend afterwards. The age-standardized prevalence of obesity has increased from 4.6% in 1980 to 14.0% in 2019. The American and European region have the highest obesity prevalence and the USA and Russia are the countries with the most obese residents. Given dire implications in terms of comorbidities and mortality, these updated epidemiological findings call for coordinated actions from local and regional governments, the scientific community and individual patients alike, as well as the food industry for the obesity pandemic to be controlled and alleviated. We can hopefully learn from the COVID-19 pandemic, where collaborative efforts worldwide, focused intense work at both the local and global level and well-coordinated leadership have demonstrated that humankind is capable of amazing accomplishments by leveraging science and public health, and that we can finally make strides in terms of understanding and combating the obesity pandemic and its dire comorbidities including diabetes, NAFLD, CVD and obesity associated malignancies.

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BackgroundInfluential
Quinoa (Chenopodium quinoa Willd.) supplemented cafeteria diet ameliorates glucose intolerance in rats
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BackgroundInfluential
REduced‐Carbohydrate intervention for managing Obesity and Reduction of gestational Diabetes ( RECORD ): A randomized controlled feasibility trial
Michalopoulou, M., Jebb, S. A., Mackillop, L. H., Dyson, P. A., Hirst, J. E., Zhu, S., Wire, A., & Astbury, N. M. (2024) · Diabetes Obesity and Metabolism · doi:10.1111/dom.15442 · Cited by 10
“An independent researcher generated the randomization list with 2:1 allocation to intervention: control, using random permuted blocks of 3 and 6.”
Method
GLP1R (glucagon-like-peptide-1 incretin receptor), diabetes and obesity phenotypes: An in silico approach revealed new pathogenic variants
Knihs, V. M., & Filippin-Monteiro, F. B. (2024) · Diabetes & Metabolic Syndrome Clinical Research & Reviews · doi:10.1016/j.dsx.2024.102956 · Cited by 8
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“This is an important result in light of several studies that showed that BMI tends to increase with age (Boutari & Mantzoros, 2022; Chooi et al., 2019; Elia, 2001; Reas et al., 2007).”
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“The World Health Organization reported the current obesity prevalence of more than 20% in adult inhabitants of the American and European regions and warned of an ever-increasing trend toward obesity (Boutari and Mantzoros, 2022).”
Background
Obesity in urban Indonesia: evidence from the 2007 and 2018 Basic Health Research
Ferdina, A. R., Arfines, P. P., & Aryastami, N. K. (2024) · Medical Journal of Indonesia · doi:10.13181/mji.oa.247183 · Cited by 9
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Background
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Metabolic surgery reduces CRC disease progression through circulating bile acid diversion
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“Obesity is a global challenge, affecting hundreds of millions of people worldwide and leading to metabolic disorders like type 2 diabetes, non-alcoholic fatty liver disease, and cardiovascular disease (Blüher, 2019; Boutari and Mantzoros, 2022).”
Validity and reliability of Turkish version of the Adult Eating Behaviour Questionnaire for adult participants
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Background
Recent research advances in metabolism, clinical and experimental
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Self-citation
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Background
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Rerkasem, A., Lyons‐Reid, J., Namwongprom, S., Wongsrithep, S., Mangklabruks, A., Phirom, K., Rerkasem, K., & Derraik, J. G. B. (2024) · Frontiers in Public Health · doi:10.3389/fpubh.2024.1346900 · Cited by 8
Efficacy and Safety of Once-Weekly Subcutaneous Semaglutide in Overweight or Obese Adults: A Systematic Review with Meta-Analysis
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Background

Authors: Boutari, C., & Mantzoros, C. S.
Affiliations: Beth Israel Deaconess Medical Center (US)
Corresponding author: Mantzoros, Christos S.
ORCID: Boutari, Chrysoula
Mantzoros, Christos S.
Venue: Metabolism
Publisher: Elsevier BV
Published: 2022-08
Volume: 133
Pages: 155217
ISSN: 0026-0495 (ISSN-L)
DOI: 10.1016/j.metabol.2022.155217
PMC: PMC9107388
OpenAlex: W4280507423
Cited by: 1,068
References: 53
Citations by year: 2026: 176 · 2025: 331 · 2024: 344 · 2023: 188 · 2022: 27
FWCI: 196.46
Type: journal article
Language: en
Open access: hybrid
doi.org
Licence: cc-by-nc-nd
www.elsevier.com/tdm/userlicense/1.0/ (tdm)
www.elsevier.com/legal/tdmrep-license (tdm)
Locations: Metabolism (publishedVersion, cc-by-nc-nd)
PubMed Central (publishedVersion)
PubMed (publishedVersion)
Topics: Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Obesity, Physical Activity, Diet
Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Obesity and Health Practices
Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes, Cardiovascular Risks, and Lipoproteins
Keywords: obesity, overweight, obesity prevalence, obesity epidemiology, obesity epidemic, COVID-19 pandemic, sex differences in obesity, age-standardized prevalence, Global Burden of Disease Study, sedentary lifestyle, unhealthy diet, obesity-related comorbidities, diabetes mellitus, non-alcoholic fatty liver disease, cardiovascular disease, obesity prevention policy
MeSH terms: COVID-19, Aged, Female, Humans, Male, Middle Aged, Obesity, Body Mass Index, Prevalence, Overweight, Pandemics

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A 2022 update on the epidemiology of obesity and a call to action: as its twin COVID-19 pandemic appears to be receding, the obesity and dysmetabolism pandemic continues to rage on

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