Cited by 1,068Obesity, Physical Activity, DietObesity and Health PracticesDiabetes, Cardiovascular Risks, and Lipoproteins

The DOI matches its Crossref record; 48 of the 53 references it cites were found in a registry or an index.

A 2022 update on the epidemiology of obesity and a call to action: as its twin COVID-19 pandemic appears to be receding, the obesity and dysmetabolism pandemic continues to rage on

Open access

Boutari, Chrysoula, Mantzoros, Christos S.·2022·Metabolism

DOI 10.1016/j.metabol.2022.155217PMC PMC9107388

Open this paper in CoChat — free account Open PDF

Abstract

The WHO just released in May 2022 a report on the state of the obesity pandemic in Europe, stating that 60% of citizens in the area of Europe are either overweight or obese, and highlighting the implications of the obesity pandemic, especially as it interacts with the COVID pandemic to create a twin pandemic, to increase morbidity and mortality. Obesity is a complex disease which has reached pandemic dimensions. The worldwide prevalence of obesity has nearly tripled since 1975, mainly due to the adoption of a progressively more sedentary lifestyle and the consumption of less healthy diets. We first report herein updated prevalence rates of overweight and obesity by sex, age, and region first in Europe, per the WHO report, and then worldwide between 1980 and 2019, as we analyze and present herein the data provided by the Global Burden of Disease Study. The prevalence of obesity is higher in women than in men of any age and the prevalence of both overweight and obesity increases with age and has reached their highest point between the ages of 50 to 65 years showing a slight downward trend afterwards. The age-standardized prevalence of obesity has increased from 4.6% in 1980 to 14.0% in 2019. The American and European region have the highest obesity prevalence and the USA and Russia are the countries with the most obese residents. Given dire implications in terms of comorbidities and mortality, these updated epidemiological findings call for coordinated actions from local and regional governments, the scientific community and individual patients alike, as well as the food industry for the obesity pandemic to be controlled and alleviated. We can hopefully learn from the COVID-19 pandemic, where collaborative efforts worldwide, focused intense work at both the local and global level and well-coordinated leadership have demonstrated that humankind is capable of amazing accomplishments by leveraging science and public health, and that we can finally make strides in terms of understanding and combating the obesity pandemic and its dire comorbidities including diabetes, NAFLD, CVD and obesity associated malignancies.

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

Integrity signals

Registry

Crossref · 10.1016/j.metabol.2022.155217

Cites

48 of 49 references verified1 citation errors · 0 not checkable

Statistics

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

Appropriate body-mass index for Asian populations and its implications for policy and intervention strategies
(2004) · The Lancet · doi:10.1016/s0140-6736(03)15268-3 · Cited by 12,717 · cited 1×
“more central body fat distribution, these populations have [33].”
Health effects of overweight and obesity in 195 countries over 25 years
Collaborators, T. G. 2. O. (2017) · New England Journal of Medicine · doi:10.1056/nejmoa1614362 · Cited by 7,918
Worldwide trends in body-mass index, underweight, overweight, and obesity from 1975 to 2016: a pooled analysis of 2416 population-based measurement studies in 128·9 million children, adolescents, and adults
Abarca-Gómez, L., Abdeen, Z. A., Hamid, Z. A., Abu-Rmeileh, N. M., Acosta-Cazares, B., Acuin, C., Adams, R. J., Aekplakorn, W., Afsana, K., Aguilar-Salinas, C. A., et al. (2017) · The Lancet · doi:10.1016/s0140-6736(17)32129-3 · Cited by 7,482
Obesity: global epidemiology and pathogenesis
Blüher, M. (2019) · Nature Reviews Endocrinology · doi:10.1038/s41574-019-0176-8 · Cited by 5,126 · cited 1×
“In addition, regional differences are largely associated with differences in socioeconomic status [30].”
Case-fatality rate and characteristics of patients dying in relation to COVID-19 in Italy
Onder, G., Rezza, G., & Brusaferro, S. (2020) · JAMA · doi:10.1001/jama.2020.4683 · Cited by 4,171
Body Fatness and Cancer — Viewpoint of the IARC Working Group
Lauby-Secretan, B., Scoccianti, C., Loomis, D., Grosse, Y., Bianchini, F., & Straif, K. (2016) · New England Journal of Medicine · doi:10.1056/nejmsr1606602 · Cited by 3,596 · cited 1×
“Epidemiologic studies have revealed an association between high body mass index (BMI) and an extensive range of chronic diseases such as Non Alcoholic Fatty Liver (NAFL), cardiovascular disease [1,2], diabetes mellitus [1], several malignancies [3,4], musculoskeletal diseases [5,6], chronic kidney disease [1], and men…”
The epidemiology of obesity
Chooi, Y. C., Ding, C., & Magkos, F. (2018) · Metabolism · doi:10.1016/j.metabol.2018.09.005 · Cited by 2,997 · cited 1×
“Obesity in the European region stating that both overweight and obesity rates have reached epidemic proportions across the European Region, where 59% of adults and almost 1 in 3 children are suffering from overweight or obesity [20], we publish this report as an update on the epidemiology of obesity [21].”
The Spirit Level: Why More Equal Societies Almost always do Better
Johnston, R. J. (2009) · Political Geography · doi:10.1016/j.polgeo.2009.10.003 · Cited by 2,054
Separate and combined associations of body-mass index and abdominal adiposity with cardiovascular disease: collaborative analysis of 58 prospective studies
The Emerging Risk Factors Collaboration (2011) · The Lancet · doi:10.1016/s0140-6736(11)60105-0 · Cited by 1,216 · cited 1×
“Epidemiologic studies have revealed an association between high body mass index (BMI) and an extensive range of chronic diseases such as Non Alcoholic Fatty Liver (NAFL), cardiovascular disease [1,2], diabetes mellitus [1], several malignancies [3,4], musculoskeletal diseases [5,6], chronic kidney disease [1], and men…”
Severe obesity, increasing age and male sex are independently associated with worse in-hospital outcomes, and higher in-hospital mortality, in a cohort of patients with COVID-19 in the Bronx, New York
Palaiodimos, L., Kokkinidis, D. G., Li, W., Karamanis, D., Ognibene, J., Arora, S., Southern, W. N., & Mantzoros, C. S. (2020) · Metabolism · doi:10.1016/j.metabol.2020.154262 · Cited by 864
Self-citation

Show all 53 references

Research works printed but not linked: 1

Angelidi, 2021, Novel non-invasive approaches to the treatment of obesity: from pharmacotherapy to gene therapy, Endocr Rev

Sorted by citations

Items 601–700 of 1,001

Effect of Obesity on Aquaporin5 Expression in Human Placental and Uterus Tissues
Kemény, K. K., Kozinszky, Z., Altorjay, Á. T., Kolcsár, B., Surányi, A., & Ducza, E. (2024) · Journal of Clinical Medicine · doi:10.3390/jcm13154490 · Cited by 2
“The global prevalence of obesity almost tripled between 1975 and 2023, primarily as a result of increasingly sedentary lifestyles and the consumption of unhealthy diets, with women being more affected than men [1].”
Background
The Physical Activities in Obesity
Hamasaki, H. (2024) · Springer eBooks · doi:10.1007/978-3-031-62491-9_13 · Cited by 2
The influence of environmental cleanliness on food perceptions
Martins, C. M., Trabold, L., & Hamerman, E. J. (2024) · Nutrition and Health · doi:10.1177/02601060241273602 · Cited by 2
Preoperative nonalcoholic steatohepatitis and resolution of metabolic comorbidities after bariatric surgery
Storms, S., Oberhoff, G. H., Schooren, L., Kroh, A., Koch, A. H., Rheinwalt, K.-P., Vondran, F. W. R., Neumann, U. P., Alizai, P. H., & Schmitz, S. M. (2024) · Surgery for Obesity and Related Diseases · doi:10.1016/j.soard.2024.08.026 · Cited by 2
The Prevalence of Obesity and Metabolic Syndrome among Polish Women without Pre-Existing Cardiovascular Conditions and Diabetes: A Multicenter Study in Poland
Babicki, M. (2024) · Journal of Clinical Medicine · doi:10.3390/jcm13175014 · Cited by 2
“Some data show a greater prevalence of obesity in women, some data indicate that it is more common in men, and some show no differences [13,14].”
Background
The Impact of Increased Body Mass Index on Patient Outcomes and Complications in Microsurgical Lower Extremity Reconstruction
Stanton, E. W., Manasyan, A., Boudiab, E. M., Carey, J. N., & Daar, D. A. (2024) · Microsurgery · doi:10.1002/micr.31231 · Cited by 2
Bariatric and endo-bariatric interventions for diabetes: What is the current evidence?
Mondal, S., Fistus, V. A., & Pappachan, J. M. (2024) · World Journal of Diabetes · doi:10.4239/wjd.v15.i11.2255 · Cited by 2
The Significance of Comprehensive Metabolic Phenotypes in Cancer Risk: A Japan Multi-Institutional Collaborative Cohort Study
Watanabe, T., Tiến, N. V., Katsuura‐Kamano, S., Arisawa, K., Ishizu, M., Unohara, T., Tanaka, K., Shimanoe, C., Nagayoshi, M., Tamura, T., et al. (2024) · Cancer Research Communications · doi:10.1158/2767-9764.crc-24-0249 · Cited by 2
“To the best of our knowledge, the present study is the first to examine the relationships between metabolic phenotypes and total and site-specific cancers in Asia, where even though the prevalence of obesity is lower, its impact on health is likely to be greater than in Europe (30, 31).”
Influential
Association between diet protein score comprising plants to animal protein ratio and body composition in an Iranian population
Amlashi, M. A., Jafarpour, A., Eirdmousa, M. H., Homayounfar, R., Farjam, M., & Askari, A. (2024) · Scientific Reports · doi:10.1038/s41598-024-79982-z · Cited by 2
Molecular Mechanisms of Oxidative Stress-Induced Diseases
Tan, B. L., & Norhaizan, M. E. (2024) · SpringerBriefs in food, health and nutrition · doi:10.1007/978-3-031-75319-0_4 · Cited by 2
Bile acids and incretins as modulators of obesity-associated atherosclerosis
Kirsch, A., Gindlhuber, J., Zabini, D., & Osto, E. (2025) · Frontiers in Cardiovascular Medicine · doi:10.3389/fcvm.2024.1510148 · Cited by 2
The relationship between maternal age, obesity and child mortality: a cross-sectional study using 2013–2014 Demographic and Health Survey in Democratic Republic of the Congo at national, and sub-national levels
Dimbuene, Z. T., Nzuzi, R. M., & Matondo, S. M. (2025) · Public Health Nutrition · doi:10.1017/s1368980024002647 · Cited by 2
“Most epidemiologists trace the origins of obesity back in the 1970s (1) ; during that time, it was mostly confined to developed countries (2,3) .”
Body Weight Changes During Ramadan Intermittent Fasting: A Cross‐Sectional Study of Healthy Adults in Turkey
Mektebi, A., Bozlar, M. A., Kanjo, N., Al-Jebaili, M. M., Nasrallah, Y., Faris, M. E., & Khan, M. A. (2025) · Journal of Nutrition and Metabolism · doi:10.1155/jnme/8851660 · Cited by 2
Genetic factors contributing to the development of metabolic syndrome
Kalashnikova, C. E., Shrayner, E. V., Bystrova, V. I., & Израйлевна, Л. Г. (2025) · Pharmacogenetics and Pharmacogenomics · doi:10.37489/2588-0527-2024-2-5-12 · Cited by 2
Influence of the BMI (<30 kg/m 2 vs. ≥30 kg/m 2 ) on the Surgical Outcome of Osteochondral Lesions of the Talus: Prospective Data from the German Cartilage Registry (KnorpelRegister DGOU)
Richter, A., Altemeier, A., Becher, C., Güllmann, M., Plaaß, C., & Ettinger, S. (2025) · Cartilage · doi:10.1177/19476035241301294 · Cited by 2
Differential Association Between Ten Indices of Insulin Resistance and End-Organ Damage in a Community of African Ancestry in Africa
Woodiwiss, A. J., Norton, G. R., Libhaber, C. D., Sareli, P., & Dessein, P. H. (2025) · Journal of Clinical Medicine · doi:10.3390/jcm14082703 · Cited by 2
Life's Essential 8, Genetic Susceptibility, and the Risk of Age-Related Macular Degeneration: A Prospective Cohort Study
Wang, W.-X., Ren, R. C., Liu, Y., Ye, X., Zhang, R., Li, X., Wang, L., Zhang, Y., Zhang, Y., & Wang, D. (2025) · Investigative Ophthalmology & Visual Science · doi:10.1167/iovs.66.4.54 · Cited by 2
Age-Related Differences in Anthropometric and Lifestyle Factors Linked to Metabolic Syndrome in Women with Overweight and Obesity: A Cross-Sectional Study
Łuszczki, E., Zielińska, M., Oleksy, Ł., Stolarczyk, A., & Dereń, K. (2025) · Diabetes Metabolic Syndrome and Obesity · doi:10.2147/dmso.s520553 · Cited by 3
Clinical Features and Diagnosis of Idiopathic Intracranial Hypertension
Antonio‐Santos, A. A. (2025) · CONTINUUM Lifelong Learning in Neurology · doi:10.1212/con.0000000000001570 · Cited by 2
Maternal Adiposity in the First Trimester Pregnancy as a Predictor of Gestational Diabetes Mellitus
Srisovanna, N., Khwankaew, N., Pruksanusak, N., Chainarong, N., Suntharasaj, T., Suwanrath, C., Pranpanus, S., Petpichetchian, C., & Suksai, M. (2025) · Journal of Ultrasound in Medicine · doi:10.1002/jum.16735 · Cited by 2
Automatic Image Recognition Meal Reporting Among Young Adults: Randomized Controlled Trial
Sahoo, P. K., Chiu, S. Y., Lin, Y., Chen, C., Irianti, D., Chen, H., Sarkar, M., & Liu, Y. (2025) · JMIR mhealth and uhealth · doi:10.2196/60070 · Cited by 3
“In 2022, the World Health Organization [1,2] classified 2.5 billion adults (aged 18 years and older) as overweight and thus susceptible to chronic diseases associated with obesity.”
Influential
Towards a better mouse model of vertical sleeve gastrectomy
Blok, N. B., Evers, S. S., Lewis, A. G., Toure, M. H., Bozadjieva-Kramer, N., Seeley, R. J., & Myronovych, A. (2025) · Surgery for Obesity and Related Diseases · doi:10.1016/j.soard.2025.06.017 · Cited by 2
Causal Relationships Between Abdominal Obesity, Type 2 Diabetes, Fasting Insulin, and Cervical Disc Disorders, Osteoporosis, and Rheumatoid Arthritis: A Mendelian Randomization Study
Tang, H., Zhao, J., Yan, X., Zheng, Z.-Y., Bai, W., Tang, Z., & Liu, X. (2025) · Journal of Multidisciplinary Healthcare · doi:10.2147/jmdh.s529217 · Cited by 2
Impact of Age on Short-Term Results of Laparoscopic Sleeve Gastrectomy
Edin, L., Jean, M., Planche, L., Feigel-Guiller, B., & Abet, E. (2025) · Journal of Laparoendoscopic & Advanced Surgical Techniques · doi:10.1177/10926429251389906 · Cited by 2
Cognitive Behavioural Therapies for Weight-Loss in Adults: A Scoping Review Protocol
Gabucio, L. M. C., Mancheño-Bañón, D., Collado, L. T., Vioqué, J., & de la Hera, M. G. (2023) · Healthcare · doi:10.3390/healthcare11182473 · Cited by 2
“As pointed out in the introduction section, the increase in the prevalence of obesity and being overweight has been accompanied by an increase in non-communicable diseases [38] and, consequently, a rise in premature deaths and increased healthcare costs [39].”
Is Morbid Obesity a Modifiable Risk Factor in Patients Who Have Severe Knee Osteoarthritis and do Not Have a Formal Perioperative Optimization Program?
Botros, M., Guirguis, P. G., Balkissoon, R., Myers, T. G., Thirukumaran, C. P., & Ricciardi, B. F. (2023) · The Journal of Arthroplasty · doi:10.1016/j.arth.2023.09.009 · Cited by 2
Management of Early Postoperative Bleeding After OAGB: A Single-center Experience
Helmy, R. F., Elbanna, M., Zemeity, A. O. E., Abozeid, T. A. O., & Fadl, E. M. A. (2023) · Surgical Laparoscopy Endoscopy & Percutaneous Techniques · doi:10.1097/sle.0000000000001232 · Cited by 2
EVALUATION OF WEIGHT REDUCTION EFFICACY AND SAFETY OF SIBUTRAMIN-CONTAINING DRUGS IN PATIENTS WITH ALIMENTARY OBESITY
Demidova, T. Y., Izmaylova, M. Y., Ушакова, С. Е., Zaslavskaya, K. Y., Odegova, A. A., Попова, В. В., Nevretdinova, M. E., & Bely, P. A. (2022) · Pharmacy & Pharmacology · doi:10.19163/2307-9266-2022-10-3-289-304 · Cited by 2
Overweight followed by obesity have the lowest mortality among patients with systolic or diastolic heart failure independent of comorbidities whereas cachexia has the highest mortalityPreprint
Movahed, M. R., Mineer, A., & Hashemzadeh, M. (2024) · medRxiv · doi:10.1101/2024.01.17.24300813 · Cited by 2
Obesity and Overweight: The “Elephant in the Room” That We can No Longer Ignore: Time to SELECT Treatments
Ferrera, A., Gallo, G., & Volpe, M. (2024) · High Blood Pressure & Cardiovascular Prevention · doi:10.1007/s40292-024-00626-4 · Cited by 2
“The Global Burden of Disease estimates that more than 600 million people worldwide are obese [1].”
Background
Efficacy and safety of tirzepatide in overweight or obese adults without diabetes: systematic review and meta-analysis of randomized controlled trialsPreprint
Liu, L., Nahata, M., Shi, H., Sun, Y., & Xie, M. (2024) · Research Square · doi:10.21203/rs.3.rs-4184273/v1 · Cited by 2
Obesity and Its Management
Sogg, S., Sockalingam, S., Himes, S. M., Penava, S. J., & Reilly-Harrington, N. A. (2024) · Elsevier eBooks · doi:10.1016/b978-0-443-11844-9.00072-2 · Cited by 2
The role of the gluteofemoral adipose tissue in cerebrovascular disease risk: evidence from a mendelian randomization and mediation analysisPreprint
Myserlis, E. P., Georgakis, M. K., Parodi, L., Mayerhofer, E., Rosand, J. M., Banerjee, C., & Anderson, C. D. (2024) · medRxiv · doi:10.1101/2024.08.08.24311685 · Cited by 2
Body Composition Changes with Semaglutide: A Systematic Review and Meta-AnalysisPreprint
Giorelli, G., Mizumoto, M., Sartoretto, S., Giorelli, S., Giorelli, P., Bedin-Pochini, A., Toledo, D. O., Barreto, G., & Saunders, B. (2025) · medRxiv · doi:10.1101/2025.09.29.25336760 · Cited by 2
Glycemic Index of a High Protein and High Fiber Oral Nutritional Supplement Vidaslim®
Gayathri, R., Parkav, K., Kavitha, V., Gayathri, N., Jeevan, R. G., Shobana, S., Sudha, V., Ranjit Unnikrishnan, I., Anjana, R. M., Mohan, V., et al. (2023) · Medical Research Archives · doi:10.18103/mra.v11i3.3576 · Cited by 1
Reduced risk of pneumonia and influenza infection after bariatric surgery: a retrospective cohort study among patients with nondiabetic obesity in Taiwan
Chen, P., Lu, C., Lee, Y., Huang, C.-T., Hsu, C., & Huang, K. (2023) · Surgery for Obesity and Related Diseases · doi:10.1016/j.soard.2023.04.328 · Cited by 1
Facial EMG startle response and self-report reactions after exposure to severely underweight and severely obese body images in individuals with disordered eating: An examination of motivational responses
Dauber, A., & Braden, A. L. (2023) · International Journal of Psychophysiology · doi:10.1016/j.ijpsycho.2023.112249 · Cited by 1
Weight reduction among females undergoing laparoscopic ventral hernia repair: The role of Calcium and Vitamin D3
Almulhim, S., AlNaim, M. M., Khan, A. S., Memon, A. Q., Alarfaj, H. M., Abdulqader, A. A. A., & Al‐Mulhim, A. S. (2024) · Pakistan Journal of Medical Sciences · doi:10.12669/pjms.40.5.9047 · Cited by 1
Association between sleep quality with overweight/obesity and other factors among adults in indonesia post-COVID-19 pandemic
Fadlina, A., & Anwar, K. (2024) · AcTion Aceh Nutrition Journal · doi:10.30867/action.v9i1.1198 · Cited by 2
“Global obesity prevalence is increasing by approximately 2 percentage points per decade (Boutari & Mantzoros, 2022).”
Background
The obesity epidemic in adults and possible preventive measures in the Czech Republic
Müllerová, D., Macková, B., & Nejedlá, M. (2024) · Hygiena · doi:10.21101/hygiena.a1852 · Cited by 1
Exploring the Link between Obesity and Hypothyroidism
Khan, S., Rehman, A., Zubair, M., Shah, N. U. R., & Khan, N. (2024) · Pakistan Journal of Health Sciences · doi:10.54393/pjhs.v5i06.1554 · Cited by 1
Opuntia humifusa stems rich in quercetin and isorhamnetin alleviate insulin resistance in high-fat diet-fed rats
Lee, Y., Choi, Y.-J., Kim, E., Hwang, I. G., & Kim, Y. (2024) · Nutrition Research and Practice · doi:10.4162/nrp.2024.18.4.498 · Cited by 1
“In Europe, a staggering 60% of adults are either overweight or obese [1].”
Background
Impact of Patient- and Surgeon-Related Factors on Weight Loss after Laparoscopic Sleeve Gastrectomy—A Single-Center Study
Wityk, M., Dowgiałło‐Gornowicz, N., & Bobowicz, M. (2024) · Medicina · doi:10.3390/medicina60091450 · Cited by 1
Microbiome-Targeted Therapies: Enhancing Resilience in Metabolic Disorders
Janiad, S., & Rehman, K. (2024) · Springer eBooks · doi:10.1007/978-981-97-3790-1_13 · Cited by 1
Utility of the Non-Alcoholic Fatty Liver Disease Fibrosis Score in the Evaluation of Individuals with Medically-Complicated Obesity: A Retrospective Study
Nath, A., Shope, T. R., Pardo, I., & Koch, T. R. (2024) · The International Journal of Gastroenterology and Hepatology Diseases · doi:10.2174/0126662906296409240826050717 · Cited by 1
DISH4U A Crowd Source App for Guiding Users Towards Healthy Food
Määttä, T., Holmi, E., Rostami, M., & Oussalah, M. (2024) · IEEE International Conference on Big Data (BigData) · doi:10.1109/bigdata62323.2024.10825669 · Cited by 1
The association between the health promotion levy and employment in South Africa: an interrupted time series analysis
Dare, C., Boachie, M. K., Goldstein, S., & Thsehla, E. (2025) · BMC Nutrition · doi:10.1186/s40795-025-01012-6 · Cited by 1
“The global prevalence of obesity nearly tripled since 1975 and is expected to increase further in the coming decades [5].”
Biomonitoring of Serum Inorganic Element Concentrations in Morbidly Obese Patients: Impact of Bariatric Surgery
Ramos-Luzardo, Á., Valerón, P. F., Díaz-González, B. V., Zumbado, M. L., Simbaña‐Rivera, K., Bautista-Castaño, I., Ruiz‐Suárez, N., Hernández-García, E., Cornejo-Torre, J., Luzardo, O. P., et al. (2025) · Toxics · doi:10.3390/toxics13030152 · Cited by 1
“According to the World Health Organization, 60% of European adults are overweight or obese [16].”
Association of loss of visceral adipose tissue after concurrent chemoradiotherapy with poor survival in patients with head and neck squamous cell carcinoma
Lee, S. M., Jo, I. Y., Park, J. H., Kim, M., Choi, H. J., Lee, J. W., & Jang, S. J. (2025) · Nutrition · doi:10.1016/j.nut.2025.112775 · Cited by 1
Isotemporal substitution of sedentary time with physical activity and sleeping time: associations with body composition among individuals with prediabetes
Torres-Carballo, M., Galmes-Panades, A. M., Arias-Fernández, M., Huguet-Torres, A., Abbate, M., Fresneda, S., Sánchez-Rodríguez, C., Yáñez, A. M., & Bennasar‐Veny, M. (2025) · Frontiers in Sports and Active Living · doi:10.3389/fspor.2025.1579962 · Cited by 1
A systematic review of patient and clinician experiences of bariatric tourism
Carey, C., James, S. H., & Jaunoo, S. (2025) · Annals of The Royal College of Surgeons of England · doi:10.1308/rcsann.2025.0020 · Cited by 1
“3,8 36 Improving these aspects of bariatric care in the UK recommending and managing bariatric surgical patients as NICE.”
An Ongoing Dilemma Amid Obesity Pandemic: Is Obesity Surgery Feasible in Turkish Adolescents? A Multicenter Study
Savas, O. A., Pekşen, Ç., Yıldırak, M. K., Şen, O., Aktokmakyan, T. V., Arslan, E., Erol, V., Türkçapar, A. G., Banlı, O., & Sümer, A. (2025) · Journal of Laparoendoscopic & Advanced Surgical Techniques · doi:10.1089/lap.2024.0086 · Cited by 1
Adiposity-Based Chronic Disease
Garvey, W. T. (2025) · Springer eBooks · doi:10.1007/978-3-031-82888-1_2 · Cited by 1
Association between living arrangement and psychological well-being among patients with major depressive disorder: the moderating role of body mass index
Wen, C., Liu, Y., Li, Y., Chen, R., Zhao, H., Zhang, X., Zhuang, X., Liao, Y., Hao, J., Chen, Y., et al. (2025) · BMC Psychiatry · doi:10.1186/s12888-025-06947-5 · Cited by 1
“Individuals with abnormal BMI are more likely to develop physical comorbidities such as osteoporosis, type 2 diabetes, and cardiovascular disease [57].”
Evaluation of Physical Activity, Dietary Habits, and Income as Determinants of Health in European Continental Countries: A Data Envelopment Analysis Approach
Sarı, F., Akbulut, F., & Arıbaş, Z. (2025) · Ergoterapi ve Rehabilitasyon Dergisi · doi:10.30720/ered.1524818 · Cited by 1
“Previous studies have linked physical activity, dietary habits, and income with obesity and depression symptoms, emphasizing the importance of addressing these factors (Singh, Olds, Curtis et al., 2023; Tapias, Oyamada-Otani, Correa-Vasques et al., 2021; Boutari & Mantzoros, 2022).”
A proposal for a fat mass index criterion for the assessment of sarcopenic obesity in the community-dwelling older women
Pérez‐Ros, P., Flor-Rufino, C., Fonfría-Vivas, R., Pablos, A., Barrachina-Igual, J., & Martínez‐Arnau, F. M. (2025) · Clinical Nutrition ESPEN · doi:10.1016/j.clnesp.2025.05.033 · Cited by 1
Role of oral probiotic supplementation on gut permeability in obesity: A systematic review of randomized controlled trials
Athiyyah, A. F., Nindya, T. S., Ranuh, R. G., Darma, A., Sumitro, K. R., Rejeki, P. S., Djuari, L., Sudarmo, S. M., & Agustina, R. (2025) · Food Hydrocolloids for Health · doi:10.1016/j.fhfh.2025.100225 · Cited by 1
A mediation analysis assessing if interleukin-6 mediates the association between obesity and new-onset type-2-diabetes
Carris, N. W., Mhaskar, R. S., Coughlin, E. C., Bracey, E., Yadav, H., Halade, G. V., & Valente, M. J. (2025) · Journal of Diabetes and its Complications · doi:10.1016/j.jdiacomp.2025.109110 · Cited by 1
Pregnancy Outcomes After One Anastomosis Gastric Bypass
Rottenstreich, A., Elazary, R., Ben‐Porat, T., Dagan, S. S., Beglaibter, N., & Grinbaum, R. (2025) · Obesity Surgery · doi:10.1007/s11695-025-08006-0 · Cited by 2
“Its worldwide prevalence has nearly tripled in the last four decades, with the American and European regions having the highest rates [1, 2].”
Metabolic Scarring: The Persistent Impact of Past Obesity on Long‐Term Metabolic Health Despite Weight Loss
Hemade, A., & Salameh, P. (2025) · Endocrinology Diabetes & Metabolism · doi:10.1002/edm2.70086 · Cited by 1
Profiling the metabolome of older adults who live with overweight/obesity and undiagnosed cognitive impairment
Alvarez, K. L. F., Ortiz-Manrique, M. M., Dávila-Del-Carpio, G., Peralta-Mestas, A., & Cardenas, C. L. L. (2025) · Neuroscience · doi:10.1016/j.neuroscience.2025.07.037 · Cited by 1
Gender Differences in Quality of Life and Depression Among Post-bariatric Surgery Patients
Monga, V., & Chauhan, M. (2025) · Annals of Neurosciences · doi:10.1177/09727531251352630 · Cited by 1
What You See Is Not What You Get: Food Advertising Amidst the Global Overweight and Obesity Pandemic
Ocokoljić, M. (2025) · Journal of Marketing and Consumer Behaviour in Emerging Markets · doi:10.7172/2449-6634.jmcbem.2025.1.2 · Cited by 1
Obesity duration is linked to bariatric surgery outcomes via adipose tissue response
Sánchez-Ceinos, J., Townsend, B. C., Tercero‐Alcázar, C., López‐Alcalá, J., Ortea, I., Morales‐Conde, S., Cunill, J. L. P., García-Luna, P. P., Cano, D. A., Malagón, M. M., et al. (2025) · Journal of Endocrinology · doi:10.1530/joe-25-0013 · Cited by 1
The inhibitor VB-87531 synergizes with tirzepatide and semaglutide for greater weight loss in DIO mice
Corbalan, J. J., Petronella, B. A., Huang, C., Beasley, J. R., Merritt, J. R., Mugrage, B., & Nickels, J. T. (2025) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2025.152360 · Cited by 1
Colorectal natural orifice specimen extraction surgery in an Asian cohort: does obesity matter?
Seow‐En, I., Ng, W. K. D., Villanueva, M. E. P., & Tan, E. (2025) · Minerva Surgery · doi:10.23736/s2724-5691.25.10857-5 · Cited by 1
De novo pulmonary vein isolation in obese vs nonobese patients under deep sedation: Does obesity increase procedure complexity?
Maslova, V., Ahrens, M., Rosenthal, O., Bau, T., Magerfleisch, P., Moser, F., Zaman, A., Saad, M. F., Spehlmann, M. E., Frank, D., et al. (2025) · Heart Rhythm O2 · doi:10.1016/j.hroo.2025.06.024 · Cited by 2
Glucagon-like peptide-1 receptor agonists inhibit the progression of malignant pleural effusion in obese mice by regulating the metabolism of pleural effusion
Shao, M., Dong, S., Chen, Q., Wei, R.-Q., & Yi, F. (2025) · Journal of Translational Medicine · doi:10.1186/s12967-025-06875-8 · Cited by 2
“Type 2 diabetes mellitus (T2DM) is a prevalent endocrine system disease characterized by hyperglycemia resulting from insufficient insulin secretion and/or insulin resistance, often accompanied by obesity [1, 2].”
The Adipose Tissue-Derived Secretome (ADS) in Obesity Uniquely Regulates the Na-Glucose Transporter SGLT1 in Intestinal Epithelial Cells
Wellington, V. N. A., & Singh, S. (2025) · Cells · doi:10.3390/cells14161241 · Cited by 2
“The World Health Organization, which defines obesity as a body mass index (BMI) ≥ 30 kg/m 2 and overweight as a BMI ≥ 25 kg/m 2 , reported that in 2022, over 2.5 billion adults were overweight, with 890 million of these living with obesity [2,3].”
Influential
Outcomes of Abdominal Contouring in Patients with and without Weight Loss Surgery: A Propensity-Matched Comparison Study
Amro, C., Ryan, I. A., Jog, A., Broach, R. B., Fischer, J. P., Altieri, M. S., & Azoury, S. C. (2025) · Plastic & Reconstructive Surgery · doi:10.1097/prs.0000000000012384 · Cited by 1
Management of Childhood Obesity: Nutrition and Lifestyle Intervention
Xu, T., Zong, A., Chen, S., Li, Y., Wang, X., Xu, L., & Yue, H. (2025) · Springer eBooks · doi:10.1007/978-981-96-8512-7_8 · Cited by 1
PET/fMRI demonstrates that bariatric surgery may reverse striatal dopaminergic dysfunction in women with obesity
Pais, M. L., Crisóstomo, J., Abrunhosa, A., & Castelo-Branco, M. S. (2025) · Communications Medicine · doi:10.1038/s43856-025-01079-z · Cited by 1
Analysis of the microbiota of pregnant women in relation to weight gain during pregnancy – a pilot study
Kosińska–Kaczyńska, K., Zgliczyńska, M., Krawczyk, D., Piątkowska, M., Bałabas, A., Czarnowski, P., Goryca, K., Glinicki, P., Ostrowski, J., & Żeber‐Lubecka, N. (2025) · Frontiers in Cellular and Infection Microbiology · doi:10.3389/fcimb.2025.1655581 · Cited by 1
Associations of TAS1R2 and TAS2R38 Genetic Variants with Sugar-Sweetened Beverage Intake and Obesity Risk in Kuwaiti Adolescents: A Cross-Sectional Study
Yousef, R., Alkazemi, D. U. Z., Abu‐Farha, M., Abubaker, J. A., Devarajan, S., Rahman, A., & Al‐Mulla, F. (2025) · Children · doi:10.3390/children12091192 · Cited by 1
“Globally, obesity prevalence dramatically increased from 4.6% in 1980 to 14% in 2019 [1].”
Influential
Impact of Concurrent Steatotic Liver Disease and Chronic Hepatitis B on Treatment Response to Nucleos(t)ide Analogs
Chau, A., Li, J., Jun, D. W., Hsu, Y., Toyoda, H., Yeh, M., Watanabe, T., Honda, T., Trinh, H. N., Nozaki, A., et al. (2025) · Journal of Viral Hepatitis · doi:10.1111/jvh.70081 · Cited by 2
Surgical synergy or complication catalyst? Evaluating a meta-analysis of concomitant bariatric surgery and ventral hernia repair
da Silveira, C. A. B., Rasador, A. C. D., Vidotto, L. M., Nogueira, R., Melvin, W. S., Camacho, D. R., & Lima, D. L. (2025) · Surgical Endoscopy · doi:10.1007/s00464-025-12207-0 · Cited by 1
Associations Between Obesity and the Severity of Occupational Allergic Rhinitis: A Cross-Sectional Study
Kacem, I., Moussa, A., Sridi, C., Fki, A., Ajmi, M., Thabet, M., Maâlel, O. E., Maoua, M., Kahloul, M., & Mrizek, N. (2025) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph22101531 · Cited by 1
“This major global public health concern, whose prevalence has tripled since 1975 [13], is multifactorial.”
The impact of body mass index on periodontitis: a cross-sectional study
Vishwanath, S., Gurumurthy, V., Saini, R. S., Alarcón‐Sánchez, M. A., Martínez, S. M. L., Heboyan, A. G., & Muradyan, A. A. (2025) · Therapeutic Advances in Chronic Disease · doi:10.1177/20406223251383319 · Cited by 1
Tracking changes in walkability over time: How our neighborhoods are developing and what it means for health surveillance
Wali, B., Frank, L. D., Rees‐Punia, E., & Patel, A. V. (2025) · Environmental Research · doi:10.1016/j.envres.2025.123039 · Cited by 1
Global trends and risk factors of aortic aneurysm mortality from 1990 to 2021: An analysis of the Global Burden of Disease Study 2021
Câsu, R.-M., Metz, L., Freiholtz, D., Zheng, X., Björck, H. M., & Zheng, X. (2025) · Asian Heart Journal · doi:10.1097/ah9.0000000000000008 · Cited by 1
Predictors of weight reduction effectiveness with liraglutide in diabetes mellitus type 2 patients: a retrospective cohort study
Wangpattanamongkol, P., & Manosroi, W. (2025) · BMC Endocrine Disorders · doi:10.1186/s12902-025-02066-0 · Cited by 1
“Over the past decade, the incidence of overweight and obesity has increased significantly worldwide [1].”
Efficacy of dance movement therapy for weight management of overweight or obese adult patients: protocol for a systematic review and trial sequential meta-analysis
Yu, Y., Yue, H.-Y., Lu, C. D., & Jiang, H. (2025) · Systematic Reviews · doi:10.1186/s13643-025-02962-5 · Cited by 1
“Given the escalating global issue of obesity and over-weight, identifying effective interventions emerged as a critical concern in global public health [1, 2].”
A novel framework to assess the prevention value of a health intervention
Pearson‐Stuttard, J., Treharne, C., King, R., Harper, H., Pokhilenko, I., Gomes, M., Garrison, L. P., Reynoso, R., Skau, J. K. H., & Byrne, K. (2025) · Diabetes Obesity and Metabolism · doi:10.1111/dom.70232 · Cited by 2
“With the rising global prevalence of obesity 16 and association with more than 200 obesity-related complications (ORCs), 17 prevention is becoming increasingly important.”
A systematic review of preclinical studies of medicinal plants found in India targeting obesity
Barbhuiya, P. A., Kalita, S., Pal, G., Ahmed, S., Kumari, P., & Pathak, M. P. (2025) · ASPET Discovery · doi:10.1016/j.aspetd.2025.100017 · Cited by 1
Retrospectively reconstructed body mass index change patterns and their association with frailty among American adults: national health and Nutrition Examination survey 2007-2018
Shi, W., Shi, Y., Park, J., & Wu, S. (2025) · Annals of Medicine · doi:10.1080/07853890.2025.2583749 · Cited by 1
“Since body weight and BMI are dynamic parameters, and there has been an increasing trend of weight gain over the past several decades [8], the effect of different change patterns of BMI over time on the risk of frailty deserves more attention.”
Association between vitamin D deficiency and general and abdominal obesity in older adults: insights from baseline data of the Birjand Longitudinal Aging Study (BLAS)
Varmaghani, M., Tajik, A., Aliabadi, M. M., Mohammadi, M., Shobeiri, N., Soleimanzadeh, M., Fakhrzadeh, H., Payab, M., Ebrahimpour, M., Moudi, M., et al. (2025) · Journal of Diabetes & Metabolic Disorders · doi:10.1007/s40200-025-01784-5 · Cited by 1
Trends in the weight status of adults in Ireland between 1990 and 2024
Donovan, C. M., Buffini, M., Walton, J., Kehoe, L., Kearney, J. M., Flynn, A., Nugent, A. P., & McNulty, B. A. (2025) · European Journal of Nutrition · doi:10.1007/s00394-025-03822-7 · Cited by 1
Enteric microbiome and obesity: a multidimensional narrative review
Barat, B., Ghosh, K., Kulkarni, B. P., Banerjee, P., & Ghosh, K. (2025) · Microbial Genomics · doi:10.1099/mgen.0.001562 · Cited by 1
Assessing Hepatic Steatosis Following Weight Loss in Adolescents with Severe Obesity: A Randomized Controlled Trial
Talib, A., de Boom, F., Roebroek, Y. G. M., Paulus, G. F., Koek, G. H., Robben, S. G. F., Winkens, B., Bouvy, N. D., & van Heurn, E. L. W. (2025) · Children · doi:10.3390/children12121652 · Cited by 1
“The global surge in severe obesity among adolescents has led to a marked increase in comorbid conditions such as type 2 diabetes, hypertension and metabolic dysfunction– associated steatotic liver disease (MASLD), of which hepatic steatosis is a hallmark feature [1,2].”
Association Between Indicators of Nutritional Status and Psychological Distress in Medical Students in Slovakia
Repiská, G., Gurecká, R., Belica, I., Janšáková, K., Babinská, K., Lakatošová, S., Tomova, A., Jasenovec, T., Dukonyová, D., Blaško, F., et al. (2025) · Bratislavské lekárske listy/Bratislava medical journal · doi:10.1007/s44411-025-00443-8 · Cited by 1
“In 2022, 43% of adults aged 18 years and over were overweight, and 16% were living with obesity [7, 9].”
The Effect of Eight-Week Endurance and High-Intensity Interval Training on Leptin, Cortisol and Testosterone Levels in Obese Adolescent Boys
Seifi-Skishahr, F. (2025) · Physical Activity in Children · doi:10.61882/pach.2025.538993.1055 · Cited by 1
Prevalence and factors associated with metabolic dysfunction-associated fatty liver disease in a multiethnic Asian country
Wan, K. S., Rifin, H. M., Yusoff, M. F. M., Chan, W., Ratnam, K. K. Y., Ganapathy, S. S., Hamid, H. A. A., Mohamad, M. M., Noor, N. M., Mustapha, F. I., et al. (2026) · Scientific Reports · doi:10.1038/s41598-025-31737-0 · Cited by 1
Eight-year prevalence and incidence of obesity, high blood glucose and high blood pressure in five African-origin populations: data from the Modeling the Epidemiologic Transition Study
Soepnel, L. M., Conradie, C. M., Geffen, H., Choo-Kang, C., Bovet, P., Viswanathan, B., Bedu-Addo, K., Boateng, P. O., Dei, O. A., Apusiga, K., et al. (2026) · BMJ Public Health · doi:10.1136/bmjph-2025-003427 · Cited by 1
Sex-specific obesity paradox and type 2 myocardial infarction in acute ischemic stroke (AIS) patients
Wang, W., Huang, M., Wu-lin, L. I., Du, X.-W., Li, Y., Lu, Z.-H., Sun, B.-B., Mao, Y., Ma, X.-Y., Han, X., et al. (2026) · Biology of Sex Differences · doi:10.1186/s13293-026-00823-x · Cited by 1
“Obesity is considered a major global health issue [1], significantly increasing the risk of heart and brain-related diseases [2].”
Multi-resolution tone mapping for high dynamic range medical ultrasound images
Vu, T. L. N., Chandran, V., Haberl, C., Scherzer, O., & Binder, J. (2026) · PLoS ONE · doi:10.1371/journal.pone.0340777 · Cited by 1
“Given the global rise in obesity [5], addressing these challenges has become increasingly important.”
Efficacy and Safety of Steamed Ginger Extract for Body Weight and Body Fat Reduction in Overweight Adults: A Randomized, Double-Blind, Placebo-Controlled Clinical Trial
Kwon, J. E., Lee, Y.-G., Kim, I., Bae, J., Kang, S.-C., & Baek, H.-I. (2026) · Nutrients · doi:10.3390/nu18020366 · Cited by 1
“This imbalance results in excessive energy being stored as fat, which can lead to metabolic disturbances and various health complications [3].”
Combined Effects of High-Fat Diet and Chronic Sleep Restriction on Neurophysiological Parameters of Wistar Rats
Guzeev, M. A., Lapshina, K. V., Derkach, K. V., Shpakov, A. O., & Ekimova, I. V. (2026) · Neuroscience and Behavioral Physiology · doi:10.1007/s11055-026-01957-6 · Cited by 1
“Abdominal obesity is one of the most pressing biomedical problems both in Russia and globally [Boutari et al., 2022; Alferova and Musta ﬁ na, 2022].”
Development of the Weight and Emotions Scale (WES)
Kanu, C., Kimel, M., GOETZ, I. A., Neff, L. M., Boye, K. S., Stefan, M., & Jordan, J. B. (2026) · Obesity Science & Practice · doi:10.1002/osp4.70119 · Cited by 1
Physical activity wishes of people with excess body weight - a qualitative systematic review
Christensen, J., Baagøe, C., Muntefering, C., Baygi, F., Tepavicharov, N. K., Holm, S. S., Karstensen, J. K., Brandt, C. J., Nielsen, S. S., & Jessen-Winge, C. (2026) · BMC Public Health · doi:10.1186/s12889-025-25337-w · Cited by 1
“The prevalence of overweight and obesity are increasing worldwide to an extent that is considered a global epidemic [1, 2].”
Impact of Body Weight on Sedation-Related Outcomes in Complex Electrophysiological Interventions
Katov, L., Dupree, C., Teumer, Y., Buss, A., Diofano, F., Bothner, C., Öchsner, W., Rottbauer, W., & Weinmann, K. (2026) · Healthcare · doi:10.3390/healthcare14040517 · Cited by 1
“Since 1975, the number of obese people has almost tripled [6].”

Authors: Boutari, C., & Mantzoros, C. S.
Affiliations: Beth Israel Deaconess Medical Center (US)
Corresponding author: Mantzoros, Christos S.
ORCID: Boutari, Chrysoula
Mantzoros, Christos S.
Venue: Metabolism
Publisher: Elsevier BV
Published: 2022-08
Volume: 133
Pages: 155217
ISSN: 0026-0495 (ISSN-L)
DOI: 10.1016/j.metabol.2022.155217
PMC: PMC9107388
OpenAlex: W4280507423
Cited by: 1,068
References: 53
Citations by year: 2026: 176 · 2025: 331 · 2024: 344 · 2023: 188 · 2022: 27
FWCI: 196.46
Type: journal article
Language: en
Open access: hybrid
doi.org
Licence: cc-by-nc-nd
www.elsevier.com/tdm/userlicense/1.0/ (tdm)
www.elsevier.com/legal/tdmrep-license (tdm)
Locations: Metabolism (publishedVersion, cc-by-nc-nd)
PubMed Central (publishedVersion)
PubMed (publishedVersion)
Topics: Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Obesity, Physical Activity, Diet
Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Obesity and Health Practices
Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes, Cardiovascular Risks, and Lipoproteins
Keywords: obesity, overweight, obesity prevalence, obesity epidemiology, obesity epidemic, COVID-19 pandemic, sex differences in obesity, age-standardized prevalence, Global Burden of Disease Study, sedentary lifestyle, unhealthy diet, obesity-related comorbidities, diabetes mellitus, non-alcoholic fatty liver disease, cardiovascular disease, obesity prevention policy
MeSH terms: COVID-19, Aged, Female, Humans, Male, Middle Aged, Obesity, Body Mass Index, Prevalence, Overweight, Pandemics

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

A 2022 update on the epidemiology of obesity and a call to action: as its twin COVID-19 pandemic appears to be receding, the obesity and dysmetabolism pandemic continues to rage on

Abstract

Overview

Integrity signals

Verification

Claims the paper makes

Claims other papers make about this one

Self-check

Citations

Cites

Cited by

Related

Metadata

Record

About these checks