Neuronal MeCP2 Is Expressed at Near Histone-Octamer Levels and Globally Alters the Chromatin State

Rett syndrome is caused by mutations in X-linked MECP2, encoding methyl-CpG-binding protein 2

Amir, R. E., Van den Veyver, I. B., Wan, M., Tran, C. Q., Francke, U., & Zoghbi, H. Y. (1999) · Nature Genetics · doi:10.1038/13810 · Cited by 4,990 · see citing works

Transcriptional repression by the methyl-CpG-binding protein MeCP2 involves a histone deacetylase complex

Nan, X., Ng, H.-H., Johnson, C. A., Laherty, C. D., Turner, B. M., Eisenman, R. N., & Bird, A. (1998) · Nature · doi:10.1038/30764 · Cited by 3,440 · see citing works

Cellular Scaling Rules for the Brains of Marsupials: Not as “Primitive” as Expected

Santos, S. E. D., Porfírio, J., Cunha, F., Manger, P. R., Tavares, W. C., Pessôa, L. M., Raghanti, M. A., Sherwood, C. C., & Herculano‐Houzel, S. (2017) · Brain Behavior and Evolution · doi:10.1159/000452856 · Cited by 2,651 · see citing works

NeuN, a neuronal specific nuclear protein in vertebratesxs

Mullen, R. J., Buck, C. R., & Smith, A. M. (1992) · Development · doi:10.1242/dev.116.1.201 · Cited by 2,351 · see citing works

MeCP2, a Key Contributor to Neurological Disease, Activates and Represses Transcription

Chahrour, M., Jung, S. Y., Shaw, C., Zhou, X., Wong, S. T. C., Qin, J., & Zoghbi, H. Y. (2008) · Science · doi:10.1126/science.1153252 · Cited by 1,823 · see citing works

Genome-wide High-Resolution Mapping and Functional Analysis of DNA Methylation in Arabidopsis

Zhang, X., Yazaki, J., Sundaresan, A., Cokus, S. J., Chan, S. W.-L., Chen, H., Henderson, I. R., Shinn, P., Pellegrini, M. A., Jacobsen, S. E., et al. (2006) · Cell · doi:10.1016/j.cell.2006.08.003 · Cited by 1,818 · see citing works

A mouse Mecp2-null mutation causes neurological symptoms that mimic Rett syndrome

Guy, J., Hendrich, B., Holmes, M., Martin, J. E., & Bird, A. (2001) · Nature Genetics · doi:10.1038/85899 · Cited by 1,558 · see citing works

MeCP2 is a transcriptional repressor with abundant binding sites in genomic chromatin.

Nan, X.-S., Campoy, F., & Bird, A. (1997) · Cell · doi:10.1016/s0092-8674(00)81887-5 · Cited by 1,403 · see citing works

Purification, sequence, and cellular localization of a novel chromosomal protein that binds to Methylated DNA

Lewis, J. D., Meehan, R. R., Henzel, W. J., Maurer-Fogy, I., Jeppesen, P., Klein, F., & Bird, A. (1992) · Cell · doi:10.1016/0092-8674(92)90610-o · Cited by 1,371 · see citing works

Deficiency of methyl-CpG binding protein-2 in CNS neurons results in a Rett-like phenotype in mice

Chen, R. Z., Akbarian, S., Tudor, M., & Jaenisch, R. (2001) · Nature Genetics · doi:10.1038/85906 · Cited by 1,275 · see citing works

Derepression of BDNF Transcription Involves Calcium-Dependent Phosphorylation of MeCP2

Chen, W. G., Chang, Q., Lin, Y., Meissner, A., West, A. E., Griffith, E. C., Jaenisch, R., & Greenberg, M. E. (2003) · Science · doi:10.1126/science.1086446 · Cited by 1,232 · see citing works

Reversal of Neurological Defects in a Mouse Model of Rett Syndrome

Guy, J., Gan, J., Selfridge, J., Cobb, S., & Bird, A. (2007) · Science · doi:10.1126/science.1138389 · Cited by 1,230 · see citing works

Amount and distribution of 5-methylcytosine in human DNA from different types of tissues or cells

Ehrlich, M., Gama-Sosa, M. A., Huang, L.-H., Midgett, R. M., Kuo, K. C., McCune, R. A., & Gehrke, C. W. (1982) · Nucleic Acids Research · doi:10.1093/nar/10.8.2709 · Cited by 1,039 · see citing works

Brain-Specific Phosphorylation of MeCP2 Regulates Activity-Dependent Bdnf Transcription, Dendritic Growth, and Spine Maturation

Zhou, Z., Hong, E. J., Cohen, S., Zhao, W.-N., Ho, H.-Y. H., Schmidt, L., Chen, W. G., Lin, Y., Savner, E., Griffith, E. C., et al. (2006) · Neuron · doi:10.1016/j.neuron.2006.09.037 · Cited by 877 · see citing works

Mice with Truncated MeCP2 Recapitulate Many Rett Syndrome Features and Display Hyperacetylation of Histone H3

Shahbazian, M. D., Young, J. I., Yuva‐Paylor, L. A., Spencer, C. M., Antalffy, B. A., Noebels, J. L., Armstrong, D. L., Paylor, R. E., & Zoghbi, H. Y. (2002) · Neuron · doi:10.1016/s0896-6273(02)00768-7 · Cited by 760 · see citing works

A fraction of the mouse genome that is derived from islands of nonmethylated, CpG-rich DNA

Bird, A. P., Taggart, M. H., Frommer, M., Miller, O. J., & Macleod, D. (1985) · Cell · doi:10.1016/0092-8674(85)90312-5 · Cited by 714 · see citing works

A Novel CpG Island Set Identifies Tissue-Specific Methylation at Developmental Gene Loci

Illingworth, R. S., Kerr, A. R. W., DeSousa, D., Jørgensen, H. F., Ellis, P., Stalker, J., Jackson, D. K., Clee, C. M., Plumb, R. W., Rogers, J., et al. (2008) · PLoS Biology · doi:10.1371/journal.pbio.0060022 · Cited by 637 · see citing works

Mild overexpression of MeCP2 causes a progressive neurological disorder in mice

Collins, A. L., Levenson, J. M., Vilaythong, A. P., Richman, R., Armstrong, D. L., Noebels, J. L., David Sweatt, J., & Zoghbi, H. Y. (2004) · Human Molecular Genetics · doi:10.1093/hmg/ddh282 · Cited by 626 · see citing works

Loss of silent-chromatin looping and impaired imprinting of DLX5 in Rett syndrome

Horike, S., Cai, S., Miyano, M., Cheng, J., & Kohwi-shigematsu, T. (2004) · Nature Genetics · doi:10.1038/ng1491 · Cited by 585 · see citing works

Identification and functional significance of genes regulated by structurally different histone deacetylase inhibitors

Peart, M. J., Smyth, G. K., van Laar, R. K., Bowtell, D. D. L., Richon, V. M., Marks, P. A., Holloway, A. J., & Johnstone, R. W. (2005) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0500369102 · Cited by 538 · see citing works

Regulation of RNA splicing by the methylation-dependent transcriptional repressor methyl-CpG binding protein 2

Young, J. I., Hong, E. P., Castle, J. C., Crespo-Barreto, J., Bowman, A. B., Rose, M. F., Kang, D., Richman, R., Johnson, J. M., Berget, S., et al. (2005) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0507856102 · Cited by 484 · see citing works

Role of linker histone in chromatin structure and function: H1 stoichiometry and nucleosome repeat length

Woodcock, C. L. F., Skoultchi, A. I., & Fan, Y. (2006) · Chromosome Research · doi:10.1007/s10577-005-1024-3 · Cited by 467 · see citing works

Non–cell autonomous influence of MeCP2-deficient glia on neuronal dendritic morphology

Ballas, N., Lioy, D. T., Grunseich, C., & Mandel, G. (2009) · Nature Neuroscience · doi:10.1038/nn.2275 · Cited by 466 · see citing works

MECP2 is progressively expressed in post-migratory neurons and is involved in neuronal maturation rather than cell fate decisions

Kishi, N., & Macklis, J. D. (2004) · Molecular and Cellular Neuroscience · doi:10.1016/j.mcn.2004.07.006 · Cited by 445 · see citing works

Purification of CpG islands using a methylated DNA binding column

Cross, S. H., Charlton, J. A., Nan, X., & Bird, A. P. (1994) · Nature Genetics · doi:10.1038/ng0394-236 · Cited by 442 · see citing works

Deletions of a differentially methylated CpG island at the SNRPN gene define a putative imprinting control region

Sutcliffe, J. S., Nakao, M., Christian, S. L., Ørstavik, K. H., Tommerup, N., Ledbetter, D. H., & Beaudet, A. L. (1994) · Nature Genetics · doi:10.1038/ng0994-52 · Cited by 413 · see citing works

Integrated epigenomic analyses of neuronal MeCP2 reveal a role for long-range interaction with active genes

Yasui, D. H., Peddada, S., Bieda, M. C., Vallero, R. O., Hogart, A., Nagarajan, R. P., Thatcher, K. N., Farnham, P., & LaSalle, J. M. (2007) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0707442104 · Cited by 381 · see citing works

Expression of MeCP2 in postmitotic neurons rescues Rett syndrome in mice

Luikenhuis, S., Giacometti, E., Beard, C., & Jaenisch, R. (2004) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0401626101 · Cited by 354 · see citing works

DNA Methylation Specifies Chromosomal Localization of MeCP2

Nan, X., Tate, P. H., Li, E., & Bird, A. P. (1996) · Molecular and Cellular Biology · doi:10.1128/mcb.16.1.414 · Cited by 343 · see citing works

Chromatin Compaction by Human MeCP2

Georgel, P. T., Horowitz-Scherer, R. A., Adkins, N., Woodcock, C. L., Wade, P. A., & Hansen, J. C. (2003) · Journal of Biological Chemistry · doi:10.1074/jbc.m305308200 · Cited by 305 · see citing works

Neuropathology of Rett Syndrome

Armstrong, D. D. (2005) · Journal of Child Neurology · doi:10.1177/08830738050200090901 · Cited by 282 · see citing works

Phosphorylation of MeCP2 at Serine 80 regulates its chromatin association and neurological function

Tao, J., Hu, K., Chang, Q., Wu, H., Sherman, N. E., Martinowich, K., Klose, R. J., Schanen, C., Jaenisch, R., Wang, W., et al. (2009) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0811648106 · Cited by 226 · see citing works

Up-regulation of glucocorticoid-regulated genes in a mouse model of Rett syndrome

Nuber, U. A., Kriaučionis, S., Roloff, T. C., Guy, J., Selfridge, J., Steinhoff, C., Schulz, R., Lipkowitz, B., Ropers, H., Holmes, M. C., et al. (2005) · Human Molecular Genetics · doi:10.1093/hmg/ddi229 · Cited by 185 · see citing works

Multiple Modes of Interaction between the Methylated DNA Binding Protein MeCP2 and Chromatin

Tv, N., Shi, X., Ghosh, R. P., Horowitz-Scherer, R. A., Hansen, J. C., & Woodcock, C. L. F. (2006) · Molecular and Cellular Biology · doi:10.1128/mcb.01593-06 · Cited by 178 · see citing works

A Temporal Threshold for Formaldehyde Crosslinking and Fixation

Schmiedeberg, L., Skene, P., Deaton, A. M., & Bird, A. P. (2009) · PLoS ONE · doi:10.1371/journal.pone.0004636 · Cited by 139 · see citing works

DNA Methylation Is Linked to Deacetylation of Histone H3, but Not H4, on the Imprinted Genes Snrpnand U2af1-rs1

Gregory, R. I., Randall, T. E., Johnson, C. A., Khosla, S., Hatada, I., O’Neill, L. P., Turner, B. M., & Feil, R. (2001) · Molecular and Cellular Biology · doi:10.1128/mcb.21.16.5426-5436.2001 · Cited by 136 · see citing works

Quantitative localization of heterogeneous methyl-CpG-binding protein 2 (MeCP2) expression phenotypes in normal and Rett syndrome brain by laser scanning cytometry

LaSalle, J. M. (2001) · Human Molecular Genetics · doi:10.1093/hmg/10.17.1729 · Cited by 134 · see citing works

Cerebellar gene expression profiles of mouse models for Rett syndrome reveal novel MeCP2 targets

Jordan, C., Li, H. H., Kwan, H. C. K., & Francke, U. (2007) · BMC Medical Genetics · doi:10.1186/1471-2350-8-36 · Cited by 126 · see citing works

Elevated methyl-CpG-binding protein 2 expression is acquired during postnatal human brain development and is correlated with alternative polyadenylation

Balmer, D., Goldstine, J., Rao, Y. M., & LaSalle, J. M. (2002) · Journal of Molecular Medicine · doi:10.1007/s00109-002-0396-5 · Cited by 123 · see citing works

Neuropathology of Rett syndrome

Armstrong, D. D. (2002) · Mental Retardation and Developmental Disabilities Research Reviews · doi:10.1002/mrdd.10027 · Cited by 122 · see citing works

Transcription‐dependent neuronal plasticity

Bading, H. (2000) · European Journal of Biochemistry · doi:10.1046/j.1432-1327.2000.01565.x · Cited by 112 · see citing works

Evolutionary conservation of possible functional domains of the human and murine XIST genes

Hendrich, B., Brown, C. J., & Willard, H. F. (1993) · Human Molecular Genetics · doi:10.1093/hmg/2.6.663 · Cited by 106 · see citing works

MeCP2 Behaves as an Elongated Monomer That Does Not Stably Associate with the Sin3a Chromatin Remodeling Complex

Klose, R. J., & Bird, A. P. (2004) · Journal of Biological Chemistry · doi:10.1074/jbc.m408284200 · Cited by 87 · see citing works

Neuronal nuclei and glial nuclei from mammalian cerebral cortex

Pearson, E. C., Bates, D. L., Prospero, T. D., & Thomas, J. O. (1984) · European Journal of Biochemistry · doi:10.1111/j.1432-1033.1984.tb08471.x · Cited by 84 · see citing works

X-linked mental retardation associated with cleft lip/palate maps to Xp11.3-q21.3

Siderius, L. E., Hamel, B. C. J., van Bokhoven, H., de Jager, F., van den Helm, B., Kremer, H., Boer, J. A. H., Ropers, H., & Mariman, E. C. M. (1999) · American Journal of Medical Genetics · doi:10.1002/(sici)1096-8628(19990730)85:3 · Cited by 64 · see citing works

MeCP2 preferentially binds to methylated linker DNA in the absence of the terminal tail of histone H3 and independently of histone acetylation

Ishibashi, T., Thambirajah, A. A., & Ausió, J. (2008) · FEBS Letters · doi:10.1016/j.febslet.2008.03.005 · Cited by 55 · see citing works

Higher order structure in a short repeat length chromatin.

Allan, J., Rau, D. C., Harborne, N., et al. (1984) · The Journal of Cell Biology · doi:10.1083/jcb.98.4.1320 · Cited by 45 · see citing works

Histone methylation: a dynamic mark in health, disease and inheritance

Greer, E. L., & Shi, Y. (2012) · Nature Reviews Genetics · doi:10.1038/nrg3173 · Cited by 2,241 · see citing works

Dysfunction in GABA signalling mediates autism-like stereotypies and Rett syndrome phenotypes

Chao, H.-T., Chen, H., Samaco, R. C., Xue, M., Chahrour, M., Yoo, J., Neul, J. L., Gong, S., Lu, H.-C., Heintz, N., et al. (2010) · Nature · doi:10.1038/nature09582 · Cited by 1,168 · see citing works

MeCP2 binds to 5hmC enriched within active genes and accessible chromatin in the nervous system

Mellén, M., Ayata, P., Dewell, S., Kriaucionis, S., & Heintz, N. (2012) · Cell · doi:10.1016/j.cell.2012.11.022 · Cited by 943 · see citing works

TETonic shift: biological roles of TET proteins in DNA demethylation and transcription

Pastor, W. A., Aravind, L., & Rao, A. (2013) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm3589 · Cited by 897 · see citing works

Synaptic Dysfunction in Neurodevelopmental Disorders Associated with Autism and Intellectual Disabilities

Zoghbi, H. Y., & Bear, M. F. (2012) · Cold Spring Harbor Perspectives in Biology · doi:10.1101/cshperspect.a009886 · Cited by 797 · see citing works

Distribution, recognition and regulation of non-CpG methylation in the adult mammalian brain

Guo, J. U., Su, Y., Shin, J. H., Shin, J., Li, H., Xie, B., Zhong, C., Hu, S., Le, T., Fan, G., et al. (2014) · Nature Neuroscience · doi:10.1038/nn.3607 · Cited by 714 · see citing works

Activity-dependent neuronal signalling and autism spectrum disorder

Ebert, D. H., & Greenberg, M. E. (2013) · Nature · doi:10.1038/nature11860 · Cited by 666 · see citing works

Disruption of DNA-methylation-dependent long gene repression in Rett syndrome

Gabel, H. W., Kinde, B., Stroud, H., Gilbert, C. S., Harmin, D. A., Kastan, N. R., Hemberg, M., Ebert, D. H., & Greenberg, M. E. (2015) · Nature · doi:10.1038/nature14319 · Cited by 569 · see citing works

Methyl-cpG-binding domain proteins: readers of the epigenome

Du, Q., Luu, P.-L., Stirzaker, C., & Clark, S. J. (2015) · Epigenomics · doi:10.2217/epi.15.39 · Cited by 544 · see citing works

Neuronal Activity-Regulated Gene Transcription in Synapse Development and Cognitive Function

West, A. E., & Greenberg, M. E. (2011) · Cold Spring Harbor Perspectives in Biology · doi:10.1101/cshperspect.a005744 · Cited by 532 · see citing works

Restricting retrotransposons: a review

Goodier, J. L. (2016) · Mobile DNA · doi:10.1186/s13100-016-0070-z · Cited by 436 · see citing works

Epigenetic mechanisms in neurological disease

Jakovcevski, M., & Akbarian, S. (2012) · Nature Medicine · doi:10.1038/nm.2828 · Cited by 450 · see citing works

CpG and non-CpG methylation in epigenetic gene regulation and brain function

Jang, H., Shin, W., Lee, J., & Do, J. (2017) · Genes · doi:10.3390/genes8060148 · Cited by 427 · see citing works

Cerebral Organoids Recapitulate Epigenomic Signatures of the Human Fetal Brain

Luo, C., Lancaster, M. A., Castanon, R., Nery, J. R., Knoblich, J. A., & Ecker, J. R. (2016) · Cell Reports · doi:10.1016/j.celrep.2016.12.001 · Cited by 370 · see citing works

Methylation-Dependent and -Independent Genomic Targeting Principles of the MBD Protein Family

Baubec, T., Ivánek, R., Lienert, F., & Schübeler, D. (2013) · Cell · doi:10.1016/j.cell.2013.03.011 · Cited by 365 · see citing works

Pain vulnerability: a neurobiological perspective

Denk, F., McMahon, S. B., & Tracey, I. (2014) · Nature Neuroscience · doi:10.1038/nn.3628 · Cited by 363 · see citing works

Genome-Wide Activity-Dependent MeCP2 Phosphorylation Regulates Nervous System Development and Function

Cohen, S., Gabel, H. W., Hemberg, M., Hutchinson, A. N., Sadacca, L. A., Ebert, D. H., Harmin, D. A., Greenberg, R. S., Verdine, V. K., Zhou, Z., et al. (2011) · Neuron · doi:10.1016/j.neuron.2011.08.022 · Cited by 298 · see citing works

MeCP2 binds to non-CG methylated DNA as neurons mature, influencing transcription and the timing of onset for Rett syndrome

Chen, L., Chen, K., Lavery, L. A., Baker, S. A., Shaw, C. A., Li, W., & Zoghbi, H. Y. (2015) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1505909112 · Cited by 301 · see citing works

HDAC4 Governs a Transcriptional Program Essential for Synaptic Plasticity and Memory

Sando, R., Gounko, N., Pieraut, S., Liao, L., Yates, J., & Maximov, A. (2012) · Cell · doi:10.1016/j.cell.2012.09.037 · Cited by 274 · see citing works

Ketamine and rapid antidepressant action: New treatments and novel synaptic signaling mechanisms

Krystal, J. H., Kavalali, E. T., & Monteggia, L. M. (2024) · Neuropsychopharmacology · doi:10.1038/s41386-023-01629-w · Cited by 262 · see citing works

Reading the unique DNA methylation landscape of the brain: Non-CpG methylation, hydroxymethylation, and MeCP2

Kinde, B., Gabel, H. W., Gilbert, C. S., Griffith, E. C., & Greenberg, M. E. (2015) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1411269112 · Cited by 236 · see citing works

Rett syndrome mutation MeCP2 T158A disrupts DNA binding, protein stability and ERP responses

Goffin, D., Allen, M., Zhang, L., Amorim, M., Wang, I.-T. J., Reyes, A.-R. S., Mercado-Berton, A., Ong, C., Cohen, S., Hu, L., et al. (2012) · Nature Neuroscience · doi:10.1038/nn.2997 · Cited by 226 · see citing works

Maintaining genome stability in the nervous system

McKinnon, P. J. (2013) · Nature Neuroscience · doi:10.1038/nn.3537 · Cited by 229 · see citing works

DNA methylation and childhood maltreatment: From animal models to human studies

Lutz, P.-E., & Turecki, G. (2014) · Neuroscience · doi:10.1016/j.neuroscience.2013.07.069 · Cited by 236 · see citing works

An epigenetic framework for neurodevelopmental disorders: From pathogenesis to potential therapy

Millan, M. J. (2013) · Neuropharmacology · doi:10.1016/j.neuropharm.2012.11.015 · Cited by 229 · see citing works

Activity-dependent phosphorylation of MeCP2 threonine 308 regulates interaction with NCoR

Ebert, D. H., Gabel, H. W., Robinson, N. D., Kastan, N. R., Hu, L. S., Cohen, S., Navarro, A. J., Lyst, M. J., Ekiert, R., Bird, A. P., et al. (2013) · Nature · doi:10.1038/nature12348 · Cited by 227 · see citing works

Epigenetic regulation of the neural transcriptome: the meaning of the marks

Meaney, M. J., & Ferguson-Smith, A. C. (2010) · Nature Neuroscience · doi:10.1038/nn1110-1313 · Cited by 216 · see citing works

Rett syndrome: a neurological disorder with metabolic components

Kyle, S. M., Vashi, N., & Justice, M. J. (2018) · Open Biology · doi:10.1098/rsob.170216 · Cited by 213 · see citing works

Epigenetics and the regulation of stress vulnerability and resilience

Zannas, A. S., & West, A. E. (2014) · Neuroscience · doi:10.1016/j.neuroscience.2013.12.003 · Cited by 211 · see citing works

TALEN-Mediated Gene Mutagenesis in Rhesus and Cynomolgus Monkeys

Liu, H., Chen, Y., Niu, Y., Zhang, K., Kang, Y., Ge, W., Liu, X., Zhao, E., Wang, C., Lin, S., et al. (2014) · Cell Stem Cell · doi:10.1016/j.stem.2014.01.018 · Cited by 200 · see citing works

Role of BDNF epigenetics in activity-dependent neuronal plasticity

Karpova, N. N. (2014) · Neuropharmacology · doi:10.1016/j.neuropharm.2013.04.002 · Cited by 200 · see citing works

A Positive Autoregulatory BDNF Feedback Loop via C/EBPβ Mediates Hippocampal Memory Consolidation

Bambah-Mukku, D., Travaglia, A., Chen, D. Y., Pollonini, G., & Alberini, C. M. (2014) · The Journal of Neuroscience · doi:10.1523/jneurosci.0324-14.2014 · Cited by 145 · see citing works

DNA methylation in the gene body influences MeCP2-mediated gene repression

Kinde, B., Wu, D. Y., Greenberg, M. E., & Gabel, H. W. (2016) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1618737114 · Cited by 118 · see citing works

Dendritic Arborization and Spine Dynamics Are Abnormal in the Mouse Model of<i>MECP2</i>Duplication Syndrome

Jiang, M., Ash, R. T., Baker, S. A., Suter, B., Ferguson, A., Park, J., Rudy, J., Torsky, S. P., Chao, H.-T., Zoghbi, H. Y., et al. (2013) · The Journal of Neuroscience · doi:10.1523/jneurosci.1745-13.2013 · Cited by 129 · see citing works

Experience-Dependent Retinogeniculate Synapse Remodeling Is Abnormal in MeCP2-Deficient Mice

Noutel, J., Hong, Y. K., Leu, B., Kang, E., & Chen, C. (2011) · Neuron · doi:10.1016/j.neuron.2011.03.001 · Cited by 103 · see citing works

Sustained Effects of Rapidly Acting Antidepressants Require BDNF-Dependent MeCP2 Phosphorylation

Kim, J.-W., Autry, A. E., Na, E. S., Adachi, M., Björkholm, C., Kavalali, E. T., & Monteggia, L. M. (2021) · Nature Neuroscience · doi:10.1038/s41593-021-00868-8 · Cited by 113 · see citing works

MeCP2 modulates gene expression pathways in astrocytes

Yasui, D. H., Xu, H., Dunaway, K. W., LaSalle, J. M., Jin, L.-W., & Maezawa, I. (2013) · Molecular Autism · doi:10.1186/2040-2392-4-3 · Cited by 90 · see citing works

RNA sequencing and proteomics approaches reveal novel deficits in the cortex of Mecp2-deficient mice, a model for Rett syndrome

Pacheco, N. L., Heaven, M. R., Holt, L. M., Crossman, D. K., Boggio, K. J., Shaffer, S. A., Flint, D. L., & Olsen, M. L. (2017) · Molecular Autism · doi:10.1186/s13229-017-0174-4 · Cited by 90 · see citing works

MeCP2 co-ordinates liver lipid metabolism with the NCoR1/HDAC3 corepressor complex

Kyle, S. M., Saha, P. K., Brown, H. M., Chan, L. C., & Justice, M. J. (2016) · Human Molecular Genetics · doi:10.1093/hmg/ddw156 · Cited by 84 · see citing works

Somatic LINE-1 retrotransposition in cortical neurons and non-brain tissues of Rett patients and healthy individuals

Zhao, B., Wu, Q., Ye, A. Y., Guo, J., Zheng, X., Yang, X., Yan, L., Liu, Q.-R., Hyde, T. M., Wei, L., et al. (2019) · PLOS Genetics · doi:10.1371/journal.pgen.1008043 · Cited by 83 · see citing works

Recent advances in gene therapy for neurodevelopmental disorders with epilepsy

Turner, T. J., Zourray, C., Schorge, S., & Lignani, G. (2021) · Journal of Neurochemistry · doi:10.1111/jnc.15168 · Cited by 71 · see citing works

Reduction of aberrant NF-κB signalling ameliorates Rett syndrome phenotypes in Mecp2-null mice

Kishi, N., MacDonald, J. L., Ye, J., Molyneaux, B. J., Azim, E., & Macklis, J. D. (2016) · Nature Communications · doi:10.1038/ncomms10520 · Cited by 69 · see citing works

Reversibility of functional deficits in experimental models of Rett syndrome

Cobb, S., Guy, J., & Bird, A. (2010) · Biochemical Society Transactions · doi:10.1042/bst0380498 · Cited by 67 · see citing works

Phosphorylation of MeCP2 at Ser421 Contributes to Chronic Antidepressant Action

Hutchinson, A. N., Deng, J. V., Cohen, S., & West, A. E. (2012) · The Journal of Neuroscience · doi:10.1523/jneurosci.2156-12.2012 · Cited by 53 · see citing works

Neonatal MeCP2 is important for the organization of sex differences in vasopressin expression

Forbes-Lorman, R. M., Rautio, J. J., Kurian, J. R., Auger, A. P., & Auger, C. J. (2012) · Epigenetics · doi:10.4161/epi.7.3.19265 · Cited by 43 · see citing works

DNA Epigenetics in Addiction Susceptibility

Kaplan, G., Xu, H., Abreu, K., & Feng, J. (2022) · Frontiers in Genetics · doi:10.3389/fgene.2022.806685 · Cited by 34 · see citing works

Dysfunction of a SET3-like complex underlies a family of related neurological disorders

Paton, K. M., Alexander-Howden, B., Hare, J. I., Guy, J., Chhatbar, K., Yudina, M., Morris, S. T., Walls, R., Mathieson, T., Spanos, C., et al. (2026) · Nature Communications · doi:10.1038/s41467-026-73227-5

Points of contact between histone H1 and the histone octamer.

Boulikas, T., Wiseman, J. M., & Garrard, W. T. (1980) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.77.1.127 · Cited by 144 · see citing works

Observing Histone H2A.Z Exchange at the Single-Molecule Level

Poyton, M. F., Feng, A., Ranjan, A., et al. (2019) · Biophysical Journal · doi:10.1016/j.bpj.2018.11.2624

A Single High Affinity Binding Site for Histone H1 in a Nucleosome Containing the Xenopus borealis 5 S Ribosomal RNA Gene

Nightingale, K. P., Pruss, D., & Wolffe, A. P. (1996) · Journal of Biological Chemistry · doi:10.1074/jbc.271.12.7090 · Cited by 32 · see citing works

Chaperoning of the histone octamer by the acidic domain of DNA repair factor APLFPreprint

Corbeski, I., Guo, X., Eckhardt, B. V., Fasci, D., Wiegant, W. W., Graewert, M. A., Vreeken, K., Wienk, H., Svergun, D. I., Heck, A. J. R., et al. (2021) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2021.12.24.474097 · Cited by 1 · see citing works

Structure and Function of Tumor Cell Chromatin

Schäfer, W., Tripathi, R. K., Zimmermann, H. J., et al. (1982) · Elsevier eBooks · doi:10.1016/b978-0-12-394380-4.50025-6