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PLEKHM1 Regulates Autophagosome-Lysosome Fusion through HOPS Complex and LC3/GABARAP Proteins
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Depletion of PLEKHM1 significantly reduces the fusion rate between autophagosomes and lysosomes.
“It was previously reported that depletion of PLEKHM1 significantly reduces the fusion rate between autophagosomes and lysosomes16.”
From TMEM55B links autophagy flux, lysosomal repair, and TFE3 activation in response to oxidative stress (2024) · cites this paper as [16]
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Metadata
- Authors
- McEwan, D. G., Popovic, D., Gubas, A., Terawaki, S., Suzuki, H., Stadel, D., Coxon, F. P., Miranda de Stegmann, D., Bhogaraju, S., Maddi, K., Kirchof, A., Gatti, E., Helfrich, M. H., Wakatsuki, S., Behrends, C., Pierre, P., & Dikic, I.
- Venue
- Molecular Cell
- Publisher
- Elsevier BV
- Published
- 2015-01
- Volume
- 57
- Issue
- 1
- Pages
- 39-54
- ISSN
- 1097-2765
- Cited by
- 563
- References
- 14
- Language
- en
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