Insulin rescues amyloid β-induced impairment of hippocampal long-term potentiation

Amyloid plaque core protein in Alzheimer disease and Down syndrome.

Masters, C. L., Simms, G., Weinman, N. A., Multhaup, G., McDonald, B. L., & Beyreuther, K. (1985) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.82.12.4245 · Cited by 4,431 · see citing works

Naturally secreted oligomers of amyloid β protein potently inhibit hippocampal long-term potentiation in vivo

Walsh, D. M., Klyubin, I., Fadeeva, J. V., Cullen, W. K., Anwyl, R., Wolfe, M. S., Rowan, M. J., & Selkoe, D. J. (2002) · Nature · doi:10.1038/416535a · Cited by 4,291 · see citing works

Common structure of soluble amyloid oligomers implies common mechanism of pathogenesis

Kayed, R., Head, E., Thompson, J. L., McIntire, T. M., Milton, S. C., Cotman, C. W., & Glabe, C. G. (2003) · Science · doi:10.1126/science.1079469 · Cited by 4,064 · see citing works

Diffusible, nonfibrillar ligands derived from Aβ _1–42 are potent central nervous system neurotoxins

Lambert, M. P., Barlow, A. K., Chromy, B. A., Edwards, C., Freed, R., Liosatos, M., Morgan, T. E., Rozovsky, I., Trommer, B., Viola, K. L., et al. (1998) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.95.11.6448 · Cited by 3,506 · see citing works

Immunization with amyloid-β attenuates Alzheimer-disease-like pathology in the PDAPP mouse

Schenk, D., Barbour, R., Dunn, W., Gordon, G., Grajeda, H., Guido, T., Hu, K., Huang, J., Johnson-Wood, K., Khan, K., et al. (1999) · Nature · doi:10.1038/22124 · Cited by 3,160 · see citing works

Thioflavine T interaction with synthetic Alzheimer's disease β ‐amyloid peptides: Detection of amyloid aggregation in solution

LeVine, H. (1993) · Protein Science · doi:10.1002/pro.5560020312 · Cited by 2,268 · see citing works

Diabetes mellitus and the risk of dementia: The Rotterdam Study

Ott, A., Stolk, R. P., van Harskamp, F., Pols, H. A. P., Hofman, A., & Breteler, M. M. B. (1999) · Neurology · doi:10.1212/wnl.53.9.1937 · Cited by 2,175 · see citing works

Microtubule-associated protein tau. A component of Alzheimer paired helical filaments.

Grundke, I., Iqbal, K., Quinlan, M., Tung, Y. C., Zaidi, M. S., & Wisniewski, H. M. (1986) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(17)38495-8 · Cited by 1,780 · see citing works

Alzheimer's disease and Down's syndrome: Sharing of a unique cerebrovascular amyloid fibril protein

Glenner, G. G., & Wong, C. W. (1984) · Biochemical and Biophysical Research Communications · doi:10.1016/0006-291x(84)91209-9 · Cited by 1,693 · see citing works

Neuropathology of human Alzheimer disease after immunization with amyloid-β peptide: a case report

Nicoll, J. A. R., Wilkinson, D., Holmes, C., Steart, P., Markham, H., & Weller, R. O. (2003) · Nature Medicine · doi:10.1038/nm840 · Cited by 1,397 · see citing works

Amyloid β-protein (Aβ) assembly: Aβ40 and Aβ42 oligomerize through distinct pathways

Bitan, G., Kirkitadze, M. D., Lomakin, A., Vollers, S. S., Benedek, G. B., & Teplow, D. B. (2002) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.222681699 · Cited by 1,280 · see citing works

Amyloid β-Protein Fibrillogenesis

Walsh, D. M., Lomakin, A., Benedek, G. B., Condron, M. M., & Teplow, D. B. (1997) · Journal of Biological Chemistry · doi:10.1074/jbc.272.35.22364 · Cited by 1,139 · see citing works

Neurotoxicity induces cleavage of p35 to p25 by calpain

Lee, M.-S., Kwon, Y. T., Li, M., Peng, J., Friedlander, R. M., & Tsai, L. (2000) · Nature · doi:10.1038/35012636 · Cited by 1,057 · see citing works

Impaired synaptic plasticity and learning in aged amyloid precursor protein transgenic mice

Chapman, P. F., White, G. L., Jones, M. W., Cooper-Blacketer, D., Marshall, V. J., Irizarry, M., Younkin, L., Good, M. A., Bliss, T. V. P., Hyman, B. T., et al. (1999) · Nature Neuroscience · doi:10.1038/6374 · Cited by 946 · see citing works

Alzheimer's Disease: Molecular Understanding Predicts Amyloid-Based Therapeutics

Selkoe, D. J., & Schenk, D. (2003) · The Annual Review of Pharmacology and Toxicology · doi:10.1146/annurev.pharmtox.43.100901.140248 · Cited by 816 · see citing works

Regulation of AMPA receptor endocytosis by a signaling mechanism shared with LTD

Beattie, E. C., Carroll, R. C., Yu, X., Morishita, W., Yasuda, H., von Zastrow, M., & Malenka, R. C. (2000) · Nature Neuroscience · doi:10.1038/81823 · Cited by 745 · see citing works

Risk of Dementia among Persons with Diabetes Mellitus: A Population-based Cohort Study

Leibson, C. L., Rocca, W. A., Hanson, V. A., Cha, R., Kokmen, E., O'Brien, P. C., & Palumbo, P. J. (1997) · American Journal of Epidemiology · doi:10.1093/oxfordjournals.aje.a009106 · Cited by 700 · see citing works

Structure‐Activity Analyses of β‐Amyloid Peptides: Contributions of the β25–35 Region to Aggregation and Neurotoxicity

Pike, C. J., Walencewicz‐Wasserman, A. J., Kosmoski, J., Cribbs, D. H., Glabe, C. G., & Cotman, C. W. (1995) · Journal of Neurochemistry · doi:10.1046/j.1471-4159.1995.64010253.x · Cited by 699 · see citing works

Regulation of AMPA Receptor–Mediated Synaptic Transmission by Clathrin-Dependent Receptor Internalization

Man, H., Lin, J., Ju, W. H., Ahmadian, G., Liu, L., Becker, L. E., Sheng, M., & Wang, Y. T. (2000) · Neuron · doi:10.1016/s0896-6273(00)81067-3 · Cited by 698 · see citing works

Effects of secreted oligomers of amyloid β‐protein on hippocampal synaptic plasticity: a potent role for trimers

Townsend, M., Shankar, G. M., Mehta, T., Walsh, D. M., & Selkoe, D. J. (2006) · The Journal of Physiology · doi:10.1113/jphysiol.2005.103754 · Cited by 619 · see citing works

Effects of intranasal insulin on cognition in memory-impaired older adults: Modulation by APOE genotype

Reger, M. A., Watson, G. S., Frey, W. H., Baker, L. D., Cholerton, B., Keeling, M. L., Belongia, D., Fishel, M. A., Plymate, S. R., Schellenberg, G. D., et al. (2005) · Neurobiology of Aging · doi:10.1016/j.neurobiolaging.2005.03.016 · Cited by 619 · see citing works

The role of insulin receptor signaling in the brain

Plum, L., Schubert, M., & Brüning, J. C. (2005) · Trends in Endocrinology & Metabolism · doi:10.1016/j.tem.2005.01.008 · Cited by 604 · see citing works

Neuropathology and Pathogenesis of Encephalitis following Amyloid β Immunization in Alzheimer's Disease

Ferrer, I., Boada, M., Guerra, M. L. S., Rey, M. J., & Costa‐Jussà, F. R. (2004) · Brain Pathology · doi:10.1111/j.1750-3639.2004.tb00493.x · Cited by 567 · see citing works

Cerebrospinal fluid and plasma insulin levels in Alzheimer's disease: Relationship to severity of dementia and apolipoprotein E genotype

Craft, S., Peskind, E., Schwartz, M. W., Schellenberg, G. D., Raskind, M., & Porte, D. (1998) · Neurology · doi:10.1212/wnl.50.1.164 · Cited by 560 · see citing works

Distinct molecular mechanisms and divergent endocytotic pathways of AMPA receptor internalization

Lin, J., Ju, W. H., Foster, K. A., Lee, S. H., Ahmadian, G., Wyszynski, M. W., Wang, Y. T., & Sheng, M. (2000) · Nature Neuroscience · doi:10.1038/81814 · Cited by 557 · see citing works

Alzheimer's β-Amyloid Peptides Compete for Insulin Binding to the Insulin Receptor

Xie, L., Helmerhorst, E., Taddei, K., Plewright, B., van Bronswijk, W., & Martins, R. N. (2002) · Journal of Neuroscience · doi:10.1523/jneurosci.22-10-j0001.2002 · Cited by 542 · see citing works

Clearing the brain's amyloid cobwebs

Selkoe, D. J. (2001) · Neuron · doi:10.1016/s0896-6273(01)00475-5 · Cited by 541 · see citing works

Insulin, insulin-degrading enzyme and amyloid-β peptide in Alzheimer's disease: review and hypothesis

Qiu, W. Q., & Folstein, M. F. (2005) · Neurobiology of Aging · doi:10.1016/j.neurobiolaging.2005.01.004 · Cited by 538 · see citing works

Stimulation of β-Amyloid Precursor Protein Trafficking by Insulin Reduces Intraneuronal β-Amyloid and Requires Mitogen-Activated Protein Kinase Signaling

Gasparini, L., Gouras, G. K., Wang, R., Gross, R. S., Beal, M. F., Greengard, P., & Xu, H. (2001) · Journal of Neuroscience · doi:10.1523/jneurosci.21-08-02561.2001 · Cited by 493 · see citing works

Amyloid β protein immunotherapy neutralizes Aβ oligomers that disrupt synaptic plasticity in vivo

Klyubin, I., Walsh, D. M., Lemere, C. A., Cullen, W. K., Shankar, G. M., Betts, V., Spooner, E. T., Jiang, L., Anwyl, R., Selkoe, D. J., et al. (2005) · Nature Medicine · doi:10.1038/nm1234 · Cited by 489 · see citing works

Alzheimer's disease: Aβ, tau and synaptic dysfunction

LaFerla, F. M., & Oddo, S. (2005) · Trends in Molecular Medicine · doi:10.1016/j.molmed.2005.02.009 · Cited by 461 · see citing works

Discovery of a Small Molecule Insulin Mimetic with Antidiabetic Activity in Mice

Zhang, B., Salituro, G., Szalkowski, D., Li, Z., Zhang, Y., Royo, I., Vilella, D., Dı́ez, M. T., Peláez, F., Ruby, C., et al. (1999) · Science · doi:10.1126/science.284.5416.974 · Cited by 456 · see citing works

Activation and redistribution of c‐Jun N‐terminal kinase/stress activated protein kinase in degenerating neurons in Alzheimer's disease

Zhu, X.-W., Raina, A., Rottkamp, C., Aliev, G., Perry, G., Boux, H., & Smith, M. A. (2001) · Journal of Neurochemistry · doi:10.1046/j.1471-4159.2001.00046.x · Cited by 440 · see citing works

Block of Long-Term Potentiation by Naturally Secreted and Synthetic Amyloid β-Peptide in Hippocampal Slices Is Mediated via Activation of the Kinases c-Jun N-Terminal Kinase, Cyclin-Dependent Kinase 5, and p38 Mitogen-Activated Protein Kinase as well as Metabotropic Glutamate Receptor Type 5

Wang, Q., Walsh, D. M., Rowan, M. J., Selkoe, D. J., & Anwyl, R. (2004) · The Journal of Neuroscience · doi:10.1523/jneurosci.1633-03.2004 · Cited by 437 · see citing works

Autoradiographic localization of insulin receptors in rat brain: Prominence in olfactory and limbic areas

Hill, J. M., Lesniak, M. A., Pert, C. B., & Roth, J. (1986) · Neuroscience · doi:10.1016/0306-4522(86)90082-5 · Cited by 413 · see citing works

Macromolecular permeability across the blood-nerve and blood-brain barriers.

Poduslo, J. F., Curran, G. L., & Berg, C. T. (1994) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.91.12.5705 · Cited by 377 · see citing works

p38 Kinase Is Activated in the Alzheimer's Disease Brain

Hensley, K., Floyd, R. A., Zheng, N., Nael, R., Robinson, K. A., Nguyen, X., Pye, Q. N., Stewart, C. A., Geddes, J., Markesbery, W. R., et al. (1999) · Journal of Neurochemistry · doi:10.1046/j.1471-4159.1999.0722053.x · Cited by 373 · see citing works

Impaired learning and LTP in mice expressing the carboxy terminus of the Alzheimer amyloid precursor protein

Nalbantoglu, J. N., Santiago, G. T., Lahsaïni, A., Poirier, J., Goncalves, O., Verge, G. M., Momoli, F., Welner, S. A., Massicotte, G., Julien, J., et al. (1997) · Nature · doi:10.1038/387500a0 · Cited by 334 · see citing works

Transport of Insulin Across the Blood-Brain Barrier: Saturability at Euglycemic Doses of Insulin

Banks, W. A., Jaspan, J. B., Huang, W., & Kastin, A. J. (1997) · Peptides · doi:10.1016/s0196-9781(97)00231-3 · Cited by 318 · see citing works

Does insulin dysfunction play a role in Alzheimer's disease?

Gasparini, L. (2002) · Trends in Pharmacological Sciences · doi:10.1016/s0165-6147(02)02037-0 · Cited by 314 · see citing works

Certain Inhibitors of Synthetic Amyloid β-Peptide (Aβ) Fibrillogenesis Block Oligomerization of Natural Aβ and Thereby Rescue Long-Term Potentiation

Walsh, D. M., Townsend, M., Podlisny, M. B., Shankar, G. M., Fadeeva, J. V., El‐Agnaf, O. M. A., Hartley, D. M., & Selkoe, D. J. (2005) · Journal of Neuroscience · doi:10.1523/jneurosci.4391-04.2005 · Cited by 284 · see citing works

Potential roles of insulin and IGF-1 in Alzheimer's disease

Gasparini, L., & Xu, H. (2003) · Trends in Neurosciences · doi:10.1016/s0166-2236(03)00163-2 · Cited by 275 · see citing works

β-Amyloid Fibrils Activate Parallel Mitogen-Activated Protein Kinase Pathways in Microglia and THP1 Monocytes

McDonald, D. R., Bamberger, M. E., Combs, C. K., & Landreth, G. E. (1998) · Journal of Neuroscience · doi:10.1523/jneurosci.18-12-04451.1998 · Cited by 259 · see citing works

Inhibition of tau phosphorylating protein kinase cdk5 prevents β‐amyloid‐induced neuronal death

Alvarez, A. R., Toro, R., Cáceres, A., & Maccioni, R. B. (1999) · FEBS Letters · doi:10.1016/s0014-5793(99)01279-x · Cited by 228 · see citing works

beta-Amyloid-induced neuronal apoptosis requires c-Jun N-terminal kinase activation

Troy, C. M., Rabacchi, S. A., Xu, Z., Maroney, A. C., Connors, T. J., Shelanski, M. L., & Greene, L. A. (2001) · Journal of Neurochemistry · doi:10.1046/j.1471-4159.2001.t01-1-00218.x · Cited by 223 · see citing works

The cellular and physiological actions of insulin in the central nervous system

Wozniak, M., Rydzewski, B. Z., Baker, S. P., & Raizada, M. K. (1993) · Neurochemistry International · doi:10.1016/0197-0186(93)90062-a · Cited by 207 · see citing works

Tracking Insulin to the Mind

Wickelgren, I. (1998) · Science · doi:10.1126/science.280.5363.517 · Cited by 169 · see citing works

JNK activation is associated with intracellular β-amyloid accumulation

Shoji, M., Iwakami, N., Takeuchi, S., Waragai, M., Suzuki, M., Kanazawa, I., Lippa, C. F., Ono, S., & Okazawa, H. (2000) · Molecular Brain Research · doi:10.1016/s0169-328x(00)00245-x · Cited by 166 · see citing works

Residues 17–20 and 30–35 of beta‐amyloid play critical roles in aggregation

Liu, R., McAllister, C., Lyubchenko, Y. L., & Sierks, M. R. (2003) · Journal of Neuroscience Research · doi:10.1002/jnr.10859 · Cited by 165 · see citing works

Blockade of Long-Term Potentiation by β-Amyloid Peptides in the CA1 Region of the Rat Hippocampus In Vivo

Freir, D. B., Hölscher, C., & Herron, C. E. (2001) · Journal of Neurophysiology · doi:10.1152/jn.2001.85.2.708 · Cited by 153 · see citing works

The Risk of Dementia among Persons with Diabetes Mellitus: A Population‐Based Cohort Studya

Leibson, C. L., Rocca, W. A., Hanson, V., CHA, R., Kokmen, E., O’Brien, P. C., & Palumbo, P. J. (1997) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.1997.tb48496.x · Cited by 152 · see citing works

A Role for Extracellular Adenosine in Time-Dependent Reversal of Long-Term Potentiation by Low-Frequency Stimulation at Hippocampal CA1 Synapses

Huang, C.-C., Liang, Y.-C., & Hsu, K.-S. (1999) · The Journal of Neuroscience · doi:10.1523/jneurosci.19-22-09728.1999 · Cited by 127 · see citing works

An investigation into signal transduction mechanisms involved in insulin‐induced long‐term depression in the CA1 region of the hippocampus

Huang, C., Lee, C., & Hsu, K. (2004) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.2003.02307.x · Cited by 120 · see citing works

Hemoglobin promotes A? oligomer formation and localizes in neurons and amyloid deposits

Wu, C.-Y., LIAO, P., Yu, L., WANG, S., CHEN, S., Wu, C.-Y., & Kuo, Y. (2004) · Neurobiology of Disease · doi:10.1016/j.nbd.2004.08.014 · Cited by 96 · see citing works

Current concepts in therapeutic strategies targeting cognitive decline and disease modification in Alzheimer’s disease

Jacobsen, J. S., Reinhart, P. H., & Pangalos, M. N. (2005) · NeuroRx · doi:10.1602/neurorx.2.4.612 · Cited by 92 · see citing works

Sustained activation of metabotropic glutamate receptor 5 and protein tyrosine phosphatases mediate the expression of ( S )‐3,5‐dihydroxyphenylglycine‐induced long‐term depression in the hippocampal CA1 region

Huang, C., & Hsu, K. (2005) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.2005.03527.x · Cited by 85 · see citing works

Insulin inhibits amyloid β-induced cell death in cultured human brain pericytes

Rensink, A. A. M., Otte‐Höller, I., de Boer, R., Bosch, R. R., ten Donkelaar, H. J., de Waal, R. M. W., Verbeek, M. M., & Kremer, B. P. H. (2003) · Neurobiology of Aging · doi:10.1016/s0197-4580(03)00039-3 · Cited by 80 · see citing works

Amyloidogenic determinant as a substrate recognition motif of insulin‐degrading enzyme

Kurochkin, I. V. (1998) · FEBS Letters · doi:10.1016/s0014-5793(98)00422-0 · Cited by 79 · see citing works

Toxic effect of a β-amyloid peptide (β22–35) on the hippocampal neuron and its prevention

Takadera, T., Sakura, N., Mohri, T., & Hashimoto, T. (1993) · Neuroscience Letters · doi:10.1016/0304-3940(93)90135-8 · Cited by 77 · see citing works

Activation of Insulin Signal Transduction Pathway and Anti-diabetic Activity of Small Molecule Insulin Receptor Activators

Qureshi, S. A., Ding, V. D. H., Li, Z., Szalkowski, D., Biazzo-Ashnault, D. E., Xie, D., Saperstein, R., Brady, E. J., Huskey, S.-E. W., Shen, X., et al. (2000) · Journal of Biological Chemistry · doi:10.1074/jbc.m006287200 · Cited by 67 · see citing works

Protective effects of insulin‐like growth factor‐I on the somatostatinergic system in the temporal cortex of β‐amyloid‐treated rats

Aguado‐Llera, D., Arilla, E., Campos‐Barros, Á., Puebla‐Jiménez, L., & Barrios, V. (2004) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.2004.02889.x · Cited by 47 · see citing works

Nicotine Enhances the Depressive Actions of Aβ1–40 on Long-Term Potentiation in the Rat Hippocampal CA1 Region In Vivo

Freir, D. B., & Herron, C. E. (2003) · Journal of Neurophysiology · doi:10.1152/jn.00996.2002 · Cited by 46 · see citing works

Impairments of hippocampal synaptic plasticity induced by aggregated beta-amyloid (25–35) are dependent on stimulation-protocol and genetic background

Gengler, S., Gault, V. A., Harriott, P., & Hölscher, C. (2006) · Experimental Brain Research · doi:10.1007/s00221-006-0819-6 · Cited by 38 · see citing works

Impairment of hippocampal long-term potentiation by Alzheimer amyloid ?-peptides

Chen, Q.-S., Kagan, B. L., Hirakura, Y., & Xie, C.-W. (2000) · Journal of Neuroscience Research · doi:10.1002/(sici)1097-4547(20000401)60:1

Intranasal Insulin Therapy for Alzheimer Disease and Amnestic Mild Cognitive Impairment: A Pilot Clinical Trial

Craft, S. (2012) · Archives of Neurology · doi:10.1001/archneurol.2011.233 · Cited by 1,253 · see citing works

Protection of synapses against Alzheimer's-linked toxins: Insulin signaling prevents the pathogenic binding of Aβ oligomers

De Felice, F. G., Vieira, M. N. N., Bomfim, T. R., Decker, H., Velasco, P. T., Lambert, M. P., Viola, K. L., Zhao, W.-Q., Ferreira, S. T., & Klein, W. L. (2009) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0809158106 · Cited by 657 · see citing works

Nose-to-brain drug delivery: An update on clinical challenges and progress towards approval of anti-Alzheimer drugs

Agrawal, M., Saraf, S., Saraf, S., Antimisiaris, S. G., Chougule, M. B., Shoyele, S. A., & Alexander, A. (2018) · Journal of Controlled Release · doi:10.1016/j.jconrel.2018.05.011 · Cited by 630 · see citing works

Long-Acting Intranasal Insulin Detemir Improves Cognition for Adults with Mild Cognitive Impairment or Early-Stage Alzheimer's Disease Dementia

Claxton, A., Baker, L. D., Hanson, A., Trittschuh, E. H., Cholerton, B., Morgan, A., Callaghan, M., Arbuckle, M., Behl, C., & Craft, S. (2015) · Journal of Alzheimer's Disease · doi:10.3233/jad-141791 · Cited by 467 · see citing works

The Aβ oligomer hypothesis for synapse failure and memory loss in Alzheimer’s disease

Ferreira, S. T., & Klein, W. L. (2011) · Neurobiology of Learning and Memory · doi:10.1016/j.nlm.2011.08.003 · Cited by 442 · see citing works

Effects of Regular and Long-Acting Insulin on Cognition and Alzheimer’s Disease Biomarkers: A Pilot Clinical Trial

Craft, S., Claxton, A., Baker, L. D., Hanson, A. J., Cholerton, B., Trittschuh, E. H., Dahl, D., Caulder, E., Neth, B., Montine, T. J., et al. (2017) · Journal of Alzheimer’s Disease · doi:10.3233/jad-161256 · Cited by 335 · see citing works

How does brain insulin resistance develop in Alzheimer's disease?

De Felice, F. G., Lourenco, M. V., & Ferreira, S. T. (2014) · Alzheimer's & Dementia · doi:10.1016/j.jalz.2013.12.004 · Cited by 337 · see citing works

The neuroprotective effects of glucagon-like peptide 1 in Alzheimer’s and Parkinson’s disease: An in-depth review

Reich, N., & Hölscher, C. (2022) · Frontiers in Neuroscience · doi:10.3389/fnins.2022.970925 · Cited by 248 · see citing works

Insulin Receptor Dysfunction Impairs Cellular Clearance of Neurotoxic Oligomeric Aβ

Zhao, W.-Q., Lacor, P. N., Chen, H., Lambert, M. P., Quon, M. J., Krafft, G. A., & Klein, W. L. (2009) · Journal of Biological Chemistry · doi:10.1074/jbc.m109.011015 · Cited by 154 · see citing works

Caloric restriction: Beneficial effects on brain aging and Alzheimer’s disease

Van Cauwenberghe, C., Vandendriessche, C., Libert, C., & Vandenbroucke, R. E. (2016) · Mammalian Genome · doi:10.1007/s00335-016-9647-6 · Cited by 121 · see citing works

Brain glucose metabolism in health, obesity, and cognitive decline-does insulin have anything to do with it? A narrative review

Rebelos, E., Rinne, J. O., Nuutila, P., & Ekblad, L. L. (2021) · Journal of Clinical Medicine · doi:10.3390/jcm10071532 · Cited by 66 · see citing works

ApoE4 expression accelerates hippocampus-dependent cognitive deficits by enhancing Aβ impairment of insulin signaling in an Alzheimer’s disease mouse model

Chan, E. S., Shetty, M. S., Sajikumar, S., Chen, C., Soong, T. W., & Wong, B.-S. (2016) · Scientific Reports · doi:10.1038/srep26119 · Cited by 39 · see citing works

The role of Tetrahydrocannabinol in inducing disrupted signaling cascades, hippocampal atrophy and memory defects

Barfi, E., Tehrani, A. M., Mohammadpanah, M., et al. (2021) · Journal of Chemical Neuroanatomy · doi:10.1016/j.jchemneu.2021.101943 · Cited by 4 · see citing works

Increased extracellular release of hippocampal NE is associated with tetanization of the medial perforant pathway in the freely moving adult male rat

Bronzino, J. D., Kehoe, P., Mallinson, K., et al. (2001) · Hippocampus · doi:10.1002/hipo.1057.abs

14-3-3 Proteins Are Required for Hippocampal Long-Term Potentiation and Associative Learning and Memory

Qiao, H., Foote, M. M., Graham, K. C., Wu, Y., & Zhou, Y. (2014) · Journal of Neuroscience · doi:10.1523/jneurosci.4393-13.2014 · Cited by 74 · see citing works

Increased extracellular release of hippocampal NE is associated with tetanization of the medial perforant pathway in the freely moving adult male rat

Bronzino, J. D., Kehoe, P., Mallinson, K., & Fortin, D. A. (2001) · Hippocampus · doi:10.1002/hipo.1057 · Cited by 26 · see citing works

Hippocampal synaptic plasticity and cognition

Akhondzadeh, S. (1999) · Journal of Clinical Pharmacy and Therapeutics · doi:10.1046/j.1365-2710.1999.00231.x · Cited by 81 · see citing works