ApoE Promotes the Proteolytic Degradation of Aβ

Jiang, Qingguang, Lee, C.Y. Daniel, Mandrekar, Shweta, Wilkinson, Brandy, Cramer, Paige, Zelcer, Noam, Mann, Karen, Lamb, Bruce +9 more·2008·Neuron

DOI 10.1016/j.neuron.2008.04.010

Cited by (876)

Items 101–200 of 876

DNA methylation, a hand behind neurodegenerative diseases
Haoyang Lu, Xinzhou Liu, Yu-Lin DENG, Hong Qing · 2013 · Frontiers in Aging Neuroscience
miR-106b impairs cholesterol efflux and increases Aβ levels by repressing ABCA1 expression
Kim, Jaekwang, Yoon, Hyejin, Ramírez, Cristina M., Lee, Sang-Mi, Hoe, Hyang-Sook, Fernández-Hernando, Carlos, Kim, Jungsu · 2012 · Experimental Neurology
Reducing Human Apolipoprotein E Levels Attenuates Age-Dependent Aβ Accumulation in Mutant Human Amyloid Precursor Protein Transgenic Mice
Bien-Ly, Nga, Gillespie, Anna K., Walker, David, Yoon, Seo Yeon, Huang, Yadong · 2012 · The Journal of Neuroscience
An aging, pathology burden, and glial senescence build-up hypothesis for late onset Alzheimer’s disease
Victor Z. Lau, Leanne M. Ramer, Marie‐Ève Tremblay · 2023 · Nature Communications
Levels of Soluble Apolipoprotein E/Amyloid-β (Aβ) Complex Are Reduced and Oligomeric Aβ Increased with APOE4 and Alzheimer Disease in a Transgenic Mouse Model and Human Samples*
Tai, Leon M., Bilousova, Tina, Jungbauer, Lisa, Roeske, Stephen K., Youmans, Katherine L., Yu, Chunjiang, Poon, Wayne W., Cornwell, Lindsey B., Miller, Carol A., Vinters, Harry V. et al. · 2013 · Journal of Biological Chemistry
Astrocytic Aβ1‐42 uptake is determined by Aβ‐aggregation state and the presence of amyloid‐associated proteins
H. Nielsen, S. Mulder, J. Beliën, R. Musters, P. Eikelenboom, R. Veerhuis · 2010 · Glia
ApoE4 Alters ABCA1 Membrane Trafficking in Astrocytes
Rawat, Varun, Wang, Shaowei, Sima, Jian, Bar, Roni, Liraz, Ori, Gundimeda, Usha, Parekh, Trusha, Chan, Jamie, Johansson, Jan O., Tang, Chongren et al. · 2019 · The Journal of Neuroscience
Apolipoprotein E as a Therapeutic Target in Alzheimer’s Disease: A Review of Basic Research and Clinical Evidence
Yu Yamazaki, Meghan M. Painter, Guojun Bu, Takahisa Kanekiyo · 2016 · CNS Drugs
Aspirin-Triggered Lipoxin A4 Stimulates Alternative Activation of Microglia and Reduces Alzheimer Disease–Like Pathology in Mice
Medeiros, Rodrigo, Kitazawa, Masashi, Passos, Giselle F., Baglietto-Vargas, David, Cheng, David, Cribbs, David H., LaFerla, Frank M. · 2013 · The American Journal of Pathology
Differential diagnosis of Alzheimer’s disease using spectrochemical analysis of blood
Maria Paraskevaidi, Camilo L. M. Morais, Kássio M. G. Lima, Julie S. Snowden, Jennifer A. Saxon, Anna M. T. Richardson, Matthew S. Jones, David M. A. Mann, David Allsop, Pierre L. Martin‐Hirsch et al. · 2017 · Proceedings of the National Academy of Sciences
Prostaglandin signaling suppresses beneficial microglial function in Alzheimer’s disease models
Johansson, Jenny U., Woodling, Nathaniel S., Wang, Qian, Panchal, Maharshi, Liang, Xibin, Trueba-Saiz, Angel, Brown, Holden D., Mhatre, Siddhita D., Loui, Taylor, Andreasson, Katrin I. · 2015 · Journal of Clinical Investigation
Opposing effects of viral mediated brain expression of apolipoprotein E2 (apoE2) and apoE4 on apoE lipidation and Aβ metabolism in apoE4-targeted replacement mice
Hu, Jin, Liu, Chia-Chen, Chen, Xiao-Fen, Zhang, Yun-wu, Xu, Huaxi, Bu, Guojun · 2015 · Molecular Neurodegeneration
The Role of the ATP-Binding Cassette A1 (ABCA1) in Human Disease
Leonor Jacobo‐Albavera, Mayra Domínguez‐Pérez, Diana Jhoseline Medina-Leyte, Antonia González-Garrido, María Teresa Villarreal-Molina · 2021 · International Journal of Molecular Sciences
Anti-apoE immunotherapy inhibits amyloid accumulation in a transgenic mouse model of Aβ amyloidosis
Kim, Jungsu, Eltorai, Adam E.M., Jiang, Hong, Liao, Fan, Verghese, Philip B., Kim, Jaekwang, Stewart, Floy R., Basak, Jacob M., Holtzman, David M. · 2012 · Journal of Experimental Medicine
Apolipoprotein E and Alzheimer's disease
Benjamin Troutwine, Laylan Hamid, Colton R Lysaker, Taylor A. Strope, Heather Wilkins · 2021 · Acta Pharmaceutica Sinica B
More than cholesterol transporters: lipoprotein receptors in CNS function and neurodegeneration
Lane-Donovan, Courtney, Philips, Gary T., Herz, Joachim · 2014 · Neuron
Deacetylation of TFEB promotes fibrillar Aβ degradation by upregulating lysosomal biogenesis in microglia
Jintao Bao, Liangjun Zheng, Qi Zhang, Xinya Li, Xuefei Zhang, Zeyang Li, Xue Bai, Zhong Zhang, Wei Huo, Xuyang Zhao et al. · 2016 · Protein & Cell
Passive immunotherapies targeting Aβ and tau in Alzheimer's disease
Steven Samuel Plotkin, Neil R. Cashman · 2020 · Neurobiology of Disease
Diet Intervention and Cerebrospinal Fluid Biomarkers in Amnestic Mild Cognitive Impairment
Jennifer L. Bayer-Carter, Pattie S. Green, Thomas Jude Montine, Brian T. VanFossen, Laura D. Baker, G. Stennis Watson, Laura M. Bonner, Maureen Callaghan, James B. Leverenz, Brooke K. Walter et al. · 2011 · Archives of Neurology
Nuclear Receptors License Phagocytosis by Trem2<sup>+</sup>Myeloid Cells in Mouse Models of Alzheimer's Disease
Savage, Julie C., Jay, Taylor, Goduni, Elanda, Quigley, Caitlin, Mariani, Monica M., Malm, Tarja, Ransohoff, Richard M., Lamb, Bruce T., Landreth, Gary E. · 2015 · The Journal of Neuroscience
Cholesterol metabolism in Huntington disease
Karasinska, Joanna M., Hayden, Michael R. · 2011 · Nature Reviews Neurology
Liver X receptor activation restores memory in aged AD mice without reducing amyloid
Vanmierlo, Tim, Rutten, Kris, Dederen, Jos, Bloks, Vincent W., van Vark-van der Zee, Leonie C., Kuipers, Folkert, Kiliaan, Amanda, Blokland, Arjan, Sijbrands, Eric J.G., Steinbusch, Harry et al. · 2011 · Neurobiology of Aging
Comment on “ApoE-Directed Therapeutics Rapidly Clear β-Amyloid and Reverse Deficits in AD Mouse Models”
Fitz, Nicholas F., Cronican, Andrea A., Lefterov, Iliya, Koldamova, Radosveta · 2013 · Science
Specific Loss of Brain ABCA1 Increases Brain Cholesterol Uptake and Influences Neuronal Structure and Function
Joanna M. Karasinska, Franz Rinninger, Dieter Lütjohann, Piers Ruddle, Sonia Franciosi, Janine K. Kruit, Roshni Rebecca Singaraja, Veronica Hirsch‐Reinshagen, Jianjia Fan, Liam R. Brunham et al. · 2009 · Journal of Neuroscience
Design and Validation of Liposomal ApoE2 Gene Delivery System to Evade Blood–Brain Barrier for Effective Treatment of Alzheimer’s Disease
Arora, Sanjay, Layek, Buddhadev, Singh, Jagdish · 2021 · Molecular Pharmaceutics
Insulin-Degrading Enzyme Sorting in Exosomes: A Secretory Pathway for a Key Brain Amyloid-β Degrading Protease
Ayelén Bulloj, María Celeste Leal, Huaxi Xu, Eduardo Miguel Castaño, Laura Morelli · 2010 · Journal of Alzheimer s Disease
Jujuboside A promotes Aβ clearance and ameliorates cognitive deficiency in Alzheimer's disease through activating Axl/HSP90/PPARγ pathway
Mu Zhang, Qian Cheng, Zu‐Guo Zheng, Fei Qian, Yanyan Wang, Pyone Myat Thu, Xin Zhang, Yaping Zhou, Lifan Tu, Qingling Liu et al. · 2018 · Theranostics
The ketogenic diet as a potential treatment and prevention strategy for Alzheimer's disease
Gina M. Broom, Ian C. Shaw, Julia J. Rucklidge · 2018 · Nutrition
Neurovascular Defects and Faulty Amyloid-β Vascular Clearance in Alzheimer's Disease
Abhay P. Sagare, Robert D. Bell, Berislav V. Zloković · 2012 · Journal of Alzheimer s Disease
ATP-binding cassette transporter A1: From metabolism to neurodegeneration
Koldamova, Radosveta, Fitz, Nicholas F., Lefterov, Iliya · 2014 · Neurobiology of Disease
The E3 ubiquitin ligase IDOL induces the degradation of the low density lipoprotein receptor family members VLDLR and ApoER2
Hong, Cynthia, Duit, Sarah, Jalonen, Pilvi, Out, Ruud, Scheer, Lilith, Sorrentino, Vincenzo, Boyadjian, Rima, Rodenburg, Kees W., Foley, Edan, Korhonen, Laura et al. · 2010 · Journal of Biological Chemistry
Microglial activation states and their implications for Alzheimer's Disease
Zachary Valiukas, Kathy Tangalakis, Vasso Apostolopoulos, Jack Feehan · 2025 · The Journal of Prevention of Alzheimer s Disease
Apolipoprotein E in Synaptic Plasticity and Alzheimer’s Disease: Potential Cellular and Molecular Mechanisms
Kim, Jaekwang, Yoon, Hyejin, Basak, Jacob, Kim, Jungsu · 2014 · Molecules and Cells
Liver X receptors as regulators of macrophage inflammatory and metabolic pathways
A-González, Noelia, Castrillo, Antonio · 2011 · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease
Chaperone signalling complexes in Alzheimer's disease
John Koren, Umesh K. Jinwal, Daniel C. Lee, Jeffrey R. Jones, Cody L. Shults, Amelia G. Johnson, Laura J. Anderson, Chad A. Dickey · 2008 · Journal of Cellular and Molecular Medicine
Advances in the pathogenesis of Alzheimer’s disease: a re-evaluation of amyloid cascade hypothesis
Suzhen Dong, Yale Duan, Yinghe Hu, Zheng Zhao · 2012 · Translational Neurodegeneration
Vitamin A and Retinoic Acid in Cognition and Cognitive Disease
Marta U. Wołoszynowska-Fraser, Azita Kouchmeshky, Peter J. A. McCaffery · 2020 · Annual Review of Nutrition
Beta Amyloid Aggregation Inhibitors: Small Molecules as Candidate Drugs for Therapy of Alzheimers Disease
Francesca Re, Cristina Airoldi, Cristiano Zona, Massimo Masserini, Barbara La Ferla, N. Quattrocchi, Francesco Nicotra · 2010 · Current Medicinal Chemistry
Abca1 Deficiency Affects Alzheimer's Disease-Like Phenotype in Human ApoE4 But Not in ApoE3-Targeted Replacement Mice
Nicholas Francis Fitz, Andrea A. Cronican, Muzamil Saleem, Abdul H. Fauq, Robert Chapman, Iliya M. Lefterov, Radosveta P. Koldamova · 2012 · Journal of Neuroscience
Apolipoprotein-E (Apoe) ε4 and cognitive decline over the adult life course
Rawle, Mark James, Davis, Daniel, Bendayan, Rebecca, Wong, Andrew, Kuh, Diana, Richards, Marcus · 2018 · Translational Psychiatry
Drug development for alzheimer’s disease: Microglia induced neuroinflammation as a target
Dong, Yuan, Li, Xiaoheng, Cheng, Jinbo, Hou, Lin · 2019 · International Journal of Molecular Sciences
Strategies for the Inhibition of Protein Aggregation in Human Diseases
Manuela Bartolini, Vincenza Andrisano · 2010 · ChemBioChem
Role of ABC Transporters in the Pathogenesis of Alzheimer’s Disease
Alaa H. Abuznait, Amal Kaddoumi · 2012 · ACS Chemical Neuroscience
Association of APOE with tau-tangle pathology with and without β-amyloid
José M. Farfel, Lei Yu, Philip L. De Jager, Julie A. Schneider, David Alan Bennett · 2015 · Neurobiology of Aging
Reversal of apoE4-driven brain pathology and behavioral deficits by bexarotene
Boehm-Cagan, Anat, Michaelson, Daniel M. · 2014 · The Journal of Neuroscience
The link between altered cholesterol metabolism and Alzheimer's disease
Paola Gamba, Gabriella Testa, Barbara Sottero, Simona Gargiulo, Giuseppe Poli, Gabriella Leonarduzzi · 2012 · Annals of the New York Academy of Sciences
The endocytic pathway in microglia during health, aging and Alzheimer’s disease
Solé-Domènech, Santiago, Cruz, Dana L., Capetillo-Zarate, Estibaliz, Maxfield, Frederick R. · 2016 · Ageing Research Reviews
Disruption of astrocyte-neuron cholesterol cross talk affects neuronal function in Huntington’s disease
Marta Valenza, Manuela Marullo, Eleonora Di Paolo, Eugenio Cesana, Chiara Zuccato, Gerardo Rosario Biella, Elena F. Cattaneo · 2014 · Cell Death and Differentiation
Sensory Network Dysfunction, Behavioral Impairments, and Their Reversibility in an Alzheimer's β-Amyloidosis Mouse Model
Daniel W. Wesson, Anne H. Borkowski, Gary E. Landreth, Ralph A. Nixon, Efrat Levy, Donald A. Wilson · 2011 · Journal of Neuroscience
Allopregnanolone Promotes Regeneration and Reduces β-Amyloid Burden in a Preclinical Model of Alzheimer's Disease
Shuhua Chen, Jun Ming Wang, Ronald W. Irwin, Jia Yao, Lifei Liu, Roberta Dı́az Brinton · 2011 · PLoS ONE
A second class of nuclear receptors for oxysterols: Regulation of RORα and RORγ activity by 24S-hydroxycholesterol (cerebrosterol)
Yongjun Wang, Naresh Kumar, Christine Crumbley, Patrick R. Griffin, Thomas P. Burris · 2010 · Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids
Decoding microglial immunometabolism: a new frontier in Alzheimer's disease research
Jung, Eun Sun, Choi, Hayoung, Mook-Jung, Inhee · 2025 · Molecular Neurodegeneration
Phospholipids of APOE lipoproteins activate microglia in an isoform-specific manner in preclinical models of Alzheimer’s disease
Fitz, Nicholas F., Nam, Kyong Nyon, Wolfe, Cody M., Letronne, Florent, Playso, Brittany E., Iordanova, Bistra E., Kozai, Takashi D. Y., Biedrzycki, Richard J., Kagan, Valerian E., Tyurina, Yulia Y. et al. · 2021 · Nature Communications
microRNA-33 Regulates ApoE Lipidation and Amyloid-β Metabolism in the Brain
Kim, Jaekwang, Yoon, Hyejin, Horie, Takahiro, Burchett, Jack M., Restivo, Jessica L., Rotllan, Noemi, Ramírez, Cristina M., Verghese, Philip B., Ihara, Masafumi, Hoe, Hyang-Sook et al. · 2015 · The Journal of Neuroscience
Anti-ApoE Antibody Given after Plaque Onset Decreases Aβ Accumulation and Improves Brain Function in a Mouse Model of Aβ Amyloidosis
Liao, Fan, Hori, Yukiko, Hudry, Eloise, Bauer, Adam Q., Jiang, Hong, Mahan, Thomas E., Lefton, Katheryn B., Zhang, Tony J., Dearborn, Joshua T., Kim, Jungsu et al. · 2014 · The Journal of Neuroscience
Genetic markers for diagnosis and pathogenesis of Alzheimer's disease
Dong‐Hee Kim, Seung Hyeon Yeo, Jeong-Min Park, Ji Ye Choi, Tae-Hee Lee, Soon Yong Park, Mee Sun Ock, Jungwoo Eo, Heui‐Soo Kim, Hee‐Jae Cha · 2014 · Gene
Clusterin Binds to Aβ1–42 Oligomers with High Affinity and Interferes with Peptide Aggregation by Inhibiting Primary and Secondary Nucleation
Marten Beeg, Matteo Stravalaci, Margherita Romeo, Arianna Dorotea Carrà, Alfredo Cagnotto, Alessandro Rossi, Luisa Diomede, Mario Salmona, Marco Gobbi · 2016 · Journal of Biological Chemistry
Norepinephrine Promotes Microglia to Uptake and Degrade Amyloid β Peptide through Upregulation of Mouse Formyl Peptide Receptor 2 and Induction of Insulin-Degrading Enzyme
Yan Kong, Lingfei Ruan, Lihua Qian, Xiaolei Liu, Yingying Le · 2010 · Journal of Neuroscience
Nuclear receptors as therapeutic targets for Alzheimer's disease
Mandrekar-Colucci, Shweta, Landreth, Gary E · 2011 · Expert Opinion on Therapeutic Targets
Mechanism mediating oligomeric Aβ clearance by naïve primary microglia.
Cheng-Ning Yang, Y. Shiao, F. Shie, Bo-Shen Guo, Pei-Hao Chen, C. Cho, Yi-Jen Chen, Fong-Lee Huang, H. Tsay · 2011 · Neurobiology of Disease
Cell-specific production, secretion, and function of apolipoprotein E
Kockx, Maaike, Traini, Mathew, Kritharides, Leonard · 2018 · Journal of Molecular Medicine
Microglia in Alzheimer’s Disease in the Context of Tau Pathology
Juan Ramón Perea, Marta Bolós, Jesús Ávila · 2020 · Biomolecules
Insulin resistance in Alzheimer's disease
Kelly T. Dineley, Jordan B. Jahrling, Larry A. Denner · 2014 · Neurobiology of Disease
PPARs in the central nervous system: roles in neurodegeneration and neuroinflammation
Juan Manuel Zolezzi, Manuel J. Santos, Sussy Bastias Candia, Claudio Pinto, Juan Alejandro Godoy, Nibaldo C. Inestrosa · 2017 · Biological reviews/Biological reviews of the Cambridge Philosophical Society
The amyloid cascade and Alzheimer's disease therapeutics: theory versus observation
Rudy J. Castellani, Germán Plascencia‐Villa, George L. Perry · 2019 · Laboratory Investigation
ABC Transporters in the CNS – An Inventory
Anika M. S. Hartz, Björn Bauer · 2011 · Current Pharmaceutical Biotechnology
ApoE4 induces Aβ42, tau, and neuronal pathology in the hippocampus of young targeted replacement apoE4 mice
Liraz, Ori, Boehm-Cagan, Anat, Michaelson, Daniel M · 2013 · Molecular Neurodegeneration
Role of Cholesterol in APP Metabolism and Its Significance in Alzheimer’s Disease Pathogenesis
Mahua Maulik, David A. Westaway, Jack H. Jhamandas, Satyabrata Kar · 2012 · Molecular Neurobiology
The vascular contribution to Alzheimer's disease
Robin Altman, John C. Rutledge · 2010 · Clinical Science
ABCA1 Agonist Reverses the ApoE4-Driven Cognitive and Brain Pathologies
Boehm-Cagan, Anat, Bar, Roni, Liraz, Ori, Bielicki, John K., Johansson, Jan O., Michaelson, Daniel M. · 2016 · Journal of Alzheimer's Disease
Soluble apoE/Aβ complex: mechanism and therapeutic target for APOE4-induced AD risk
Tai, Leon M, Mehra, Shipra, Shete, Varsha, Estus, Steve, Rebeck, G William, Bu, Guojun, LaDu, Mary Jo · 2014 · Molecular Neurodegeneration
Cerebrospinal fluid biomarkers for understanding multiple aspects of Alzheimer’s disease pathogenesis
Kunal Dhiman, Kaj Blennow, Henrik Zetterberg, Ralph Nigel Martins, Veer Bala Gupta · 2019 · Cellular and Molecular Life Sciences
Suppression of Alzheimer-Associated Inflammation by Microglial Prostaglandin-E2EP4 Receptor Signaling
Nathaniel S. Woodling, Qian Wang, Prachi G. Priyam, Paul B. Larkin, Ju Shi, Jenny U. Johansson, Irene A. Zagol-Ikapitte, Olivier G. Boutaud, Katrin I. Andreasson · 2014 · Journal of Neuroscience
ACAT1/SOAT1 as a Therapeutic Target for Alzheimer's Disease
Shibuya, Yohei, Chang, Catherine CY, Chang, Ta-Yuan · 2015 · Future Medicinal Chemistry
The Neurobiology and Age-Related Prevalence of the ε4 Allele of Apolipoprotein E in Alzheimer’s Disease Cohorts
Heffernan, Amy L., Chidgey, Cameron, Peng, Po, Masters, Colin L., Roberts, Blaine R. · 2016 · Journal of Molecular Neuroscience
Phytosterols: Potential Metabolic Modulators in Neurodegenerative Diseases
Niti Sharma, Mario A. Tan, Seong Soo A. An · 2021 · International Journal of Molecular Sciences
Multiscale NIR-II Imaging-Guided Brain-Targeted Drug Delivery Using Engineered Cell Membrane Nanoformulation for Alzheimer’s Disease Therapy
Dehua Huang, Qianwu Wang, Yuheng Cao, Hongchao Yang, Meng Li, Feng Wu, Yejun Zhang, Guangcun Chen, Qiangbin Wang · 2023 · ACS Nano
The Pro-Neurotrophin Receptor Sortilin Is a Major Neuronal Apolipoprotein E Receptor for Catabolism of Amyloid-β Peptide in the Brain
Anne-Sophie Carlo, Camilla Gustafsen, Guido Mastrobuoni, Morten Schallburg Nielsen, Tilman Burgert, Daniela Hartl, Michael Rohe, Anders Nykjær, Joachim Herz, Jöerg Heeren et al. · 2013 · Journal of Neuroscience
Insulin-Degrading Enzyme: Structure-Function Relationship and its Possible Roles in Health and Disease
Agata C Fernández-Gamba, M. Leal, Laura Morelli, E. Castano · 2009 · Current Pharmaceutical Design
Inhibiting ACAT1/SOAT1 in microglia stimulates autophagy-mediated lysosomal proteolysis and increases Aβ1-42 clearance
Shibuya, Yohei, Chang, Catherine C.Y., Huang, Li-Hao, Bryleva, Elena Y., Chang, Ta-Yuan · 2014 · The Journal of Neuroscience
The effect of insomnia on development of Alzheimer’s disease
Shaghayegh Sadeghmousavi, Mahsa Eskian, Farzaneh Rahmani, Nima Rezaei · 2020 · Journal of Neuroinflammation
Nutrition and Alzheimer's disease: The detrimental role of a high carbohydrate diet
Stephanie Seneff, Glyn Wainwright, Luca Mascitelli · 2011 · European Journal of Internal Medicine
Allopregnanolone as regenerative therapeutic for Alzheimer's disease: Translational development and clinical promise
Ronald W. Irwin, Roberta Dı́az Brinton · 2013 · Progress in Neurobiology
ABC Transporters and the Alzheimer’s Disease Enigma
Andrea M. Wolf, Björn Bauer, Anika M. S. Hartz · 2012 · Frontiers in Psychiatry
The effects of cholesterol on learning and memory
Bernard G. Schreurs · 2010 · Neuroscience & Biobehavioral Reviews
ABCA1 influences neuroinflammation and neuronal death
Karasinska, Joanna M., de Haan, Willeke, Franciosi, Sonia, Ruddle, Piers, Fan, Jianjia, Kruit, Janine K., Stukas, Sophie, Lütjohann, Dieter, Gutmann, David H., Wellington, Cheryl L. et al. · 2013 · Neurobiology of Disease
Deletion of CD14 Attenuates Alzheimer's Disease Pathology by Influencing the Brain's Inflammatory Milieu
Erin G. Reed-Geaghan, Quillan W. Reed, Paige E. Cramer, Gary E. Landreth · 2010 · Journal of Neuroscience
Microglial Activation in Alzheimers Disease
Johannes C. M. Schlachetzki, Michael Hüll · 2009 · Current Alzheimer Research
At-Risk Populations in Sports-Related Concussion
Jeffrey S. Kutcher, James T. Eckner · 2010 · Current Sports Medicine Reports
Interactions between inflammation, sex steroids, and Alzheimer’s disease risk factors
M. F. Uchoa, V. Moser, Christian J. Pike · 2016 · Frontiers in neuroendocrinology (Print)
Effect of Apolipoprotein E Genotype and Diet on Apolipoprotein E Lipidation and Amyloid Peptides
Angela J. Hanson, Jennifer L. Bayer-Carter, Pattie S. Green, Thomas Jude Montine, Charles W. Wilkinson, Laura D. Baker, G. Stennis Watson, Laura M. Bonner, Maureen Callaghan, James B. Leverenz et al. · 2013 · JAMA Neurology
The role of ATP-binding cassette transporter A1 in Alzheimer's disease and neurodegeneration
Koldamova, Radosveta, Fitz, Nicholas F., Lefterov, Iliya · 2010 · Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids
Impact of Apolipoprotein E on Alzheimer’s Disease
Paul S. Hauser, Robert O. Ryan · 2013 · Current Alzheimer Research
Current advances in the treatment of Alzheimer's disease: focused on considerations targeting Aβ and tau
Hongqi Yang, Zhikun Sun, Shengdi Chen · 2012 · Translational Neurodegeneration
Genetic and Transcriptomic Profiles of Inflammation in Neurodegenerative Diseases: Alzheimer, Parkinson, Creutzfeldt-Jakob and Tauopathies
López González, Irene, Garcia-Esparcia, Paula, Llorens, Franc, Ferrer, Isidre · 2016 · International Journal of Molecular Sciences
Apolipoprotein E, amyloid-beta, and neuroinflammation in Alzheimer’s disease
Evan Dorey, Nina Chang, Qing Yan Liu, Ze Yang, Wandong Zhang · 2014 · Neuroscience Bulletin
Endothelin-Converting Enzyme-2 Is Increased in Alzheimer’s Disease and Up-Regulated by Aβ
Jennifer C Palmer, Shabnam Baig, Patrick G. Kehoe, Seth Love · 2009 · American Journal Of Pathology
Amyloid-beta aggregation implicates multiple pathways in Alzheimer’s disease: Understanding the mechanisms
Musa O. Iliyasu, Sunday Abraham Musa, Sunday Blessing Oladele, Abdullahi Ibrahim Iliya · 2023 · Frontiers in Neuroscience
Transthyretin and the brain re-visited: Is neuronal synthesis of transthyretin protective in Alzheimer's disease?
Xinyi Li, Joel N. Buxbaum · 2011 · Molecular Neurodegeneration
High-Density Lipoproteins and Cerebrovascular Integrity in Alzheimer’s Disease
Sophie K. Stukas, Jérôme Robert, Cheryl Lea Wellington · 2014 · Cell Metabolism