ApoE Promotes the Proteolytic Degradation of Aβ
Jiang, Qingguang, Lee, C.Y. Daniel, Mandrekar, Shweta, Wilkinson, Brandy, Cramer, Paige, Zelcer, Noam, Mann, Karen, Lamb, Bruce, Willson, Timothy M., Collins, Jon L., Richardson, Jill C., Smith, Jonathan D., Comery, Thomas A., Riddell, David, Holtzman, David M., Tontonoz, Peter, Landreth, Gary E.·2008·Neuron
Cited by (875)
Items 501–600 of 875
- Exploration of 16 candidate genes identifies the association of IDE with Alzheimer's disease in Han ChineseFen Wang, Chang Shu, Longfei Jia, Xiumei Zuo, Yong‐Biao Zhang, Aihong Zhou, Wei Qin, Haiqing Song, Cuibai Wei, Feng Zhang et al. · 2010 · Neurobiology of Aging
- Calpain Inhibition as a Potential Treatment of Alzheimer's DiseaseGodfrey S. Getz · 2012 · American Journal Of Pathology
- Liver X receptor agonist treatment significantly affects phenotype and transcriptome of APOE3 and APOE4 Abca1 haplo-deficient miceCarter, Alexis Y., Letronne, Florent, Fitz, Nicholas F., Mounier, Anais, Wolfe, Cody M., Nam, Kyong Nyon, Reeves, Valerie L., Kamboh, Hafsa, Lefterov, Iliya, Koldamova, Radosveta · 2017 · PLOS ONE
- A blood-based signature of cerebrospinal fluid Aβ1–42 statusBenjamin Goudey, Bowen John Fung, Christine Schieber, Noel Garry Faux, Michael Walter Weiner, Paul S. S. Aisen, Ronald Carl Petersen, Clifford R. Jack, William J. Jagust, John Q. Trojanowki et al. · 2019 · Scientific Reports
- Identification of a Chrysanthemic Ester as an Apolipoprotein E Inducer in AstrocytesJianjia Fan, Shahab Zareyan, Wenchen Zhao, Yoko Shimizu, Tom A. Pfeifer, Jun‐Hyung Tak, Murray B. Isman, Bernard G. Van den Hoven, Mark E. Duggan, Michael W. Wood et al. · 2016 · PLoS ONE
- Effect of rosiglitazone on amyloid precursor protein processing and Aβ clearance in streptozotocin-induced rat model of Alzheimer's disease.Li Wang, Wei Liu, Ying Fan, Tingting Liu, Chunjiang Yu · 2017 · Europe PMC (PubMed Central)
- Genetic predictors of outcome following traumatic brain injuryRobert H. Lipsky, Mingkuan Lin · 2015 · Handbook of clinical neurology
- Synthesis and Identification of New Flavonoids Targeting Liver X Receptor β Involved Pathway as Potential Facilitators of Aβ Clearance with Reduced Lipid AccumulationYun Hu, Yaqi Yang, Yanjun Yu, Gesi Wen, Nana Shang, Wei Zhuang, Dihan Lu, Binhua Zhou, Baoxia Liang, Xin Yue et al. · 2013 · Journal of Medicinal Chemistry
- Impact of Age on the Cerebrovascular Proteomes of Wild-Type and Tg-SwDI MiceJames L. Searcy, Thierry Le Bihan, Natalia Salvadores, James McCulloch, Karen J. Horsburgh · 2014 · PLoS ONE
- The serine protease HtrA1 contributes to the formation of an extracellular 25-kDa apolipoprotein E fragment that stimulates neuritogenesisSonia Sanz Muñoz, Hongyun Li, Kalani R. Ruberu, Qian Chu, Alan Saghatelian, Lezanne Ooi, Brett Garner · 2018 · Journal of Biological Chemistry
- 5-HT3 Antagonist Ondansetron Increases apoE Secretion by Modulating the LXR-ABCA1 PathwayMotoko Shinohara, Mitsuru Shinohara, Jing Zhao, Yuan Fu, Chia‐Chen Liu, Takahisa Kanekiyo, Guojun Bu · 2019 · International Journal of Molecular Sciences
- New Hope from an Old Drug: Fighting Alzheimer's Disease with the Cancer Drug Bexarotene (Targretin)?Giorgio Aicardi · 2013 · Rejuvenation Research
- MicroRNAs in brain cholesterol metabolism and their implications for Alzheimer's diseaseYoon, Hyejin, Flores, Luis F., Kim, Jungsu · 2016 · Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids
- Activation of LXRβ Signaling in the Amygdala Confers Anxiolytic Effects Through Rebalancing Excitatory and Inhibitory Neurotransmission upon Acute StressWen Yu, Lu Wang, Le Yang, Yanjiao Li, Min Wang, Chen Qiu, Qi Yang, Xubo Li, Yunlong Huang, Rui Liu et al. · 2020 · Neurotherapeutics
- The LXR agonist GW3965 increases apoA-I protein levels in the central nervous system independent of ABCA1Sophie K. Stukas, Sharon May, Anna Wilkinson, Jeniffer Y. Chan, James J. Donkin, Cheryl Lea Wellington · 2011 · Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids
- Efficient Processing of Alzheimer's Disease Amyloid-Beta Peptides by Neuroectodermally Converted Mesenchymal Stem CellsHansjörg Habisch, Benjamin Schmid, Christine A. F. Von Arnim, Albert Christian Ludolph, Rolf Erwin Brenner, Alexander Storch · 2009 · Stem Cells and Development
- A pleiotropic effect of the APOE gene: association of APOE polymorphisms with multibacillary leprosy in Han Chinese from Southwest ChinaD. Wang, Dengfeng Zhang, Guiyun Li, R. Bi, Yu Fan, Yong Wu, Xiaohan Yu, Heng Long, Y.‐Y. Li, Yong‐Gang Yao · 2017 · British Journal of Dermatology
- Apolipoprotein E ablation decreases synaptic vesicular zinc in the brainJoo‐Yong Lee, Eunsil Cho, Tae-Youn Kim, Dong‐Kyu Kim, Richard D. Palmiter, Irene Volitakis, Jong S. Kim, Ashley Ian Bush, Jae‐Young Koh · 2010 · BioMetals
- High-density lipoprotein-related cholesterol metabolism in Alzheimer's diseasePedrini, Steve, Chatterjee, Pratishtha, Hone, Eugene, Martins, Ralph N. · 2021 · Journal of Neurochemistry
- Cognitive Impairment in Neurological Diseases: Lessons from Apolipoprotein EJiong Shi, Pengcheng Han, Sandra M. Kuniyoshi · 2013 · Journal of Alzheimer s Disease
- Neurosteroids and Oxysterols as Potential Therapeutic Agents for Glaucoma and Alzheimer’s DiseaseMakoto Ishikawa, Takeshi Yoshitomi, Douglas F. Covey, Charles F. Zorumski, Yukitoshi Izumi · 2018 · Neuropsychiatry
- Apolipoprotein E Interferes with IAPP Aggregation and Protects Pericytes from IAPP-Induced ToxicityAnna L. Gharibyan, Tohidul Islam, Nina Pettersson, Solmaz Surano, Johanna Lundgren, Gabriella Johansson, Mélany Genot, Nina Schultz, Malin Wennström, Anders Olofsson · 2020 · Biomolecules
- Identification of Side Chain Oxidized Sterols as Novel Liver X Receptor Agonists with Therapeutic Potential in the Treatment of Cardiovascular and Neurodegenerative DiseasesNa Zhan, Boyang Wang, Nikita Martens, Yankai Liu, Shangge Zhao, Gardi J. Voortman, Jeroen van Rooij, Frank P. J. Leijten, Tim Vanmierlo, Folkert Kuipers et al. · 2023 · International Journal of Molecular Sciences
- An ABCA1-independent pathway for recycling a poorly lipidated 8.1 nm apolipoprotein E particle from gliaFan, Jianjia, Stukas, Sophie, Wong, Charmaine, Chan, Jennifer, May, Sharon, DeValle, Nicole, Hirsch-Reinshagen, Veronica, Wilkinson, Anna, Oda, Michael N., Wellington, Cheryl L. · 2011 · Journal of Lipid Research
- Liver X receptors and cholesterol metabolism: role in ventral midbrain development and neurodegenerationSpyridon Theofilopoulos, Ernest Arenas · 2015 · F1000Prime Reports
- Cell type-specific functions of Alzheimer's disease endocytic risk genesManinger, Johanna-Katharina, Nowak, Karolina, Goberdhan, Srilakshmi, O'Donoghue, Rachel, Connor-Robson, Natalie · 2024 · Philosophical Transactions of the Royal Society B: Biological Sciences
- Myelin-reactive B cells exacerbate CD4+ T cell-driven CNS autoimmunity in an IL-23-dependent mannerFazazi, Mohamed Reda, Doss, Prenitha Mercy Ignatius Arokia, Pereira, Resel, Fudge, Neva, Regmi, Aryan, Joly-Beauparlant, Charles, Akbar, Irshad, Yeola, Asmita Pradeep, Mailhot, Benoit, Baillargeon, Joanie et al. · 2024 · Nature Communications
- The APOE–Microglia Axis in Alzheimer’s Disease: Functional Divergence and Therapeutic Perspectives—A Narrative ReviewAiwei Liu, Tingyue Wang, Liu Yang, Yu Zhou · 2025 · Brain Sciences
- Current View from Alzheimer Disease to Type 2 Diabetes MellitusMahmood Rasool, Arif Malik, Aamer Mahmood Qazi, ISHFAQ AHMAD SHEIKH, Abdul Manan, Sumaira Shaheen, Mahmood Husain Qazi, Adeel Chaudhary, Adel Mohammed Abuzenadah, Muhammad Asif et al. · 2014 · CNS & Neurological Disorders - Drug Targets
- Epigenetic Regulation of SNAP25 Prevents Progressive Glutamate Excitotoxicty in Hypoxic CA3 NeuronsSuryanarayan Biswal, Debashree Das, Kalpana Kumari Barhwal, Ashish Kumar, Tapas Chandra Nag, Mahendra Kumar Thakur, Sunil Kumar Hota, Bhuvnesh Kumar · 2016 · Molecular Neurobiology
- The p38 mitogen activated protein kinase regulates β-amyloid protein internalization through the α7 nicotinic acetylcholine receptor in mouse brainKaige Ma, Jia Lv, Weina Yang, Ke-Wei Chang, Xiaodan Hu, Lili Shi, Wan-Ying Zhai, Hang-Fan Zong, Yi‐Hua Qian · 2017 · Brain Research Bulletin
- Therapies for Alzheimer’s disease: a metabolic perspectiveRaquel Domingues, Cláudia Pereira, Maria Teresa Cruz, Ana Silva · 2021 · Molecular Genetics and Metabolism
- Does Alzheimer's disease stem in the gastrointestinal system?Pariya Khodabakhsh, Maryam Bazrgar, Leila Dargahi, Fatemeh Mohagheghi, Afsaneh Asgari Taei, Siavash Parvardeh, Abolhassan Ahmadiani · 2021 · Life Sciences
- APOE 4 and Cognitive Dysfunction in Multiple Sclerosis: A ReviewOmar Ghaffar, Anthony Feinstein · 2010 · Journal of Neuropsychiatry
- Neuronal cholesterol esterification by ACAT1 in Alzheimer's diseaseTa‐Yuan Chang, Catherine C.Y. Chang, Elena Y. Bryleva, Maximillian A. Rogers, Stephanie R Murphy · 2010 · IUBMB Life
- Neurovascular Alterations in Alzheimer’s Disease: Transporter Expression Profiles and CNS Drug AccessMitchell P. McInerney, Jennifer Lynn Short, Joseph A. Nicolazzo · 2017 · The AAPS Journal
- Association Between Common Variants of APOE , ABCA7 , A2M , BACE1 , and Cerebrospinal Fluid Biomarkers in Alzheimer’s Disease: Data from the PUMCH Dementia CohortLiling Dong, Chenhui Mao, Caiyan Liu, Jie Li, Xinying Huang, Jie Wang, Dan Lei, Shanshan Chu, Longze Sha, Qi Xu et al. · 2021 · Journal of Alzheimer s Disease
- Impact of APOE genotype on prion-type propagation of tauopathyTristan Williams, Alejandra Jolie Ruiz, Angelica Maria Ruiz, Quan Vo, Wangchen Tsering, Guilian M. Xu, Karen N. McFarland, Benoit I. Giasson, Patrick M. Sullivan, David Borchelt et al. · 2022 · Acta Neuropathologica Communications
- Activation of Liver X Receptors and Peroxisome Proliferator-Activated Receptors by Lipid Extracts of Brown Seaweeds: A Potential Application in Alzheimer’s Disease?Nikita Martens, Na Zhan, Gardi J. Voortman, Frank P. J. Leijten, Connor van Rheenen, Suzanne van Leerdam, Xicheng Geng, Michiel Huybrechts, Hongbing Liu, Johan W. Jonker et al. · 2023 · Nutrients
- Understanding the Role of miR-33 in Brain Lipid Metabolism: Implications for Alzheimer's DiseaseJaouen, Florence, Gascon, Eduardo · 2016 · The Journal of Neuroscience
- Altered effective connectivity anchored in the posterior cingulate cortex and the medial prefrontal cortex in cognitively intact elderly APOE ε4 carriers: a preliminary studyAlzheimer’s Disease Neuroimaging Initiative, Xiao Luo, Kaicheng Li, Yunlu Jia, Qingze Zeng, Yeerfan Jiaerken, Tiantian Qiu, Peiyu Huang, Xiaojun Xu, Zhujing Shen et al. · 2018 · Brain Imaging and Behavior
- 7,8-Dihydroxyflavone Ameliorates Cognitive Impairment by Inhibiting Expression of Tau Pathology in ApoE-Knockout MiceYang Tan, Shuke Nie, Wende Zhu, Fang Liu, Hailong Guo, Jiewen Chu, Xue Bin Cao, Xingjun Jiang, Yunjian Zhang, Yuzhen Li · 2016 · Frontiers in Aging Neuroscience
- Deciphering the role of APOE in cerebral amyloid angiopathy: from genetic insights to therapeutic horizonsHantian Hu, Siqi Wan, Yuetao Hu, Qi Wang, Hanyu Li, Nan Zhang · 2025 · Annals of Medicine
- Cholesterol Metabolism in CNS Diseases: The Potential of SREBP2 and LXR as Therapeutic TargetsWang, Ning-Qi, Sun, Pei-Xiang, Shen, Qi-Qi, Deng, Meng-Yan · 2025 · Molecular Neurobiology
- Apolipoprotein E increases cell association of amyloid-β 40 through heparan sulfate and LRP1 dependent pathwaysPaul W. O'Callaghan, Fredrik Noborn, Dag Sehlin, Jin‐Ping Li, Lars Lannfelt, Ulf Lindahl, Xiao Zhang · 2014 · Amyloid
- Associative Interactions among Zinc, Apolipoprotein E, and Amyloid-β in the Amyloid PathologyShin Bi Oh, Jung Ah Kim, SuJi Park, Joo‐Yong Lee · 2020 · International Journal of Molecular Sciences
- Protein-based HDL subspecies: Rationale and association with cardiovascular disease, diabetes, stroke, and dementiaFrank M. Sacks, Jeremy D. Furtado, Majken K. Jensen · 2022 · Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids
- Effect of seabuckthorn seed protein and its arginine-enriched peptides on combating memory impairment in miceXiping Zhu, Lei Cai, Jinqi Liu, Wen Zhu, Chun Cui, Daofu Ouyang, Jianwen Ye · 2023 · International Journal of Biological Macromolecules
- Evidence that Alzheimer’s Disease Is a Disease of Competitive Synaptic Plasticity Gone AwryZhen Huang · 2024 · Journal of Alzheimer s Disease
- Potential Therapeutic Implications of Gelsolin in Alzheimer's DiseaseLina Ji, Xi Zhao, Zichun Hua · 2015 · Journal of Alzheimer s Disease
- Transcriptional regulation of APP by apoE: To boldly go where no isoform has gone beforeLiying Corinne Lee, Michele Q. L. Goh, Edward H. Koo · 2017 · BioEssays
- Characterization of a 3xTg‐AD mouse model of Alzheimer's disease with the senescence accelerated mouse prone 8 (SAMP8) backgroundJessica Virgili, Meryem Lebbadi, Cyntia Tremblay, Isabelle St‐Amour, Caroline Pierrisnard, Audrey Faucher-Genest, Vincent Émond, Carl Julien, Frédéric Calon · 2018 · Synapse
- The Impact of Phytosterols on the Healthy and Diseased BrainTess Dierckx, Jeroen F. J. Bogie, Jerome J. A. Hendriks · 2018 · Current Medicinal Chemistry
- Assessing Neuroprotective Agents for Aβ-Induced NeurotoxicityKelly H. Forest, Robert A. Nichols · 2019 · Trends in Molecular Medicine
- Apolipoprotein E impairs amyloid‐β fibril elongation and maturationTohidul Islam, Anna L. Gharibyan, Solmaz Surano, Nina Pettersson, Kristoffer Brännström, Isabell Hedberg, Merit‐Miriam Virta, Linnea Olofsson, Anders Olofsson · 2019 · FEBS Journal
- Hormonal modulators of glial ABCA1 and apoE levelsJianjia Fan, Yoko Shimizu, Jeniffer Y. Chan, Anna Wilkinson, Ayaka Ito, Peter Tontonoz, Edie M. Dullaghan, Liisa A.M. Galea, Tom A. Pfeifer, Cheryl Lea Wellington · 2013 · Journal of Lipid Research
- Indole Compound NC009-1 Augments APOE and TRKA in Alzheimer’s Disease Cell and Mouse Models for Neuroprotection and Cognitive ImprovementYi-Chun Chen, Ya‐Jen Chiu, Chih‐Hsin Lin, Wen‐Chuin Hsu, Jia-Lu Wu, Chen-Hsiang Huang, Chia-Wei Lin, Ching‐Fa Yao, Hei-Jen Huang, Yen‐Shi Lo et al. · 2019 · Journal of Alzheimer s Disease
- Association of aBACE1Gene Polymorphism with Parkinson’s Disease in a Norwegian PopulationJohannes Lange, Kristin Aaser Lunde, Camilla Sletten, Simon Geir Møller, Ole‐Bjørn Tysnes, Guido Werner Alves, Jan Petter Larsen, Jodi Maple‐Grødem · 2015 · Parkinson s Disease
- Study of Exosomes Shed New Light on Physiology of AmyloidogenesisGuillaume van Niel · 2016 · Cellular and Molecular Neurobiology
- Cerebrospinal Fluid Proteins as Regulators of Beta‐amyloid Aggregation and ToxicityKayla M. Pate, Regina M. Murphy · 2017 · Israel Journal of Chemistry
- Cognitive functions, lipid profile, and Apolipoprotein E gene polymorphism in postmenopausal womenIwona Bojar, Jakub Owoc, Alfred Owoc, Angelina Wójcik‐Fatla, Grzegorz Raszewski, Jaroslav Stančiak, Dorota Raczkiewicz · 2015 · Annals of Agricultural and Environmental Medicine
- Selective modulation of amyloid‐β peptide degradation by flurbiprofen, fenofibrate, and related compounds regulates Aβ levelsSamer O. Abdul‐Hay, Praneeth D. Edirisinghe, Gregory R. J. Thatcher · 2009 · Journal of Neurochemistry
- Apolipoprotein E-dependent load of white matter hyperintensities in Alzheimer’s disease: a voxel-based lesion mapping studyKatrin Morgen, Michael Schneider, Lutz Frölich, Heike Tost, Michael M. Plichta, Heike Kölsch, Fabian Rakebrandt, Otto Rienhoff, Frank Jessen, Oliver Peters et al. · 2015 · Alzheimer s Research & Therapy
- TRPC Channels and Alzheimer’s DiseaseRui Lu, He Qian, Junfeng Wang · 2017 · Advances in experimental medicine and biology
- Sterol Lipid Metabolism in Down Syndrome Revisited: Down Syndrome Is Associated with a Selective Reduction in Serum Brassicasterol LevelsGavin Tansley, Daniel Thomas Holmes, Dieter Lütjohann, Elizabeth Head, Cheryl Lea Wellington · 2012 · Current Gerontology and Geriatrics Research
- Synthesis and Biological Evaluation of Hydroxylated Monocarbonyl Curcumin Derivatives as Potential Inducers of Neprilysin ActivityDimitris Matiadis, See-Ting Ng, Eric H.-L. Chen, Georgia Nigianni, Veroniki P. Vidali, Aleksander Canko, Rita P.‐Y. Chen, Marina Sagnou · 2021 · Biomedicines
- It Is Time to Study Overlapping Molecular and Circuit Pathophysiologies in Alzheimer’s and Lewy Body Disease SpectraNoritaka Wakasugi, Takashi Hanakawa · 2021 · Frontiers in Systems Neuroscience
- Revisiting APP secretases: an overview on the holistic effects of retinoic acid receptor stimulation in APP processingJosé J. M. Vitória, Diogo Trigo, Odete A. B. da Cruz e Silva · 2022 · Cellular and Molecular Life Sciences
- Retinoid X Receptor Alpha Nitro-ligand Z-10 and Its Optimized Derivative Z-36 Reduce β-Amyloid Plaques in Alzheimer’s Disease Mouse ModelGaoang Ren, Wei Bao, Zhiping Zeng, Weidong Zhang, Ce Shang, Maosi Wang, Ying Su, Xiao-kun Zhang, Hu Zhou · 2018 · Molecular Pharmaceutics
- ApoE and clusterin CSF levels influence associations between APOE genotype and changes in CSF tau, but not CSF Aβ42, levels in non-demented elderlyRosalinde E.R. Slot, Maartje I. Kester, Argonde C. van Harten, Wesley Jongbloed, Femke H. Bouwman, Charlotte Elisabeth Teunissen, Philip Scheltens, Wiesje M. van der Flier, Robert Veerhuis · 2019 · Neurobiology of Aging
- The Associations of Cerebrospinal Fluid ApoE and Biomarkers of Alzheimer’s Disease: Exploring Interactions With SexYing Liu, Jinghui Song, Wei Xu, Xiao‐He Hou, Jieqiong Li, Jin‐Tai Yu, Lan Tan, Song Chi, and Alzheimer’s Disease Neuroimaging Initiative · 2021 · Frontiers in Neuroscience
- Endogenous Human Proteins Interfering with Amyloid FormationAnna L. Gharibyan, Sanduni Wasana Jayaweera, Manuela Lehmann, Intissar Anan, Anders Olofsson · 2022 · Biomolecules
- Cognitive and Neuropsychological Profiles in Alzheimer’s Disease and Primary Age-Related Tauopathy and the Influence of Comorbid NeuropathologiesJamie M. Walker, Mitzi M. Gonzales, William F. Goette, Kurt W. Farrell, Charles L. White, John F. Crary, Timothy E. Richardson · 2023 · Journal of Alzheimer s Disease
- Analysis of Genome-Wide Association Study (GWAS) data looking for replicating signals in Alzheimer's disease (AD).Hui Shi, Christopher Medway, James M. Bullock, Kristelle S. Brown, Noor A Kalsheker, Kevin Morgan · 2010 · PubMed Central
- Daily rhythms of cognition-related factors are modified in an experimental model of Alzheimer’s diseaseLorena Navigatore-Fonzo, Andrea Castro, Verónica Pignataro, Marisa Hilda Garraza, Marilina Casais, Ana Cecilia Anzulovich · 2017 · Brain Research
- Insulin Action in the Brain and the Pathogenesis of Alzheimer’s DiseaseC. Ronald Kahn, Ryo Suzuki · 2010 · Research and perspectives in Alzheimer's disease
- Enlargement of Aβ aggregates through chemokine-dependent microglial clusteringWei-Chao Huang, Feng-Chang Yen, Young‐Ji Shiao, Feng‐Shiun Shie, Jin-Lieh Chan, Cheng-Ning Yang, Yen-Jen Sung, Fong-Lee Huang, Huey-Jen Tsay · 2009 · Neuroscience Research
- The Pathological Cross Talk Between Apolipoprotein E and Amyloid-β Peptide in Alzheimer's Disease: Emerging Gene-Based Therapeutic ApproachesSandra Iurescia, Daniela Piergili Fioretti, Francesca Mangialasche, Monica Rinaldi · 2010 · Journal of Alzheimer s Disease
- Engineered Stem Cell Membrane-Coated Nanodrugs for Targeted Therapy of Alzheimer’s DiseaseShuang Sha, Chunbin Sun, Xiaoyu Gao, Wangyu Bi, Hongyu Chen, Weijie Ren, Lei Wang, Enli Luo, Cencan Xing, Hongwu Du · 2025 · ACS Applied Materials & Interfaces
- APOE Lipoprotein Particles: Pathophysiology, Therapy, and the Crosstalk in Alzheimer’s Disease and Cardiovascular DiseaseЧан Лю, Juan Liu, Yanyang Wang, Shang-Fu Xu, Li-Mei Yu · 2025 · Molecular Neurobiology
- Depression and APOEε4 Status in Individuals with Subjective Cognitive Decline: A Meta-AnalysisYueping Huang, Jujun Xue, Chao Li, Xi Chen, Hongjuan Fu, Teng Fei, Peng-xiang Bi · 2020 · Psychiatry Investigation
- Alzheimer’s disease pathogenetic progression is associated with changes in regulated retained introns and editing of circular RNAsKarol Andrea Arizaca Maquera, Justin Ralph Welden, Giorgi Margvelani, Sandra C. Miranda Sardón, Samantha N. Hart, Noémie Robil, Alvaro Gonzalo Hernandez, Pierre de la Grange, Peter T. Nelson, Stefan Stamm · 2023 · Frontiers in Molecular Neuroscience
- Failure, Success, and Future Direction of Alzheimer Drugs Targeting Amyloid‐β Cascade: Pros and Cons of Chemical and Biological ModalitiesJimin Kim, Hanna Jeon, Hye Yun Kim, Young Soo Kim · 2023 · ChemBioChem
- Retracted: Advances in the physiological and pathological implications of cholesterolVíctor Cortés, Dolores Busso, Pablo Mardones, Alberto Maiz G, Antonio Arteaga, Flavio O. Nervi, Attilio Rigotti · 2013 · Biological reviews/Biological reviews of the Cambridge Philosophical Society · Retracted
- Impaired plasmalogen synthesis dysregulates liver X receptor-dependent transcription in cerebellumMasanori Honsho, Fabian Dorninger, Yuichi Abe, Daiki Setoyama, Ryohei Ohgi, Takeshi Uchiumi, Dongchon Kang, Johannes Berger, Yukio Fujiki · 2019 · The Journal of Biochemistry
- Bexarotene Impairs Cognition and Produces Hypothyroidism in a Mouse Model of Down Syndrome and Alzheimer’s DiseaseVerónica Vidal, Alba Puente, Susana García-Cerro, María Teresa García‐Unzueta, Noemı́ Rueda, Javier Riancho, Carmen Martínez‐Cué · 2021 · Frontiers in Pharmacology
- Liver X receptor agonist T0901317 reduces neuropathological changes and improves memory in mouse models of experimental dementiaRupinder Kaur Sodhi, Nirmal Singh · 2014 · European Journal of Pharmacology
- Fatty acid-based lipidomics and membrane remodeling induced by apoE3 and apoE4 in human neuroblastoma cellsPrasinou, Paraskevi, Dafnis, Ioannis, Giacometti, Giorgia, Ferreri, Carla, Chroni, Angeliki, Chatgilialoglu, Chryssostomos · 2017 · Biochimica et Biophysica Acta (BBA) - Biomembranes
- Genetic and environmental risk factors for dementia in African adults: A systematic reviewDavid Mawutor Donkor, Esther Marfo, Ansumana Sandy Bockarie, Edward Jenner Tettevi, Maxwell Hubert Antwi, John Dogah, George Nkrumah Osei, David Larbi Simpong · 2025 · Alzheimer s & Dementia
- Tract Based Spatial Statistic Reveals No Differences in White Matter Microstructural Organization between Carriers and Non-Carriers of the APOE ɛ4 and ɛ2 Alleles in Young Healthy AdolescentsFlavio Dell’Acqua, Wasim Khan, Natalie Gottlieb, Vincent Giampietro, Cedric E. Ginestet, David Bouls, Stephen Newhouse, Richard Dobson, Tobias Banaschewski, Gareth J. Barker et al. · 2015 · Journal of Alzheimer s Disease
- Decreased Inter-Hemispheric Functional Connectivity in Cognitively Intact Elderly APOE ɛ 4 Carriers: A Preliminary StudyXiao Luo, Tiantian Qiu, Xiaojun Xu, Peiyu Huang, Quanquan Gu, Zhujing Shen, Xinfeng Yu, Yunlu Jia, Xiaojun Guan, Ruirui Song et al. · 2016 · Journal of Alzheimer s Disease
- RARβ Agonist Drug (C286) Demonstrates Efficacy in a Pre-clinical Neuropathic Pain Model Restoring Multiple Pathways via DNA Repair MechanismsMaria Beatriz C.V. Goncalves, Julien Moehlin, Earl E. Clarke, John Grist, Carl Hobbs, Antony M. Carr, Julian Jack, Marco Antonio Mendoza-Parra, Jonathan P. T. Corcoran · 2019 · iScience
- CSF cutoffs for MCI due to AD depend on APOEε4 carrier statusMoira Marizzoni, Clarissa Ferrari, Claudio Babiloni, Diego Albani, Frederik Barkhof, Libera Cavaliere, Mira Didic, Gianluigi Forloni, Federica Fusco, Samantha Galluzzi et al. · 2019 · Neurobiology of Aging
- MSR1 and NEP Are Correlated with Alzheimer’s Disease Amyloid Pathology and Apolipoprotein AlterationsJustin Miron, Cynthia Picard, Anne Labonté, Daniel S. Auld, Judes Poirier · 2022 · Journal of Alzheimer s Disease
- Curcumin ameliorates lipid metabolic disorder and cognitive dysfunction via the ABCA1 transmembrane transport system in APP/PS1 double transgenic miceMingyuan Tian, Fanlin Zhou, Zhipeng Teng, Chen Wang, Xiong Zhang, Yangyang Wang, Yu Li · 2021 · Journal of Integrative Neuroscience
- A review of imaging genetics in Alzheimer's diseaseXin Yu, Jinhua Sheng, Miao Miao, Luyun Wang, Ze Xiao Yang, He Huang · 2022 · Journal of Clinical Neuroscience
- Deciphering an interplay of proteins associated with amyloid β 1-42 peptide and molecular mechanisms of Alzheimer’s diseaseLuis Fernando Hernández-Zimbrón, Selva Rivas-Arancibia · 2014 · Reviews in the Neurosciences
- Postmenopausal cognitive changes and androgen levels in the context of apolipoprotein E polymorphismIwona Bojar, Jarosław Pinkas, Mariusz Gujski, Alfred Owoc, Dorota Raczkiewicz, Kasia Gustaw Rothenberg · 2016 · Archives of Medical Science
- Effects of an Aβ-antibody fragment on Aβ aggregation and astrocytic uptake are modulated by apolipoprotein E and J mimetic peptidesLaia Montoliu‐Gaya, Sandra D. Mulder, Robert Veerhuis, Sandra Villegas · 2017 · PLoS ONE
- Development of new treatments for Alzheimer’s disease based on the modulation of translocator protein (TSPO)Bruno Dutra Arbo, Maria Flávia Marques Ribeiro, Luis Miguel García‐Segura · 2019 · Ageing Research Reviews