ApoE Promotes the Proteolytic Degradation of Aβ

Jiang, Qingguang, Lee, C.Y. Daniel, Mandrekar, Shweta, Wilkinson, Brandy, Cramer, Paige, Zelcer, Noam, Mann, Karen, Lamb, Bruce +9 more·2008·Neuron

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Items 201–300 of 876

  1. ABCA7 Mediates Phagocytic Clearance of Amyloid-β in the Brain
    YuHong Fu, Jen-Hsiang T. Hsiao, George Paxinos, Glenda Margaret Halliday, Woojin Scott Kim · 2016 · Journal of Alzheimer s Disease
  2. Inflammation in transgenic mouse models of neurodegenerative disorders
    Schwab, Claudia, Klegeris, Andis, McGeer, Patrick. L. · 2010 · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease
  3. Greasing the wheels of Aβ clearance in Alzheimer's Disease: The role of lipids and apolipoprotein E
    Fan, Jianjia, Donkin, James, Wellington, Cheryl · 2009 · BioFactors
  4. Protective effect of the phosphodiesterase III inhibitor cilostazol on amyloid β-induced cognitive deficits associated with decreased amyloid β accumulation
    Sun Haeng Park, Ji Hyun Kim, Sun Sik Bae, Ki Whan Hong, Dong‐Seok Lee, Jae Yoon Leem, Byung Tae Choi, Hwa Kyoung Shin · 2011 · Biochemical and Biophysical Research Communications
  5. The effect of amyloid associated proteins on the expression of genes involved in amyloid-β clearance by adult human astrocytes.
    S. Mulder, R. Veerhuis, M. Blankenstein, H. Nielsen · 2012 · Experimental Neurology
  6. Apolipoprotein E receptors in the nervous system
    Joachim Herz · 2009 · Current Opinion in Lipidology
  7. Genetics of Alzheimer’s Disease
    Perry G. Ridge, Mark Ebbert, John S. K. Kauwe · 2013 · BioMed Research International
  8. Nuclear receptors in neurodegenerative diseases
    Skerrett, Rebecca, Malm, Tarja, Landreth, Gary · 2014 · Neurobiology of Disease
  9. Human ApoE Isoforms Differentially Modulate Glucose and Amyloid Metabolic Pathways in Female Brain: Evidence of the Mechanism of Neuroprotection by ApoE2 and Implications for Alzheimer’s Disease Prevention and Early Intervention
    Keeney, Jeriel Thomas-Richard, Ibrahimi, Shaher, Zhao, Liqin · 2015 · Journal of Alzheimer's Disease
  10. Lipid metabolism and neuroinflammation in Alzheimer’s disease: a role for liver X receptors
    Kang, Jihong, Rivest, Serge · 2012 · Endocrine Reviews
  11. Amyloid-β Pathology and APOE Genotype Modulate Retinoid X Receptor Agonist Activity in Vivo
    Leon M. Tai, Kevin P. Koster, Jia Luo, Sue Lee, Yue‐ting Wang, Nicole C. Collins, Manel Ben Aissa, Gregory R. J. Thatcher, Mary Jo LaDu · 2014 · Journal of Biological Chemistry
  12. Genetics and genomics of human ageing
    Heather E. Wheeler, Stuart K. Kim · 2010 · Philosophical Transactions of the Royal Society B Biological Sciences
  13. ABC Transporters Are Key Players in Alzheimer’s Disease
    Cátia D. Pereira, Filipa Martins, Jens Wiltfang, Odete A. B. da Cruz e Silva, Sandra Rebelo · 2017 · Journal of Alzheimer s Disease
  14. Apolipoprotein E in Alzheimer’s disease: molecular insights and therapeutic opportunities
    Belaidi, Abdel Ali, Bush, Ashley I., Ayton, Scott · 2025 · Molecular Neurodegeneration
  15. Current Progress on Peroxisome Proliferator-activated Receptor Gamma Agonist as an Emerging Therapeutic Approach for the Treatment of Alzheimer's Disease: An Update
    Mahmood Ahmad Khan, Qamre Alam, Absarul Haque, Mohammad Ashafaq, Mohd Jahir Khan, Ghulam Md Ashraf, Mahboob Ahmad · 2018 · Current Neuropharmacology
  16. Dietary Sargassum fusiforme improves memory and reduces amyloid plaque load in an Alzheimer’s disease mouse model
    Jeroen F. J. Bogie, Cindy Hoeks, Melissa Schepers, Assia Tiane, Ann Cuypers, Frank P. J. Leijten, Yupyn Chintapakorn, Thiti Suttiyut, Surachai Pornpakakul, Dicky Struik et al. · 2019 · Scientific Reports
  17. The relationship between amyloid-beta and brain capillary endothelial cells in Alzheimer’s disease
    Su, Qiang, Guo, Jun-Hong, Zhang, Yan-Li, Wang, Juan, Zhang, Zhi-Na · 2022 · Neural Regeneration Research
  18. Retinoids as potential targets for Alzheimer's disease
    Rupinder Kaur Sodhi, Nirmal Singh · 2014 · Pharmacology Biochemistry and Behavior
  19. SUMO and Alzheimer’s Disease
    Linda Lee, Mikako Sakurai, Shinsuke Matsuzaki, Ottavio Arancio, Paul E. Fraser · 2013 · NeuroMolecular Medicine
  20. Effect of Cholesterol on Membrane Fluidity and Association of Aβ Oligomers and Subsequent Neuronal Damage: A Double-Edged Sword
    Eduardo J. Fernández-Pérez, Fernando J. Sepúlveda, Christian Peters, Denisse Bascuñán, Nicolás Riffo-Lepe, Juliana González-Sanmiguel, Susana A. Sánchez, Robert W. Peoples, Benjamín Vicente, Luis Gerardo Aguayo · 2018 · Frontiers in Aging Neuroscience
  21. Aβ Internalization by Neurons and Glia
    Amany Mohamed, E Chaves · 2011 · International Journal of Alzheimer s Disease
  22. Blocking the Interaction between Apolipoprotein E and Aβ Reduces Intraneuronal Accumulation of Aβ and Inhibits Synaptic Degeneration
    Kuszczyk, Magdalena A., Sanchez, Sandrine, Pankiewicz, Joanna, Kim, Jungsu, Duszczyk, Malgorzata, Guridi, Maitea, Asuni, Ayodeji A., Sullivan, Patrick M., Holtzman, David M., Sadowski, Martin J. · 2013 · The American Journal of Pathology
  23. Combined Liver X Receptor/Peroxisome Proliferator-activated Receptor γ Agonist Treatment Reduces Amyloid β Levels and Improves Behavior in Amyloid Precursor Protein/Presenilin 1 Mice
    Rebecca Skerrett, Mateus Paquesse Pellegrino, Brad T. Casali, Laura Taraboanta, Gary E. Landreth · 2015 · Journal of Biological Chemistry
  24. Lipoproteins in the Central Nervous System: From Biology to Pathobiology
    Raulin, Ana-Caroline, Martens, Yuka A., Bu, Guojun · 2022 · Annual Review of Biochemistry
  25. Restored degradation of the Alzheimer’s amyloid‐β peptide by targeting amyloid formation
    Peter John Crouch, Deborah J. Tew, Tai Du, Diem Nguyen, Aphrodite Caragounis, Gulay Filiz, Rachel E. Blake, Ian Andrew Trounce, Cynthia P.W. Soon, Katrina M. Laughton et al. · 2009 · Journal of Neurochemistry
  26. Impact of Insulin Degrading Enzyme and Neprilysin in Alzheimer’s Disease Biology: Characterization of Putative Cognates for Therapeutic Applications
    N. K. Jha, S. Jha, Dhiraj Kumar, Noopur Kejriwal, Renubala Sharma, R. K. Ambasta, Pravir Kumar · 2015 · Journal of Alzheimer's Disease
  27. The role of glycogen synthase kinase 3 in the early stages of Alzheimers’ disease
    Félix Hernández, Jesús Ávila · 2008 · FEBS Letters
  28. Patient iPSC-Derived Neurons for Disease Modeling of Frontotemporal Dementia with Mutation in CHMP2B
    Yu Zhang, Benjamin Schmid, Nanett Kvist Nikolaisen, Mikkel A. Rasmussen, Blanca I. Aldana, Mikkel Pejstrup Agger, Kirstine Calløe, Tina C. Stummann, Hjalte M. Larsen, Troels T. Nielsen et al. · 2017 · Stem Cell Reports
  29. Neuroprotective astrocyte-derived insulin/insulin-like growth factor 1 stimulates endocytic processing and extracellular release of neuron-bound Aβ oligomers
    Jason E. Pitt, Kyle C. Wilcox, Vanessa Tortelli, Luan Pereira Diniz, Maira S. Oliveira, Cassandra Dobbins, Xiaowen Yu, Sathwik Nandamuri, Flávia Carvalho Alcântara Gomes, Nadia DiNunno et al. · 2017 · Molecular Biology of the Cell
  30. The AβCs of Aβ-cleaving Proteases*
    M. Leissring · 2008 · Journal of Biological Chemistry
  31. Mechanisms of Action of Non-Steroidal Anti-Inflammatory Drugs for the Prevention of Alzheimers Disease
    Greg M. Cole, Sally Ann Frautschy · 2010 · CNS & Neurological Disorders - Drug Targets
  32. Treatment with bexarotene, a compound that increases apolipoprotein-E, provides no cognitive benefit in mutant APP/PS1 mice
    LaClair, Katherine D, Manaye, Kebreten F, Lee, Dexter L, Allard, Joanne S, Savonenko, Alena V, Troncoso, Juan C, Wong, Philip C · 2013 · Molecular Neurodegeneration
  33. Amyloid-beta and Alzheimer’s disease: the role of neprilysin-2 in amyloid-beta clearance
    Robert A. Marr, Daniel M. Hafez · 2014 · Frontiers in Aging Neuroscience
  34. ABC transporters: human disease and pharmacotherapeutic potential
    Jonathan M. Moore, Eric L. Bell, Robert O Hughes, Alastair S. Garfield · 2022 · Trends in Molecular Medicine
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    T. Vanmierlo, J. Bogie, Jo Mailleux, J. Vanmol, D. Lütjohann, M. Mulder, Jerome J. A. Hendriks · 2015 · Progress in lipid research
  36. Overlapped Metabolic and Therapeutic Links between Alzheimer and Diabetes
    Waqar Ahmad · 2012 · Molecular Neurobiology
  37. The Complex Role of Apolipoprotein E in Alzheimer’s Disease: an Overview and Update
    Laura Mahoney‐Sanchez, Abdel Ali Belaidi, Ashley Ian Bush, Scott Ayton · 2016 · Journal of Molecular Neuroscience
  38. Amyloid β inhibits retinoic acid synthesis exacerbating A lzheimer disease pathology which can be attenuated by an retinoic acid receptor α agonist
    Maria Beatriz C.V. Goncalves, Earl E. Clarke, Carl Hobbs, Tony Malmqvist, Robert M. J. Deacon, Julian Jack, Jonathan P. T. Corcoran · 2013 · European Journal of Neuroscience
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    Huntington Potter, Thomas Wısnıewskı · 2012 · International Journal of Alzheimer s Disease
  40. APOE effects on regional tau in preclinical Alzheimer’s disease
    Young, Christina B., Johns, Emily, Kennedy, Gabriel, Belloy, Michael E., Insel, Philip S., Greicius, Michael D., Sperling, Reisa A., Johnson, Keith A., Poston, Kathleen L., Mormino, Elizabeth C. et al. · 2023 · Molecular Neurodegeneration
  41. APOE ε4 moderates amyloid-related memory decline in preclinical Alzheimer's disease
    Yen Ying Lim, Victor L. Villemagne, Robert H. Pietrzak, David J. Ames, Kathryn A. Ellis, Karra Harrington, Peter Jeffrey Snyder, Ralph Nigel Martins, Colin Louis Masters, Christopher C. Rowe et al. · 2014 · Neurobiology of Aging
  42. The Triggering Receptor Expressed on Myeloid Cells 2: A Molecular Link of Neuroinflammation and Neurodegenerative Diseases
    Walter, Jochen · 2016 · Journal of Biological Chemistry
  43. Lipid Metabolism and Glial Lipoproteins in the Central Nervous System
    Hayashi, Hideki · 2011 · Biological and Pharmaceutical Bulletin
  44. DNA methylation alterations in Alzheimer’s disease
    Amy S. Yokoyama, John C. Rutledge, Valentina Medici · 2017 · Current Zoology
  45. Deciphering cell–cell communication at single-cell resolution for spatial transcriptomics with subgraph-based graph attention network
    Wenyi Yang, Pingping Wang, Shouping Xu, Tao Wang, Meng Luo, Yideng Cai, Chang Xu, Guangfu Xue, Jinhao Que, Qian Ding et al. · 2024 · Nature Communications
  46. Biomarkers and therapeutic strategies targeting microglia in neurodegenerative diseases: current status and future directions
    Min‐Young Noh, Hyuk Sung Kwon, Min‐Soo Kwon, Minyeop Nahm, Hee Kyung Jin, Jae‐sung Bae, Seung Hyun Kim · 2025 · Molecular Neurodegeneration
  47. Abnormal amyloid beta metabolism in systemic abnormalities and Alzheimer’s pathology: Insights and therapeutic approaches from periphery
    Ullah, Rahat, Park, Tae Ju, Huang, Xu, Kim, Myeong Ok · 2021 · Ageing Research Reviews
  48. Magnolol alleviates Alzheimer's disease-like pathology in transgenic C. elegans by promoting microglia phagocytosis and the degradation of beta-amyloid through activation of PPAR-γ
    Zhishen Xie, Jianping Zhao, Hui Wang, Yali Jiang, Qiaoling Yang, Yu Fu, Huahui Zeng, Christian Hölscher, Jiangyan Xu, Zhenqiang Zhang · 2020 · Biomedicine & Pharmacotherapy
  49. Towards Understanding the Roles of Heparan Sulfate Proteoglycans in Alzheimer’s Disease
    Gan-lin Zhang, Xiao Zhang, Xiaomin Wang, Jin‐Ping Li · 2014 · BioMed Research International
  50. Remembering your A, B, C's: Alzheimer's disease and ABCA1
    Lewandowski, Cutler T., Laham, Megan S., Thatcher, Gregory R.J. · 2022 · Acta Pharmaceutica Sinica B
  51. Small-molecule BACE1 inhibitors: a patent literature review (2006 – 2011)
    Gary D. Probst, Ying‐zi Xu · 2012 · Expert Opinion on Therapeutic Patents
  52. Integrative neurobiology of metabolic diseases, neuroinflammation, and neurodegeneration
    van Dijk, Gertjan, van Heijningen, Steffen, Reijne, Aaffien C., Nyakas, Csaba, van der Zee, Eddy A., Eisel, Ulrich L. M. · 2015 · Frontiers in Neuroscience
  53. Plasma apolipoprotein E levels and risk of dementia: A Mendelian randomization study of 106,562 individuals
    Rasmussen, Katrine L., Tybjærg‐Hansen, Anne, Nordestgaard, Børge G., Frikke‐Schmidt, Ruth · 2018 · Alzheimer's & Dementia
  54. Reduction of cholesterol synthesis in the mouse brain does not affect amyloid formation in Alzheimer's disease, but does extend lifespan
    Halford, Rebekkah W., Russell, David W. · 2009 · Proceedings of the National Academy of Sciences
  55. Protective Effects of Anthocyanins against Amyloid β-Peptide-Induced Damage in Neuro-2A Cells
    Ping‐Hsiao Shih, Chih‐Hsiung Wu, Chi‐Tai Yeh, Gow‐Chin Yen · 2011 · Journal of Agricultural and Food Chemistry
  56. Loss of Interleukin Receptor-Associated Kinase 4 Signaling Suppresses Amyloid Pathology and Alters Microglial Phenotype in a Mouse Model of Alzheimer's Disease
    Brent Cameron, Wayne Tse, Raza Lamb, Xiaoxia Li, Bruce T. Lamb, Gary E. Landreth · 2012 · Journal of Neuroscience
  57. Therapeutic potential of nuclear receptor agonists in Alzheimer's disease
    Miguel Moutinho, Gary E. Landreth · 2017 · Journal of Lipid Research
  58. Signaling Mechanisms of Selective PPARγ Modulators in Alzheimer’s Disease
    Manoj Govindarajulu, Priyanka D. Pinky, Jenna Bloemer, Nila Ghanei, Vishnu D. Suppiramaniam, Rajesh Amin · 2018 · PPAR Research
  59. Rodent Models of Amyloid-Beta Feature of Alzheimer’s Disease: Development and Potential Treatment Implications
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  60. Apolipoprotein E Genotype Affects Size of ApoE Complexes in Cerebrospinal Fluid
    Heinsinger, Nicolette Mary, Gachechiladze, Mariam Alexandra, Rebeck, G. William · 2016 · Journal of Neuropathology & Experimental Neurology
  61. Response to Comments on “ApoE-Directed Therapeutics Rapidly Clear β-Amyloid and Reverse Deficits in AD Mouse Models”
    Gary E. Landreth, Paige E. Cramer, Mitchell M. Lakner, John R. Cirrito, Daniel W. Wesson, Kurt R. Brunden, Donald A. Wilson · 2013 · Science
  62. Apolipoprotein E associated with reconstituted high‐density lipoprotein‐like particles is protected from aggregation
    Hubin, Ellen, Verghese, Philip B., van Nuland, Nico, Broersen, Kerensa · 2019 · FEBS Letters
  63. Shifting equilibriums in Alzheimer’s disease: the complex roles of microglia in neuroinflammation, neuronal survival and neurogenesis
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  64. Preparation of fluorescently‐labeled amyloid‐beta peptide assemblies: the effect of fluorophore conjugation on structure and function
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  66. Aneuploidy, chromosomal missegregation, and cell cycle reentry in Alzheimer's disease
    Cezary Żekanowski, Urszula Wojda · 2009 · Acta Neurobiologiae Experimentalis
  67. A randomized controlled study to evaluate the effect of bexarotene on amyloid‐β and apolipoprotein E metabolism in healthy subjects
    Ghosal, Kaushik, Haag, Michael, Verghese, Philip B., West, Tim, Veenstra, Tim, Braunstein, Joel B., Bateman, Randall J., Holtzman, David M., Landreth, Gary E. · 2016 · Alzheimer's & Dementia: Translational Research & Clinical Interventions
  68. Disrupted functional and structural networks in cognitively normal elderly subjects with the APOE ɛ4 allele
    Chen, Yaojing, Chen, Kewei, Zhang, Junying, Li, Xin, Shu, Ni, Wang, Jun, Zhang, Zhanjun, Reiman, Eric M · 2015 · Neuropsychopharmacology
  69. ACAT inhibition and amyloid beta reduction
    Raja Bhattacharyya, Dora M. Kovacs · 2010 · Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids
  70. CSF Apo-E levels associate with cognitive decline and MRI changes
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  71. Brain regional correlation of amyloid-β with synapses and apolipoprotein E in non-demented individuals: potential mechanisms underlying regional vulnerability to amyloid-β accumulation
    M. Shinohara, R. Petersen, D. Dickson, Guo-Jun Bu · 2013 · Acta Neuropathologica
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