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Cited by 443

MicroRNA-Mediated Control of Oligodendrocyte Differentiation

Zhao, Xianghui, He, Xuelian, Han, Xiaolei, Yu, Yang, Ye, Feng, Chen, Ying, Hoang, ThaoNguyen, Xu, Xiaomei +5 more·2010·Neuron
DOI 10.1016/j.neuron.2010.02.018PMC PMC2855245
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Crossref · 10.1016/j.neuron.2010.02.018

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  • miR-338-3p induces maturation and differentiation of spinal cord oligodendrocyte precursors by repressing Sox5 and Hes6.

    “MiR-338-3p is also expressed in spinal cord oligodendrocytes, where it exerts a related effect, inducing maturation and differentiation of precursors into mature oligodendrocytes by repressing Sox5 and Hes6, two maturation-inhibiting transcription factors [31, 32].”

    From MiR-338-3p regulates neuronal maturation and suppresses glioblastoma proliferation. (2017) · cites this paper as [32]

    The Results section reports that miR-338 promotes oligodendrocyte precursor differentiation, and the spinal-cord expression findings support that context. But its target experiments and Discussion identify Sox6 and Hes5—not the claimed Sox5 and Hes6—as the differentiation inhibitors repressed by miR-338. No page number is available in our copy. (LLM, conf=0.86)

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  • The miR-338 cluster is expressed in human OLs.

    “In summary, we provide the first evidence that miR-338 cluster is expressed in human OLs, as previously demonstrated in rodents (Lau et al., 2008; Dugas et al., 2010; Zhao et al., 2010).”

    From Regulation of miRNA 219 and miRNA Clusters 338 and 17-92 in Oligodendrocytes (2012) · cites this paper as Zhao et al., 2010

  • miR-338-3p was approximately 25-fold more abundant in oligodendrocytes than MNs.

    “As expected, miR-338-3p, a miRNA known to be enriched in oligodendrocytes, was ϳ25-fold more abundant in oligodendrocytes than MNs (Zhao et al., 2010;de Faria et al., 2012) (Fig. 2D).”

    From MicroRNA Profiling Reveals Marker of Motor Neuron Disease in ALS Models (2017) · cites this paper as Zhao et al., 2010

  • In vitro culture studies suggest miR-219 is critical for OPC differentiation and acts through suppressing expression of OL differentiation inhibitors, including PDGFRα, Sox6, and Zfp238.

    “In vitro culture studies suggest that miR-219 is critical for OPC differentiation and acts through suppressing expression of OL differentiation inhibitors, including PDGFRα, Sox6, and Zfp238, predicted by computational algorithms (Dugas et al., 2010; Zhao et al., 2010);”

    From miR-219 Cooperates with miR-338 in Myelination and Promotes Myelin Repair in the CNS (2017) · cites this paper as Zhao et al., 2010

  • miR-219 and miR-338 are preferentially and abundantly expressed in mature oligodendrocytes.

    “Among them, miR-219 and miR-338 are preferentially and abundantly expressed in mature OLs (Dugas et al., 2010; Lau et al., 2008; Zhao et al., 2010).”

    From miR-219 Cooperates with miR-338 in Myelination and Promotes Myelin Repair in the CNS (2017) · cites this paper as Zhao et al., 2010

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Cites

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Research works printed but not linked: 45

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Cited by

Sorted by citations

Authors
Zhao, X., He, X., Han, X., Yu, Y., Ye, F., Chen, Y., Hoang, T., Xu, X., Mi, Q.-S., Xin, M., Wang, F., Appel, B., & Lu, Q. R.
Venue
Neuron
Publisher
Elsevier BV
Published
2010-03
Volume
65
Issue
5
Pages
612-626
ISSN
0896-6273
DOI
10.1016/j.neuron.2010.02.018
PMC
PMC2855245
Cited by
443
References
2
Language
en
Licence
Funders
  • National Institutes of Health (NS050389)
  • National Multiple Sclerosis Society (PP0144, RG3978)

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