Reduced expression of glutamate transporters vGluT1, EAAT2 and EAAT4 in learned helpless rats, an animal model of depression

The rat brain in stereotaxic coordinates

Palkovits, M. (1983) · Neuropeptides · doi:10.1016/0143-4179(83)90049-5 · Cited by 28,959 · see citing works

The Rat Brain in Stereotaxic Coordinates

Paxinos, G., & Watson, C. (1983) · Elsevier eBooks · doi:10.1016/c2009-0-63235-9 · Cited by 28,585 · see citing works

Glutamate uptake

Danbolt, N. C. (2001) · Progress in Neurobiology · doi:10.1016/s0301-0082(00)00067-8 · Cited by 4,068 · see citing works

Antidepressant effects of ketamine in depressed patients

Berman, R. M., Cappiello, A., Anand, A., Oren, D. A., Heninger, G. R., Charney, D. S., & Krystal, J. H. (2000) · Biological Psychiatry · doi:10.1016/s0006-3223(99)00230-9 · Cited by 3,856 · see citing works

A randomized trial of an N-methyl-D-aspartate antagonist in treatment-resistant major depression.

Zarate, C. A., Singh, J. B., Carlson, P. J., Brutsche, N. E., Ameli, R., Luckenbaugh, D. A., Charney, D. S., & Manji, H. K. (2006) · Archives of General Psychiatry · doi:10.1001/archpsyc.63.8.856 · Cited by 3,766 · see citing works

The molecular neurobiology of depression

Krishnan, V., & Nestler, E. J. (2008) · Nature · doi:10.1038/nature07455 · Cited by 2,889 · see citing works

Failure to escape traumatic shock.

Seligman, M. E., & Maier, S. F. (1967) · Journal of Experimental Psychology · doi:10.1037/h0024514 · Cited by 1,981 · see citing works

Glial reduction in the subgenual prefrontal cortex in mood disorders

Öngür, D., Drevets, W. C., & Price, J. L. (1998) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.95.22.13290 · Cited by 1,525 · see citing works

β-Lactam antibiotics offer neuroprotection by increasing glutamate transporter expression

Rothstein, J. D., Patel, S., Regan, M. R., Haenggeli, C., Huang, Y. H., Bergles, D. E., Jin, L., Dykes Hoberg, M., Vidensky, S., Chung, D. S., et al. (2005) · Nature · doi:10.1038/nature03180 · Cited by 1,518 · see citing works

A Double-Blind Placebo-Controlled Study of Lamotrigine Monotherapy in Outpatients With Bipolar I Depression

Calabrese, J. R., Bowden, C. L., Sachs, G. S., Ascher, J. A., Monaghan, E., Rudd, G. D., & The Lamictal 602 Study Group (1999) · The Journal of Clinical Psychiatry · doi:10.4088/jcp.v60n0203 · Cited by 1,054 · see citing works

Medial prefrontal cortex determines how stressor controllability affects behavior and dorsal raphe nucleus

Amat, J., Baratta, M. V., Paul, E., Bland, S. T., Watkins, L. R., & Maier, S. F. (2005) · Nature Neuroscience · doi:10.1038/nn1399 · Cited by 931 · see citing works

The role of the hippocampus in the pathophysiology of major depression

Campbell, S., & MacQUEEN, G. M. (2004) · Journal of Psychiatry and Neuroscience · doi:10.1139/jpn.0441 · Cited by 879 · see citing works

Reduced Prefrontal Glutamate/Glutamine and γ-Aminobutyric Acid Levels in Major Depression Determined Using Proton Magnetic Resonance Spectroscopy

Hasler, G., van der Veen, J. W., Tumonis, T., Meyers, N., Shen, J., & Drevets, W. C. (2007) · Archives of General Psychiatry · doi:10.1001/archpsyc.64.2.193 · Cited by 846 · see citing works

Subtype-Specific Alterations of γ-Aminobutyric Acid and Glutamatein Patients With Major Depression

Sanacora, G., Gueorguieva, R. V., Epperson, C. N., Wu, Y., Appel, M., Rothman, D. L., Krystal, J. H., & Mason, G. F. (2004) · Archives of General Psychiatry · doi:10.1001/archpsyc.61.7.705 · Cited by 796 · see citing works

VGLUTs define subsets of excitatory neurons and suggest novel roles for glutamate

Fremeau, R. T., Voglmaier, S., Seal, R. P., & Edwards, R. H. (2004) · Trends in Neurosciences · doi:10.1016/j.tins.2003.11.005 · Cited by 745 · see citing works

Altered cortical glutamatergic and GABAergic signal transmission with glial involvement in depression

Choudary, P. V., Molnar, M., Evans, S. J., Tomita, H., Li, J., Vawter, M. P., Myers, R., Bunney, W. E., Akil, H., Watson, S. J., et al. (2005) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0507901102 · Cited by 653 · see citing works

Glial Loss in the Prefrontal Cortex Is Sufficient to Induce Depressive-like Behaviors

Banasr, M., & Duman, R. S. (2008) · Biological Psychiatry · doi:10.1016/j.biopsych.2008.06.008 · Cited by 606 · see citing works

Stress Preferentially Increases Extraneuronal Levels of Excitatory Amino Acids in the Prefrontal Cortex: Comparison to Hippocampus and Basal Ganglia

Moghaddam, B. (1993) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.1993.tb13387.x · Cited by 567 · see citing works

Glutamate and GABA systems as targets for novel antidepressant and mood-stabilizing treatments

Krystal, J. H., Sanacora, G., Blumberg, H., Anand, A., Charney, D. S., Marek, G., Epperson, C. N., Goddard, A., & Mason, G. F. (2002) · Molecular Psychiatry · doi:10.1038/sj.mp.4001021 · Cited by 553 · see citing works

Glutamate as a therapeutic target in psychiatric disorders

Javitt, D. C. (2004) · Molecular Psychiatry · doi:10.1038/sj.mp.4001551 · Cited by 524 · see citing works

Low glial numbers in the amygdala in major depressive disorder

Bowley, M. P., Drevets, W. C., Öngür, D., & Price, J. L. (2002) · Biological Psychiatry · doi:10.1016/s0006-3223(02)01404-x · Cited by 503 · see citing works

The chemical biology of clinically tolerated NMDA receptor antagonists

Chen, H.-S. V., & Lipton, S. A. (2006) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.2006.03991.x · Cited by 475 · see citing works

Untitled work

(2005) · PubMed · Cited by 470 · see citing works

The validity of animal models of predisposition to depression

Willner, P., & Mitchell, P. J. (2002) · Behavioural Pharmacology · doi:10.1097/00008877-200205000-00001 · Cited by 430 · see citing works

Glutamate and Depression: Clinical and Preclinical Studies

PAUL, I. A., & SKOLNICK, P. (2003) · Annals of the New York Academy of Sciences · doi:10.1196/annals.1300.016 · Cited by 408 · see citing works

Molecular pharmacology of glutamate transporters, EAATs and VGLUTs

Shigeri, Y., Seal, R. P., & Shimamoto, K. (2004) · Brain Research Reviews · doi:10.1016/j.brainresrev.2004.04.004 · Cited by 391 · see citing works

Specificity of the learned helplessness model of depression

Sherman, A. D., Sacquitne, J. L., & Petty, F. (1982) · Pharmacology Biochemistry and Behavior · doi:10.1016/0091-3057(82)90451-8 · Cited by 391 · see citing works

A Double-Blind, Placebo-Controlled Study of Memantine in the Treatment of Major Depression

Zarate, C. A., Singh, J. B., Quiroz, J. A., De Jesus, G., Denicoff, K. K., Luckenbaugh, D. A., Manji, H. K., & Charney, D. S. (2006) · American Journal of Psychiatry · doi:10.1176/appi.ajp.163.1.153 · Cited by 387 · see citing works

Removing Obstacles in Neuroscience Drug Discovery: The Future Path for Animal Models

Markou, A., Chiamulera, C., Geyer, M. A., Tricklebank, M., & Steckler, T. (2009) · Neuropsychopharmacology · doi:10.1038/npp.2008.173 · Cited by 328 · see citing works

An Open-Label Trial of Riluzole in Patients With Treatment-Resistant Major Depression

Zarate, C. A., Payne, J. L., Quiroz, J. A., Sporn, J., Denicoff, K. K., Luckenbaugh, D. A., Charney, D. S., & Manji, H. K. (2004) · American Journal of Psychiatry · doi:10.1176/appi.ajp.161.1.171 · Cited by 324 · see citing works

Beyond Monoamines: Glutamatergic Function in Mood Disorders

Kugaya, A., & Sanacora, G. (2005) · CNS Spectrums · doi:10.1017/s1092852900010403 · Cited by 291 · see citing works

Stress models of depression: forming genetically vulnerable strains

Henn, F. A., & Vollmayr, B. (2005) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2005.03.019 · Cited by 274 · see citing works

Amino Acid Neurotransmitters Assessed by Proton Magnetic Resonance Spectroscopy: Relationship to Treatment Resistance in Major Depressive Disorder

Price, R. B., Shungu, D. C., Mao, X., Nestadt, P., Kelly, C., Collins, K. A., Murrough, J. W., Charney, D. S., & Mathew, S. J. (2009) · Biological Psychiatry · doi:10.1016/j.biopsych.2008.10.025 · Cited by 270 · see citing works

An open-label trial of the glutamate-modulating agent riluzole in combination with lithium for the treatment of bipolar depression

Zarate, C. A., Quiroz, J. A., Singh, J. B., Denicoff, K. D., Jesus, G. D., Luckenbaugh, D. A., Charney, D. S., & Manji, H. K. (2005) · Biological Psychiatry · doi:10.1016/j.biopsych.2004.11.023 · Cited by 257 · see citing works

Learned helplessness in the rat: improvements in validity and reliability

Vollmayr, B., & Henn, F. A. (2001) · Brain Research Protocols · doi:10.1016/s1385-299x(01)00067-8 · Cited by 238 · see citing works

Presynaptic regulation of astroglial excitatory neurotransmitter transporter GLT1

Yang, Y., Gozen, O., Watkins, A., Lorenzini, I., Lepore, A., Gao, Y., Vidensky, S., Brennan, J., Poulsen, D., Won Park, J., et al. (2009) · Neuron · doi:10.1016/j.neuron.2009.02.010 · Cited by 237 · see citing works

The role of glutamate in mood disorders: Results from the ketamine in major depression study and the presumed cellular mechanism underlying its antidepressant effects

Maeng, S., & Zarate, C. A. (2007) · Current Psychiatry Reports · doi:10.1007/s11920-007-0063-1 · Cited by 232 · see citing works

Chronic restraint stress up-regulates GLT-1 mRNA and protein expression in the rat hippocampus: Reversal by tianeptine

Reagan, L. P., Rosell, D. R., Wood, G. E., Spedding, M., Muñoz, C., Rothstein, J. D., & McEwen, B. S. (2004) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0307294101 · Cited by 221 · see citing works

Remodeling of Hippocampal Spine Synapses in the Rat Learned Helplessness Model of Depression

Hajszán, T., Dow, A. L., Warner‐Schmidt, J. L., Szigeti‐Buck, K., Sallam, N. L., Párducz, Á., Leranth, C., & Duman, R. S. (2008) · Biological Psychiatry · doi:10.1016/j.biopsych.2008.09.031 · Cited by 212 · see citing works

Neurogenesis and depression: etiology or epiphenomenon?

Henn, F. A., & Vollmayr, B. (2004) · Biological Psychiatry · doi:10.1016/j.biopsych.2004.04.011 · Cited by 192 · see citing works

Striatal Excitatory Amino Acid Transporter Transcript Expression in Schizophrenia, Bipolar Disorder, and Major Depressive Disorder

Mccullumsmith, R., & Meador-Woodruff, J. (2002) · Neuropsychopharmacology · doi:10.1016/s0893-133x(01)00370-0 · Cited by 189 · see citing works

Differential Expression of Two Glial Glutamate Transporters in the Rat Brain: an In Situ Hybridization Study

Torp, R., Danbolt, N. C., Babaie, E., Bjørås, M., Seeberg, E. C., Storm‐Mathisen, J., & Ottersen, O. P. (1994) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.1994.tb00587.x · Cited by 186 · see citing works

Behavioral Stress Enhances Hippocampal CA1 Long-Term Depression through the Blockade of the Glutamate Uptake

Yang, C., Huang, C., & Hsu, K. (2005) · Journal of Neuroscience · doi:10.1523/jneurosci.0406-05.2005 · Cited by 181 · see citing works

Region specific decrease in glial fibrillary acidic protein immunoreactivity in the brain of a rat model of depression

Gosselin, R., Gibney, S. M., O’Malley, D., Dinan, T. G., & Cryan, J. F. (2009) · Neuroscience · doi:10.1016/j.neuroscience.2008.10.018 · Cited by 166 · see citing works

Regulation of Cellular Plasticity Cascades in the Pathophysiology and Treatment of Mood Disorders

Zarate, C. A., Du, J., Quiroz, J. A., GRAY, N. A., Denicoff, K. D., Singh, J., Charney, D. S., & Manji, H. K. (2003) · Annals of the New York Academy of Sciences · doi:10.1196/annals.1300.017 · Cited by 164 · see citing works

A neuropharmacologically-relevant animal model of depression

Sherman, A. D., Allers, G. L., Petty, F., et al. (1979) · Neuropharmacology · doi:10.1016/0028-3908(79)90087-x · Cited by 162 · see citing works

Clinical Studies Implementing Glutamate Neurotransmission in Mood Disorders

Sanacora, G., Rothman, D. L., Mason, G. F., & Krystal, J. H. (2003) · Annals of the New York Academy of Sciences · doi:10.1196/annals.1300.018 · Cited by 157 · see citing works

GABA and glutamate systems as therapeutic targets in depression and mood disorders

Kendell, S. F., Krystal, J. H., & Sanacora, G. (2005) · Expert Opinion on Therapeutic Targets · doi:10.1517/14728222.9.1.153 · Cited by 151 · see citing works

Antidepressant-Like Effects of Ceftriaxone in Male C57BL/6J Mice

Mineur, Y. S., Picciotto, M. R., & Sanacora, G. (2006) · Biological Psychiatry · doi:10.1016/j.biopsych.2006.04.037 · Cited by 150 · see citing works

Brain Systems Underlying Susceptibility to Helplessness and Depression

Shumake, J., & Gonzalez-Lima, F. (2003) · Behavioral and Cognitive Neuroscience Reviews · doi:10.1177/1534582303259057 · Cited by 135 · see citing works

Depression: What We can Learn from Postmortem Studies

Rajkowska, G. (2003) · The Neuroscientist · doi:10.1177/1073858403252773 · Cited by 114 · see citing works

Rats with congenital learned helplessness respond less to sucrose but show no deficits in activity or learning

Vollmayr, B., Bachteler, D., Vengeliene, V., Gass, P., Spanagel, R., & Henn, F. A. (2003) · Behavioural Brain Research · doi:10.1016/s0166-4328(03)00259-6 · Cited by 113 · see citing works

Involvement of AMPA receptors in the antidepressant-like effects of lithium in the mouse tail suspension test and forced swim test

Gould, T. D., O’Donnell, K. C., Dow, E. R., Du, J., Chen, G., & Manji, H. K. (2007) · Neuropharmacology · doi:10.1016/j.neuropharm.2007.11.002 · Cited by 103 · see citing works

Brain-derived-neurotrophic-factor (BDNF) stress response in rats bred for learned helplessness

Vollmayr, B., Faust, H., Lewicka, S., & Henn, F. A. (2001) · Molecular Psychiatry · doi:10.1038/sj.mp.4000907 · Cited by 100 · see citing works

Retrosplenial cortex lesions of area Rgb (but not of area Rga) impair spatial learning and memory in the rat

van Groen, T., Kadish, I., & Wyss, J. M. (2004) · Behavioural Brain Research · doi:10.1016/j.bbr.2004.03.016 · Cited by 90 · see citing works

Selective cortical VGLUT1 increase as a marker for antidepressant activity

Moutsimilli, L., Farley, S., Dumas, S., Mestikawy, S. E., Bruno Giros, A., & Tzavara, E. T. (2005) · Neuropharmacology · doi:10.1016/j.neuropharm.2005.06.017 · Cited by 88 · see citing works

Vesicular release of glutamate mediates bidirectional signaling between astrocytes and neurons

Ni, Y., Malarkey, E. B., & Parpura, V. (2007) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.2007.04864.x · Cited by 87 · see citing works

Elevated spectroscopic glutamate/&ggr;-amino butyric acid in rats bred for learned helplessness

Sartorius, A., Mahlstedt, M. M., Vollmayr, B., Henn, F., & Ende, G. (2007) · NeuroReport · doi:10.1097/wnr.0b013e3282742153 · Cited by 85 · see citing works

Stress, Synaptic Plasticity, and Psychopathology

Garcia, R. (2002) · Reviews in the Neurosciences · doi:10.1515/revneuro.2002.13.3.195 · Cited by 81 · see citing works

Neurotransmission and glial cells: A functional relationship?

Henn, F. A. (1976) · Journal of Neuroscience Research · doi:10.1002/jnr.490020404 · Cited by 73 · see citing works

Impaired escape performance and enhanced conditioned fear in rats following exposure to an uncontrollable stressor are mediated by glutamate and nitric oxide in the dorsal raphe nucleus

Grahn, R. E., Watkins, L. R., & Maier, S. F. (2000) · Behavioural Brain Research · doi:10.1016/s0166-4328(00)00161-3 · Cited by 68 · see citing works

Congenital helpless rats as a genetic model for cortex metabolism in depression

Shumake, J., Poremba, A., Edwards, E., & Gonzalez-Lima, F. (2000) · Neuroreport · doi:10.1097/00001756-200011270-00040 · Cited by 65 · see citing works

Glia mechanisms in mood regulation: a novel model of mood disorders

Lee, Y., Gaskins, D. L., Anand, A., & Shekhar, A. (2007) · Psychopharmacology · doi:10.1007/s00213-006-0652-4 · Cited by 64 · see citing works

Evidence for increased expression of the vesicular glutamate transporter, VGLUT1, by a course of antidepressant treatment

Tordera, R. M., Pei, Q., & Sharp, T. (2005) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.2005.03192.x · Cited by 61 · see citing works

Brain differences in newborn rats predisposed to helpless and depressive behavior

Shumake, J., Conejo, N. M., González‐Pardo, H., & Gonzalez-Lima, F. (2004) · Brain Research · doi:10.1016/j.brainres.2004.10.015 · Cited by 57 · see citing works

Treating Neurodegenerative Diseases with Antibiotics

Miller, T. M., & Cleveland, D. W. (2005) · Science · doi:10.1126/science.1109027 · Cited by 52 · see citing works

Control of ACTH Secretion by Excitatory Amino Acids: Functional Significance and Clinical Implications

Ježová, D. (2005) · Endocrine · doi:10.1385/endo:28:3:287 · Cited by 50 · see citing works

Glucocorticoid Regulation of GLT-1 Glutamate Transporter Isoform Expression in the Rat Hippocampus

Autry, A. E., Grillo, C. A., Piroli, G. G., Rothstein, J. D., McEwen, B. S., & Reagan, L. P. (2006) · Neuroendocrinology · doi:10.1159/000096092 · Cited by 49 · see citing works

Major depression: emerging therapeutics

Sen, S., & Sanacora, G. (2008) · Mount Sinai Journal of Medicine A Journal of Translational and Personalized Medicine · doi:10.1002/msj.20043 · Cited by 48 · see citing works

Chronic treatment with fluoxetine decreases seizure threshold in naïve but not in rats exposed to the learned helplessness paradigm: Correlation with the hippocampal glutamate release

Ferrero, A. J., Cereseto, M., Reinés, A. G., Bonavita, C. D., Sifonios, L. L., Rubio‐Terres, C., & Wikinski, S. (2005) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2005.04.013 · Cited by 42 · see citing works

Specific creatine rise in learned helplessness induced by electroconvulsive shock treatment

Sartorius, A., Vollmayr, B., Neumann‐Haefelin, C., Ende, G., Hoehn, M., & Henn, F. A. (2003) · Neuroreport · doi:10.1097/00001756-200312020-00013 · Cited by 38 · see citing works

Reduced Expression of GABA Transporter GAT3 in Helpless Rats, an Animal Model of Depression

Zink, M., Vollmayr, B., Gebicke‐Haerter, P. J., & Henn, F. A. (2009) · Neurochemical Research · doi:10.1007/s11064-009-9947-2 · Cited by 35 · see citing works

Voluntary alcohol intake in two rat lines selectively bred for learned helpless and non-helpless behavior

Vengeliene, V., Vollmayr, B., Henn, F. A., & Spanagel, R. (2004) · Psychopharmacology · doi:10.1007/s00213-004-2013-5 · Cited by 34 · see citing works

Differential expression of glutamate transporter genes after chronic oral treatment with aripiprazole in rats

Segnitz, N., Schmitt, A., Gebicke‐Haerter, P. J., & Zink, M. (2009) · Neurochemistry International · doi:10.1016/j.neuint.2009.06.003 · Cited by 31 · see citing works

Helplessness and escape performance: glutamate-adenosine interactions in the frontal cortex.

Hunter, A. M., Balleine, B., & Minor, T. (2003) · Behavioral Neuroscience · doi:10.1037//0735-7044.117.1.123 · Cited by 29 · see citing works

Intracortical glutamate injection produces helpless-like behavior in the rat.

Petty, F., McChesney, C., & Kramer, G. (1985) · Pharmacology, Biochemistry and Behavior · doi:10.1016/0091-3057(85)90270-9 · Cited by 26 · see citing works

Antidepressants differentially affect expression of complexin I and II RNA in rat hippocampus

Zink, M., Rapp, S., Gebicke‐Haerter, P. J., Henn, F. A., & Thome, J. (2005) · Psychopharmacology · doi:10.1007/s00213-005-0017-4 · Cited by 25 · see citing works

Helplessness and escape performance: Glutamate-adenosine interactions in the frontal cortex.

Hunter, A. M., Balleine, B. W., & Minor, T. R. (2003) · Behavioral Neuroscience · doi:10.1037/0735-7044.117.1.123 · Cited by 20 · see citing works

Reduced expression of complexins I and II in rats bred for learned helplessness

Zink, M., Vollmayr, B., Gebicke‐Haerter, P. J., Henn, F. A., & Thome, J. (2007) · Brain Research · doi:10.1016/j.brainres.2007.01.066 · Cited by 14 · see citing works

Glutamatergic components of the retrosplenial granular cortex in the rat

Wang, B., Gonzalo‐Ruiz, A., Sanz, J. M., et al. (2002) · Journal of Neurocytology · doi:10.1023/a:1015069727171 · Cited by 13 · see citing works

Modulation of neuronal glutamate transporter rEAAC1 mRNA expression in rat brain by amitriptyline

Andin, J., Stenfors, C., Ross, S. B., & Marcusson, J. O. (2004) · Molecular Brain Research · doi:10.1016/j.molbrainres.2004.03.023 · Cited by 7 · see citing works

The stressed synapse: the impact of stress and glucocorticoids on glutamate transmission

Popoli, M., Yan, Z., McEwen, B. S., & Sanacora, G. (2012) · Nature Reviews Neuroscience · doi:10.1038/nrn3138 · Cited by 1,393 · see citing works

Towards a glutamate hypothesis of depression

Sanacora, G., Treccani, G., & Popoli, M. (2012) · Neuropharmacology · doi:10.1016/j.neuropharm.2011.07.036 · Cited by 1,036 · see citing works

Pathogenesis of depression: Insights from human and rodent studies

Ménard, C., Hodes, G. E., & Russo, S. J. (2016) · Neuroscience · doi:10.1016/j.neuroscience.2015.05.053 · Cited by 593 · see citing works

Neural Mechanisms of Stress Resilience and Vulnerability

Franklin, T. B., Saab, B. J., & Mansuy, I. M. (2012) · Neuron · doi:10.1016/j.neuron.2012.08.016 · Cited by 500 · see citing works

Altered expression of glutamate signaling, growth factor, and glia genes in the locus coeruleus of patients with major depression

Bernard, R., Kerman, I. A., Thompson, R. C., Jones, E. G., Bunney, W. E., Barchas, J. D., Schatzberg, A. F., Myers, R. M., Akil, H., & Watson, S. J. (2011) · Molecular Psychiatry · doi:10.1038/mp.2010.44 · Cited by 372 · see citing works

GluN2B-containing NMDA receptors regulate depression-like behavior and are critical for the rapid antidepressant actions of ketamine

Miller, O. H., Yang, L., Wang, C.-C., Hargroder, E. A., Zhang, Y., Delpire, E., & Hall, B. J. (2014) · eLife · doi:10.7554/elife.03581 · Cited by 358 · see citing works

Morphological, cellular and molecular basis of brain infection in COVID-19 patients

Crunfli, F., Carregari, V. C., Veras, F. P., Vendramini, P. H., Valença, A. G. F., Antunes, A. S. L. M., Brandão-Teles, C., da Silva Zuccoli, G., Reis-de-Oliveira, G., Silva-Costa, L. C., et al. (2020) · doi:10.1101/2020.10.09.20207464 · Cited by 331 · see citing works

Discovering imaging endophenotypes for major depression

Hasler, G., & Northoff, G. (2011) · Molecular Psychiatry · doi:10.1038/mp.2011.23 · Cited by 274 · see citing works

Density of GFAP-immunoreactive astrocytes is decreased in left hippocampi in major depressive disorder

Cobb, J. A., O’Neill, K., Milner, J., Mahajan, G. J., Lawrence, T. J., May, W. L., Miguel-Hidalgo, J., Rajkowska, G., & Stockmeier, C. A. (2016) · Neuroscience · doi:10.1016/j.neuroscience.2015.12.044 · Cited by 254 · see citing works

An astroglial basis of major depressive disorder? An overview

Wang, Q., Jie, W., Liu, J., Yang, J., & Gao, T. (2017) · Glia · doi:10.1002/glia.23143 · Cited by 222 · see citing works

From Pathophysiology to Novel Antidepressant Drugs: Glial Contributions to the Pathology and Treatment of Mood Disorders

Sanacora, G., & Banasr, M. (2013) · Biological Psychiatry · doi:10.1016/j.biopsych.2013.03.032 · Cited by 239 · see citing works

The molecular and cellular mechanisms of depression: a focus on reward circuitry

Fox, M. E., & Lobo, M. K. (2019) · Molecular Psychiatry · doi:10.1038/s41380-019-0415-3 · Cited by 232 · see citing works

Two cellular hypotheses explaining the initiation of ketamine's antidepressant actions: Direct inhibition and disinhibition

Miller, O. H., Moran, J. T., & Hall, B. J. (2016) · Neuropharmacology · doi:10.1016/j.neuropharm.2015.07.028 · Cited by 200 · see citing works

Cell atrophy and loss in depression: reversal by antidepressant treatment

Banasr, M., Dwyer, J. M., & Duman, R. S. (2011) · Current Opinion in Cell Biology · doi:10.1016/j.ceb.2011.09.002 · Cited by 201 · see citing works

Agomelatine: Mechanism of action and pharmacological profile in relation to antidepressant properties

Guardiola‐Lemaitre, B., De Bodinat, C., Delagrange, P., Millan, M. J., Munoz, C., & Mocaër, E. (2014) · British Journal of Pharmacology · doi:10.1111/bph.12720 · Cited by 182 · see citing works

Glial Dysfunction in the Mouse Habenula Causes Depressive-Like Behaviors and Sleep Disturbance

Cui, W., Mizukami, H., Yanagisawa, M., Aida, T., Nomura, M., Isomura, Y., Takayanagi, R., Ozawa, K., Tanaka, K., & Aizawa, H. (2014) · The Journal of Neuroscience · doi:10.1523/jneurosci.1465-14.2014 · Cited by 139 · see citing works

Fractionating Blunted Reward Processing Characteristic of Anhedonia by Over-Activating Primate Subgenual Anterior Cingulate Cortex

Alexander, L., Gaskin, P. L. R., Sawiak, S. J., Fryer, T. D., Hong, Y. T., Cockcroft, G. J., Clarke, H. F., & Roberts, A. C. (2019) · Neuron · doi:10.1016/j.neuron.2018.11.021 · Cited by 120 · see citing works

Glutamine deficiency in the prefrontal cortex increases depressive-like behaviours in male mice

Lee, Y., Son, H., Kim, G., Kim, S., Lee, D. H., Roh, G. S., Kang, S. S., Cho, G. J., Choi, W. S., & Kim, H. J. (2013) · Journal of Psychiatry & Neuroscience · doi:10.1503/jpn.120024 · Cited by 94 · see citing works

Aquaporin‐4 Knockout Exacerbates Corticosterone‐Induced Depression by Inhibiting Astrocyte Function and Hippocampal Neurogenesis

Kong, H., Zeng, X., Fan, Y., Yuan, S., Ge, S., Xie, W., Wang, H., & Hu, G. (2014) · CNS Neuroscience & Therapeutics · doi:10.1111/cns.12222 · Cited by 72 · see citing works

Glutamate transport: a new bench to bedside mechanism for treating drug abuse

Spencer, S., & Kalivas, P. W. (2017) · International Journal of Neuropsychopharmacology · doi:10.1093/ijnp/pyx050 · Cited by 71 · see citing works

Glutamate transporter 1-mediated antidepressant-like effect in a rat model of chronic unpredictable stress

Chen, J.-X., Yao, L.-H., Xu, B.-B., Qian, K., Wang, H.-L., Liu, Z.-C., Wang, X.-P., & Wang, G.-H. (2014) · Journal of Huazhong University of Science and Technology [Medical Sciences] · doi:10.1007/s11596-014-1362-5 · Cited by 39 · see citing works

EAT-4, a Homolog of a Mammalian Sodium-Dependent Inorganic Phosphate Cotransporter, Is Necessary for Glutamatergic Neurotransmission inCaenorhabditis elegans

Lee, R., Sawin, E. R., Chalfie, M., Horvitz, H. R., & Avery, L. (1999) · Journal of Neuroscience · doi:10.1523/jneurosci.19-01-00159.1999 · Cited by 351 · see citing works

Glutamatergic Neurotransmission, Aluminium and Alzheimer’s Disease

Felipo, V. (2001) · Elsevier eBooks · doi:10.1016/b978-044450811-9/50042-2 · Cited by 1 · see citing works

Energy for Neurotransmission

Hertz, L., & Robinson, S. R. (1999) · Science · doi:10.1126/science.285.5428.639a · Cited by 7 · see citing works

Role of astrocytic transport processes in glutamatergic and GABAergic neurotransmission

Schousboe, A., Sarup, A., Bak, L. K., Waagepetersen, H. S., & Larsson, O. M. (2004) · Neurochemistry International · doi:10.1016/j.neuint.2003.11.001 · Cited by 142 · see citing works

Effects of polyamines on synaptic transmission, with special attention to the glutamatergic system.

Piek, T., Schluter, N. C. M., & Karst, H. (1991) · PubMed