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Regulation of AMPAR expression by microRNAs
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“miRNA‐dependent regulation of AMPAR levels may thus be a pervasive mechanism of controlling excitatory synaptic strength (Hanley, 2021).”
From MicroRNA‐138‐5p suppresses excitatory synaptic strength at the cerebellar input layer (2025) · cites this paper as Hanley, 2021
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Activity-dependent scaling of quantal amplitude in neocortical neurons
Turrigiano, G. G., Leslie, K. R., Desai, N. S., Rutherford, L. C., & Nelson, S. B. (1998) · Nature · doi:10.1038/36103 · Cited by 2,226
Long-term depression in the CNS
Collingridge, G. L., Peineau, S., Howland, J. G., & Wang, Y. T. (2010) · Nature Reviews Neuroscience · doi:10.1038/nrn2867 · Cited by 926
The AMPA Receptor Code of Synaptic Plasticity
Diering, G. H., & Huganir, R. L. (2018) · Neuron · doi:10.1016/j.neuron.2018.10.018 · Cited by 844 · cited 2×
“…or decreases in synaptic strength (synaptic plasticity) modify the functional connectivity of neuronal circuits and consequently underpin processes of learning and the formation or loss of memories (Diering and Huganir, 2018; Hardt et al., 2014; Huganir and Nicoll, 2013; Kessels and Malinow, 2009).”
AU-rich-element-mediated upregulation of translation by FXR1 and Argonaute 2
Vasudevan, S., & Steitz, J. A. (2007) · Cell · doi:10.1016/j.cell.2007.01.038 · Cited by 656
Regulation of AMPA receptor trafficking and synaptic plasticity
Anggono, V., & Huganir, R. L. (2012) · Current Opinion in Neurobiology · doi:10.1016/j.conb.2011.12.006 · Cited by 588 · cited 2×
“…Potentiation (LTP) and Long-Term Depression (LTD), which are triggered typically by NMDAR stimulation, or in some forms of LTD, by mGluR stimulation, both of which activate various signalling pathways that result in changes in AMPAR trafficking (Anggono and Huganir, 2012; Chater and Goda, 2014).”
Moore, M. J., Scheel, T. K. H., Luna, J. M., Park, C. Y., Fak, J. J., Nishiuchi, E., Rice, C. M., & Darnell, R. B. (2015) · Nature Communications · doi:10.1038/ncomms9864 · Cited by 326
A three-step model for the synaptic recruitment of AMPA receptors
Opazo, P., & Choquet, D. (2011) · Molecular and Cellular Neuroscience · doi:10.1016/j.mcn.2010.08.014 · Cited by 190
Postsynaptic Complexin Controls AMPA Receptor Exocytosis during LTP
Ahmad, M., Polepalli, J. S., Goswami, D., Yang, X., Kaeser-Woo, Y. J., Südhof, T. C., & Malenka, R. C. (2012) · Neuron · doi:10.1016/j.neuron.2011.11.020 · Cited by 133
The Brain-Enriched MicroRNA miR-9-3p Regulates Synaptic Plasticity and Memory
Sim, S.-E., Lim, C.-S., Kim, J.-I., Seo, D., Chun, H., Yu, N.-K., Lee, J., Kang, S. J., Ko, H.-G., Choi, J.-H., et al. (2016) · The Journal of Neuroscience · doi:10.1523/jneurosci.0630-16.2016 · Cited by 116
Research works printed but not linked: 69
- Aksoy-Aksel, 2014, MicroRNAs and synaptic plasticity--a mutual relationship, Philos. Trans. R. Soc. Lond. B Biol. Sci., 369, 10.1098/rstb.2013.0515 · DOI
- Amoah, 2020, Exosomal secretion of a psychosis-altered miRNA that regulates glutamate receptor expression is affected by antipsychotics, Neuropsychopharmacology, 45, 656, 10.1038/s41386-019-0579-1 · DOI
- Ansari, 2019, miR-146a and miR-181a are involved in the progression of mild cognitive impairment to Alzheimer's disease, Neurobiol. Aging, 82, 102, 10.1016/j.neurobiolaging.2019.06.005 · DOI
- Benoist, 2013, MAP1B-dependent Rac activation is required for AMPA receptor endocytosis during long-term depression, EMBO J., 32, 2287, 10.1038/emboj.2013.166 · DOI
- Chater, 2014, The role of AMPA receptors in postsynaptic mechanisms of synaptic plasticity, Front. Cell. Neurosci., 8, 401, 10.3389/fncel.2014.00401 · DOI
- Chen, 2010, Synaptic plasticity in the mesolimbic system: therapeutic implications for substance abuse, Ann. N. Y. Acad. Sci., 1187, 129, 10.1111/j.1749-6632.2009.05154.x · DOI
- Chen, 2013, Modulation of mGluR-dependent MAP1B translation and AMPA receptor endocytosis by microRNA miR-146a-5p, J. Neurosci., 33, 9013, 10.1523/JNEUROSCI.5210-12.2013 · DOI
- Chowdhury, 2018, Homeostatic synaptic scaling: molecular regulators of synaptic AMPA-type glutamate receptors, F1000Res, 7, 234, 10.12688/f1000research.13561.1 · DOI
- Coffee, 2012, In vivo neuronal function of the fragile X mental retardation protein is regulated by phosphorylation, Hum. Mol. Genet., 21, 900, 10.1093/hmg/ddr527 · DOI
- Coyle, 2020, Fifty years of research on Schizophrenia: the ascendance of the glutamatergic synapse, Am. J. Psychiatr., 177, 1119, 10.1176/appi.ajp.2020.20101481 · DOI
- Davidkova, 2007, Characterization of the role of microtubule-associated protein 1B in metabotropic glutamate receptor-mediated endocytosis of AMPA receptors in hippocampus, J. Neurosci., 27, 13273, 10.1523/JNEUROSCI.3334-07.2007 · DOI
- Dutta, 2013, Hippocampal demyelination and memory dysfunction are associated with increased levels of the neuronal microRNA miR-124 and reduced AMPA receptors, Ann. Neurol., 73, 637, 10.1002/ana.23860 · DOI · Paper page
- Evers, 2010, Plk2 attachment to NSF induces homeostatic removal of GluA2 during chronic overexcitation, Nat. Neurosci., 13, 1199, 10.1038/nn.2624 · DOI
- Fernandes, 2016, Mechanisms of homeostatic plasticity in the excitatory synapse, J. Neurochem., 139, 973, 10.1111/jnc.13687 · DOI
- Fiore, 2014, MiR-134-dependent regulation of Pumilio-2 is necessary for homeostatic synaptic depression, EMBO J., 33, 2231, 10.15252/embj.201487921 · DOI
- Gascon, 2014, Alterations in microRNA-124 and AMPA receptors contribute to social behavioral deficits in frontotemporal dementia, Nat. Med., 20, 1444, 10.1038/nm.3717 · DOI · Paper page
- Gilbert, 2016, beta-Amyloid triggers aberrant over-scaling of homeostatic synaptic plasticity, Acta Neuropathol Commun, 4, 131, 10.1186/s40478-016-0398-0 · DOI
- Goldstrohm, 2018, Post-transcriptional regulatory functions of mammalian Pumilio proteins, Trends Genet., 34, 972, 10.1016/j.tig.2018.09.006 · DOI
- Greger, 2017, Structural and functional architecture of AMPA-type glutamate receptors and their auxiliary proteins, Neuron, 94, 713, 10.1016/j.neuron.2017.04.009 · DOI · Paper page
- Ha, 2014, Regulation of microRNA biogenesis, Nat. Rev. Mol. Cell Biol., 15, 509, 10.1038/nrm3838 · DOI · Paper page
- Hanley, 2014, Subunit-specific trafficking mechanisms regulating the synaptic expression of Ca(2+)-permeable AMPA receptors, Semin. Cell Dev. Biol., 27, 14, 10.1016/j.semcdb.2013.12.002 · DOI
- Hanley, 2018, The regulation of AMPA receptor endocytosis by dynamic protein-protein interactions, Front. Cell. Neurosci., 12, 362, 10.3389/fncel.2018.00362 · DOI
- Hardt, 2014, GluA2-dependent AMPA receptor endocytosis and the decay of early and late long-term potentiation: possible mechanisms for forgetting of short- and long-term memories, Philos T R Soc B, 369, 10.1098/rstb.2013.0141 · DOI
- Harraz, 2012, MicroRNA-223 is neuroprotective by targeting glutamate receptors, Proc. Natl. Acad. Sci. U. S. A., 109, 18962, 10.1073/pnas.1121288109 · DOI · Paper page
- Henley, 2016, Synaptic AMPA receptor composition in development, plasticity and disease, Nat. Rev. Neurosci., 17, 337, 10.1038/nrn.2016.37 · DOI
- Hou, 2015, MicroRNA miR 124 is required for the expression of homeostatic synaptic plasticity, Nat. Commun., 6, 10045, 10.1038/ncomms10045 · DOI
- Hu, 2017, miRNAs in synapse development and synaptic plasticity, Curr. Opin. Neurobiol., 45, 24, 10.1016/j.conb.2017.02.014 · DOI
- Hu, 2014, miR-191 and miR-135 are required for long-lasting spine remodelling associated with synaptic long-term depression, Nat. Commun., 5, 3263, 10.1038/ncomms4263 · DOI
- Hu, 2015, miR-501-3p mediates the activity-dependent regulation of the expression of AMPA receptor subunit GluA1, J. Cell Biol., 208, 949, 10.1083/jcb.201404092 · DOI
- Huganir, 2013, AMPARs and synaptic plasticity: the last 25 years, Neuron, 80, 704, 10.1016/j.neuron.2013.10.025 · DOI · Paper page
- Jacobi, 2021, Modulation of information processing by AMPA receptor auxiliary subunits, J. Physiol., 599, 471, 10.1113/JP276698 · DOI
- Jang, 2016, Emerging link between alzheimer's disease and homeostatic synaptic plasticity, Neural Plast., 2016, 7969272, 10.1155/2016/7969272 · DOI
- Kessels, 2009, Synaptic AMPA receptor plasticity and behavior, Neuron, 61, 340, 10.1016/j.neuron.2009.01.015 · DOI · Paper page
- Kopec, 2007, GluR1 links structural and functional plasticity at excitatory synapses, J. Neurosci., 27, 13706, 10.1523/JNEUROSCI.3503-07.2007 · DOI
- Korb, 2013, Arc in the nucleus regulates PML-dependent GluA1 transcription and homeostatic plasticity, Nat. Neurosci., 16, 874, 10.1038/nn.3429 · DOI
- Lagos-Quintana, 2002, Identification of tissue-specific microRNAs from mouse, Curr. Biol., 12, 735, 10.1016/S0960-9822(02)00809-6 · DOI · Paper page
- Leonard, 1998, SAP97 is associated with the alpha-amino-3-hydroxy-5-methylisoxazole-4-propionic acid receptor GluR1 subunit, J. Biol. Chem., 273, 19518, 10.1074/jbc.273.31.19518 · DOI · Paper page
- Letellier, 2014, miR-92a regulates expression of synaptic GluA1-containing AMPA receptors during homeostatic scaling, Nat. Neurosci., 17, 1040, 10.1038/nn.3762 · DOI · Paper page
- Liu, 2016, miR-218 involvement in cardiomyocyte hypertrophy is likely through targeting REST, Int. J. Mol. Sci., 17
- Liu, 2007, Ca2+-permeable AMPA receptors in synaptic plasticity and neuronal death, Trends Neurosci., 30, 126, 10.1016/j.tins.2007.01.006 · DOI · Paper page
- Lu, 2009, Subunit composition of synaptic AMPA receptors revealed by a single-cell genetic approach, Neuron, 62, 254, 10.1016/j.neuron.2009.02.027 · DOI · Paper page
- McNeill, 2012, MicroRNAs shape the neuronal landscape, Neuron, 75, 363, 10.1016/j.neuron.2012.07.005 · DOI · Paper page
- Meister, 2013, Argonaute proteins: functional insights and emerging roles, Nat. Rev. Genet., 14, 447, 10.1038/nrg3462 · DOI
- Morquette, 2019, MicroRNA-223 protects neurons from degeneration in experimental autoimmune encephalomyelitis, Brain, 142, 2979, 10.1093/brain/awz245 · DOI
- Muddashetty, 2011, Reversible inhibition of PSD-95 mRNA translation by miR-125a, FMRP phosphorylation, and mGluR signaling, Mol. Cell., 42, 673, 10.1016/j.molcel.2011.05.006 · DOI · Paper page
- Myers, 1998, Transcriptional regulation of the GluR2 gene: neural-specific expression, multiple promoters, and regulatory elements, J. Neurosci., 18, 6723, 10.1523/JNEUROSCI.18-17-06723.1998 · DOI
- Nakagawa, 2004, Quaternary structure, protein dynamics, and synaptic function of SAP97 controlled by L27 domain interactions, Neuron, 44, 453, 10.1016/j.neuron.2004.10.012 · DOI · Paper page
- Olde Loohuis, 2015, MicroRNA-137 controls AMPA-receptor-mediated transmission and mGluR-dependent LTD, Cell Rep., 11, 1876, 10.1016/j.celrep.2015.05.040 · DOI · Paper page
- Rajgor, 2018, NMDAR-dependent Argonaute 2 phosphorylation regulates miRNA activity and dendritic spine plasticity, EMBO J., 37, 10.15252/embj.201797943 · DOI
- Rajman, 2017, MicroRNAs in neural development: from master regulators to fine-tuners, Development, 144, 2310, 10.1242/dev.144337 · DOI · Paper page
- Rocchi, 2019, Neurite-enriched MicroRNA-218 stimulates translation of the GluA2 subunit and increases excitatory synaptic strength, Mol. Neurobiol., 56, 5701, 10.1007/s12035-019-1492-7 · DOI
- Rodriguez-Ortiz, 2020, miR-181a negatively modulates synaptic plasticity in hippocampal cultures and its inhibition rescues memory deficits in a mouse model of Alzheimer's disease, Aging Cell, 19, e13118, 10.1111/acel.13118 · DOI
- Saba, 2012, Dopamine-regulated microRNA MiR-181a controls GluA2 surface expression in hippocampal neurons, Mol. Cell Biol., 32, 619, 10.1128/MCB.05896-11 · DOI · Paper page
- Sambandan, 2017, Activity-dependent spatially localized miRNA maturation in neuronal dendrites, Science, 355, 634, 10.1126/science.aaf8995 · DOI
- Santarelli, 2013, Gene-microRNA interactions associated with antipsychotic mechanisms and the metabolic side effects of olanzapine, Psychopharmacology, 227, 67, 10.1007/s00213-012-2939-y · DOI
- Sanuki, 2011, miR-124a is required for hippocampal axogenesis and retinal cone survival through Lhx2 suppression, Nat. Neurosci., 14, 1125, 10.1038/nn.2897 · DOI
- Schratt, 2006, A brain-specific microRNA regulates dendritic spine development, Nature, 439, 283, 10.1038/nature04367 · DOI · Paper page
- Silva, 2019, MicroRNA-186-5p controls GluA2 surface expression and synaptic scaling in hippocampal neurons, Proc. Natl. Acad. Sci. U. S. A., 116, 5727, 10.1073/pnas.1900338116 · DOI
- Song, 2019, A novel mechanism of synaptic and cognitive impairments mediated via microRNA-30b in Alzheimer's disease, EBioMedicine, 39, 409, 10.1016/j.ebiom.2018.11.059 · DOI
- Thomas, 2018, microRNAs sculpt neuronal communication in a tight balance that is lost in neurological disease, Front. Mol. Neurosci., 11, 455, 10.3389/fnmol.2018.00455 · DOI · Paper page
- Treiber, 2019, Regulation of microRNA biogenesis and its crosstalk with other cellular pathways, Nat. Rev. Mol. Cell Biol., 20, 5, 10.1038/s41580-018-0059-1 · DOI
- Vazquez, 2010, Silencing of hsa-miR-124 by EVI1 in cell lines and patients with acute myeloid leukemia, Proc. Natl. Acad. Sci. U. S. A., 107, E167, 10.1073/pnas.1011540107 · DOI
- Wang, 2012, AMPA receptor trafficking in homeostatic synaptic plasticity: functional molecules and signaling cascades, Neural Plast., 825364
- Wang, 2012, MicroRNAs in learning, memory, and neurological diseases, Learn. Mem., 19, 359, 10.1101/lm.026492.112 · DOI
- Waung, 2009, Protein translation in synaptic plasticity: mGluR-LTD, Fragile X, Curr. Opin. Neurobiol., 19, 319, 10.1016/j.conb.2009.03.011 · DOI
- Weiss, 2015, Non-coding mechanisms of local mRNA translation in neuronal dendrites, Eur. J. Cell Biol., 94, 363, 10.1016/j.ejcb.2015.05.011 · DOI
- Wenthold, 1996, Evidence for multiple AMPA receptor complexes in hippocampal CA1/CA2 neurons, J. Neurosci., 16, 1982, 10.1523/JNEUROSCI.16-06-01982.1996 · DOI · Paper page
- Wilson, 2013, Molecular mechanisms of RNA interference, Annu. Rev. Biophys., 42, 217, 10.1146/annurev-biophys-083012-130404 · DOI
- Wolf, 2012, Calcium-permeable AMPA receptors in the VTA and nucleus accumbens after cocaine exposure: when, how, and why?, Front. Mol. Neurosci., 5, 72, 10.3389/fnmol.2012.00072 · DOI
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MicroRNA‐138‐5p suppresses excitatory synaptic strength at the cerebellar input layer
Delvendahl, I., Daswani, R., Winterer, J., Germain, P., Uhr, N. M., Schratt, G., & Müller, M. (2025) · The Journal of Physiology · doi:10.1113/jp288019 · Cited by 3
Metadata
- Authors
- Hanley, J. G.
- ORCID
- Hanley, Jonathan G.
- Venue
- Neuropharmacology
- Publisher
- Elsevier BV
- Published
- 2021-10
- Volume
- 197
- Pages
- 108723
- ISSN
- 0028-3908
- Cited by
- 16
- References
- 9
- Language
- en
- Licence
- Funders
- Biotechnology and Biological Sciences Research Council
- Alzheimer’s Research UK
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