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Alterations in microRNA-124 and AMPA receptors contribute to social behavioral deficits in frontotemporal dementia
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“For instance, miR-124-3p was found to be decreased in the frontal lobe of C9ORF72 and MAPT carriers in our study, which is consistent with its association with synaptic dysfunction mediated by CHMP2B mutations, another risk gene for FTD [42].”
From A role for astrocytic miR-129-5p in frontotemporal dementia (2025) · cites this paper as [42]
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Identification of MicroRNA-124-3p as a Putative Epigenetic Signature of Major Depressive Disorder
Roy, B., Dunbar, M., Shelton, R. C., & Dwivedi, Y. (2017) · Neuropsychopharmacology · doi:10.1038/npp.2016.175 · Cited by 199
Hippocampal MicroRNA-124 Enhances Chronic Stress Resilience in Mice
Higuchi, F., Uchida, S., Yamagata, H., Abe-Higuchi, N., Hobara, T., Hara, K., Kobayashi, A., Shintaku, T., Itoh, Y., Suzuki, T., et al. (2016) · Journal of Neuroscience · doi:10.1523/jneurosci.0319-16.2016 · Cited by 158
Gómez de San José, N., Massa, F., Halbgebauer, S., Oeckl, P., Steinacker, P., & Otto, M. (2022) · Journal of Neural Transmission · doi:10.1007/s00702-021-02411-2 · Cited by 112
The FReJA consortium, Clayton, E. L., Mizielinska, S., Edgar, J. R., Nielsen, T. T., Marshall, S., Norona, F. E., Robbins, M., Damirji, H., Holm, I. E., et al. (2015) · Acta Neuropathologica · doi:10.1007/s00401-015-1475-3 · Cited by 96
Synaptic dysfunction and altered excitability in C9ORF72 ALS/FTD
Starr, A., & Sattler, R. (2018) · Brain Research · doi:10.1016/j.brainres.2018.02.011 · Cited by 78
Metadata
- Authors
- Gascon, E., Lynch, K., Ruan, H., Almeida, S., Verheyden, J. M., Seeley, W. W., Dickson, D. W., Petrucelli, L., Sun, D., Jiao, J., Zhou, H., Jakovcevski, M., Akbarian, S., Yao, W.-D., & Gao, F.-B.
- Venue
- Nature Medicine
- Published
- 2014-11-17
- Volume
- 20
- Issue
- 12
- Pages
- 1444-1451
- ISSN
- 1078-8956
- 1546-170X
- PMC
- PMC4257887
- Cited by
- 183
- References
- 11
- Language
- en
- Licence
- www.springer.com/tdm (tdm)
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